SIMILAR PATTERNS OF AMINO ACIDS FOR 2YA7_A_ZMRA1776

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		6 ARG A  35
ASP A  51
ASP A  96
ARG A 245
ARG A 314
TYR A 342
 DAN  A 700 (-3.0A)
None
DAN  A 700 (-3.3A)
DAN  A 700 (-2.8A)
DAN  A 700 (-3.0A)
DAN  A 700 (-3.5A)
 0.97A 2ya7A-1ms8A:
40.0		 2ya7A-1ms8A:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mz5 SIALIDASE

(Trypanosoma
rangeli) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		7 ARG A  36
ILE A  37
ASP A  52
ASP A  97
ARG A 246
ARG A 315
TYR A 343
 None
 0.47A 2ya7A-1mz5A:
40.3		 2ya7A-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mz5 SIALIDASE

(Trypanosoma
rangeli) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		6 ARG A  36
ILE A  37
ASP A  52
ILE A  64
ARG A 315
TYR A 343
 None
 1.40A 2ya7A-1mz5A:
40.3		 2ya7A-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8o BACTERIAL SIALIDASE

(Micromonospora
viridifaciens) 		PF00754
(F5_F8_type_C)
PF10633
(NPCBM_assoc)
PF13088
(BNR_2) 		7 ARG A  68
ILE A  69
ASP A  85
ASP A 131
ARG A 276
ARG A 342
TYR A 370
 CIT  A1649 ( 2.6A)
None
None
GOL  A1650 (-2.7A)
CIT  A1649 ( 2.7A)
CIT  A1649 ( 2.9A)
CIT  A1649 (-4.5A)
 0.37A 2ya7A-1w8oA:
47.5		 2ya7A-1w8oA:
24.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF13088
(BNR_2) 		5 ARG A 266
ILE A 267
ASP A 283
ILE A 297
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
None
SIA  A1692 (-3.1A)
 1.40A 2ya7A-2bf6A:
57.0		 2ya7A-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF13088
(BNR_2) 		10 ARG A 266
ILE A 267
ASP A 283
ILE A 327
ASP A 328
TYR A 485
GLN A 493
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.35A 2ya7A-2bf6A:
57.0		 2ya7A-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF13088
(BNR_2) 		5 ARG A 285
ILE A 267
ASP A 328
TYR A 485
GLN A 493
 SIA  A1692 (-3.6A)
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
 1.22A 2ya7A-2bf6A:
57.0		 2ya7A-2bf6A:
43.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f28 SIALIDASE 2

(Homo sapiens) 		PF13088
(BNR_2) 		6 ARG A  21
ILE A  22
TYR A 179
ARG A 237
ARG A 304
TYR A 334
 None
 0.41A 2ya7A-2f28A:
42.9		 2ya7A-2f28A:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		11 ARG A 347
ILE A 348
ASP A 364
ILE A 416
ASP A 417
ASP A 434
TYR A 590
GLN A 602
ARG A 663
ARG A 721
TYR A 752
 None
 0.21A 2ya7A-2w20A:
68.2		 2ya7A-2w20A:
94.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		5 ARG A 366
ASP A 417
PHE A 443
TYR A 590
GLN A 602
 None
 1.36A 2ya7A-2w20A:
68.2		 2ya7A-2w20A:
94.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		5 ARG A 366
ILE A 348
ASP A 417
TYR A 590
GLN A 602
 None
 1.23A 2ya7A-2w20A:
68.2		 2ya7A-2w20A:
94.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		7 ASP A 364
ILE A 416
ASP A 417
ASP A 434
PHE A 443
TYR A 590
GLN A 602
 None
 0.70A 2ya7A-2w20A:
68.2		 2ya7A-2w20A:
94.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w38 SIALIDASE

(Pseudomonas
aeruginosa) 		PF13088
(BNR_2) 		5 ASP A  79
TYR A 146
ARG A 198
ARG A 260
TYR A 297
 None
 0.72A 2ya7A-2w38A:
33.2		 2ya7A-2w38A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzi EXTRACELLULAR
SIALIDASE/NEURAMINID
ASE, PUTATIVE

(Aspergillus
fumigatus) 		PF13088
(BNR_2) 		5 ARG A  59
ILE A  60
ARG A 265
ARG A 322
TYR A 358
 KDM  A 500 (-2.7A)
None
KDM  A 500 (-2.7A)
KDM  A 500 ( 3.0A)
KDM  A 500 (-4.5A)
 0.32A 2ya7A-2xziA:
41.5		 2ya7A-2xziA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		5 ILE A 238
TYR A 293
GLN A 513
ARG A 567
TYR A 604
 None
 1.30A 2ya7A-3eb7A:
undetectable		 2ya7A-3eb7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sil SIALIDASE

(Salmonella
enterica) 		PF13859
(BNR_3) 		7 ARG A  37
ILE A  38
ASP A  54
ASP A 100
ARG A 246
ARG A 309
TYR A 342
 PO4  A 499 (-2.7A)
None
None
GOL  A 403 (-3.4A)
PO4  A 499 (-2.7A)
PO4  A 499 (-3.0A)
PO4  A 499 (-4.6A)
 0.43A 2ya7A-3silA:
40.4		 2ya7A-3silA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbw SIALIDASE
(NEURAMINIDASE)

