SIMILAR PATTERNS OF AMINO ACIDS FOR 2XFH_A_CL6A1413

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brt BROMOPEROXIDASE A2

(Kitasatospora
aureofaciens) 		PF00561
(Abhydrolase_1) 		4 ALA A 198
ALA A 201
THR A 204
PHE A  76
 None
CL  A 278 (-3.7A)
None
None
 0.86A 2xfhA-1brtA:
0.0		 2xfhA-1brtA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)

(Cupriavidus
necator) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 GLN A 416
ALA A 227
ALA A 231
THR A 235
 None
 0.97A 2xfhA-1bxnA:
undetectable		 2xfhA-1bxnA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csj HEPATITIS C VIRUS
RNA POLYMERASE
(NS5B)

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 ALA A 393
ALA A 396
THR A 399
PHE A 429
 None
 0.93A 2xfhA-1csjA:
0.0		 2xfhA-1csjA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fgg GLUCURONYLTRANSFERAS
E I

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 HIS A 308
ALA A 254
ALA A 193
THR A  81
 UNX  A 338 ( 3.2A)
None
None
None
 0.93A 2xfhA-1fggA:
0.0		 2xfhA-1fggA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h79 ANAEROBIC
RIBONUCLEOTIDE-TRIPH
OSPHATE REDUCTASE
LARGE CHAIN

(Escherichia
virus T4) 		PF13597
(NRDD) 		4 ALA A 110
ALA A 113
THR A 116
PHE A 129
 TTP  A1586 ( 3.9A)
None
None
None
 1.01A 2xfhA-1h79A:
undetectable		 2xfhA-1h79A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Galdieria
partita) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 GLN A 414
ALA A 224
ALA A 228
THR A 232
 None
 1.08A 2xfhA-1iwaA:
0.0		 2xfhA-1iwaA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3n 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
SYNTHASE II

(Thermus
thermophilus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLN A  26
ALA A 345
ALA A 348
THR A 351
 None
 1.02A 2xfhA-1j3nA:
0.0		 2xfhA-1j3nA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llp LIGNIN PEROXIDASE

(Phanerochaete
chrysosporium) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		4 HIS A  30
GLN A  94
ALA A  36
ALA A  38
 None
 1.04A 2xfhA-1llpA:
0.0		 2xfhA-1llpA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mb9 BETA-LACTAM
SYNTHETASE

(Streptomyces
clavuligerus) 		PF00733
(Asn_synthase)
PF13537
(GATase_7) 		4 HIS A 463
ALA A 505
ALA A 473
PHE A 456
 None
 0.95A 2xfhA-1mb9A:
0.0		 2xfhA-1mb9A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT

(Mycobacterium
tuberculosis) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 HIS A 263
ALA A 700
ALA A 704
THR A 707
 None
 1.00A 2xfhA-1nl3A:
undetectable		 2xfhA-1nl3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		4 ALA A 193
ALA A 132
THR A 109
PHE A 113
 None
 1.05A 2xfhA-1q5aA:
undetectable		 2xfhA-1q5aA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r9j TRANSKETOLASE

(Leishmania
mexicana) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ALA A  34
ALA A  38
THR A  42
PHE A 295
 None
 0.75A 2xfhA-1r9jA:
undetectable		 2xfhA-1r9jA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s7j PHENAZINE
BIOSYNTHESIS PROTEIN
PHZF FAMILY

(Enterococcus
faecalis) 		PF02567
(PhzC-PhzF) 		4 ALA A 208
ALA A 206
THR A 190
PHE A 192
 None
 1.06A 2xfhA-1s7jA:
undetectable		 2xfhA-1s7jA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sng COG4826: SERINE
PROTEASE INHIBITOR

(Thermobifida
fusca) 		PF00079
(Serpin) 		4 HIS A  12
ALA A 237
THR A 241
PHE A   7
 None
 1.04A 2xfhA-1sngA:
undetectable		 2xfhA-1sngA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 HIS A 311
ALA A 256
ALA A 194
THR A  90
 UDP  A 503 (-4.2A)
None
None
None
 0.93A 2xfhA-1v84A:
undetectable		 2xfhA-1v84A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vb3 THREONINE SYNTHASE

