SIMILAR PATTERNS OF AMINO ACIDS FOR 2XF3_A_J01A500_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4x | PROTEIN(2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE) (Rhodococcusjostii) |
PF12697(Abhydrolase_6) | 5 | HIS A 263VAL A 238LEU A 150GLY A 38ALA A 41 | None | 1.07A | 2xf3A-1c4xA:0.0 | 2xf3A-1c4xA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1del | DEOXYNUCLEOSIDEMONOPHOSPHATE KINASE (Escherichiavirus T4) |
no annotation | 5 | VAL A 79ILE A 122LEU A 90LEU A 142GLY A 139 | NoneNoneNoneNoneDGP A 301 (-3.4A) | 1.10A | 2xf3A-1delA:0.0 | 2xf3A-1delA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gxt | HYDROGENASEMATURATION PROTEINHYPF (Escherichiacoli) |
PF00708(Acylphosphatase) | 5 | VAL A 46ILE A 13LEU A 35LEU A 61ALA A 30 | CL A1092 (-4.9A)NoneNoneNoneNone | 1.00A | 2xf3A-1gxtA:0.0 | 2xf3A-1gxtA:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 5 | VAL A 535LEU A 837LEU A 806GLY A 802ALA A 799 | None | 1.26A | 2xf3A-1h7wA:0.0 | 2xf3A-1h7wA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1im9 | KILLER CELLIMMUNOGLOBULIN-LIKERECEPTOR 2DL1 (Homo sapiens) |
PF00047(ig) | 5 | ILE D 102LEU D 97LEU D 17GLY D 15ALA D 12 | None | 1.17A | 2xf3A-1im9D:0.0 | 2xf3A-1im9D:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jeq | KU70 (Homo sapiens) |
PF02037(SAP)PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 5 | VAL A 522ILE A 465LEU A 469ARG A 517ALA A 513 | None | 1.23A | 2xf3A-1jeqA:0.3 | 2xf3A-1jeqA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k3s | SIGE (Salmonellaenterica) |
PF07824(Chaperone_III) | 5 | VAL A 31ILE A 24LEU A 4LEU A 12ALA A 94 | None | 1.02A | 2xf3A-1k3sA:0.0 | 2xf3A-1k3sA:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4q | GLUTATHIONEREDUCTASE (Homo sapiens) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 377LEU A 215LEU A 223GLY A 196ALA A 199 | None | 1.09A | 2xf3A-1k4qA:0.0 | 2xf3A-1k4qA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m6y | S-ADENOSYL-METHYLTRANSFERASE MRAW (Thermotogamaritima) |
PF01795(Methyltransf_5) | 5 | VAL A 80ILE A 54LEU A 29ALA A 229LYS A 228 | None | 1.13A | 2xf3A-1m6yA:0.0 | 2xf3A-1m6yA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhs | PLASMA MEMBRANEATPASE (Neurosporacrassa) |
PF00122(E1-E2_ATPase)PF00690(Cation_ATPase_N)PF00702(Hydrolase) | 5 | VAL A 692ILE A 696LEU A 117LEU A 297GLY A 294 | None | 1.22A | 2xf3A-1mhsA:undetectable | 2xf3A-1mhsA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mtp | SERINE PROTEINASEINHIBITOR (SERPIN),CHAIN ASERINE PROTEINASEINHIBITOR (SERPIN),CHAIN B (Thermobifidafusca) |
PF00079(Serpin)no annotation | 5 | ILE B 344LEU A 162LEU A 305GLY A 314ALA A 164 | None | 1.22A | 2xf3A-1mtpB:undetectable | 2xf3A-1mtpB:7.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ndl | NUCLEOSIDEDIPHOSPHATE KINASE (Drosophilamelanogaster) |
PF00334(NDK) | 5 | VAL A 12ILE A 118LEU A 92ARG A 89GLY A 88 | None | 1.19A | 2xf3A-1ndlA:undetectable | 2xf3A-1ndlA:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1og6 | HYPOTHETICALOXIDOREDUCTASE YDHF (Escherichiacoli) |
PF00248(Aldo_ket_red) | 5 | VAL A 49ILE A 80LEU A 117GLY A 65ALA A 63 | None | 1.08A | 2xf3A-1og6A:undetectable | 2xf3A-1og6A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r82 | GLYCOPROTEIN-FUCOSYLGALACTOSIDEALPHA-GALACTOSYLTRANSFERASE (Homo sapiens) |
PF03414(Glyco_transf_6) | 5 | VAL A 277LEU A 324LEU A 306GLY A 267ALA A 268 | NoneAOG A 452 ( 4.2A) HG A 402 ( 4.2A)NoneNone | 1.25A | 2xf3A-1r82A:undetectable | 2xf3A-1r82A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1svv | THREONINE ALDOLASE (Leishmaniamajor) |
