SIMILAR PATTERNS OF AMINO ACIDS FOR 2WLJ_A_SPMA1303
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 3 | ARG A 20ARG A 415PRO A 416 | None | 1.05A | 2wljA-1a3xA:0.0 | 2wljA-1a3xA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 3 | ARG A 431ARG A 428PRO A 427 | None | 1.01A | 2wljA-1a3xA:0.0 | 2wljA-1a3xA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b4p | PROTEIN (GLUTATHIONES-TRANSFERASE) (Rattusnorvegicus) |
PF00043(GST_C)PF02798(GST_N) | 3 | ARG A 107ARG A 10PRO A 15 | None | 0.87A | 2wljA-1b4pA:0.0 | 2wljA-1b4pA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 3 | ARG A 181ARG A 127PRO A 121 | None | 0.94A | 2wljA-1ciyA:0.3 | 2wljA-1ciyA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f3b | GLUTATHIONES-TRANSFERASE YACHAIN (Mus musculus) |
PF00043(GST_C)PF02798(GST_N) | 3 | ARG A 12ARG A 19PRO A 205 | None | 1.11A | 2wljA-1f3bA:3.0 | 2wljA-1f3bA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f5a | POLY(A) POLYMERASE (Bos taurus) |
PF01909(NTP_transf_2)PF04926(PAP_RNA-bind)PF04928(PAP_central) | 3 | ARG A 196ARG A 199PRO A 155 | None | 1.08A | 2wljA-1f5aA:0.0 | 2wljA-1f5aA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g70 | RSG-1.2 PEPTIDE (Humanimmunodeficiencyvirus 1) |
no annotation | 3 | ARG B 17ARG B 14PRO B 9 | U A 66 ( 2.7A) G A 70 ( 3.2A) U A 66 ( 3.9A) | 0.99A | 2wljA-1g70B:undetectable | 2wljA-1g70B:6.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ikp | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 3 | ARG A 392ARG A 563PRO A 559 | None | 0.84A | 2wljA-1ikpA:2.5 | 2wljA-1ikpA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3b | ATP-DEPENDENTPHOSPHOENOLPYRUVATECARBOXYKINASE (Thermusthermophilus) |
PF01293(PEPCK_ATP) | 3 | ARG A 340ARG A 420PRO A 419 | PO4 A2004 (-2.4A)NoneNone | 1.08A | 2wljA-1j3bA:undetectable | 2wljA-1j3bA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7y | METHIONINE SYNTHASE (Escherichiacoli) |
PF02310(B12-binding)PF02607(B12-binding_2)PF02965(Met_synt_B12) | 3 | ARG A 896ARG A 900PRO A 899 | None | 1.09A | 2wljA-1k7yA:2.5 | 2wljA-1k7yA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kn6 | PROHORMONECONVERTASE 1 (Mus musculus) |
PF16470(S8_pro-domain) | 3 | ARG A 51ARG A 50PRO A 49 | None | 1.02A | 2wljA-1kn6A:undetectable | 2wljA-1kn6A:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lsh | LIPOVITELLIN (LV-2) (Ichthyomyzonunicuspis) |
PF09175(DUF1944) | 3 | ARG B1505ARG B1506PRO B1504 | None | 0.98A | 2wljA-1lshB:undetectable | 2wljA-1lshB:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mty | METHANEMONOOXYGENASEHYDROXYLASE (Methylococcuscapsulatus) |
PF02332(Phenol_Hydrox) | 3 | ARG B 42ARG B 103PRO B 101 | None | 0.88A | 2wljA-1mtyB:2.1 | 2wljA-1mtyB:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1opg | OPG2 FAB (HEAVYCHAIN) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | ARG H 200ARG H 225PRO H 138 | None | 1.08A | 2wljA-1opgH:3.4 | 2wljA-1opgH:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qm9 | POLYPYRIMIDINETRACT-BINDINGPROTEIN (Homo sapiens) |