(Escherichia
coli) 		PF00291
(PALP)
PF14821
(Thr_synth_N) 		4 HIS A 284
GLN A 364
ALA A 330
THR A 273
 None
 1.08A 2xfhA-1vb3A:
undetectable		 2xfhA-1vb3A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w61 B-CELL MITOGEN

(Trypanosoma
cruzi) 		PF05544
(Pro_racemase) 		4 ALA A 136
ALA A 140
THR A 144
PHE A 374
 None
 0.67A 2xfhA-1w61A:
undetectable		 2xfhA-1w61A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7i SALICYLIC
ACID-BINDING PROTEIN
2

(Nicotiana
tabacum) 		PF12697
(Abhydrolase_6) 		5 HIS A  80
GLN A 162
ALA A 240
ALA A 236
THR A 208
 None
 1.49A 2xfhA-1y7iA:
undetectable		 2xfhA-1y7iA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ys2 LIPASE

(Burkholderia
cepacia) 		PF00561
(Abhydrolase_1) 		4 GLN X 124
ALA X 160
ALA X 163
THR X 166
 None
 1.08A 2xfhA-1ys2X:
undetectable		 2xfhA-1ys2X:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlp PETAL DEATH PROTEIN

(Dianthus
caryophyllus) 		PF13714
(PEP_mutase) 		4 GLN A  47
ALA A 267
ALA A 263
THR A 259
 None
 1.01A 2xfhA-1zlpA:
undetectable		 2xfhA-1zlpA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7u ATP SYNTHASE DELTA
CHAIN

(Escherichia
coli) 		PF00213
(OSCP) 		4 ALA B  32
ALA B  35
THR B  38
PHE B  60
 None
 0.97A 2xfhA-2a7uB:
undetectable		 2xfhA-2a7uB:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2i AMMONIUM TRANSPORTER

(Archaeoglobus
fulgidus) 		PF00909
(Ammonium_transp) 		4 ALA A  98
ALA A 102
THR A 105
PHE A 117
 None
 0.77A 2xfhA-2b2iA:
undetectable		 2xfhA-2b2iA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dby GTP-BINDING PROTEIN

(Thermus
thermophilus) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		4 HIS A  84
GLN A 175
ALA A 138
ALA A 141
 None
 1.08A 2xfhA-2dbyA:
undetectable		 2xfhA-2dbyA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dou PROBABLE
N-SUCCINYLDIAMINOPIM
ELATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 HIS A 196
ALA A 175
ALA A 173
THR A 171
 None
 1.06A 2xfhA-2douA:
undetectable		 2xfhA-2douA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dup VESICULAR
INTEGRAL-MEMBRANE
PROTEIN VIP36

(Canis lupus) 		PF03388
(Lectin_leg-like) 		4 GLN A  78
ALA A 134
ALA A 257
THR A  91
 None
 1.07A 2xfhA-2dupA:
undetectable		 2xfhA-2dupA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef0 ORNITHINE
CARBAMOYLTRANSFERASE

(Thermus
thermophilus) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 HIS A 275
GLN A 284
THR A 219
PHE A 257
 None
 0.97A 2xfhA-2ef0A:
undetectable		 2xfhA-2ef0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eh6 ACETYLORNITHINE
AMINOTRANSFERASE

(Aquifex
aeolicus) 		PF00202
(Aminotran_3) 		4 HIS A 128
ALA A 238
ALA A 102
PHE A 120
 None
 1.09A 2xfhA-2eh6A:
undetectable		 2xfhA-2eh6A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fr5 CYTIDINE DEAMINASE

(Mus musculus) 		PF00383
(dCMP_cyt_deam_1) 		4 HIS A  14
ALA A  84
ALA A  86
THR A 118
 None
 1.07A 2xfhA-2fr5A:
undetectable		 2xfhA-2fr5A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		4 HIS A 551
GLN A 510
ALA A 265
THR A 268
 None
 1.03A 2xfhA-2gq3A:
undetectable		 2xfhA-2gq3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2grj DEPHOSPHO-COA KINASE

