SIMILAR PATTERNS OF AMINO ACIDS FOR 2XN5_A_FUNA1356_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1914 | SIGNAL RECOGNITIONPARTICLE 9/14 FUSIONPROTEIN (Mus musculus) |
PF02290(SRP14)PF05486(SRP9-21) | 5 | SER A4011ALA A4014LEU A4038LEU A4029LEU A2087 | None | 1.01A | 2xn5A-1914A:0.0 | 2xn5A-1914A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cid | T CELL SURFACEGLYCOPROTEIN CD4 (Rattusnorvegicus) |
PF05790(C2-set)PF09191(CD4-extracel) | 5 | LEU A 66LEU A 72SER A 25LEU A 48LEU A 89 | None | 0.94A | 2xn5A-1cidA:0.0 | 2xn5A-1cidA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d1u | PROTEIN (REVERSETRANSCRIPTASE) (Murine leukemiavirus) |
PF00078(RVT_1) | 5 | ALA A 32GLN A 221LEU A 203LEU A 226LEU A 219 | None | 1.11A | 2xn5A-1d1uA:0.0 | 2xn5A-1d1uA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fy1 | HEPARIN-BINDINGPROTEIN (Homo sapiens) |
PF00089(Trypsin) | 5 | SER A 75SER A 74LEU A 30SER A 72LEU A 95 | None | 1.06A | 2xn5A-1fy1A:0.0 | 2xn5A-1fy1A:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8q | HYALURONATE LYASE (Streptococcusagalactiae) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | LEU A 323LEU A 354SER A 313LEU A 316LEU A 303 | None | 1.09A | 2xn5A-1i8qA:0.0 | 2xn5A-1i8qA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i9g | HYPOTHETICAL PROTEINRV2118C (Mycobacteriumtuberculosis) |
PF08704(GCD14)PF14801(GCD14_N) | 5 | SER A 171LEU A 177LEU A 199LEU A 193LEU A 186 | None | 1.02A | 2xn5A-1i9gA:0.1 | 2xn5A-1i9gA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfi | PHOSPHOGLUCOMUTASE 1 (Parameciumtetraurelia) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | SER A 354LEU A 344LEU A 389SER A 326LEU A 329 | None | 1.04A | 2xn5A-1kfiA:0.5 | 2xn5A-1kfiA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pq5 | TRYPSIN (Fusariumoxysporum) |
PF00089(Trypsin) | 5 | SER A 86SER A 85LEU A 45SER A 106LEU A 105 | None | 0.87A | 2xn5A-1pq5A:undetectable | 2xn5A-1pq5A:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q2l | PROTEASE III (Escherichiacoli) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF16187(Peptidase_M16_M) | 6 | SER A 98ALA A 148LEU A 111LEU A 131LEU A 145LEU A 138 | None | 1.38A | 2xn5A-1q2lA:0.0 | 2xn5A-1q2lA:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r9j | TRANSKETOLASE (Leishmaniamexicana) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | SER A 507LEU A 370SER A 506LEU A 505LEU A 360 | None | 1.12A | 2xn5A-1r9jA:undetectable | 2xn5A-1r9jA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sny | SNIFFER CG10964-PA (Drosophilamelanogaster) |
PF00106(adh_short) | 5 | SER A 153GLN A 222SER A 197LEU A 198ASN A 240 | None | 0.91A | 2xn5A-1snyA:undetectable | 2xn5A-1snyA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xks | NUCLEAR PORE COMPLEXPROTEIN NUP133 (Homo sapiens) |
no annotation | 5 | SER A 292SER A 291GLN A 228SER A 275LEU A 274 | None | 1.08A | 2xn5A-1xksA:undetectable | 2xn5A-1xksA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zuo | HYPOTHETICAL PROTEINLOC92912 (Homo sapiens) |
