SIMILAR PATTERNS OF AMINO ACIDS FOR 2Y7H_B_SAMB530_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bev BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4
BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4

(Enterovirus E;
Enterovirus E) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 TYR 3 106
GLU 1  68
THR 3  16
 None
 0.78A 2y7hB-1bev3:
undetectable		 2y7hB-1bev3:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bou 4,5-DIOXYGENASE
ALPHA CHAIN
4,5-DIOXYGENASE BETA
CHAIN

(Sphingomonas
paucimobilis;
Sphingomonas
paucimobilis) 		PF07746
(LigA)
PF02900
(LigB) 		3 TYR A  90
GLU B 242
THR B 271
 None
FE  B 501 ( 2.4A)
None
 0.88A 2y7hB-1bouA:
undetectable		 2y7hB-1bouA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpn CIRCULARLY PERMUTED

(Paenibacillus
macerans) 		PF00722
(Glyco_hydro_16) 		3 TYR A 166
GLU A 162
THR A   9
 None
 1.02A 2y7hB-1cpnA:
undetectable		 2y7hB-1cpnA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpt CYTOCHROME P450-TERP

(Pseudomonas sp.) 		PF00067
(p450) 		3 TYR A 160
GLU A 177
THR A 184
 None
 1.03A 2y7hB-1cptA:
undetectable		 2y7hB-1cptA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ej6 LAMBDA1

(Reovirus sp.) 		no annotation 3 TYR B 407
GLU B 452
THR B 376
 None
 0.97A 2y7hB-1ej6B:
0.0		 2y7hB-1ej6B:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f4h BETA-GALACTOSIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 TYR A 642
GLU A 650
THR A 706
 None
 0.78A 2y7hB-1f4hA:
0.9		 2y7hB-1f4hA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ig0 THIAMIN
PYROPHOSPHOKINASE

(Saccharomyces
cerevisiae) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		3 TYR A 207
GLU A 258
THR A 300
 None
 1.03A 2y7hB-1ig0A:
2.2		 2y7hB-1ig0A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iom CITRATE SYNTHASE

(Thermus
thermophilus) 		PF00285
(Citrate_synt) 		3 TYR A  30
GLU A 347
THR A 190
 None
 1.01A 2y7hB-1iomA:
undetectable		 2y7hB-1iomA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mrd IGG2B-KAPPA JEL103
FAB (HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H 147
GLU H 150
THR H 173
 None
 1.04A 2y7hB-1mrdH:
undetectable		 2y7hB-1mrdH:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8k EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2
SUBUNIT 1

(Homo sapiens) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		3 TYR A 120
GLU A 171
THR A 133
 None
 1.01A 2y7hB-1q8kA:
undetectable		 2y7hB-1q8kA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		3 TYR A 573
GLU A 628
THR A 310
 ACR  A3000 (-3.7A)
None
None
 0.94A 2y7hB-1ulvA:
undetectable		 2y7hB-1ulvA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vfd LACTOFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		3 TYR A 192
GLU A 121
THR A  58
 CO3  A 401 (-3.8A)
CO3  A 401 ( 3.7A)
None
 0.98A 2y7hB-1vfdA:
undetectable		 2y7hB-1vfdA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp4 AMINOTRANSFERASE,
PUTATIVE

(Thermotoga
maritima) 		PF00155
(Aminotran_1_2) 		3 TYR A  90
GLU A 214
THR A 192
 None
None
FMT  A 608 (-4.7A)
 0.91A 2y7hB-1vp4A:
2.5		 2y7hB-1vp4A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyt GLYCINE
DEHYDROGENASE
(DECARBOXYLATING)
SUBUNIT 1
GLYCINE
DEHYDROGENASE
SUBUNIT 2
(P-PROTEIN)

(Thermus
thermophilus;
Thermus
thermophilus) 		PF02347
(GDC-P)
PF02347
(GDC-P) 		3 TYR B 321
GLU A 162
THR A 402
 None
 0.90A 2y7hB-1wytB:
undetectable		 2y7hB-1wytB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE, A
SUBUNIT
PARTICULATE METHANE
MONOOXYGENASE
SUBUNIT C2

