SIMILAR PATTERNS OF AMINO ACIDS FOR 2YA7_D_ZMRD1776_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpt CYTOCHROME P450-TERP

(Pseudomonas sp.) 		PF00067
(p450) 		4 ASP A 359
ILE A 360
LEU A 299
GLU A 288
 None
 1.03A 2ya7D-1cptA:
undetectable		 2ya7D-1cptA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dd5 RIBOSOME RECYCLING
FACTOR

(Thermotoga
maritima) 		PF01765
(RRF) 		4 ARG A 129
ILE A  20
LEU A  24
GLU A 119
 None
 0.95A 2ya7D-1dd5A:
undetectable		 2ya7D-1dd5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxl DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pisum sativum) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 277
ILE A  51
LEU A  98
TYR A  19
 FAD  A 480 (-3.5A)
None
None
None
 1.00A 2ya7D-1dxlA:
0.0		 2ya7D-1dxlA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN

(Escherichia
virus T4) 		PF13597
(NRDD) 		4 ASP A 325
ILE A 322
LEU A 317
GLU A 343
 None
 0.85A 2ya7D-1h79A:
0.0		 2ya7D-1h79A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv5 STROMELYSIN 3

(Mus musculus) 		PF00413
(Peptidase_M10) 		4 ARG A 191
ASP A 158
ILE A 159
LEU A 138
 None
CPS  A5006 ( 4.9A)
None
None
 0.94A 2ya7D-1hv5A:
0.0		 2ya7D-1hv5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv8 PUTATIVE
ATP-DEPENDENT RNA
HELICASE MJ0669

(Methanocaldococcus
jannaschii) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 ASP A 154
ILE A  79
LEU A  65
GLU A  93
 None
None
None
SO4  A 803 ( 4.7A)
 1.02A 2ya7D-1hv8A:
undetectable		 2ya7D-1hv8A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8f ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN

(Homo sapiens) 		PF08603
(CAP_C) 		4 ASP A 383
ILE A 363
LEU A 361
GLU A 343
 None
 0.90A 2ya7D-1k8fA:
0.0		 2ya7D-1k8fA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 266
ILE A  49
LEU A  98
TYR A  18
 FAD  A 459 ( 3.9A)
None
None
None
 1.02A 2ya7D-1lvlA:
0.0		 2ya7D-1lvlA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mn6 POLYKETIDE SYNTHASE
IV

(Streptomyces
venezuelae) 		PF00975
(Thioesterase) 		4 ARG A 163
ILE A 172
LEU A 174
GLU A 156
 None
 1.06A 2ya7D-1mn6A:
undetectable		 2ya7D-1mn6A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nio B-LUFFIN

(Luffa
aegyptiaca) 		PF00161
(RIP) 		4 ARG A 163
ILE A 154
LEU A 139
TYR A 107
 None
 1.05A 2ya7D-1nioA:
undetectable		 2ya7D-1nioA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4z BETA-AGARASE B

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		4 ASP A 103
ILE A 147
LEU A 129
TYR A  86
 None
 1.06A 2ya7D-1o4zA:
1.5		 2ya7D-1o4zA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oz9 HYPOTHETICAL PROTEIN
AQ_1354

(Aquifex
aeolicus) 		PF02130
(UPF0054) 		4 ASP A  23
ILE A  25
LEU A  15
GLU A 106
 None
 1.07A 2ya7D-1oz9A:
undetectable		 2ya7D-1oz9A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ty2 PUTATIVE EXOTOXIN
(SUPERANTIGEN)

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 ASP A 135
ILE A 138
LEU A 142
TYR A 175
 None
 1.03A 2ya7D-1ty2A:
undetectable		 2ya7D-1ty2A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vph HYPOTHETICAL PROTEIN
SSO2532

(Sulfolobus
solfataricus) 		PF01894
(UPF0047) 		4 ASP A  62
ILE A  63
LEU A  18
GLU A  54
 None
 0.85A 2ya7D-1vphA:
undetectable		 2ya7D-1vphA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6v UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15

