SIMILAR PATTERNS OF AMINO ACIDS FOR 2W98_A_P1ZA1353_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amo NADPH-CYTOCHROME
P450 REDUCTASE

(Rattus
norvegicus) 		PF00175
(NAD_binding_1)
PF00258
(Flavodoxin_1)
PF00667
(FAD_binding_1) 		5 PHE A 223
GLU A 221
GLY A 204
PHE A 216
GLU A 214
 None
 1.08A 2w98A-1amoA:
4.0		 2w98A-1amoA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hc7 PROLYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1) 		5 PHE A  87
GLU A  90
VAL A 141
MET A  74
GLU A 113
 None
 1.47A 2w98A-1hc7A:
undetectable		 2w98A-1hc7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nx8 CARBAPENEM SYNTHASE

(Pectobacterium
carotovorum) 		PF02668
(TauD) 		5 THR A 154
GLU A 153
VAL A 207
PHE A 217
GLU A 213
 None
 1.33A 2w98A-1nx8A:
undetectable		 2w98A-1nx8A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pwe L-SERINE DEHYDRATASE

(Rattus
norvegicus) 		PF00291
(PALP) 		5 THR A  11
VAL A   9
GLY A  38
PHE A  40
ILE A  42
 None
 1.24A 2w98A-1pweA:
4.2		 2w98A-1pweA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxm DNA POLYMERASE
SLIDING CLAMP

(Archaeoglobus
fulgidus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		5 THR A  13
VAL A 228
GLY A 206
PHE A 225
GLU A 226
 None
 1.31A 2w98A-1rxmA:
undetectable		 2w98A-1rxmA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcx UROPORPHYRINOGEN III
SYNTHASE

(Thermus
thermophilus) 		PF02602
(HEM4) 		5 PHE A  31
GLU A  27
GLY A 246
PHE A  22
GLU A  20
 None
 1.22A 2w98A-1wcxA:
4.4		 2w98A-1wcxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xap RETINOIC ACID
RECEPTOR BETA

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 PHE A 192
GLU A 190
GLY A 320
GLU A 182
ILE A 184
 None
 1.34A 2w98A-1xapA:
undetectable		 2w98A-1xapA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zor ISOCITRATE
DEHYDROGENASE

(Thermotoga
maritima) 		PF00180
(Iso_dh) 		5 THR A 321
PHE A 387
VAL A 306
GLY A 284
GLU A 300
 None
 1.25A 2w98A-1zorA:
undetectable		 2w98A-1zorA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eix NADH-CYTOCHROME B5
REDUCTASE

(Physarum
polycephalum) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		5 THR A 184
PHE A 214
VAL A 154
GLY A 158
MET A 159
 None
 1.32A 2w98A-2eixA:
4.5		 2w98A-2eixA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 GLU A 198
GLY A  60
PHE A 239
GLU A 202
ILE A 201
 None
 1.39A 2w98A-2gp6A:
undetectable		 2w98A-2gp6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 GLU A 198
GLY A  61
PHE A 239
GLU A 202
ILE A 201
 None
 1.39A 2w98A-2gp6A:
undetectable		 2w98A-2gp6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p2w CITRATE SYNTHASE

(Thermotoga
maritima) 		PF00285
(Citrate_synt) 		5 PHE A  42
GLU A  44
MET A  67
PHE A  63
GLU A  59
 None
 1.34A 2w98A-2p2wA:
undetectable		 2w98A-2p2wA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyt ETHANOLAMINE
UTILIZATION PROTEIN
EUTQ

(Salmonella
enterica) 		PF06249
(EutQ) 		5 THR A 142
PHE A 131
VAL A 126
PHE A 217
GLU A 179
 None
 1.43A 2w98A-2pytA:
undetectable		 2w98A-2pytA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v0j BIFUNCTIONAL PROTEIN
GLMU

(Haemophilus
influenzae) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		5 PHE A 347
GLU A 349
VAL A 367
GLY A 381
ILE A 383
 None
 1.16A 2w98A-2v0jA:
undetectable		 2w98A-2v0jA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3b ATP-DEPENDENT
PROTEASE HSLV

