SIMILAR PATTERNS OF AMINO ACIDS FOR 2Y7K_A_SALA1303

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)

(Enterobacter
cloacae) 		PF13354
(Beta-lactamase2) 		4 PRO A 226
SER A 224
ILE A 287
TRP A 229
 None
 0.92A 2y7kA-1bueA:
undetectable		 2y7kA-1bueA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dy6 CARBAPENEM-HYDROLYSI
NG BETA-LACTAMASE
SME-1

(Serratia
marcescens) 		PF13354
(Beta-lactamase2) 		4 PRO A 226
SER A 224
ILE A 287
TRP A 229
 None
 0.90A 2y7kA-1dy6A:
undetectable		 2y7kA-1dy6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 PRO A 774
ILE A 789
PRO A 777
TRP A 775
 None
 1.00A 2y7kA-1h0hA:
undetectable		 2y7kA-1h0hA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfu LACCASE 1

(Coprinopsis
cinerea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 PRO A  86
SER A  62
PRO A 353
GLY A  81
 None
 0.96A 2y7kA-1hfuA:
undetectable		 2y7kA-1hfuA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hym HYDROLYZED CUCURBITA
MAXIMA TRYPSIN
INHIBITOR V

(Cucurbita
maxima) 		PF00280
(potato_inhibit) 		4 PRO A  29
ILE A  24
PRO A   4
GLY A   5
 None
 0.97A 2y7kA-1hymA:
undetectable		 2y7kA-1hymA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1inl SPERMIDINE SYNTHASE

(Thermotoga
maritima) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 SER A 171
PHE A 187
ILE A 169
GLY A 153
 None
 0.93A 2y7kA-1inlA:
undetectable		 2y7kA-1inlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kae HISTIDINOL
DEHYDROGENASE

(Escherichia
coli) 		PF00815
(Histidinol_dh) 		4 PRO A 132
SER A 161
ILE A 169
GLY A 134
 NAD  A1201 (-3.6A)
None
None
None
 0.90A 2y7kA-1kaeA:
undetectable		 2y7kA-1kaeA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqf FORMATE
DEHYDROGENASE,
NITRATE-INDUCIBLE,
CYTOCHROME B556(FDN)
SUBUNIT

(Escherichia
coli) 		PF01292
(Ni_hydr_CYTB) 		4 PRO C  58
ILE C  62
GLY C 131
TRP C 135
 HEM  C 809 (-4.2A)
None
HEM  C 809 (-3.7A)
None
 0.68A 2y7kA-1kqfC:
undetectable		 2y7kA-1kqfC:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kve SMK TOXIN

(Millerozyma
farinosa) 		no annotation 4 PRO B 218
PHE A  65
ILE B 203
GLY A  75
 None
 0.88A 2y7kA-1kveB:
undetectable		 2y7kA-1kveB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1on9 METHYLMALONYL-COA
CARBOXYLTRANSFERASE
12S SUBUNIT

(Propionibacterium
freudenreichii) 		PF01039
(Carboxyl_trans) 		4 PRO A 376
ILE A 385
PRO A 372
GLY A 373
 None
 0.92A 2y7kA-1on9A:
0.0		 2y7kA-1on9A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pc3 PHOSPHATE-BINDING
PROTEIN 1

(Mycobacterium
tuberculosis) 		PF12849
(PBP_like_2) 		4 PHE A 312
PRO A  47
GLY A  46
TRP A  45
 None
 0.96A 2y7kA-1pc3A:
11.8		 2y7kA-1pc3A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pci PROCARICAIN

(Carica papaya) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 SER A  62
ILE A 148
PRO A 152
GLY A 151
 None
 0.93A 2y7kA-1pciA:
undetectable		 2y7kA-1pciA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6c ALKALINE SERINE
PROTEASE

(Pseudoalteromonas
sp. AS-11) 		PF00082
(Peptidase_S8)
PF02225
(PA) 		4 PRO A 373
ILE A 154
PRO A 201
GLY A 200
 None
 0.99A 2y7kA-1v6cA:
undetectable		 2y7kA-1v6cA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1va9 DOWN SYNDROME CELL
ADHESION MOLECULE
LIKE-PROTEIN 1B

