SIMILAR PATTERNS OF AMINO ACIDS FOR 2VH3_B_DAHB2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1al3 CYS REGULON
TRANSCRIPTIONAL
ACTIVATOR CYSB

(Klebsiella
aerogenes) 		PF03466
(LysR_substrate) 		4 SER A 268
GLY A 203
SER A 245
ALA A 244
 None
 0.78A 2vh3B-1al3A:
0.0		 2vh3B-1al3A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN

(Mastigocladus
laminosus) 		PF00502
(Phycobilisome) 		4 ALA A 126
GLY A  54
SER A 130
ALA A 131
 None
 0.89A 2vh3B-1b33A:
undetectable		 2vh3B-1b33A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cle CHOLESTEROL ESTERASE

([Candida]
cylindracea) 		PF00135
(COesterase) 		4 ALA A 276
GLY A 267
SER A 280
ALA A 281
 None
 0.87A 2vh3B-1cleA:
0.0		 2vh3B-1cleA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e33 ARYLSULFATASE A

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		4 ALA P 314
ALA P 316
GLY P 325
ALA P  53
 None
 0.83A 2vh3B-1e33P:
undetectable		 2vh3B-1e33P:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I ALPHA
SUBUNIT

(Methanopyrus
kandleri) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		4 ALA A 235
ALA A 231
GLY A 111
CYH A 211
 None
 0.84A 2vh3B-1e6vA:
0.0		 2vh3B-1e6vA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebl BETA-KETOACYL-ACP
SYNTHASE III

(Escherichia
coli) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ALA A  79
SER A 139
GLY A  55
ALA A  90
 None
 0.90A 2vh3B-1eblA:
undetectable		 2vh3B-1eblA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eys PHOTOSYNTHETIC
REACTION CENTER

(Thermochromatium
tepidum) 		PF00124
(Photo_RC) 		4 ALA L 248
GLY L 134
SER L 252
ALA L 253
 None
None
BCL  L 602 (-3.2A)
BCL  L 602 ( 4.9A)
 0.79A 2vh3B-1eysL:
0.0		 2vh3B-1eysL:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fui L-FUCOSE ISOMERASE

(Escherichia
coli) 		PF02952
(Fucose_iso_C)
PF07881
(Fucose_iso_N1)
PF07882
(Fucose_iso_N2) 		4 ALA A 126
GLY A 132
SER A 565
ALA A 566
 None
 0.86A 2vh3B-1fuiA:
undetectable		 2vh3B-1fuiA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ghs 1,3-BETA-GLUCANASE

(Hordeum vulgare) 		PF00332
(Glyco_hydro_17) 		4 ALA A  69
ALA A 106
SER A 102
ALA A  64
 None
 0.80A 2vh3B-1ghsA:
undetectable		 2vh3B-1ghsA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg3 TRIOSEPHOSPHATE
ISOMERASE

(Pyrococcus
woesei) 		PF00121
(TIM)
PF05690
(ThiG) 		4 ALA A 183
LYS A  14
SER A 206
ALA A 205
 3PP  A1226 (-4.4A)
3PP  A1226 (-3.3A)
3PP  A1226 (-2.8A)
3PP  A1226 (-3.1A)
 0.76A 2vh3B-1hg3A:
undetectable		 2vh3B-1hg3A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jeq KU70

(Homo sapiens) 		PF02037
(SAP)
PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		4 ALA A  47
SER A 139
GLY A 136
ALA A  44
 None
 0.93A 2vh3B-1jeqA:
0.5		 2vh3B-1jeqA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lam LEUCINE
AMINOPEPTIDASE

(Bos taurus) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 ALA A 123
ALA A 119
GLY A   7
ALA A  92
 None
 0.91A 2vh3B-1lamA:
undetectable		 2vh3B-1lamA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
ALPHA-SUBUNIT

