SIMILAR PATTERNS OF AMINO ACIDS FOR 2W98_B_P1ZB1359_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3y ODORANT BINDING
PROTEIN

(Sus scrofa) 		PF00061
(Lipocalin) 		4 GLU A  27
MET A 114
PHE A  35
ILE A  29
 None
 1.38A 2w98B-1a3yA:
undetectable		 2w98B-1a3yA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a4i METHYLENETETRAHYDROF
OLATE DEHYDROGENASE
/
METHENYLTETRAHYDROFO
LATE CYCLOHYDROLASE

(Homo sapiens) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 THR A 111
GLU A 112
MET A  82
ILE A 118
 None
 1.20A 2w98B-1a4iA:
7.7		 2w98B-1a4iA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1att ANTITHROMBIN III

(Bos taurus) 		PF00079
(Serpin) 		4 THR A 420
GLU A 415
PHE A 222
ILE A 220
 None
 1.22A 2w98B-1attA:
undetectable		 2w98B-1attA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1boo PROTEIN (N-4
CYTOSINE-SPECIFIC
METHYLTRANSFERASE
PVU II)

(Proteus
vulgaris) 		PF01555
(N6_N4_Mtase) 		4 THR A 278
MET A  51
PHE A 258
ILE A 259
 SAH  A 401 (-4.0A)
None
None
None
 1.35A 2w98B-1booA:
undetectable		 2w98B-1booA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgf CATALASE

(Homo sapiens) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 THR A 434
GLU A 191
MET A 350
ILE A 159
 None
None
HEM  A3000 (-3.7A)
None
 1.42A 2w98B-1dgfA:
undetectable		 2w98B-1dgfA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1di4 LYSOZYME C

(Homo sapiens) 		PF00062
(Lys) 		4 THR A  11
GLU A   7
MET A  29
ILE A  56
 None
 0.99A 2w98B-1di4A:
undetectable		 2w98B-1di4A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnf FIBRONECTIN

(Homo sapiens) 		PF00041
(fn3) 		4 THR A1301
GLU A1302
MET A1252
PHE A1244
 None
 1.41A 2w98B-1fnfA:
undetectable		 2w98B-1fnfA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jeo HYPOTHETICAL PROTEIN
MJ1247

(Methanocaldococcus
jannaschii) 		PF01380
(SIS) 		4 THR A  77
GLU A  74
PHE A  46
ILE A  45
 None
 1.30A 2w98B-1jeoA:
undetectable		 2w98B-1jeoA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nff PUTATIVE
OXIDOREDUCTASE
RV2002

(Mycobacterium
tuberculosis) 		PF13561
(adh_short_C2) 		4 THR A 164
GLU A 231
PHE A 232
ILE A 181
 None
 1.15A 2w98B-1nffA:
8.5		 2w98B-1nffA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvp TRANSCRIPTION
INITIATION FACTOR
IIA BETA CHAIN

(Homo sapiens) 		PF03153
(TFIIA) 		4 MET C 358
LYS C 369
PHE C 367
ILE C 366
 None
 1.41A 2w98B-1nvpC:
undetectable		 2w98B-1nvpC:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ocm MALONAMIDASE E2

(Bradyrhizobium
japonicum) 		PF01425
(Amidase) 		4 THR A 105
MET A  70
LYS A  44
ILE A 101
 None
 1.35A 2w98B-1ocmA:
undetectable		 2w98B-1ocmA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhh PROTEIN (PCRA
(SUBUNIT))

(Geobacillus
stearothermophilus) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C)
no annotation 		4 THR C 481
GLU C 485
LYS C 490
ILE B 395
 None
 1.40A 2w98B-1qhhC:
undetectable		 2w98B-1qhhC:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qmj BETA-GALACTOSIDE-BIN
DING LECTIN

(Gallus gallus) 		PF00337
(Gal-bind_lectin) 		4 GLU A  95
MET A  42
PHE A  91
ILE A  89
 None
 1.28A 2w98B-1qmjA:
undetectable		 2w98B-1qmjA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svv THREONINE ALDOLASE