PF01212(Beta_elim_lyase) | 5 | VAL A 69ILE A 226LEU A 260GLY A 213ALA A 214 | None | 1.24A | 2xf3A-1svvA:undetectable | 2xf3A-1svvA:24.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3q | QUINOLINE2-OXIDOREDUCTASELARGE SUBUNIT (Pseudomonasputida) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | VAL B 606ILE B 491LEU B 522ARG B 565GLY B 523 | None | 1.20A | 2xf3A-1t3qB:1.1 | 2xf3A-1t3qB:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t82 | HYPOTHETICALACETYLTRANSFERASE (Shewanellaoneidensis) |
PF09500(YiiD_C) | 5 | HIS A 13TRP A 12ILE A 16LEU A 61ALA A 38 | None | 1.20A | 2xf3A-1t82A:undetectable | 2xf3A-1t82A:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6g | TIP120 PROTEIN (Homo sapiens) |
PF08623(TIP120) | 5 | ILE C 932LEU C 970LEU C 958GLY C 956ALA C 988 | None | 1.22A | 2xf3A-1u6gC:undetectable | 2xf3A-1u6gC:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfg | GLUCOSAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] (Escherichiacoli) |
PF13522(GATase_6) | 5 | VAL A 96LEU A 196LEU A 16GLY A 19ALA A 195 | None | 1.25A | 2xf3A-1xfgA:undetectable | 2xf3A-1xfgA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8q | UBIQUITIN-LIKE 2ACTIVATING ENZYMEE1B (Homo sapiens) |
PF00899(ThiF)PF14732(UAE_UbL)PF16195(UBA2_C) | 5 | VAL B 20ILE B 44LEU B 33GLY B 29ALA B 115 | None | 1.17A | 2xf3A-1y8qB:undetectable | 2xf3A-1y8qB:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zgh | METHIONYL-TRNAFORMYLTRANSFERASE (Ruminiclostridiumthermocellum) |
PF00551(Formyl_trans_N) | 5 | VAL A 72ILE A 103LEU A 90LEU A 78GLY A 81 | None | 0.95A | 2xf3A-1zghA:undetectable | 2xf3A-1zghA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6y | EMP47P (FORM1) (Saccharomycescerevisiae) |
PF03388(Lectin_leg-like) | 5 | VAL A 180ILE A 164LEU A 115GLY A 129ALA A 149 | None | 0.89A | 2xf3A-2a6yA:undetectable | 2xf3A-2a6yA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a70 | EMP47P (Saccharomycescerevisiae) |
PF03388(Lectin_leg-like) | 5 | VAL A 180ILE A 164LEU A 115GLY A 129ALA A 149 | NoneNoneNoneNoneEDO A 4 ( 4.9A) | 0.96A | 2xf3A-2a70A:undetectable | 2xf3A-2a70A:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ILE A 898LEU A 812LEU A 712ALA A 719LYS A 720 | None | 1.27A | 2xf3A-2ax9A:undetectable | 2xf3A-2ax9A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2can | ORNITHINEAMINOTRANSFERASE (Homo sapiens) |
PF00202(Aminotran_3) | 5 | VAL A 238ILE A 232LEU A 418GLY A 273ALA A 349 | None | 1.12A | 2xf3A-2canA:undetectable | 2xf3A-2canA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e5v | L-ASPARTATE OXIDASE (Sulfurisphaeratokodaii) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | VAL A 16ILE A 134LEU A 27GLY A 6ALA A 171 | NoneNoneNoneFAD A1002 (-3.3A)None | 1.18A | 2xf3A-2e5vA:undetectable | 2xf3A-2e5vA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g0w | LMO2234 PROTEIN (Listeriamonocytogenes) |
PF01261(AP_endonuc_2) | 5 | HIS A 109VAL A 244LEU A 137GLY A 106ALA A 102 | None | 1.07A | 2xf3A-2g0wA:undetectable | 2xf3A-2g0wA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hls | PROTEIN DISULFIDEOXIDOREDUCTASE (Aeropyrumpernix) |
PF13192(Thioredoxin_3) | 5 | HIS A 161VAL A 114LEU A 176LEU A 93GLY A 95 | None | 1.04A | 2xf3A-2hlsA:undetectable | 2xf3A-2hlsA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jf7 | STRICTOSIDINE-O-BETA-D-GLUCOSIDASE (Rauvolfiaserpentina) |