PF00179(UQ_con) | 5 | SER A 228LEU A 303LEU A 330LEU A 243LEU A 292 | None | 0.99A | 2xn5A-1zuoA:undetectable | 2xn5A-1zuoA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bv8 | C-PHYCOCYANIN ALPHASUBUNIT (Gracilariachilensis) |
PF00502(Phycobilisome) | 5 | LEU A 51LEU A 44SER A 143LEU A 142LEU A 154 | None | 0.77A | 2xn5A-2bv8A:undetectable | 2xn5A-2bv8A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d04 | NEOCULIN ACIDICSUBUNIT (Molinerialatifolia) |
PF01453(B_lectin) | 6 | SER A 18LEU A 31LEU A 54SER A 2LEU A 16LEU A 62 | None | 1.12A | 2xn5A-2d04A:undetectable | 2xn5A-2d04A:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ggq | 401AA LONGHYPOTHETICALGLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Sulfurisphaeratokodaii) |
PF00132(Hexapep)PF00483(NTP_transferase) | 5 | ALA A 8LEU A 171LEU A 184LEU A 6LEU A 163 | TTP A 500 (-3.5A)NoneNoneTTP A 500 (-4.0A)None | 1.10A | 2xn5A-2ggqA:undetectable | 2xn5A-2ggqA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i4c | BICARBONATETRANSPORTER (Synechocystissp. PCC 6803) |
PF13379(NMT1_2) | 5 | SER A 423LEU A 389SER A 367LEU A 370LEU A 444 | None | 1.09A | 2xn5A-2i4cA:undetectable | 2xn5A-2i4cA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kd0 | LRR REPEATS ANDUBIQUITIN-LIKEDOMAIN-CONTAININGPROTEIN AT2G30105 (Arabidopsisthaliana) |
PF00240(ubiquitin) | 5 | SER A 23LEU A 54LEU A 37LEU A 26LEU A 67 | None | 0.98A | 2xn5A-2kd0A:undetectable | 2xn5A-2kd0A:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2km8 | MRNA3'-END-PROCESSINGPROTEIN RNA15 (Saccharomycescerevisiae) |
PF00076(RRM_1) | 5 | SER B 79SER B 80ALA B 83LEU B 43ASN B 54 | None | 1.04A | 2xn5A-2km8B:undetectable | 2xn5A-2km8B:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p65 | HYPOTHETICAL PROTEINPF08_0063 (Plasmodiumfalciparum) |
PF00004(AAA) | 5 | SER A 88LEU A 107LEU A 144SER A 87LEU A 86 | None | 0.91A | 2xn5A-2p65A:undetectable | 2xn5A-2p65A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqd | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Agrobacteriumsp.) |
PF00275(EPSP_synthase) | 5 | LEU A 228LEU A 207SER A 42LEU A 234LEU A 182 | None | 1.10A | 2xn5A-2pqdA:undetectable | 2xn5A-2pqdA:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qq8 | TBC1 DOMAIN FAMILYMEMBER 14 (Homo sapiens) |
PF00566(RabGAP-TBC) | 5 | ALA A 641LEU A 580LEU A 634LEU A 610LYS A 609 | NoneNoneNoneUNX A 202 ( 4.2A)None | 1.06A | 2xn5A-2qq8A:undetectable | 2xn5A-2qq8A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | ALA A 616LEU A 495LEU A 622LEU A 582LEU A 734 | None | 1.00A | 2xn5A-2vdcA:undetectable | 2xn5A-2vdcA:12.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vos | FOLYLPOLYGLUTAMATESYNTHASE PROTEINFOLC (Mycobacteriumtuberculosis) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | SER A 310GLN A 277LEU A 293LEU A 279ASN A 303 | NoneNoneNoneNoneADP A1490 (-3.2A) | 1.11A | 2xn5A-2vosA:undetectable | 2xn5A-2vosA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxp | TRANSFORMING GROWTHFACTOR-BETA-INDUCEDPROTEIN IG-H3 (Homo sapiens) |
