SIMILAR PATTERNS OF AMINO ACIDS FOR 2X45_C_HSMC1161
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gom | ENDO-1,4-BETA-XYLANASE (Thermoascusaurantiacus) |
PF00331(Glyco_hydro_10) | 4 | VAL A 251TYR A 248VAL A 240ASP A 239 | None | 1.31A | 2x45C-1gomA:undetectable | 2x45C-1gomA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpl | RP2 LIPASE (Cavia porcellus) |
PF00151(Lipase)PF01477(PLAT) | 4 | VAL A 422VAL A 392ASP A 391SER A 388 | None | 1.27A | 2x45C-1gplA:0.0 | 2x45C-1gplA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1laj | CAPSID PROTEIN (Tomato aspermyvirus) |
PF00760(Cucumo_coat) | 4 | VAL A 186TYR A 187ASP A 190SER A 119 | None | 1.20A | 2x45C-1lajA:0.0 | 2x45C-1lajA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 4 | TYR D 405VAL D 415ASP D 414SER D 428 | None | 0.70A | 2x45C-1mhzD:undetectable | 2x45C-1mhzD:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mjf | SPERMIDINE SYNTHASE (Pyrococcusfuriosus) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | VAL A 34TYR A 23VAL A 112ASP A 115 | None | 1.09A | 2x45C-1mjfA:0.0 | 2x45C-1mjfA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9g | RRNAMETHYLTRANSFERASE (Streptomycesviridochromogenes) |
PF11599(AviRa) | 4 | VAL A 221VAL A 212ASP A 214SER A 236 | None | 0.95A | 2x45C-1o9gA:0.0 | 2x45C-1o9gA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q9j | POLYKETIDE SYNTHASEASSOCIATED PROTEIN 5 (Mycobacteriumtuberculosis) |
PF00668(Condensation)PF16911(PapA_C) | 4 | VAL A 413TYR A 417VAL A 301ASP A 302 | None | 1.13A | 2x45C-1q9jA:0.0 | 2x45C-1q9jA:13.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rmg | RHAMNOGALACTURONASEA (Aspergillusaculeatus) |
PF00295(Glyco_hydro_28) | 4 | VAL A 241TYR A 238VAL A 200SER A 219 | None | 1.28A | 2x45C-1rmgA:0.0 | 2x45C-1rmgA:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tjy | SUGAR TRANSPORTPROTEIN (Salmonellaenterica) |
PF13407(Peripla_BP_4) | 4 | VAL A 278TYR A 126VAL A 304ASP A 292 | None | 1.29A | 2x45C-1tjyA:0.0 | 2x45C-1tjyA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tnr | TUMOR NECROSISFACTOR BETA (Homo sapiens) |
PF00229(TNF) | 4 | VAL A 75TYR A 73VAL A 67ASP A 145 | None | 1.26A | 2x45C-1tnrA:undetectable | 2x45C-1tnrA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ued | P450 MONOOXYGENASE (Amycolatopsisorientalis) |
PF00067(p450) | 4 | VAL A 64TYR A 61ASP A 346SER A 290 | None | 1.34A | 2x45C-1uedA:undetectable | 2x45C-1uedA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1us2 | ENDO-BETA-1,4-XYLANASE (Cellvibriojaponicus) |
PF00331(Glyco_hydro_10)PF03426(CBM_15) | 4 | VAL A 533TYR A 530VAL A 500ASP A 499 | None | 1.29A | 2x45C-1us2A:undetectable | 2x45C-1us2A:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v2x | TRNA (GM18)METHYLTRANSFERASE (Thermusthermophilus) |
PF00588(SpoU_methylase)PF12105(SpoU_methylas_C) | 4 | VAL A 119TYR A 97VAL A 111ASP A 112 | None | 1.16A | 2x45C-1v2xA:undetectable | 2x45C-1v2xA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w2w | 5-METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE (Saccharomycescerevisiae) |
PF01008(IF-2B) | 4 | VAL A 140TYR A 137VAL A 16ASP A 9 | None | 1.17A | 2x45C-1w2wA:undetectable | 2x45C-1w2wA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bkl | PROLYL ENDOPEPTIDASE (Myxococcusxanthus) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 4 | VAL A 286TYR A 275VAL A 268ASP A 253 | None | 1.30A | 2x45C-2bklA:undetectable | 2x45C-2bklA:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dmy | SPERMATIDPERINUCLEARRNA-BINDING PROTEIN (Homo sapiens) |