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		7 ARG A 204
ILE A 205
ASP A 221
ASP A 272
ARG A 415
ARG A 479
TYR A 510
 None
 0.48A 2ya7A-4bbwA:
45.7		 2ya7A-4bbwA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e0t CYCLIC DIPEPTIDE
N-PRENYLTRANSFERASE

(Aspergillus
fumigatus) 		PF11991
(Trp_DMAT) 		5 ARG A 284
ASP A 276
ASP A 210
TYR A 431
GLN A 122
 None
None
None
CL  A 606 (-4.9A)
None
 1.35A 2ya7A-4e0tA:
undetectable		 2ya7A-4e0tA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj6 GLYCOSIDE HYDROLASE
FAMILY 33, CANDIDATE
SIALIDASE

(Parabacteroides
distasonis) 		PF13859
(BNR_3)
PF14873
(BNR_assoc_N) 		7 ARG A 200
ILE A 201
ASP A 217
ASP A 268
ARG A 411
ARG A 475
TYR A 506
 PO4  A 607 ( 2.6A)
None
None
None
PO4  A 607 (-2.7A)
PO4  A 607 (-2.8A)
PO4  A 607 (-4.6A)
 0.32A 2ya7A-4fj6A:
46.2		 2ya7A-4fj6A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzh HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		6 ARG A 174
ILE A 175
TYR A 317
ARG A 416
ARG A 498
TYR A 526
 None
 0.94A 2ya7A-4fzhA:
10.4		 2ya7A-4fzhA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG

(Anguilla
japonica) 		PF00061
(Lipocalin) 		5 ILE A  24
ASP A  81
GLN A  57
ARG A 112
TYR A  99
 None
None
BLR  A 200 (-2.7A)
BLR  A 200 (-3.6A)
BLR  A 200 ( 4.4A)
 1.44A 2ya7A-4i3cA:
2.0		 2ya7A-4i3cA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG

(Anguilla
japonica) 		PF00061
(Lipocalin) 		5 ILE A  24
ASP A  81
PHE A  17
GLN A  57
ARG A 112
 None
None
BLR  A 200 (-3.6A)
BLR  A 200 (-2.7A)
BLR  A 200 (-3.6A)
 1.19A 2ya7A-4i3cA:
2.0		 2ya7A-4i3cA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jf7 HEMAGGLUTININ-NEURAM
INIDASE

(Mammalian
rubulavirus 5) 		no annotation 6 ARG D 163
ILE D 164
TYR D 306
ARG D 405
ARG D 495
TYR D 523
 SO4  D 608 ( 4.1A)
None
None
SO4  D 608 (-2.6A)
SO4  D 608 (-3.3A)
None
 0.70A 2ya7A-4jf7D:
26.0		 2ya7A-4jf7D:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)

(Streptococcus
parasanguinis) 		PF08759
(GT-D) 		5 ASP A 252
ILE A 255
TYR A 263
GLN A 264
ARG A 270
 None
 1.36A 2ya7A-4phsA:
undetectable		 2ya7A-4phsA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6k BNR/ASP-BOX REPEAT
PROTEIN

(Bacteroides
caccae) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		7 ARG A 220
ILE A 221
ASP A 237
ASP A 288
ARG A 431
ARG A 495
TYR A 526
 EDO  A 604 (-4.0A)
None
None
EDO  A 607 (-3.1A)
None
None
None
 0.33A 2ya7A-4q6kA:
45.9		 2ya7A-4q6kA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sli INTRAMOLECULAR
TRANS-SIALIDASE

(Macrobdella
decora) 		PF02973
(Sialidase)
PF13088
(BNR_2) 		5 ARG A 293
ILE A 294
ASP A 310
ILE A 323
ARG A 673
 CNP  A 760 (-3.0A)
CNP  A 760 (-4.5A)
None
None
CNP  A 760 (-3.0A)
 1.28A 2ya7A-4sliA:
46.1		 2ya7A-4sliA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sli INTRAMOLECULAR
TRANS-SIALIDASE

(Macrobdella
decora) 		PF02973
(Sialidase)
PF13088
(BNR_2) 		10 ARG A 293
ILE A 294
ASP A 310
ILE A 374
ASP A 375
ASP A 392
TYR A 561
ARG A 611
ARG A 673
TYR A 713
 CNP  A 760 (-3.0A)
CNP  A 760 (-4.5A)
None
CNP  A 760 ( 4.4A)
CNP  A 760 (-2.8A)
CNP  A 760 (-4.4A)
None
CNP  A 760 (-3.0A)
CNP  A 760 (-3.0A)
CNP  A 760 (-4.0A)
 0.42A 2ya7A-4sliA:
46.1		 2ya7A-4sliA:
25.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		5 ARG A 257
ILE A 258
ASP A 274
ILE A 287
ARG A 637
 3XR  A 802 (-3.0A)
None
None
None
3XR  A 802 (-3.0A)
 1.46A 2ya7A-4x6kA:
40.9		 2ya7A-4x6kA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		10 ARG A 257
ILE A 258
ASP A 274
ILE A 338
ASP A 339
ASP A 356
TYR A 525
ARG A 575
ARG A 637
TYR A 677
 3XR  A 802 (-3.0A)
None
None
3XR  A 802 (-4.2A)
3XR  A 802 (-2.8A)
3XR  A 802 (-4.6A)
None
3XR  A 802 (-2.6A)
3XR  A 802 (-3.0A)
3XR  A 802 (-4.2A)
 0.36A 2ya7A-4x6kA:
40.9		 2ya7A-4x6kA:
31.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhb SIALIDASE B