(Leishmania
major) 		PF01212
(Beta_elim_lyase) 		4 THR A 339
GLU A 343
PHE A 347
ILE A 279
 None
 1.31A 2w98B-1svvA:
undetectable		 2w98B-1svvA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txg GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Archaeoglobus
fulgidus) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 THR A 116
GLU A 186
LYS A 192
ILE A 232
 None
None
SO4  A1003 (-2.7A)
None
 1.43A 2w98B-1txgA:
7.0		 2w98B-1txgA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		4 GLU A  29
MET A  83
PHE A  68
ILE A  69
 None
 1.43A 2w98B-1v4gA:
undetectable		 2w98B-1v4gA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1woy METHIONYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1)
PF09334
(tRNA-synt_1g) 		4 THR A  96
GLU A  97
PHE A  92
ILE A  11
 None
 1.34A 2w98B-1woyA:
2.2		 2w98B-1woyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE

(Saccharomyces
cerevisiae) 		PF06052
(3-HAO) 		4 THR A  72
GLU A  71
PHE A  78
ILE A  79
 None
 1.32A 2w98B-1zvfA:
undetectable		 2w98B-1zvfA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zwx SPHINGOMYELINASE-C

(Listeria
ivanovii) 		PF03372
(Exo_endo_phos) 		4 THR A 186
MET A 242
PHE A 285
ILE A 226
 None
 1.23A 2w98B-1zwxA:
undetectable		 2w98B-1zwxA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4x ANTITHROMBIN-III

(Homo sapiens) 		PF00079
(Serpin) 		4 THR I 419
GLU I 414
PHE I 221
ILE I 219
 None
 1.37A 2w98B-2b4xI:
undetectable		 2w98B-2b4xI:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c91 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 THR A 227
GLU A 226
LYS A 210
PHE A 220
 GOL  A 361 ( 4.6A)
None
None
None
 1.37A 2w98B-2c91A:
undetectable		 2w98B-2c91A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E

(Methanothermobacter
thermautotrophicus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD) 		4 THR C 167
GLU C 166
PHE C 173
ILE C 164
 None
 1.27A 2w98B-2d6fC:
undetectable		 2w98B-2d6fC:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2go4 UDP-3-O-[3-HYDROXYMY
RISTOYL]
N-ACETYLGLUCOSAMINE
DEACETYLASE

(Aquifex
aeolicus) 		PF03331
(LpxC) 		4 THR A  93
GLU A  95
LYS A  25
ILE A  74
 None
 1.38A 2w98B-2go4A:
undetectable		 2w98B-2go4A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h57 ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
6

(Homo sapiens) 		PF00025
(Arf) 		4 THR A  31
GLU A  56
PHE A  53
ILE A  51
 MG  A 202 ( 3.0A)
None
None
None
 1.44A 2w98B-2h57A:
3.3		 2w98B-2h57A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iip NICOTINAMIDE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		4 GLU A  76
LYS A  55
PHE A  78
ILE A  81
 None
 1.14A 2w98B-2iipA:
5.9		 2w98B-2iipA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0n INVASIN IPAD

(Shigella
flexneri) 		PF06511
(IpaD) 		4 THR A 289
GLU A 288
MET A 256
PHE A 283
 None
 1.33A 2w98B-2j0nA:
undetectable		 2w98B-2j0nA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lkk FATTY ACID-BINDING
PROTEIN, LIVER

(Homo sapiens) 		PF14651
(Lipocalin_7) 		4 GLU A  13
MET A  19
PHE A 120
ILE A 118
 None
OLA  A 128 (-3.5A)
OLA  A 128 ( 4.3A)
None
 1.34A 2w98B-2lkkA:
undetectable		 2w98B-2lkkA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ola O-SUCCINYLBENZOIC
ACID SYNTHETASE

(Staphylococcus
aureus) 		PF13378
(MR_MLE_C) 		4 THR A 102
GLU A  47
PHE A  51
ILE A  61
 None
 1.23A 2w98B-2olaA:
undetectable		 2w98B-2olaA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ran ANNEXIN V