PF00035(dsrm) | 4 | VAL A 73TYR A 59VAL A 54ASP A 53 | None | 1.09A | 2x45C-2dmyA:undetectable | 2x45C-2dmyA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eq9 | PYRUVATEDEHYDROGENASECOMPLEX,DIHYDROLIPOAMIDEDEHYDROGENASE E3COMPONENT (Thermusthermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | VAL A 252TYR A 243VAL A 163ASP A 162 | None | 1.16A | 2x45C-2eq9A:undetectable | 2x45C-2eq9A:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2etv | IRON(III) ABCTRANSPORTER,PERIPLASMICIRON-BINDINGPROTEIN, PUTATIVE (Thermotogamaritima) |
PF01497(Peripla_BP_2) | 4 | TYR A 212VAL A 194ASP A 250SER A 207 | NoneNoneNoneMLY A 232 ( 4.6A) | 1.26A | 2x45C-2etvA:undetectable | 2x45C-2etvA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exu | TRANSCRIPTIONINITIATION PROTEINSPT4/SPT5 (Saccharomycescerevisiae) |
PF03439(Spt5-NGN)PF06093(Spt4) | 4 | VAL A 50TYR A 74VAL A 66SER A 58 | None | 1.11A | 2x45C-2exuA:undetectable | 2x45C-2exuA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fo5 | CYSTEINE PROTEINASEEP-B 2 (Hordeum vulgare) |
PF00112(Peptidase_C1) | 4 | VAL A 138TYR A 221VAL A 121ASP A 128 | None | 1.22A | 2x45C-2fo5A:undetectable | 2x45C-2fo5A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jc6 | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE 1D (Homo sapiens) |
PF00069(Pkinase) | 4 | VAL A 192TYR A 198ASP A 203SER A 206 | None | 1.33A | 2x45C-2jc6A:undetectable | 2x45C-2jc6A:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjd | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE EPSILON (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | VAL A 686TYR A 683VAL A 658ASP A 657 | None | 1.31A | 2x45C-2jjdA:undetectable | 2x45C-2jjdA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n7g | POTASSIUMVOLTAGE-GATEDCHANNEL SUBFAMILY HMEMBER 2 (Homo sapiens) |
PF00027(cNMP_binding) | 4 | TYR A 70VAL A 60ASP A 64SER A 108 | None | 1.35A | 2x45C-2n7gA:undetectable | 2x45C-2n7gA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ood | BLR3880 PROTEIN (Bradyrhizobiumdiazoefficiens) |
PF01979(Amidohydro_1) | 4 | TYR A 464VAL A 453ASP A 450SER A 334 | None | 1.25A | 2x45C-2oodA:undetectable | 2x45C-2oodA:14.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ozu | HISTONEACETYLTRANSFERASEMYST3 (Homo sapiens) |
PF01853(MOZ_SAS) | 4 | VAL A 617TYR A 616ASP A 582SER A 586 | None | 1.21A | 2x45C-2ozuA:undetectable | 2x45C-2ozuA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p8t | HYPOTHETICAL PROTEINPH0730 (Pyrococcushorikoshii) |
PF14544(DUF4443) | 4 | VAL A 101TYR A 158VAL A 130ASP A 160 | None | 1.26A | 2x45C-2p8tA:undetectable | 2x45C-2p8tA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgq | DOMAIN OF UNKNOWNFUNCTION WITH ACYSTATIN-LIKE FOLD (Nostocpunctiforme) |
PF13577(SnoaL_4) | 4 | VAL A 92VAL A 126ASP A 127SER A 129 | None | 1.27A | 2x45C-2rgqA:undetectable | 2x45C-2rgqA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2tnf | PROTEIN (TUMORNECROSIS FACTORALPHA) (Mus musculus) |
PF00229(TNF) | 4 | VAL A 58TYR A 56VAL A 50ASP A 130 | None | 1.30A | 2x45C-2tnfA:undetectable | 2x45C-2tnfA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vc2 | INTEGRIN ALPHA-IIB (Homo sapiens) |
