SIMILAR PATTERNS OF AMINO ACIDS FOR 2VXA_B_RBFB200_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e33 | ARYLSULFATASE A (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 4 | ARG P 390TYR P 429ARG P 299ARG P 311 | None | 1.44A | 2vxaA-1e33P:0.02vxaB-1e33P:0.02vxaK-1e33P:undetectable | 2vxaA-1e33P:9.052vxaB-1e33P:9.052vxaK-1e33P:9.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3h | GUANOSINEPENTAPHOSPHATESYNTHETASE (Streptomycesantibioticus) |
PF00013(KH_1)PF01138(RNase_PH)PF03726(PNPase) | 4 | ARG A 397GLN A 388ARG A 384ARG A 442 | SO4 A 902 (-3.7A)NoneNoneSO4 A 902 (-3.9A) | 1.28A | 2vxaA-1e3hA:0.02vxaB-1e3hA:0.02vxaK-1e3hA:0.0 | 2vxaA-1e3hA:6.762vxaB-1e3hA:6.762vxaK-1e3hA:6.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gji | C-REL PROTO-ONCOGENEPROTEIN (Gallus gallus) |
PF00554(RHD_DNA_bind)PF16179(RHD_dimer) | 4 | ARG A 18ARG A 178ARG A 264GLN A 211 | None | 1.43A | 2vxaA-1gjiA:0.02vxaB-1gjiA:0.02vxaK-1gjiA:0.0 | 2vxaA-1gjiA:15.602vxaB-1gjiA:15.602vxaK-1gjiA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT BETA (Desulfovibriogigas) |
PF13247(Fer4_11) | 4 | TYR B 211ARG B 53HIS B 55GLN B 57 | None | 1.33A | 2vxaA-1h0hB:undetectable2vxaB-1h0hB:undetectable2vxaK-1h0hB:0.0 | 2vxaA-1h0hB:13.892vxaB-1h0hB:13.892vxaK-1h0hB:13.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h17 | FORMATEACETYLTRANSFERASE 1 (Escherichiacoli) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | ARG A 176TYR A 735HIS A 704GLN A 703 | OXM A1001 (-3.7A)NoneNoneNone | 1.36A | 2vxaA-1h17A:0.02vxaB-1h17A:0.02vxaK-1h17A:0.0 | 2vxaA-1h17A:7.572vxaB-1h17A:7.572vxaK-1h17A:7.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lns | X-PROLYL DIPEPTIDYLAMINOPEPTIDASE (Lactococcuslactis) |
PF02129(Peptidase_S15)PF08530(PepX_C)PF09168(PepX_N) | 4 | ARG A 447TYR A 381ARG A 435TRP A 444 | None | 1.38A | 2vxaA-1lnsA:0.02vxaB-1lnsA:0.02vxaK-1lnsA:0.0 | 2vxaA-1lnsA:6.192vxaB-1lnsA:6.192vxaK-1lnsA:6.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lrz | FACTOR ESSENTIAL FOREXPRESSION OFMETHICILLINRESISTANCE (Staphylococcusaureus) |
PF02388(FemAB) | 4 | TYR A 328ARG A 228HIS A 29GLN A 25 | None | 1.45A | 2vxaA-1lrzA:0.02vxaB-1lrzA:0.02vxaK-1lrzA:0.0 | 2vxaA-1lrzA:9.142vxaB-1lrzA:9.142vxaK-1lrzA:9.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1na6 | RESTRICTIONENDONUCLEASE ECORII (Escherichiacoli) |
PF09019(EcoRII-C)PF09217(EcoRII-N) | 4 | TYR A 202TRP A 189ARG A 192HIS A 190 | None | 0.84A | 2vxaA-1na6A:0.02vxaB-1na6A:0.02vxaK-1na6A:0.0 | 2vxaA-1na6A:12.002vxaB-1na6A:12.002vxaK-1na6A:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pk0 | CALMODULIN-SENSITIVEADENYLATE CYCLASE (Bacillusanthracis) |
