SIMILAR PATTERNS OF AMINO ACIDS FOR 2Y7K_C_SALC1302_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1am5 | PEPSIN (Gadus morhua) |
PF00026(Asp) | 5 | GLY A 85GLY A 68HIS A 44PRO A 58ILE A 83 | None | 1.22A | 2y7kC-1am5A:undetectable | 2y7kC-1am5A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aor | ALDEHYDE FERREDOXINOXIDOREDUCTASE (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 5 | ILE A 389GLY A 396TYR A 385PHE A 395PHE A 374 | None | 1.25A | 2y7kC-1aorA:undetectable | 2y7kC-1aorA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ggm | GLYCINE--TRNA LIGASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | ILE A 240PHE A 243PHE A 194ARG A 311ILE A 193 | NoneNoneNoneGAP A1550 (-3.8A)None | 1.25A | 2y7kC-1ggmA:undetectable | 2y7kC-1ggmA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kpi | CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPIDSYNTHASE 2 (Mycobacteriumtuberculosis) |
PF02353(CMAS) | 5 | ILE A 243GLY A 244TYR A 247PHE A 288HIS A 182 | NoneNone10A A 901 ( 4.3A)10A A 901 ( 4.9A)CO3 A 902 (-3.8A) | 1.22A | 2y7kC-1kpiA:undetectable | 2y7kC-1kpiA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l2q | MONOMETHYLAMINEMETHYLTRANSFERASE (Methanosarcinabarkeri) |
PF05369(MtmB) | 5 | THR A 274GLY A 270GLY A 266HIS A 300ILE A 301 | None | 1.28A | 2y7kC-1l2qA:undetectable | 2y7kC-1l2qA:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m9u | EARTHWORMFIBRINOLYTIC ENZYME (Eisenia fetida) |
PF00089(Trypsin) | 5 | THR A 188ILE A 160GLY A 189GLY A 186PRO A 161 | None | 1.32A | 2y7kC-1m9uA:undetectable | 2y7kC-1m9uA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mg5 | ALCOHOLDEHYDROGENASE (Drosophilamelanogaster) |
PF00106(adh_short) | 5 | ILE A 18GLY A 19PHE A 11GLY A 92PRO A 182 | NAI A 850 (-3.9A)NoneNoneNAI A 850 (-4.6A)NAI A 850 (-3.8A) | 1.12A | 2y7kC-1mg5A:undetectable | 2y7kC-1mg5A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nnw | HYPOTHETICAL PROTEIN (Pyrococcusfuriosus) |
no annotation | 5 | PHE A 197GLY A 250HIS A 98PRO A 96ILE A 245 | None | 1.21A | 2y7kC-1nnwA:undetectable | 2y7kC-1nnwA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9i | MANGANESE CATALASE (Lactobacillusplantarum) |
PF05067(Mn_catalase) | 5 | GLY A 38GLY A 63PHE A 185HIS A 181HIS A 69 | NoneNoneNoneMN3 A 268 ( 3.2A)MN3 A 267 ( 3.3A) | 1.24A | 2y7kC-1o9iA:undetectable | 2y7kC-1o9iA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p0c | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Pelophylaxperezi) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | THR A1145GLY A1066GLY A1044PHE A1357ILE A1045 | None | 1.32A | 2y7kC-1p0cA:undetectable | 2y7kC-1p0cA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pss | PHOTOSYNTHETICREACTION CENTER (Rhodobactersphaeroides) |
PF00124(Photo_RC) | 5 | THR M 222ILE M 223GLY M 220HIS M 266ILE M 265 | U10 M 303 (-3.5A)NoneNone FE M 302 (-3.3A)U10 M 303 (-4.3A) | 1.21A | 2y7kC-1pssM:undetectable | 2y7kC-1pssM:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qnh | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Plasmodiumfalciparum) |
