SIMILAR PATTERNS OF AMINO ACIDS FOR 2XKW_A_P1BA1478_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6d | THERMOSOME (BETASUBUNIT) (Thermoplasmaacidophilum) |
PF00118(Cpn60_TCP1) | 4 | GLU B 270GLN B 300ALA B 306ILE B 308 | None | 0.80A | 2xkwA-1a6dB:0.2 | 2xkwA-1a6dB:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1chm | CREATINEAMIDINOHYDROLASE (Pseudomonasputida) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 4 | GLU A 144ILE A 40ALA A 114ILE A 76 | None | 0.84A | 2xkwA-1chmA:undetectable | 2xkwA-1chmA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d7w | MYELOPEROXIDASE (Homo sapiens) |
PF03098(An_peroxidase) | 4 | LEU C 572GLU C 263ILE C 283ILE A 10 | None | 0.64A | 2xkwA-1d7wC:0.0 | 2xkwA-1d7wC:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq1 | CYTOCHROME CD1NITRITE REDUCTASE (Paracoccuspantotrophus) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 4 | LEU A 181ILE A 223ALA A 260ILE A 238 | None | 0.85A | 2xkwA-1gq1A:0.0 | 2xkwA-1gq1A:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hlk | BETA-LACTAMASE, TYPEII (Bacteroidesfragilis) |
no annotation | 4 | LEU A 88ILE A 58ALA A 44ILE A 72 | None | 0.80A | 2xkwA-1hlkA:undetectable | 2xkwA-1hlkA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hlm | HEMOGLOBIN (CYANOMET) (Molpadiaarenicola) |
PF00042(Globin) | 5 | LEU A 12GLU A 16ILE A 20GLN A 26ALA A 127 | None | 1.42A | 2xkwA-1hlmA:undetectable | 2xkwA-1hlmA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hzv | NITRITE REDUCTASE (Pseudomonasaeruginosa) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 4 | LEU A 163ILE A 205ALA A 242ILE A 220 | None | 0.82A | 2xkwA-1hzvA:undetectable | 2xkwA-1hzvA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ivh | ISOVALERYL-COADEHYDROGENASE (Homo sapiens) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 55ILE A 86ALA A 375ILE A 332 | NoneNoneCOS A 400 (-4.8A)None | 0.71A | 2xkwA-1ivhA:0.0 | 2xkwA-1ivhA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqi | SHORT CHAIN ACYL-COADEHYDROGENASE (Rattusnorvegicus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 10ILE A 76ALA A 332ILE A 258 | None | 0.81A | 2xkwA-1jqiA:0.0 | 2xkwA-1jqiA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n61 | CARBON MONOXIDEDEHYDROGENASE MEDIUMCHAIN (Oligotrophacarboxidovorans) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 4 | LEU C 138GLU C 165ALA C 46ILE C 40 | None | 0.74A | 2xkwA-1n61C:0.0 | 2xkwA-1n61C:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nnl | L-3-PHOSPHOSERINEPHOSPHATASE (Homo sapiens) |
PF00702(Hydrolase) | 4 | LEU A 7GLU A 218ILE A 194ILE A 125 | None | 0.73A | 2xkwA-1nnlA:undetectable | 2xkwA-1nnlA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozh | ACETOLACTATESYNTHASE, CATABOLIC (Klebsiellapneumoniae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | LEU A 521GLU A 522ILE A 376ILE A 415 | None | 0.81A | 2xkwA-1ozhA:undetectable | 2xkwA-1ozhA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qc5 | PROTEIN (ALPHA1BETA1 INTEGRIN) (Homo sapiens) |
PF00092(VWA) | 4 | LEU B 452GLU B 488ILE B 416ILE B 521 | None | 0.78A | 2xkwA-1qc5B:undetectable | 2xkwA-1qc5B:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qst | TGCN5 HISTONE ACETYLTRANSFERASE (Tetrahymenathermophila) |
PF00583(Acetyltransf_1) | 4 | LEU A 49ILE A 107GLN A 76ILE A 85 | None | 0.73A | 2xkwA-1qstA:undetectable | 2xkwA-1qstA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rzm | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Thermotogamaritima) |