(Rattus
norvegicus) 		PF00191
(Annexin) 		4 THR A 227
GLU A 226
PHE A 217
ILE A 219
 None
CA  A 324 (-2.3A)
None
None
 1.40A 2w98B-2ranA:
undetectable		 2w98B-2ranA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rc5 FERREDOXIN-NADP
REDUCTASE

(Leptospira
interrogans) 		PF00175
(NAD_binding_1) 		4 GLU A 285
MET A 169
PHE A 269
ILE A 271
 None
 1.35A 2w98B-2rc5A:
4.1		 2w98B-2rc5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 THR A 579
GLU A 576
MET A 522
PHE A 505
 PG4  A1595 (-3.9A)
PG4  A1595 (-3.7A)
None
None
 1.31A 2w98B-2v6oA:
undetectable		 2w98B-2v6oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 THR A 580
GLU A 576
MET A 522
PHE A 505
 PG4  A1595 (-4.1A)
PG4  A1595 (-3.7A)
None
None
 1.37A 2w98B-2v6oA:
undetectable		 2w98B-2v6oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3p BENZOYL-COA-DIHYDROD
IOL LYASE

(Paraburkholderia
xenovorans) 		PF00378
(ECH_1) 		4 THR A 391
GLU A 394
MET A 349
ILE A 361
 None
 1.25A 2w98B-2w3pA:
undetectable		 2w98B-2w3pA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wji FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG

(Methanocaldococcus
jannaschii) 		PF02421
(FeoB_N) 		4 THR A  24
GLU A  44
LYS A   1
ILE A   6
 None
 1.25A 2w98B-2wjiA:
2.6		 2w98B-2wjiA:
17.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 THR A  97
GLU A 115
LYS A 293
ILE A 300
 None
 1.38A 2w98B-2zb3A:
34.4		 2w98B-2zb3A:
85.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 THR A  97
GLU A 115
PHE A 296
ILE A 300
 None
 0.88A 2w98B-2zb3A:
34.4		 2w98B-2zb3A:
85.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		5 THR A  97
GLU A 115
LYS A 293
PHE A 296
ILE A 300
 None
 0.64A 2w98B-2zb4A:
57.9		 2w98B-2zb4A:
97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3akk CTKA

(Helicobacter
pylori) 		PF07804
(HipA_C) 		4 THR A  74
GLU A  57
PHE A 178
ILE A 177
 None
None
ADP  A 500 ( 4.5A)
None
 1.41A 2w98B-3akkA:
undetectable		 2w98B-3akkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ba0 MACROPHAGE
METALLOELASTASE

(Homo sapiens) 		PF00045
(Hemopexin)
PF00413
(Peptidase_M10) 		4 THR A 292
GLU A 337
PHE A 345
ILE A 355
 None
 1.30A 2w98B-3ba0A:
undetectable		 2w98B-3ba0A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE

(Escherichia
coli) 		PF00834
(Ribul_P_3_epim) 		4 GLU A 171
MET A   1
PHE A 192
ILE A   3
 None
 1.25A 2w98B-3ct7A:
undetectable		 2w98B-3ct7A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4u CARBOXYPEPTIDASE B2

(Bos taurus) 		PF00246
(Peptidase_M14) 		4 GLU A 292
MET A 195
PHE A  78
ILE A  74
 None
 1.18A 2w98B-3d4uA:
undetectable		 2w98B-3d4uA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e74 ALLANTOINASE

(Escherichia
coli) 		PF01979
(Amidohydro_1) 		4 THR A  60
GLU A  90
LYS A 115
ILE A 118
 None
 1.31A 2w98B-3e74A:
undetectable		 2w98B-3e74A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejb BIOTIN BIOSYNTHESIS
CYTOCHROME P450-LIKE
ENZYME

