SIMILAR PATTERNS OF AMINO ACIDS FOR 2X45_B_HSMB1160

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bjn PHOSPHOSERINE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00266
(Aminotran_5) 		4 TYR A 193
VAL A 208
TYR A 228
ILE A  87
 None
 1.08A 2x45B-1bjnA:
undetectable		 2x45B-1bjnA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0i D-AMINO ACID OXIDASE

(Rhodotorula
toruloides) 		PF01266
(DAO) 		4 SER A1019
VAL A1294
ILE A1015
TRP A1070
 None
None
FAD  A1363 (-4.0A)
None
 1.25A 2x45B-1c0iA:
undetectable		 2x45B-1c0iA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cp2 NITROGENASE IRON
PROTEIN

(Clostridium
pasteurianum) 		PF00142
(Fer4_NifH) 		4 TYR A 121
VAL A 123
TYR A   7
ILE A 136
 None
 1.20A 2x45B-1cp2A:
0.0		 2x45B-1cp2A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ddg SULFITE REDUCTASE
(NADPH) FLAVOPROTEIN
ALPHA-COMPONENT

(Escherichia
coli) 		PF00175
(NAD_binding_1)
PF00667
(FAD_binding_1) 		4 SER A 367
TYR A 332
VAL A 329
TYR A 354
 None
 1.09A 2x45B-1ddgA:
undetectable		 2x45B-1ddgA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e8t HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.16A 2x45B-1e8tA:
0.2		 2x45B-1e8tA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5m GAF

(Saccharomyces
cerevisiae) 		PF13185
(GAF_2) 		4 VAL A  62
TYR A  57
ILE A 133
ASP A 159
 None
 1.04A 2x45B-1f5mA:
0.6		 2x45B-1f5mA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h54 MALTOSE
PHOSPHORYLASE

(Lactobacillus
brevis) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 VAL A 596
TYR A 619
ILE A 551
TRP A 496
 None
 1.10A 2x45B-1h54A:
undetectable		 2x45B-1h54A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jf5 ALPHA AMYLASE II

(Thermoactinomyces
vulgaris) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 VAL A 440
TYR A 487
ILE A 452
ASP A 418
 None
 1.21A 2x45B-1jf5A:
0.0		 2x45B-1jf5A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 SER A 149
TYR A 153
TYR A 179
ILE A 143
 None
 1.20A 2x45B-1lbkA:
undetectable		 2x45B-1lbkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhy METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox) 		4 SER B 168
ILE B 247
ASP B 172
TRP B 244
 None
 1.18A 2x45B-1mhyB:
undetectable		 2x45B-1mhyB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qsa PROTEIN (SOLUBLE
LYTIC
TRANSGLYCOSYLASE
SLT70)

(Escherichia
coli) 		PF01464
(SLT)
PF14718
(SLT_L) 		4 SER A 282
ILE A 279
ASP A 256
TRP A 260
 None
 0.95A 2x45B-1qsaA:
undetectable		 2x45B-1qsaA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 SER A 539
TYR A 371
ILE A 536
ASP A 614
 None
 1.21A 2x45B-1qvrA:
undetectable		 2x45B-1qvrA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tr1 BETA-GLUCOSIDASE A

(Paenibacillus
polymyxa) 		PF00232
(Glyco_hydro_1) 		4 SER A  57
VAL A 104
TYR A 100
ASP A  64
 None
 1.15A 2x45B-1tr1A:
undetectable		 2x45B-1tr1A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpl ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		4 TYR A  96
VAL A 132
TYR A 135
ILE A 128
 None
 1.23A 2x45B-1vplA:
undetectable		 2x45B-1vplA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1woi AGMATINASE

(Deinococcus
radiodurans) 		PF00491
(Arginase) 		4 SER A 124
TYR A 225
VAL A 139
ASP A 271
 None
 1.12A 2x45B-1woiA:
undetectable		 2x45B-1woiA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z9a NAD(P)H-DEPENDENT
D-XYLOSE REDUCTASE

