SIMILAR PATTERNS OF AMINO ACIDS FOR 2VQ5_B_LDPB1197

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1af5 I-CREI

(Chlamydomonas
reinhardtii) 		PF00961
(LAGLIDADG_1) 		4 LEU A  13
LEU A  10
PHE A   9
LEU A  58
 None
 0.91A 2vq5B-1af5A:
undetectable		 2vq5B-1af5A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b1y PROTEIN
(BETA-AMYLASE)

(Hordeum vulgare) 		PF01373
(Glyco_hydro_14) 		4 LEU A  76
LEU A  73
PHE A  27
PRO A  17
 None
 0.95A 2vq5B-1b1yA:
0.0		 2vq5B-1b1yA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cxz PROTEIN (PKN)

(Homo sapiens) 		PF02185
(HR1) 		4 LEU B  42
LEU B  87
LEU B  94
GLU B  93
 None
 0.93A 2vq5B-1cxzB:
undetectable		 2vq5B-1cxzB:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6v CHIMERIC GERMLINE
PRECURSOR OF
OXY-COPE CATALYTIC
ANTIBODY AZ-28
(LIGHT CHAIN)

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 175
LEU L 136
PHE L 139
GLU L 143
 None
 0.94A 2vq5B-1d6vL:
undetectable		 2vq5B-1d6vL:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee8 MUTM (FPG) PROTEIN

(Thermus
thermophilus) 		PF01149
(Fapy_DNA_glyco)
PF06827
(zf-FPG_IleRS)
PF06831
(H2TH) 		4 LEU A 190
LEU A 194
PHE A 135
LEU A 182
 None
 0.88A 2vq5B-1ee8A:
0.7		 2vq5B-1ee8A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fps FARNESYL DIPHOSPHATE
SYNTHASE

(Gallus gallus) 		PF00348
(polyprenyl_synt) 		4 LEU A 170
LEU A 173
PHE A 174
PRO A 223
 None
 0.85A 2vq5B-1fpsA:
0.0		 2vq5B-1fpsA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3b ATP-DEPENDENT
PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Thermus
thermophilus) 		PF01293
(PEPCK_ATP) 		5 LEU A 353
LEU A 502
PHE A 467
LEU A 423
TYR A 366
 None
 1.35A 2vq5B-1j3bA:
0.0		 2vq5B-1j3bA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC

(Escherichia
coli) 		PF10411
(DsbC_N)
PF13098
(Thioredoxin_2) 		4 LEU A 173
LEU A 177
PHE A  93
LEU A  74
 None
 0.92A 2vq5B-1jzoA:
0.1		 2vq5B-1jzoA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k38 BETA-LACTAMASE OXA-2

(Salmonella
enterica) 		PF00905
(Transpeptidase) 		4 LEU A 173
LEU A 170
PHE A 169
LEU A  75
 None
 0.82A 2vq5B-1k38A:
0.0		 2vq5B-1k38A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kbl PYRUVATE PHOSPHATE
DIKINASE

([Clostridium]
symbiosum) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 LEU A 109
LEU A  72
GLU A  73
PRO A 200
 None
 0.95A 2vq5B-1kblA:
0.0		 2vq5B-1kblA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kps RAN-GTPASE
ACTIVATING PROTEIN 1

(Mus musculus) 		PF07834
(RanGAP1_C) 		4 LEU B 518
PHE B 514
LEU B 499
TYR B 552
 None
 0.97A 2vq5B-1kpsB:
undetectable		 2vq5B-1kpsB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1l SUPPRESSOR OF FUSED

(Homo sapiens) 		PF05076
(SUFU) 		4 LEU A 120
LEU A  95
PHE A 118
LEU A 179
 None
 0.93A 2vq5B-1m1lA:
undetectable		 2vq5B-1m1lA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oe5 SINGLE-STRAND
SELECTIVE
MONOFUNCTIONAL
URACIL DNA
GLYCOSYLASE

(Xenopus laevis) 		no annotation 4 LEU A 201
LEU A 193
PHE A  58
LEU A  53
 None
 0.92A 2vq5B-1oe5A:
undetectable		 2vq5B-1oe5A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qyn PROTEIN-EXPORT
PROTEIN SECB