(Bacillus
subtilis) 		PF00067
(p450) 		4 THR B 227
GLU B 223
MET B 188
ILE B 195
 None
 1.33A 2w98B-3ejbB:
undetectable		 2w98B-3ejbB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ezu GGDEF DOMAIN PROTEIN

(Geobacter
sulfurreducens) 		PF00990
(GGDEF) 		4 THR A 247
GLU A 244
LYS A   0
ILE A  70
 None
 1.38A 2w98B-3ezuA:
undetectable		 2w98B-3ezuA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fkd L-THREONINE-O-3-PHOS
PHATE DECARBOXYLASE

(Porphyromonas
gingivalis) 		PF00155
(Aminotran_1_2) 		4 THR A 337
GLU A 336
MET A 296
PHE A 331
 None
 1.19A 2w98B-3fkdA:
3.9		 2w98B-3fkdA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g79 NDP-N-ACETYL-D-GALAC
TOSAMINURONIC ACID
DEHYDROGENASE

(Methanosarcina
mazei) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 THR A 373
GLU A 376
MET A 358
ILE A 404
 None
 0.90A 2w98B-3g79A:
6.8		 2w98B-3g79A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5p NUCLEOPORIN NUP170

(Saccharomyces
cerevisiae) 		PF03177
(Nucleoporin_C) 		4 GLU A1447
MET A1426
PHE A1416
ILE A1417
 None
 1.18A 2w98B-3i5pA:
undetectable		 2w98B-3i5pA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5q NUCLEOPORIN NUP170

(Saccharomyces
cerevisiae) 		no annotation 4 GLU B1447
MET B1426
PHE B1416
ILE B1417
 None
 1.14A 2w98B-3i5qB:
undetectable		 2w98B-3i5qB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1j ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF05362
(Lon_C)
PF13654
(AAA_32) 		4 THR A 300
GLU A 246
PHE A 243
ILE A 244
 None
 1.33A 2w98B-3k1jA:
undetectable		 2w98B-3k1jA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k55 BETA-HEMOLYSIN

(Staphylococcus
aureus) 		PF03372
(Exo_endo_phos) 		4 THR A 151
MET A 207
PHE A 249
ILE A 191
 None
 1.24A 2w98B-3k55A:
undetectable		 2w98B-3k55A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kpx APOPHOTOPROTEIN
CLYTIN-3

(Clytia gregaria) 		PF13202
(EF-hand_5) 		4 THR A 140
GLU A 137
PHE A 122
ILE A 124
 None
None
CZH  A 201 (-4.6A)
None
 1.16A 2w98B-3kpxA:
undetectable		 2w98B-3kpxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lms CARBOXYPEPTIDASE B2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		4 GLU A 292
MET A 195
PHE A  78
ILE A  74
 None
 1.18A 2w98B-3lmsA:
undetectable		 2w98B-3lmsA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mv3 COATOMER SUBUNIT
ALPHA

(Saccharomyces
cerevisiae) 		PF06957
(COPI_C) 		4 GLU A1043
MET A 994
PHE A1013
ILE A1017
 None
 1.44A 2w98B-3mv3A:
undetectable		 2w98B-3mv3A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n11 CHITINASE A

(Bacillus cereus) 		PF00704
(Glyco_hydro_18) 		4 THR A  69
GLU A  77
LYS A 134
ILE A 128
 None
 1.32A 2w98B-3n11A:
undetectable		 2w98B-3n11A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		PF01547
(SBP_bac_1) 		4 THR A 221
GLU A 244
MET A 490
PHE A 486
 None
 1.42A 2w98B-3ombA:
undetectable		 2w98B-3ombA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3osl CARBOXYPEPTIDASE B2

(Bos taurus) 		PF00246
(Peptidase_M14) 		4 GLU A 407
MET A 309
PHE A 190
ILE A 186
 None
 1.18A 2w98B-3oslA:
undetectable		 2w98B-3oslA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		4 THR A 280
GLU A 276
PHE A 206
ILE A 200
 None
 1.15A 2w98B-3p9uA:
2.8		 2w98B-3p9uA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvz UDP-N-ACETYLGLUCOSAM
INE 4,6-DEHYDRATASE