([Candida]
tenuis) 		PF00248
(Aldo_ket_red) 		4 TYR A 107
VAL A 105
ILE A  76
ASP A 109
 None
 1.13A 2x45B-1z9aA:
undetectable		 2x45B-1z9aA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zzv IRON(III) DICITRATE
TRANSPORT PROTEIN
FECA

(Escherichia
coli) 		PF07660
(STN) 		4 SER A  48
TYR A  44
VAL A   3
TYR A  17
 None
 1.19A 2x45B-1zzvA:
undetectable		 2x45B-1zzvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2crw ADP-RIBOSYLATION
FACTOR
GTPASE-ACTIVATING
PROTEIN 3

(Homo sapiens) 		PF01412
(ArfGap) 		4 SER A  67
TYR A  47
VAL A  49
ILE A  69
 None
 1.25A 2x45B-2crwA:
undetectable		 2x45B-2crwA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvz PUTATIVE EXPORTED
PROTEIN

(Bordetella
pertussis) 		PF03401
(TctC) 		4 SER A 199
VAL A 241
TYR A 243
ASP A 195
 None
None
GLU  A1055 (-4.2A)
None
 1.13A 2x45B-2dvzA:
undetectable		 2x45B-2dvzA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2

(Homo sapiens) 		PF00179
(UQ_con) 		4 SER A 146
TYR A  61
VAL A  47
ILE A 167
 None
 1.24A 2x45B-2f4wA:
undetectable		 2x45B-2f4wA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A

(Archaeoglobus
fulgidus) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 SER A  83
VAL A 120
ILE A 146
ASP A  78
 None
 1.06A 2x45B-2fjaA:
undetectable		 2x45B-2fjaA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gai DNA TOPOISOMERASE I

(Thermotoga
maritima) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 SER A 150
TYR A 502
VAL A 505
ILE A 146
 None
 1.19A 2x45B-2gaiA:
undetectable		 2x45B-2gaiA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzs IROE PROTEIN

(Escherichia
coli) 		PF00756
(Esterase) 		4 SER A 210
VAL A 226
ILE A 241
TRP A 199
 None
 1.25A 2x45B-2gzsA:
undetectable		 2x45B-2gzsA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1r DIMETHYLADENOSINE
TRANSFERASE,
PUTATIVE

(Plasmodium
falciparum) 		PF00398
(RrnaAD) 		4 VAL A 131
TYR A 136
ILE A 141
ASP A 260
 None
 1.24A 2x45B-2h1rA:
undetectable		 2x45B-2h1rA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6t CANDIDAPEPSIN-3

(Candida
albicans) 		PF00026
(Asp) 		4 TYR A  65
VAL A  40
ILE A  99
ASP A  97
 None
 1.25A 2x45B-2h6tA:
undetectable		 2x45B-2h6tA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j04 HYPOTHETICAL PROTEIN
YPL007C

(Saccharomyces
cerevisiae) 		PF12660
(zf-TFIIIC) 		4 SER A 142
VAL A 111
ILE A 158
ASP A  97
 None
 0.95A 2x45B-2j04A:
undetectable		 2x45B-2j04A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lvv FLAGELLAR
CALCIUM-BINDING
PROTEIN TB-24

(Trypanosoma
brucei) 		PF13202
(EF-hand_5)
PF13499
(EF-hand_7) 		4 VAL A 197
TYR A 128
ILE A  93
ASP A 190
 None
 1.13A 2x45B-2lvvA:
undetectable		 2x45B-2lvvA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5p FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07660
(STN)
PF07715
(Plug) 		4 VAL A 197
TYR A 207
ILE A 185
ASP A 187
 None
None
None
PO4  A   3 (-4.0A)
 1.26A 2x45B-2o5pA:
undetectable		 2x45B-2o5pA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obe HEXON

(Human
mastadenovirus
E) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		4 TYR A 596
TYR A  83
ILE A 593
ASP A 101
 None
 1.25A 2x45B-2obeA:
undetectable		 2x45B-2obeA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe6 UNCHARACTERIZED
PROTEIN TFU_2867

(Thermobifida
fusca) 		PF04672
(Methyltransf_19) 		4 VAL A 177
TYR A 181
ILE A 142
ASP A 135
 None
None
None
SAM  A 400 (-3.4A)
 1.11A 2x45B-2qe6A:
undetectable		 2x45B-2qe6A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qml BH2621 PROTEIN