PF00793(DAHP_synth_1) | 4 | ILE A 183ARG A 208ALA A 254ILE A 258 | None | 0.85A | 2xkwA-1rzmA:undetectable | 2xkwA-1rzmA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uaa | PROTEIN(ATP-DEPENDENT DNAHELICASE REP.) (Escherichiacoli) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | LEU A 181ILE A 92ALA A 51ILE A 208 | None | 0.78A | 2xkwA-1uaaA:undetectable | 2xkwA-1uaaA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uek | 4-(CYTIDINE5'-DIPHOSPHO)-2C-METHYL-D-ERYTHRITOLKINASE (Thermusthermophilus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | LEU A 48ILE A 79GLN A 100ILE A 85 | None | 0.82A | 2xkwA-1uekA:undetectable | 2xkwA-1uekA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w27 | PHENYLALANINEAMMONIA-LYASE 1 (Petroselinumcrispum) |
PF00221(Lyase_aromatic) | 4 | GLU A 275ILE A 698ALA A 288ILE A 324 | None | 0.76A | 2xkwA-1w27A:undetectable | 2xkwA-1w27A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xi6 | EXTRAGENICSUPPRESSOR (Pyrococcusfuriosus) |
PF00459(Inositol_P) | 4 | LEU A 53ILE A 13ALA A 181ILE A 209 | None | 0.76A | 2xkwA-1xi6A:undetectable | 2xkwA-1xi6A:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xyz | 1,4-BETA-D-XYLAN-XYLANOHYDROLASE (Ruminiclostridiumthermocellum) |
PF00331(Glyco_hydro_10) | 4 | LEU A 583GLU A 587ILE A 637ILE A 749 | None | 0.62A | 2xkwA-1xyzA:undetectable | 2xkwA-1xyzA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ym5 | HYPOTHETICAL 32.6KDA PROTEIN INDAP2-SLT2 INTERGENICREGION (Saccharomycescerevisiae) |
PF02567(PhzC-PhzF) | 4 | GLU A 131ILE A 163ALA A 266ILE A 252 | None | 0.86A | 2xkwA-1ym5A:undetectable | 2xkwA-1ym5A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zrt | UBIQUINOL-CYTOCHROMEC REDUCTASEIRON-SULFUR SUBUNIT (Rhodobactercapsulatus) |
PF00355(Rieske)PF10399(UCR_Fe-S_N) | 4 | LEU E 190ILE E 74ALA E 85ILE E 82 | None | 0.81A | 2xkwA-1zrtE:undetectable | 2xkwA-1zrtE:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2acg | PROFILIN II (Acanthamoebacastellanii) |
PF00235(Profilin) | 4 | GLU A 61GLN A 18ALA A 109ILE A 104 | None | 0.69A | 2xkwA-2acgA:undetectable | 2xkwA-2acgA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfm | THERMOSTABLE DNALIGASE (Pyrococcusfuriosus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | GLU A 150ILE A 113GLN A 118ALA A 124 | None | 0.75A | 2xkwA-2cfmA:undetectable | 2xkwA-2cfmA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dg0 | DRP35 (Staphylococcusaureus) |
PF08450(SGL) | 4 | ILE A 266GLN A 268ALA A 34ILE A 296 | None | 0.77A | 2xkwA-2dg0A:undetectable | 2xkwA-2dg0A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e8y | AMYX PROTEIN (Bacillussubtilis) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | LEU A 634GLU A 632ILE A 658ALA A 615 | None | 0.79A | 2xkwA-2e8yA:undetectable | 2xkwA-2e8yA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f8l | HYPOTHETICAL PROTEINLMO1582 (Listeriamonocytogenes) |
PF02384(N6_Mtase) | 4 | LEU A 308ILE A 105GLN A 139ILE A 122 | None | 0.83A | 2xkwA-2f8lA:undetectable | 2xkwA-2f8lA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gjm | LACTOPEROXIDASE (Bubalus bubalis) |
PF03098(An_peroxidase) | 4 | LEU A 572ILE A 283ALA A 184ILE A 10 | None | 0.73A | 2xkwA-2gjmA:undetectable | 2xkwA-2gjmA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6r | TRIOSEPHOSPHATEISOMERASE (Methanocaldococcusjannaschii) |