(Homo sapiens) 		PF06337
(DUSP) 		4 ASP A  15
ILE A  16
LEU A 100
GLU A  95
 None
 1.07A 2ya7D-1w6vA:
undetectable		 2ya7D-1w6vA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI

(Escherichia
coli) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ASP A 291
ILE A 290
LEU A 340
GLU A 283
 None
 1.01A 2ya7D-1we5A:
2.2		 2ya7D-1we5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg8 HYPOTHETICAL PROTEIN
SA0798

(Staphylococcus
aureus) 		PF07315
(DUF1462) 		4 ASP A  45
ILE A  44
LEU A  53
GLU A  65
 None
 0.85A 2ya7D-1xg8A:
undetectable		 2ya7D-1xg8A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xu1 TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER
13

(Mus musculus) 		PF00229
(TNF) 		4 ASP A 214
ILE A 216
LEU A 156
GLU A 182
 None
 0.94A 2ya7D-1xu1A:
undetectable		 2ya7D-1xu1A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a33 HYPOTHETICAL PROTEIN

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		4 ASP A 111
ILE A  16
LEU A  41
GLU A 189
 None
 0.99A 2ya7D-2a33A:
undetectable		 2ya7D-2a33A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaf ARGININE DEIMINASE

(Pseudomonas
aeruginosa) 		PF02274
(Amidinotransf) 		4 ARG A  63
ASP A  68
ILE A 411
LEU A   8
 None
 1.04A 2ya7D-2aafA:
undetectable		 2ya7D-2aafA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC

(Homo sapiens) 		PF01063
(Aminotran_4) 		4 ASP A 340
ILE A 350
LEU A 318
GLU A 354
 None
 0.96A 2ya7D-2abjA:
undetectable		 2ya7D-2abjA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axp HYPOTHETICAL PROTEIN
BSU20280

(Bacillus
subtilis) 		PF02223
(Thymidylate_kin) 		4 ASP A  10
ILE A 108
LEU A 129
GLU A 121
 None
 0.96A 2ya7D-2axpA:
undetectable		 2ya7D-2axpA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ASP A1099
ILE A1100
LEU A1058
TYR A  58
 None
 1.04A 2ya7D-2b5mA:
8.3		 2ya7D-2b5mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg8 DIHYDRONEOPTERIN
ALDOLASE
6-HYDROXYMETHYL-7,8-
DIHYDROPTERIN
SYNTHASE

(Streptococcus
pneumoniae) 		PF01288
(HPPK)
PF02152
(FolB) 		4 ARG A 238
ILE A 124
LEU A 187
GLU A 195
 None
 1.04A 2ya7D-2cg8A:
2.2		 2ya7D-2cg8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfk COLLYBISTIN II

(Rattus
norvegicus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ASP A 314
ILE A 313
LEU A 341
GLU A 370
 None
 1.01A 2ya7D-2dfkA:
undetectable		 2ya7D-2dfkA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 ARG A1067
ILE A 529
LEU A 511
GLU A 487
 None
 0.86A 2ya7D-2eyqA:
2.0		 2ya7D-2eyqA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fef HYPOTHETICAL PROTEIN
PA2201

(Pseudomonas
aeruginosa) 		PF08929
(DUF1911) 		4 ASP A  92
ILE A  91
LEU A 281
TYR A 230
 None
 1.04A 2ya7D-2fefA:
undetectable		 2ya7D-2fefA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ija ARYLAMINE
N-ACETYLTRANSFERASE
1

(Homo sapiens) 		PF00797
(Acetyltransf_2) 		4 ASP A 251
ILE A 253
LEU A 181
TYR A 129
 None
 1.06A 2ya7D-2ijaA:
undetectable		 2ya7D-2ijaA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nef NEGATIVE FACTOR
(F-PROTEIN)