(Methylococcus
capsulatus;
Methylococcus
capsulatus) 		PF02461
(AMO)
PF04896
(AmoC) 		3 TYR C 151
GLU C  69
THR B 112
 None
 0.69A 2y7hB-1yewC:
undetectable		 2y7hB-1yewC:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z72 TRANSCRIPTIONAL
REGULATOR, PUTATIVE

(Streptococcus
pneumoniae) 		PF03070
(TENA_THI-4) 		3 TYR A 149
GLU A 212
THR A 119
 ACY  A 801 (-3.8A)
ACY  A 801 (-2.7A)
None
 1.04A 2y7hB-1z72A:
undetectable		 2y7hB-1z72A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfo GLUTAMYL-TRNA
SYNTHETASE

(Synechococcus
elongatus) 		PF00749
(tRNA-synt_1c) 		3 TYR A 192
GLU A  42
THR A  19
 GLU  A1486 (-4.9A)
GLU  A1486 ( 4.9A)
None
 0.86A 2y7hB-2cfoA:
undetectable		 2y7hB-2cfoA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2chr CHLOROMUCONATE
CYCLOISOMERASE

(Cupriavidus
necator) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 TYR A 294
GLU A 220
THR A 137
 None
MN  A 400 (-2.9A)
None
 1.03A 2y7hB-2chrA:
undetectable		 2y7hB-2chrA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE

(Candida
albicans) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		3 TYR A 346
GLU A 484
THR A  26
 NG1  A 901 ( 3.6A)
None
NG1  A 901 (-4.8A)
 1.03A 2y7hB-2dkdA:
undetectable		 2y7hB-2dkdA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgq OUTER MEMBRANE PORIN
PROTEIN 32

(Delftia
acidovorans) 		PF13609
(Porin_4) 		3 TYR X 171
GLU X 205
THR X 102
 None
None
MLT  X 700 (-2.9A)
 0.83A 2y7hB-2fgqX:
undetectable		 2y7hB-2fgqX:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0w LMO2234 PROTEIN

(Listeria
monocytogenes) 		PF01261
(AP_endonuc_2) 		3 TYR A  18
GLU A  76
THR A  79
 None
 0.98A 2y7hB-2g0wA:
undetectable		 2y7hB-2g0wA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1

(Thermotoga
maritima) 		PF02127
(Peptidase_M18) 		3 TYR A 121
GLU A 228
THR A  38
 None
 1.00A 2y7hB-2glfA:
undetectable		 2y7hB-2glfA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gtt NUCLEOPROTEIN

(Rabies
lyssavirus) 		PF00945
(Rhabdo_ncap) 		3 TYR A 259
GLU A 255
THR A 354
 None
 1.03A 2y7hB-2gttA:
undetectable		 2y7hB-2gttA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h7w CHAGASIN

(Trypanosoma
cruzi) 		PF09394
(Inhibitor_I42) 		3 TYR A  37
GLU A  71
THR A  32
 None
 0.89A 2y7hB-2h7wA:
2.8		 2y7hB-2h7wA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		3 TYR A 229
GLU A 245
THR A 381
 None
 1.04A 2y7hB-2pncA:
undetectable		 2y7hB-2pncA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7e COAGULATION FACTOR
VIII

(Homo sapiens) 		PF00754
(F5_F8_type_C)
PF07731
(Cu-oxidase_2) 		3 TYR B1762
GLU B1875
THR B1985
 None
 1.04A 2y7hB-2r7eB:
undetectable		 2y7hB-2r7eB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uvf EXOPOLYGALACTURONASE

(Yersinia
enterocolitica) 		PF00295
(Glyco_hydro_28)
PF12708
(Pectate_lyase_3) 		3 TYR A 233
GLU A 361
THR A 335
 None
 0.62A 2y7hB-2uvfA:
undetectable		 2y7hB-2uvfA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vu5 NUCLEOSIDE
DIPHOSPHATE KINASE