PF00121(TIM) | 4 | GLU A 138GLN A 41ALA A 22ILE A 48 | None | 0.79A | 2xkwA-2h6rA:undetectable | 2xkwA-2h6rA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jh9 | VP4 CORE PROTEIN (Bluetonguevirus) |
PF05059(Orbi_VP4) | 4 | GLU A 192ILE A 248ALA A 356ILE A 319 | None | 0.79A | 2xkwA-2jh9A:undetectable | 2xkwA-2jh9A:18.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2p54 | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 4 | LEU A 247ILE A 272GLN A 277ILE A 317 | None735 A 469 ( 4.2A)735 A 469 (-4.4A)735 A 469 ( 4.8A) | 0.49A | 2xkwA-2p54A:37.1 | 2xkwA-2p54A:61.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qio | ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 4 | LEU A 233ILE A 188ALA A 215ILE A 211 | None | 0.81A | 2xkwA-2qioA:undetectable | 2xkwA-2qioA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v8n | LACTOSE PERMEASE (Escherichiacoli) |
PF01306(LacY_symp) | 4 | LEU A 216ILE A 349ALA A 291ILE A 283 | None | 0.78A | 2xkwA-2v8nA:undetectable | 2xkwA-2v8nA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 4 | ILE A 152GLN A 142ALA A 136ILE A 128 | None | 0.85A | 2xkwA-2v95A:undetectable | 2xkwA-2v95A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2was | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE (Saccharomycescerevisiae) |
PF01648(ACPS) | 4 | ILE B1796GLN B1802ALA B1878ILE B1776 | None | 0.70A | 2xkwA-2wasB:undetectable | 2xkwA-2wasB:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wdu | GLUTATHIONETRANSFERASE SIGMACLASS (Fasciolahepatica) |
PF14497(GST_C_3) | 4 | LEU A 78ILE A 20GLN A 35ILE A 44 | None | 0.81A | 2xkwA-2wduA:undetectable | 2xkwA-2wduA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y1h | PUTATIVEDEOXYRIBONUCLEASETATDN3 (Homo sapiens) |
PF01026(TatD_DNase) | 4 | LEU A 210GLU A 252ILE A 242ALA A 34 | None | 0.72A | 2xkwA-2y1hA:undetectable | 2xkwA-2y1hA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zts | PUTATIVEUNCHARACTERIZEDPROTEIN PH0186 (Pyrococcushorikoshii) |
PF06745(ATPase) | 4 | LEU A 161GLU A 195ILE A 147ILE A 96 | None | 0.82A | 2xkwA-2ztsA:undetectable | 2xkwA-2ztsA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zws | NEUTRAL CERAMIDASE (Pseudomonasaeruginosa) |
PF04734(Ceramidase_alk)PF17048(Ceramidse_alk_C) | 4 | LEU A 486GLU A 404ALA A 44ILE A 134 | None | 0.83A | 2xkwA-2zwsA:undetectable | 2xkwA-2zwsA:17.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b0q | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 7 | LEU A 255GLU A 259ILE A 281GLN A 286ARG A 288ALA A 292ILE A 326 | NoneNoneMC5 A 1 ( 4.8A)NoneNoneNoneMC5 A 1 ( 4.9A) | 0.24A | 2xkwA-3b0qA:42.6 | 2xkwA-3b0qA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm5 | SIGNAL RECOGNITION54 KDA PROTEIN (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 4 | ILE A 201GLN A 206ALA A 171ILE A 211 | None | 0.84A | 2xkwA-3dm5A:undetectable | 2xkwA-3dm5A:23.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 5 | LEU D 255ILE D 281GLN D 286ALA D 292ILE D 326 | NonePLB D 701 (-4.6A)NonePLB D 701 ( 4.1A)PLB D 701 ( 4.5A) | 0.68A | 2xkwA-3dzuD:37.5 | 2xkwA-3dzuD:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i5c | FUSION OF GENERALCONTROL PROTEIN GCN4AND WSPR RESPONSEREGULATOR PROTEIN (Pseudomonasaeruginosa;Saccharomycescerevisiae) |