(Human
immunodeficiency
virus 1) 		PF00469
(F-protein) 		4 ASP A 111
ILE A 114
LEU A  87
TYR A 143
 None
 1.04A 2ya7D-2nefA:
undetectable		 2ya7D-2nefA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqa LUFFACULIN 1

(Luffa
acutangula) 		PF00161
(RIP) 		4 ARG A 162
ILE A 153
LEU A 138
TYR A 106
 None
 1.06A 2ya7D-2oqaA:
undetectable		 2ya7D-2oqaA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Ruegeria sp.
TM1040) 		PF02627
(CMD) 		4 ASP A 159
ILE A 160
LEU A 147
GLU A  71
 None
 1.00A 2ya7D-2pfxA:
undetectable		 2ya7D-2pfxA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkh HISTIDINE
UTILIZATION
REPRESSOR

(Pseudomonas
syringae group
genomosp. 3) 		PF07702
(UTRA) 		5 ARG A 126
ASP A 156
ILE A 235
LEU A 207
GLU A 200
 None
None
None
None
EDO  A1014 (-4.2A)
 1.43A 2ya7D-2pkhA:
2.1		 2ya7D-2pkhA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Cupriavidus
pinatubonensis) 		PF02627
(CMD) 		4 ASP A 160
ILE A 161
LEU A 148
GLU A  72
 None
 0.99A 2ya7D-2prrA:
undetectable		 2ya7D-2prrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qae DIHYDROLIPOYL
DEHYDROGENASE

(Trypanosoma
cruzi) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 274
ILE A  47
LEU A  95
TYR A  15
 FAD  A 480 (-3.9A)
None
None
None
 1.07A 2ya7D-2qaeA:
undetectable		 2ya7D-2qaeA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT

(Pseudomonas
putida) 		PF00355
(Rieske) 		4 ASP A 101
ILE A 100
LEU A  28
GLU A  24
 None
 0.96A 2ya7D-2qpzA:
undetectable		 2ya7D-2qpzA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qxx DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE

(Mycobacterium
tuberculosis) 		PF00692
(dUTPase) 		4 ARG A 188
ASP A  52
ILE A  51
LEU A  60
 None
 0.95A 2ya7D-2qxxA:
undetectable		 2ya7D-2qxxA:
17.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		5 ASP A 372
ILE A 442
LEU A 598
GLU A 647
TYR A 695
 None
 0.74A 2ya7D-2w20A:
67.7		 2ya7D-2w20A:
94.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xj9 MIPZ

(Caulobacter
vibrioides) 		PF09140
(MipZ) 		4 ARG A 225
ILE A  21
LEU A 184
GLU A 256
 AGS  A1272 (-3.6A)
None
None
None
 1.04A 2ya7D-2xj9A:
undetectable		 2ya7D-2xj9A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr7 MALONYLTRANSFERASE

(Nicotiana
tabacum) 		PF02458
(Transferase) 		4 ASP A 169
ILE A 173
LEU A  74
TYR A 201
 None
 1.07A 2ya7D-2xr7A:
undetectable		 2ya7D-2xr7A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 ARG A 165
ILE A 169
LEU A 120
GLU A 187
 None
 1.06A 2ya7D-3b02A:
undetectable		 2ya7D-3b02A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1r RIBOKINASE, PUTATIVE

(Burkholderia
thailandensis) 		PF00294
(PfkB) 		4 ARG A 231
ILE A 218
LEU A 259
GLU A 235
 None
 1.04A 2ya7D-3b1rA:
undetectable		 2ya7D-3b1rA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjx HALOCARBOXYLIC ACID
DEHALOGENASE DEHI

(Pseudomonas
putida) 		PF10778
(DehI) 		4 ASP A  97
ILE A 100
LEU A 283
GLU A  88
 None
 0.91A 2ya7D-3bjxA:
undetectable		 2ya7D-3bjxA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c87 ENTEROCHELIN
ESTERASE

