SIMILAR PATTERNS OF AMINO ACIDS FOR 2XH9_B_J01B1437

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awb MYO-INOSITOL
MONOPHOSPHATASE

(Homo sapiens) 		PF00459
(Inositol_P) 		5 SER A 108
TYR A 211
ALA A 224
GLY A 223
ALA A 222
 None
 1.44A 2xh9B-1awbA:
1.8		 2xh9B-1awbA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE

(Salmonella
enterica) 		PF01739
(CheR)
PF03705
(CheR_N) 		5 THR A  94
TYR A 168
ALA A 163
ALA A 124
PHE A 208
 SAH  A 287 (-3.8A)
None
None
None
None
 1.39A 2xh9B-1bc5A:
undetectable		 2xh9B-1bc5A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fft UBIQUINOL OXIDASE

(Escherichia
coli) 		PF00115
(COX1) 		5 SER A 500
ALA A 467
GLY A 501
ALA A 502
PHE A 468
 None
None
None
HEM  A1001 ( 4.7A)
HEM  A1001 (-4.7A)
 1.42A 2xh9B-1fftA:
0.3		 2xh9B-1fftA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pe9 PECTATE LYASE A

(Dickeya
chrysanthemi) 		PF00544
(Pec_lyase_C) 		5 THR A  89
TYR A  36
ALA A  50
GLY A  51
ALA A  52
 None
 1.19A 2xh9B-1pe9A:
undetectable		 2xh9B-1pe9A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qaf PROTEIN (COPPER
AMINE OXIDASE)

(Escherichia
coli) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3)
PF07833
(Cu_amine_oxidN1) 		5 THR A 687
ALA A 484
GLY A 485
ALA A 486
PHE A 470
 None
 0.61A 2xh9B-1qafA:
3.7		 2xh9B-1qafA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxp MU-LIKE CALPAIN

(Bos taurus;
Rattus
norvegicus) 		PF00648
(Peptidase_C2)
PF01067
(Calpain_III)
PF13833
(EF-hand_8) 		5 SER A 778
TYR A 791
ALA A   2
GLY A   3
ALA A   5
 None
 1.39A 2xh9B-1qxpA:
0.0		 2xh9B-1qxpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sez PROTOPORPHYRINOGEN
OXIDASE,
MITOCHONDRIAL

(Nicotiana
tabacum) 		PF01593
(Amino_oxidase) 		5 SER A 481
THR A 303
ALA A 485
GLY A 482
ALA A  28
 None
 1.37A 2xh9B-1sezA:
0.0		 2xh9B-1sezA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 LYS A 432
SER A 193
TYR A 452
ALA A 191
GLY A 189
 None
 1.18A 2xh9B-1tf0A:
0.0		 2xh9B-1tf0A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1o NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Thermus
thermophilus) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		5 SER A 246
THR A 138
SER A 266
TYR A 124
GLY A 247
 None
 1.22A 2xh9B-1x1oA:
0.0		 2xh9B-1x1oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9y CYSTEINE PROTEINASE

(Staphylococcus
aureus) 		PF05543
(Peptidase_C47)
PF14731
(Staphopain_pro) 		5 THR A  79
ALA A  65
GLY A  66
ALA A  68
PHE A  64
 None
 1.42A 2xh9B-1x9yA:
2.2		 2xh9B-1x9yA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zxx 6-PHOSPHOFRUCTOKINAS
E

(Lactobacillus
delbrueckii) 		PF00365
(PFK) 		5 SER A 105
SER A   9
GLY A 108
ALA A 109
PHE A  76
 None
 1.41A 2xh9B-1zxxA:
undetectable		 2xh9B-1zxxA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ch6 N-ACETYL-D-GLUCOSAMI
NE KINASE

(Homo sapiens) 		PF01869
(BcrAD_BadFG) 		5 SER A 111
ALA A 113
GLY A 110
ALA A 109
ARG A 321
 None
 1.42A 2xh9B-2ch6A:
undetectable		 2xh9B-2ch6A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ch6 N-ACETYL-D-GLUCOSAMI
NE KINASE

(Homo sapiens) 		PF01869
(BcrAD_BadFG) 		5 SER A 111
TYR A 331
ALA A 113
GLY A 110
ALA A 109
 None
 1.46A 2xh9B-2ch6A:
undetectable		 2xh9B-2ch6A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4w GLYCEROL KINASE

(Cellulomonas
sp.) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		5 THR A 186
SER A 222
TYR A 226
ALA A 448
ALA A 249
 None
 1.47A 2xh9B-2d4wA:
0.5		 2xh9B-2d4wA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef4 ARGINASE

(Thermus
thermophilus) 		PF00491
(Arginase) 		5 SER A 103
ALA A 107
GLY A 106
ALA A 105
ARG A 111
 None
 1.28A 2xh9B-2ef4A:
undetectable		 2xh9B-2ef4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6k METAL-DEPENDENT
HYDROLASE

(Lactobacillus
plantarum) 		PF04909
(Amidohydro_2) 		5 SER A 265
THR A 270
SER A 275
GLY A 264
ALA A 241
 None
 1.46A 2xh9B-2f6kA:
undetectable		 2xh9B-2f6kA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR

(Agrobacterium
fabrum) 		PF00126
(HTH_1) 		5 SER A  40
SER A  38
ALA A  42
GLY A  43
ALA A  53
 None
 1.36A 2xh9B-2ijlA:
undetectable		 2xh9B-2ijlA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE

(Cupriavidus
pinatubonensis) 		PF05013
(FGase) 		5 SER A  32
SER A  29
ALA A  74
GLY A  33
PHE A  76
 None
 1.49A 2xh9B-2q7sA:
undetectable		 2xh9B-2q7sA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4d PHOSPHOLYSINE
PHOSPHOHISTIDINE
INORGANIC
PYROPHOSPHATE
PHOSPHATASE

(Homo sapiens) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		5 SER A  36
THR A 235
ALA A  34
GLY A  35
ALA A 258
 None
 1.30A 2xh9B-2x4dA:
undetectable		 2xh9B-2x4dA:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xfs ORF12

(Streptomyces
clavuligerus) 		PF13354
(Beta-lactamase2) 		8 LYS A  89
THR A 209
SER A 234
TYR A 359
ALA A 376
GLY A 377
PHE A 385
ARG A 418
 J01  A 600 (-2.8A)
J01  A 600 (-3.2A)
J01  A 600 (-3.4A)
J01  A 600 (-4.8A)
J01  A 600 (-3.5A)
J01  A 600 ( 3.8A)
J01  A 600 (-4.7A)
J01  A 600 ( 2.8A)
 0.15A 2xh9B-2xfsA:
65.6		 2xh9B-2xfsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xfs ORF12

(Streptomyces
clavuligerus) 		PF13354
(Beta-lactamase2) 		5 SER A 378
THR A 209
ALA A 173
GLY A 377
ALA A 376
 J01  A 600 (-3.4A)
J01  A 600 (-3.2A)
J01  A 600 ( 4.0A)
J01  A 600 ( 3.8A)
J01  A 600 (-3.5A)
 1.20A 2xh9B-2xfsA:
65.6		 2xh9B-2xfsA:
99.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		5 SER A  49
SER A  52
ALA A 347
GLY A 346
ALA A 345
 None
 1.24A 2xh9B-2xn6A:
1.4		 2xh9B-2xn6A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9e MYOSIN-2

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		5 SER X 181
THR X 230
SER X 236
GLY X 182
PHE X 129
 None
 1.40A 2xh9B-2y9eX:
undetectable		 2xh9B-2y9eX:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		5 LYS A 209
SER A  74
TYR A  97
GLY A  71
ARG A 205
 None
 1.22A 2xh9B-2yv3A:
1.7		 2xh9B-2yv3A:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bit FACT COMPLEX SUBUNIT
SPT16

(Saccharomyces
cerevisiae) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		5 SER A 187
THR A 419
SER A 299
TYR A 257
GLY A 190
 None
 1.43A 2xh9B-3bitA:
undetectable		 2xh9B-3bitA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fed GLUTAMATE
CARBOXYPEPTIDASE III

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		5 SER A 509
TYR A 542
GLY A 508
PHE A 199
ARG A 200
 ZN  A1752 ( 4.9A)
BIX  A   1 (-4.7A)
BIX  A   1 (-3.4A)
BIX  A   1 ( 4.8A)
BIX  A   1 (-2.7A)
 1.23A 2xh9B-3fedA:
undetectable		 2xh9B-3fedA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpz THIAZOLE
BIOSYNTHETIC ENZYME

(Saccharomyces
cerevisiae) 		PF01946
(Thi4) 		5 SER A 312
THR A 234
ALA A 316
GLY A 313
ALA A  80
 None
 1.25A 2xh9B-3fpzA:
undetectable		 2xh9B-3fpzA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nks PROTOPORPHYRINOGEN
OXIDASE

(Homo sapiens) 		PF01593
(Amino_oxidase) 		5 SER A  13
SER A 462
ALA A  17
GLY A  14
ALA A 285
 FAD  A 479 (-3.0A)
None
None
None
None
 1.26A 2xh9B-3nksA:
undetectable		 2xh9B-3nksA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osu 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Staphylococcus
aureus) 		PF13561
(adh_short_C2) 		5 LYS A 166
SER A 140
ALA A 159
GLY A 144
ALA A 145
 None
 1.36A 2xh9B-3osuA:
undetectable		 2xh9B-3osuA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT

(uncultured
archaeon) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		5 THR A 304
TYR A 329
ALA A 508
GLY A 509
ALA A 512
 None
 1.23A 2xh9B-3sqgA:
undetectable		 2xh9B-3sqgA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8x TRANSFERRIN-BINDING
PROTEIN 1

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		5 SER A 159
THR A 623
SER A 625
GLY A 647
ARG A 701
 None
 1.41A 2xh9B-3v8xA:
1.5		 2xh9B-3v8xA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3s 6-PHOSPHOFRUCTOKINAS
E