PF00232(Glyco_hydro_1) | 5 | VAL A 486ILE A 93LEU A 111GLY A 52ALA A 51 | None | 1.22A | 2xf3A-2jf7A:undetectable | 2xf3A-2jf7A:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qa1 | POLYKETIDE OXYGENASEPGAE (Streptomycessp. PGA64) |
PF01494(FAD_binding_3) | 5 | VAL A 149LEU A 21ARG A 22GLY A 19ALA A 107 | None | 1.09A | 2xf3A-2qa1A:undetectable | 2xf3A-2qa1A:26.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qa2 | POLYKETIDE OXYGENASECABE (Streptomyces) |
PF01494(FAD_binding_3) | 5 | VAL A 149LEU A 21ARG A 22GLY A 19ALA A 107 | None | 1.11A | 2xf3A-2qa2A:undetectable | 2xf3A-2qa2A:25.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qna | IMPORTIN SUBUNITBETA-1 (Homo sapiens) |
PF13513(HEAT_EZ) | 5 | ILE A 797LEU A 869LEU A 825GLY A 823ALA A 865 | None | 1.21A | 2xf3A-2qnaA:undetectable | 2xf3A-2qnaA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgh | ALPHA-GLYCEROPHOSPHATE OXIDASE (Streptococcussp.) |
PF01266(DAO)PF16901(DAO_C) | 5 | VAL A 569ILE A 573LEU A 514LEU A 536GLY A 535 | None | 1.25A | 2xf3A-2rghA:undetectable | 2xf3A-2rghA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vo8 | EXO-ALPHA-SIALIDASE (Clostridiumperfringens) |
PF12135(Sialidase_penC) | 5 | VAL A 973ILE A1022LEU A1046LEU A1028GLY A 963 | None | 1.14A | 2xf3A-2vo8A:undetectable | 2xf3A-2vo8A:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 5 | VAL A 912ILE A1059LEU A 919LEU A1032GLY A 890 | None | 1.12A | 2xf3A-2vz9A:undetectable | 2xf3A-2vz9A:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x50 | TRYPANOTHIONEREDUCTASE (Leishmaniainfantum) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 372LEU A 219LEU A 227GLY A 197ALA A 200 | NoneNoneNoneNDP A1488 (-3.2A)None | 1.13A | 2xf3A-2x50A:undetectable | 2xf3A-2x50A:22.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xfs | ORF12 (Streptomycesclavuligerus) |
PF13354(Beta-lactamase2) | 10 | HIS A 84TRP A 91VAL A 93ILE A 103LEU A 362LEU A 415ARG A 418GLY A 419ALA A 422LYS A 423 | J01 A 500 (-3.5A)J01 A 500 (-4.6A)NoneNoneNoneNoneJ01 A 600 ( 2.8A)J01 A 500 (-3.4A)J01 A 500 (-3.4A)J01 A 500 (-3.7A) | 0.14A | 2xf3A-2xfsA:67.5 | 2xf3A-2xfsA:99.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euo | TYPE III PENTAKETIDESYNTHASE (Neurosporacrassa) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | VAL A 217ILE A 14LEU A 385GLY A 371ALA A 303 | None | 1.23A | 2xf3A-3euoA:undetectable | 2xf3A-3euoA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f1x | SERINEACETYLTRANSFERASE (Bacteroidesvulgatus) |
PF00132(Hexapep) | 5 | VAL A 174ILE A 87LEU A 123LEU A 83ALA A 49 | None | 1.28A | 2xf3A-3f1xA:0.5 | 2xf3A-3f1xA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8r | THIOREDOXINREDUCTASE (TRXB-3) (Sulfolobussolfataricus) |
PF07992(Pyr_redox_2) | 5 | VAL A 104ILE A 95LEU A 119GLY A 120ALA A 27 | None | 1.15A | 2xf3A-3f8rA:undetectable | 2xf3A-3f8rA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h8n | KILLER CELLIMMUNOGLOBULIN-LIKERECEPTOR 2DS4 (Homo sapiens) |
PF00047(ig) | 5 | ILE A 102LEU A 97LEU A 17GLY A 15ALA A 12 | None | 1.20A | 2xf3A-3h8nA:undetectable | 2xf3A-3h8nA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h9c | METHIONYL-TRNASYNTHETASE (Escherichiacoli) |
PF09334(tRNA-synt_1g) | 5 | HIS A 323VAL A 326ILE A 370LEU A 363ALA A 31 | None | 1.07A | 2xf3A-3h9cA:undetectable | 2xf3A-3h9cA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic1 | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Haemophilusinfluenzae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 88LEU A 12LEU A 93GLY A 103ALA A 106 | None | 1.24A | 2xf3A-3ic1A:undetectable | 2xf3A-3ic1A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipc | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (AMINO ACID) (Agrobacteriumfabrum) |