(Escherichia
coli) 		PF02556
(SecB) 		4 LEU A  44
LEU A  60
PHE A 133
PRO A 108
 None
 0.99A 2vq5B-1qynA:
undetectable		 2vq5B-1qynA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9i DNA ENDONUCLEASE
I-CREI

(Chlamydomonas
reinhardtii) 		PF00961
(LAGLIDADG_1) 		4 LEU A  13
LEU A  10
PHE A   9
LEU A  58
 None
 0.97A 2vq5B-1t9iA:
undetectable		 2vq5B-1t9iA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ufa TT1467 PROTEIN

(Thermus
thermophilus) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 LEU A   8
LEU A  57
PHE A  55
LEU A 368
 None
 0.96A 2vq5B-1ufaA:
undetectable		 2vq5B-1ufaA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT

(Pyrococcus
horikoshii) 		PF01896
(DNA_primase_S) 		4 LEU A 267
LEU A 264
LEU A 222
PRO A 256
 None
 0.80A 2vq5B-1v33A:
undetectable		 2vq5B-1v33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc9 NDX1

(Thermus
thermophilus) 		PF00293
(NUDIX) 		5 LEU A 108
LEU A  18
PHE A  28
GLU A 118
PRO A 101
 None
 1.41A 2vq5B-1vc9A:
undetectable		 2vq5B-1vc9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		4 LEU A 138
LEU A 134
PHE A 137
GLU A 484
 None
None
DTT  A1717 (-4.9A)
DTT  A1717 ( 3.9A)
 0.66A 2vq5B-1w27A:
undetectable		 2vq5B-1w27A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1e 2-DEOXY-D-GLUCONATE
3-DEHYDROGENASE

(Thermus
thermophilus) 		PF13561
(adh_short_C2) 		4 LEU A 154
LEU A 158
PHE A 126
LEU A 102
 None
 1.00A 2vq5B-1x1eA:
undetectable		 2vq5B-1x1eA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xs5 MEMBRANE LIPOPROTEIN
TPN32

(Treponema
pallidum) 		PF03180
(Lipoprotein_9) 		4 LEU A 124
LEU A 121
LEU A  91
PRO A 111
 None
 0.87A 2vq5B-1xs5A:
undetectable		 2vq5B-1xs5A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8q UBIQUITIN-LIKE 2
ACTIVATING ENZYME
E1B

(Homo sapiens) 		PF00899
(ThiF)
PF14732
(UAE_UbL)
PF16195
(UBA2_C) 		4 LEU B 192
LEU B 196
PHE B 354
PRO B 251
 None
 1.00A 2vq5B-1y8qB:
undetectable		 2vq5B-1y8qB:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygg PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Actinobacillus
succinogenes) 		PF01293
(PEPCK_ATP) 		5 LEU A 368
LEU A 513
PHE A 478
LEU A 438
TYR A 381
 None
 1.42A 2vq5B-1yggA:
undetectable		 2vq5B-1yggA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1w TRICORN PROTEASE
INTERACTING FACTOR
F3

(Thermoplasma
acidophilum) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 LEU A 511
LEU A 515
PHE A 536
LEU A 503
 None
 0.98A 2vq5B-1z1wA:
undetectable		 2vq5B-1z1wA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2am2 UDP-N-ACETYLMURAMOYL
ALANINE-D-GLUTAMYL-L
YSINE-D-ALANYL-D-ALA
NINE LIGASE, MURF
PROTEIN

(Streptococcus
pneumoniae) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 LEU A 265
LEU A 267
PHE A 256
LEU A 261
 None
 0.91A 2vq5B-2am2A:
undetectable		 2vq5B-2am2A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2avd CATECHOL-O-METHYLTRA
NSFERASE

(Homo sapiens) 		PF01596
(Methyltransf_3) 		4 LEU A  97
LEU A 100
LEU A 258
TYR A 246
 None
 0.78A 2vq5B-2avdA:
undetectable		 2vq5B-2avdA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b42 XYLANASE INHIBITOR-I

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 LEU A 166
LEU A 358
PHE A 360
LEU A 143
 None
 0.98A 2vq5B-2b42A:
undetectable		 2vq5B-2b42A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5d ALPHA-AMYLASE