PF00160(Pro_isomerase) | 5 | ILE A 74GLY A 72PHE A 119PHE A 9ILE A 165 | None | 1.22A | 2y7kC-1qnhA:undetectable | 2y7kC-1qnhA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qox | BETA-GLUCOSIDASE (Bacilluscirculans) |
PF00232(Glyco_hydro_1) | 5 | ILE A 291GLY A 292TYR A 352GLY A 218PRO A 349 | None | 1.13A | 2y7kC-1qoxA:undetectable | 2y7kC-1qoxA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r9j | TRANSKETOLASE (Leishmaniamexicana) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ILE A 403GLY A 373PHE A 428PHE A 364ARG A 401 | None | 1.29A | 2y7kC-1r9jA:undetectable | 2y7kC-1r9jA:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v71 | HYPOTHETICAL PROTEINC320.14 INCHROMOSOME III (Schizosaccharomycespombe) |
PF00291(PALP) | 5 | THR A 239GLY A 183GLY A 236PHE A 56PRO A 151 | NonePLP A 350 (-3.3A)PLP A 350 (-4.7A)PLP A 350 (-4.7A)None | 1.10A | 2y7kC-1v71A:undetectable | 2y7kC-1v71A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve5 | THREONINE DEAMINASE (Thermusthermophilus) |
PF00291(PALP) | 5 | THR A 235GLY A 178GLY A 232PHE A 50PRO A 142 | NonePLP A 413 (-3.3A)PLP A 413 ( 4.7A)PLP A 413 (-4.6A)None | 1.00A | 2y7kC-1ve5A:undetectable | 2y7kC-1ve5A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wsv | AMINOMETHYLTRANSFERASE (Homo sapiens) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | THR A 92ILE A 98GLY A 97GLY A 276ILE A 280 | THR A 92 ( 0.8A)ILE A 98 ( 0.7A)GLY A 97 ( 0.0A)GLY A 276 ( 0.0A)ILE A 280 ( 0.7A) | 1.26A | 2y7kC-1wsvA:undetectable | 2y7kC-1wsvA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zy9 | ALPHA-GALACTOSIDASE (Thermotogamaritima) |
PF02065(Melibiase) | 5 | ILE A 326GLY A 367PHE A 348PRO A 260ILE A 352 | None | 1.24A | 2y7kC-1zy9A:undetectable | 2y7kC-1zy9A:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aeu | HYPOTHETICAL PROTEINMJ0158 (Methanocaldococcusjannaschii) |
PF03841(SelA) | 5 | THR A 52ILE A 54GLY A 55TYR A 58PHE A 59 | None | 1.06A | 2y7kC-2aeuA:undetectable | 2y7kC-2aeuA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3x | IRON-RESPONSIVEELEMENT BINDINGPROTEIN 1 (Homo sapiens) |
PF00330(Aconitase)PF00694(Aconitase_C) | 5 | ILE A 211GLY A 218GLY A 203ARG A 187ILE A 84 | None | 1.28A | 2y7kC-2b3xA:undetectable | 2y7kC-2b3xA:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gju | 252AA LONGHYPOTHETICAL PROTEIN (Pyrococcushorikoshii) |
no annotation | 5 | PHE A 197GLY A 250HIS A 98PRO A 96ILE A 245 | None | 1.18A | 2y7kC-2gjuA:undetectable | 2y7kC-2gjuA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2np5 | TRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF00440(TetR_N)PF13977(TetR_C_6) | 5 | THR A 143ILE A 141GLY A 142GLY A 190PRO A 81 | None | 1.10A | 2y7kC-2np5A:undetectable | 2y7kC-2np5A:25.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2psf | RENILLA-LUCIFERIN2-MONOOXYGENASE (Renillareniformis) |
PF00561(Abhydrolase_1) | 5 | GLY A 82GLY A 85HIS A 97PRO A 215ILE A 79 | None | 1.32A | 2y7kC-2psfA:undetectable | 2y7kC-2psfA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qk4 | TRIFUNCTIONAL PURINEBIOSYNTHETIC PROTEINADENOSINE-3 (Homo sapiens) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | THR A 316ILE A 313GLY A 271PHE A 293ILE A 272 | None | 1.27A | 2y7kC-2qk4A:undetectable | 2y7kC-2qk4A:20.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2uye | REGULATORY PROTEIN (Burkholderiacepacia) |
