SIMILAR PATTERNS OF AMINO ACIDS FOR 2XDC_C_DVAC6

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gi2 CROTONYL-COA
CARBOXYLASE/REDUCTAS
E

(Methylobacterium
extorquens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ALA A 313
VAL A 317
TRP A 217
TRP A 282
 None
 1.01A 2xdcC-4gi2A:
undetectable
2xdcD-4gi2A:
undetectable		 2xdcC-4gi2A:
5.09
2xdcD-4gi2A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxn UNCHARACTERIZED
PROTEIN

(Zea mays) 		PF00171
(Aldedh) 		4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.32A 2xdcC-4pxnA:
undetectable
2xdcD-4pxnA:
undetectable		 2xdcC-4pxnA:
2.60
2xdcD-4pxnA:
2.60