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		5 ARG A 245
ILE A 246
ASP A 262
ILE A 275
ARG A 619
 NHE  A 702 (-2.7A)
None
None
None
NHE  A 702 (-2.9A)
 1.46A 2ya7A-4xhbA:
40.7		 2ya7A-4xhbA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhb SIALIDASE B

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		10 ARG A 245
ILE A 246
ASP A 262
ILE A 326
ASP A 327
ASP A 344
TYR A 509
ARG A 557
ARG A 619
TYR A 653
 NHE  A 702 (-2.7A)
None
None
NHE  A 702 ( 4.8A)
NHE  A 702 (-3.6A)
None
None
NHE  A 702 (-2.8A)
NHE  A 702 (-2.9A)
NHE  A 702 (-4.8A)
 0.34A 2ya7A-4xhbA:
40.7		 2ya7A-4xhbA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		5 ARG A 290
ASP A 307
ILE A 371
ASP A 388
PHE A 316
 G39  A 801 (-2.6A)
None
None
G39  A 801 ( 4.8A)
GOL  A 802 (-4.9A)
 0.83A 2ya7A-4yw5A:
42.9		 2ya7A-4yw5A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		6 ARG A 290
ILE A 291
ASP A 307
ILE A 320
ARG A 662
TYR A 695
 G39  A 801 (-2.6A)
None
None
None
G39  A 801 (-2.9A)
G39  A 801 (-4.4A)
 1.32A 2ya7A-4yw5A:
42.9		 2ya7A-4yw5A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		10 ARG A 290
ILE A 291
ASP A 307
ILE A 371
ASP A 372
ASP A 388
TYR A 553
ARG A 600
ARG A 662
TYR A 695
 G39  A 801 (-2.6A)
None
None
None
G39  A 801 (-2.6A)
G39  A 801 ( 4.8A)
None
G39  A 801 (-2.9A)
G39  A 801 (-2.9A)
G39  A 801 (-4.4A)
 0.38A 2ya7A-4yw5A:
42.9		 2ya7A-4yw5A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2d HN PROTEIN

(Mumps
rubulavirus) 		PF00423
(HN) 		6 ARG A 180
ILE A 181
TYR A 323
ARG A 422
ARG A 512
TYR A 540
 SLT  A 606 (-2.6A)
None
SLT  A 606 (-4.6A)
SLT  A 606 (-3.0A)
SLT  A 606 (-2.8A)
SLT  A 606 (-4.7A)
 0.60A 2ya7A-5b2dA:
7.9		 2ya7A-5b2dA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dl5 MEMBRANE PROTEIN

(Acinetobacter
baumannii) 		PF03573
(OprD) 		5 ILE A 312
ILE A 301
ASP A 310
PHE A 298
TYR A 397
 None
 1.34A 2ya7A-5dl5A:
undetectable		 2ya7A-5dl5A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byw GOXA

(Pseudoalteromonas
luteoviolacea) 		no annotation 5 ARG B 404
ILE B 365
ASP B 360
TYR B  45
TYR B 807
 None
None
MG  B 901 (-2.8A)
None
None
 1.25A 2ya7A-6bywB:
undetectable		 2ya7A-6bywB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eks SIALIDASE

(Vibrio cholerae) 		no annotation 6 ARG A 250
ILE A 251
ASP A 318
ARG A 661
ARG A 738
TYR A 766
 G39  A 908 (-2.8A)
G39  A 908 (-4.7A)
G39  A 908 ( 4.2A)
G39  A 908 (-2.8A)
G39  A 908 (-3.0A)
G39  A 908 (-4.6A)
 0.84A 2ya7A-6eksA:
43.2		 2ya7A-6eksA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1akc ASPARTATE
AMINOTRANSFERASE

(Gallus gallus) 		PF00155
(Aminotran_1_2) 		4 ASP A 249
ILE A 244
LEU A  88
GLU A  93
 None
 1.08A 2ya7A-1akcA:
0.0		 2ya7A-1akcA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpt CYTOCHROME P450-TERP

(Pseudomonas sp.) 		PF00067
(p450) 		4 ASP A 359
ILE A 360
LEU A 299
GLU A 288
 None
 1.02A 2ya7A-1cptA:
undetectable		 2ya7A-1cptA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dd5 RIBOSOME RECYCLING
FACTOR

(Thermotoga
maritima) 		PF01765
(RRF) 		4 ARG A 129
ILE A  20
LEU A  24
GLU A 119
 None
 0.97A 2ya7A-1dd5A:
0.0		 2ya7A-1dd5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxl DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pisum sativum) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 277
ILE A  51
LEU A  98
TYR A  19
 FAD  A 480 (-3.5A)
None
None
None
 1.00A 2ya7A-1dxlA:
0.0		 2ya7A-1dxlA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN

(Escherichia
virus T4) 		PF13597
(NRDD) 		4 ASP A 325
ILE A 322
LEU A 317
GLU A 343
 None
 0.87A 2ya7A-1h79A:
0.0		 2ya7A-1h79A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv5 STROMELYSIN 3