PF02469(Fasciclin) | 5 | ALA A 525LEU A 509LEU A 518LEU A 569LYS A 570 | None | 0.91A | 2xn5A-2vxpA:undetectable | 2xn5A-2vxpA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w2g | NON-STRUCTURALPROTEIN 3 (Severe acuterespiratorysyndrome-relatedcoronavirus) |
PF11633(SUD-M) | 5 | ALA A 503LEU A 412SER A 472LEU A 475LYS A 476 | None | 1.11A | 2xn5A-2w2gA:undetectable | 2xn5A-2w2gA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x5f | ASPARTATE_TYROSINE_PHENYLALANINEPYRIDOXAL-5'PHOSPHATE-DEPENDENTAMINOTRANSFERASE (Staphylococcusaureus) |
PF00155(Aminotran_1_2) | 5 | SER A 256LEU A 12LEU A 294LEU A 260LEU A 23 | None | 1.09A | 2xn5A-2x5fA:undetectable | 2xn5A-2x5fA:22.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 6 | GLN A 238LEU A 246LEU A 248SER A 265LEU A 269LEU A 276 | T44 A1370 (-3.3A)T44 A1370 (-4.6A)NoneNoneT44 A1370 (-4.0A)None | 1.18A | 2xn5A-2xn6A:53.6 | 2xn5A-2xn6A:99.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 8 | SER A 23ALA A 27GLN A 238LEU A 246LEU A 248LEU A 269ASN A 273LEU A 276 | T44 A1370 (-4.3A)T44 A1370 ( 3.9A)T44 A1370 (-3.3A)T44 A1370 (-4.6A)NoneT44 A1370 (-4.0A)T44 A1370 ( 3.3A)None | 0.95A | 2xn5A-2xn6A:53.6 | 2xn5A-2xn6A:99.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 10 | SER A 23SER A 24ALA A 27GLN A 238LEU A 246LEU A 248LEU A 269LYS A 270ASN A 273LEU A 276 | T44 A1370 (-4.3A)T44 A1370 ( 4.7A)T44 A1370 ( 3.9A)T44 A1370 (-3.3A)T44 A1370 (-4.6A)NoneT44 A1370 (-4.0A)T44 A1370 (-4.8A)T44 A1370 ( 3.3A)None | 0.48A | 2xn5A-2xn6A:53.6 | 2xn5A-2xn6A:99.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 10 | SER A 23SER A 24GLN A 238LEU A 246LEU A 248SER A 266LEU A 269LYS A 270ASN A 273LEU A 276 | T44 A1370 (-4.3A)T44 A1370 ( 4.7A)T44 A1370 (-3.3A)T44 A1370 (-4.6A)NoneT44 A1370 ( 4.1A)T44 A1370 (-4.0A)T44 A1370 (-4.8A)T44 A1370 ( 3.3A)None | 0.75A | 2xn5A-2xn6A:53.6 | 2xn5A-2xn6A:99.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 6 | SER A 24GLN A 238LEU A 248SER A 265LEU A 269LEU A 276 | T44 A1370 ( 4.7A)T44 A1370 (-3.3A)NoneNoneT44 A1370 (-4.0A)None | 1.25A | 2xn5A-2xn6A:53.6 | 2xn5A-2xn6A:99.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2d | CD180 ANTIGEN (Homo sapiens) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | LEU A 474LEU A 492SER A 460ASN A 479LEU A 503 | None | 0.95A | 2xn5A-3b2dA:undetectable | 2xn5A-3b2dA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg9 | PROTEIN OF UNIVERSALSTRESS PROTEIN USPAFAMILY (Lactobacillusplantarum) |
PF00582(Usp) | 5 | SER A 26SER A 27ALA A 30LEU A 141LEU A 120 | None | 1.02A | 2xn5A-3fg9A:undetectable | 2xn5A-3fg9A:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ij6 | UNCHARACTERIZEDMETAL-DEPENDENTHYDROLASE (Lactobacillusacidophilus) |
PF04909(Amidohydro_2) | 5 | ALA A 99LEU A 46LEU A 42SER A 86LEU A 88 | None | 1.05A | 2xn5A-3ij6A:undetectable | 2xn5A-3ij6A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR CWF10 (Schizosaccharomycespombe) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF03764(EFG_IV)PF16004(EFTUD2) | 5 | SER B 334SER B 333ALA B 336SER B 352LEU B 355 | None | 1.04A | 2xn5A-3jb9B:undetectable | 2xn5A-3jb9B:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jrp | FUSION PROTEIN OFPROTEIN TRANSPORTPROTEIN SEC13 ANDNUCLEOPORIN NUP145 (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | SER A 213ALA A 211LEU A 248SER A 261LEU A 269 | None | 1.08A | 2xn5A-3jrpA:undetectable | 2xn5A-3jrpA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jx9 | PUTATIVEPHOSPHOHEPTOSEISOMERASE (Exiguobacteriumsibiricum) |