PF13458(Peripla_BP_6) | 5 | VAL A 3ILE A 44LEU A 305GLY A 288ALA A 289 | None | 1.15A | 2xf3A-3ipcA:undetectable | 2xf3A-3ipcA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | SMALL NUCLEARRIBONUCLEOPROTEIN SMD1SMALL NUCLEARRIBONUCLEOPROTEIN SMD2 (Schizosaccharomycespombe) |
PF01423(LSM) | 5 | VAL G 109ILE G 45LEU F 3LEU G 68ALA G 59 | None | 1.08A | 2xf3A-3jb9G:undetectable | 2xf3A-3jb9G:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kd8 | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Thermoplasmaacidophilum) |
PF01676(Metalloenzyme)PF10143(PhosphMutase) | 5 | VAL A 137ILE A 126LEU A 198GLY A 215ALA A 112 | None | 1.26A | 2xf3A-3kd8A:undetectable | 2xf3A-3kd8A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p3q | MMOQ (Methylococcuscapsulatus) |
PF08668(HDOD) | 5 | ILE A 141LEU A 220LEU A 138GLY A 157ALA A 160 | None | 1.20A | 2xf3A-3p3qA:undetectable | 2xf3A-3p3qA:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qan | 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE1 (Bacillushalodurans) |
PF00171(Aldedh) | 5 | VAL A 176ILE A 178LEU A 39GLY A 236ALA A 70 | None | 1.19A | 2xf3A-3qanA:undetectable | 2xf3A-3qanA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjl | 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (Bacilluslicheniformis) |
PF00171(Aldedh) | 5 | VAL A 177ILE A 179LEU A 40GLY A 237ALA A 71 | None | 1.23A | 2xf3A-3rjlA:undetectable | 2xf3A-3rjlA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rle | GOLGIREASSEMBLY-STACKINGPROTEIN 2 (Homo sapiens) |
PF04495(GRASP55_65) | 5 | TRP A 113VAL A 115ILE A 194LEU A 149ALA A 139 | None | 1.06A | 2xf3A-3rleA:undetectable | 2xf3A-3rleA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tcs | RACEMASE, PUTATIVE (Roseobacterdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | VAL A 272LEU A 63LEU A 262ARG A 267GLY A 264 | None | 1.02A | 2xf3A-3tcsA:undetectable | 2xf3A-3tcsA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thn | EXONUCLEASE,PUTATIVE (Thermotogamaritima) |
PF00149(Metallophos) | 5 | HIS A 16ILE A 236LEU A 60LEU A 34GLY A 18 | MN A 360 (-3.9A)NoneNoneNoneNone | 1.14A | 2xf3A-3thnA:undetectable | 2xf3A-3thnA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tho | EXONUCLEASE,PUTATIVE (Thermotogamaritima) |
PF00149(Metallophos) | 5 | HIS B 16ILE B 236LEU B 60LEU B 34GLY B 18 | MN B 1 (-3.9A)NoneNoneNoneNone | 1.17A | 2xf3A-3thoB:undetectable | 2xf3A-3thoB:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqr | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Coxiellaburnetii) |
PF00551(Formyl_trans_N) | 5 | VAL A 140ILE A 153LEU A 6LEU A 193ALA A 189 | None | 1.22A | 2xf3A-3tqrA:undetectable | 2xf3A-3tqrA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uk1 | TRANSKETOLASE (Burkholderiathailandensis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | VAL A 415ILE A 430LEU A 198GLY A 145ALA A 147 | None | 1.19A | 2xf3A-3uk1A:undetectable | 2xf3A-3uk1A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wc3 | ENDO-1,4-BETA-GLUCANASE (Eisenia fetida) |
PF00759(Glyco_hydro_9) | 5 | ILE A 116LEU A 29LEU A 92GLY A 442ALA A 445 | None | 1.16A | 2xf3A-3wc3A:undetectable | 2xf3A-3wc3A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wc3 | ENDO-1,4-BETA-GLUCANASE (Eisenia fetida) |