PF00076(RRM_1)PF13893(RRM_5) | 3 | ARG A 158ARG A 72PRO A 70 | None | 0.84A | 2wljA-1qm9A:undetectable | 2wljA-1qm9A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u3d | CRYPTOCHROME 1APOPROTEIN (Arabidopsisthaliana) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 3 | ARG A 313ARG A 378PRO A 314 | None | 1.09A | 2wljA-1u3dA:undetectable | 2wljA-1u3dA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uaa | PROTEIN(ATP-DEPENDENT DNAHELICASE REP.) (Escherichiacoli) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 3 | ARG A 501ARG A 380PRO A 381 | None | 1.00A | 2wljA-1uaaA:undetectable | 2wljA-1uaaA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vf1 | GLUTATHIONES-TRANSFERASE 3 (Gallus gallus) |
PF02798(GST_N)PF14497(GST_C_3) | 3 | ARG A 13ARG A 20PRO A 206 | None | 1.08A | 2wljA-1vf1A:undetectable | 2wljA-1vf1A:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wg6 | HYPOTHETICAL PROTEIN(RIKEN CDNA2810455B10) (Mus musculus) |
PF00595(PDZ) | 3 | ARG A 120ARG A 121PRO A 124 | None | 1.03A | 2wljA-1wg6A:undetectable | 2wljA-1wg6A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wlk | FMN-BINDING PROTEIN (Desulfovibriovulgaris) |
PF01243(Putative_PNPOx) | 3 | ARG A 43ARG A 92PRO A 96 | None | 1.09A | 2wljA-1wlkA:undetectable | 2wljA-1wlkA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbo | HYPOTHETICAL PROTEINBPP1347 (Bordetellaparapertussis) |
PF02190(LON_substr_bdg) | 3 | ARG A 155ARG A 165PRO A 153 | None | 0.96A | 2wljA-1zboA:undetectable | 2wljA-1zboA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zq1 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT E (Pyrococcusabyssi) |
PF02637(GatB_Yqey)PF02934(GatB_N)PF02938(GAD) | 3 | ARG C 340ARG C 412PRO C 408 | None | 0.89A | 2wljA-1zq1C:undetectable | 2wljA-1zq1C:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb1 | O-ACETYL HOMOSERINESULFHYDRYLASE (Thermusthermophilus) |
PF01053(Cys_Met_Meta_PP) | 3 | ARG A 93ARG A 142PRO A 227 | None | 1.04A | 2wljA-2cb1A:undetectable | 2wljA-2cb1A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cja | SERYL-TRNASYNTHETASE (Methanosarcinabarkeri) |
no annotation | 3 | ARG A 143ARG A 147PRO A 145 | None | 0.74A | 2wljA-2cjaA:undetectable | 2wljA-2cjaA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dnm | SRP46 SPLICINGFACTOR (Homo sapiens) |
PF00076(RRM_1) | 3 | ARG A 47ARG A 55PRO A 54 | None | 1.11A | 2wljA-2dnmA:undetectable | 2wljA-2dnmA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e0w | GAMMA-GLUTAMYLTRANSPEPTIDASE (Escherichiacoli) |
PF01019(G_glu_transpept) | 3 | ARG A 114ARG A 459PRO A 460 | None | 1.01A | 2wljA-2e0wA:undetectable | 2wljA-2e0wA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eke | UBIQUITIN-LIKEPROTEIN SMT3 (Saccharomycescerevisiae) |
PF11976(Rad60-SLD) | 3 | ARG C1046ARG C1047PRO C1044 | None | 1.01A | 2wljA-2ekeC:undetectable | 2wljA-2ekeC:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gtl | EXTRACELLULARHEMOGLOBIN LINKER L2SUBUNITEXTRACELLULARHEMOGLOBIN LINKER L3SUBUNIT (Lumbricusterrestris) |
PF00057(Ldl_recept_a)PF16915(Eryth_link_C) | 3 | ARG O 38ARG O 43PRO N 43 | None | 0.85A | 2wljA-2gtlO:undetectable | 2wljA-2gtlO:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iny | HEXON PROTEIN (Fowlaviadenovirus A) |
PF01065(Adeno_hexon)PF03678(Adeno_hexon_C) | 3 | ARG A 923ARG A 604PRO A 545 | None | 1.11A | 2wljA-2inyA:undetectable | 2wljA-2inyA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ood | BLR3880 PROTEIN (Bradyrhizobiumdiazoefficiens) |