(Bacillus
subtilis) 		PF00365
(PFK) 		5 SER A 105
SER A   9
GLY A 108
ALA A 109
PHE A  76
 None
 1.28A 2xh9B-4a3sA:
undetectable		 2xh9B-4a3sA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4as5 INOSITOL
MONOPHOSPHATASE 1

(Mus musculus) 		PF00459
(Inositol_P) 		5 SER A 108
TYR A 211
ALA A 224
GLY A 223
ALA A 222
 None
 1.44A 2xh9B-4as5A:
2.0		 2xh9B-4as5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fm9 DNA TOPOISOMERASE
2-ALPHA

(Homo sapiens) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		5 SER A 750
THR A 732
ALA A 752
GLY A 749
ALA A 748
 None
 1.32A 2xh9B-4fm9A:
undetectable		 2xh9B-4fm9A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h4c 4-HYDROXY-3-METHYLBU
T-2-ENYL DIPHOSPHATE
REDUCTASE

(Escherichia
coli) 		PF02401
(LYTB) 		5 SER A 228
SER A 225
ALA A 268
GLY A 267
ALA A 266
 10D  A 402 ( 4.8A)
10D  A 402 (-2.4A)
SF4  A 401 ( 4.0A)
None
None
 1.25A 2xh9B-4h4cA:
undetectable		 2xh9B-4h4cA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4i 6-PHOSPHOFRUCTOKINAS
E

(Geobacillus
stearothermophilus) 		PF00365
(PFK) 		5 SER A 105
SER A   9
GLY A 108
ALA A 109
PHE A  76
 None
 1.48A 2xh9B-4i4iA:
undetectable		 2xh9B-4i4iA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1r CELLULASE 5

(soil metagenome) 		PF00150
(Cellulase) 		5 SER A 284
SER A 223
ALA A 288
GLY A 285
ALA A 265
 None
 1.09A 2xh9B-4m1rA:
undetectable		 2xh9B-4m1rA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptz FMN REDUCTASE SSUE

(Escherichia
coli) 		no annotation 5 SER C   8
SER C  13
ALA C   6
ALA C  72
ARG C  23
 FMN  C 201 (-2.6A)
FMN  C 201 (-2.5A)
None
None
None
 1.19A 2xh9B-4ptzC:
undetectable		 2xh9B-4ptzC:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptz FMN REDUCTASE SSUE

(Escherichia
coli) 		no annotation 5 SER C   8
SER C  13
ALA C   6
GLY C   7
ALA C  72
 FMN  C 201 (-2.6A)
FMN  C 201 (-2.5A)
None
None
None
 1.39A 2xh9B-4ptzC:
undetectable		 2xh9B-4ptzC:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkz PUTATIVE
UNCHARACTERIZED
PROTEIN TA1305

(Thermoplasma
acidophilum) 		no annotation 5 SER A 108
SER A 139
ALA A 112
GLY A 111
ALA A 110
 ADP  A 401 (-3.2A)
None
None
ADP  A 401 (-3.3A)
None
 1.26A 2xh9B-4rkzA:
undetectable		 2xh9B-4rkzA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zc3 TERMINASE SMALL
SUBUNIT

(Bacillus phage
SF6) 		PF03592
(Terminase_2) 		5 SER A  39
ALA A  24
GLY A  42
ALA A  43
PHE A  13
 None
 1.50A 2xh9B-4zc3A:
undetectable		 2xh9B-4zc3A:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by7 3-OXOACYL-ACP
SYNTHASE III

(Verrucosispora
maris) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		5 SER A 105
THR A 183
SER A 315
ALA A 107
GLY A 106
 None
 1.26A 2xh9B-5by7A:
undetectable		 2xh9B-5by7A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eso 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE

(Mycobacterium
tuberculosis) 		PF02776
(TPP_enzyme_N) 		5 THR A 434
ALA A 417
GLY A  68
ALA A 414
ARG A  48
 None
 1.49A 2xh9B-5esoA:
undetectable		 2xh9B-5esoA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5njf METALLOPROTEASE PMBA
METALLOPROTEASE TLDD

(Escherichia
coli) 		PF01523
(PmbA_TldD) 		5 THR B 410
SER B 389
ALA A 425
GLY A 479
ALA A 245
 None
 1.35A 2xh9B-5njfB:
2.3		 2xh9B-5njfB:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xzu BETA-XYLANASE

(Bispora sp.
MEY-1) 		no annotation 5 SER A 145
TYR A 182
ALA A 196
GLY A 144
ALA A 143
 None
 1.36A 2xh9B-5xzuA:
undetectable		 2xh9B-5xzuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a8m -

(-) 		no annotation 5 SER A 188
THR A 420
SER A 300
TYR A 258
GLY A 191
 None
 1.32A 2xh9B-6a8mA:
undetectable		 2xh9B-6a8mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d5i PHOSPHOENOLPYRUVATE
CARBOXYKINASE (ATP)

(Escherichia
coli) 		no annotation 5 THR A 404
ALA A 412
GLY A 410
PHE A 413
ARG A  65
 None
None
None
None
PYR  A 602 (-4.0A)
 1.07A 2xh9B-6d5iA:
undetectable		 2xh9B-6d5iA:
10.51