PF00759(Glyco_hydro_9) | 5 | VAL A 185LEU A 29LEU A 92GLY A 442ALA A 445 | None | 1.27A | 2xf3A-3wc3A:undetectable | 2xf3A-3wc3A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zvt | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Actinomadurasp. R39) |
PF02113(Peptidase_S13) | 5 | VAL A 110LEU A 154LEU A 122GLY A 246ALA A 245 | None | 1.20A | 2xf3A-3zvtA:0.0 | 2xf3A-3zvtA:24.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b43 | TRANSLATIONINITIATION FACTORIF-2 (Thermusthermophilus) |
PF00009(GTP_EFTU)PF04760(IF2_N) | 5 | VAL A 77ILE A 125LEU A 252GLY A 320ALA A 141 | None | 1.15A | 2xf3A-4b43A:undetectable | 2xf3A-4b43A:24.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bju | N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE (Aspergillusfumigatus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I) | 5 | ILE A 142LEU A 80LEU A 145GLY A 47ALA A 50 | None | 1.18A | 2xf3A-4bjuA:undetectable | 2xf3A-4bjuA:25.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d47 | LEVANSUCRASE (Erwiniaamylovora) |
PF02435(Glyco_hydro_68) | 5 | VAL A 179LEU A 69LEU A 146GLY A 133ALA A 132 | NoneNoneNoneNoneFRU A1415 ( 4.7A) | 1.26A | 2xf3A-4d47A:1.9 | 2xf3A-4d47A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dna | PROBABLE GLUTATHIONEREDUCTASE (Sinorhizobiummeliloti) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 351LEU A 198LEU A 206GLY A 179ALA A 182 | None | 1.08A | 2xf3A-4dnaA:undetectable | 2xf3A-4dnaA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4epa | PESTICIN RECEPTOR (Yersinia pestis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 5 | VAL A 547ILE A 528LEU A 110ARG A 112GLY A 113 | None | 1.26A | 2xf3A-4epaA:0.6 | 2xf3A-4epaA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1r | CATABOLITEREPRESSION CONTROLPROTEIN (Pseudomonasaeruginosa) |
PF03372(Exo_endo_phos) | 5 | VAL A 8LEU A 108ARG A 93GLY A 92ALA A 60 | None | 1.18A | 2xf3A-4f1rA:undetectable | 2xf3A-4f1rA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6f | PUTATIVE ALCOHOLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 325LEU A 181ARG A 207GLY A 208ALA A 209 | None | 1.22A | 2xf3A-4j6fA:undetectable | 2xf3A-4j6fA:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jg3 | CATABOLITEREPRESSION CONTROLPROTEIN (Pseudomonasaeruginosa) |
PF03372(Exo_endo_phos) | 5 | VAL A 11LEU A 111ARG A 96GLY A 95ALA A 63 | None | 1.15A | 2xf3A-4jg3A:undetectable | 2xf3A-4jg3A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jga | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Rickettsiarickettsii) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | VAL A 21ILE A 353LEU A 356GLY A 251ALA A 93 | None | 1.24A | 2xf3A-4jgaA:undetectable | 2xf3A-4jgaA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5r | OXYGENASE (Streptomycesargillaceus) |
PF01494(FAD_binding_3) | 5 | VAL A 163LEU A 31ARG A 32GLY A 29ALA A 121 | None | 1.12A | 2xf3A-4k5rA:undetectable | 2xf3A-4k5rA:26.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mrq | PHOSPHOMANNOMUTASE/PHOSPHOGLUCOMUTASE (Pseudomonasaeruginosa) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | VAL A 103ILE A 119LEU A 143LEU A 134ARG A 137 | None | 0.98A | 2xf3A-4mrqA:undetectable | 2xf3A-4mrqA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n3w | CREB-BINDING PROTEIN (Homo sapiens) |
PF00439(Bromodomain)PF06001(DUF902) | 5 | VAL A1157ILE A1138LEU A1196LEU A1142ALA A1093 | None | 1.20A | 2xf3A-4n3wA:undetectable | 2xf3A-4n3wA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n75 | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA (Escherichiacoli) |