PF03466(LysR_substrate) | 5 | GLY A 152PHE A 167HIS A 169PRO A 246ILE A 273 | SCN A1307 (-3.6A)SCN A1303 (-4.7A)SCN A1303 (-4.4A)NoneSCN A1303 (-4.1A) | 1.22A | 2y7kC-2uyeA:32.6 | 2y7kC-2uyeA:70.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2uye | REGULATORY PROTEIN (Burkholderiacepacia) |
PF03466(LysR_substrate) | 8 | THR A 104ILE A 106GLY A 107GLY A 152PHE A 167HIS A 206PRO A 246ILE A 273 | SCN A1307 (-4.0A)SCN A1303 ( 4.9A)SCN A1303 (-3.5A)SCN A1307 (-3.6A)SCN A1303 (-4.7A)SCN A1307 (-3.6A)NoneSCN A1303 (-4.1A) | 0.77A | 2y7kC-2uyeA:32.6 | 2y7kC-2uyeA:70.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v84 | SPERMIDINE/PUTRESCINE ABC TRANSPORTER,PERIPLASMIC BINDINGPROTEIN (Treponemapallidum) |
PF13416(SBP_bac_8) | 5 | THR A 279ILE A 280PHE A 276GLY A 112PRO A 108 | None | 1.21A | 2y7kC-2v84A:3.3 | 2y7kC-2v84A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wtb | FATTY ACIDMULTIFUNCTIONALPROTEIN (ATMFP2) (Arabidopsisthaliana) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | ILE A 683GLY A 679TYR A 682GLY A 708ARG A 686 | None | 1.34A | 2y7kC-2wtbA:undetectable | 2y7kC-2wtbA:15.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2y7r | LYSR-TYPE REGULATORYPROTEIN (Burkholderiasp. DNT) |
PF03466(LysR_substrate) | 12 | THR A 104ILE A 106GLY A 107TYR A 110PHE A 111GLY A 152PHE A 167HIS A 169HIS A 206PRO A 246ARG A 248ILE A 273 | None | 0.61A | 2y7kC-2y7rA:32.5 | 2y7kC-2y7rA:99.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z22 | PERIPLASMICPHOSPHATE-BINDINGPROTEIN (Yersinia pestis) |
no annotation | 5 | GLY X 6GLY X 53PHE X 277PRO X 12ILE X 258 | None | 1.13A | 2y7kC-2z22X:10.2 | 2y7kC-2z22X:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a24 | ALPHA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 5 | ILE A 123GLY A 122TYR A 119ARG A 117ILE A 272 | None | 1.23A | 2y7kC-3a24A:undetectable | 2y7kC-3a24A:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aoe | GLUTAMATEDEHYDROGENASE (Thermusthermophilus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ILE A 140GLY A 141GLY A 145HIS A 69ARG A 45 | None | 0.71A | 2y7kC-3aoeA:undetectable | 2y7kC-3aoeA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqc | COMPONENT B OFHEXAPRENYLDIPHOSPHATE SYNTHASE (Micrococcusluteus) |
PF00348(polyprenyl_synt) | 5 | PHE B 51GLY B 204PHE B 199HIS B 317ILE B 203 | None | 1.34A | 2y7kC-3aqcB:undetectable | 2y7kC-3aqcB:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | THR A 391ILE A 370GLY A 386TYR A 385GLY A 365 | None | 0.95A | 2y7kC-3d1jA:undetectable | 2y7kC-3d1jA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0g | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB4DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB7 (Schizosaccharomycespombe) |
PF00575(S1)PF03874(RNA_pol_Rpb4)PF03876(SHS2_Rpb7-N) | 5 | THR G 153ILE G 158GLY G 41PHE D 19PRO G 82 | None | 1.34A | 2y7kC-3h0gG:undetectable | 2y7kC-3h0gG:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if9 | GLYCINE OXIDASE (Bacillussubtilis) |