PF10740(DUF2529) | 5 | GLN A 19LEU A 16SER A 146LEU A 149LEU A 125 | None | 1.07A | 2xn5A-3jx9A:undetectable | 2xn5A-3jx9A:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lnt | 2,3-BISPHOSPHOGLYCERATE-DEPENDENTPHOSPHOGLYCERATEMUTASE (Burkholderiapseudomallei) |
PF00300(His_Phos_1) | 5 | SER A 82LEU A 6LEU A 4SER A 166LEU A 193 | None | 1.09A | 2xn5A-3lntA:undetectable | 2xn5A-3lntA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nmz | APC VARIANT PROTEIN (Homo sapiens) |
PF00514(Arm) | 5 | SER A 624LEU A 616LEU A 585LYS A 586LEU A 592 | None | 1.09A | 2xn5A-3nmzA:undetectable | 2xn5A-3nmzA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ns5 | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT B (Saccharomycescerevisiae) |
PF00076(RRM_1) | 5 | LEU A 155LEU A 149LEU A 95LYS A 96LEU A 102 | None | 1.06A | 2xn5A-3ns5A:undetectable | 2xn5A-3ns5A:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q75 | FARNESYLTRANSFERASEBETA SUBUNIT (Cryptococcusneoformans) |
PF00432(Prenyltrans) | 5 | SER B 73SER B 72ALA B 71LEU B 415LEU B 102 | None | 1.06A | 2xn5A-3q75B:undetectable | 2xn5A-3q75B:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rh7 | HYPOTHETICALOXIDOREDUCTASE (Sinorhizobiummeliloti) |
PF01613(Flavin_Reduct) | 5 | SER A 270SER A 269SER A 195LEU A 196LEU A 210 | None | 1.05A | 2xn5A-3rh7A:undetectable | 2xn5A-3rh7A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rw7 | NUCLEAR RNA EXPORTFACTOR 1 (Homo sapiens) |
PF09162(Tap-RNA_bind) | 5 | SER A 305LEU A 320LEU A 280LYS A 311LEU A 315 | None | 1.02A | 2xn5A-3rw7A:undetectable | 2xn5A-3rw7A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1s | RESTRICTIONENDONUCLEASE BPUSI (Bacilluspumilus) |
PF02384(N6_Mtase)PF15516(BpuSI_N) | 5 | LEU A 621LEU A 668SER A 682LEU A 685LEU A 634 | None | 1.06A | 2xn5A-3s1sA:undetectable | 2xn5A-3s1sA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5r | TRANSCRIPTIONALREGULATOR TETRFAMILY (Syntrophusaciditrophicus) |
PF00440(TetR_N) | 5 | SER A 136LEU A 197SER A 154LEU A 157LEU A 164 | None | 0.85A | 2xn5A-3s5rA:undetectable | 2xn5A-3s5rA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t58 | SULFHYDRYL OXIDASE 1 (Mus musculus) |
PF00085(Thioredoxin)PF04777(Evr1_Alr) | 5 | ALA A 137LEU A 97LEU A 153LEU A 139LEU A 86 | None | 1.06A | 2xn5A-3t58A:undetectable | 2xn5A-3t58A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vil | BETA-GLUCOSIDASE (Neotermeskoshunensis) |
PF00232(Glyco_hydro_1) | 5 | SER A 445ALA A 39LEU A 131LEU A 135LEU A 94 | None | 1.11A | 2xn5A-3vilA:undetectable | 2xn5A-3vilA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpm | LATHERIN (Equus caballus) |