(Homo sapiens) 		PF00041
(fn3) 		4 PRO A  19
ILE A  48
PRO A 105
GLY A 104
 None
 0.98A 2y7kA-1va9A:
undetectable		 2y7kA-1va9A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vm6 DIHYDRODIPICOLINATE
REDUCTASE

(Thermotoga
maritima) 		PF01113
(DapB_N)
PF05173
(DapB_C) 		4 SER A  99
ILE A 102
PRO A 161
GLY A 162
 None
 0.94A 2y7kA-1vm6A:
undetectable		 2y7kA-1vm6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpb PUTATIVE MODULATOR
OF DNA GYRASE

(Bacteroides
thetaiotaomicron) 		PF01523
(PmbA_TldD) 		4 PRO A 241
SER A 244
ILE A 426
GLY A 415
 None
 0.91A 2y7kA-1vpbA:
undetectable		 2y7kA-1vpbA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE

(Bacillus
subtilis) 		PF08007
(Cupin_4) 		4 PRO A 108
ILE A  58
PRO A  44
GLY A  45
 None
 0.97A 2y7kA-1vrbA:
undetectable		 2y7kA-1vrbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrg PROPIONYL-COA
CARBOXYLASE, BETA
SUBUNIT

(Thermotoga
maritima) 		PF01039
(Carboxyl_trans) 		4 PRO A 367
ILE A 376
PRO A 363
GLY A 364
 None
 0.91A 2y7kA-1vrgA:
undetectable		 2y7kA-1vrgA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0u HYPOTHETICAL
METHYLMALONYL-COA
DECARBOXYLASE ALPHA
SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01039
(Carboxyl_trans) 		4 PRO A 375
ILE A 384
PRO A 371
GLY A 372
 None
 0.91A 2y7kA-1x0uA:
undetectable		 2y7kA-1x0uA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zoq INTERFERON
REGULATORY FACTOR 3

(Homo sapiens) 		PF10401
(IRF-3) 		4 PRO A 223
ILE A 220
PRO A 239
GLY A 240
 None
 1.00A 2y7kA-1zoqA:
undetectable		 2y7kA-1zoqA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1g ACID PHOSPHATASE

(Francisella
tularensis) 		PF04185
(Phosphoesterase) 		4 PHE A  41
ILE A 384
PRO A 177
GLY A 178
 None
 0.78A 2y7kA-2d1gA:
undetectable		 2y7kA-2d1gA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkn 3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Pseudomonas sp.
B-0831) 		PF13561
(adh_short_C2) 		4 SER A   2
ILE A   4
PRO A 230
GLY A 229
 None
 0.93A 2y7kA-2dknA:
undetectable		 2y7kA-2dknA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drq XYLANASE Y

(Bacillus
halodurans) 		PF01270
(Glyco_hydro_8) 		4 PRO A 381
PHE A   9
ILE A 378
TRP A 210
 None
 0.97A 2y7kA-2drqA:
undetectable		 2y7kA-2drqA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2esn PROBABLE
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 PRO A  94
SER A  97
PHE A 101
TRP A 294
 None
 0.31A 2y7kA-2esnA:
16.0		 2y7kA-2esnA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqz R.ECL18KI

(Enterobacter
cloacae) 		PF09019
(EcoRII-C) 		4 SER A 278
ILE A 145
PRO A 164
GLY A 165
 None
 0.91A 2y7kA-2fqzA:
undetectable		 2y7kA-2fqzA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT

(Acinetobacter
baumannii) 		PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 PRO A 231
PHE A 183
ILE A 161
GLY A 197
 None
 0.75A 2y7kA-2jbrA:
undetectable		 2y7kA-2jbrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pzk PUTATIVE NUCLEOTIDE
SUGAR EPIMERASE/
DEHYDRATASE

(Bordetella
bronchiseptica) 		PF01370
(Epimerase) 		4 PRO A 133
ILE A 128
PRO A 136
GLY A 121
 None
 0.98A 2y7kA-2pzkA:
undetectable		 2y7kA-2pzkA:
21.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2uye REGULATORY PROTEIN