(Mus musculus) 		PF00413
(Peptidase_M10) 		4 ARG A 191
ASP A 158
ILE A 159
LEU A 138
 None
CPS  A5006 ( 4.9A)
None
None
 0.96A 2ya7A-1hv5A:
0.0		 2ya7A-1hv5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv8 PUTATIVE
ATP-DEPENDENT RNA
HELICASE MJ0669

(Methanocaldococcus
jannaschii) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 ASP A 154
ILE A  79
LEU A  65
GLU A  93
 None
None
None
SO4  A 803 ( 4.7A)
 1.06A 2ya7A-1hv8A:
undetectable		 2ya7A-1hv8A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8f ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN

(Homo sapiens) 		PF08603
(CAP_C) 		4 ASP A 383
ILE A 363
LEU A 361
GLU A 343
 None
 0.92A 2ya7A-1k8fA:
undetectable		 2ya7A-1k8fA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 266
ILE A  49
LEU A  98
TYR A  18
 FAD  A 459 ( 3.9A)
None
None
None
 1.04A 2ya7A-1lvlA:
undetectable		 2ya7A-1lvlA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mn6 POLYKETIDE SYNTHASE
IV

(Streptomyces
venezuelae) 		PF00975
(Thioesterase) 		4 ARG A 163
ILE A 172
LEU A 174
GLU A 156
 None
 1.07A 2ya7A-1mn6A:
undetectable		 2ya7A-1mn6A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nio B-LUFFIN

(Luffa
aegyptiaca) 		PF00161
(RIP) 		4 ARG A 163
ILE A 154
LEU A 139
TYR A 107
 None
 1.05A 2ya7A-1nioA:
undetectable		 2ya7A-1nioA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4z BETA-AGARASE B

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		4 ASP A 103
ILE A 147
LEU A 129
TYR A  86
 None
 1.05A 2ya7A-1o4zA:
1.8		 2ya7A-1o4zA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oz9 HYPOTHETICAL PROTEIN
AQ_1354

(Aquifex
aeolicus) 		PF02130
(UPF0054) 		4 ASP A  23
ILE A  25
LEU A  15
GLU A 106
 None
 1.02A 2ya7A-1oz9A:
undetectable		 2ya7A-1oz9A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p9e METHYL PARATHION
HYDROLASE

(Pseudomonas sp.
WBC-3) 		PF00753
(Lactamase_B) 		4 ASP A 255
ILE A 257
LEU A 303
TYR A 100
 ZN  A 401 ( 2.2A)
None
None
None
 1.08A 2ya7A-1p9eA:
undetectable		 2ya7A-1p9eA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ty2 PUTATIVE EXOTOXIN
(SUPERANTIGEN)

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 ASP A 135
ILE A 138
LEU A 142
TYR A 175
 None
 1.04A 2ya7A-1ty2A:
undetectable		 2ya7A-1ty2A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vph HYPOTHETICAL PROTEIN
SSO2532

(Sulfolobus
solfataricus) 		PF01894
(UPF0047) 		4 ASP A  62
ILE A  63
LEU A  18
GLU A  54
 None
 0.87A 2ya7A-1vphA:
undetectable		 2ya7A-1vphA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI

(Escherichia
coli) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ASP A 291
ILE A 290
LEU A 340
GLU A 283
 None
 1.03A 2ya7A-1we5A:
undetectable		 2ya7A-1we5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg8 HYPOTHETICAL PROTEIN
SA0798

(Staphylococcus
aureus) 		PF07315
(DUF1462) 		4 ASP A  45
ILE A  44
LEU A  53
GLU A  65
 None
 0.85A 2ya7A-1xg8A:
undetectable		 2ya7A-1xg8A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xu1 TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER
13

(Mus musculus) 		PF00229
(TNF) 		4 ASP A 214
ILE A 216
LEU A 156
GLU A 182
 None
 0.95A 2ya7A-1xu1A:
undetectable		 2ya7A-1xu1A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a33 HYPOTHETICAL PROTEIN

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		4 ASP A 111
ILE A  16
LEU A  41
GLU A 189
 None
 1.02A 2ya7A-2a33A:
undetectable		 2ya7A-2a33A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaf ARGININE DEIMINASE

(Pseudomonas
aeruginosa) 		PF02274
(Amidinotransf) 		4 ARG A  63
ASP A  68
ILE A 411
LEU A   8
 None
 1.01A 2ya7A-2aafA:
undetectable		 2ya7A-2aafA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC

(Homo sapiens) 		PF01063
(Aminotran_4) 		4 ASP A 340
ILE A 350
LEU A 318
GLU A 354
 None
 0.95A 2ya7A-2abjA:
1.3		 2ya7A-2abjA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axp HYPOTHETICAL PROTEIN
BSU20280

(Bacillus
subtilis) 		PF02223
(Thymidylate_kin) 		4 ASP A  10
ILE A 108
LEU A 129
GLU A 121
 None
 0.98A 2ya7A-2axpA:
undetectable		 2ya7A-2axpA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ASP A1099
ILE A1100
LEU A1058
TYR A  58
 None
 1.04A 2ya7A-2b5mA:
12.0		 2ya7A-2b5mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg8 DIHYDRONEOPTERIN
ALDOLASE
6-HYDROXYMETHYL-7,8-
DIHYDROPTERIN
SYNTHASE