(Thermotoga
maritima) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 LEU X  53
LEU X 137
PHE X  45
LEU X 364
 None
 0.86A 2vq5B-2b5dX:
undetectable		 2vq5B-2b5dX:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bfe 2-OXOISOVALERATE
DEHYDROGENASE ALPHA
SUBUNIT

(Homo sapiens) 		PF00676
(E1_dh) 		4 LEU A 382
LEU A 386
LEU A 363
PRO A 394
 None
 0.99A 2vq5B-2bfeA:
undetectable		 2vq5B-2bfeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bx7 DIHYDROOROTATE
DEHYDROGENASE

(Lactococcus
lactis) 		PF01180
(DHO_dh) 		4 LEU A 161
LEU A 186
PHE A 154
LEU A 112
 None
 0.95A 2vq5B-2bx7A:
undetectable		 2vq5B-2bx7A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c79 GLYCOSIDE HYDROLASE,
FAMILY
11:CLOSTRIDIUM
CELLULOSOME ENZYME,
DOCKERIN TYPE
I:POLYSACCHARIDE

(Ruminiclostridium
thermocellum) 		PF01522
(Polysacc_deac_1) 		4 LEU A 484
LEU A 629
PHE A 486
PRO A 640
 None
 0.98A 2vq5B-2c79A:
undetectable		 2vq5B-2c79A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw5 BACTERIAL
FLUORINATING ENZYME
HOMOLOG

(Thermus
thermophilus) 		PF01887
(SAM_adeno_trans) 		4 LEU A  98
LEU A 101
LEU A 179
GLU A 177
 None
 0.98A 2vq5B-2cw5A:
undetectable		 2vq5B-2cw5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1c ISOCITRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 LEU A 325
LEU A 321
LEU A 331
PRO A 294
 None
 0.86A 2vq5B-2d1cA:
undetectable		 2vq5B-2d1cA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4r HYPOTHETICAL PROTEIN
TTHA0849

(Thermus
thermophilus) 		PF03364
(Polyketide_cyc) 		4 LEU A  37
LEU A  31
TYR A  87
GLU A  64
 None
 0.76A 2vq5B-2d4rA:
13.3		 2vq5B-2d4rA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dc0 PROBABLE AMIDASE

(Thermus
thermophilus) 		PF01425
(Amidase) 		4 LEU A  68
LEU A  65
LEU A  10
GLU A  11
 None
 0.94A 2vq5B-2dc0A:
undetectable		 2vq5B-2dc0A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dt8 DEGV FAMILY PROTEIN

(Thermus
thermophilus) 		PF02645
(DegV) 		4 LEU A  17
LEU A  21
LEU A 256
GLU A 254
 None
 0.90A 2vq5B-2dt8A:
undetectable		 2vq5B-2dt8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6k TRANSKETOLASE

(Thermus
thermophilus) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 137
PHE A 141
LEU A 331
PRO A 367
 None
 0.96A 2vq5B-2e6kA:
undetectable		 2vq5B-2e6kA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6k TRANSKETOLASE

(Thermus
thermophilus) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 156
LEU A  66
PHE A  64
LEU A  40
 None
 0.95A 2vq5B-2e6kA:
undetectable		 2vq5B-2e6kA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erx GTP-BINDING PROTEIN
DI-RAS2

(Homo sapiens) 		PF00071
(Ras) 		4 LEU A 161
LEU A 165
PHE A 162
LEU A  23
 None
 0.99A 2vq5B-2erxA:
undetectable		 2vq5B-2erxA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Homo sapiens) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 244
LEU A 216
PHE A 221
LEU A 248
 None
 0.95A 2vq5B-2g76A:
undetectable		 2vq5B-2g76A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf0 GTP-BINDING PROTEIN
DI-RAS1

(Homo sapiens) 		PF00071
(Ras) 		4 LEU A 160
LEU A 164
PHE A 161
LEU A  23
 None
 0.98A 2vq5B-2gf0A:
undetectable		 2vq5B-2gf0A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsc PUTATIVE
UNCHARACTERIZED
PROTEIN XCC0516