(Shigella
flexneri) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 ASP A 233
ILE A 232
LEU A 258
GLU A 243
 None
 1.03A 2ya7D-3c87A:
undetectable		 2ya7D-3c87A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8t FUMARATE LYASE

(Chelativorans
sp. BNC1) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 ASP A 264
ILE A 265
LEU A 359
GLU A 275
 None
 0.95A 2ya7D-3c8tA:
undetectable		 2ya7D-3c8tA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cg3 UPF0100 PROTEIN
PH0151

(Pyrococcus
horikoshii) 		PF13531
(SBP_bac_11) 		4 ARG A 206
ILE A 117
LEU A 245
TYR A 172
 None
 1.03A 2ya7D-3cg3A:
undetectable		 2ya7D-3cg3A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN
RESPIRATORY NITRATE
REDUCTASE 1 BETA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF13247
(Fer4_11)
PF14710
(Nitr_red_alph_N)
PF14711
(Nitr_red_bet_C) 		4 ARG A  90
ILE B  17
LEU A 290
GLU A 269
 None
F3S  B 802 (-4.4A)
None
None
 1.03A 2ya7D-3egwA:
undetectable		 2ya7D-3egwA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN

(Geobacillus
stearothermophilus) 		no annotation 4 ASP A 189
ILE A 190
LEU A 192
GLU A 167
 None
 0.90A 2ya7D-3fpnA:
undetectable		 2ya7D-3fpnA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g4g CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		4 ASP A 540
ILE A 539
LEU A 565
GLU A 570
 None
 1.06A 2ya7D-3g4gA:
undetectable		 2ya7D-3g4gA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqj CELL INHIBITING
FACTOR (CIF)

(Photorhabdus
laumondii) 		PF16374
(CIF) 		4 ASP A 255
ILE A 250
LEU A 179
GLU A 264
 None
 0.99A 2ya7D-3gqjA:
undetectable		 2ya7D-3gqjA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwq D-SERINE DEAMINASE

(Paraburkholderia
xenovorans) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 ASP A 389
ILE A 391
LEU A 377
GLU A 363
 None
 0.93A 2ya7D-3gwqA:
undetectable		 2ya7D-3gwqA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrl ENDONUCLEASE-LIKE
PROTEIN

(Neisseria
gonorrhoeae) 		PF04480
(DUF559) 		4 ASP A  59
ILE A  68
LEU A  90
TYR A  82
 None
 1.04A 2ya7D-3hrlA:
undetectable		 2ya7D-3hrlA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ikm DNA POLYMERASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00476
(DNA_pol_A) 		4 ARG A1234
ILE A1155
LEU A1159
GLU A  85
 None
 1.07A 2ya7D-3ikmA:
undetectable		 2ya7D-3ikmA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lad DIHYDROLIPOAMIDE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 278
ILE A  54
LEU A 101
TYR A  16
 FAD  A 480 (-3.9A)
None
None
None
 1.07A 2ya7D-3ladA:
undetectable		 2ya7D-3ladA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbe TCR 21.3 ALPHA CHAIN

(Mus musculus) 		PF07686
(V-set)
PF09291
(DUF1968) 		4 ASP C  93
ILE C  91
LEU C  79
GLU C  97
 None
 1.04A 2ya7D-3mbeC:
undetectable		 2ya7D-3mbeC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mga ENTEROCHELIN
ESTERASE

(Salmonella
enterica) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 ASP A 238
ILE A 237
LEU A 263
GLU A 248
 None
 1.05A 2ya7D-3mgaA:
undetectable		 2ya7D-3mgaA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nmz APC VARIANT PROTEIN

(Homo sapiens) 		PF00514
(Arm) 		4 ASP A 605
ILE A 606
LEU A 592
GLU A 574
 None
 1.06A 2ya7D-3nmzA:
undetectable		 2ya7D-3nmzA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvs 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Vibrio cholerae) 		PF00275
(EPSP_synthase) 		4 ASP A 112
ILE A 153
LEU A 115
GLU A 141
 None
 1.01A 2ya7D-3nvsA:
undetectable		 2ya7D-3nvsA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pei CYTOSOL
AMINOPEPTIDASE