(Streptococcus
pneumoniae) 		PF01288
(HPPK)
PF02152
(FolB) 		4 ARG A 238
ILE A 124
LEU A 187
GLU A 195
 None
 1.06A 2ya7A-2cg8A:
undetectable		 2ya7A-2cg8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cqk C-MPL BINDING
PROTEIN

(Homo sapiens) 		PF05383
(La) 		4 ASP A  99
ILE A 103
LEU A  53
GLU A 105
 None
 1.03A 2ya7A-2cqkA:
undetectable		 2ya7A-2cqkA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfk COLLYBISTIN II

(Rattus
norvegicus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ASP A 314
ILE A 313
LEU A 341
GLU A 370
 None
 1.01A 2ya7A-2dfkA:
undetectable		 2ya7A-2dfkA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 ARG A1067
ILE A 529
LEU A 511
GLU A 487
 None
 0.86A 2ya7A-2eyqA:
undetectable		 2ya7A-2eyqA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fef HYPOTHETICAL PROTEIN
PA2201

(Pseudomonas
aeruginosa) 		PF08929
(DUF1911) 		4 ASP A  92
ILE A  91
LEU A 281
TYR A 230
 None
 1.04A 2ya7A-2fefA:
undetectable		 2ya7A-2fefA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ija ARYLAMINE
N-ACETYLTRANSFERASE
1

(Homo sapiens) 		PF00797
(Acetyltransf_2) 		4 ASP A 251
ILE A 253
LEU A 181
TYR A 129
 None
 1.07A 2ya7A-2ijaA:
undetectable		 2ya7A-2ijaA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nef NEGATIVE FACTOR
(F-PROTEIN)

(Human
immunodeficiency
virus 1) 		PF00469
(F-protein) 		4 ASP A 111
ILE A 114
LEU A  87
TYR A 143
 None
 1.07A 2ya7A-2nefA:
undetectable		 2ya7A-2nefA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqa LUFFACULIN 1

(Luffa
acutangula) 		PF00161
(RIP) 		4 ARG A 162
ILE A 153
LEU A 138
TYR A 106
 None
 1.07A 2ya7A-2oqaA:
undetectable		 2ya7A-2oqaA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfv EXOCYST COMPLEX
COMPONENT EXO70

(Saccharomyces
cerevisiae) 		PF03081
(Exo70) 		4 ASP A 113
ILE A 114
LEU A 134
GLU A  80
 None
 1.08A 2ya7A-2pfvA:
undetectable		 2ya7A-2pfvA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkh HISTIDINE
UTILIZATION
REPRESSOR

(Pseudomonas
syringae group
genomosp. 3) 		PF07702
(UTRA) 		5 ARG A 126
ASP A 156
ILE A 235
LEU A 207
GLU A 200
 None
None
None
None
EDO  A1014 (-4.2A)
 1.44A 2ya7A-2pkhA:
1.2		 2ya7A-2pkhA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Cupriavidus
pinatubonensis) 		PF02627
(CMD) 		4 ASP A 160
ILE A 161
LEU A 148
GLU A  72
 None
 0.98A 2ya7A-2prrA:
undetectable		 2ya7A-2prrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qae DIHYDROLIPOYL
DEHYDROGENASE

(Trypanosoma
cruzi) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ARG A 274
ILE A  47
LEU A  95
TYR A  15
 FAD  A 480 (-3.9A)
None
None
None
 1.07A 2ya7A-2qaeA:
undetectable		 2ya7A-2qaeA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT

(Pseudomonas
putida) 		PF00355
(Rieske) 		4 ASP A 101
ILE A 100
LEU A  28
GLU A  24
 None
 0.97A 2ya7A-2qpzA:
undetectable		 2ya7A-2qpzA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qxx DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE

(Mycobacterium
tuberculosis) 		PF00692
(dUTPase) 		4 ARG A 188
ASP A  52
ILE A  51
LEU A  60
 None
 0.96A 2ya7A-2qxxA:
undetectable		 2ya7A-2qxxA:
17.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		5 ASP A 372
ILE A 442
LEU A 598
GLU A 647
TYR A 695
 None
 0.77A 2ya7A-2w20A:
68.2		 2ya7A-2w20A:
94.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xj9 MIPZ

(Caulobacter
vibrioides) 		PF09140
(MipZ) 		4 ARG A 225
ILE A  21
LEU A 184
GLU A 256
 AGS  A1272 (-3.6A)
None
None
None
 1.07A 2ya7A-2xj9A:
undetectable		 2ya7A-2xj9A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 ARG A 165
ILE A 169
LEU A 120
GLU A 187
 None
 1.08A 2ya7A-3b02A:
undetectable		 2ya7A-3b02A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1r RIBOKINASE, PUTATIVE

(Burkholderia
thailandensis) 		PF00294
(PfkB) 		4 ARG A 231
ILE A 218
LEU A 259
GLU A 235
 None
 1.01A 2ya7A-3b1rA:
undetectable		 2ya7A-3b1rA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjx HALOCARBOXYLIC ACID
DEHALOGENASE DEHI

(Pseudomonas
putida) 		PF10778
(DehI) 		4 ASP A  97
ILE A 100
LEU A 283
GLU A  88
 None
 0.94A 2ya7A-3bjxA:
undetectable		 2ya7A-3bjxA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c87 ENTEROCHELIN
ESTERASE