(Burkholderia
cepacia) 		PF03466
(LysR_substrate) 		7 PRO A  92
SER A  95
PHE A  99
ILE A 126
PRO A 285
GLY A 286
TRP A 289
 None
 0.42A 2y7kA-2uyeA:
30.2		 2y7kA-2uyeA:
70.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vak SIGMA A

(Avian
orthoreovirus) 		PF03084
(Sigma_1_2) 		4 PRO A 285
ILE A 376
GLY A 381
TRP A 409
 None
 0.99A 2y7kA-2vakA:
undetectable		 2y7kA-2vakA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2veo LIPASE A

(Moesziomyces
antarcticus) 		PF03583
(LIP) 		4 SER A 377
PHE A  88
ILE A 381
TRP A 129
 None
 0.76A 2y7kA-2veoA:
undetectable		 2y7kA-2veoA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xxz LYSINE-SPECIFIC
DEMETHYLASE 6B

(Homo sapiens) 		PF02373
(JmjC) 		4 ILE A1418
PRO A1385
GLY A1386
TRP A1468
 None
 0.97A 2y7kA-2xxzA:
undetectable		 2y7kA-2xxzA:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2y7r LYSR-TYPE REGULATORY
PROTEIN

(Burkholderia
sp. DNT) 		PF03466
(LysR_substrate) 		7 PRO A  92
SER A  95
PHE A  99
ILE A 126
PRO A 285
GLY A 286
TRP A 289
 None
 0.55A 2y7kA-2y7rA:
30.6		 2y7kA-2y7rA:
99.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus) 		PF00142
(Fer4_NifH) 		4 PRO A  67
SER A 115
ILE A  84
GLY A 126
 None
None
EPE  A1298 (-4.9A)
SF4  A1302 (-3.9A)
 0.97A 2y7kA-2ynmA:
undetectable		 2y7kA-2ynmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3azq AMINOPEPTIDASE

(Streptomyces
morookaense) 		PF00326
(Peptidase_S9) 		4 PRO A 251
SER A 254
ILE A 256
GLY A 305
 None
 0.95A 2y7kA-3azqA:
undetectable		 2y7kA-3azqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b40 PROBABLE DIPEPTIDASE

(Pseudomonas
aeruginosa) 		PF01244
(Peptidase_M19) 		4 PRO A  63
ILE A  60
PRO A  78
GLY A  79
 None
 1.00A 2y7kA-3b40A:
undetectable		 2y7kA-3b40A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE

(Conticribra
weissflogii) 		no annotation 4 PRO A 277
ILE A 260
PRO A 280
GLY A 282
 None
 0.99A 2y7kA-3boeA:
undetectable		 2y7kA-3boeA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE

(Vibrio cholerae) 		PF00793
(DAHP_synth_1) 		4 PRO A 195
PHE A  22
ILE A 197
PRO A  12
 None
 0.99A 2y7kA-3e9aA:
undetectable		 2y7kA-3e9aA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3feo MBT
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF02820
(MBT) 		4 PRO A 116
PHE A 129
GLY A  82
TRP A  64
 None
 0.92A 2y7kA-3feoA:
undetectable		 2y7kA-3feoA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhh OUTER MEMBRANE HEME
RECEPTOR SHUA

(Shigella
dysenteriae) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 PRO A 546
ILE A 544
PRO A  46
GLY A  47
 None
 0.96A 2y7kA-3fhhA:
undetectable		 2y7kA-3fhhA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fo8 TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF17481
(Phage_sheath_1N) 		5 SER D  93
PHE D 210
ILE D 193
PRO D 220
GLY D 221
 None
 1.14A 2y7kA-3fo8D:
undetectable		 2y7kA-3fo8D:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3foa TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N) 		5 SER A  93
PHE A 210
ILE A 193
PRO A 220
GLY A 221
 None
 1.16A 2y7kA-3foaA:
undetectable		 2y7kA-3foaA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gms PUTATIVE
NADPH:QUINONE
REDUCTASE