(Bacillus
subtilis) 		PF00227
(Proteasome) 		5 THR A 162
GLU A 161
GLY A 139
GLU A 154
ILE A 155
 None
 1.35A 2w98A-2z3bA:
undetectable		 2w98A-2z3bA:
18.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		7 THR A  97
PHE A  99
GLU A 115
VAL A 117
PHE A 296
GLU A 297
ILE A 300
 None
 0.97A 2w98A-2zb3A:
34.0		 2w98A-2zb3A:
85.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		7 THR A  97
PHE A  99
VAL A 117
GLY A 134
PHE A 296
GLU A 297
ILE A 300
 None
 0.77A 2w98A-2zb3A:
34.0		 2w98A-2zb3A:
85.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		5 THR A  97
GLU A 115
VAL A 117
GLY A 134
ILE A 300
 None
 0.61A 2w98A-2zb4A:
57.6		 2w98A-2zb4A:
97.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		5 THR A  97
VAL A 117
GLY A 134
PHE A 296
ILE A 300
 None
 0.73A 2w98A-2zb4A:
57.6		 2w98A-2zb4A:
97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn4 CARBON
DIOXIDE-CONCENTRATIN
G MECHANISM PROTEIN
CCMK HOMOLOG 1

(Synechocystis
sp.) 		PF00936
(BMC) 		5 GLU A   9
VAL A  16
GLY A  60
GLU A  71
ILE A  64
 None
 1.27A 2w98A-3bn4A:
undetectable		 2w98A-3bn4A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buz IOTA TOXIN COMPONENT
IA

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		5 THR A 339
PHE A 336
VAL A 293
GLY A 366
ILE A 287
 None
 1.37A 2w98A-3buzA:
undetectable		 2w98A-3buzA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cei SUPEROXIDE DISMUTASE

(Helicobacter
pylori) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		5 PHE A   9
GLY A  15
MET A  14
PHE A  17
GLU A 175
 None
SO4  A 700 ( 3.4A)
None
None
None
 1.40A 2w98A-3ceiA:
undetectable		 2w98A-3ceiA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cny INOSITOL CATABOLISM
PROTEIN IOLE

(Lactobacillus
plantarum) 		PF01261
(AP_endonuc_2) 		5 THR A  47
PHE A  44
GLU A  48
GLY A  17
ILE A  16
 None
 1.38A 2w98A-3cnyA:
undetectable		 2w98A-3cnyA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f9t L-TYROSINE
DECARBOXYLASE MFNA

(Methanocaldococcus
jannaschii) 		PF00282
(Pyridoxal_deC) 		5 THR A 156
GLU A 159
GLY A 176
GLU A 190
ILE A 189
 None
 1.39A 2w98A-3f9tA:
2.2		 2w98A-3f9tA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iz3 STRUCTURAL PROTEIN
VP1

(Cypovirus 1) 		no annotation 5 PHE B 585
VAL B 492
GLY B 530
GLU B 524
ILE B 528
 None
 1.44A 2w98A-3iz3B:
undetectable		 2w98A-3iz3B:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9m CATHEPSIN B

(Homo sapiens) 		PF00112
(Peptidase_C1) 		5 PHE A 174
GLU A 245
VAL A 247
GLY A  33
GLU A  78
 None
 1.49A 2w98A-3k9mA:
undetectable		 2w98A-3k9mA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ki6 CHOLIX TOXIN

(Vibrio cholerae) 		PF09009
(Exotox-A_cataly) 		5 THR A 582
PHE A 570
GLU A 581
VAL A 494
GLY A 585
 None
None
G9L  A   1 (-4.6A)
None
None
 1.42A 2w98A-3ki6A:
undetectable		 2w98A-3ki6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pv2 DEGQ

(Legionella
fallonii) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		5 THR A 184
PHE A 181
VAL A 142
GLY A 206
ILE A 205
 None
 1.35A 2w98A-3pv2A:
undetectable		 2w98A-3pv2A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vjj P9-1

(Rice black
streaked dwarf
virus) 		PF06043
(Reo_P9) 		5 PHE A 309
GLU A 306
GLY A 329
GLU A 301
ILE A 299
 None
 0.97A 2w98A-3vjjA:
undetectable		 2w98A-3vjjA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vns NRPS ADENYLATION
PROTEIN CYTC1

(Streptomyces
sp.) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		5 GLU A 320
VAL A 190
GLY A 306
PHE A 279
ILE A 278
 None
None
AMP  A 601 (-4.7A)
None
None
 1.45A 2w98A-3vnsA:
4.3		 2w98A-3vnsA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amt RENIN

(Homo sapiens) 		PF00026
(Asp)
PF07966
(A1_Propeptide) 		5 GLU A 156
VAL A 131
GLY A 152
PHE A 134
GLU A 121
 None
 1.39A 2w98A-4amtA:
undetectable		 2w98A-4amtA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dok SIMILARITY TO
CHALCONE-FLAVONONE
ISOMERASE

(Arabidopsis
thaliana) 		PF02431
(Chalcone) 		5 GLU A  85
GLY A 154
PHE A 149
GLU A 157
ILE A 155
 None
 1.37A 2w98A-4dokA:
undetectable		 2w98A-4dokA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gc5 DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL

(Mus musculus) 		PF00398
(RrnaAD) 		5 THR A  70
VAL A  83
GLY A  93
PHE A  90
ILE A  91
 None
 1.16A 2w98A-4gc5A:
6.4		 2w98A-4gc5A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nqy ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
LARGE SUBUNIT

(Methanocaldococcus
jannaschii) 		PF00330
(Aconitase) 		5 PHE A 250
VAL A  31
GLY A 110
MET A 241
GLU A  58
 None
 1.21A 2w98A-4nqyA:
undetectable		 2w98A-4nqyA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvw ZNUD

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		5 THR A 504
VAL A 569
GLY A 497
MET A 396
GLU A 492
 None
 1.46A 2w98A-4rvwA:
undetectable		 2w98A-4rvwA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001) 		PF01425
(Amidase) 		5 THR A  34
VAL A 176
GLY A  78
GLU A  15
ILE A  16
 None
 1.45A 2w98A-4yjiA:
undetectable		 2w98A-4yjiA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eft P9-1

(Southern rice
black-streaked
dwarf virus) 		PF06043
(Reo_P9) 		5 PHE B 288
GLU B 285
GLY B 308
GLU B 280
ILE B 278
 None
 1.18A 2w98A-5eftB:
undetectable		 2w98A-5eftB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es6 LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A

(Brevibacillus
parabrevis) 		PF00501
(AMP-binding)
PF00551
(Formyl_trans_N) 		5 VAL A 465
GLY A 480
PHE A 493
GLU A 579
ILE A 504
 None
 1.50A 2w98A-5es6A:
2.1		 2w98A-5es6A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		5 THR A 346
PHE A 376
GLU A 373
VAL A 372
MET A 471
 None
 1.37A 2w98A-5fr8A:
undetectable		 2w98A-5fr8A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikb GLUTAMATE RECEPTOR
IONOTROPIC, KAINATE
4,GLUTAMATE RECEPTOR
IONOTROPIC, KAINATE
4

(Rattus
norvegicus) 		PF10613
(Lig_chan-Glu_bd) 		5 VAL A  60
GLY A 140
MET A 143
PHE A 169
ILE A 137
 None
KAI  A 301 (-3.6A)
None
None
KAI  A 301 (-3.9A)
 1.24A 2w98A-5ikbA:
undetectable		 2w98A-5ikbA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l0z PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY

(Sinorhizobium
meliloti) 		PF00588
(SpoU_methylase)
PF08032
(SpoU_sub_bind) 		5 THR A 170
PHE A 173
VAL A 142
GLY A 149
ILE A 151
 None
 1.48A 2w98A-5l0zA:
2.4		 2w98A-5l0zA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu5 UNCHARACTERIZED
PROTEIN

(Magnetospirillum
magneticum) 		no annotation 5 GLU A 151
VAL A 150
MET A  26
PHE A 154
GLU A 186
 None
 1.48A 2w98A-5mu5A:
5.4		 2w98A-5mu5A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9u DEHYDROASCORBATE
REDUCTASE FAMILY
PROTEIN

(Populus
trichocarpa) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		5 PHE A 109
VAL A 202
GLY A 165
PHE A 167
GLU A 207
 None
 1.48A 2w98A-5n9uA:
undetectable		 2w98A-5n9uA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v96 S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE

(Naegleria
fowleri) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 THR A  70
PHE A 404
GLU A  69
MET A  33
GLU A  27
 None
ADN  A 502 (-4.9A)
None
None
None
 1.37A 2w98A-5v96A:
9.2		 2w98A-5v96A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vzj EXOSOME COMPLEX
EXONUCLEASE RRP6

(Saccharomyces
cerevisiae) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		5 PHE J 281
VAL J 396
GLY J 310
GLU J 184
ILE J 187
 None
 1.44A 2w98A-5vzjJ:
undetectable		 2w98A-5vzjJ:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2

(Leptotrichia
shahii) 		no annotation 5 THR A 308
PHE A 304
PHE A  75
GLU A 205
ILE A 204
 None
 1.38A 2w98A-5wtkA:
undetectable		 2w98A-5wtkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6an0 HISTIDINOL
DEHYDROGENASE

(Elizabethkingia
anophelis) 		PF00815
(Histidinol_dh) 		5 THR A 106
GLU A 107
VAL A 109
GLY A 400
ILE A 396
 None
 1.11A 2w98A-6an0A:
3.6		 2w98A-6an0A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
A, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 5 PHE a 231
VAL a  82
GLY a  99
MET a 101
PHE a  97
 None
 1.46A 2w98A-6fkha:
undetectable		 2w98A-6fkha:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-) 		no annotation 5 THR A  67
PHE A 365
GLU A  66
MET A  30
GLU A  24
 None
 1.31A 2w98A-6gbnA:
9.2		 2w98A-6gbnA:
undetectable