(Francisella
tularensis) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 ASP A 101
ILE A 100
LEU A 144
GLU A  14
 PEG  A 492 (-4.4A)
None
None
None
 0.96A 2ya7D-3peiA:
undetectable		 2ya7D-3peiA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vcn MANNONATE
DEHYDRATASE

(Caulobacter
vibrioides) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ARG A 343
ILE A 147
LEU A 202
GLU A 135
 GOL  A 506 ( 4.9A)
None
None
None
 0.86A 2ya7D-3vcnA:
0.5		 2ya7D-3vcnA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL

(Arabidopsis
thaliana) 		PF00498
(FHA) 		4 ASP A 115
ILE A 117
LEU A  19
TYR A  67
 None
 1.02A 2ya7D-3vpyA:
2.4		 2ya7D-3vpyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2

(Saccharomyces
cerevisiae) 		PF16834
(CSM2) 		4 ASP B  41
ILE B 116
LEU B  80
GLU B 120
 None
 1.05A 2ya7D-3vu9B:
undetectable		 2ya7D-3vu9B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x05 PHOSPHATIDYLINOSITOL
5-PHOSPHATE 4-KINASE
TYPE-2 BETA

(Homo sapiens) 		PF01504
(PIP5K) 		4 ARG A 224
ILE A 414
LEU A 250
GLU A 246
 None
 1.02A 2ya7D-3x05A:
undetectable		 2ya7D-3x05A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af1 PEPTIDE CHAIN
RELEASE FACTOR
SUBUNIT 1

(Halobacterium
salinarum) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		4 ASP A  86
ILE A  45
LEU A  82
GLU A 116
 None
 1.01A 2ya7D-4af1A:
undetectable		 2ya7D-4af1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aq1 SBSB PROTEIN

(Geobacillus
stearothermophilus) 		no annotation 4 ASP C 656
ILE C 642
LEU C 699
GLU C 706
 None
 0.99A 2ya7D-4aq1C:
undetectable		 2ya7D-4aq1C:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4atf BETA-AGARASE B

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		4 ASP A 103
ILE A 147
LEU A 129
TYR A  86
 None
 1.05A 2ya7D-4atfA:
undetectable		 2ya7D-4atfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 ARG A 115
ILE A 112
LEU A  48
GLU A  96
 None
 1.07A 2ya7D-4b9yA:
undetectable		 2ya7D-4b9yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bp8 OLIGOPEPTIDASE B

(Trypanosoma
brucei) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 ARG A 213
ILE A 255
LEU A 279
GLU A 264
 None
 1.07A 2ya7D-4bp8A:
9.1		 2ya7D-4bp8A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7w HEMAGGLUTININ-ESTERA
SE

(Murine
coronavirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 ARG A 265
ILE A 206
LEU A 292
GLU A 140
 None
 1.05A 2ya7D-4c7wA:
undetectable		 2ya7D-4c7wA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ASP A 605
ILE A 487
LEU A 508
GLU A 594
 None
 1.04A 2ya7D-4cakA:
7.5		 2ya7D-4cakA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ASP A 605
ILE A 487
LEU A 508
TYR A 645
 None
 0.96A 2ya7D-4cakA:
7.5		 2ya7D-4cakA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvu BETA-MANNOSIDASE

(Trichoderma
harzianum) 		PF00703
(Glyco_hydro_2) 		4 ARG A 161
ILE A  82
LEU A  61
TYR A  89
 None
 0.97A 2ya7D-4cvuA:
undetectable		 2ya7D-4cvuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gf8 PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Vibrio cholerae) 		PF00496
(SBP_bac_5) 		4 ASP A 283
ILE A 284
LEU A 371
TYR A 321
 None
 0.99A 2ya7D-4gf8A:
undetectable		 2ya7D-4gf8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy3 PHOSPHOGLYCERATE
OXIDOREDUCTASE