PF03497(Anthrax_toxA) | 4 | ARG A 630TYR A 632ARG A 540GLN A 553 | None | 1.39A | 2vxaA-1pk0A:0.02vxaB-1pk0A:0.02vxaK-1pk0A:0.0 | 2vxaA-1pk0A:10.382vxaB-1pk0A:10.382vxaK-1pk0A:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v4v | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Thermusthermophilus) |
PF02350(Epimerase_2) | 4 | GLN A 67ARG A 45ARG A 78GLN A 82 | None | 1.18A | 2vxaA-1v4vA:undetectable2vxaB-1v4vA:undetectable2vxaK-1v4vA:undetectable | 2vxaA-1v4vA:10.902vxaB-1v4vA:10.902vxaK-1v4vA:10.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcl | HEMOLYTIC LECTINCEL-III (Cucumariaechinata) |
PF00652(Ricin_B_lectin) | 4 | ARG A 14GLN A 44TYR A 36GLN A 230 | None | 1.33A | 2vxaA-1vclA:undetectable2vxaB-1vclA:undetectable2vxaK-1vclA:undetectable | 2vxaA-1vclA:10.382vxaB-1vclA:10.382vxaK-1vclA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfd | DIPEPTIDYLAMINOPEPTIDASE-LIKEPROTEIN 6 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | ARG A 512TYR A 515ARG A 525HIS A 462 | None | 1.23A | 2vxaA-1xfdA:0.22vxaB-1xfdA:undetectable2vxaK-1xfdA:0.1 | 2vxaA-1xfdA:7.342vxaB-1xfdA:7.342vxaK-1xfdA:7.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfu | CALMODULIN-SENSITIVEADENYLATE CYCLASE (Bacillusanthracis) |
PF03497(Anthrax_toxA)PF07737(ATLF) | 4 | ARG A 630TYR A 632ARG A 540GLN A 553 | None | 1.42A | 2vxaA-1xfuA:undetectable2vxaB-1xfuA:undetectable2vxaK-1xfuA:undetectable | 2vxaA-1xfuA:7.402vxaB-1xfuA:7.402vxaK-1xfuA:7.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr4 | PUTATIVE CITRATELYASE ALPHACHAIN/CITRATE-ACPTRANSFERASE (Salmonellaenterica) |
PF04223(CitF) | 4 | GLN A 150ARG A 145ARG A 493HIS A 140 | None | 1.41A | 2vxaA-1xr4A:undetectable2vxaB-1xr4A:undetectable2vxaK-1xr4A:undetectable | 2vxaA-1xr4A:12.202vxaB-1xr4A:12.202vxaK-1xr4A:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6o | FERRITIN HEAVY CHAIN (Trichoplusia ni) |
PF00210(Ferritin) | 4 | GLN M 157TYR M 154ARG M 124GLN M 28 | None | 1.38A | 2vxaA-1z6oM:undetectable2vxaB-1z6oM:undetectable2vxaK-1z6oM:undetectable | 2vxaA-1z6oM:18.672vxaB-1z6oM:18.672vxaK-1z6oM:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5m | DAMAGE-SPECIFIC DNABINDING PROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 4 | ARG A 391GLN A 372ARG A 369HIS A 797 | None | 1.04A | 2vxaA-2b5mA:undetectable2vxaB-2b5mA:undetectable2vxaK-2b5mA:undetectable | 2vxaA-2b5mA:5.692vxaB-2b5mA:5.692vxaK-2b5mA:5.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qrx | GM27569P (Drosophilamelanogaster) |
PF01997(Translin) | 4 | ARG A 98GLN A 147HIS A 49GLN A 46 | None | 1.47A | 2vxaA-2qrxA:undetectable2vxaB-2qrxA:undetectable2vxaK-2qrxA:undetectable | 2vxaA-2qrxA:14.292vxaB-2qrxA:14.292vxaK-2qrxA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4f | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME AREDUCTASE (Homo sapiens) |