PF01273(LBP_BPI_CETP) | 5 | SER A 8LEU A 179LEU A 19LEU A 73LEU A 90 | None | 1.07A | 2xn5A-3zpmA:undetectable | 2xn5A-3zpmA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 5 | LEU A 57LEU A 31SER A 91LEU A 92LEU A 114 | None | 1.10A | 2xn5A-4aioA:undetectable | 2xn5A-4aioA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bb9 | GLUCOKINASEREGULATORY PROTEIN (Homo sapiens) |
no annotation | 5 | ALA A 287LEU A 245SER A 288LEU A 292LEU A 74 | None | 1.12A | 2xn5A-4bb9A:undetectable | 2xn5A-4bb9A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzj | PROTEIN TRANSPORTPROTEIN SEC13 (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | SER B 213ALA B 211LEU B 248SER B 261LEU B 269 | None | 1.06A | 2xn5A-4bzjB:undetectable | 2xn5A-4bzjB:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecl | SERINE RACEMASE (Enterococcusfaecalis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | SER A 355ALA A 353LEU A 245LEU A 247LEU A 368 | None | 0.91A | 2xn5A-4eclA:undetectable | 2xn5A-4eclA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ezg | PUTATIVEUNCHARACTERIZEDPROTEIN (Listeriamonocytogenes) |
no annotation | 5 | ALA A 106LEU A 121LEU A 99LEU A 87LEU A 115 | None | 1.06A | 2xn5A-4ezgA:undetectable | 2xn5A-4ezgA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0t | C-PHYCOCYANIN ALPHACHAIN (Synechocystissp. PCC 6803) |
PF00502(Phycobilisome) | 5 | LEU A 51LEU A 44SER A 145LEU A 144LEU A 166 | None | 1.00A | 2xn5A-4f0tA:undetectable | 2xn5A-4f0tA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fcg | UNCHARACTERIZEDPROTEIN (Xanthomonaseuvesicatoria) |
PF13855(LRR_8) | 5 | LEU A 356LEU A 333SER A 319LEU A 320LEU A 350 | None | 1.06A | 2xn5A-4fcgA:undetectable | 2xn5A-4fcgA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2c | DYP2 (Amycolatopsissp. ATCC 39116) |
no annotation | 5 | LEU A 11LEU A 32SER A 459LEU A 27LEU A 71 | None | 1.12A | 2xn5A-4g2cA:undetectable | 2xn5A-4g2cA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3w | HYPOTHETICAL PROTEIN (Parabacteroidesdistasonis) |
PF15414(DUF4621) | 5 | LEU A 215LEU A 123SER A 137LEU A 136LEU A 155 | MLY A 124 ( 4.7A)MLY A 124 ( 4.0A)NoneNoneNone | 1.03A | 2xn5A-4h3wA:undetectable | 2xn5A-4h3wA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hdj | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMB (Pseudomonasaeruginosa) |
PF13360(PQQ_2) | 6 | SER A 271SER A 272GLN A 217LEU A 264LEU A 257SER A 249 | None | 1.37A | 2xn5A-4hdjA:undetectable | 2xn5A-4hdjA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 12NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M)PF00662(Proton_antipo_N) | 5 | SER M 402ALA M 401LEU L 222SER M 398LEU L 211 | None | 1.08A | 2xn5A-4heaM:undetectable | 2xn5A-4heaM:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jmp | C-TERMINAL FRAGMENTOF CAPA, PROTEINTYROSINE KINASE (Staphylococcusaureus) |
PF01656(CbiA) | 5 | SER A1105SER A1099LEU A1074SER A1098LEU A1097 | None | 1.07A | 2xn5A-4jmpA:undetectable | 2xn5A-4jmpA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jmp | C-TERMINAL FRAGMENTOF CAPA, PROTEINTYROSINE KINASE (Staphylococcusaureus) |