(Bacillus
anthracis) 		PF00334
(NDK) 		3 TYR A 148
GLU A  78
THR A  83
 None
 0.98A 2y7hB-2vu5A:
1.5		 2y7hB-2vu5A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus;
Chikungunya
virus) 		PF01589
(Alpha_E1_glycop)
PF00943
(Alpha_E2_glycop) 		3 TYR B 220
GLU B 229
THR A 116
 None
 0.87A 2y7hB-2xfbB:
undetectable		 2y7hB-2xfbB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8n 4-HYDROXYPHENYLACETA
TE DECARBOXYLASE
LARGE SUBUNIT

(Clostridium
scatologenes) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 TYR A  44
GLU A 880
THR A 404
 None
 1.03A 2y7hB-2y8nA:
undetectable		 2y7hB-2y8nA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3alx HEMAGGLUTININ,LINKER
,CDW150

(Saguinus
oedipus;
Measles
morbillivirus;
synthetic
construct) 		PF00423
(HN)
PF06214
(SLAM) 		3 TYR A 541
GLU A  75
THR A 121
 None
 0.91A 2y7hB-3alxA:
undetectable		 2y7hB-3alxA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daq DIHYDRODIPICOLINATE
SYNTHASE

(Staphylococcus
aureus) 		PF00701
(DHDPS) 		3 TYR A 171
GLU A 146
THR A 106
 None
 1.02A 2y7hB-3daqA:
undetectable		 2y7hB-3daqA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebj POLYMERASE ACIDIC
PROTEIN

(Influenza A
virus) 		PF00603
(Flu_PA) 		3 TYR A 130
GLU A 195
THR A  40
 None
 0.84A 2y7hB-3ebjA:
undetectable		 2y7hB-3ebjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE

(Bacteroides
vulgatus) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		3 TYR A 742
GLU A 545
THR A 497
 None
 0.96A 2y7hB-3gm8A:
undetectable		 2y7hB-3gm8A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzs UNCHARACTERIZED SUSD
SUPERFAMILY PROTEIN

(Bacteroides
fragilis) 		PF12741
(SusD-like) 		3 TYR A 495
GLU A 448
THR A 442
 None
 0.67A 2y7hB-3gzsA:
undetectable		 2y7hB-3gzsA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA

(Comamonas
testosteroni;
Comamonas
testosteroni) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
PF00866
(Ring_hydroxyl_B) 		3 TYR A  73
GLU B  66
THR B  60
 None
 0.99A 2y7hB-3gzyA:
undetectable		 2y7hB-3gzyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hlz UNCHARACTERIZED
PROTEIN BT_1490

(Bacteroides
thetaiotaomicron) 		PF12712
(DUF3805)
PF12713
(DUF3806) 		3 TYR A  17
GLU A  23
THR A 221
 None
 0.98A 2y7hB-3hlzA:
undetectable		 2y7hB-3hlzA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxw ALANYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01411
(tRNA-synt_2c) 		3 TYR A 331
GLU A 363
THR A 270
 None
 0.95A 2y7hB-3hxwA:
undetectable		 2y7hB-3hxwA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iib PEPTIDASE M28

(Shewanella
amazonensis) 		PF04389
(Peptidase_M28) 		3 TYR A 336
GLU A 343
THR A 317
 None
 0.96A 2y7hB-3iibA:
undetectable		 2y7hB-3iibA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermus
thermophilus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		3 TYR F 298
GLU F 289
THR F 172
 None
 1.01A 2y7hB-3kfuF:
undetectable		 2y7hB-3kfuF:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbh PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE

(Bacteroides
thetaiotaomicron) 		PF08543
(Phos_pyr_kin) 		3 TYR A 121
GLU A 148
THR A 227
 PXL  A 400 (-3.8A)
None
None
 0.97A 2y7hB-3mbhA:
2.6		 2y7hB-3mbhA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3na0 CHOLESTEROL
SIDE-CHAIN CLEAVAGE
ENZYME,
MITOCHONDRIAL