(Aliivibrio
fischeri) 		PF02719
(Polysacc_synt_2) 		4 THR A 328
GLU A 327
MET A 331
PHE A 255
 None
 1.32A 2w98B-3pvzA:
6.6		 2w98B-3pvzA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qj3 CATHEPSIN L-LIKE
PROTEIN

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 THR A  41
GLU A  40
PHE A  35
ILE A  34
 None
 0.94A 2w98B-3qj3A:
undetectable		 2w98B-3qj3A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 THR A 740
GLU A 742
LYS A 821
ILE A 747
 None
 1.08A 2w98B-3s9vA:
undetectable		 2w98B-3s9vA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shr CGMP-DEPENDENT
PROTEIN KINASE 1

(Bos taurus) 		PF00027
(cNMP_binding) 		4 GLU A 167
MET A 200
LYS A 104
ILE A 114
 CMP  A 401 (-2.8A)
None
None
None
 1.24A 2w98B-3shrA:
undetectable		 2w98B-3shrA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL-COENZYME M
REDUCTASE, BETA
SUBUNIT

(uncultured
archaeon) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 THR B 338
GLU B 335
MET B 295
PHE B 345
 None
 1.22A 2w98B-3sqgB:
undetectable		 2w98B-3sqgB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syj ADHESION AND
PENETRATION PROTEIN
AUTOTRANSPORTER

(Haemophilus
influenzae) 		PF02395
(Peptidase_S6)
PF03212
(Pertactin) 		4 THR A 159
MET A 247
PHE A 276
ILE A 262
 None
 1.30A 2w98B-3syjA:
undetectable		 2w98B-3syjA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thz DNA MISMATCH REPAIR
PROTEIN MSH2

(Homo sapiens) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 THR A 456
GLU A 452
PHE A 450
ILE A 584
 None
 1.27A 2w98B-3thzA:
undetectable		 2w98B-3thzA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4j NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 THR A 198
GLU A 107
PHE A 171
ILE A 175
 None
 1.30A 2w98B-3u4jA:
5.4		 2w98B-3u4jA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uq3 HEAT SHOCK PROTEIN
STI1

(Saccharomyces
cerevisiae) 		PF00515
(TPR_1)
PF13181
(TPR_8)
PF13432
(TPR_16) 		4 THR A 313
GLU A 310
PHE A 278
ILE A 282
 None
 1.25A 2w98B-3uq3A:
undetectable		 2w98B-3uq3A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0v L-LYSINE OXIDASE

(Trichoderma
viride) 		PF01593
(Amino_oxidase) 		4 THR A  45
GLU A  40
PHE A  39
ILE A  12
 None
FAD  A 601 (-2.7A)
None
None
 1.28A 2w98B-3x0vA:
3.2		 2w98B-3x0vA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23

(Clostridium
botulinum;
Homo sapiens) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		4 GLU A 197
MET A 831
LYS A 781
ILE A 827
 None
 1.26A 2w98B-3zusA:
undetectable		 2w98B-3zusA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E

(Streptomyces
cinnabarigriseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLU A 312
MET A 209
PHE A 311
ILE A 309
 None
 0.96A 2w98B-4a0sA:
28.3		 2w98B-4a0sA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0s DEAMIDASE-DEPUPYLASE
DOP

(Acidothermus
cellulolyticus) 		PF03136
(Pup_ligase) 		4 THR A   9
GLU A  99
MET A 122
LYS A  81
 None
MG  A1503 ( 2.0A)
None
None
 1.45A 2w98B-4b0sA:
undetectable		 2w98B-4b0sA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bob ERPP PROTEIN

(Borreliella
burgdorferi) 		PF02471
(OspE) 		4 THR A 150
GLU A 152
PHE A 136
ILE A 122
 None
 1.11A 2w98B-4bobA:
undetectable		 2w98B-4bobA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gi2 CROTONYL-COA
CARBOXYLASE/REDUCTAS
E