PF01979(Amidohydro_1) | 3 | ARG A 369ARG A 318PRO A 315 | None | 0.99A | 2wljA-2oodA:undetectable | 2wljA-2oodA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v1n | PROTEIN KIN HOMOLOG (Homo sapiens) |
PF10357(Kin17_mid) | 3 | ARG A 101ARG A 102PRO A 97 | None | 0.97A | 2wljA-2v1nA:undetectable | 2wljA-2v1nA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 3 | ARG A 728ARG A 708PRO A 707 | None | 0.94A | 2wljA-2vz9A:undetectable | 2wljA-2vz9A:7.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3t | CYTOCHROME P450 (Streptomycessp. TP-A0274) |
PF00067(p450) | 3 | ARG A 145ARG A 144PRO A 146 | None | 1.12A | 2wljA-2z3tA:undetectable | 2wljA-2z3tA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cob | KINESIN HEAVYCHAIN-LIKE PROTEIN (Solanumtuberosum) |
PF00225(Kinesin) | 3 | ARG A 897ARG A 895PRO A 898 | NoneADP A 600 (-4.0A)ADP A 600 (-4.7A) | 1.12A | 2wljA-3cobA:undetectable | 2wljA-3cobA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dlv | SIGNAL RECOGNITIONPARTICLE 19 KDAPROTEIN (Pyrococcusfuriosus) |
no annotation | 3 | ARG B 17ARG B 25PRO B 24 | None | 1.03A | 2wljA-3dlvB:undetectable | 2wljA-3dlvB:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3edl | KINESIN13 MOTORDOMAIN (Drosophilamelanogaster) |
PF00225(Kinesin) | 3 | ARG D 80ARG D 78PRO D 81 | NoneANP D 500 ( 3.7A)ANP D 500 ( 4.7A) | 1.05A | 2wljA-3edlD:undetectable | 2wljA-3edlD:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gm8 | GLYCOSIDE HYDROLASEFAMILY 2, CANDIDATEBETA-GLYCOSIDASE (Bacteroidesvulgatus) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 3 | ARG A 188ARG A 399PRO A 433 | None | 1.04A | 2wljA-3gm8A:4.1 | 2wljA-3gm8A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i32 | HEAT RESISTANT RNADEPENDENT ATPASE (Thermusthermophilus) |
PF00271(Helicase_C) | 3 | ARG A 444ARG A 449PRO A 443 | None | 1.12A | 2wljA-3i32A:undetectable | 2wljA-3i32A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3izq | ELONGATION FACTOR 1ALPHA-LIKE PROTEIN (Saccharomycescerevisiae) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF08938(HBS1_N) | 3 | ARG 1 540ARG 1 537PRO 1 521 | None | 0.92A | 2wljA-3izq1:undetectable | 2wljA-3izq1:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2u | KINESIN-LIKE PROTEINKLP10A (Drosophilamelanogaster) |
PF00225(Kinesin) | 3 | ARG K 286ARG K 284PRO K 287 | None | 1.04A | 2wljA-3j2uK:undetectable | 2wljA-3j2uK:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j70 | ENVELOPEGLYCOPROTEIN GP120 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 3 | ARG D 311ARG D 308PRO D 313 | None | 0.76A | 2wljA-3j70D:undetectable | 2wljA-3j70D:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n4p | TERMINASE SUBUNITUL89 PROTEIN (Humanbetaherpesvirus5) |
PF02499(DNA_pack_C) | 3 | ARG A 670ARG A 672PRO A 567 | None | 1.12A | 2wljA-3n4pA:undetectable | 2wljA-3n4pA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oa0 | LIPOPOLYSACCHARIDEBIOSYNTHESIS PROTEINWBPB (Thermusthermophilus) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 3 | ARG A 305ARG A 222PRO A 302 | None | 0.93A | 2wljA-3oa0A:undetectable | 2wljA-3oa0A:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olq | UNIVERSAL STRESSPROTEIN E (Proteusmirabilis) |