(Thermotoga
maritima) 		PF01121
(CoaE) 		4 HIS A  84
GLN A 145
ALA A 106
THR A   6
 COD  A 201 (-3.7A)
COD  A 201 (-3.5A)
COD  A 201 ( 3.8A)
None
 1.04A 2xfhA-2grjA:
undetectable		 2xfhA-2grjA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0r NICOTINAMIDASE

(Saccharomyces
cerevisiae) 		PF00857
(Isochorismatase) 		4 HIS A 135
ALA A 170
ALA A 172
THR A 182
 None
 0.99A 2xfhA-2h0rA:
undetectable		 2xfhA-2h0rA:
19.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2jjp CYTOCHROME P450
113A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		5 HIS A  88
ALA A 237
ALA A 241
THR A 245
PHE A 288
 KLN  A 413 ( 3.6A)
KLN  A 413 (-3.2A)
HEM  A 412 ( 3.4A)
HEM  A 412 (-3.4A)
KLN  A 413 (-3.7A)
 0.50A 2xfhA-2jjpA:
56.2		 2xfhA-2jjpA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nqo GAMMA-GLUTAMYLTRANSP
EPTIDASE

(Helicobacter
pylori) 		PF01019
(G_glu_transpept) 		4 HIS A  44
GLN A 213
ALA A  71
ALA A  73
 None
 1.07A 2xfhA-2nqoA:
undetectable		 2xfhA-2nqoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pth PEPTIDYL-TRNA
HYDROLASE

(Escherichia
coli) 		PF01195
(Pept_tRNA_hydro) 		4 ALA A 164
ALA A 168
THR A 172
PHE A 104
 None
 0.86A 2xfhA-2pthA:
undetectable		 2xfhA-2pthA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1f CHONDROITINASE

(Bacteroides
thetaiotaomicron) 		PF02278
(Lyase_8)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 GLN A 174
ALA A 268
ALA A 271
THR A 167
 None
 1.03A 2xfhA-2q1fA:
undetectable		 2xfhA-2q1fA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE

(Azospirillum
brasilense) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ALA A 362
ALA A 360
THR A 386
PHE A 454
 None
 1.03A 2xfhA-2q5oA:
undetectable		 2xfhA-2q5oA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qty POLY(ADP-RIBOSE)
GLYCOHYDROLASE ARH3

(Mus musculus) 		PF03747
(ADP_ribosyl_GH) 		4 ALA A 158
ALA A 162
THR A 165
PHE A  88
 None
 1.09A 2xfhA-2qtyA:
undetectable		 2xfhA-2qtyA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyh ALPHA-MANNOSIDASE

(Streptococcus
pyogenes) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 ALA A 391
ALA A 389
THR A 809
PHE A 407
 None
 1.09A 2xfhA-2wyhA:
undetectable		 2xfhA-2wyhA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xro HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGV

(Pseudomonas
putida) 		PF01614
(IclR)
PF09339
(HTH_IclR) 		4 GLN A 184
ALA A 142
ALA A 144
THR A 175
 None
 0.99A 2xfhA-2xroA:
undetectable		 2xfhA-2xroA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xym RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 ALA A 393
ALA A 396
THR A 399
PHE A 429
 None
 0.88A 2xfhA-2xymA:
undetectable		 2xfhA-2xymA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yky BETA-TRANSAMINASE

(Mesorhizobium
sp. LUK) 		PF00202
(Aminotran_3) 		4 ALA A 148
ALA A 152
THR A 155
PHE A 301
 None
 1.01A 2xfhA-2ykyA:
undetectable		 2xfhA-2ykyA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aex THREONINE SYNTHASE

(Thermus
thermophilus) 		PF00291
(PALP) 		4 HIS A 159
ALA A  72
ALA A 151
THR A 145
 None
 0.84A 2xfhA-3aexA:
undetectable		 2xfhA-3aexA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dte IRRE PROTEIN