(Homo sapiens) 		PF00067
(p450) 		3 TYR A  89
GLU A  91
THR A  69
 None
 0.98A 2y7hB-3na0A:
undetectable		 2y7hB-3na0A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3na0 CHOLESTEROL
SIDE-CHAIN CLEAVAGE
ENZYME,
MITOCHONDRIAL

(Homo sapiens) 		PF00067
(p450) 		3 TYR A 100
GLU A  91
THR A  69
 None
 0.94A 2y7hB-3na0A:
undetectable		 2y7hB-3na0A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)

(Corynebacterium
glutamicum) 		PF01370
(Epimerase)
PF08338
(DUF1731) 		3 TYR A 124
GLU A 439
THR A 346
 None
 1.03A 2y7hB-3oh8A:
undetectable		 2y7hB-3oh8A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3a THIOSULFATE
SULFURTRANSFERASE

(Mycolicibacterium
thermoresistibile) 		PF00581
(Rhodanese) 		3 TYR A  73
GLU A 250
THR A 276
 None
 0.92A 2y7hB-3p3aA:
undetectable		 2y7hB-3p3aA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ra2 CAPSID PROTEIN

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		3 TYR A 733
GLU A 567
THR A 563
 None
 1.04A 2y7hB-3ra2A:
undetectable		 2y7hB-3ra2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ros NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Lactobacillus
acidophilus) 		PF00171
(Aldedh) 		3 TYR A  18
GLU A  73
THR A 167
 None
 0.99A 2y7hB-3rosA:
undetectable		 2y7hB-3rosA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shw TIGHT JUNCTION
PROTEIN ZO-1

(Homo sapiens) 		PF00595
(PDZ)
PF00625
(Guanylate_kin)
PF07653
(SH3_2) 		3 TYR A 722
GLU A 634
THR A 628
 None
 1.04A 2y7hB-3shwA:
undetectable		 2y7hB-3shwA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE

(Campylobacter
jejuni) 		PF04166
(PdxA) 		3 TYR A 340
GLU A  17
THR A 334
 None
 0.88A 2y7hB-3tsnA:
undetectable		 2y7hB-3tsnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B

(Bacillus
subtilis) 		PF12705
(PDDEXK_1) 		3 TYR B 169
GLU B 173
THR B 188
 None
 0.96A 2y7hB-3u44B:
undetectable		 2y7hB-3u44B:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w08 ALDOXIME DEHYDRATASE

(Pseudomonas
chlororaphis) 		PF13816
(Dehydratase_hem) 		3 TYR A 319
GLU A 321
THR A  78
 None
 0.86A 2y7hB-3w08A:
undetectable		 2y7hB-3w08A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsy SORTILIN-RELATED
RECEPTOR

(Homo sapiens) 		PF15901
(Sortilin_C)
PF15902
(Sortilin-Vps10) 		3 TYR A 141
GLU A 664
THR A 618
 None
None
NAG  A 804 (-4.0A)
 0.96A 2y7hB-3wsyA:
undetectable		 2y7hB-3wsyA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awm POLYMERASE PA

(Influenza A
virus) 		PF00603
(Flu_PA) 		3 TYR A 130
GLU A 195
THR A  40
 None
KDH  A 911 ( 4.9A)
None
 0.76A 2y7hB-4awmA:
undetectable		 2y7hB-4awmA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btg MAJOR INNER PROTEIN
P1

(Pseudomonas
virus phi6) 		no annotation 3 TYR A 532
GLU A 547
THR A 524
 None
 0.89A 2y7hB-4btgA:
1.1		 2y7hB-4btgA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c02 ACTIVIN RECEPTOR
TYPE-1

(Homo sapiens) 		PF00069
(Pkinase)
PF08515
(TGF_beta_GS) 		3 TYR A 292
GLU A 413
THR A 378
 None
None
FLC  A1504 ( 3.9A)
 1.04A 2y7hB-4c02A:
undetectable		 2y7hB-4c02A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccd GALACTOCEREBROSIDASE