PF00582(Usp) | 3 | ARG A 22ARG A 23PRO A 19 | UNL A 321 ( 3.4A)UNL A 321 ( 4.6A)None | 1.08A | 2wljA-3olqA:undetectable | 2wljA-3olqA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9b | VIPERA RUSSELLIPROTEINASE RVV-VGAMMA (Daboiasiamensis) |
PF00089(Trypsin) | 3 | ARG A 110ARG A 86PRO A 111 | None | 0.85A | 2wljA-3s9bA:undetectable | 2wljA-3s9bA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t0q | AGR253WP (Eremotheciumgossypii) |
PF00225(Kinesin) | 3 | ARG A 374ARG A 372PRO A 375 | ADP A 999 (-4.6A)ADP A 999 (-3.2A)ADP A 999 (-4.4A) | 1.11A | 2wljA-3t0qA:1.3 | 2wljA-3t0qA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdw | GENTAMICINRESISTANCE PROTEIN (Enterococcusgallinarum) |
PF01636(APH) | 3 | ARG A 115ARG A 209PRO A 212 | None | 1.11A | 2wljA-3tdwA:undetectable | 2wljA-3tdwA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqs | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE A (Coxiellaburnetii) |
PF00398(RrnaAD) | 3 | ARG A 214ARG A 241PRO A 242 | None | 0.93A | 2wljA-3tqsA:undetectable | 2wljA-3tqsA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tts | BETA-GALACTOSIDASE (Bacilluscirculans) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 3 | ARG A 394ARG A 295PRO A 302 | None | 1.13A | 2wljA-3ttsA:undetectable | 2wljA-3ttsA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wme | ATP-BINDINGCASSETTE, SUB-FAMILYB, MEMBER 1 (Cyanidioschyzonmerolae) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 3 | ARG A 424ARG A 493PRO A 511 | None | 1.06A | 2wljA-3wmeA:4.0 | 2wljA-3wmeA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdb | PROTEIN XNI (Escherichiacoli) |
PF01367(5_3_exonuc)PF02739(5_3_exonuc_N) | 3 | ARG A 15ARG A 70PRO A 71 | None | 1.01A | 2wljA-3zdbA:undetectable | 2wljA-3zdbA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zj0 | ACETYLTRANSFERASE (Oceanicolagranulosus) |
PF00583(Acetyltransf_1) | 3 | ARG A 93ARG A 118PRO A 119 | None | 1.11A | 2wljA-3zj0A:undetectable | 2wljA-3zj0A:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ab4 | XENOBIOTIC REDUCTASEB (Pseudomonasputida) |
PF00724(Oxidored_FMN) | 3 | ARG A 348ARG A 320PRO A 315 | None | 1.13A | 2wljA-4ab4A:undetectable | 2wljA-4ab4A:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ad8 | DNA REPAIR PROTEINRECN (Deinococcusradiodurans) |
PF02463(SMC_N) | 3 | ARG A 496ARG A 33PRO A 32 | None | 0.97A | 2wljA-4ad8A:3.0 | 2wljA-4ad8A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ap5 | GDP-FUCOSE PROTEINO-FUCOSYLTRANSFERASE2 (Homo sapiens) |
PF10250(O-FucT) | 3 | ARG A 295ARG A 303PRO A 307 | None | 1.06A | 2wljA-4ap5A:undetectable | 2wljA-4ap5A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4awl | NUCLEARTRANSCRIPTION FACTORY SUBUNIT ALPHA (Homo sapiens) |
PF02045(CBFB_NFYA) | 3 | ARG A 267ARG A 266PRO A 263 | None | 0.75A | 2wljA-4awlA:undetectable | 2wljA-4awlA:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4h | GLUTAMINE DEPENDENTNAD+ SYNTHETASE (Burkholderiathailandensis) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 3 | ARG A 501ARG A 57PRO A 58 | None | 1.14A | 2wljA-4f4hA:undetectable | 2wljA-4f4hA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fc8 | TRANSCRIPTIONPROTEIN RTR1 (Kluyveromyceslactis) |