PF01839(FG-GAP)PF13517(VCBS) | 4 | VAL A 241TYR A 253VAL A 182SER A 172 | None | 1.25A | 2x45C-2vc2A:undetectable | 2x45C-2vc2A:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w7w | SUPEROXIDE DISMUTASE[FE] (Aliivibriosalmonicida) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TYR A 175VAL A 157ASP A 158SER A 122 | NoneNone FE A1195 (-2.5A)None | 1.24A | 2x45C-2w7wA:undetectable | 2x45C-2w7wA:21.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x46 | ALLERGEN ARG R 1 (Argas reflexus) |
PF02098(His_binding) | 4 | VAL A 53TYR A 69VAL A 94ASP A 97 | TRS A1160 (-4.1A)NoneNoneNone | 0.92A | 2x45C-2x46A:29.4 | 2x45C-2x46A:99.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x46 | ALLERGEN ARG R 1 (Argas reflexus) |
PF02098(His_binding) | 4 | VAL A 53TYR A 69VAL A 94SER A 99 | TRS A1160 (-4.1A)NoneNoneNone | 0.71A | 2x45C-2x46A:29.4 | 2x45C-2x46A:99.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 4 | VAL A 576TYR A 584ASP A 758SER A 797 | None | 1.35A | 2x45C-2zxqA:undetectable | 2x45C-2zxqA:7.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3h | ENDOGLUCANASE (Salipaludibacillusagaradhaerens) |
PF00150(Cellulase) | 4 | VAL A 60TYR A 95VAL A 5ASP A 93 | None | 1.28A | 2x45C-3a3hA:undetectable | 2x45C-3a3hA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abz | BETA-GLUCOSIDASE I (Kluyveromycesmarxianus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF07691(PA14)PF14310(Fn3-like) | 4 | VAL A 529TYR A 467VAL A 554SER A 440 | None | 1.15A | 2x45C-3abzA:undetectable | 2x45C-3abzA:10.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3af5 | PUTATIVEUNCHARACTERIZEDPROTEIN PH1404 (Pyrococcushorikoshii) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | VAL A 390VAL A 216ASP A 217SER A 203 | None | 1.29A | 2x45C-3af5A:undetectable | 2x45C-3af5A:10.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b0h | NITRITE REDUCTASE (Nicotianatabacum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | VAL A 229TYR A 200VAL A 195ASP A 196 | None | 1.32A | 2x45C-3b0hA:undetectable | 2x45C-3b0hA:13.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bu1 | LIPOCALIN (Argasmonolakensis) |
PF02098(His_binding) | 5 | VAL A 37TYR A 53VAL A 78ASP A 81SER A 83 | NoneNoneNoneNoneHSM A 301 ( 4.0A) | 0.53A | 2x45C-3bu1A:25.9 | 2x45C-3bu1A:48.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cpq | 50S RIBOSOMALPROTEIN L30E (Methanocaldococcusjannaschii) |
PF01248(Ribosomal_L7Ae) | 4 | VAL A 42TYR A 67VAL A 9SER A 97 | None | 1.11A | 2x45C-3cpqA:undetectable | 2x45C-3cpqA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ed4 | ARYLSULFATASE (Escherichiacoli) |
PF00884(Sulfatase) | 4 | TYR A 285VAL A 241ASP A 52SER A 318 | NoneNone NA A 519 (-3.0A)None | 1.26A | 2x45C-3ed4A:undetectable | 2x45C-3ed4A:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewr | NON-STRUCTURALPROTEIN 3 (Humancoronavirus229E) |
PF01661(Macro) | 4 | VAL A 52TYR A 53VAL A 20ASP A 19 | NoneNoneAPR A 169 (-4.3A)None | 1.33A | 2x45C-3ewrA:undetectable | 2x45C-3ewrA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgb | UNCHARACTERIZEDPROTEIN Q89ZH8_BACTN (Bacteroidesthetaiotaomicron) |
PF10282(Lactonase) | 4 | VAL A 40TYR A 52VAL A 373ASP A 374 | None | 1.20A | 2x45C-3fgbA:undetectable | 2x45C-3fgbA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g25 | GLYCEROL KINASE (Staphylococcusaureus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | VAL A 425VAL A 402ASP A 401SER A 395 | None | 1.30A | 2x45C-3g25A:undetectable | 2x45C-3g25A:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hid | ADENYLOSUCCINATESYNTHETASE (Yersinia pestis) |