(Shigella
flexneri) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 ASP A 233
ILE A 232
LEU A 258
GLU A 243
 None
 1.03A 2ya7A-3c87A:
undetectable		 2ya7A-3c87A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8t FUMARATE LYASE

(Chelativorans
sp. BNC1) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 ASP A 264
ILE A 265
LEU A 359
GLU A 275
 None
 0.97A 2ya7A-3c8tA:
undetectable		 2ya7A-3c8tA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cer POSSIBLE
EXOPOLYPHOSPHATASE-L
IKE PROTEIN

(Bifidobacterium
longum) 		PF02541
(Ppx-GppA) 		4 ASP A 335
ILE A 332
LEU A 328
GLU A 120
 None
None
SO4  A 346 (-4.2A)
None
 1.08A 2ya7A-3cerA:
undetectable		 2ya7A-3cerA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cg3 UPF0100 PROTEIN
PH0151

(Pyrococcus
horikoshii) 		PF13531
(SBP_bac_11) 		4 ARG A 206
ILE A 117
LEU A 245
TYR A 172
 None
 1.03A 2ya7A-3cg3A:
undetectable		 2ya7A-3cg3A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN
RESPIRATORY NITRATE
REDUCTASE 1 BETA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF13247
(Fer4_11)
PF14710
(Nitr_red_alph_N)
PF14711
(Nitr_red_bet_C) 		4 ARG A  90
ILE B  17
LEU A 290
GLU A 269
 None
F3S  B 802 (-4.4A)
None
None
 1.03A 2ya7A-3egwA:
undetectable		 2ya7A-3egwA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpn GEOBACILLUS
STEAROTHERMOPHILUS
UVRA INTERACTION
DOMAIN

(Geobacillus
stearothermophilus) 		no annotation 4 ASP A 189
ILE A 190
LEU A 192
GLU A 167
 None
 0.92A 2ya7A-3fpnA:
undetectable		 2ya7A-3fpnA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g4g CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		4 ASP A 540
ILE A 539
LEU A 565
GLU A 570
 None
 1.08A 2ya7A-3g4gA:
undetectable		 2ya7A-3g4gA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqj CELL INHIBITING
FACTOR (CIF)

(Photorhabdus
laumondii) 		PF16374
(CIF) 		4 ASP A 255
ILE A 250
LEU A 179
GLU A 264
 None
 0.99A 2ya7A-3gqjA:
undetectable		 2ya7A-3gqjA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwq D-SERINE DEAMINASE

(Paraburkholderia
xenovorans) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 ASP A 389
ILE A 391
LEU A 377
GLU A 363
 None
 0.91A 2ya7A-3gwqA:
undetectable		 2ya7A-3gwqA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrl ENDONUCLEASE-LIKE
PROTEIN

(Neisseria
gonorrhoeae) 		PF04480
(DUF559) 		4 ASP A  59
ILE A  68
LEU A  90
TYR A  82
 None
 1.07A 2ya7A-3hrlA:
undetectable		 2ya7A-3hrlA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbe TCR 21.3 ALPHA CHAIN

(Mus musculus) 		PF07686
(V-set)
PF09291
(DUF1968) 		4 ASP C  93
ILE C  91
LEU C  79
GLU C  97
 None
 1.04A 2ya7A-3mbeC:
undetectable		 2ya7A-3mbeC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mga ENTEROCHELIN
ESTERASE

(Salmonella
enterica) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 ASP A 238
ILE A 237
LEU A 263
GLU A 248
 None
 1.06A 2ya7A-3mgaA:
undetectable		 2ya7A-3mgaA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nmz APC VARIANT PROTEIN

(Homo sapiens) 		PF00514
(Arm) 		4 ASP A 605
ILE A 606
LEU A 592
GLU A 574
 None
 1.05A 2ya7A-3nmzA:
undetectable		 2ya7A-3nmzA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvs 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Vibrio cholerae) 		PF00275
(EPSP_synthase) 		4 ASP A 112
ILE A 153
LEU A 115
GLU A 141
 None
 1.00A 2ya7A-3nvsA:
undetectable		 2ya7A-3nvsA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pei CYTOSOL
AMINOPEPTIDASE

(Francisella
tularensis) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 ASP A 101
ILE A 100
LEU A 144
GLU A  14
 PEG  A 492 (-4.4A)
None
None
None
 1.00A 2ya7A-3peiA:
undetectable		 2ya7A-3peiA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vcn MANNONATE
DEHYDRATASE

(Caulobacter
vibrioides) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ARG A 343
ILE A 147
LEU A 202
GLU A 135
 GOL  A 506 ( 4.9A)
None
None
None
 0.84A 2ya7A-3vcnA:
undetectable		 2ya7A-3vcnA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL

(Arabidopsis
thaliana) 		PF00498
(FHA) 		4 ASP A 115
ILE A 117
LEU A  19
TYR A  67
 None
 0.97A 2ya7A-3vpyA:
undetectable		 2ya7A-3vpyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2