(Pseudomonas
putida) 		PF00676
(E1_dh)
PF12573
(OxoDH_E1alpha_N) 		4 ALA A  44
SER A 271
GLY A 262
ALA A  48
 None
 0.88A 2vh3B-1qs0A:
0.6		 2vh3B-1qs0A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 ALA A 174
ALA A  68
GLY A 110
ALA A  65
 None
 0.89A 2vh3B-1rrhA:
0.1		 2vh3B-1rrhA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sj8 TALIN 1

(Mus musculus) 		PF09141
(Talin_middle) 		4 ALA A 676
ALA A 672
GLY A 740
ALA A 777
 None
 0.92A 2vh3B-1sj8A:
2.3		 2vh3B-1sj8A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 1

(Streptomyces
coelicolor) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 ALA A 107
SER A 353
GLY A 194
ALA A 196
 None
 0.86A 2vh3B-1tqyA:
undetectable		 2vh3B-1tqyA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wd3 ALPHA-L-ARABINOFURAN
OSIDASE B

(Aspergillus
kawachii) 		PF05270
(AbfB)
PF09206
(ArabFuran-catal) 		4 ALA A 496
SER A 380
SER A 389
ALA A 388
 None
 0.91A 2vh3B-1wd3A:
undetectable		 2vh3B-1wd3A:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlh GELATION FACTOR

(Dictyostelium
discoideum) 		PF00630
(Filamin) 		4 ALA A 670
ALA A 721
GLY A 750
ALA A 668
 None
 0.80A 2vh3B-1wlhA:
undetectable		 2vh3B-1wlhA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wwk PHOSPHOGLYCERATE
DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ALA A 281
GLY A 291
SER A  96
ALA A  95
 NAD  A1001 (-4.1A)
None
NAD  A1001 ( 3.9A)
None
 0.85A 2vh3B-1wwkA:
undetectable		 2vh3B-1wwkA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zp6 HYPOTHETICAL PROTEIN
ATU3015

(Agrobacterium
fabrum) 		PF13238
(AAA_18) 		4 ALA A 138
ALA A 119
SER A  20
GLY A  16
 None
None
SO4  A 201 (-3.4A)
None
 0.78A 2vh3B-1zp6A:
undetectable		 2vh3B-1zp6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeq FAB HEAVY CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 ALA H  90
GLY H  42
SER H  93
ALA H  94
 None
 0.90A 2vh3B-2aeqH:
undetectable		 2vh3B-2aeqH:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aw5 NADP-DEPENDENT MALIC
ENZYME

(Homo sapiens) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ALA A 467
ALA A 514
SER A 510
ALA A 462
 None
 0.91A 2vh3B-2aw5A:
undetectable		 2vh3B-2aw5A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bkj FLAVIN REDUCTASE

(Vibrio harveyi) 		PF00881
(Nitroreductase) 		4 ALA A  68
GLY A 126
SER A  72
ALA A  73
 None
 0.87A 2vh3B-2bkjA:
undetectable		 2vh3B-2bkjA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2elc ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Thermus
thermophilus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 ALA A 282
ALA A 284
GLY A 290
ALA A  93
 None
 0.92A 2vh3B-2elcA:
undetectable		 2vh3B-2elcA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fnc MALTOSE ABC
TRANSPORTER,
PERIPLASMIC
MALTOSE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF13416
(SBP_bac_8) 		4 ALA A 114
GLY A 264
SER A 326
ALA A 327
 None
 0.90A 2vh3B-2fncA:
undetectable		 2vh3B-2fncA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ghb MALTOSE ABC
TRANSPORTER,
PERIPLASMIC
MALTOSE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF13416
(SBP_bac_8) 		4 ALA A 114
GLY A 264
SER A 326
ALA A 327
 None
 0.92A 2vh3B-2ghbA:
undetectable		 2vh3B-2ghbA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijz PROBABLE M18-FAMILY
AMINOPEPTIDASE 2

(Pseudomonas
aeruginosa) 		PF02127
(Peptidase_M18) 		4 GLY A 253
SER A 425
ALA A 424
CYH A 257
 None
 0.74A 2vh3B-2ijzA:
undetectable		 2vh3B-2ijzA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7p CELL DIVISION
PROTEIN FTSY