(Methylobacterium
extorquens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLU A 308
MET A 199
PHE A 307
ILE A 305
 None
 0.93A 2w98B-4gi2A:
26.4		 2w98B-4gi2A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gk8 HISTIDINOL-PHOSPHATA
SE

(Lactococcus
lactis) 		PF02811
(PHP) 		4 THR A 204
GLU A 205
LYS A 248
ILE A 194
 None
 1.27A 2w98B-4gk8A:
undetectable		 2w98B-4gk8A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h2k SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Haemophilus
influenzae) 		PF01546
(Peptidase_M20) 		4 THR A 131
GLU A 134
PHE A 219
ILE A 220
 None
ZN  A1001 (-3.9A)
None
None
 1.26A 2w98B-4h2kA:
undetectable		 2w98B-4h2kA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8p AMINOALDEHYDE
DEHYDROGENASE 1

(Zea mays) 		PF00171
(Aldedh) 		4 THR A 383
GLU A 405
MET A 316
PHE A 312
 None
 1.14A 2w98B-4i8pA:
2.6		 2w98B-4i8pA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igg CATENIN ALPHA-1

(Homo sapiens) 		PF01044
(Vinculin) 		4 THR A 727
GLU A 725
MET A 826
ILE A 749
 None
 1.33A 2w98B-4iggA:
undetectable		 2w98B-4iggA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igg CATENIN ALPHA-1

(Homo sapiens) 		PF01044
(Vinculin) 		4 THR A 727
MET A 826
LYS A 717
ILE A 749
 None
 1.35A 2w98B-4iggA:
undetectable		 2w98B-4iggA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lk3 UDP-GLUCURONIC ACID
DECARBOXYLASE 1

(Homo sapiens) 		PF16363
(GDP_Man_Dehyd) 		4 GLU A 204
LYS A 361
PHE A 259
ILE A 258
 None
None
None
NAD  A 501 (-3.9A)
 1.03A 2w98B-4lk3A:
5.7		 2w98B-4lk3A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q0m L-ASPARAGINASE

(Pyrococcus
furiosus) 		PF00710
(Asparaginase) 		4 THR A 306
GLU A 311
LYS A 318
ILE A 285
 None
 1.10A 2w98B-4q0mA:
undetectable		 2w98B-4q0mA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D

(Homo sapiens) 		PF12706
(Lactamase_B_2) 		4 THR A 128
GLU A 138
PHE A 144
ILE A 178
 None
 1.44A 2w98B-4qn9A:
undetectable		 2w98B-4qn9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qnl TAIL FIBER PROTEIN

(Escherichia
virus G7C) 		no annotation 4 THR A 794
MET A 845
LYS A 713
ILE A 847
 None
 1.42A 2w98B-4qnlA:
undetectable		 2w98B-4qnlA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN

(Salmonella
enterica) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1) 		4 THR A1611
GLU A1547
PHE A1022
ILE A1113
 None
 0.98A 2w98B-4u48A:
undetectable		 2w98B-4u48A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufc GH95

(Bacteroides
ovatus) 		PF14498
(Glyco_hyd_65N_2) 		4 THR A 602
MET A 625
PHE A 596
ILE A 587
 None
 1.44A 2w98B-4ufcA:
undetectable		 2w98B-4ufcA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wn9 NITROGENASE
MOLYBDENUM-IRON
PROTEIN ALPHA CHAIN

(Clostridium
pasteurianum) 		PF00148
(Oxidored_nitro) 		4 THR A 275
GLU A 271
MET A 194
ILE A 396
 None
 1.22A 2w98B-4wn9A:
undetectable		 2w98B-4wn9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xg1 DIAMINOPIMELATE
DECARBOXYLASE

(Psychromonas
ingrahamii) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 THR A 258
GLU A 255
PHE A 211
ILE A 212
 None
 1.25A 2w98B-4xg1A:
undetectable		 2w98B-4xg1A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF07678
(A2M_comp) 		4 THR A1620
GLU A1556
PHE A1030
ILE A1121
 None
 1.14A 2w98B-4ziuA:
undetectable		 2w98B-4ziuA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a01 O-GLYCOSYLTRANSFERAS
E