PF00368(HMG-CoA_red) | 4 | ARG A 650GLN A 632ARG A 702ARG A 836 | None | 1.33A | 2vxaA-2r4fA:0.62vxaB-2r4fA:0.62vxaK-2r4fA:0.6 | 2vxaA-2r4fA:9.562vxaB-2r4fA:9.562vxaK-2r4fA:9.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9l | PUTATIVE DNALIGASE-LIKE PROTEIN (Mycobacteriumtuberculosis) |
no annotation | 4 | ARG A 47ARG A 244ARG A 133HIS A 178 | NoneEDO A 296 (-4.4A)NoneNone | 1.45A | 2vxaA-2r9lA:undetectable2vxaB-2r9lA:undetectable2vxaK-2r9lA:undetectable | 2vxaA-2r9lA:13.192vxaB-2r9lA:13.192vxaK-2r9lA:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vou | 2,6-DIHYDROXYPYRIDINE HYDROXYLASE (Paenarthrobacternicotinovorans) |
PF00070(Pyr_redox) | 4 | ARG A 340ARG A 295HIS A 298GLN A 125 | None | 1.39A | 2vxaA-2vouA:undetectable2vxaB-2vouA:undetectable2vxaK-2vouA:undetectable | 2vxaA-2vouA:13.332vxaB-2vouA:13.332vxaK-2vouA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wpg | AMYLOSUCRASE ORALPHA AMYLASE (Xanthomonascampestris) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 4 | ARG A 573GLN A 364TYR A 629ARG A 470 | None | 1.07A | 2vxaA-2wpgA:undetectable2vxaB-2wpgA:undetectable2vxaK-2wpgA:undetectable | 2vxaA-2wpgA:7.062vxaB-2wpgA:7.062vxaK-2wpgA:7.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xlr | FLAVIN-CONTAININGMONOOXYGENASE (Methylophagaaminisulfidivorans) |
PF00743(FMO-like) | 4 | ARG A 105TRP A 52HIS A 68GLN A 45 | NoneFAD A 500 (-4.2A)FAD A 500 (-3.4A)FAD A 500 (-4.2A) | 1.49A | 2vxaA-2xlrA:undetectable2vxaB-2xlrA:undetectable2vxaK-2xlrA:undetectable | 2vxaA-2xlrA:8.992vxaB-2xlrA:8.992vxaK-2xlrA:8.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e49 | UNCHARACTERIZEDPROTEIN DUF849 WITHA TIM BARREL FOLD (Paraburkholderiaxenovorans) |
PF05853(BKACE) | 4 | TYR A 173ARG A 97HIS A 51GLN A 62 | NoneNone ZN A 500 (-3.4A)None | 1.42A | 2vxaA-3e49A:undetectable2vxaB-3e49A:undetectable2vxaK-3e49A:undetectable | 2vxaA-3e49A:14.192vxaB-3e49A:14.192vxaK-3e49A:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ec4 | PUTATIVEACETYLTRANSFERASEFROM THE GNAT FAMILY (Novosphingobiumaromaticivorans) |
PF08445(FR47) | 4 | ARG A 151TYR A 36ARG A 129GLN A 132 | NoneNoneNoneACT A 229 ( 4.4A) | 1.12A | 2vxaA-3ec4A:0.72vxaB-3ec4A:0.72vxaK-3ec4A:0.7 | 2vxaA-3ec4A:16.302vxaB-3ec4A:16.302vxaK-3ec4A:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fhc | ATP-DEPENDENT RNAHELICASE DDX19BNUCLEAR PORE COMPLEXPROTEIN NUP214 (Homo sapiens) |
PF00270(DEAD)PF12894(ANAPC4_WD40) | 4 | ARG A 20GLN A 18ARG A 348HIS B 253 | None | 1.33A | 2vxaA-3fhcA:undetectable2vxaB-3fhcA:undetectable2vxaK-3fhcA:undetectable | 2vxaA-3fhcA:10.032vxaB-3fhcA:10.032vxaK-3fhcA:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h9c | METHIONYL-TRNASYNTHETASE (Escherichiacoli) |