PF00990(GGDEF) | 4 | LEU A 189ILE A 316GLN A 321ALA A 326 | None | 0.77A | 2xkwA-3i5cA:undetectable | 2xkwA-3i5cA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | LEU A 296ILE A 267GLN A 434ILE A 428 | None | 0.68A | 2xkwA-3ju8A:undetectable | 2xkwA-3ju8A:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kn5 | RIBOSOMAL PROTEIN S6KINASE ALPHA-5 (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 698GLU A 518ALA A 531ILE A 563 | None | 0.76A | 2xkwA-3kn5A:undetectable | 2xkwA-3kn5A:24.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lj0 | SERINE/THREONINE-PROTEINKINASE/ENDORIBONUCLEASE IRE1 (Saccharomycescerevisiae) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A) | 4 | LEU A 944ILE A 775GLN A 780ALA A 786 | None | 0.81A | 2xkwA-3lj0A:undetectable | 2xkwA-3lj0A:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mog | PROBABLE3-HYDROXYBUTYRYL-COADEHYDROGENASE (Escherichiacoli) |
PF00725(3HCDH)PF02737(3HCDH_N) | 5 | LEU A 372ILE A 344GLN A 326ALA A 395ILE A 441 | None | 1.47A | 2xkwA-3mogA:undetectable | 2xkwA-3mogA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n4t | APH(2'')-ID (Enterococcuscasseliflavus) |
PF01636(APH) | 4 | LEU A 233ILE A 203ALA A 36ILE A 44 | None | 0.85A | 2xkwA-3n4tA:undetectable | 2xkwA-3n4tA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nr1 | HD DOMAIN-CONTAININGPROTEIN 3 (Homo sapiens) |
PF13328(HD_4) | 4 | LEU A 164ILE A 42ALA A 15ILE A 33 | None | 0.81A | 2xkwA-3nr1A:undetectable | 2xkwA-3nr1A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oig | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Bacillussubtilis) |
PF13561(adh_short_C2) | 4 | LEU A 234ILE A 189ALA A 216ILE A 212 | None | 0.85A | 2xkwA-3oigA:undetectable | 2xkwA-3oigA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pg8 | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Thermotogamaritima) |
PF00793(DAHP_synth_1) | 4 | ILE A 183ARG A 208ALA A 254ILE A 258 | None | 0.85A | 2xkwA-3pg8A:undetectable | 2xkwA-3pg8A:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4d | POSSIBLECHLOROMUCONATECYCLOISOMERASEMANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY (Cytophagahutchinsonii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 23ILE A 54ALA A 250ILE A 278 | None | 0.76A | 2xkwA-3q4dA:undetectable | 2xkwA-3q4dA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qe3 | SORBITOLDEHYDROGENASE (Ovis aries) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 220GLN A 256ALA A 285ILE A 292 | None | 0.85A | 2xkwA-3qe3A:undetectable | 2xkwA-3qe3A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s8d | COENZYME ATRANSFERASE (Yersinia pestis) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | LEU A 406ILE A 418ARG A 378ALA A 371 | None | 0.82A | 2xkwA-3s8dA:undetectable | 2xkwA-3s8dA:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqk | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Francisellatularensis) |
PF00793(DAHP_synth_1) | 4 | LEU A 150GLU A 148ALA A 78ILE A 75 | NoneACT A1002 ( 4.6A)NoneNone | 0.81A | 2xkwA-3tqkA:undetectable | 2xkwA-3tqkA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u5t | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | GLU A 50ILE A 33ALA A 225ILE A 135 | None | 0.80A | 2xkwA-3u5tA:undetectable | 2xkwA-3u5tA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdb | PROBABLEATP-DEPENDENT CLPPROTEASE ATP-BINDINGSUBUNIT (Mycobacteriumtuberculosis) |