(Rhizobium etli) 		PF02826
(2-Hacid_dh_C) 		4 ARG A  27
ILE A  10
LEU A  47
GLU A  14
 None
 1.04A 2ya7D-4hy3A:
undetectable		 2ya7D-4hy3A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j6c CYTOCHROME P450
MONOOXYGENASE

(Nocardia
farcinica) 		PF00067
(p450) 		4 ASP A 302
ILE A 303
LEU A 305
GLU A 314
 None
 1.06A 2ya7D-4j6cA:
undetectable		 2ya7D-4j6cA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ls9 DHH FAMILY PROTEIN

(Mycolicibacterium
smegmatis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 ARG A 190
ASP A 271
ILE A 272
LEU A 229
 None
 0.92A 2ya7D-4ls9A:
undetectable		 2ya7D-4ls9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mph D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF02557
(VanY) 		5 ARG A 127
ASP A 167
ILE A 220
LEU A 190
TYR A 215
 None
ZN  A 400 ( 1.8A)
None
None
None
 1.41A 2ya7D-4mphA:
undetectable		 2ya7D-4mphA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt6 RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 9

(Rattus
norvegicus) 		PF00018
(SH3_1)
PF00169
(PH)
PF00621
(RhoGEF) 		4 ASP A 374
ILE A 373
LEU A 401
GLU A 430
 None
 1.05A 2ya7D-4mt6A:
undetectable		 2ya7D-4mt6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7y MINICHROMOSOME
MAINTENANCE PROTEIN
MCM, CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus;
Sulfolobus
solfataricus) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ARG A1317
ASP A1321
ILE A1322
GLU A1933
 None
 1.02A 2ya7D-4r7yA:
undetectable		 2ya7D-4r7yA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoo LIPOTEICHOIC ACID
SYNTHASE

(Listeria
monocytogenes) 		PF00884
(Sulfatase) 		4 ILE A 341
LEU A 540
GLU A 315
TYR A 259
 None
 0.88A 2ya7D-4uooA:
undetectable		 2ya7D-4uooA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8l ENDO-1,4-BETA-XYLANA
SE C

(Paenibacillus
barcinonensis) 		PF00331
(Glyco_hydro_10) 		4 ARG A 445
ASP A 507
ILE A 509
LEU A 545
 None
CA  A1101 (-2.2A)
None
None
 0.88A 2ya7D-4w8lA:
undetectable		 2ya7D-4w8lA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 2
ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Drosophila
melanogaster) 		PF04084
(ORC2)
PF07034
(ORC3_N) 		4 ARG C 180
ASP B 416
ILE B 418
LEU B 454
 None
 1.02A 2ya7D-4xgcC:
undetectable		 2ya7D-4xgcC:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7l TYPE VI SECRETION
PROTEIN ICMF

(Escherichia
coli) 		PF06744
(IcmF_C) 		4 ARG A 938
ILE A 965
LEU A1096
GLU A1088
 None
 0.89A 2ya7D-4y7lA:
undetectable		 2ya7D-4y7lA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8t AVRRXO1-ORF1
AVRRXO1-ORF2

(Xanthomonas
oryzae) 		no annotation 4 ASP B  68
ILE B  69
LEU B  60
GLU A 251
 None
 0.70A 2ya7D-4z8tB:
undetectable		 2ya7D-4z8tB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awn HEAVY CHAIN OF
3BC176 FAB

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ASP H  52
ILE H  51
LEU H  78
TYR H  27
 None
 1.05A 2ya7D-5awnH:
undetectable		 2ya7D-5awnH:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Bordetella
bronchiseptica) 		PF01522
(Polysacc_deac_1) 		4 ASP A  95
ILE A  93
LEU A 285
GLU A 180
 None
None
None
EDO  A 408 (-3.7A)
 0.98A 2ya7D-5bu6A:
undetectable		 2ya7D-5bu6A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5civ SIBLING BACTERIOCIN