PF09334(tRNA-synt_1g) | 4 | GLN A 213ARG A 435HIS A 323GLN A 30 | None | 1.01A | 2vxaA-3h9cA:undetectable2vxaB-3h9cA:undetectable2vxaK-3h9cA:undetectable | 2vxaA-3h9cA:9.162vxaB-3h9cA:9.162vxaK-3h9cA:9.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjr | EXTRACELLULAR SERINEPROTEASE (Aeromonassobria) |
PF00082(Peptidase_S8)PF01483(P_proprotein) | 4 | ARG A 577GLN A 517ARG A 580GLN A 581 | None | 1.49A | 2vxaA-3hjrA:undetectable2vxaB-3hjrA:undetectable2vxaK-3hjrA:undetectable | 2vxaA-3hjrA:8.892vxaB-3hjrA:8.892vxaK-3hjrA:8.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrr | AFLATOXINBIOSYNTHESISPOLYKETIDE SYNTHASE (Aspergillusparasiticus) |
PF14765(PS-DH) | 4 | ARG A1618GLN A1575TYR A1577ARG A1461 | None | 1.46A | 2vxaA-3hrrA:0.72vxaB-3hrrA:0.72vxaK-3hrrA:0.7 | 2vxaA-3hrrA:11.592vxaB-3hrrA:11.592vxaK-3hrrA:11.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3muo | PROLYL ENDOPEPTIDASE (Aeromonascaviae) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 4 | GLN A 58TYR A 679HIS A 645GLN A 647 | NoneSUC A 703 (-3.9A)NoneNone | 1.19A | 2vxaA-3muoA:undetectable2vxaB-3muoA:undetectable2vxaK-3muoA:undetectable | 2vxaA-3muoA:7.152vxaB-3muoA:7.152vxaK-3muoA:7.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w0s | HYGROMYCIN-B4-O-KINASE (Escherichiacoli) |
PF01636(APH) | 4 | GLN A 245ARG A 252HIS A 253GLN A 226 | None | 1.30A | 2vxaA-3w0sA:1.62vxaB-3w0sA:1.62vxaK-3w0sA:1.6 | 2vxaA-3w0sA:12.072vxaB-3w0sA:12.072vxaK-3w0sA:12.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ays | AMYLOSUCRASE (Deinococcusradiodurans) |
PF00128(Alpha-amylase) | 4 | ARG A 440TYR A 417TRP A 392HIS A 409 | None | 1.46A | 2vxaA-4aysA:undetectable2vxaB-4aysA:undetectable2vxaK-4aysA:undetectable | 2vxaA-4aysA:8.182vxaB-4aysA:8.182vxaK-4aysA:8.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4boc | DNA-DIRECTED RNAPOLYMERASE,MITOCHONDRIAL (Homo sapiens) |
PF00940(RNA_pol)PF14700(RPOL_N) | 4 | ARG A 516GLN A 522HIS A 659GLN A 565 | None | 1.36A | 2vxaA-4bocA:undetectable2vxaB-4bocA:undetectable2vxaK-4bocA:undetectable | 2vxaA-4bocA:4.912vxaB-4bocA:4.912vxaK-4bocA:4.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by9 | NOP5/NOP56 RELATEDPROTEIN (Pyrococcusfuriosus) |
PF01798(Nop) | 4 | ARG C 322ARG C 327HIS C 305GLN C 284 | G B 51 ( 3.3A) U B 48 ( 2.6A) G B 51 ( 4.7A) C B 27 ( 2.2A) | 0.99A | 2vxaA-4by9C:undetectable2vxaB-4by9C:undetectable2vxaK-4by9C:undetectable | 2vxaA-4by9C:16.062vxaB-4by9C:16.062vxaK-4by9C:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhi | UBIQUITINTHIOESTERASEOTUBAIN-LIKE (Caenorhabditiselegans) |
PF10275(Peptidase_C65) | 4 | TYR B 157ARG B 80ARG B 83GLN B 38 | None | 1.39A | 2vxaA-4dhiB:undetectable2vxaB-4dhiB:undetectable2vxaK-4dhiB:undetectable | 2vxaA-4dhiB:13.072vxaB-4dhiB:13.072vxaK-4dhiB:13.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g54 | GENERAL SECRETIONPATHWAY PROTEIN (Vibriovulnificus) |