(Bacillus
halodurans) 		PF13523
(Acetyltransf_8) 		4 VAL A 168
TYR A  97
ILE A  93
ASP A 172
 None
 1.23A 2x45B-2qmlA:
1.7		 2x45B-2qmlA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5d O-GLCNACASE NAGJ

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C)
PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase) 		4 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.07A 2x45B-2v5dA:
undetectable		 2x45B-2v5dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8j PECTATE LYASE

(Yersinia
enterocolitica) 		PF06917
(Pectate_lyase_2) 		4 SER A  30
VAL A 112
TYR A  97
ASP A  22
 None
 1.14A 2x45B-2v8jA:
undetectable		 2x45B-2v8jA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbi ACYL-COA
DEHYDROGENASE FAMILY
MEMBER 11

(Homo sapiens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 SER A 325
VAL A 376
ILE A 322
TRP A 321
 None
 1.21A 2x45B-2wbiA:
undetectable		 2x45B-2wbiA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzs PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 SER A 387
TYR A  92
ILE A  89
ASP A 343
 None
 1.23A 2x45B-2wzsA:
undetectable		 2x45B-2wzsA:
11.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2x46 ALLERGEN ARG R 1

(Argas reflexus) 		PF02098
(His_binding) 		7 SER A  28
TYR A  37
VAL A  53
TYR A  67
ILE A  92
ASP A 110
TRP A 121
 TRS  A1160 (-2.7A)
TRS  A1160 (-3.4A)
TRS  A1160 (-4.1A)
TRS  A1160 (-4.7A)
None
TRS  A1160 (-3.0A)
TRS  A1160 (-3.3A)
 0.44A 2x45B-2x46A:
29.6		 2x45B-2x46A:
99.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xox PTERIDINE REDUCTASE

(Leishmania
donovani) 		PF00106
(adh_short)
PF13561
(adh_short_C2) 		4 SER A 266
VAL A 105
TYR A  31
ILE A 262
 None
 1.12A 2x45B-2xoxA:
undetectable		 2x45B-2xoxA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yy6 PHOSPHOGLYCOLATE
PHOSPHATASE

(Aquifex
aeolicus) 		PF13419
(HAD_2) 		4 SER A  15
TYR A  72
ILE A  19
ASP A   9
 None
 1.07A 2x45B-2yy6A:
undetectable		 2x45B-2yy6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2

(Arabidopsis
thaliana) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 VAL A 236
TYR A 250
ILE A 128
ASP A 130
 None
 1.13A 2x45B-2zvwA:
undetectable		 2x45B-2zvwA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b46 AMINOTRANSFERASE
BNA3

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		4 TYR A 351
VAL A 362
ILE A 343
ASP A 345
 None
 1.01A 2x45B-3b46A:
undetectable		 2x45B-3b46A:
15.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3brn LIPOCALIN

(Argas
monolakensis) 		PF02098
(His_binding) 		6 SER A  18
TYR A  27
VAL A  43
ILE A  82
ASP A 106
TRP A 118
 SRO  A 158 (-3.6A)
SRO  A 158 (-3.5A)
SRO  A 158 ( 4.6A)
SRO  A 158 (-4.4A)
SRO  A 158 (-3.2A)
SRO  A 158 (-3.3A)
 0.33A 2x45B-3brnA:
22.5		 2x45B-3brnA:
36.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bu1 LIPOCALIN

(Argas
monolakensis) 		PF02098
(His_binding) 		7 SER A  12
TYR A  21
VAL A  37
TYR A  51
ILE A  76
ASP A  94
TRP A 105
 HSM  A 301 (-3.6A)
HSM  A 301 (-3.2A)
None
HSM  A 301 (-4.6A)
HSM  A 301 ( 4.0A)
HSM  A 301 (-2.9A)
HSM  A 301 (-3.3A)
 0.34A 2x45B-3bu1A:
25.9		 2x45B-3bu1A:
48.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqn VIOLAXANTHIN
DE-EPOXIDASE,
CHLOROPLAST