(Bacillus
thuringiensis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 SER A  45
ILE A 125
PRO A  64
GLY A  65
 None
 0.99A 2y7kA-3gmsA:
undetectable		 2y7kA-3gmsA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2n TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		5 SER U  93
PHE U 210
ILE U 193
PRO U 220
GLY U 221
 None
 1.16A 2y7kA-3j2nU:
undetectable		 2y7kA-3j2nU:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyh MRNA-CAPPING ENZYME
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C) 		4 SER C 291
PHE C 317
ILE C 261
PRO C 265
 None
 0.96A 2y7kA-3kyhC:
undetectable		 2y7kA-3kyhC:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5k HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 1A

(Homo sapiens) 		PF13419
(HAD_2) 		4 SER A 114
PHE A 155
ILE A 154
GLY A 180
 None
 0.97A 2y7kA-3l5kA:
undetectable		 2y7kA-3l5kA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE

(Methanosarcina
mazei) 		PF02743
(dCache_1) 		4 PRO A 284
SER A 291
ILE A 259
GLY A 265
 None
 0.91A 2y7kA-3li9A:
undetectable		 2y7kA-3li9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nom GLUTAMINE
CYCLOTRANSFERASE

(Zymomonas
mobilis) 		PF05096
(Glu_cyclase_2) 		4 SER A  36
ILE A  33
PRO A 219
GLY A 218
 None
 0.94A 2y7kA-3nomA:
undetectable		 2y7kA-3nomA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN

(Chlorobaculum
tepidum) 		PF08534
(Redoxin) 		4 PRO A 139
SER A 141
PHE A 163
ILE A 154
 None
 0.93A 2y7kA-3or5A:
undetectable		 2y7kA-3or5A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE

(Mycoplana
ramosa) 		PF00850
(Hist_deacetyl) 		4 SER A 280
PHE A 214
ILE A 191
GLY A 199
 None
 0.99A 2y7kA-3q9cA:
undetectable		 2y7kA-3q9cA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r11 ENZYME OF ENOLASE
SUPERFAMILY

(Francisella
philomiragia) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PRO A  51
SER A  33
ILE A  31
GLY A 304
 None
 0.69A 2y7kA-3r11A:
undetectable		 2y7kA-3r11A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6m YEAZ, RESUSCITATION
PROMOTING FACTOR

(Vibrio
parahaemolyticus) 		PF00814
(Peptidase_M22) 		4 PRO A 190
ILE A 195
PRO A  66
GLY A  65
 None
 0.98A 2y7kA-3r6mA:
undetectable		 2y7kA-3r6mA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3red HYDROXYNITRILE LYASE

(Prunus mume) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 PRO A 492
ILE A 121
PRO A 366
GLY A 365
 None
 0.92A 2y7kA-3redA:
undetectable		 2y7kA-3redA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A

(Helicobacter
pylori) 		PF01144
(CoA_trans) 		4 SER A 159
ILE A 213
PRO A 206
GLY A 207
 None
 0.98A 2y7kA-3rrlA:
undetectable		 2y7kA-3rrlA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3so4 METHIONINE-ADENOSYLT
RANSFERASE

(Entamoeba
histolytica) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 PRO A 165
PHE A 237
PRO A 242
GLY A 241
 None
 0.98A 2y7kA-3so4A:
undetectable		 2y7kA-3so4A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus) 		PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C) 		4 PRO A  12
SER A  14
ILE A  10
GLY A 312
 None
 0.97A 2y7kA-3t05A:
undetectable		 2y7kA-3t05A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1i DOUBLE-STRAND BREAK
REPAIR PROTEIN
MRE11A

(Homo sapiens) 		PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind) 		4 PRO A  67
SER A  68
PHE A  37
GLY A  24
 None
 0.91A 2y7kA-3t1iA:
undetectable		 2y7kA-3t1iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tnx PAPAIN

(Carica papaya) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 SER A  62
ILE A 255
PRO A 259
GLY A 258
 None
 0.99A 2y7kA-3tnxA:
undetectable		 2y7kA-3tnxA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3top MALTASE-GLUCOAMYLASE
, INTESTINAL

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 PRO A1514
SER A1516
ILE A1549
GLY A1168
 None
 0.72A 2y7kA-3topA:
undetectable		 2y7kA-3topA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uk8 CADMIUM-SPECIFIC
CARBONIC ANHYDRASE