(Drosophila
melanogaster) 		PF13374
(TPR_10)
PF13414
(TPR_11)
PF13844
(Glyco_transf_41) 		4 THR A 982
MET A 954
PHE A 732
ILE A 733
 None
None
12V  A2060 (-4.4A)
None
 1.40A 2w98B-5a01A:
3.9		 2w98B-5a01A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		4 THR A1620
GLU A1556
PHE A1030
ILE A1121
 None
 1.04A 2w98B-5a42A:
undetectable		 2w98B-5a42A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cu1 DMSP LYASE

(Ruegeria
pomeroyi) 		PF16867
(DMSP_lyase) 		4 THR A  59
MET A 179
PHE A  69
ILE A  70
 None
 1.34A 2w98B-5cu1A:
undetectable		 2w98B-5cu1A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejh NAD KINASE 1

(Listeria
monocytogenes) 		PF01513
(NAD_kinase) 		4 GLU A 233
LYS A 215
PHE A 217
ILE A 219
 None
 1.36A 2w98B-5ejhA:
undetectable		 2w98B-5ejhA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esr HALOALKANE
DEHALOGENASE

(Caulobacter
vibrioides) 		PF00561
(Abhydrolase_1) 		4 THR A 170
GLU A 172
PHE A 177
ILE A 178
 None
 0.93A 2w98B-5esrA:
3.6		 2w98B-5esrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fur TRANSCRIPTION
INITIATION FACTOR
IIA SUBUNIT 1

(Homo sapiens) 		PF03153
(TFIIA) 		4 MET C 358
LYS C 369
PHE C 367
ILE C 366
 None
 1.39A 2w98B-5furC:
undetectable		 2w98B-5furC:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hd9 ENCAPSIDATION
PROTEIN

(Bacillus virus
phi29) 		PF05894
(Podovirus_Gp16) 		4 THR A 114
GLU A  47
PHE A  42
ILE A  39
 None
 1.26A 2w98B-5hd9A:
2.0		 2w98B-5hd9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hvf CARBOXYPEPTIDASE B2

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 GLU A 385
MET A 287
PHE A 168
ILE A 164
 None
 1.20A 2w98B-5hvfA:
undetectable		 2w98B-5hvfA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 THR A1794
GLU A1791
PHE A1528
ILE A1529
 None
 1.16A 2w98B-5m59A:
2.8		 2w98B-5m59A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n47 FIBRONECTIN

(Homo sapiens) 		no annotation 4 THR B1423
GLU B1424
MET B1374
PHE B1366
 None
 1.42A 2w98B-5n47B:
undetectable		 2w98B-5n47B:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o8r L-LYSINE
6-MONOOXYGENASE
INVOLVED IN
DESFERRIOXAMINE
BIOSYNTHESIS

(Erwinia
amylovora) 		no annotation 4 THR A 385
GLU A 382
PHE A 377
ILE A 370
 None
 1.21A 2w98B-5o8rA:
undetectable		 2w98B-5o8rA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tzk GLYCOSYL TRANSFERASE

(Staphylococcus
aureus) 		PF00535
(Glycos_transf_2) 		4 GLU C 248
MET C 183
PHE C 249
ILE C 232
 None
 1.27A 2w98B-5tzkC:
undetectable		 2w98B-5tzkC:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5urp TOXIN 2A

(Paenibacillus
larvae) 		no annotation 4 THR A 119
GLU A 117
LYS A 194
ILE A 112
 None
 1.25A 2w98B-5urpA:
undetectable		 2w98B-5urpA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9s METHYLPHOSPHONATE
SYNTHASE

(Nitrosopumilus
maritimus) 		no annotation 4 THR A 208
MET A 182
PHE A 162
ILE A 204
 None
 1.38A 2w98B-6b9sA:
undetectable		 2w98B-6b9sA:
14.04