(Deinococcus
deserti) 		PF06114
(Peptidase_M78) 		4 HIS A 217
ALA A 249
ALA A 222
THR A 225
 None
 1.06A 2xfhA-3dteA:
undetectable		 2xfhA-3dteA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3god CAS1

(Pseudomonas
aeruginosa) 		PF01867
(Cas_Cas1) 		4 HIS A 254
ALA A 267
ALA A 237
THR A 241
 MN  A 325 (-3.3A)
None
None
None
 1.02A 2xfhA-3godA:
undetectable		 2xfhA-3godA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hum PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		PF00768
(Peptidase_S11)
PF09211
(DUF1958) 		4 HIS A 214
ALA A 168
ALA A 166
THR A 174
 None
 1.07A 2xfhA-3humA:
undetectable		 2xfhA-3humA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V BETA CHAIN

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		4 HIS B 914
ALA B 929
ALA B 949
THR B 953
 None
 0.74A 2xfhA-3k70B:
undetectable		 2xfhA-3k70B:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3krz NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE

(Thermoanaerobacter
pseudethanolicus) 		PF00724
(Oxidored_FMN) 		4 HIS A 103
GLN A  79
ALA A 144
ALA A 148
 None
 1.05A 2xfhA-3krzA:
undetectable		 2xfhA-3krzA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465

(Oleispira
antarctica) 		PF01979
(Amidohydro_1) 		4 GLN A 210
ALA A 378
ALA A 376
THR A 385
 None
 0.96A 2xfhA-3lnpA:
undetectable		 2xfhA-3lnpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ow8 WD REPEAT-CONTAINING
PROTEIN 61

(Homo sapiens) 		PF00400
(WD40) 		4 ALA A  86
ALA A 109
THR A 123
PHE A 133
 None
 1.05A 2xfhA-3ow8A:
undetectable		 2xfhA-3ow8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ow8 WD REPEAT-CONTAINING
PROTEIN 61

(Homo sapiens) 		PF00400
(WD40) 		4 HIS A  87
ALA A 109
THR A 123
PHE A 133
 None
 1.06A 2xfhA-3ow8A:
undetectable		 2xfhA-3ow8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pg5 UNCHARACTERIZED
PROTEIN

(Corynebacterium
diphtheriae) 		PF13614
(AAA_31) 		4 ALA A 147
ALA A 145
THR A   3
PHE A 159
 None
 1.06A 2xfhA-3pg5A:
undetectable		 2xfhA-3pg5A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppi 3-HYDROXYACYL-COA
DEHYDROGENASE TYPE-2

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 ALA A 231
ALA A 235
THR A 239
PHE A   6
 None
 0.54A 2xfhA-3ppiA:
undetectable		 2xfhA-3ppiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgh RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		4 ALA A 393
ALA A 396
THR A 399
PHE A 429
 None
 0.86A 2xfhA-3qghA:
undetectable		 2xfhA-3qghA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rcy MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Roseovarius sp.
TM1035) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ALA A 372
ALA A 374
THR A  11
PHE A 341
 None
 0.89A 2xfhA-3rcyA:
undetectable		 2xfhA-3rcyA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rzu STAM-BINDING PROTEIN

(Homo sapiens) 		PF01398
(JAB) 		4 GLN A 304
ALA A 273
THR A 336
PHE A 267
 None
 1.04A 2xfhA-3rzuA:
undetectable		 2xfhA-3rzuA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rzv STAM-BINDING PROTEIN

(Homo sapiens) 		PF01398
(JAB) 		4 GLN A 304
ALA A 273
THR A 336
PHE A 267
 None
 1.03A 2xfhA-3rzvA:
undetectable		 2xfhA-3rzvA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4w MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Sulfitobacter
sp. NAS-14.1) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ALA A 372
ALA A 374
THR A  11
PHE A 341
 None
 0.90A 2xfhA-3t4wA:
undetectable		 2xfhA-3t4wA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wjs NADH OXIDASE