PF00709(Adenylsucc_synt) | 4 | VAL A 403VAL A 316ASP A 312SER A 271 | None | 1.07A | 2x45C-3hidA:undetectable | 2x45C-3hidA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuu | PUTATIVEMETALLOPEPTIDASE (Chelativoranssp. BNC1) |
PF07171(MlrC_C)PF07364(DUF1485) | 4 | VAL A 232VAL A 238ASP A 237SER A 17 | None | 1.33A | 2x45C-3iuuA:undetectable | 2x45C-3iuuA:13.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxa | CONTACTIN 4 (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 4 | VAL A 79TYR A 77VAL A 69ASP A 70 | None | 1.28A | 2x45C-3jxaA:undetectable | 2x45C-3jxaA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l5h | INTERLEUKIN-6RECEPTOR SUBUNITBETA (Homo sapiens) |
PF00041(fn3)PF06328(Lep_receptor_Ig)PF09240(IL6Ra-bind) | 4 | TYR A 555VAL A 548ASP A 549SER A 551 | None | 1.15A | 2x45C-3l5hA:undetectable | 2x45C-3l5hA:12.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ljf | IRON SUPEROXIDEDISMUTASE (Pseudoalteromonashaloplanktis) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TYR A 174VAL A 156ASP A 157SER A 121 | NoneNone FE A5000 (-2.6A)None | 1.27A | 2x45C-3ljfA:undetectable | 2x45C-3ljfA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m9q | PROTEINMALE-SPECIFICLETHAL-3 (Drosophilamelanogaster) |
no annotation | 4 | VAL A 67TYR A 52VAL A 35SER A 33 | None | 1.27A | 2x45C-3m9qA:undetectable | 2x45C-3m9qA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mfn | UNCHARACTERIZEDPROTEIN (Dyadobacterfermentans) |
no annotation | 4 | VAL A 44TYR A 38VAL A 113ASP A 109 | None | 1.05A | 2x45C-3mfnA:undetectable | 2x45C-3mfnA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 4 | VAL A 488TYR A 485VAL A 480ASP A 481 | None | 0.90A | 2x45C-3r75A:undetectable | 2x45C-3r75A:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugk | SACCHAROPINEDEHYDROGENASE [NAD+,L-LYSINE-FORMING] (Saccharomycescerevisiae) |
PF05222(AlaDh_PNT_N) | 4 | VAL A 305VAL A 275ASP A 277SER A 317 | None | 1.31A | 2x45C-3ugkA:undetectable | 2x45C-3ugkA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4p | INTEGRIN ALPHA-4 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | VAL A 353TYR A 370VAL A 306SER A 276 | None | 1.21A | 2x45C-3v4pA:undetectable | 2x45C-3v4pA:13.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgf | MALTO-OLIGOSYLTREHALOSE TREHALOHYDROLASE (Sulfolobussolfataricus) |
PF00128(Alpha-amylase)PF09071(Alpha-amyl_C) | 4 | VAL A 361VAL A 307ASP A 309SER A 338 | None | 1.29A | 2x45C-3vgfA:undetectable | 2x45C-3vgfA:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vly | NITRITE REDUCTASE (Nicotianatabacum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | VAL A 229TYR A 200VAL A 195ASP A 196 | None | 1.31A | 2x45C-3vlyA:undetectable | 2x45C-3vlyA:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxm | PROTEIN PELOTAHOMOLOG (Aeropyrumpernix) |
PF03463(eRF1_1)PF03465(eRF1_3) | 4 | VAL B 175TYR B 174VAL B 134ASP B 135 | None | 1.22A | 2x45C-3wxmB:undetectable | 2x45C-3wxmB:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a8j | ELONGATOR COMPLEXPROTEIN 5 (Saccharomycescerevisiae) |
PF10483(Elong_Iki1) | 4 | VAL B 184VAL B 173ASP B 172SER B 30 | None | 0.96A | 2x45C-4a8jB:undetectable | 2x45C-4a8jB:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 4 | VAL A 467VAL A 400ASP A 399SER A 309 | None | 1.12A | 2x45C-4aioA:undetectable | 2x45C-4aioA:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ang | COAT PROTEIN (Pseudomonasphage PRR1) |