(Saccharomyces
cerevisiae) 		PF16834
(CSM2) 		4 ASP B  41
ILE B 116
LEU B  80
GLU B 120
 None
 1.04A 2ya7A-3vu9B:
undetectable		 2ya7A-3vu9B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		4 ASP A 395
ILE A 394
LEU A  32
GLU A 390
 None
 1.08A 2ya7A-3wiwA:
undetectable		 2ya7A-3wiwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x05 PHOSPHATIDYLINOSITOL
5-PHOSPHATE 4-KINASE
TYPE-2 BETA

(Homo sapiens) 		PF01504
(PIP5K) 		4 ARG A 224
ILE A 414
LEU A 250
GLU A 246
 None
 1.02A 2ya7A-3x05A:
undetectable		 2ya7A-3x05A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aq1 SBSB PROTEIN

(Geobacillus
stearothermophilus) 		no annotation 4 ASP C 656
ILE C 642
LEU C 699
GLU C 706
 None
 1.01A 2ya7A-4aq1C:
undetectable		 2ya7A-4aq1C:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4atf BETA-AGARASE B

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		4 ASP A 103
ILE A 147
LEU A 129
TYR A  86
 None
 1.04A 2ya7A-4atfA:
1.8		 2ya7A-4atfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b92 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 ASP A  64
ILE A  63
LEU A 385
TYR A 244
 None
 1.08A 2ya7A-4b92A:
undetectable		 2ya7A-4b92A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 ARG A 115
ILE A 112
LEU A  48
GLU A  96
 None
 1.05A 2ya7A-4b9yA:
undetectable		 2ya7A-4b9yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bp8 OLIGOPEPTIDASE B

(Trypanosoma
brucei) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 ARG A 213
ILE A 255
LEU A 279
GLU A 264
 None
 1.08A 2ya7A-4bp8A:
9.3		 2ya7A-4bp8A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7w HEMAGGLUTININ-ESTERA
SE

(Murine
coronavirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 ARG A 265
ILE A 206
LEU A 292
GLU A 140
 None
 1.06A 2ya7A-4c7wA:
undetectable		 2ya7A-4c7wA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c9b PRE-MRNA-SPLICING
FACTOR CWC22 HOMOLOG

(Homo sapiens) 		PF02854
(MIF4G) 		4 ASP B 374
ILE B 238
LEU B 273
GLU B 231
 None
 1.07A 2ya7A-4c9bB:
undetectable		 2ya7A-4c9bB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ASP A 605
ILE A 487
LEU A 508
GLU A 594
 None
 1.05A 2ya7A-4cakA:
7.2		 2ya7A-4cakA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ASP A 605
ILE A 487
LEU A 508
TYR A 645
 None
 0.98A 2ya7A-4cakA:
7.2		 2ya7A-4cakA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cd8 ENDO-BETA-1,4-MANNAN
ASE

(Alicyclobacillus
acidocaldarius) 		no annotation 4 ARG A 237
ASP A 296
LEU A 287
GLU A 282
 None
None
None
BMA  A 401 (-2.7A)
 1.06A 2ya7A-4cd8A:
undetectable		 2ya7A-4cd8A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvu BETA-MANNOSIDASE

(Trichoderma
harzianum) 		PF00703
(Glyco_hydro_2) 		4 ARG A 161
ILE A  82
LEU A  61
TYR A  89
 None
 0.95A 2ya7A-4cvuA:
undetectable		 2ya7A-4cvuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy3 PHOSPHOGLYCERATE
OXIDOREDUCTASE

(Rhizobium etli) 		PF02826
(2-Hacid_dh_C) 		4 ARG A  27
ILE A  10
LEU A  47
GLU A  14
 None
 1.05A 2ya7A-4hy3A:
undetectable		 2ya7A-4hy3A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j6c CYTOCHROME P450
MONOOXYGENASE

(Nocardia
farcinica) 		PF00067
(p450) 		4 ASP A 302
ILE A 303
LEU A 305
GLU A 314
 None
 1.05A 2ya7A-4j6cA:
undetectable		 2ya7A-4j6cA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k49 ESTERASE YDII

(Escherichia
coli) 		no annotation 4 ASP C  25
ILE C  26
LEU C  61
GLU C  29
 None
 1.08A 2ya7A-4k49C:
undetectable		 2ya7A-4k49C:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ls9 DHH FAMILY PROTEIN

(Mycolicibacterium
smegmatis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 ARG A 190
ASP A 271
ILE A 272
LEU A 229
 None
 0.92A 2ya7A-4ls9A:
undetectable		 2ya7A-4ls9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mph D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF02557
(VanY) 		5 ARG A 127
ASP A 167
ILE A 220
LEU A 190
TYR A 215
 None
ZN  A 400 ( 1.8A)
None
None
None
 1.41A 2ya7A-4mphA:
undetectable		 2ya7A-4mphA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt6 RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 9

(Rattus
norvegicus) 		PF00018
(SH3_1)
PF00169
(PH)
PF00621
(RhoGEF) 		4 ASP A 374
ILE A 373
LEU A 401
GLU A 430
 None
 1.05A 2ya7A-4mt6A:
undetectable		 2ya7A-4mt6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oiv BILE ACID RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 ASP A 404
ILE A 402
LEU A 323
GLU A 409
 None
 1.06A 2ya7A-4oivA:
undetectable		 2ya7A-4oivA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7y MINICHROMOSOME
MAINTENANCE PROTEIN
MCM, CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus;
Sulfolobus
solfataricus) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ARG A1317
ASP A1321
ILE A1322
GLU A1933
 None
 1.00A 2ya7A-4r7yA:
undetectable		 2ya7A-4r7yA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoo LIPOTEICHOIC ACID
SYNTHASE