(Conticribra
weissflogii) 		no annotation 4 PRO A 487
ILE A 470
PRO A 490
GLY A 492
 None
 0.97A 2y7kA-3uk8A:
undetectable		 2y7kA-3uk8A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3voc BETA/ALPHA-AMYLASE

(Paenibacillus
polymyxa) 		PF01373
(Glyco_hydro_14) 		4 PRO A 124
ILE A 260
PRO A 160
GLY A 159
 None
 0.94A 2y7kA-3vocA:
undetectable		 2y7kA-3vocA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3a V-TYPE ATP SYNTHASE
ALPHA CHAIN
V-TYPE ATP SYNTHASE
BETA CHAIN

(Thermus
thermophilus) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn) 		4 PRO A 352
ILE A 337
PRO D  17
GLY D  16
 None
 0.93A 2y7kA-3w3aA:
undetectable		 2y7kA-3w3aA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wd7 TYPE III POLYKETIDE
SYNTHASES ACRIDONE
SYNTHASE

(Citrus x
microcarpa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 PHE A 275
ILE A 309
PRO A 375
GLY A 374
 PHE  A 275 ( 1.3A)
ILE  A 309 ( 0.7A)
PRO  A 375 ( 1.1A)
GLY  A 374 ( 0.0A)
 0.92A 2y7kA-3wd7A:
undetectable		 2y7kA-3wd7A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9g CS6 FIMBRIAL SUBUNIT
B, CS6 FIMBRIAL
SUBUNIT A

(Escherichia
coli) 		PF16831
(CssAB) 		4 PRO A  56
PHE A  93
ILE A  54
GLY A  96
 None
 0.84A 2y7kA-4b9gA:
undetectable		 2y7kA-4b9gA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ee8 PRENYLTRANSFERASE

(Streptomyces
cinnamonensis) 		PF11468
(PTase_Orf2) 		4 PRO A  88
ILE A 164
PRO A 137
TRP A 225
 None
 1.00A 2y7kA-4ee8A:
undetectable		 2y7kA-4ee8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evq PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT

(Rhodopseudomonas
palustris) 		PF13458
(Peripla_BP_6) 		4 PRO A 208
PHE A 212
ILE A 205
GLY A 235
 ACT  A 405 (-4.5A)
None
None
None
 0.92A 2y7kA-4evqA:
2.3		 2y7kA-4evqA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fcx DNA REPAIR PROTEIN
RAD32

(Schizosaccharomyces
pombe) 		no annotation 4 PRO B  72
SER B  73
PHE B  42
GLY B  29
 None
 0.95A 2y7kA-4fcxB:
undetectable		 2y7kA-4fcxB:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsf PENICILLIN-BINDING
PROTEIN 3

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 PRO A 298
SER A 300
ILE A 354
PRO A 292
 None
 0.78A 2y7kA-4fsfA:
undetectable		 2y7kA-4fsfA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iig BETA-GLUCOSIDASE 1

(Aspergillus
aculeatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 PHE A 233
ILE A 244
PRO A 147
GLY A 146
 None
 0.88A 2y7kA-4iigA:
undetectable		 2y7kA-4iigA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jzy CRYPTOCHROME-1

(Drosophila
melanogaster) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 PHE A 161
ILE A 313
PRO A 143
TRP A 141
 None
 0.78A 2y7kA-4jzyA:
undetectable		 2y7kA-4jzyA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8j L-CARNITINE/GAMMA-BU
TYROBETAINE
ANTIPORTER

(Proteus
mirabilis) 		PF02028
(BCCT) 		4 PHE A 152
ILE A 495
GLY A  65
TRP A  68
 None
 0.88A 2y7kA-4m8jA:
undetectable		 2y7kA-4m8jA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mz0 CURL

(Moorea
producens) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 PRO A 335
SER A 337
ILE A 443
GLY A 332
 None
 0.95A 2y7kA-4mz0A:
undetectable		 2y7kA-4mz0A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oku MICRONEMAL PROTEIN
MIC2