PF01471(PG_binding_1) | 4 | ARG A 460GLN A 525ARG A 523GLN A 388 | None | 1.44A | 2vxaA-4g54A:undetectable2vxaB-4g54A:undetectable2vxaK-4g54A:undetectable | 2vxaA-4g54A:14.172vxaB-4g54A:14.172vxaK-4g54A:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jl0 | REGULATORY PROTEINPCRH (Pseudomonasaeruginosa) |
PF07720(TPR_3) | 4 | GLN A 48ARG A 105HIS A 109GLN A 81 | None | 1.31A | 2vxaA-4jl0A:undetectable2vxaB-4jl0A:undetectable2vxaK-4jl0A:undetectable | 2vxaA-4jl0A:17.272vxaB-4jl0A:17.272vxaK-4jl0A:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mh0 | RAP GUANINENUCLEOTIDE EXCHANGEFACTOR 4RAS-RELATED PROTEINRAP-1B (Homo sapiens;Mus musculus) |
PF00027(cNMP_binding)PF00071(Ras)PF00617(RasGEF)PF00618(RasGEF_N) | 4 | ARG E 979GLN E 983ARG E 859GLN R 99 | None | 1.48A | 2vxaA-4mh0E:undetectable2vxaB-4mh0E:undetectable2vxaK-4mh0E:undetectable | 2vxaA-4mh0E:7.102vxaB-4mh0E:7.102vxaK-4mh0E:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr4 | TYPE IIIIODOTHYRONINEDEIODINASE (Mus musculus) |
PF00837(T4_deiodinase) | 4 | ARG A 291GLN A 295TYR A 292TRP A 288 | None | 1.30A | 2vxaA-4tr4A:undetectable2vxaB-4tr4A:undetectable2vxaK-4tr4A:undetectable | 2vxaA-4tr4A:15.472vxaB-4tr4A:15.472vxaK-4tr4A:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjl | INACTIVE DIPEPTIDYLPEPTIDASE 10 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | ARG A 450TYR A 453ARG A 463HIS A 400 | None | 1.43A | 2vxaA-4wjlA:undetectable2vxaB-4wjlA:undetectable2vxaK-4wjlA:undetectable | 2vxaA-4wjlA:7.232vxaB-4wjlA:7.232vxaK-4wjlA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9i | PROTEIN RELATED TOPENICILLIN ACYLASE (Acidovorax sp.MR-S7) |
PF01804(Penicil_amidase) | 4 | GLN A 176TYR A 326TRP A 345GLN A 347 | None | 1.14A | 2vxaA-5c9iA:undetectable2vxaB-5c9iA:undetectable2vxaK-5c9iA:undetectable | 2vxaA-5c9iA:6.482vxaB-5c9iA:6.482vxaK-5c9iA:6.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e0e | CYTOCHROME P450FAMILY 2 SUBFAMILY B (Neotoma lepida) |
PF00067(p450) | 4 | GLN A 400TYR A 401ARG A 85ARG A 59 | None | 1.13A | 2vxaA-5e0eA:undetectable2vxaB-5e0eA:undetectable2vxaK-5e0eA:undetectable | 2vxaA-5e0eA:9.192vxaB-5e0eA:9.192vxaK-5e0eA:9.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej1 | PUTATIVE CELLULOSESYNTHASE (Rhodobactersphaeroides) |
PF00535(Glycos_transf_2)PF03552(Cellulose_synt)PF07238(PilZ) | 4 | GLN A 285TYR A 479ARG A 471ARG A 715 | NoneNoneBGC A 915 ( 2.8A)None | 1.42A | 2vxaA-5ej1A:undetectable2vxaB-5ej1A:undetectable2vxaK-5ej1A:undetectable | 2vxaA-5ej1A:10.052vxaB-5ej1A:10.052vxaK-5ej1A:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jpz | SQUAMOUS CELLCARCINOMA ANTIGENRECOGNIZED BYT-CELLS 3 (Homo sapiens) |