(Gluconobacter
oxydans) 		PF00724
(Oxidored_FMN) 		4 HIS A 189
ALA A 120
ALA A 141
PHE A 182
 None
 1.08A 2xfhA-3wjsA:
undetectable		 2xfhA-3wjsA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a05 CELLOBIOHYDROLASE
FAMILY 6

(Chaetomium
thermophilum) 		PF01341
(Glyco_hydro_6) 		4 GLN A 467
ALA A 450
THR A 452
PHE A 461
 None
 1.04A 2xfhA-4a05A:
undetectable		 2xfhA-4a05A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cag POLYSACCHARIDE LYASE
FAMILY 11 PROTEIN

(Bacillus
licheniformis) 		PF01839
(FG-GAP) 		4 HIS A 374
ALA A 426
ALA A 435
PHE A 402
 None
 0.98A 2xfhA-4cagA:
undetectable		 2xfhA-4cagA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cby HISTONE DEACETYLASE
4

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		4 GLN A 959
ALA A 905
ALA A 909
THR A 913
 None
 0.49A 2xfhA-4cbyA:
undetectable		 2xfhA-4cbyA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0p COP9 SIGNALOSOME
COMPLEX SUBUNIT 4

(Homo sapiens) 		PF01399
(PCI) 		4 GLN A 289
ALA A 225
ALA A 229
THR A 233
 None
 0.86A 2xfhA-4d0pA:
undetectable		 2xfhA-4d0pA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ex4 MALATE SYNTHASE G

(Mycobacterium
leprae) 		PF01274
(Malate_synthase) 		4 HIS A 556
GLN A 515
ALA A 266
THR A 269
 None
 1.05A 2xfhA-4ex4A:
undetectable		 2xfhA-4ex4A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE

(Sinorhizobium
meliloti) 		PF02627
(CMD) 		4 HIS A 221
ALA A  61
ALA A  60
THR A  91
 None
 0.96A 2xfhA-4g9qA:
undetectable		 2xfhA-4g9qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjh PHOSPHOMANNOMUTASE

(Brucella
melitensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ALA A  62
ALA A  65
THR A  29
PHE A 115
 None
 1.02A 2xfhA-4hjhA:
undetectable		 2xfhA-4hjhA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpv S-ADENOSYLMETHIONINE
SYNTHASE

(Sulfolobus
solfataricus) 		PF01941
(AdoMet_Synthase) 		4 HIS A  59
ALA A  41
ALA A  38
THR A 286
 None
 0.95A 2xfhA-4hpvA:
undetectable		 2xfhA-4hpvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2w PROTEIN UNC-45

(Caenorhabditis
elegans) 		PF11701
(UNC45-central) 		4 ALA A 710
ALA A 712
THR A 755
PHE A 724
 None
 0.92A 2xfhA-4i2wA:
undetectable		 2xfhA-4i2wA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza A
virus;
Kitasatospora
aureofaciens) 		PF00561
(Abhydrolase_1)
PF00598
(Flu_M1) 		4 ALA A 198
ALA A 201
THR A 204
PHE A  76
 None
 0.84A 2xfhA-4iq4A:
undetectable		 2xfhA-4iq4A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF

(Pseudomonas
putida) 		PF00171
(Aldedh) 		4 ALA A 179
ALA A 182
THR A 185
PHE A 171
 None
 1.10A 2xfhA-4jz6A:
undetectable		 2xfhA-4jz6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2a HALOALKANE
DEHALOGENASE

(Bradyrhizobium
elkanii) 		PF00561
(Abhydrolase_1) 		4 ALA A 227
ALA A 229
THR A 257
PHE A 254
 None
 1.06A 2xfhA-4k2aA:
undetectable		 2xfhA-4k2aA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjd INTESTINAL-TYPE
ALKALINE PHOSPHATASE
1

(Rattus
norvegicus) 		PF00245
(Alk_phosphatase) 		4 HIS A 153
ALA A  93
ALA A  96
PHE A 309
 SEP  A  92 ( 4.9A)
SEP  A  92 ( 3.7A)
SEP  A  92 ( 3.3A)
None
 1.04A 2xfhA-4kjdA:
undetectable		 2xfhA-4kjdA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ntc GLIT