PF01656(CbiA) | 5 | SER A1105SER A1099LEU A1147SER A1098LEU A1097 | None | 1.09A | 2xn5A-4jmpA:undetectable | 2xn5A-4jmpA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwg | TRNA(GUANINE(9)-N1)-METHYLTRANSFERASE (Schizosaccharomycespombe) |
PF01746(tRNA_m1G_MT) | 5 | SER A 187LEU A 194LEU A 252SER A 184LEU A 183 | None | 1.04A | 2xn5A-4jwgA:undetectable | 2xn5A-4jwgA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc5 | RHIE PROTEIN (Paraburkholderiarhizoxinica) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | SER A3231SER A3232LEU A3063LEU A3414LEU A3419 | None | 1.11A | 2xn5A-4kc5A:0.0 | 2xn5A-4kc5A:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc5 | RHIE PROTEIN (Paraburkholderiarhizoxinica) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | SER A3232ALA A3485LEU A3379SER A3477LEU A3395 | None | 1.09A | 2xn5A-4kc5A:0.0 | 2xn5A-4kc5A:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l3a | INTERNALIN K (Listeriamonocytogenes) |
no annotation | 5 | ALA A 113LEU A 128LEU A 106LEU A 94LEU A 122 | None | 1.08A | 2xn5A-4l3aA:undetectable | 2xn5A-4l3aA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ll6 | MYOSIN-4 (Saccharomycescerevisiae) |
PF01843(DIL) | 5 | LEU A1338LEU A1305LYS A1306ASN A1309LEU A1312 | None | 0.80A | 2xn5A-4ll6A:undetectable | 2xn5A-4ll6A:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ll8 | MYOSIN-4 (Saccharomycescerevisiae) |
PF01843(DIL) | 5 | LEU A1338LEU A1305LYS A1306ASN A1309LEU A1312 | None | 0.92A | 2xn5A-4ll8A:undetectable | 2xn5A-4ll8A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | ALA A 314LEU A 298LEU A 323SER A 312LEU A 311 | None | 1.10A | 2xn5A-4m7eA:undetectable | 2xn5A-4m7eA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nf2 | ORNITHINECARBAMOYLTRANSFERASE (Bacillusanthracis) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | SER A 170ALA A 174LEU A 9LEU A 28LEU A 140 | None | 1.00A | 2xn5A-4nf2A:undetectable | 2xn5A-4nf2A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4om9 | SERINE PROTEASE PET (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | SER A 455LEU A 388LEU A 414LEU A 431LYS A 430 | None | 1.11A | 2xn5A-4om9A:undetectable | 2xn5A-4om9A:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p8s | RETICULON-4RECEPTOR-LIKE 2 (Rattusnorvegicus) |
PF13855(LRR_8) | 5 | LEU A 111LEU A 87SER A 74LEU A 75LEU A 105 | None | 1.09A | 2xn5A-4p8sA:undetectable | 2xn5A-4p8sA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u09 | LIC12759 (Leptospirainterrogans) |
PF13855(LRR_8) | 5 | LEU A 276LEU A 253SER A 239LEU A 240LEU A 270 | None | 1.08A | 2xn5A-4u09A:undetectable | 2xn5A-4u09A:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xjx | HSDR (Escherichiacoli) |
PF04313(HSDR_N)PF04851(ResIII)PF12008(EcoR124_C) | 5 | LEU A 68LEU A 89SER A 58LEU A 61LEU A 159 | None | 1.09A | 2xn5A-4xjxA:undetectable | 2xn5A-4xjxA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yjj | ALPHA SUBUNIT OFCYANOBACTERIALPHYCOCYANINE PROTEIN (Phormidium) |