(Toxoplasma
gondii) 		PF00090
(TSP_1)
PF00092
(VWA) 		4 PRO A 180
ILE A 210
PRO A 303
GLY A 304
 None
 0.99A 2y7kA-4okuA:
undetectable		 2y7kA-4okuA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pkv LETHAL FACTOR

(Bacillus
anthracis) 		PF07737
(ATLF)
PF09156
(Anthrax-tox_M) 		4 SER A 598
ILE A 602
PRO A 671
GLY A 670
 None
 0.92A 2y7kA-4pkvA:
undetectable		 2y7kA-4pkvA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromonas
sp. SM9913) 		no annotation 4 PRO H 339
SER H 336
PHE H 444
ILE H 337
 None
 0.87A 2y7kA-4qfkH:
4.7		 2y7kA-4qfkH:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmh LP04448P

(Drosophila
melanogaster) 		PF12348
(CLASP_N) 		4 PHE A 978
ILE A 983
PRO A1007
TRP A1001
 None
 0.97A 2y7kA-4qmhA:
undetectable		 2y7kA-4qmhA:
22.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rns PCP DEGRADATION
TRANSCRIPTIONAL
ACTIVATION PROTEIN

(Sphingobium
chlorophenolicum) 		PF03466
(LysR_substrate) 		6 PRO A  92
SER A  95
PHE A  99
PRO A 287
GLY A 288
TRP A 291
 None
 0.36A 2y7kA-4rnsA:
25.9		 2y7kA-4rnsA:
32.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4to8 FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE,
CLASS II

(Staphylococcus
aureus) 		PF01116
(F_bP_aldolase) 		4 PRO A  44
SER A  38
ILE A 276
GLY A  21
 None
 0.99A 2y7kA-4to8A:
undetectable		 2y7kA-4to8A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xn3 TAIL SPIKE PROTEIN

(Salmonella
virus HK620) 		no annotation 4 PRO A 252
SER A 255
GLY A 289
TRP A 314
 None
None
None
NAG  A1004 (-4.6A)
 0.95A 2y7kA-4xn3A:
undetectable		 2y7kA-4xn3A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwl EXOGLUCANASE S

(Clostridium
cellulovorans) 		PF02011
(Glyco_hydro_48) 		4 PRO A  91
SER A  92
PRO A  85
GLY A  86
 None
None
None
PGE  A 707 ( 4.5A)
 0.83A 2y7kA-4xwlA:
undetectable		 2y7kA-4xwlA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj5 PYRUVATE KINASE PKM

(Homo sapiens) 		PF00224
(PK)
PF02887
(PK_C) 		4 PRO A  53
SER A  55
ILE A  51
GLY A 363
 None
 0.99A 2y7kA-4yj5A:
undetectable		 2y7kA-4yj5A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c41 RIBOKINASE

(Homo sapiens) 		PF00294
(PfkB) 		4 PRO A 157
SER A 160
PHE A 176
PRO A 180
 None
 0.90A 2y7kA-5c41A:
undetectable		 2y7kA-5c41A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Rattus
norvegicus) 		PF00431
(CUB)
PF14670
(FXa_inhibition) 		4 PRO A 246
ILE A 249
PRO A 239
GLY A 238
 None
 0.95A 2y7kA-5ckqA:
undetectable		 2y7kA-5ckqA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dpd PROTEIN LYSINE
METHYLTRANSFERASE 1

(Rickettsia
prowazekii) 		PF10119
(MethyTransf_Reg)
PF13847
(Methyltransf_31) 		4 PRO A  88
PHE A 125
ILE A 123
GLY A  83
 None
 0.78A 2y7kA-5dpdA:
undetectable		 2y7kA-5dpdA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dwm PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE

(Brucella ovis) 		PF13420
(Acetyltransf_4) 		4 PRO A 177
SER A 179
PRO A 173
GLY A 174
 None
 0.99A 2y7kA-5dwmA:
undetectable		 2y7kA-5dwmA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gan PRE-MRNA-PROCESSING
FACTOR 31