(Xanthomonas
campestris) 		PF05635
(23S_rRNA_IVP) 		4 LEU A  42
LEU A  46
PHE A  34
LEU A  93
 None
 0.87A 2vq5B-2gscA:
undetectable		 2vq5B-2gscA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gt2 GDP-MANNOSE MANNOSYL
HYDROLASE

(Escherichia
coli) 		PF00293
(NUDIX) 		4 LEU A  21
LEU A 106
PHE A 108
GLU A  60
 None
 0.93A 2vq5B-2gt2A:
undetectable		 2vq5B-2gt2A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h3g BIOSYNTHETIC PROTEIN

(Bacillus
anthracis) 		PF03309
(Pan_kinase) 		4 LEU X  14
LEU X   5
PHE X   3
LEU X  46
 None
 0.94A 2vq5B-2h3gX:
undetectable		 2vq5B-2h3gX:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzk TRAP-T FAMILY
SORBITOL/MANNITOL
TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN, SMOM

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		4 LEU A 265
LEU A 257
PHE A  66
LEU A  54
 None
 0.91A 2vq5B-2hzkA:
undetectable		 2vq5B-2hzkA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iop CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 LEU A 601
LEU A 608
LEU A 597
GLU A 594
 None
 0.86A 2vq5B-2iopA:
undetectable		 2vq5B-2iopA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iy4 NON-HEME
IRON-CONTAINING
FERRITIN

(Listeria
monocytogenes) 		PF00210
(Ferritin) 		4 LEU A 106
LEU A 102
PHE A  23
GLU A  52
 None
 0.90A 2vq5B-2iy4A:
undetectable		 2vq5B-2iy4A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0j FOCAL ADHESION
KINASE 1

(Gallus gallus) 		PF00373
(FERM_M)
PF07714
(Pkinase_Tyr) 		4 LEU A 523
LEU A 520
LEU A 511
PRO A 645
 None
 0.97A 2vq5B-2j0jA:
undetectable		 2vq5B-2j0jA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l21 CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Gallus gallus) 		PF00878
(CIMR) 		4 LEU A1906
LEU A1909
LEU A1970
PRO A2004
 None
 0.81A 2vq5B-2l21A:
undetectable		 2vq5B-2l21A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lmc DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Escherichia
coli) 		no annotation 4 LEU B  46
TYR B  57
GLU B  59
PRO B  24
 None
 0.88A 2vq5B-2lmcB:
undetectable		 2vq5B-2lmcB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nux 2-KETO-3-DEOXYGLUCON
ATE/2-KETO-3-DEOXY-6
-PHOSPHO GLUCONATE
ALDOLASE

(Sulfolobus
acidocaldarius) 		PF00701
(DHDPS) 		4 LEU A 225
LEU A 279
LEU A 286
GLU A 285
 None
 0.90A 2vq5B-2nuxA:
undetectable		 2vq5B-2nuxA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nyf NOSTOC PUNCTIFORME
PHENYLALANINE
AMMONIA LYASE

(Nostoc
punctiforme) 		PF00221
(Lyase_aromatic) 		4 LEU A 108
LEU A 104
PHE A 107
GLU A 448
 None
 0.86A 2vq5B-2nyfA:
undetectable		 2vq5B-2nyfA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2of3 ZYG-9

(Caenorhabditis
elegans) 		no annotation 4 LEU A 640
LEU A 644
PHE A 657
LEU A 695
 None
 0.96A 2vq5B-2of3A:
undetectable		 2vq5B-2of3A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ou6 HYPOTHETICAL PROTEIN

(Deinococcus
radiodurans) 		PF04978
(DUF664) 		4 LEU A  36
LEU A  40
PHE A 139
LEU A 147
 None
 0.81A 2vq5B-2ou6A:
undetectable		 2vq5B-2ou6A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oux MAGNESIUM
TRANSPORTER

(Enterococcus
faecalis) 		PF00571
(CBS)
PF03448
(MgtE_N) 		4 LEU A  57
LEU A  53
PHE A  26
LEU A  31
 None
 0.89A 2vq5B-2ouxA:
undetectable		 2vq5B-2ouxA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owo DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 LEU A 538
LEU A 535
PHE A 508
LEU A 528
 None
 0.99A 2vq5B-2owoA:
undetectable		 2vq5B-2owoA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q9u A-TYPE FLAVOPROTEIN