(Mus musculus) 		PF02057
(Glyco_hydro_59)
PF17387
(Glyco_hydro_59M) 		3 TYR A 238
GLU A 182
THR A  93
 2DG  A1001 (-4.8A)
2DG  A1001 (-3.5A)
2DG  A1001 (-3.0A)
 0.69A 2y7hB-4ccdA:
undetectable		 2y7hB-4ccdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3h TOPOISOMERASE IV
SUBUNIT B, DNA
TOPOISOMERASE 4
SUBUNIT A CHIMERA

(Streptococcus
pneumoniae) 		PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
PF02518
(HATPase_c) 		3 TYR A1046
GLU A1151
THR A1148
 None
 0.95A 2y7hB-4i3hA:
2.2		 2y7hB-4i3hA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ja0 PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE

(Bombyx mori) 		PF00731
(AIRC)
PF01259
(SAICAR_synt) 		3 TYR A 233
GLU A  54
THR A  21
 None
None
SO4  A 505 (-3.6A)
 0.99A 2y7hB-4ja0A:
undetectable		 2y7hB-4ja0A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA

(Neisseria
gonorrhoeae) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA) 		3 TYR A 490
GLU A 534
THR A 573
 None
 0.96A 2y7hB-4k3bA:
undetectable		 2y7hB-4k3bA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9q BENZOYLFORMATE
DECARBOXYLASE

(Polynucleobacter
necessarius) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 TYR A 434
GLU A 372
THR A  84
 TPP  A 602 (-4.3A)
None
None
 1.00A 2y7hB-4k9qA:
undetectable		 2y7hB-4k9qA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krf PROTEIN ARGONAUTE-1

(Homo sapiens) 		PF02170
(PAZ)
PF02171
(Piwi)
PF08699
(ArgoL1)
PF16486
(ArgoN)
PF16487
(ArgoMid)
PF16488
(ArgoL2) 		3 TYR A 223
GLU A 259
THR A 355
 None
 1.04A 2y7hB-4krfA:
undetectable		 2y7hB-4krfA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5o POLYMERASE PA

(Influenza A
virus) 		PF00603
(Flu_PA) 		3 TYR A 130
GLU A 195
THR A  40
 None
 0.84A 2y7hB-4m5oA:
undetectable		 2y7hB-4m5oA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7o IRON-BINDING PROTEIN

(Staphylococcus
epidermidis) 		PF01497
(Peripla_BP_2) 		3 TYR A  71
GLU A 283
THR A 160
 None
 0.93A 2y7hB-4m7oA:
1.7		 2y7hB-4m7oA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfz POLYMERASE PA

(Influenza A
virus) 		PF00603
(Flu_PA) 		3 TYR A 130
GLU A 195
THR A  40
 None
 0.84A 2y7hB-4nfzA:
undetectable		 2y7hB-4nfzA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 TYR A 471
GLU A 463
THR A 162
 None
 0.96A 2y7hB-4p72A:
undetectable		 2y7hB-4p72A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pv6 N-TERMINAL
ACETYLTRANSFERASE
COMPLEX SUBUNIT
[ARD1]

(Thermoplasma
volcanium) 		no annotation 3 TYR C  70
GLU C 114
THR C 134
 None
 0.83A 2y7hB-4pv6C:
undetectable		 2y7hB-4pv6C:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8h PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Saccharomyces
cerevisiae) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		3 TYR A 879
GLU A 540
THR A 548
 None
 0.99A 2y7hB-4q8hA:
undetectable		 2y7hB-4q8hA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgk FATTY ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		3 TYR A 279
GLU A 280
THR A 240
 None
 0.92A 2y7hB-4qgkA:
undetectable		 2y7hB-4qgkA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0g UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 3 TYR A  30
GLU A  50
THR A 110
 None
 0.80A 2y7hB-4r0gA:
undetectable		 2y7hB-4r0gA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r30 LAFORIN