PF01819(Levi_coat) | 4 | VAL A 106VAL A 89ASP A 90SER A 59 | None | 1.33A | 2x45C-4angA:undetectable | 2x45C-4angA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cu8 | GLYCOSIDE HYDROLASE2 (Streptococcuspneumoniae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 4 | VAL A 365TYR A 351VAL A 333ASP A 381 | NoneNoneEDO A2001 (-4.8A)EDO A2001 (-4.1A) | 1.13A | 2x45C-4cu8A:undetectable | 2x45C-4cu8A:10.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d9r | COMPLEMENT FACTOR D (Homo sapiens) |
PF00089(Trypsin) | 4 | VAL A 45TYR A 29VAL A 200ASP A 137 | None | 1.10A | 2x45C-4d9rA:undetectable | 2x45C-4d9rA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6a | BH1408 PROTEIN (Bacillushalodurans) |
PF00583(Acetyltransf_1) | 4 | VAL A 89TYR A 90ASP A 93SER A 70 | None | 1.16A | 2x45C-4f6aA:undetectable | 2x45C-4f6aA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl0 | AMINOTRANSFERASEALD1 (Arabidopsisthaliana) |
PF00155(Aminotran_1_2) | 4 | VAL A 192TYR A 189VAL A 174ASP A 171 | None | 1.07A | 2x45C-4fl0A:undetectable | 2x45C-4fl0A:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gwr | PROTEINDISULFIDE-ISOMERASEA6 (Homo sapiens) |
PF00085(Thioredoxin) | 4 | VAL A 183VAL A 174ASP A 171SER A 169 | None | 1.14A | 2x45C-4gwrA:undetectable | 2x45C-4gwrA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4idj | FAB HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL H 121VAL H 150ASP H 199SER H 153 | None | 1.07A | 2x45C-4idjH:undetectable | 2x45C-4idjH:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ig7 | UBIQUITIN C-TERMINALHYDROLASE 37 (Trichinellaspiralis) |
PF01088(Peptidase_C12) | 4 | VAL A 166TYR A 173VAL A 74ASP A 73 | None | 1.23A | 2x45C-4ig7A:undetectable | 2x45C-4ig7A:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4isb | LONG CHAIN FATTYACID COA LIGASEFADD10 (Mycobacteriumtuberculosis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | VAL A 291TYR A 293VAL A 303ASP A 302 | None | 1.23A | 2x45C-4isbA:undetectable | 2x45C-4isbA:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozu | CORONIN (Toxoplasmagondii) |
PF00400(WD40)PF08953(DUF1899)PF16300(WD40_4) | 4 | VAL A 390TYR A 362VAL A 323ASP A 324 | None | 1.02A | 2x45C-4ozuA:undetectable | 2x45C-4ozuA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvg | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 11 (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | VAL A 518TYR A 515VAL A 490ASP A 489 | None | 1.25A | 2x45C-4pvgA:undetectable | 2x45C-4pvgA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1v | PUTATIVE DIPEPTIDYLAMINOPEPTIDASE IV (Bacteroidesovatus) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | VAL A 228TYR A 230VAL A 682ASP A 678 | None | 1.31A | 2x45C-4q1vA:undetectable | 2x45C-4q1vA:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3a | BLUE-LIGHT-ACTIVATEDHISTIDINE KINASE 2 (Erythrobacterlitoralis) |
PF07568(HisKA_2)PF13426(PAS_9)PF13581(HATPase_c_2) | 4 | VAL A 232VAL A 270ASP A 228SER A 268 | None | 1.08A | 2x45C-4r3aA:undetectable | 2x45C-4r3aA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xax | CARD (Thermusthermophilus) |
PF02559(CarD_CdnL_TRCF) | 4 | VAL B 49TYR B 36VAL B 20ASP B 8 | None | 1.29A | 2x45C-4xaxB:undetectable | 2x45C-4xaxB:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcm | CELL WALL-BINDINGENDOPEPTIDASE-RELATED PROTEIN (Thermusthermophilus) |