no annotation | 4 | GLN A 330TYR A 353ARG A 370HIS A 368 | None | 1.42A | 2vxaA-5jpzA:undetectable2vxaB-5jpzA:undetectable2vxaK-5jpzA:undetectable | 2vxaA-5jpzA:9.702vxaB-5jpzA:9.702vxaK-5jpzA:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nz7 | CELLODEXTRINPHOSPHORYLASE (Ruminiclostridiumthermocellum) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | GLN A 490ARG A 167ARG A 199GLN A 200 | None | 1.11A | 2vxaA-5nz7A:undetectable2vxaB-5nz7A:undetectable2vxaK-5nz7A:undetectable | 2vxaA-5nz7A:5.462vxaB-5nz7A:5.462vxaK-5nz7A:5.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t2o | I-ONUI_E-AG011377 (syntheticconstruct) |
PF00961(LAGLIDADG_1) | 4 | ARG A 232TRP A 234HIS A 205GLN A 204 | NoneNoneNone CA A 401 ( 4.2A) | 1.49A | 2vxaA-5t2oA:undetectable2vxaB-5t2oA:undetectable2vxaK-5t2oA:undetectable | 2vxaA-5t2oA:13.542vxaB-5t2oA:13.542vxaK-5t2oA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t81 | EPOB (Sorangiumcellulosum) |
PF00668(Condensation) | 4 | GLN A 431TYR A 101ARG A 99HIS A 287 | None | 1.21A | 2vxaA-5t81A:undetectable2vxaB-5t81A:undetectable2vxaK-5t81A:undetectable | 2vxaA-5t81A:8.212vxaB-5t81A:8.212vxaK-5t81A:8.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u03 | CTP SYNTHASE 1 (Homo sapiens) |
PF00117(GATase)PF06418(CTP_synth_N) | 4 | ARG A 269GLN A 240ARG A 205GLN A 167 | None | 1.49A | 2vxaA-5u03A:undetectable2vxaB-5u03A:undetectable2vxaK-5u03A:undetectable | 2vxaA-5u03A:8.122vxaB-5u03A:8.122vxaK-5u03A:8.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1n | VANILLATE/3-O-METHYLGALLATEO-DEMETHYLASE (Sphingobium sp.SYK-6) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | ARG A 227GLN A 223ARG A 163HIS A 60 | NoneNoneTHG A 501 ( 4.4A)DHB A 502 (-4.3A) | 1.31A | 2vxaA-5x1nA:undetectable2vxaB-5x1nA:undetectable2vxaK-5x1nA:undetectable | 2vxaA-5x1nA:9.252vxaB-5x1nA:9.252vxaK-5x1nA:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b0k | IOTA-CARRAGEENANSULFATASE (Pseudoalteromonas) |
no annotation | 4 | ARG A 146TYR A 226ARG A 82TRP A 133 | None | 1.48A | 2vxaA-6b0kA:undetectable2vxaB-6b0kA:undetectable2vxaK-6b0kA:undetectable | 2vxaA-6b0kA:17.652vxaB-6b0kA:17.652vxaK-6b0kA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b0k | IOTA-CARRAGEENANSULFATASE (Pseudoalteromonas) |
no annotation | 4 | ARG A 146TYR A 226TRP A 133HIS A 134 | NoneNoneNoneG4S A 503 ( 4.2A) | 1.47A | 2vxaA-6b0kA:undetectable2vxaB-6b0kA:undetectable2vxaK-6b0kA:undetectable | 2vxaA-6b0kA:17.652vxaB-6b0kA:17.652vxaK-6b0kA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fuy | VINCULIN (Homo sapiens) |
no annotation | 4 | GLN A 994TRP A 253ARG A 987HIS A 187 | None | 1.30A | 2vxaA-6fuyA:undetectable2vxaB-6fuyA:undetectable2vxaK-6fuyA:undetectable | 2vxaA-6fuyA:24.712vxaB-6fuyA:24.712vxaK-6fuyA:24.71 |