PF00502(Phycobilisome) | 5 | LEU A 51LEU A 44SER A 143LEU A 142LEU A 154 | None | 1.05A | 2xn5A-4yjjA:undetectable | 2xn5A-4yjjA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0c | TOLL-LIKE RECEPTOR13 (Mus musculus) |
PF00560(LRR_1)PF13516(LRR_6)PF13855(LRR_8) | 6 | SER A 276ALA A 277LEU A 342LEU A 308SER A 278LEU A 301 | NAG A 907 ( 4.6A)NoneNoneNoneNAG A 907 (-3.5A)None | 1.49A | 2xn5A-4z0cA:undetectable | 2xn5A-4z0cA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b58 | PUTATIVE HEMIN ABCTRANSPORT SYSTEM,MEMBRANE PROTEIN (Burkholderiacenocepacia) |
PF01032(FecCD) | 5 | SER A 120SER A 119LEU A 176LEU A 268LEU A 105 | None | 1.06A | 2xn5A-5b58A:undetectable | 2xn5A-5b58A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6g | AGR133CPSISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF10345(Cohesin_load)no annotation | 5 | ALA A 471LEU A 497LEU A 519SER B 20LEU B 27 | None | 1.06A | 2xn5A-5c6gA:undetectable | 2xn5A-5c6gA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed4 | RESPONSE REGULATOR (Mycobacteriumtuberculosis) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 5 | LEU A 136LEU A 132SER A 37LEU A 40LYS A 41 | None | 1.07A | 2xn5A-5ed4A:undetectable | 2xn5A-5ed4A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5emi | CELL WALLHYDROLASE/AUTOLYSIN (Nostocpunctiforme) |
PF01520(Amidase_3) | 5 | SER A 571LEU A 439LEU A 612SER A 574LEU A 477 | None | 0.95A | 2xn5A-5emiA:undetectable | 2xn5A-5emiA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5grq | DEATHDOMAIN-ASSOCIATEDPROTEIN 6 (Homo sapiens) |
PF03344(Daxx) | 5 | GLN A 77LEU A 73SER A 110LEU A 113LEU A 123 | None | 1.07A | 2xn5A-5grqA:undetectable | 2xn5A-5grqA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtj | DUAL SPECIFICITYPROTEIN PHOSPHATASE26 (Homo sapiens) |
PF00782(DSPc) | 5 | ALA A 94GLN A 131SER A 159LEU A 162LEU A 169 | NoneNonePO4 A 301 ( 4.1A)NoneNone | 0.82A | 2xn5A-5gtjA:undetectable | 2xn5A-5gtjA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gvv | GLYCOSYL TRANSFERASEFAMILY 8 (Streptococcuspneumoniae) |
PF01501(Glyco_transf_8) | 5 | LEU A 103LEU A 118SER A 191LEU A 192ASN A 197 | None | 0.96A | 2xn5A-5gvvA:undetectable | 2xn5A-5gvvA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hus | TREHALOSE SYNTHASEREGULATORY PROTEIN (Candidaalbicans) |
PF02358(Trehalose_PPase) | 6 | SER A 66LEU A 247LEU A 25SER A 61LEU A 60LEU A 300 | None | 1.44A | 2xn5A-5husA:undetectable | 2xn5A-5husA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irm | UNCHARACTERIZEDPROTEIN (Oryctolaguscuniculus) |
PF05729(NACHT)PF13516(LRR_6) | 5 | ALA A 399LEU A 386LEU A 328LEU A 356LEU A 316 | None | 1.00A | 2xn5A-5irmA:undetectable | 2xn5A-5irmA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irm | UNCHARACTERIZEDPROTEIN (Oryctolaguscuniculus) |
PF05729(NACHT)PF13516(LRR_6) | 5 | ALA A 819LEU A 858LEU A 856LEU A 846LEU A 871 | None | 1.02A | 2xn5A-5irmA:undetectable | 2xn5A-5irmA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjo | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF08238(Sel1) | 5 | ALA A 213LEU A 246LEU A 249SER A 214LEU A 268 | None | 1.08A | 2xn5A-5jjoA:undetectable | 2xn5A-5jjoA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5khn | RND TRANSPORTER (Burkholderiamultivorans) |