PF04181(RPAP2_Rtr1) | 3 | ARG A 53ARG A 134PRO A 144 | None | 1.01A | 2wljA-4fc8A:undetectable | 2wljA-4fc8A:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfj | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 3 | ARG A 231ARG A 436PRO A 220 | None | 0.98A | 2wljA-4gfjA:2.9 | 2wljA-4gfjA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homo sapiens) |
PF00043(GST_C)PF02798(GST_N) | 3 | ARG A 13ARG A 20PRO A 206 | None | 1.09A | 2wljA-4hj2A:undetectable | 2wljA-4hj2A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4inq | OXYSTEROL-BINDINGPROTEIN HOMOLOG 3 (Saccharomycescerevisiae) |
PF01237(Oxysterol_BP) | 3 | ARG A 713ARG A 716PRO A 667 | None | 0.99A | 2wljA-4inqA:undetectable | 2wljA-4inqA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jed | GLUTATHIONES-TRANSFERASE (Methylobacteriumradiotolerans) |
PF13410(GST_C_2)PF13417(GST_N_3) | 3 | ARG A 116ARG A 174PRO A 176 | NoneNoneGOL A 301 (-4.5A) | 1.06A | 2wljA-4jedA:undetectable | 2wljA-4jedA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kbm | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Mycobacteriumtuberculosis) |
PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1) | 3 | ARG A 392ARG A 276PRO A 277 | None | 1.05A | 2wljA-4kbmA:undetectable | 2wljA-4kbmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kng | E3 UBIQUITIN-PROTEINLIGASE RNF43 (Homo sapiens) |
no annotation | 3 | ARG E 113ARG E 114PRO E 112 | None | 0.89A | 2wljA-4kngE:undetectable | 2wljA-4kngE:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ljp | E3 UBIQUITIN-PROTEINLIGASE RNF31 (Homo sapiens) |
no annotation | 3 | ARG A 928ARG A1032PRO A 927 | None | 1.03A | 2wljA-4ljpA:undetectable | 2wljA-4ljpA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m3o | KLLA0F12672P (Kluyveromyceslactis) |
PF04181(RPAP2_Rtr1) | 3 | ARG A 53ARG A 134PRO A 144 | None | 0.98A | 2wljA-4m3oA:undetectable | 2wljA-4m3oA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n4r | LPS-ASSEMBLYLIPOPROTEIN LPTELPS-ASSEMBLY PROTEINLPTD (Salmonellaenterica) |
PF04390(LptE)PF04453(OstA_C) | 3 | ARG A 326ARG B 49PRO B 46 | None | 1.10A | 2wljA-4n4rA:undetectable | 2wljA-4n4rA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqj | PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 3 | ARG A 505ARG A 124PRO A 122 | None | 1.08A | 2wljA-4oqjA:undetectable | 2wljA-4oqjA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qn9 | N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D (Homo sapiens) |
PF12706(Lactamase_B_2) | 3 | ARG A 164ARG A 167PRO A 169 | NoneSO4 A 508 (-2.6A)None | 1.11A | 2wljA-4qn9A:undetectable | 2wljA-4qn9A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ras | OXIDOREDUCTASE,NAD-BINDING/IRON-SULFUR CLUSTER-BINDINGPROTEIN (Nitratireductorpacificus) |
PF12838(Fer4_7)PF13486(Dehalogenase) | 3 | ARG A 9ARG A 2PRO A 15 | None | 1.13A | 2wljA-4rasA:0.7 | 2wljA-4rasA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rul | DNA TOPOISOMERASE 1 (Escherichiacoli) |
PF01131(Topoisom_bac)PF01396(zf-C4_Topoisom)PF01751(Toprim)PF08272(Topo_Zn_Ribbon) | 3 | ARG A 207ARG A 476PRO A 474 | None | 1.10A | 2wljA-4rulA:undetectable | 2wljA-4rulA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ug4 | CHOLINE SULFATASE (Sinorhizobiummeliloti) |