(Arabidopsis
thaliana) 		PF07137
(VDE) 		4 TYR A 198
VAL A 196
ILE A 105
ASP A 114
 None
 1.23A 2x45B-3cqnA:
10.5		 2x45B-3cqnA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7x FEMALE-SPECIFIC
HISTAMINE-BINDING
PROTEIN 2

(Rhipicephalus
appendiculatus) 		PF02098
(His_binding) 		4 SER A  20
TYR A  29
ASP A 120
TRP A 137
 None
 0.81A 2x45B-3g7xA:
18.0		 2x45B-3g7xA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7x FEMALE-SPECIFIC
HISTAMINE-BINDING
PROTEIN 2

(Rhipicephalus
appendiculatus) 		PF02098
(His_binding) 		4 TYR A  29
VAL A  51
ASP A 120
TRP A 137
 None
 0.52A 2x45B-3g7xA:
18.0		 2x45B-3g7xA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hj4 MINOR
EDITOSOME-ASSOCIATED
TUTASE

(Trypanosoma
brucei) 		no annotation 4 SER A 266
VAL A 280
TYR A 339
ILE A 268
 None
 1.22A 2x45B-3hj4A:
undetectable		 2x45B-3hj4A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmc PUTATIVE PROPHAGE
LAMBDABA04, GLYCOSYL
HYDROLASE, FAMILY 25

(Bacillus
anthracis) 		PF01183
(Glyco_hydro_25) 		4 TYR A  61
VAL A  91
ILE A 159
ASP A   9
 MES  A 400 (-4.0A)
None
None
MES  A 400 ( 4.0A)
 1.22A 2x45B-3hmcA:
undetectable		 2x45B-3hmcA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxj PYRROLO-QUINOLINE
QUINONE

(Methanococcus
maripaludis) 		PF01011
(PQQ)
PF13360
(PQQ_2)
PF13570
(PQQ_3) 		4 TYR A 120
VAL A 112
ILE A 138
ASP A 116
 None
 1.24A 2x45B-3hxjA:
undetectable		 2x45B-3hxjA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kcm THIOREDOXIN FAMILY
PROTEIN

(Geobacter
metallireducens) 		PF00578
(AhpC-TSA) 		4 SER A  92
VAL A 131
ASP A  94
TRP A  63
 None
None
None
SO4  A   1 (-3.9A)
 1.26A 2x45B-3kcmA:
undetectable		 2x45B-3kcmA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqh GLYCOSYL HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF04616
(Glyco_hydro_43) 		4 SER A 187
VAL A 119
TYR A 121
ASP A 189
 None
 1.17A 2x45B-3nqhA:
undetectable		 2x45B-3nqhA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p02 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14274
(DUF4361)
PF16343
(DUF4973) 		4 SER A 302
TYR A 231
TYR A 225
ASP A 299
 EDO  A   3 ( 4.3A)
None
None
EDO  A   3 ( 4.9A)
 1.22A 2x45B-3p02A:
1.4		 2x45B-3p02A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8k HYDROLASE,
CARBON-NITROGEN
FAMILY

(Staphylococcus
aureus) 		PF00795
(CN_hydrolase) 		4 SER A 136
VAL A 141
ILE A 105
ASP A  77
 CL  A 269 (-4.8A)
None
None
CL  A 269 (-3.7A)
 1.24A 2x45B-3p8kA:
undetectable		 2x45B-3p8kA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdf DIPEPTIDYL PEPTIDASE
1

(Homo sapiens) 		PF00112
(Peptidase_C1)
PF08773
(CathepsinC_exc) 		4 TYR A 321
VAL A 431
TYR A 323
ILE A  63
 None
None
CL  A 443 (-4.7A)
None
 1.13A 2x45B-3pdfA:
3.8		 2x45B-3pdfA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qc5 PLATELET BINDING
PROTEIN GSPB

(Streptococcus
gordonii) 		no annotation 4 TYR X 256
VAL X 254
TYR X 391
ILE X 264
 None
 1.06A 2x45B-3qc5X:
undetectable		 2x45B-3qc5X:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qz4 ENDO-1,4-BETA-XYLANA
SE D