no annotation | 5 | SER B 391SER B 727ALA B 387LEU B 337LEU B 341 | None | 0.94A | 2xn5A-5khnB:undetectable | 2xn5A-5khnB:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lh9 | OMEGA TRANSAMINASE (Pseudomonas sp.) |
PF00202(Aminotran_3) | 5 | ALA A 118LEU A 93LEU A 97LEU A 282LEU A 336 | None | 1.12A | 2xn5A-5lh9A:undetectable | 2xn5A-5lh9A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp5 | RODSHAPE-DETERMININGPROTEIN (MREC) (Helicobacterpylori) |
PF04085(MreC) | 5 | SER C 111LEU C 243SER C 113LEU C 114LEU C 120 | None | 1.09A | 2xn5A-5lp5C:undetectable | 2xn5A-5lp5C:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv6 | TRANSFORMING GROWTHFACTOR-BETA-INDUCEDPROTEIN IG-H3 (Homo sapiens) |
PF02469(Fasciclin) | 5 | ALA A 525LEU A 509LEU A 518LEU A 569LYS A 570 | None | 0.89A | 2xn5A-5nv6A:undetectable | 2xn5A-5nv6A:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5w | INTERFERON LAMBDARECEPTOR 1 (Homo sapiens) |
PF01108(Tissue_fac) | 5 | ALA B 141LEU B 166LEU B 119SER B 177LEU B 176 | None | 1.04A | 2xn5A-5t5wB:undetectable | 2xn5A-5t5wB:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxn | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Pseudomonasaeruginosa) |
no annotation | 5 | ALA A 336LEU A 315LEU A 317SER A 296LEU A 299 | None | 0.94A | 2xn5A-5uxnA:undetectable | 2xn5A-5uxnA:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbf | HARMONIN (Homo sapiens) |
PF00595(PDZ) | 5 | LEU B 468LEU B 522SER B 463LYS B 488LEU B 535 | None | 1.07A | 2xn5A-5xbfB:undetectable | 2xn5A-5xbfB:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y92 | RECEPTOR-LIKEPROTEIN KINASEANXUR2 (Arabidopsisthaliana) |
no annotation | 5 | ALA A 407LEU A 102LEU A 104SER A 132LEU A 131 | None | 1.09A | 2xn5A-5y92A:undetectable | 2xn5A-5y92A:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq5 | OSTEOMODULIN (Homo sapiens) |
no annotation | 6 | LEU A 240LEU A 219SER A 201LEU A 203LYS A 204LEU A 231 | None | 1.47A | 2xn5A-5yq5A:undetectable | 2xn5A-5yq5A:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq5 | OSTEOMODULIN (Homo sapiens) |
no annotation | 5 | SER A 74SER A 75LEU A 140LEU A 96LEU A 146 | None | 1.07A | 2xn5A-5yq5A:undetectable | 2xn5A-5yq5A:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zln | TOLL-LIKE RECEPTOR 9 (Mus musculus) |
no annotation | 5 | LEU A 341LEU A 369SER A 365LEU A 366LEU A 356 | None | 1.08A | 2xn5A-5zlnA:undetectable | 2xn5A-5zlnA:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9m | SERINE PROTEASE (Planococcusplakortidis) |
no annotation | 5 | SER A 154ALA A 181LEU A 285LEU A 228SER A 251 | None | 1.11A | 2xn5A-6f9mA:undetectable | 2xn5A-6f9mA:12.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fsh | OXYB PROTEIN (Actinoplanesteichomyceticus) |
no annotation | 5 | ALA A 236LEU A 99LEU A 103LEU A 233LEU A 226 | HEM A 401 (-3.4A)NoneNoneHEM A 401 ( 4.4A)None | 1.11A | 2xn5A-6fshA:undetectable | 2xn5A-6fshA:11.98 |