(Thermus
aquaticus) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 ALA D 193
GLY D 163
ALA D 137
CYH D 136
 None
 0.87A 2vh3B-2j7pD:
undetectable		 2vh3B-2j7pD:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mwh ANTI-HIV LECTIN OAA

(Planktothrix
agardhii) 		no annotation 4 ALA A  35
SER A 107
GLY A 111
ALA A  54
 None
 0.88A 2vh3B-2mwhA:
undetectable		 2vh3B-2mwhA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlx XYLULOSE KINASE

(Escherichia
coli) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ALA A 429
ALA A 425
GLY A  75
ALA A 236
 None
 0.83A 2vh3B-2nlxA:
undetectable		 2vh3B-2nlxA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ntj ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH

(Mycobacterium
tuberculosis) 		PF13561
(adh_short_C2) 		4 ALA A  22
ALA A  26
ALA A 239
CYH A 243
 None
 0.93A 2vh3B-2ntjA:
undetectable		 2vh3B-2ntjA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pb9 PHOSPHOMETHYLPYRIMID
INE KINASE

(Pyrococcus
furiosus) 		PF10120
(ThiP_synth) 		4 ALA A 338
ALA A 315
SER A 302
ALA A 343
 None
 0.87A 2vh3B-2pb9A:
undetectable		 2vh3B-2pb9A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uwj TYPE III EXPORT
PROTEIN PSCG

(Pseudomonas
aeruginosa) 		PF09477
(Type_III_YscG) 		4 ALA G  10
SER G  47
GLY G  18
ALA G  25
 None
 0.86A 2vh3B-2uwjG:
undetectable		 2vh3B-2uwjG:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5i SALMONELLA
TYPHIMURIUM DB7155
BACTERIOPHAGE DET7
TAILSPIKE

(unidentified
phage) 		PF09251
(PhageP22-tail) 		4 SER A 481
GLY A 485
SER A 399
ALA A 431
 None
 0.79A 2vh3B-2v5iA:
undetectable		 2vh3B-2v5iA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E1 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF01589
(Alpha_E1_glycop) 		4 ALA A 336
ALA A 359
SER A 309
GLY A 313
 None
 0.91A 2vh3B-2xfbA:
undetectable		 2vh3B-2xfbA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5r BENZALACETONE
SYNTHASE

(Rheum palmatum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 ALA A 333
SER A 184
GLY A  99
ALA A 214
 None
 0.91A 2vh3B-3a5rA:
undetectable		 2vh3B-3a5rA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum) 		PF07940
(Hepar_II_III)
PF16332
(DUF4962) 		4 ALA A 360
SER A 310
SER A 532
ALA A 531
 None
LGU  A1002 ( 2.8A)
None
None
 0.82A 2vh3B-3aflA:
undetectable		 2vh3B-3aflA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 ALA A 409
SER A 413
GLY A 304
ALA A 338
 None
 0.79A 2vh3B-3aqpA:
1.1		 2vh3B-3aqpA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II

(Bartonella
henselae) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 ALA A 287
GLY A 405
SER A 412
ALA A 411
 None
 0.79A 2vh3B-3e60A:
0.2		 2vh3B-3e60A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1v GLUCOKINASE

(Homo sapiens) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 GLY X  72
SER X 453
ALA X 454
CYH X 457
 None
 0.77A 2vh3B-3h1vX:
undetectable		 2vh3B-3h1vX:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3w PHOSPHOGLUCOSAMINE
MUTASE

(Francisella
tularensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 SER A 237
GLY A 216
SER A 204
ALA A 203
 None
 0.89A 2vh3B-3i3wA:
undetectable		 2vh3B-3i3wA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Haemophilus
influenzae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ALA A  79
SER A 139
GLY A  55
ALA A  90
 None
 0.89A 2vh3B-3il3A:
undetectable		 2vh3B-3il3A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3it4 ARGININE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
ARGJ ALPHA CHAIN
ARGININE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
ARGJ BETA CHAIN

(Mycobacterium
tuberculosis) 		PF01960
(ArgJ) 		4 ALA B 209
GLY A  46
SER B 251
ALA B 250
 None
 0.81A 2vh3B-3it4B:
undetectable		 2vh3B-3it4B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsk CYPBP37 PROTEIN