(Giardia
intestinalis) 		no annotation 4 LEU A 136
LEU A 143
PHE A 145
LEU A 128
 None
 0.76A 2vq5B-2q9uA:
undetectable		 2vq5B-2q9uA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN

(Salmonella
enterica) 		PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA) 		4 LEU A 686
LEU A 719
LEU A 726
GLU A 725
 None
 0.96A 2vq5B-2qzaA:
undetectable		 2vq5B-2qzaA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rgi PROTEIN S100-A2

(Homo sapiens) 		PF01023
(S_100) 		4 LEU A  38
LEU A  42
PHE A  45
LEU A  58
 None
 0.74A 2vq5B-2rgiA:
undetectable		 2vq5B-2rgiA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rir DIPICOLINATE
SYNTHASE, A CHAIN

(Bacillus
subtilis) 		PF01262
(AlaDh_PNT_C)
PF16924
(DpaA_N) 		4 LEU A 263
PHE A 251
LEU A 225
PRO A 246
 None
 0.85A 2vq5B-2rirA:
undetectable		 2vq5B-2rirA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vza CELL FILAMENTATION
PROTEIN

(Bartonella
henselae) 		PF02661
(Fic) 		4 LEU A 136
LEU A 139
LEU A 151
GLU A 150
 None
 0.92A 2vq5B-2vzaA:
undetectable		 2vq5B-2vzaA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w57 FERRIC UPTAKE
REGULATION PROTEIN

(Vibrio cholerae) 		PF01475
(FUR) 		4 LEU A  39
LEU A  43
LEU A  59
PRO A  18
 None
 0.82A 2vq5B-2w57A:
undetectable		 2vq5B-2w57A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wfh SLIT HOMOLOG 2
PROTEIN C-PRODUCT

(Homo sapiens) 		PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		5 LEU A 761
LEU A 745
PHE A 766
LEU A 773
GLU A 772
 None
 1.08A 2vq5B-2wfhA:
undetectable		 2vq5B-2wfhA:
26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjz IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
SUBUNIT HISH

(Thermotoga
maritima) 		PF00117
(GATase) 		4 LEU B 173
LEU B 153
PHE B 175
PRO B 133
 None
 0.99A 2vq5B-2wjzB:
undetectable		 2vq5B-2wjzB:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wp8 EXOSOME COMPLEX
EXONUCLEASE DIS3

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF13638
(PIN_4)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		4 LEU J 286
LEU J 334
PHE J 285
TYR J 462
 None
None
GOL  J2002 (-4.5A)
None
 0.86A 2vq5B-2wp8J:
undetectable		 2vq5B-2wp8J:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8x TLR1789 PROTEIN

(Thermosynechococcus
elongatus) 		PF07244
(POTRA)
PF08479
(POTRA_2) 		4 LEU X 268
LEU X 271
PHE X 274
LEU X 294
 None
 0.58A 2vq5B-2x8xX:
undetectable		 2vq5B-2x8xX:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xal INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Arabidopsis
thaliana) 		PF06090
(Ins_P5_2-kin) 		4 LEU A 301
LEU A 304
PHE A 218
TYR A 212
 None
 0.99A 2vq5B-2xalA:
undetectable		 2vq5B-2xalA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn1 ALPHA-GALACTOSIDASE

(Lactobacillus
acidophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		5 LEU A 369
LEU A 414
PHE A 412
LEU A 352
GLU A 349
 None
 1.02A 2vq5B-2xn1A:
undetectable		 2vq5B-2xn1A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xs6 PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA

(Homo sapiens) 		PF00620
(RhoGAP) 		4 LEU A 185
LEU A 181
LEU A 214
PRO A 115
 None
None
None
CL  A1295 ( 4.3A)
 0.91A 2vq5B-2xs6A:
undetectable		 2vq5B-2xs6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8v CLASS III CHITINASE,
PUTATIVE