(Homo sapiens) 		PF00782
(DSPc) 		3 TYR A 208
GLU A 223
THR A 177
 None
 1.03A 2y7hB-4r30A:
undetectable		 2y7hB-4r30A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s1i PYRIDOXAL KINASE

(Entamoeba
histolytica) 		PF08543
(Phos_pyr_kin) 		3 TYR B 121
GLU B 146
THR B 221
 PLP  B 302 ( 4.0A)
MG  B 301 ( 3.9A)
None
 1.02A 2y7hB-4s1iB:
1.4		 2y7hB-4s1iB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB

(Brucella
abortus) 		PF00294
(PfkB) 		3 TYR A 139
GLU A   7
THR A  35
 None
 0.93A 2y7hB-4wjmA:
2.7		 2y7hB-4wjmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztx COBALAMIN-INDEPENDEN
T METHIONINE
SYNTHASE

(Neurospora
crassa) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		3 TYR A 503
GLU A 506
THR A 458
 None
 1.01A 2y7hB-4ztxA:
undetectable		 2y7hB-4ztxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 TYR A 962
GLU A1038
THR A 928
 None
EDO  A1603 (-3.3A)
None
 0.97A 2y7hB-5dotA:
2.5		 2y7hB-5dotA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 TYR A 715
GLU A 717
THR A 639
 None
 0.92A 2y7hB-5fr8A:
undetectable		 2y7hB-5fr8A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j90 RAGB/SUSD DOMAIN
PROTEIN

(Flavobacterium
johnsoniae) 		PF12741
(SusD-like) 		3 TYR A 112
GLU A 492
THR A 502
 None
 0.92A 2y7hB-5j90A:
undetectable		 2y7hB-5j90A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqm PROTEIN UPS1,
MITOCHONDRIAL,MITOCH
ONDRIAL DISTRIBUTION
AND MORPHOLOGY
PROTEIN 35

(Saccharomyces
cerevisiae) 		PF04707
(PRELI)
PF05254
(UPF0203) 		3 TYR A  94
GLU A 255
THR A 101
 None
 0.97A 2y7hB-5jqmA:
undetectable		 2y7hB-5jqmA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8d COAGULATION FACTOR
VIII,IG GAMMA-1
CHAIN C REGION

(Homo sapiens) 		PF00754
(F5_F8_type_C)
PF07731
(Cu-oxidase_2) 		3 TYR B1762
GLU B1875
THR B1985
 None
 0.79A 2y7hB-5k8dB:
undetectable		 2y7hB-5k8dB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbw RIBOFLAVIN
TRANSPORTER RIBU

(Thermotoga
maritima) 		PF12822
(ECF_trnsprt) 		3 TYR A  36
GLU A  40
THR A 112
 None
 1.00A 2y7hB-5kbwA:
undetectable		 2y7hB-5kbwA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		3 TYR A 284
GLU A 190
THR A 303
 None
GOL  A 601 (-4.3A)
GOL  A 601 ( 4.2A)
 0.78A 2y7hB-5kshA:
undetectable		 2y7hB-5kshA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		3 TYR A 509
GLU A 307
THR A 417
 None
 1.05A 2y7hB-5kshA:
undetectable		 2y7hB-5kshA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3h POLYMERASE ACIDIC
PROTEIN

(Influenza A
virus) 		PF00603
(Flu_PA) 		3 TYR A 453
GLU A 405
THR A 523
 None
 1.02A 2y7hB-5m3hA:
undetectable		 2y7hB-5m3hA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlq CDPS

(Nocardia
brasiliensis) 		no annotation 3 TYR A 194
GLU A 176
THR A 145
 None
 0.85A 2y7hB-5mlqA:
undetectable		 2y7hB-5mlqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msw THIOESTER REDUCTASE
DOMAIN-CONTAINING
PROTEIN

(Segniliparus
rugosus) 		PF00501
(AMP-binding)
PF00550
(PP-binding) 		3 TYR A 264
GLU A 169
THR A 492
 None
 0.99A 2y7hB-5mswA:
undetectable		 2y7hB-5mswA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 TYR A 706
GLU A 708
THR A 609
 None
 0.96A 2y7hB-5mzsA:
undetectable		 2y7hB-5mzsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 TYR A 706
GLU A 708
THR A 629
 None
 1.02A 2y7hB-5mzsA:
undetectable		 2y7hB-5mzsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n05 AUXILIARY ACTIVITY 9