(Neurospora
crassa) 		PF01946
(Thi4) 		4 ALA A 320
SER A 322
GLY A 299
ALA A  94
 None
 0.90A 2vh3B-3jskA:
undetectable		 2vh3B-3jskA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Encephalitozoon
cuniculi) 		PF00274
(Glycolytic) 		4 ALA A 271
SER A 290
GLY A  23
ALA A 326
 None
 0.85A 2vh3B-3mbfA:
undetectable		 2vh3B-3mbfA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nfb BETA-PEPTIDYL
AMINOPEPTIDASE

(Sphingosinicella
xenopeptidilytica) 		PF03576
(Peptidase_S58) 		4 ALA A  17
GLY A 162
SER A 188
ALA A  20
 None
 0.75A 2vh3B-3nfbA:
undetectable		 2vh3B-3nfbA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npe 9-CIS-EPOXYCAROTENOI
D DIOXYGENASE 1,
CHLOROPLASTIC

(Zea mays) 		PF03055
(RPE65) 		4 ALA A 158
ALA A 250
SER A 263
GLY A 246
 None
OH  A   2 ( 4.1A)
None
None
 0.90A 2vh3B-3npeA:
undetectable		 2vh3B-3npeA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3orj SUGAR-BINDING
PROTEIN

(Bacteroides
ovatus) 		no annotation 4 ALA A 397
GLY A 336
SER A 401
ALA A 402
 None
 0.71A 2vh3B-3orjA:
undetectable		 2vh3B-3orjA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pf0 IMELYSIN-LIKE
PROTEIN

(Psychrobacter
arcticus) 		PF09375
(Peptidase_M75) 		4 ALA A 212
GLY A 195
SER A 216
ALA A 217
 None
 0.74A 2vh3B-3pf0A:
1.3		 2vh3B-3pf0A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE

(Chlamydomonas
reinhardtii) 		PF00155
(Aminotran_1_2) 		4 ALA A 284
SER A 281
GLY A 140
LYS A 142
 GOL  A 452 ( 4.0A)
SO4  A 451 (-3.1A)
SO4  A 451 (-3.4A)
SO4  A 451 (-2.7A)
 0.93A 2vh3B-3qguA:
undetectable		 2vh3B-3qguA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3td9 BRANCHED CHAIN AMINO
ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN

(Thermotoga
maritima) 		PF13458
(Peripla_BP_6) 		4 ALA A  94
SER A  98
GLY A  91
ALA A 116
 PHE  A 400 (-4.3A)
None
None
PHE  A 400 (-3.6A)
 0.83A 2vh3B-3td9A:
undetectable		 2vh3B-3td9A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmt PROBABLE FERULOYL
ESTERASE B-1

(Aspergillus
oryzae) 		PF07519
(Tannase) 		4 ALA A 461
ALA A 459
SER A 465
ALA A 466
 None
 0.86A 2vh3B-3wmtA:
undetectable		 2vh3B-3wmtA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP

(Salmonella
enterica) 		PF00814
(Peptidase_M22) 		4 ALA B 266
ALA B 293
SER B 270
ALA B 271
 None
None
None
ADP  B1343 ( 4.1A)
 0.82A 2vh3B-3zeuB:
undetectable		 2vh3B-3zeuB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bz4 COPPER-REPRESSIBLE
POLYPEPTIDE

(Methylomicrobium
album) 		no annotation 4 ALA A 216
ALA A 219
GLY A 209
ALA A  49
 KYN  A  62 ( 3.8A)
None
None
None
 0.85A 2vh3B-4bz4A:
undetectable		 2vh3B-4bz4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzj PROTEIN TRANSPORT
PROTEIN SEC13

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 ALA B 145
GLY B 176
LYS B 183
ALA B 143
 None
 0.83A 2vh3B-4bzjB:
undetectable		 2vh3B-4bzjB:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c23 L-FUCULOSE KINASE
FUCK