(Listeria
monocytogenes) 		PF00884
(Sulfatase) 		4 ILE A 341
LEU A 540
GLU A 315
TYR A 259
 None
 0.89A 2ya7A-4uooA:
undetectable		 2ya7A-4uooA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8l ENDO-1,4-BETA-XYLANA
SE C

(Paenibacillus
barcinonensis) 		PF00331
(Glyco_hydro_10) 		4 ARG A 445
ASP A 507
ILE A 509
LEU A 545
 None
CA  A1101 (-2.2A)
None
None
 0.89A 2ya7A-4w8lA:
undetectable		 2ya7A-4w8lA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 2
ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Drosophila
melanogaster) 		PF04084
(ORC2)
PF07034
(ORC3_N) 		4 ARG C 180
ASP B 416
ILE B 418
LEU B 454
 None
 1.00A 2ya7A-4xgcC:
undetectable		 2ya7A-4xgcC:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7l TYPE VI SECRETION
PROTEIN ICMF

(Escherichia
coli) 		PF06744
(IcmF_C) 		4 ARG A 938
ILE A 965
LEU A1096
GLU A1088
 None
 0.89A 2ya7A-4y7lA:
2.0		 2ya7A-4y7lA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8t AVRRXO1-ORF1
AVRRXO1-ORF2

(Xanthomonas
oryzae) 		no annotation 4 ASP B  68
ILE B  69
LEU B  60
GLU A 251
 None
 0.70A 2ya7A-4z8tB:
undetectable		 2ya7A-4z8tB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awn HEAVY CHAIN OF
3BC176 FAB

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ASP H  52
ILE H  51
LEU H  78
TYR H  27
 None
 1.07A 2ya7A-5awnH:
undetectable		 2ya7A-5awnH:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Bordetella
bronchiseptica) 		PF01522
(Polysacc_deac_1) 		4 ASP A  95
ILE A  93
LEU A 285
GLU A 180
 None
None
None
EDO  A 408 (-3.7A)
 0.96A 2ya7A-5bu6A:
undetectable		 2ya7A-5bu6A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5civ SIBLING BACTERIOCIN

(Paenibacillus
dendritiformis) 		PF08020
(DUF1706) 		4 ASP A 131
ILE A 130
LEU A  23
GLU A 123
 None
 1.07A 2ya7A-5civA:
undetectable		 2ya7A-5civA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 ASP A 684
ILE A 686
LEU A 675
GLU A 764
 None
 0.87A 2ya7A-5eawA:
undetectable		 2ya7A-5eawA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32

(Mycobacterium
marinum) 		PF00501
(AMP-binding) 		4 ASP A 568
ILE A 566
LEU A 587
GLU A 562
 None
 1.04A 2ya7A-5ey9A:
undetectable		 2ya7A-5ey9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h68 CHROMOSOME PARTITION
PROTEIN SMC

(Geobacillus
stearothermophilus) 		PF02463
(SMC_N) 		4 ASP A   7
ILE A  82
LEU A   3
GLU A  97
 None
 0.99A 2ya7A-5h68A:
undetectable		 2ya7A-5h68A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hif RECONSTRUCTED
LACTONASE ANCESTOR,
ANC1-MPH

(synthetic
construct) 		PF00753
(Lactamase_B) 		4 ASP A 221
ILE A 223
LEU A 269
TYR A  67
 ZN  A 401 ( 2.4A)
None
None
None
 1.06A 2ya7A-5hifA:
undetectable		 2ya7A-5hifA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8r PROTOCADHERIN
GAMMA-B3

(Homo sapiens) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 ASP A  58
ILE A  60
LEU A  74
GLU A  64
 None
 1.02A 2ya7A-5k8rA:
undetectable		 2ya7A-5k8rA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhi 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 6

(Homo sapiens) 		PF01399
(PCI)
PF10602
(RPN7) 		4 ARG Y 101
ASP Y 139
LEU Y 180
GLU Y 170
 None
 0.80A 2ya7A-5vhiY:
undetectable		 2ya7A-5vhiY:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 ASP A  66
ILE A  68
LEU A  50
GLU A  93
 None
 1.07A 2ya7A-5y7oA:
undetectable		 2ya7A-5y7oA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zdh TYPE II SECRETION
SYSTEM PROTEIN D

(Escherichia
coli) 		no annotation 4 ARG A 111
ILE A 143
LEU A 122
GLU A 117
 None
 1.04A 2ya7A-5zdhA:
undetectable		 2ya7A-5zdhA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bni LYSINE--TRNA LIGASE

(Cryptosporidium
parvum) 		no annotation 4 ARG A 107
ASP A 117
ILE A 118
LEU A  76
 None
 0.74A 2ya7A-6bniA:
undetectable		 2ya7A-6bniA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cdd NPL4 ZINC FINGER

(Chaetomium
thermophilum) 		no annotation 4 ARG A 276
ILE A 345
LEU A 286
GLU A 309
 None
 1.05A 2ya7A-6cddA:
undetectable		 2ya7A-6cddA:
11.30