(Bacteroides
thetaiotaomicron) 		PF04616
(Glyco_hydro_43) 		4 TYR A 229
VAL A 222
TYR A 178
ASP A 169
 None
 1.19A 2x45B-3qz4A:
undetectable		 2x45B-3qz4A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4q LACTOYLGLUTATHIONE
LYASE

(Agrobacterium
fabrum) 		PF00903
(Glyoxalase) 		4 TYR A  26
VAL A  29
ILE A 119
ASP A 121
 None
 1.17A 2x45B-3r4qA:
undetectable		 2x45B-3r4qA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sxf CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Toxoplasma
gondii) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 SER A 199
VAL A 222
TYR A 227
ASP A 174
 None
 1.08A 2x45B-3sxfA:
undetectable		 2x45B-3sxfA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgx CHROMOSOME PARTITION
PROTEIN SMC

(Bacillus
subtilis) 		PF02463
(SMC_N) 		4 SER A 152
VAL A1072
ILE A 149
ASP A 156
 None
 1.07A 2x45B-3zgxA:
undetectable		 2x45B-3zgxA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 SER A 546
TYR A 260
ILE A 255
ASP A  81
 None
 1.22A 2x45B-3zs6A:
undetectable		 2x45B-3zs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 SER A 546
TYR A 280
VAL A 532
ILE A 255
 None
 1.12A 2x45B-3zs6A:
undetectable		 2x45B-3zs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dbe OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Sulfolobus
solfataricus) 		PF00215
(OMPdecase) 		4 TYR A 183
VAL A 162
TYR A 109
ILE A  57
 None
 1.11A 2x45B-4dbeA:
undetectable		 2x45B-4dbeA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dia 2-PYRONE-4,6-DICARBA
XYLATE HYDROLASE

(Sphingomonas
paucimobilis) 		PF04909
(Amidohydro_2) 		4 VAL A  72
TYR A 290
ILE A 244
ASP A 179
 None
 1.22A 2x45B-4diaA:
undetectable		 2x45B-4diaA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF14725
(DUF4466) 		4 SER A 170
TYR A 331
ILE A  52
ASP A 277
 None
None
GOL  A 400 (-4.7A)
None
 1.19A 2x45B-4ei0A:
undetectable		 2x45B-4ei0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzh HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.14A 2x45B-4fzhA:
undetectable		 2x45B-4fzhA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hf7 PUTATIVE
ACYLHYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13472
(Lipase_GDSL_2) 		4 SER A  90
VAL A 153
ILE A 134
ASP A 117
 None
 1.02A 2x45B-4hf7A:
undetectable		 2x45B-4hf7A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyj GDSL-LIKE PROTEIN

(Bacteroides
uniformis) 		PF13472
(Lipase_GDSL_2) 		4 SER A  82
VAL A 145
ILE A 126
ASP A 109
 None
 1.08A 2x45B-4iyjA:
undetectable		 2x45B-4iyjA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE

(Leishmania
major) 		PF00348
(polyprenyl_synt) 		4 SER A 173
TYR A 195
VAL A 279
ILE A 203
 None
 1.26A 2x45B-4jzxA:
undetectable		 2x45B-4jzxA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n30 PROTEIN DISULFIDE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF13462
(Thioredoxin_4) 		4 SER A 177
VAL A 187
TYR A  61
ILE A 174
 None
 1.07A 2x45B-4n30A:
undetectable		 2x45B-4n30A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4on1 PUTATIVE
METALLOPROTEASE II

(Bacteroides
fragilis) 		PF00413
(Peptidase_M10)
PF16376
(fragilysinNterm) 		4 SER A 247
VAL A 259
TYR A 261
ILE A 353
 None
 1.11A 2x45B-4on1A:
undetectable		 2x45B-4on1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovk PERIPLASMIC BINDING
PROTEIN

(Veillonella
parvula) 		PF01497
(Peripla_BP_2) 		4 SER A  94
TYR A 339
ILE A 300
TRP A 303
 None
 1.15A 2x45B-4ovkA:
undetectable		 2x45B-4ovkA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p27 VENOM ALLERGEN-LIKE
(VAL) 4 PROTEIN