(Streptococcus
pneumoniae) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ALA A 429
GLY A 400
SER A 236
ALA A 237
 None
 0.81A 2vh3B-4c23A:
undetectable		 2vh3B-4c23A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		4 ALA A 165
ALA A 169
GLY A 149
ALA A 153
 None
 0.80A 2vh3B-4dryA:
undetectable		 2vh3B-4dryA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emd 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE

(Mycobacteroides
abscessus) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 ALA A 287
GLY A 252
ALA A 181
CYH A 292
 None
 0.88A 2vh3B-4emdA:
undetectable		 2vh3B-4emdA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsj CAPSID PROTEIN BETA

(Flock House
virus) 		PF01829
(Peptidase_A6) 		4 SER A  94
GLY A  83
SER A 170
ALA A 169
 None
 0.79A 2vh3B-4fsjA:
undetectable		 2vh3B-4fsjA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fte CAPSID PROTEIN ALPHA

(Flock House
virus) 		PF01829
(Peptidase_A6) 		4 SER A  94
GLY A  83
SER A 170
ALA A 169
 None
 0.79A 2vh3B-4fteA:
undetectable		 2vh3B-4fteA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzh HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 ALA A 525
ALA A 546
SER A 544
GLY A 489
 None
 0.91A 2vh3B-4fzhA:
undetectable		 2vh3B-4fzhA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6w N-TERMINAL
CYANOBACTIN PROTEASE

(Planktothrix
agardhii) 		PF00082
(Peptidase_S8) 		4 ALA A 253
GLY A 197
SER A 257
ALA A 258
 None
 0.75A 2vh3B-4h6wA:
undetectable		 2vh3B-4h6wA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hds ARSB

(Sporomusa ovata) 		PF02277
(DBI_PRT) 		4 ALA B 128
SER B 131
GLY B 226
ALA B  65
 None
 0.88A 2vh3B-4hdsB:
undetectable		 2vh3B-4hdsB:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy3 PHOSPHOGLYCERATE
OXIDOREDUCTASE

(Rhizobium etli) 		PF02826
(2-Hacid_dh_C) 		4 ALA A 120
ALA A 239
GLY A 286
ALA A 266
 None
 0.85A 2vh3B-4hy3A:
undetectable		 2vh3B-4hy3A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iis BETA-1,3-GLUCANASE
FORM 'RRII GLN 2'

(Hevea
brasiliensis) 		PF00332
(Glyco_hydro_17) 		4 ALA A 148
GLY A 141
SER A 224
ALA A 225
 None
 0.79A 2vh3B-4iisA:
undetectable		 2vh3B-4iisA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqk NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE

(Salmonella
enterica) 		PF02277
(DBI_PRT) 		4 ALA A 183
GLY A 245
SER A 269
ALA A 270
 None
 0.77A 2vh3B-4kqkA:
undetectable		 2vh3B-4kqkA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp2 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CYSB

(Salmonella
enterica) 		PF03466
(LysR_substrate) 		4 SER B 268
GLY B 203
SER B 245
ALA B 244
 None
 0.75A 2vh3B-4lp2B:
undetectable		 2vh3B-4lp2B:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN ALPHA-X
INTEGRIN BETA-2

(Homo sapiens) 		PF00092
(VWA)
PF00362
(Integrin_beta)
PF01839
(FG-GAP)
PF07965
(Integrin_B_tail)
PF08441
(Integrin_alpha2)
PF17205
(PSI_integrin) 		4 ALA A 505
GLY B 249
SER A 442
ALA A 441
 None
 0.84A 2vh3B-4nenA:
undetectable		 2vh3B-4nenA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Geobacter
sulfurreducens) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		4 ALA A 649
ALA A 728
SER A 758
GLY A 736
 None
 0.88A 2vh3B-4nmeA:
undetectable		 2vh3B-4nmeA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlt (3R)-HYDROXYACYL-ACP
DEHYDRATASE SUBUNIT
HADB