PF01266(DAO) | 5 | ILE A 312GLY A 313PHE A 210HIS A 327PRO A 310 | None | 1.34A | 2y7kC-3if9A:undetectable | 2y7kC-3if9A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nrn | UNCHARACTERIZEDPROTEIN PF1083 (Pyrococcusfuriosus) |
PF01593(Amino_oxidase) | 5 | ILE A 294GLY A 296PHE A 297PHE A 341ILE A 340 | None | 1.31A | 2y7kC-3nrnA:undetectable | 2y7kC-3nrnA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8q | SHIKIMATE5-DEHYDROGENASE IALPHA (Vibrio cholerae) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 5 | THR B 153ILE B 129PHE B 208PRO B 201ILE B 207 | None | 1.25A | 2y7kC-3o8qB:3.5 | 2y7kC-3o8qB:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pvd | CAPSID (Norwalk virus) |
PF08435(Calici_coat_C) | 5 | THR A 275GLY A 321GLY A 324PHE A 286PRO A 403 | None | 1.32A | 2y7kC-3pvdA:undetectable | 2y7kC-3pvdA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pvd | CAPSID (Norwalk virus) |
PF08435(Calici_coat_C) | 5 | THR A 442ILE A 388GLY A 437GLY A 440ARG A 351 | None | 1.18A | 2y7kC-3pvdA:undetectable | 2y7kC-3pvdA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q60 | ROP5B (Toxoplasmagondii) |
PF14531(Kinase-like) | 5 | ILE A 453GLY A 450TYR A 454GLY A 504PHE A 489 | None | 1.12A | 2y7kC-3q60A:undetectable | 2y7kC-3q60A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3s | OXIDOREDUCTASE (Salmonellaenterica) |
PF13561(adh_short_C2) | 5 | THR A 254GLY A 251PHE A 250GLY A 230ILE A 232 | NoneNoneNoneNAD A 300 (-4.7A)NAD A 300 (-4.3A) | 0.97A | 2y7kC-3r3sA:undetectable | 2y7kC-3r3sA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rj9 | ALCOHOLDEHYDROGENASE (Scaptodrosophilalebanonensis) |
PF00106(adh_short) | 5 | ILE A 17GLY A 18PHE A 10GLY A 91PRO A 181 | NAD A 850 (-4.0A)NoneNoneNAD A 850 (-4.7A)NAD A 850 (-3.9A) | 1.11A | 2y7kC-3rj9A:undetectable | 2y7kC-3rj9A:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3top | MALTASE-GLUCOAMYLASE, INTESTINAL (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 5 | THR A1490GLY A1517PHE A1544HIS A1170ILE A1549 | None | 1.28A | 2y7kC-3topA:undetectable | 2y7kC-3topA:13.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttg | PUTATIVEAMINOMETHYLTRANSFERASE (Leptospirillumrubarum) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | THR A 292GLY A 303GLY A 301PHE A -2ARG A 327 | None | 1.32A | 2y7kC-3ttgA:undetectable | 2y7kC-3ttgA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0k | RCAMP (Entacmaeaquadricolor) |
PF01353(GFP)PF13499(EF-hand_7) | 5 | GLY A 251TYR A 247PHE A 277GLY A 274ILE A 253 | None | 1.16A | 2y7kC-3u0kA:undetectable | 2y7kC-3u0kA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3va7 | KLLA0E08119P (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | THR A1643ILE A1627GLY A1616TYR A1628GLY A1641 | NoneNoneNoneURE A1902 (-4.3A)None | 1.02A | 2y7kC-3va7A:undetectable | 2y7kC-3va7A:10.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3va7 | KLLA0E08119P (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | THR A1643ILE A1627GLY A1616TYR A1628PRO A1590 | NoneNoneNoneURE A1902 (-4.3A)None | 1.26A | 2y7kC-3va7A:undetectable | 2y7kC-3va7A:10.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w04 | DWARF 88 ESTERASE (Oryza sativa) |