(Aspergillus
fumigatus) 		PF07992
(Pyr_redox_2) 		4 ALA A  72
ALA A  75
THR A  78
PHE A  86
 None
 1.04A 2xfhA-4ntcA:
undetectable		 2xfhA-4ntcA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ofw PROTEIN DJ-1 HOMOLOG
D

(Arabidopsis
thaliana) 		PF01965
(DJ-1_PfpI) 		4 HIS A 371
ALA A 367
ALA A 366
THR A 331
 None
 1.00A 2xfhA-4ofwA:
undetectable		 2xfhA-4ofwA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ou4 ALPHA/BETA HYDROLASE
FOLD-3 DOMAIN
PROTEIN

(Pseudomonas sp.
ECU1011) 		PF07859
(Abhydrolase_3) 		4 HIS A  85
ALA A 128
ALA A 132
THR A 136
 None
 0.93A 2xfhA-4ou4A:
undetectable		 2xfhA-4ou4A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0d TRYPSIN-RESISTANT
SURFACE T6 PROTEIN

(Streptococcus
pyogenes) 		PF16569
(GramPos_pilinBB) 		4 ALA A 408
ALA A 368
THR A 385
PHE A 354
 None
 0.90A 2xfhA-4p0dA:
undetectable		 2xfhA-4p0dA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmw DIS3-LIKE
EXONUCLEASE 2

(Mus musculus) 		PF00773
(RNB)
PF17216
(Rrp44_CSD1) 		4 GLN A 722
ALA A 714
ALA A 716
THR A 598
 None
 1.09A 2xfhA-4pmwA:
undetectable		 2xfhA-4pmwA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8y CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 HIS A  13
GLN A  57
ALA A  49
ALA A  51
 MN  A 903 (-3.4A)
None
None
None
 1.05A 2xfhA-4w8yA:
undetectable		 2xfhA-4w8yA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcj POLYSACCHARIDE
DEACETYLASE

(Ammonifex
degensii) 		PF01522
(Polysacc_deac_1) 		4 ALA A 199
ALA A 203
THR A 206
PHE A 240
 None
 1.06A 2xfhA-4wcjA:
undetectable		 2xfhA-4wcjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj7 MALCAVERNIN

(Homo sapiens) 		no annotation 4 HIS A 137
ALA A 158
ALA A 140
PHE A 217
 None
 0.96A 2xfhA-4wj7A:
undetectable		 2xfhA-4wj7A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysj CALMODULIN-LIKE
DOMAIN PROTEIN
KINASE

(Eimeria tenella) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 ALA A 320
ALA A 317
THR A 313
PHE A 310
 None
 1.04A 2xfhA-4ysjA:
undetectable		 2xfhA-4ysjA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxk SIALIDASE A

(Streptococcus
pneumoniae) 		PF02973
(Sialidase) 		4 GLN A 268
ALA A 275
ALA A 176
THR A 265
 None
 1.09A 2xfhA-4zxkA:
undetectable		 2xfhA-4zxkA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzp CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
purpureum) 		PF00840
(Glyco_hydro_7) 		4 GLN A 318
ALA A 221
ALA A 223
THR A 225
 None
 1.00A 2xfhA-4zzpA:
undetectable		 2xfhA-4zzpA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzq CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
discoideum) 		PF00840
(Glyco_hydro_7) 		4 GLN A 318
ALA A 221
ALA A 223
THR A 225
 None
 1.09A 2xfhA-4zzqA:
undetectable		 2xfhA-4zzqA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brr TISSUE-TYPE
PLASMINOGEN
ACTIVATOR

(Homo sapiens) 		PF00089
(Trypsin) 		4 GLN E  30
ALA E  55
ALA E 195
PHE E  40
 None
 0.92A 2xfhA-5brrE:
undetectable		 2xfhA-5brrE:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5but KTR SYSTEM POTASSIUM
UPTAKE PROTEIN B