PF02861(Clp_N) | 4 | ILE A 67GLN A 62ARG A 60ILE A 38 | None | 0.69A | 2xkwA-3wdbA:undetectable | 2xkwA-3wdbA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3woh | SIAM (Streptomycessp. A7248) |
PF13561(adh_short_C2) | 4 | GLU A 55ILE A 38ALA A 229ILE A 142 | None | 0.78A | 2xkwA-3wohA:undetectable | 2xkwA-3wohA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3u | NADH:FLAVINOXIDOREDUCTASE/NADHOXIDASE (Zymomonasmobilis) |
PF00724(Oxidored_FMN) | 4 | GLU A 55ILE A 95ALA A 311ILE A 8 | None | 0.73A | 2xkwA-4a3uA:undetectable | 2xkwA-4a3uA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ab4 | XENOBIOTIC REDUCTASEB (Pseudomonasputida) |
PF00724(Oxidored_FMN) | 4 | GLU A 55ILE A 95ALA A 304ILE A 8 | None | 0.81A | 2xkwA-4ab4A:undetectable | 2xkwA-4ab4A:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4au2 | SERPIN PEPTIDASEINHIBITOR, CLADE H(HEAT SHOCK PROTEIN47), MEMBER 1,(COLLAGEN BINDINGPROTEIN 1) (Canis lupus) |
PF00079(Serpin) | 4 | LEU A 306ILE A 269ARG A 405ALA A 59 | None | 0.74A | 2xkwA-4au2A:undetectable | 2xkwA-4au2A:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4buj | ANTIVIRAL HELICASESKI2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT) | 4 | LEU A 434ILE A 376ALA A 383ILE A 381 | None | 0.86A | 2xkwA-4bujA:undetectable | 2xkwA-4bujA:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ev1 | ANABENA TIC22 (Anabaena sp.) |
PF04278(Tic22) | 4 | LEU A 48ILE A 118GLN A 124ARG A 131 | None | 0.74A | 2xkwA-4ev1A:undetectable | 2xkwA-4ev1A:24.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3n | UNCHARACTERIZED ACR,COG1565 SUPERFAMILY (Burkholderiathailandensis) |
PF02636(Methyltransf_28) | 4 | LEU A 43ILE A 54ARG A 213ALA A 204 | None | 0.83A | 2xkwA-4f3nA:undetectable | 2xkwA-4f3nA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7a | CRISPR-ASSOCIATEDPROTEIN CSE2 (Thermusthermophilus) |
PF09485(CRISPR_Cse2) | 4 | GLU A 88ILE A 126ALA A 106ILE A 111 | None | 0.84A | 2xkwA-4h7aA:undetectable | 2xkwA-4h7aA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hne | PHOSPHATIDYLINOSITOL4-KINASE TYPE2-ALPHA (Homo sapiens) |
PF00454(PI3_PI4_kinase) | 4 | LEU A 282GLU A 280ILE A 340ILE A 345 | LEU A 282 ( 0.6A)GLU A 280 ( 0.6A)ILE A 340 ( 0.6A)ILE A 345 (-0.5A) | 0.85A | 2xkwA-4hneA:undetectable | 2xkwA-4hneA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htt | SEC-INDEPENDENTPROTEIN TRANSLOCASEPROTEIN TATC,LYSOZYME (Aquifexaeolicus;Escherichiavirus T4) |
PF00902(TatC) | 4 | LEU A 52ILE A 150ALA A 115ILE A 74 | None | 0.69A | 2xkwA-4httA:undetectable | 2xkwA-4httA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ijm | CIRCADIAN CLOCKPROTEIN KINASE KAIC (Synechococcuselongatus) |
PF06745(ATPase) | 4 | LEU A 325GLU A 336ILE A 346ILE A 408 | None | 0.79A | 2xkwA-4ijmA:undetectable | 2xkwA-4ijmA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iyp | IMMUNOGLOBULIN-BINDING PROTEIN 1SERINE/THREONINE-PROTEIN PHOSPHATASE 2ACATALYTIC SUBUNITALPHA ISOFORM (Homo sapiens) |
PF00149(Metallophos)PF04177(TAP42) | 4 | LEU A 113ILE A 208GLN A 213ALA C 140 | None | 0.84A | 2xkwA-4iypA:undetectable | 2xkwA-4iypA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0h | CONSERVEDHYPOTHETICALPROTEIN, PUTATIVEANTI-SIGMA FACTOR (Parabacteroidesdistasonis) |
PF04773(FecR)PF16344(DUF4974) | 4 | LEU A 289ILE A 272ALA A 213ILE A 239 | None | 0.85A | 2xkwA-4m0hA:undetectable | 2xkwA-4m0hA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2f | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Pseudarthrobacterchlorophenolicus) |