PF00877(NLPC_P60)PF01476(LysM) | 4 | VAL A 159TYR A 163VAL A 244ASP A 191 | None | 1.29A | 2x45C-4xcmA:undetectable | 2x45C-4xcmA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xr7 | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3 (Saccharomycescerevisiae) |
no annotation | 4 | VAL L 313TYR L 322VAL L 374ASP L 359 | None | 1.30A | 2x45C-4xr7L:undetectable | 2x45C-4xr7L:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6s | ENDOLYSIN (Clostridiumphage phiCTP1) |
PF01183(Glyco_hydro_25) | 4 | VAL A 90TYR A 59ASP A 177SER A 179 | NoneSO4 A1274 (-4.5A)SO4 A1274 (-3.4A)None | 0.62A | 2x45C-5a6sA:undetectable | 2x45C-5a6sA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5axh | DEXTRANASE (Thermoanaerobacterpseudethanolicus) |
PF13199(Glyco_hydro_66) | 4 | VAL A 404TYR A 152VAL A 350ASP A 369 | None | 1.24A | 2x45C-5axhA:undetectable | 2x45C-5axhA:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c4q | BROMODOMAIN (Leishmaniadonovani) |
PF00439(Bromodomain) | 4 | VAL A 48TYR A 45VAL A 36ASP A 53 | NoneUNX A 203 ( 4.4A)BMF A 201 (-4.6A)None | 1.31A | 2x45C-5c4qA:undetectable | 2x45C-5c4qA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ei0 | SERPIN A12 (Homo sapiens) |
PF00079(Serpin) | 4 | VAL A 249TYR A 247VAL A 306ASP A 305 | None | 1.09A | 2x45C-5ei0A:undetectable | 2x45C-5ei0A:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ful | PROTEIN ARGININEN-METHYLTRANSFERASE2 (Mus musculus) |
PF05175(MTS) | 4 | VAL A 140TYR A 137VAL A 221ASP A 155 | NoneNoneNoneSAH A1446 ( 4.5A) | 1.32A | 2x45C-5fulA:undetectable | 2x45C-5fulA:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ggg | PROTEINO-LINKED-MANNOSEBETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE1 (Homo sapiens) |
PF03071(GNT-I)PF15711(ILEI) | 4 | VAL A 278TYR A 275VAL A 347ASP A 346 | None | 1.03A | 2x45C-5gggA:undetectable | 2x45C-5gggA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gin | C/D BOX METHYLATIONGUIDERIBONUCLEOPROTEINCOMPLEX ANOP56SUBUNIT (Sulfolobussolfataricus) |
PF01798(Nop) | 4 | VAL A 14TYR A 25ASP A 103SER A 96 | None | 1.28A | 2x45C-5ginA:undetectable | 2x45C-5ginA:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gjn | LYSINE/ORNITHINEDECARBOXYLASE (Selenomonasruminantium) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | VAL A 110TYR A 92VAL A 71ASP A 70 | None | 1.32A | 2x45C-5gjnA:undetectable | 2x45C-5gjnA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtk | BETAINE-ALDEHYDEDEHYDROGENASE (Bacillus cereus) |
PF00171(Aldedh) | 4 | VAL A 308TYR A 313VAL A 317ASP A 318 | None | 1.26A | 2x45C-5gtkA:undetectable | 2x45C-5gtkA:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6v | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 11 (Homo sapiens) |
PF00017(SH2)PF00102(Y_phosphatase) | 4 | VAL A 518TYR A 515VAL A 490ASP A 489 | None | 1.22A | 2x45C-5i6vA:undetectable | 2x45C-5i6vA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jc8 | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Paraburkholderiaxenovorans) |