(Bacillus
subtilis) 		PF02386
(TrkH) 		4 ALA I  32
ALA I  55
THR I  59
PHE I  24
 None
 0.95A 2xfhA-5butI:
undetectable		 2xfhA-5butI:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hvc TYPE I MODULAR
POLYKETIDE SYNTHASE

(Mycobacterium
ulcerans) 		PF00550
(PP-binding) 		4 ALA A2064
ALA A2068
THR A2071
PHE A2089
 None
 1.01A 2xfhA-5hvcA:
undetectable		 2xfhA-5hvcA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxs SODIUM,CALCIUM
EXCHANGER

(Methanocaldococcus
jannaschii) 		PF01699
(Na_Ca_ex) 		4 ALA A  43
ALA A  47
THR A  50
PHE A  23
 None
 0.92A 2xfhA-5hxsA:
undetectable		 2xfhA-5hxsA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kn7 LIPID A BIOSYNTHESIS
LAUROYL
ACYLTRANSFERASE

(Acinetobacter
baumannii) 		PF03279
(Lip_A_acyltrans) 		4 ALA B 131
ALA B 134
THR B 137
PHE B 106
 None
 0.98A 2xfhA-5kn7B:
undetectable		 2xfhA-5kn7B:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III

(Methanococcoides
burtonii) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 GLN A 435
ALA A 216
ALA A 220
THR A 224
 None
 1.01A 2xfhA-5macA:
undetectable		 2xfhA-5macA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Rhodobacter
sphaeroides) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 GLN A 415
ALA A 226
ALA A 230
THR A 234
 None
 1.06A 2xfhA-5nv3A:
undetectable		 2xfhA-5nv3A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oas MALATE SYNTHASE G

(Pseudomonas
aeruginosa) 		no annotation 4 HIS A 549
GLN A 508
ALA A 266
THR A 269
 None
 1.08A 2xfhA-5oasA:
undetectable		 2xfhA-5oasA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ty7 PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		no annotation 4 HIS A 214
ALA A 168
ALA A 166
THR A 174
 None
 1.05A 2xfhA-5ty7A:
undetectable		 2xfhA-5ty7A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens) 		no annotation 4 ALA A 371
ALA A 415
THR A 458
PHE A 148
 None
 0.82A 2xfhA-5vanA:
undetectable		 2xfhA-5vanA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w95 CONSERVED MEMBRANE
PROTEIN OF
UNCHARACTERISED
FUNCTION

(Mycobacterium
tuberculosis) 		no annotation 4 GLN A  76
ALA A 152
ALA A 155
THR A 158
 None
 1.00A 2xfhA-5w95A:
undetectable		 2xfhA-5w95A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 4 HIS A 397
ALA A 425
THR A 423
PHE A 413
 None
 0.98A 2xfhA-5wbgA:
28.9		 2xfhA-5wbgA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi9 -

(-) 		no annotation 4 ALA A 371
ALA A 415
THR A 458
PHE A 148
 None
 0.93A 2xfhA-5wi9A:
undetectable		 2xfhA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a91 -

(-) 		no annotation 4 ALA A1291
ALA A1295
THR A1298
PHE A1115
 None
 1.03A 2xfhA-6a91A:
undetectable		 2xfhA-6a91A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axe MALATE SYNTHASE G

(Mycobacterium
marinum) 		PF01274
(Malate_synthase) 		4 HIS A 555
GLN A 514
ALA A 265
THR A 268
 None
 1.04A 2xfhA-6axeA:
undetectable		 2xfhA-6axeA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4m YERSINOPINE
DEHYDROGENASE

(Yersinia pestis) 		no annotation 4 HIS C 220
ALA C  64
ALA C  62
THR C 188
 None
 1.10A 2xfhA-6c4mC:
undetectable		 2xfhA-6c4mC:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5o POLYMERASE ACIDIC
PROTEIN
RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT

(Influenza B
virus) 		no annotation 4 GLN A 582
ALA B  16
ALA B  17
THR B  20
 None
 1.01A 2xfhA-6f5oA:
undetectable		 2xfhA-6f5oA:
13.95