PF01547(SBP_bac_1) | 4 | LEU A 411ILE A 227ALA A 271ILE A 267 | None | 0.81A | 2xkwA-4r2fA:undetectable | 2xkwA-4r2fA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6l | BACTERIOPHYTOCHROME(LIGHT-REGULATEDSIGNAL TRANSDUCTIONHISTIDINE KINASE),PHYB1 (Rhodopseudomonaspalustris) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | LEU A 426ILE A 498GLN A 330ALA A 353 | None | 0.84A | 2xkwA-4r6lA:undetectable | 2xkwA-4r6lA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ufc | GH95 (Bacteroidesovatus) |
PF14498(Glyco_hyd_65N_2) | 4 | LEU A 116GLN A 223ALA A 245ILE A 239 | None | 0.69A | 2xkwA-4ufcA:undetectable | 2xkwA-4ufcA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v33 | POLYSACCHARIDEDEACETYLASE-LIKEPROTEIN (Bacillusanthracis) |
PF01522(Polysacc_deac_1) | 4 | GLU A 111GLN A 118ALA A 121ILE A 49 | None | 0.84A | 2xkwA-4v33A:undetectable | 2xkwA-4v33A:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x04 | SOLUTE BINDINGPROTEIN (Citrobacterkoseri) |
PF03480(DctP) | 4 | GLU A 240GLN A 76ALA A 85ILE A 83 | BDP A 401 (-2.9A) MG A 404 ( 4.4A)NoneNone | 0.85A | 2xkwA-4x04A:undetectable | 2xkwA-4x04A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y2w | ALANINE RACEMASE 1 (Caldanaerobactersubterraneus) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | LEU A 74ILE A 39ALA A 207ILE A 212 | None | 0.75A | 2xkwA-4y2wA:undetectable | 2xkwA-4y2wA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg8 | ENDOGLUCANASE (Perinereisbrevicirris) |
PF00759(Glyco_hydro_9) | 4 | LEU A 105ILE A 80ALA A 259ILE A 315 | None | 0.83A | 2xkwA-4zg8A:undetectable | 2xkwA-4zg8A:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpx | ATP-DEPENDENTPROTEASE LON (Thermococcusonnurineus) |
PF01078(Mg_chelatase)PF13654(AAA_32) | 4 | LEU A 207ILE A 244ALA A 56ILE A 53 | None | 0.82A | 2xkwA-4zpxA:undetectable | 2xkwA-4zpxA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5avo | HOMOSERINEDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 4 | GLU A 264ILE A 278ALA A 239ILE A 209 | None | 0.70A | 2xkwA-5avoA:undetectable | 2xkwA-5avoA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5u | L-ASPARAGINASE (Pyrococcusfuriosus) |
PF00710(Asparaginase) | 4 | GLU A 116ILE A 33ALA A 127ILE A 78 | None | 0.71A | 2xkwA-5b5uA:undetectable | 2xkwA-5b5uA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfa | BETA-GALACTOSIDASE (Geobacillusstearothermophilus) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | LEU A 663GLU A 684ILE A 405ALA A 412 | None | 0.62A | 2xkwA-5dfaA:undetectable | 2xkwA-5dfaA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doz | JAMJ (Lyngbyamajuscula) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 5 | LEU A 124GLU A 128ILE A 132ALA A 160ILE A 157 | None | 1.44A | 2xkwA-5dozA:undetectable | 2xkwA-5dozA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doz | JAMJ (Lyngbyamajuscula) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 4 | LEU A 191ILE A 327ALA A 130ILE A 127 | None | 0.85A | 2xkwA-5dozA:undetectable | 2xkwA-5dozA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9a | BETA-GALACTOSIDASE (Rahnella sp. R3) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | LEU A 441ILE A 464ALA A 563ILE A 519 | None | 0.69A | 2xkwA-5e9aA:undetectable | 2xkwA-5e9aA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5emi | CELL WALLHYDROLASE/AUTOLYSIN (Nostocpunctiforme) |