(Paenibacillus
dendritiformis) 		PF08020
(DUF1706) 		4 ASP A 131
ILE A 130
LEU A  23
GLU A 123
 None
 1.06A 2ya7D-5civA:
undetectable		 2ya7D-5civA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 ASP A 684
ILE A 686
LEU A 675
GLU A 764
 None
 0.90A 2ya7D-5eawA:
undetectable		 2ya7D-5eawA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32

(Mycobacterium
marinum) 		PF00501
(AMP-binding) 		4 ASP A 568
ILE A 566
LEU A 587
GLU A 562
 None
 1.04A 2ya7D-5ey9A:
undetectable		 2ya7D-5ey9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9o CH235.9 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ASP H  52
ILE H  51
LEU H  79
TYR H  27
 None
 1.07A 2ya7D-5f9oH:
undetectable		 2ya7D-5f9oH:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ftt NETRIN RECEPTOR
UNC5D

(Rattus
norvegicus) 		PF00090
(TSP_1)
PF07679
(I-set) 		4 ASP A 199
ILE A 198
LEU A 214
GLU A 190
 None
 0.95A 2ya7D-5fttA:
undetectable		 2ya7D-5fttA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h68 CHROMOSOME PARTITION
PROTEIN SMC

(Geobacillus
stearothermophilus) 		PF02463
(SMC_N) 		4 ASP A   7
ILE A  82
LEU A   3
GLU A  97
 None
 0.99A 2ya7D-5h68A:
undetectable		 2ya7D-5h68A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hif RECONSTRUCTED
LACTONASE ANCESTOR,
ANC1-MPH

(synthetic
construct) 		PF00753
(Lactamase_B) 		4 ASP A 221
ILE A 223
LEU A 269
TYR A  67
 ZN  A 401 ( 2.4A)
None
None
None
 1.04A 2ya7D-5hifA:
undetectable		 2ya7D-5hifA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8r PROTOCADHERIN
GAMMA-B3

(Homo sapiens) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 ASP A  58
ILE A  60
LEU A  74
GLU A  64
 None
 1.04A 2ya7D-5k8rA:
undetectable		 2ya7D-5k8rA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhi 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 6

(Homo sapiens) 		PF01399
(PCI)
PF10602
(RPN7) 		4 ARG Y 101
ASP Y 139
LEU Y 180
GLU Y 170
 None
 0.79A 2ya7D-5vhiY:
undetectable		 2ya7D-5vhiY:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 ASP A  66
ILE A  68
LEU A  50
GLU A  93
 None
 1.06A 2ya7D-5y7oA:
undetectable		 2ya7D-5y7oA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zdh TYPE II SECRETION
SYSTEM PROTEIN D

(Escherichia
coli) 		no annotation 4 ARG A 111
ILE A 143
LEU A 122
GLU A 117
 None
 1.02A 2ya7D-5zdhA:
undetectable		 2ya7D-5zdhA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bni LYSINE--TRNA LIGASE

(Cryptosporidium
parvum) 		no annotation 4 ARG A 107
ASP A 117
ILE A 118
LEU A  76
 None
 0.73A 2ya7D-6bniA:
undetectable		 2ya7D-6bniA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 4 ASP A 280
ILE A 205
LEU A 191
GLU A 218
 None
 0.95A 2ya7D-6bogA:
undetectable		 2ya7D-6bogA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cdd NPL4 ZINC FINGER

(Chaetomium
thermophilum) 		no annotation 4 ARG A 276
ILE A 345
LEU A 286
GLU A 309
 None
 1.06A 2ya7D-6cddA:
undetectable		 2ya7D-6cddA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae) 		no annotation 4 ARG A 874
ASP A 636
ILE A 638
LEU A 628
 None
 1.05A 2ya7D-6fikA:
undetectable		 2ya7D-6fikA:
12.74