PF01103(Bac_surface_Ag) | 5 | VAL A 660LEU A 501GLY A 707ALA A 705LYS A 671 | None | 1.24A | 2xf3A-4n75A:undetectable | 2xf3A-4n75A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ote | LIPOPROTEIN (Clostridioidesdifficile) |
PF03180(Lipoprotein_9) | 5 | VAL A 261ILE A 253LEU A 43GLY A 41ALA A 35 | None | 1.18A | 2xf3A-4oteA:undetectable | 2xf3A-4oteA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppm | AMINOTRANSFERASE (Serratia sp.FS14) |
PF00202(Aminotran_3) | 5 | VAL A 591ILE A 585LEU A 827GLY A 626ALA A 707 | None | 1.18A | 2xf3A-4ppmA:undetectable | 2xf3A-4ppmA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxd | ALLANTOATEAMIDOHYDROLASE (Escherichiacoli) |
PF01546(Peptidase_M20) | 5 | VAL A 75ILE A 183LEU A 400GLY A 79ALA A 100 | None | 0.96A | 2xf3A-4pxdA:undetectable | 2xf3A-4pxdA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q8g | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2 (Saccharomycescerevisiae) |
PF13423(UCH_1) | 5 | ILE A 675LEU A 731LEU A 673ALA A 769LYS A 768 | None | 1.20A | 2xf3A-4q8gA:undetectable | 2xf3A-4q8gA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9o | PUTATIVE ALDO/KETOREDUCTASE (Salmonellaenterica) |
PF00248(Aldo_ket_red) | 5 | VAL A 49ILE A 80LEU A 117GLY A 65ALA A 63 | None | 1.09A | 2xf3A-4r9oA:undetectable | 2xf3A-4r9oA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rg1 | C9ORF114 (Homo sapiens) |
PF02598(Methyltrn_RNA_3) | 5 | VAL A 77ILE A 112LEU A 96LEU A 146GLY A 98 | None | 1.28A | 2xf3A-4rg1A:undetectable | 2xf3A-4rg1A:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w9u | ACYL-COADEHYDROGENASE (Brucellaabortus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | VAL A 329LEU A 261ARG A 87GLY A 259ALA A 86 | None | 1.21A | 2xf3A-4w9uA:undetectable | 2xf3A-4w9uA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy4 | SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 (Homo sapiens) |
PF12352(V-SNARE_C)no annotation | 5 | VAL C 75ILE D 219LEU C 64LEU D 216GLY D 212 | None | 1.21A | 2xf3A-4wy4C:undetectable | 2xf3A-4wy4C:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 5 | VAL A 149LEU A 21ARG A 22GLY A 19ALA A 107 | None | 1.03A | 2xf3A-4x4jA:undetectable | 2xf3A-4x4jA:26.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0x | SERINE/THREONINE-PROTEIN KINASE PKNG (Mycobacteriumtuberculosis) |
PF00069(Pkinase)PF16919(PknG_rubred) | 5 | VAL A 395ILE A 254LEU A 353LEU A 335GLY A 332 | None | 1.27A | 2xf3A-4y0xA:undetectable | 2xf3A-4y0xA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y63 | HISTO-BLOOD GROUPABO SYSTEMTRANSFERASE (Homo sapiens) |
PF03414(Glyco_transf_6) | 5 | VAL A 277LEU A 324LEU A 306GLY A 267ALA A 268 | None | 1.19A | 2xf3A-4y63A:undetectable | 2xf3A-4y63A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zlv | ORNITHINEAMINOTRANSFERASE,MITOCHONDRIAL,PUTATIVE (Toxoplasmagondii) |
PF00202(Aminotran_3) | 5 | VAL A 232ILE A 226LEU A 414GLY A 267ALA A 343 | None | 1.12A | 2xf3A-4zlvA:1.5 | 2xf3A-4zlvA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7y | TRNA(ADENINE(9)-N1)-METHYLTRANSFERASE (Sulfolobusacidocaldarius) |
no annotation | 5 | ILE A 33LEU A 37ARG A 140GLY A 139ALA A 141 | None | 1.17A | 2xf3A-5a7yA:undetectable | 2xf3A-5a7yA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5avo | HOMOSERINEDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | VAL A 147ILE A 269LEU A 267GLY A 152ALA A 237 | None | 1.24A | 2xf3A-5avoA:undetectable | 2xf3A-5avoA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fjp | O-SUCCINYLBENZOATESYNTHASE (Amycolatopsissp.) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | TRP A 168VAL A 188ILE A 164LEU A 146ALA A 175 | None | 1.27A | 2xf3A-5fjpA:undetectable | 2xf3A-5fjpA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7d | PUTRESCINEAMINOTRANSFERASE,IMMUNOGLOBULING-BINDING PROTEIN A (Escherichiacoli;Staphylococcusaureus) |