(Schistosoma
mansoni) 		PF00188
(CAP) 		4 TYR A  81
TYR A  58
ASP A  90
TRP A  91
 None
 1.26A 2x45B-4p27A:
undetectable		 2x45B-4p27A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p8b TRAP-TYPE
TRANSPORTER,
PERIPLASMIC
COMPONENT

(Cupriavidus
necator) 		PF03480
(DctP) 		4 SER A  36
VAL A 247
ILE A  91
TRP A 101
 None
 1.05A 2x45B-4p8bA:
undetectable		 2x45B-4p8bA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qqs GLYCOSIDE HYDROLASE
FAMILY 43

(Halothermothrix
orenii) 		PF04616
(Glyco_hydro_43) 		4 TYR A 206
VAL A 199
TYR A 140
ASP A 132
 None
 1.10A 2x45B-4qqsA:
undetectable		 2x45B-4qqsA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qti UROKINASE
PLASMINOGEN
ACTIVATOR SURFACE
RECEPTOR

(Homo sapiens) 		PF00021
(UPAR_LY6) 		4 VAL U 238
TYR U 236
ILE U 130
ASP U 163
 None
 1.05A 2x45B-4qtiU:
undetectable		 2x45B-4qtiU:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgj CALCIUM-DEPENDENT
PROTEIN KINASE 4

(Plasmodium
falciparum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 SER A 417
VAL A 100
TYR A 144
ASP A 420
 None
 0.91A 2x45B-4rgjA:
undetectable		 2x45B-4rgjA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tu3 PHOSPHOINOSITIDE
PHOSPHATASE SAC1

(Saccharomyces
cerevisiae) 		PF02383
(Syja_N) 		4 SER X  94
VAL X  53
TYR X   7
ILE X  72
 None
 1.25A 2x45B-4tu3X:
undetectable		 2x45B-4tu3X:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wtv PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-BETA,ENDOLYSIN,PHO
SPHATIDYLINOSITOL
4-KINASE TYPE 2-BETA

(Escherichia
virus T4;
Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF00959
(Phage_lysozyme) 		4 SER A 214
TYR A 134
VAL A 136
ILE A 117
 None
 1.26A 2x45B-4wtvA:
undetectable		 2x45B-4wtvA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xf5 TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL

(Chromohalobacter
salexigens) 		PF03480
(DctP) 		4 SER A 216
VAL A 224
ILE A 213
TRP A 198
 None
 1.14A 2x45B-4xf5A:
undetectable		 2x45B-4xf5A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1g UNCHARACTERIZED
PROTEIN SAV1875

(Staphylococcus
aureus) 		PF01965
(DJ-1_PfpI) 		4 VAL A  51
TYR A  18
ILE A   7
ASP A  54
 None
 1.00A 2x45B-4y1gA:
undetectable		 2x45B-4y1gA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfa PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		4 SER C 392
VAL C 345
TYR C 481
ASP C 385
 None
 1.24A 2x45B-4yfaC:
undetectable		 2x45B-4yfaC:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv7 LIPASE B

(Moesziomyces
antarcticus) 		no annotation 4 SER A 105
VAL A 154
ILE A 189
ASP A 134
 None
 1.22A 2x45B-4zv7A:
undetectable		 2x45B-4zv7A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxl O-GLCNACASE NAGJ

(Clostridium
perfringens) 		PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase) 		4 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.10A 2x45B-4zxlA:
undetectable		 2x45B-4zxlA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		4 SER A1342
VAL A1738
TYR A1596
ILE A1730
 None
 1.15A 2x45B-5amqA:
undetectable		 2x45B-5amqA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 SER A  78
TYR A 408
ILE A  73
ASP A 105
 None
0HK  A 501 (-4.7A)
None
0HK  A 501 (-3.0A)
 1.22A 2x45B-5cxvA:
undetectable		 2x45B-5cxvA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 SER A  85
TYR A 439
ILE A  81
ASP A 112
 None
0HK  A1201 (-3.6A)
None
0HK  A1201 (-4.0A)
 1.26A 2x45B-5dsgA:
undetectable		 2x45B-5dsgA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA

(Bacillus
thuringiensis) 		no annotation 4 TYR A 130
VAL A 119
TYR A 115
ILE A 339
 None
 1.13A 2x45B-5gheA:
undetectable		 2x45B-5gheA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5izd D-GLYCERALDEHYDE
DEHYDROGENASE
(NADP(+))

(Thermoplasma
acidophilum) 		PF00171
(Aldedh) 		4 VAL A 395
TYR A 399
ASP A 417
TRP A 257
 None
 0.96A 2x45B-5izdA:
undetectable		 2x45B-5izdA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j68 ASTROTACTIN-2

(Homo sapiens) 		PF01823
(MACPF) 		4 SER A1203
TYR A1189
VAL A1185
ILE A1215
 None
 1.05A 2x45B-5j68A:
undetectable		 2x45B-5j68A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j8j HISTONE DEACETYLASE
HDA1

(Saccharomyces
cerevisiae) 		PF09757
(Arb2) 		4 SER A 646
VAL A 603
TYR A 599
ILE A 648
 None
 0.61A 2x45B-5j8jA:
undetectable		 2x45B-5j8jA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kuc PESTICIDAL CRYSTAL
PROTEIN CRY6AA

(Bacillus
thuringiensis) 		no annotation 4 TYR A 130
VAL A 119
TYR A 115
ILE A 339
 None
 1.17A 2x45B-5kucA:
undetectable		 2x45B-5kucA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m7r PROTEIN O-GLCNACASE

(Homo sapiens) 		PF07555
(NAGidase) 		4 SER A 268
VAL A 228
ILE A 271
TRP A 249
 None
 1.19A 2x45B-5m7rA:
undetectable		 2x45B-5m7rA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2d PROGRAMMED CELL
DEATH 1 LIGAND 1

(Homo sapiens) 		PF07686
(V-set) 		4 TYR A  28
VAL A 128
TYR A 112
ILE A 101
 None
 1.22A 2x45B-5n2dA:
undetectable		 2x45B-5n2dA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n72 WIPA

(Legionella
pneumophila) 		no annotation 4 TYR A 384
VAL A 389
ILE A 298
ASP A 311
 None
 0.99A 2x45B-5n72A:
undetectable		 2x45B-5n72A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol2 ACYL-COA
DEHYDROGENASE

(Clostridioides
difficile) 		no annotation 4 TYR C   8
TYR C  15
ILE C  52
ASP C  64
 None
 1.21A 2x45B-5ol2C:
undetectable		 2x45B-5ol2C:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sym ACYL-PROTEIN
THIOESTERASE 1

(Homo sapiens) 		PF02230
(Abhydrolase_2) 		4 VAL A  24
TYR A  51
ILE A  44
ASP A 223
 None
 1.17A 2x45B-5symA:
undetectable		 2x45B-5symA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u5g 6-PHOSPHOGLUCONATE
DEHYDROGENASE

(Pseudomonas
syringae) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 SER A 231
TYR A 224
VAL A 220
ASP A 278
 None
 1.22A 2x45B-5u5gA:
undetectable		 2x45B-5u5gA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vvo PROTEIN O-GLCNACASE

(Homo sapiens) 		PF07555
(NAGidase) 		4 SER A 268
VAL A 228
ILE A 271
TRP A 249
 None
 1.19A 2x45B-5vvoA:
undetectable		 2x45B-5vvoA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cl5 TAIL FIBER PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 4 SER A 461
VAL A 492
ILE A 459
TRP A 468
 None
 1.24A 2x45B-6cl5A:
undetectable		 2x45B-6cl5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE

(Staphylococcus
aureus) 		no annotation 4 TYR A  83
VAL A  80
TYR A  90
ILE A  38
 None
 0.96A 2x45B-6fdgA:
undetectable		 2x45B-6fdgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gu8 -

(-) 		no annotation 4 SER A 289
VAL A  68
TYR A 312
ASP A 325
 None
 1.25A 2x45B-6gu8A:
undetectable		 2x45B-6gu8A:
undetectable