PF00884(Sulfatase)PF12411(Choline_sulf_C) | 3 | ARG A 510ARG A 507PRO A 509 | None | 1.05A | 2wljA-4ug4A:undetectable | 2wljA-4ug4A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4us7 | PILD PROCESSEDPROTEIN (Shewanellaoneidensis) |
PF16732(ComP_DUS) | 3 | ARG A 64ARG A 5PRO A 40 | None | 1.09A | 2wljA-4us7A:undetectable | 2wljA-4us7A:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wqe | THIOSULFATEDEHYDROGENASE (Allochromatiumvinosum) |
PF13442(Cytochrome_CBB3) | 3 | ARG A 177ARG A 50PRO A 36 | None | 1.11A | 2wljA-4wqeA:undetectable | 2wljA-4wqeA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dxi | TREHALOSE-6-PHOSPHATE PHOSPHATASE (Candidaalbicans) |
PF02358(Trehalose_PPase) | 3 | ARG A 143ARG A 142PRO A 37 | NoneTRE A 403 (-3.8A)TRE A 403 (-4.0A) | 1.07A | 2wljA-5dxiA:3.1 | 2wljA-5dxiA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dzt | CYLM (Enterococcusfaecalis) |
PF05147(LANC_like)PF13575(DUF4135) | 3 | ARG A 514ARG A 510PRO A 511 | None | 1.05A | 2wljA-5dztA:1.9 | 2wljA-5dztA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fkc | BETA-FRUCTOFURANOSIDASE (Xanthophyllomycesdendrorhous) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 3 | ARG A 387ARG A 459PRO A 462 | None | 0.96A | 2wljA-5fkcA:undetectable | 2wljA-5fkcA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hm5 | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 3 | ARG A 231ARG A 436PRO A 220 | None | 1.12A | 2wljA-5hm5A:2.1 | 2wljA-5hm5A:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ic7 | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
no annotation | 3 | ARG A 497ARG A 481PRO A 474 | NoneSO4 A 704 (-4.0A)None | 1.11A | 2wljA-5ic7A:undetectable | 2wljA-5ic7A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip4 | NEURONAL MIGRATIONPROTEIN DOUBLECORTIN (Homo sapiens) |
PF03607(DCX) | 3 | ARG D 267ARG D 273PRO D 272 | None | 1.06A | 2wljA-5ip4D:undetectable | 2wljA-5ip4D:14.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jzb | 4,5:9,10-DISECO-3-HYDROXY-5,9,17-TRIOXOANDROSTA-1(10),2-DIENE-4-OATE HYDROLASE (Mycobacteriumtuberculosis) |
PF12697(Abhydrolase_6) | 3 | ARG A 228ARG A 230PRO A 128 | None | 1.04A | 2wljA-5jzbA:undetectable | 2wljA-5jzbA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw7 | ABC TRANSPORTERATP-BINDING PROTEIN (Pyrococcusabyssi) |
PF00005(ABC_tran)PF00037(Fer4)PF04068(RLI) | 3 | ARG B 304ARG B 570PRO B 566 | None | 0.99A | 2wljA-5lw7B:undetectable | 2wljA-5lw7B:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw7 | ABC TRANSPORTERATP-BINDING PROTEIN (Pyrococcusabyssi) |
PF00005(ABC_tran)PF00037(Fer4)PF04068(RLI) | 3 | ARG B 304ARG B 572PRO B 566 | None | 1.00A | 2wljA-5lw7B:undetectable | 2wljA-5lw7B:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mfa | MYELOPEROXIDASE (Homo sapiens) |
PF03098(An_peroxidase) | 3 | ARG A 529ARG A 536PRO A 526 | None | 1.06A | 2wljA-5mfaA:undetectable | 2wljA-5mfaA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqm | GLYCOSYL HYDROLASESFAMILY 2, SUGARBINDING DOMAIN (Bacteroidesthetaiotaomicron) |
PF17132(Glyco_hydro_106) | 3 | ARG A 714ARG A 753PRO A 751 | None | 1.03A | 2wljA-5mqmA:undetectable | 2wljA-5mqmA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oq3 | CWP19 (Clostridioidesdifficile) |