(Aspergillus
fumigatus) 		PF00704
(Glyco_hydro_18) 		4 LEU A 127
LEU A 147
PHE A 155
LEU A 124
 None
 1.00A 2vq5B-2y8vA:
undetectable		 2vq5B-2y8vA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yjg LACTATE RACEMASE
APOPROTEIN

(Thermoanaerobacterium
thermosaccharolyticum) 		PF09861
(DUF2088) 		4 LEU A  86
LEU A  83
LEU A  47
PRO A  78
 None
 0.92A 2vq5B-2yjgA:
undetectable		 2vq5B-2yjgA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus) 		PF00148
(Oxidored_nitro) 		4 LEU C 304
LEU C 283
LEU C 290
PRO C 403
 None
 0.95A 2vq5B-2ynmC:
undetectable		 2vq5B-2ynmC:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywb GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Thermus
thermophilus) 		PF00117
(GATase)
PF00958
(GMP_synt_C) 		4 LEU A  48
LEU A   5
PHE A   7
GLU A  87
 None
 0.65A 2vq5B-2ywbA:
undetectable		 2vq5B-2ywbA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophilus) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 LEU A 389
LEU A 419
LEU A 232
PRO A 422
 None
 0.93A 2vq5B-3a74A:
undetectable		 2vq5B-3a74A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 LEU B 225
LEU B 201
PHE B 203
LEU B 238
 None
 0.66A 2vq5B-3a79B:
undetectable		 2vq5B-3a79B:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ab7 PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0350

(Thermus
thermophilus) 		PF00582
(Usp) 		4 LEU A  23
LEU A  27
LEU A 145
PRO A 176
 LEU  A  23 ( 0.6A)
LEU  A  27 ( 0.6A)
LEU  A 145 ( 0.6A)
PRO  A 176 ( 1.1A)
 0.80A 2vq5B-3ab7A:
undetectable		 2vq5B-3ab7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajb PEROXISOMAL
BIOGENESIS FACTOR 19
PEROXISOMAL
BIOGENESIS FACTOR 3

(Homo sapiens) 		PF04882
(Peroxin-3)
no annotation 		4 LEU B  18
LEU B  21
LEU A 101
GLU A 105
 None
 0.88A 2vq5B-3ajbB:
undetectable		 2vq5B-3ajbB:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3apm PROTEIN-ARGININE
DEIMINASE TYPE-4

(Homo sapiens) 		PF03068
(PAD)
PF08526
(PAD_N)
PF08527
(PAD_M) 		4 LEU A 553
LEU A 557
LEU A 491
PRO A 414
 None
 0.93A 2vq5B-3apmA:
undetectable		 2vq5B-3apmA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b12 FLUOROACETATE
DEHALOGENASE

(Burkholderia
sp.) 		PF00561
(Abhydrolase_1) 		4 LEU A  29
LEU A 100
PHE A  98
LEU A  89
 None
 0.90A 2vq5B-3b12A:
undetectable		 2vq5B-3b12A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2d CD180 ANTIGEN

(Homo sapiens) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 LEU A 305
LEU A 281
PHE A 286
LEU A 313
 None
 0.97A 2vq5B-3b2dA:
undetectable		 2vq5B-3b2dA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3byi RHO GTPASE
ACTIVATING PROTEIN
15

(Homo sapiens) 		PF00620
(RhoGAP) 		4 LEU A 409
LEU A 413
PHE A 410
LEU A 366
 None
 1.00A 2vq5B-3byiA:
undetectable		 2vq5B-3byiA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3m RESPONSE REGULATOR
RECEIVER PROTEIN

(Methanoculleus
marisnigri) 		PF00072
(Response_reg) 		4 LEU A  51
LEU A  82
LEU A  22
PRO A 106
 None
 0.96A 2vq5B-3c3mA:
undetectable		 2vq5B-3c3mA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE

(Burkholderia
pseudomallei) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LEU A 185
PHE A 196
GLU A 233
PRO A 238
 None
 0.91A 2vq5B-3d6bA:
undetectable		 2vq5B-3d6bA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 LEU A 935
LEU A 942
TYR A 874
GLU A 872
 None
 0.97A 2vq5B-3decA:
undetectable		 2vq5B-3decA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfh MANDELATE RACEMASE