PF12697(Abhydrolase_6) | 5 | ILE A 170GLY A 145GLY A 77HIS A 300PRO A 299 | None | 1.35A | 2y7kC-3w04A:undetectable | 2y7kC-3w04A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | THR A1011ILE A 909GLY A 907GLY A1007PHE A 926 | None | 0.98A | 2y7kC-3w9iA:undetectable | 2y7kC-3w9iA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wy2 | ALPHA-GLUCOSIDASE (Halomonas sp.H11) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 5 | THR A 226GLY A 228PHE A 166HIS A 240ILE A 146 | NoneNoneBGC A 605 ( 3.8A)NoneNone | 1.22A | 2y7kC-3wy2A:undetectable | 2y7kC-3wy2A:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axn | CHITINASE C1 (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 5 | TYR A 207PHE A 180GLY A 211PHE A 235PRO A 263 | None | 1.31A | 2y7kC-4axnA:undetectable | 2y7kC-4axnA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4be3 | ALGINATE LYASE,FAMILY PL7 (Zobelliagalactanivorans) |
PF08787(Alginate_lyase2) | 5 | THR A 102ILE A 94GLY A 57PHE A 73ILE A 324 | None | 1.00A | 2y7kC-4be3A:undetectable | 2y7kC-4be3A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dmm | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Synechococcuselongatus) |
PF13561(adh_short_C2) | 5 | ILE A 191GLY A 214TYR A 213GLY A 244ILE A 208 | None | 1.26A | 2y7kC-4dmmA:undetectable | 2y7kC-4dmmA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dok | SIMILARITY TOCHALCONE-FLAVONONEISOMERASE (Arabidopsisthaliana) |
PF02431(Chalcone) | 5 | THR A 196ILE A 45GLY A 29GLY A 27ARG A 89 | None | 1.30A | 2y7kC-4dokA:undetectable | 2y7kC-4dokA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fc7 | PEROXISOMAL2,4-DIENOYL-COAREDUCTASE (Homo sapiens) |
PF13561(adh_short_C2) | 5 | THR A 214ILE A 40GLY A 39GLY A 216PRO A 208 | NAP A 401 (-3.0A)NAP A 401 (-4.0A)NAP A 401 (-3.2A)NAP A 401 (-3.2A)NAP A 401 (-4.0A) | 1.34A | 2y7kC-4fc7A:undetectable | 2y7kC-4fc7A:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i9y | E3 SUMO-PROTEINLIGASE RANBP2 (Homo sapiens) |
PF00160(Pro_isomerase) | 5 | ILE A 67GLY A 65PHE A 112PHE A 8ILE A 158 | None | 1.26A | 2y7kC-4i9yA:undetectable | 2y7kC-4i9yA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imi | SYMPLEKIN (Drosophilamelanogaster) |
PF11935(DUF3453) | 5 | ILE A 130GLY A 128TYR A 131PHE A 180ILE A 158 | None | 1.27A | 2y7kC-4imiA:undetectable | 2y7kC-4imiA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irn | PROLYL-ACPDEHYDROGENASE ([Oscillatoria]sp. PCC 6506) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | ILE A 370GLY A 366GLY A 133PHE A 237ILE A 136 | NoneFAD A 400 ( 4.8A)FAD A 400 (-3.5A)NoneNone | 1.18A | 2y7kC-4irnA:undetectable | 2y7kC-4irnA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhz | BETA-GLUCURONIDASE (Escherichiacoli) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 5 | THR A 291GLY A 292PHE A 293GLY A 322ILE A 321 | None | 1.26A | 2y7kC-4jhzA:undetectable | 2y7kC-4jhzA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jro | FABG PROTEIN (Listeriamonocytogenes) |