no annotation | 3 | ARG A 132ARG A 79PRO A 80 | None | 0.99A | 2wljA-5oq3A:undetectable | 2wljA-5oq3A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ovy | PUTATIVETRANSCRIPTIONALREGULATOR, TETRFAMILY (Mycobacteroidesabscessus) |
no annotation | 3 | ARG B 197ARG B 148PRO B 149 | None | 1.01A | 2wljA-5ovyB:undetectable | 2wljA-5ovyB:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t06 | ACYL-COA THIOESTERHYDROLASE YBGC (Escherichiacoli) |
PF03061(4HBT) | 3 | ARG A 54ARG A 122PRO A 116 | None | 1.06A | 2wljA-5t06A:undetectable | 2wljA-5t06A:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u30 | CRISPR-ASSOCIATEDENDONUCLEASE C2C1 (Alicyclobacillusacidoterrestris) |
no annotation | 3 | ARG A 50ARG A 51PRO A 53 | None | 0.91A | 2wljA-5u30A:3.5 | 2wljA-5u30A:15.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj7 | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF00004(AAA)PF09079(Cdc6_C) | 3 | ARG A 720ARG A 721PRO A 536 | ATP A 900 (-3.9A)NoneATP A 900 (-4.0A) | 1.00A | 2wljA-5uj7A:undetectable | 2wljA-5uj7A:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujm | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF00004(AAA)PF09079(Cdc6_C) | 3 | ARG A 720ARG A 721PRO A 536 | ATP A 901 (-3.9A)NoneATP A 901 (-4.0A) | 1.00A | 2wljA-5ujmA:undetectable | 2wljA-5ujmA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wpk | 3-HYDROXY-3-METHYLGLUTARYL COENZYME AREDUCTASE (Streptococcuspneumoniae) |
no annotation | 3 | ARG A 30ARG A 334PRO A 333 | None | 1.01A | 2wljA-5wpkA:undetectable | 2wljA-5wpkA:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wq8 | TYPE II SECRETIONSYSTEM PROTEIN D (Vibrio cholerae) |
PF00263(Secretin)PF03958(Secretin_N) | 3 | ARG A 633ARG A 634PRO A 627 | None | 0.87A | 2wljA-5wq8A:undetectable | 2wljA-5wq8A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7u | TREHALOSE SYNTHASE (Thermobaculumterrenum) |
no annotation | 3 | ARG A 343ARG A 307PRO A 347 | None | 0.89A | 2wljA-5x7uA:undetectable | 2wljA-5x7uA:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y10 | MEMBRANEGLYCOPROTEINPOLYPROTEIN (SFTSphlebovirus) |
PF07243(Phlebovirus_G1) | 3 | ARG C 332ARG C 132PRO C 120 | None | 0.84A | 2wljA-5y10C:undetectable | 2wljA-5y10C:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | X-RAY REPAIRCROSS-COMPLEMENTINGPROTEIN 5 (Homo sapiens) |
PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 3 | ARG B 502ARG B 497PRO B 501 | None | 1.05A | 2wljA-5y3rB:undetectable | 2wljA-5y3rB:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykb | TREHALOSE SYNTHASE (Deinococcusradiodurans) |
no annotation | 3 | ARG A 352ARG A 316PRO A 356 | None | 0.86A | 2wljA-5ykbA:undetectable | 2wljA-5ykbA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f71 | GLUTATHIONETRANSFERASE (Trametesversicolor) |
no annotation | 3 | ARG A 174ARG A 20PRO A 18 | None | 1.07A | 2wljA-6f71A:undetectable | 2wljA-6f71A:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fbt | LYTIC MUREINTRANSGLYCOSYLASE (Pseudomonasaeruginosa) |
no annotation | 3 | ARG A 426ARG A 459PRO A 456 | None | 1.02A | 2wljA-6fbtA:undetectable | 2wljA-6fbtA:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gww | PEROXIREDOXIN (Sulfolobusislandicus) |
no annotation | 3 | ARG A 155ARG A 158PRO A 175 | None | 1.13A | 2wljA-6gwwA:undetectable | 2wljA-6gwwA:13.56 |