PF01520(Amidase_3) | 4 | LEU A 460GLN A 599ALA A 605ILE A 476 | None | 0.79A | 2xkwA-5emiA:undetectable | 2xkwA-5emiA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f0o | COHESIN SUBUNITPDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P (Lachanceathermotolerans) |
no annotation | 4 | LEU A 526GLU A 695GLN A 717ILE A 749 | None | 0.84A | 2xkwA-5f0oA:undetectable | 2xkwA-5f0oA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fn4 | NICASTRIN (Homo sapiens) |
PF05450(Nicastrin) | 4 | LEU A 637GLU A 636GLN A 355ILE A 436 | None | 0.82A | 2xkwA-5fn4A:undetectable | 2xkwA-5fn4A:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l7l | ELP3 FAMILY, ELP3FAMILY (Dehalococcoidesmccartyi) |
PF04055(Radical_SAM)PF16199(Radical_SAM_C) | 4 | LEU A 401GLU A 405ILE A 419ARG A 364 | None | 0.85A | 2xkwA-5l7lA:undetectable | 2xkwA-5l7lA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m2n | ELONGATOR COMPLEXPROTEIN 2 (Saccharomycescerevisiae) |
PF00400(WD40) | 4 | GLU A 3ILE A 742GLN A 744ILE A 755 | None | 0.75A | 2xkwA-5m2nA:undetectable | 2xkwA-5m2nA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5me3 | SISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 4 | LEU A 958GLU A 994ILE A 983ALA A1020 | None | 0.85A | 2xkwA-5me3A:undetectable | 2xkwA-5me3A:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mfa | MYELOPEROXIDASE (Homo sapiens) |
PF03098(An_peroxidase) | 4 | LEU A 738ILE A 449ALA A 350ILE A 176 | None | 0.78A | 2xkwA-5mfaA:undetectable | 2xkwA-5mfaA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqc | VP2 (Black queencell virus) |
PF00073(Rhv) | 4 | ILE B 211GLN B 65ALA B 112ILE B 88 | None | 0.74A | 2xkwA-5mqcB:undetectable | 2xkwA-5mqcB:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ELECTRON TRANSFERFLAVOPROTEIN SMALLSUBUNIT (Clostridioidesdifficile) |
no annotation | 4 | LEU B 140ILE B 118ALA B 74ILE B 39 | None | 0.80A | 2xkwA-5ol2B:undetectable | 2xkwA-5ol2B:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ayv | FRUCTOSE-1,6-BISPHOSPHATASE CLASS 2 (Mycobacteriumtuberculosis) |
no annotation | 4 | GLU A 252ILE A 223ALA A 264ILE A 95 | None | 0.67A | 2xkwA-6ayvA:undetectable | 2xkwA-6ayvA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6azp | MYELOPEROXIDASE (Homo sapiens) |
no annotation | 4 | LEU A 738GLU A 429ILE A 449ILE A 176 | None | 0.78A | 2xkwA-6azpA:undetectable | 2xkwA-6azpA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6azp | MYELOPEROXIDASE (Homo sapiens) |
no annotation | 4 | LEU A 738ILE A 449ALA A 350ILE A 176 | None | 0.71A | 2xkwA-6azpA:undetectable | 2xkwA-6azpA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ch3 | FLAGELLAR SECRETIONCHAPERONEFLIS,FLAGELLIN (Salmonellaenterica) |
no annotation | 4 | LEU B 96ILE B 65ALA B 121ILE B 174 | None | 0.81A | 2xkwA-6ch3B:undetectable | 2xkwA-6ch3B:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbr | - (-) |
no annotation | 4 | LEU B 200ILE B 234ALA B 263ILE B 273 | None | 0.75A | 2xkwA-6dbrB:undetectable | 2xkwA-6dbrB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e29 | - (-) |
no annotation | 4 | ILE D 242ARG D 239ALA D 213ILE D 217 | None | 0.80A | 2xkwA-6e29D:undetectable | 2xkwA-6e29D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhw | GLUCOAMYLASE P (Amorphothecaresinae) |
no annotation | 4 | LEU A 47ILE A 91ALA A 496ILE A 187 | None | 0.73A | 2xkwA-6fhwA:undetectable | 2xkwA-6fhwA:14.23 |