(Lentinus
similis) 		PF03443
(Glyco_hydro_61) 		3 TYR A  85
GLU A 142
THR A 195
 None
 1.01A 2y7hB-5n05A:
undetectable		 2y7hB-5n05A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo sapiens) 		no annotation 3 TYR B  51
GLU B  53
THR B 186
 None
 0.98A 2y7hB-5ofbB:
undetectable		 2y7hB-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogx CYTOCHROME P450
REDUCTASE

(Amycolatopsis
methanolica) 		no annotation 3 TYR A 133
GLU A 328
THR A  42
 FAD  A 401 ( 3.8A)
FAD  A 401 ( 4.0A)
None
 0.87A 2y7hB-5ogxA:
1.7		 2y7hB-5ogxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osn CAPSID PROTEIN
CAPSID PROTEIN

(Enterovirus E;
Enterovirus E) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 TYR C 106
GLU A  63
THR C  16
 None
 0.80A 2y7hB-5osnC:
undetectable		 2y7hB-5osnC:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t13 CYANURIC ACID
AMIDOHYDROLASE

(Enterobacter
cloacae) 		PF09663
(Amido_AtzD_TrzD) 		3 TYR A 223
GLU A 303
THR A 232
 None
MG  A 403 (-3.4A)
None
 0.78A 2y7hB-5t13A:
undetectable		 2y7hB-5t13A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 3 TYR A 110
GLU A 276
THR A 270
 None
 0.90A 2y7hB-5ukgA:
undetectable		 2y7hB-5ukgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usd PEPTIDASE S66

(Bacillus
anthracis) 		PF02016
(Peptidase_S66) 		3 TYR A 244
GLU A 229
THR A 114
 None
 0.94A 2y7hB-5usdA:
undetectable		 2y7hB-5usdA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm9 PROTEIN ARGONAUTE-3

(Homo sapiens) 		no annotation 3 TYR A 226
GLU A 262
THR A 358
 None
 0.87A 2y7hB-5vm9A:
undetectable		 2y7hB-5vm9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsq NUCLEOPROTEIN

(Marburg
marburgvirus) 		PF05505
(Ebola_NP) 		3 TYR A 306
GLU A 242
THR A 236
 None
 1.00A 2y7hB-5xsqA:
undetectable		 2y7hB-5xsqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtb NADH-UBIQUINONE
OXIDOREDUCTASE 75
KDA SUBUNIT,
MITOCHONDRIAL

(Homo sapiens) 		PF00384
(Molybdopterin)
PF09326
(NADH_dhqG_C)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4) 		3 TYR M 589
GLU M 591
THR M 265
 None
 0.89A 2y7hB-5xtbM:
undetectable		 2y7hB-5xtbM:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhn METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER WITH
PHYTOCHROME SENSOR

(Nostoc
punctiforme) 		no annotation 3 TYR A 718
GLU A 637
THR A 653
 None
 0.72A 2y7hB-6bhnA:
undetectable		 2y7hB-6bhnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d4j PROTEIN PATCHED
HOMOLOG 1

(Homo sapiens) 		no annotation 3 TYR A1013
GLU A 126
THR A 143
 None
 1.02A 2y7hB-6d4jA:
undetectable		 2y7hB-6d4jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d4j PROTEIN PATCHED
HOMOLOG 1

(Homo sapiens) 		no annotation 3 TYR A1013
GLU A 126
THR A 368
 None
 0.87A 2y7hB-6d4jA:
undetectable		 2y7hB-6d4jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6evj RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT

(Influenza A
virus) 		no annotation 3 TYR B 555
GLU B 608
THR B 662
 None
 1.04A 2y7hB-6evjB:
undetectable		 2y7hB-6evjB:
undetectable