PF13561(adh_short_C2) | 5 | ILE A 188GLY A 214TYR A 213GLY A 243ILE A 208 | None | 1.23A | 2y7kC-4jroA:undetectable | 2y7kC-4jroA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwy | GLUTAMATE RECEPTORIONOTROPIC, NMDA 2D (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 5 | THR A 168GLY A 167TYR A 192PHE A 166ARG A 191 | None | 1.25A | 2y7kC-4jwyA:8.2 | 2y7kC-4jwyA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4muz | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Archaeoglobusfulgidus) |
PF00215(OMPdecase) | 5 | THR A 131ILE A 162TYR A 128PRO A 186ILE A 183 | NoneBMP A 301 ( 4.9A)NoneBMP A 301 (-4.3A)None | 1.18A | 2y7kC-4muzA:undetectable | 2y7kC-4muzA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzr | PGT135 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | GLY H 31TYR H 32GLY H 31PRO H 100ARG H 96 | None | 1.34A | 2y7kC-4nzrH:undetectable | 2y7kC-4nzrH:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pde | PROTEIN FDHD (Escherichiacoli) |
PF02634(FdhD-NarQ) | 5 | GLY A 133GLY A 74HIS A 52ARG A 112ILE A 75 | None | 1.34A | 2y7kC-4pdeA:undetectable | 2y7kC-4pdeA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pzc | 3-HYDROXYACYL-COADEHYDROGENASE (Cupriavidusnecator) |
PF00725(3HCDH)PF02737(3HCDH_N) | 5 | THR A 159GLY A 156GLY A 138PHE A 187ILE A 154 | None | 1.34A | 2y7kC-4pzcA:undetectable | 2y7kC-4pzcA:21.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rns | PCP DEGRADATIONTRANSCRIPTIONALACTIVATION PROTEIN (Sphingobiumchlorophenolicum) |
PF03466(LysR_substrate) | 5 | GLY A 107GLY A 152PHE A 167PRO A 248ARG A 250 | None | 0.73A | 2y7kC-4rnsA:24.6 | 2y7kC-4rnsA:32.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rns | PCP DEGRADATIONTRANSCRIPTIONALACTIVATION PROTEIN (Sphingobiumchlorophenolicum) |
PF03466(LysR_substrate) | 5 | GLY A 107PHE A 151PHE A 167PRO A 248ARG A 250 | None | 1.20A | 2y7kC-4rnsA:24.6 | 2y7kC-4rnsA:32.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rvs | PROBABLE QUINONEREDUCTASE QOR(NADPH:QUINONEREDUCTASE)(ZETA-CRYSTALLINHOMOLOG PROTEIN) (Mycobacteriumtuberculosis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 5PHE A 58GLY A 61HIS A 313ARG A 48 | None | 1.17A | 2y7kC-4rvsA:undetectable | 2y7kC-4rvsA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxu | PERIPLASMICSUGAR-BINDINGPROTEIN (Chloroflexusaurantiacus) |
PF13407(Peripla_BP_4) | 5 | ILE A 135TYR A 137GLY A 54PHE A 72ILE A 55 | None | 1.21A | 2y7kC-4rxuA:2.8 | 2y7kC-4rxuA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rzh | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Synechocystissp. PCC 6803) |
PF13561(adh_short_C2) | 5 | ILE A 189GLY A 212TYR A 211GLY A 242ILE A 206 | None | 1.17A | 2y7kC-4rzhA:undetectable | 2y7kC-4rzhA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uad | IMPORTIN SUBUNITALPHA-7 (Homo sapiens) |
PF00514(Arm)PF16186(Arm_3) | 5 | THR A 410ILE A 414GLY A 409PHE A 380ILE A 375 | None | 1.29A | 2y7kC-4uadA:undetectable | 2y7kC-4uadA:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v08 | UL26 (Suidalphaherpesvirus1) |