(Saccharomyces
cerevisiae) 		PF01798
(Nop)
PF09785
(Prp31_C) 		4 PRO F  48
SER F  50
ILE F 101
PRO F  43
 None
 0.91A 2y7kA-5ganF:
undetectable		 2y7kA-5ganF:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		4 PRO A4380
ILE A4372
PRO A4403
GLY A4404
 None
 0.99A 2y7kA-5iicA:
7.6		 2y7kA-5iicA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens) 		PF01039
(Carboxyl_trans) 		4 PRO A 382
ILE A 391
PRO A 378
GLY A 379
 None
 0.97A 2y7kA-5infA:
undetectable		 2y7kA-5infA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 PRO A 200
ILE A 181
PRO A 592
GLY A 202
 None
 0.91A 2y7kA-5ipwA:
2.3		 2y7kA-5ipwA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuc PLATELET BINDING
PROTEIN GSPB

(Streptococcus
gordonii) 		no annotation 4 PRO A 474
ILE A 520
GLY A 450
TRP A 453
 None
None
SIA  A 602 ( 4.1A)
None
 0.91A 2y7kA-5iucA:
undetectable		 2y7kA-5iucA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B

(Escherichia
coli) 		PF01569
(PAP2) 		4 PRO A  31
ILE A 143
PRO A 105
TRP A 109
 None
 0.91A 2y7kA-5jwyA:
undetectable		 2y7kA-5jwyA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k2y PROBABLE PERIPLASMIC
SUGAR-BINDING
LIPOPROTEIN USPC

(Mycobacterium
tuberculosis) 		PF01547
(SBP_bac_1) 		4 PRO A 141
ILE A 116
GLY A 346
TRP A 123
 None
 0.90A 2y7kA-5k2yA:
6.0		 2y7kA-5k2yA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kiq PLATELET-BINDING
GLYCOPROTEIN

(Streptococcus
sanguinis) 		no annotation 4 PHE A 273
ILE A 366
GLY A 328
TRP A 302
 None
 0.97A 2y7kA-5kiqA:
undetectable		 2y7kA-5kiqA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mvo FOXE

(Rhodobacter sp.
SW2) 		no annotation 5 PRO A 125
SER A 128
ILE A 131
PRO A 164
GLY A 163
 None
 1.28A 2y7kA-5mvoA:
undetectable		 2y7kA-5mvoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohs -

(-) 		no annotation 4 SER A 457
ILE A 146
PRO A 136
GLY A 137
 None
 0.94A 2y7kA-5ohsA:
undetectable		 2y7kA-5ohsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5or7 CAPSID PROTEIN
CMRF35-LIKE MOLECULE
1

(Mus musculus;
Norwalk virus) 		no annotation 4 PRO A 361
SER C  43
ILE A 358
GLY A 400
 NA  A 601 (-4.6A)
None
None
None
 0.96A 2y7kA-5or7A:
undetectable		 2y7kA-5or7A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zc2 -

(-) 		no annotation 4 SER B  68
PHE B  74
ILE B  64
GLY B  44
 FMN  B 401 (-2.2A)
None
FMN  B 401 (-4.4A)
None
 0.97A 2y7kA-5zc2B:
undetectable		 2y7kA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zh5 LYSINE--TRNA LIGASE

(Plasmodium
falciparum) 		no annotation 4 PRO A 418
ILE A 474
PRO A 486
GLY A 487
 None
 0.87A 2y7kA-5zh5A:
undetectable		 2y7kA-5zh5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
HELICASE, CAS3
FAMILY

(Thermobifida
fusca) 		no annotation 4 SER G 536
PRO G 520
GLY G 521
TRP G 522
 None
 0.98A 2y7kA-6c66G:
undetectable		 2y7kA-6c66G:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARC

(Acetobacterium
woodii) 		no annotation 4 SER C  67
ILE C  10
PRO C  55
GLY C  62
 None
 0.99A 2y7kA-6fahC:
undetectable		 2y7kA-6fahC:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhw GLUCOAMYLASE P

(Amorphotheca
resinae) 		no annotation 4 SER A 304
PHE A 215
ILE A 261
GLY A 281
 None
 0.96A 2y7kA-6fhwA:
undetectable		 2y7kA-6fhwA:
17.00