PF13561(adh_short_C2) | 4 | VAL A 44VAL A 72ASP A 71SER A 77 | None | 1.27A | 2x45C-5jc8A:undetectable | 2x45C-5jc8A:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lb3 | ATP-DEPENDENT DNAHELICASE Q5 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF16124(RecQ_Zn_bind) | 4 | VAL B 162TYR B 173VAL B 156ASP B 157 | NoneNoneNone MG B 503 ( 4.0A) | 1.10A | 2x45C-5lb3B:undetectable | 2x45C-5lb3B:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lb8 | ATP-DEPENDENT DNAHELICASE Q5 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF16124(RecQ_Zn_bind) | 4 | VAL A 162TYR A 173VAL A 156ASP A 157 | None | 1.33A | 2x45C-5lb8A:undetectable | 2x45C-5lb8A:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lmc | ANAEROBIC NITRICOXIDE REDUCTASEFLAVORUBREDOXIN (Escherichiacoli) |
PF00258(Flavodoxin_1)PF00301(Rubredoxin)PF00753(Lactamase_B) | 4 | VAL A 76TYR A 101VAL A 124ASP A 128 | None | 1.33A | 2x45C-5lmcA:undetectable | 2x45C-5lmcA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msw | THIOESTER REDUCTASEDOMAIN-CONTAININGPROTEIN (Segniliparusrugosus) |
PF00501(AMP-binding)PF00550(PP-binding) | 4 | VAL A 458TYR A 463VAL A 508ASP A 521 | None | 1.29A | 2x45C-5mswA:undetectable | 2x45C-5mswA:7.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txk | UBIQUITINCARBOXYL-TERMINALHYDROLASE35,UBIQUITINCARBOXYL-TERMINALHYDROLASE 35 (Homo sapiens) |
no annotation | 4 | VAL A 850TYR A 866VAL A 909ASP A 916 | None | 0.87A | 2x45C-5txkA:undetectable | 2x45C-5txkA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhe | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA' (Mycobacteriumtuberculosis) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | VAL D 965TYR D 979VAL D 995SER D 881 | None | 1.27A | 2x45C-5uheD:undetectable | 2x45C-5uheD:6.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5up2 | N-METHYL-D-ASPARTATERECEPTOR SUBUNITNR2A (Xenopus laevis) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | VAL B 701VAL B 722ASP B 719SER B 499 | None | 1.29A | 2x45C-5up2B:undetectable | 2x45C-5up2B:10.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xon | TRANSCRIPTIONELONGATION FACTORSPT4 (Komagataellaphaffii) |
PF06093(Spt4) | 4 | VAL V 58TYR V 82VAL V 74SER V 66 | None | 1.12A | 2x45C-5xonV:undetectable | 2x45C-5xonV:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xya | - (-) |
no annotation | 4 | VAL A1527TYR A1526VAL A1002ASP A 587 | None | 1.28A | 2x45C-5xyaA:undetectable | 2x45C-5xyaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 4 | VAL A 530TYR A 529VAL A 426SER A 391 | None | 1.21A | 2x45C-5zl9A:undetectable | 2x45C-5zl9A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6acd | - (-) |
no annotation | 4 | VAL A 496TYR A 494VAL A 394ASP A 392 | None | 1.18A | 2x45C-6acdA:undetectable | 2x45C-6acdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c4n | PSEUDOPALINEDEHYDROGENASE (Pseudomonasaeruginosa) |
no annotation | 4 | VAL A 122TYR A 150VAL A 23ASP A 26 | NoneNAP A 501 (-4.7A)NoneNone | 1.20A | 2x45C-6c4nA:undetectable | 2x45C-6c4nA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d4j | PROTEIN PATCHEDHOMOLOG 1 (Homo sapiens) |
no annotation | 4 | VAL A 477VAL A 510ASP A 513SER A1132 | None | 1.26A | 2x45C-6d4jA:undetectable | 2x45C-6d4jA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6en4 | SPLICING FACTOR 3BSUBUNIT 3 (Homo sapiens) |
no annotation | 4 | VAL A 959TYR A 970VAL A 925SER A 890 | None | 0.84A | 2x45C-6en4A:undetectable | 2x45C-6en4A:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6epd | PROTEASOME SUBUNITBETA TYPE-4 (Rattusnorvegicus) |
no annotation | 4 | VAL 7 219TYR 7 222VAL 7 55ASP 7 100 | None | 1.15A | 2x45C-6epd7:undetectable | 2x45C-6epd7:19.15 |