PF00716(Peptidase_S21) | 5 | THR A 140ILE A 141GLY A 139GLY A 135ILE A 134 | NoneNoneNoneDFP A 300 (-3.6A)None | 1.34A | 2y7kC-4v08A:undetectable | 2y7kC-4v08A:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wky | BETA-KETOACYLSYNTHASE (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | THR A 50ILE A 78GLY A 77GLY A 48PRO A 80 | None | 1.32A | 2y7kC-4wkyA:undetectable | 2y7kC-4wkyA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z64 | PHYTOSULFOKINERECEPTOR 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | GLY A 161PHE A 184GLY A 139HIS A 166ILE A 140 | NoneNoneNoneNAG A 702 (-4.8A)None | 1.06A | 2y7kC-4z64A:undetectable | 2y7kC-4z64A:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bn4 | NEQ263 (Nanoarchaeumequitans) |
PF00006(ATP-synt_ab) | 5 | THR B 113ILE B 115GLY B 114PHE B 383PRO B 316 | None | 1.25A | 2y7kC-5bn4B:1.3 | 2y7kC-5bn4B:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cg0 | BETA-GLUCOSIDASE (Spodopterafrugiperda) |
PF00232(Glyco_hydro_1) | 5 | THR A 184GLY A 243PHE A 280PRO A 188ILE A 279 | None | 1.33A | 2y7kC-5cg0A:undetectable | 2y7kC-5cg0A:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4v | NUCLEOPROTEIN,PHOSPHOPROTEIN (Measlesmorbillivirus) |
PF00973(Paramyxo_ncap)PF13825(Paramyxo_PNT) | 5 | THR A 51ILE A 16GLY A 52GLY A 47HIS A 14 | None | 1.32A | 2y7kC-5e4vA:undetectable | 2y7kC-5e4vA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb5 | HNL ISOENZYME 5 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | THR A 181ILE A 167GLY A 321GLY A 159ILE A 158 | None | 1.32A | 2y7kC-5eb5A:undetectable | 2y7kC-5eb5A:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epo | 7-ALPHA-HYDROXYSTEROID DEYDROGENASE (Clostridiumsardiniense) |
PF13561(adh_short_C2) | 5 | THR A 193ILE A 191GLY A 192GLY A 17PRO A 188 | NAP A 301 (-2.9A)NAP A 301 (-3.9A)NoneNAP A 301 (-3.3A)NAP A 301 (-3.7A) | 1.32A | 2y7kC-5epoA:undetectable | 2y7kC-5epoA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEASOME SUBUNITALPHA, PUTATIVE (Plasmodiumfalciparum) |
PF00227(Proteasome)PF10584(Proteasome_A_N) | 5 | THR A 35GLY A 88GLY A 175PRO A 162ILE A 174 | None | 1.32A | 2y7kC-5fmgA:undetectable | 2y7kC-5fmgA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fnu | KELCH-LIKEECH-ASSOCIATEDPROTEIN 1 (Mus musculus) |
PF01344(Kelch_1) | 5 | THR A 560ILE A 328TYR A 329HIS A 562PRO A 347 | None | 1.26A | 2y7kC-5fnuA:undetectable | 2y7kC-5fnuA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hct | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | THR A 212ILE A 214GLY A 201PHE A 262PRO A 228 | NoneNoneNoneNoneGOL A 403 ( 4.0A) | 1.13A | 2y7kC-5hctA:undetectable | 2y7kC-5hctA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | THR A1643ILE A1627GLY A1616TYR A1628GLY A1641 | None | 1.02A | 2y7kC-5i8iA:2.3 | 2y7kC-5i8iA:7.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | THR A1643ILE A1627GLY A1616TYR A1628PRO A1590 | None | 1.25A | 2y7kC-5i8iA:2.3 | 2y7kC-5i8iA:7.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldx | NADH DEHYDROGENASE[UBIQUINONE] 1 ALPHASUBCOMPLEX SUBUNIT11 (Bos taurus) |
PF02466(Tim17) | 5 | ILE Y 91GLY Y 92TYR Y 89PHE Y 69GLY Y 118 | None | 1.27A | 2y7kC-5ldxY:undetectable | 2y7kC-5ldxY:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5npa | LOQUACIOUS (Drosophilamelanogaster) |
PF00035(dsrm) | 5 | THR A 40ILE A 41GLY A 52GLY A 54ARG A 62 | None | 1.28A | 2y7kC-5npaA:undetectable | 2y7kC-5npaA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5okz | EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae) |