(Mycobacterium
tuberculosis) 		PF01575
(MaoC_dehydratas) 		4 ALA B 121
ALA B 135
GLY B  67
ALA B 137
 None
 0.76A 2vh3B-4rltB:
undetectable		 2vh3B-4rltB:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rye D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Mycobacterium
tuberculosis) 		PF00768
(Peptidase_S11) 		4 ALA A 189
ALA A 187
GLY A 228
ALA A 194
 None
 0.88A 2vh3B-4ryeA:
undetectable		 2vh3B-4ryeA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uri CHITINASE-RELATED
AGGLUTININ

(Robinia
pseudoacacia) 		PF00704
(Glyco_hydro_18) 		4 ALA A  47
ALA A  49
GLY A  10
CYH A  28
 None
 0.88A 2vh3B-4uriA:
undetectable		 2vh3B-4uriA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4us4 TRANSPORTER

(Bacillus
halodurans) 		PF00209
(SNF) 		4 ALA A 320
GLY A 109
SER A 324
ALA A 325
 NA  A 701 (-4.1A)
None
NA  A 701 ( 2.4A)
None
 0.89A 2vh3B-4us4A:
1.5		 2vh3B-4us4A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1u LYND

(Lyngbya
aestuarii) 		PF02624
(YcaO) 		4 ALA A 392
GLY A 213
SER A 220
ALA A 219
 None
 0.76A 2vh3B-4v1uA:
undetectable		 2vh3B-4v1uA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyw O-ANTIGEN
BIOSYNTHESIS
GLYCOSYLTRANSFERASE
WBNH

(Escherichia
coli) 		PF00534
(Glycos_transf_1)
PF13439
(Glyco_transf_4) 		4 ALA A 269
GLY A 286
SER A 320
ALA A 319
 None
 0.92A 2vh3B-4xywA:
undetectable		 2vh3B-4xywA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3y BENZOYL-COA
REDUCTASE, PUTATIVE

(Geobacter
metallireducens) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 ALA A  63
GLY A  96
ALA A 100
CYH A  68
 None
MTE  A 702 (-3.0A)
None
None
 0.93A 2vh3B-4z3yA:
undetectable		 2vh3B-4z3yA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF12859
(ANAPC1) 		4 GLY A1473
SER A1483
ALA A1484
CYH A1487
 None
 0.83A 2vh3B-5a31A:
3.1		 2vh3B-5a31A:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnn CAPSID PROTEIN VP1
CAPSID PROTEIN VP3

(Enterovirus D) 		PF00073
(Rhv) 		4 ALA A  28
GLY C 214
SER C 161
CYH C 120
 None
 0.90A 2vh3B-5bnnA:
undetectable		 2vh3B-5bnnA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cef ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Cryptococcus
neoformans) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ALA A 297
ALA A 295
GLY A 289
ALA A 293
 None
 0.92A 2vh3B-5cefA:
undetectable		 2vh3B-5cefA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyl FIMBRIAL SUBUNIT
CUPB6

(Pseudomonas
aeruginosa) 		PF00419
(Fimbrial) 		4 ALA A 330
ALA A 280
GLY A 283
ALA A 333
 None
 0.89A 2vh3B-5cylA:
undetectable		 2vh3B-5cylA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dgq PUTATIVE
ENDOGLUCANASE-RELATE
D PROTEIN

(Photobacterium
profundum) 		PF00759
(Glyco_hydro_9) 		4 ALA A 370
GLY A 561
SER A 456
ALA A 455
 None
 0.91A 2vh3B-5dgqA:
undetectable		 2vh3B-5dgqA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ee4 HPUA

(Kingella
denitrificans) 		PF16960
(HpuA) 		4 ALA A 118
ALA A 140
SER A 149
GLY A  47
 None
 0.87A 2vh3B-5ee4A:
undetectable		 2vh3B-5ee4A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gn5 GLYCEROL KINASE

(Trypanosoma
brucei) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ALA A 454
ALA A 451
GLY A  10
SER A 257
 None
 0.92A 2vh3B-5gn5A:
undetectable		 2vh3B-5gn5A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jfq GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Geoglobus
acetivorans) 		PF00348
(polyprenyl_synt) 		4 ALA A 181
ALA A 185
SER A  52
ALA A  53
 None
 0.88A 2vh3B-5jfqA:
1.4		 2vh3B-5jfqA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT

(Escherichia
coli) 		PF03814
(KdpA) 		4 ALA A 470
SER A 108
SER A 462
ALA A 463
 None
 0.78A 2vh3B-5mrwA:
undetectable		 2vh3B-5mrwA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oar BETA-HEXOSAMINIDASE

(Aspergillus
oryzae) 		no annotation 4 SER B 481
GLY B 449
LYS B 487
SER B 441
 None
 0.82A 2vh3B-5oarB:
undetectable		 2vh3B-5oarB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii) 		no annotation 4 ALA A 355
SER A 157
GLY A 202
ALA A 134
 None
 0.91A 2vh3B-5oc1A:
undetectable		 2vh3B-5oc1A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot0 L-ASPARAGINASE

(Thermococcus
kodakarensis) 		no annotation 4 ALA A  94
SER A  96
GLY A 151
ALA A 295
 None
 0.75A 2vh3B-5ot0A:
undetectable		 2vh3B-5ot0A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue1 5'-METHYLTHIOADENOSI
NE/S-ADENOSYLHOMOCYS
TEINE NUCLEOSIDASE

(Aliivibrio
fischeri) 		PF01048
(PNP_UDP_1) 		4 ALA A  56
ALA A  54
GLY A   7
CYH A  31
 None
 0.84A 2vh3B-5ue1A:
undetectable		 2vh3B-5ue1A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uu6 NADPH-FLAVIN
OXIDOREDUCTASE

(Vibrio
parahaemolyticus) 		PF00881
(Nitroreductase) 		4 ALA A  68
GLY A 126
SER A  72
ALA A  73
 None
 0.89A 2vh3B-5uu6A:
undetectable		 2vh3B-5uu6A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vu2 E1 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		no annotation 4 ALA M 336
ALA M 359
SER M 309
GLY M 313
 None
 0.93A 2vh3B-5vu2M:
undetectable		 2vh3B-5vu2M:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9u THERMOSOME, ALPHA
SUBUNIT

(Carboxydothermus
hydrogenoformans) 		no annotation 4 ALA A 371
ALA A 375
GLY A  86
ALA A 153
 None
 0.92A 2vh3B-5x9uA:
undetectable		 2vh3B-5x9uA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmj FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Desulfovibrio
gigas) 		no annotation 4 ALA A 215
GLY A 381
SER A 395
ALA A 396
 FAD  A 701 (-4.5A)
None
FAD  A 701 ( 4.9A)
None
 0.78A 2vh3B-5xmjA:
undetectable		 2vh3B-5xmjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0m -

(-) 		no annotation 4 ALA A 110
SER A 142
GLY A 117
ALA A 107
 GOL  A1003 (-3.5A)
None
None
None
 0.73A 2vh3B-5y0mA:
undetectable		 2vh3B-5y0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a70 -

(-) 		no annotation 4 ALA B3567
ALA B3571
GLY B3293
CYH B3081
 None
 0.83A 2vh3B-6a70B:
2.1		 2vh3B-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aoo MALATE DEHYDROGENASE

(Haemophilus
influenzae) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ALA A 223
SER A  76
GLY A  13
ALA A 228
 SO4  A 401 (-3.4A)
None
None
None
 0.86A 2vh3B-6aooA:
undetectable		 2vh3B-6aooA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bj9 ACETYL-COA
ACETYLTRANSFERASE A

(Ascaris suum) 		no annotation 4 ALA A 246
ALA A 320
GLY A 289
ALA A 318
 None
 0.87A 2vh3B-6bj9A:
undetectable		 2vh3B-6bj9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6et9 ACETYL-COA
ACETYLTRANSFERASE
THIOLASE

(Methanothermococcus
thermolithotrophicus) 		no annotation 4 ALA A 124
GLY A 377
SER A 127
ALA A 128
 None
 0.92A 2vh3B-6et9A:
undetectable		 2vh3B-6et9A:
24.04