(Vibrionales
bacterium
SWAT-3) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 270
LEU A 257
PHE A 261
PRO A 238
 None
 0.97A 2vq5B-3dfhA:
undetectable		 2vq5B-3dfhA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmc NTF2-LIKE PROTEIN

(Trichormus
variabilis) 		PF12680
(SnoaL_2) 		4 LEU A 100
PHE A  99
TYR A  65
GLU A  68
 None
 0.96A 2vq5B-3dmcA:
undetectable		 2vq5B-3dmcA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET

(Escherichia
coli) 		PF07244
(POTRA) 		4 LEU A 226
LEU A 223
PHE A 197
LEU A 193
 None
 0.93A 2vq5B-3efcA:
undetectable		 2vq5B-3efcA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efy CIF (CELL CYCLE
INHIBITING FACTOR)

(Escherichia
coli) 		PF16374
(CIF) 		4 LEU A 141
LEU A 138
LEU A 156
TYR A 167
 None
 0.85A 2vq5B-3efyA:
undetectable		 2vq5B-3efyA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efy CIF (CELL CYCLE
INHIBITING FACTOR)

(Escherichia
coli) 		PF16374
(CIF) 		4 LEU A 141
LEU A 138
PHE A 260
TYR A 167
 None
 0.95A 2vq5B-3efyA:
undetectable		 2vq5B-3efyA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnd CHITINASE

(Bacteroides
thetaiotaomicron) 		PF00704
(Glyco_hydro_18) 		4 LEU A  53
PHE A 325
LEU A  55
PRO A  65
 None
 0.93A 2vq5B-3fndA:
undetectable		 2vq5B-3fndA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM

(Serratia
plymuthica) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 LEU A 296
LEU A 338
PHE A 336
TYR A 509
 None
 0.96A 2vq5B-3gbdA:
undetectable		 2vq5B-3gbdA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gms PUTATIVE
NADPH:QUINONE
REDUCTASE

(Bacillus
thuringiensis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 146
LEU A 170
PHE A 168
LEU A 138
 None
 0.75A 2vq5B-3gmsA:
undetectable		 2vq5B-3gmsA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gz5 MUTT/NUDIX FAMILY
PROTEIN

(Shewanella
oneidensis) 		PF00293
(NUDIX) 		5 LEU A 203
LEU A 222
PHE A 171
LEU A 173
PRO A 163
 None
 1.00A 2vq5B-3gz5A:
undetectable		 2vq5B-3gz5A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd8 XYLANASE INHIBITOR

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 LEU A 168
LEU A 360
PHE A 362
LEU A 145
 None
 0.96A 2vq5B-3hd8A:
undetectable		 2vq5B-3hd8A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hko CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 2
CALMODULIN-LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		4 LEU A 293
LEU A 297
PHE A 277
LEU A 285
 None
 0.95A 2vq5B-3hkoA:
undetectable		 2vq5B-3hkoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hr0 COG4

(Homo sapiens) 		PF04437
(RINT1_TIP1) 		4 LEU A 711
LEU A 715
PHE A 727
LEU A 687
 None
 0.93A 2vq5B-3hr0A:
undetectable		 2vq5B-3hr0A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ht4 ALUMINUM RESISTANCE
PROTEIN

(Bacillus cereus) 		PF06838
(Met_gamma_lyase) 		4 LEU A 100
LEU A 104
PHE A 135
LEU A 121
 None
 0.74A 2vq5B-3ht4A:
undetectable		 2vq5B-3ht4A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2n WD REPEAT-CONTAINING
PROTEIN 92

(Homo sapiens) 		PF00400
(WD40) 		4 LEU A 202
PHE A 195
TYR A 187
PRO A 158
 None
 0.98A 2vq5B-3i2nA:
undetectable		 2vq5B-3i2nA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ian CHITINASE

(Lactococcus
lactis) 		PF00704
(Glyco_hydro_18) 		4 LEU A 318
LEU A 283
LEU A 348
PRO A 298
 None
None
None
EDO  A 362 (-4.1A)
 0.89A 2vq5B-3ianA:
undetectable		 2vq5B-3ianA:
18.84