PF14382(ECR1_N)PF15985(KH_6) | 5 | ILE H 128GLY H 129GLY H 229PHE H 199ARG H 115 | NoneNoneNoneNone CL H 401 (-3.9A) | 1.01A | 2y7kC-5okzH:undetectable | 2y7kC-5okzH:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy0 | PHOTOSYSTEM IREACTION CENTERSUBUNIT II (Synechocystissp. PCC 6803) |
no annotation | 5 | THR 4 33ILE 4 80TYR 4 83PHE 4 104ARG 4 73 | None | 1.31A | 2y7kC-5oy04:undetectable | 2y7kC-5oy04:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5p60 | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | THR A 212ILE A 214GLY A 201PHE A 262PRO A 228 | None | 1.09A | 2y7kC-5p60A:undetectable | 2y7kC-5p60A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swj | PROBABLE ATPSYNTHASE SPAL/MXIB (Shigellaflexneri) |
PF00006(ATP-synt_ab) | 5 | THR A 138ILE A 140GLY A 139PHE A 407PRO A 340 | None | 1.31A | 2y7kC-5swjA:1.4 | 2y7kC-5swjA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ul4 | OXSB PROTEIN (Bacillusmegaterium) |
PF02310(B12-binding) | 5 | ILE A 298GLY A 296GLY A 349ARG A 302ILE A 354 | None | 1.24A | 2y7kC-5ul4A:undetectable | 2y7kC-5ul4A:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8x | LIPID-A-DISACCHARIDESYNTHASE (Escherichiacoli) |
no annotation | 6 | THR A 140ILE A 136GLY A 137HIS A 119PRO A 123ARG A 132 | None | 1.39A | 2y7kC-5w8xA:undetectable | 2y7kC-5w8xA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wl7 | ENGINEERED CHALCONEISOMERASE ANCCHI* (unidentified) |
no annotation | 5 | THR A 199ILE A 48GLY A 32GLY A 30ARG A 92 | None | 1.25A | 2y7kC-5wl7A:undetectable | 2y7kC-5wl7A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq7 | PRECURSOR FOR MSUBUNITS OFPHOTOSYNTHETICREACTION CENTER (Roseiflexuscastenholzii) |
no annotation | 5 | THR M 545ILE M 546GLY M 543HIS M 589ILE M 588 | MQE M 701 (-4.0A)NoneNone FE L1005 (-3.2A)MQE M 701 (-4.4A) | 1.20A | 2y7kC-5yq7M:undetectable | 2y7kC-5yq7M:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bka | NITRONATEMONOOXYGENASE (Cyberlindneramrakii) |
no annotation | 5 | GLY A 47PHE A 148HIS A 81PRO A 322ARG A 296 | None | 1.26A | 2y7kC-6bkaA:undetectable | 2y7kC-6bkaA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bqc | CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPIDSYNTHASE (Escherichiacoli) |
no annotation | 5 | GLY A 314TYR A 317PHE A 358GLY A 269HIS A 266 | NoneLOP A 402 ( 3.7A)LOP A 402 ( 4.6A)NoneCO3 A 401 (-4.0A) | 1.25A | 2y7kC-6bqcA:undetectable | 2y7kC-6bqcA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cf8 | LYTICTRANSGLYCOSYLASE (Campylobacterjejuni) |
no annotation | 5 | THR A 470ILE A 467GLY A 468GLY A 465HIS A 445 | None | 1.07A | 2y7kC-6cf8A:undetectable | 2y7kC-6cf8A:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fmq | - (-) |
no annotation | 5 | THR A 560ILE A 328TYR A 329HIS A 562PRO A 347 | None | 1.18A | 2y7kC-6fmqA:undetectable | 2y7kC-6fmqA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g72 | NADH DEHYDROGENASE[UBIQUINONE] 1 ALPHASUBCOMPLEX SUBUNIT11 (Mus musculus) |
no annotation | 5 | ILE Y 91GLY Y 92TYR Y 89PHE Y 69GLY Y 118 | None | 1.32A | 2y7kC-6g72Y:undetectable | 2y7kC-6g72Y:17.92 |