PF00202(Aminotran_3)PF02216(B) | 5 | VAL A 246ILE A 240LEU A 431GLY A 281ALA A 359 | None | 1.12A | 2xf3A-5h7dA:undetectable | 2xf3A-5h7dA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k47 | POLYCYSTIN-2 (Homo sapiens) |
PF08016(PKD_channel) | 5 | VAL A 350LEU A 374LEU A 324ARG A 322GLY A 390 | NoneNAG A 803 (-4.8A)NoneNoneNone | 1.23A | 2xf3A-5k47A:undetectable | 2xf3A-5k47A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5npu | ANC27 (syntheticconstruct) |
no annotation | 5 | HIS A 21VAL A 70ILE A 97LEU A 9GLY A 6 | None | 1.14A | 2xf3A-5npuA:undetectable | 2xf3A-5npuA:11.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o1m | RUBBER OXYGENASE (Streptomycessp. K30) |
PF09995(DUF2236) | 5 | ILE A 323LEU A 390LEU A 136GLY A 135ALA A 169 | None | 1.20A | 2xf3A-5o1mA:undetectable | 2xf3A-5o1mA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1o | GLUTATHIONEREDUCTASE (Vibrioparahaemolyticus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 354LEU A 199LEU A 207GLY A 180ALA A 183 | None | 1.16A | 2xf3A-5u1oA:undetectable | 2xf3A-5u1oA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj7 | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF00004(AAA)PF09079(Cdc6_C) | 5 | VAL A 746ILE A 705LEU A 723LEU A 694ALA A 499 | None | 0.83A | 2xf3A-5uj7A:undetectable | 2xf3A-5uj7A:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujm | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF00004(AAA)PF09079(Cdc6_C) | 5 | ILE A 767LEU A 805LEU A 858ARG A 779ALA A 780 | None | 1.27A | 2xf3A-5ujmA:undetectable | 2xf3A-5ujmA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujm | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF00004(AAA)PF09079(Cdc6_C) | 5 | VAL A 746ILE A 705LEU A 723LEU A 694ALA A 499 | None | 0.84A | 2xf3A-5ujmA:undetectable | 2xf3A-5ujmA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v36 | GLUTATHIONEREDUCTASE (Streptococcusmutans) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 349LEU A 195LEU A 203GLY A 176ALA A 179 | NoneNoneNoneSO4 A 513 ( 3.9A)None | 1.15A | 2xf3A-5v36A:undetectable | 2xf3A-5v36A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vdn | GLUTATHIONEOXIDOREDUCTASE (Yersinia pestis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 359LEU A 205LEU A 213GLY A 186ALA A 189 | None | 1.14A | 2xf3A-5vdnA:undetectable | 2xf3A-5vdnA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbl | REGULATORY-ASSOCIATED PROTEIN OF TOR 1 (Arabidopsisthaliana) |
no annotation | 5 | ILE A 693LEU A 595LEU A 665GLY A 634ALA A 637 | None | 1.15A | 2xf3A-5wblA:2.3 | 2xf3A-5wblA:9.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxo | PERIPLASMICBETA-GLUCOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | ILE A 418LEU A 573LEU A 451GLY A 587ALA A 589 | None | 1.24A | 2xf3A-5xxoA:undetectable | 2xf3A-5xxoA:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ynl | ARGINASE (Glaciozymaantarctica) |
no annotation | 5 | HIS A 137ILE A 193LEU A 190GLY A 189ALA A 246 | None | 1.26A | 2xf3A-5ynlA:undetectable | 2xf3A-5ynlA:11.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6brd | RIFAMPINMONOOXYGENASE (Streptomycesvenezuelae) |
no annotation | 5 | VAL A 148LEU A 20ARG A 21GLY A 18ALA A 109 | None | 1.00A | 2xf3A-6brdA:undetectable | 2xf3A-6brdA:11.40 |