SIMILAR PATTERNS OF AMINO ACIDS FOR 2VDY_A_HCYA1384_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hi2 | EOSINOPHIL-DERIVEDNEUROTOXIN (Homo sapiens) |
PF00074(RnaseA) | 5 | THR A 42ILE A 30ASN A 31PHE A 43HIS A 82 | None | 1.43A | 2vdyA-1hi2A:undetectable | 2vdyA-1hi2A:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js1 | TRANSCARBAMYLASE (Bacteroidesfragilis) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | SER X 140VAL X 109ILE X 126PHE X 130HIS X 133 | None | 1.23A | 2vdyA-1js1X:0.0 | 2vdyA-1js1X:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k38 | BETA-LACTAMASE OXA-2 (Salmonellaenterica) |
PF00905(Transpeptidase) | 5 | SER A 147GLN A 166THR A 68ASN A 143PHE A 69 | None | 1.14A | 2vdyA-1k38A:0.0 | 2vdyA-1k38A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7s | FERRICHROME-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF01497(Peripla_BP_2) | 5 | VAL N 287THR N 181PHE N 274PHE N 238HIS N 240 | None | 1.29A | 2vdyA-1k7sN:undetectable | 2vdyA-1k7sN:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kkh | MEVALONATE KINASE (Methanocaldococcusjannaschii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | SER A 129VAL A 128THR A 44ILE A 102PHE A 100 | None | 1.39A | 2vdyA-1kkhA:0.0 | 2vdyA-1kkhA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyo | HEAVY CHAIN (VH) OFFV-FRAGMENT (Mus musculus) |
PF07686(V-set) | 5 | GLN J 78THR J 21ARG J 98ILE J 29PHE J 79 | None | 1.41A | 2vdyA-1kyoJ:0.5 | 2vdyA-1kyoJ:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ljy | MGP-40 (Capra hircus) |
PF00704(Glyco_hydro_18) | 5 | SER A 181VAL A 157GLN A 172ILE A 170HIS A 176 | None | 1.43A | 2vdyA-1ljyA:undetectable | 2vdyA-1ljyA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oq1 | PROTEIN YESU (Bacillussubtilis) |
PF09224(DUF1961) | 5 | SER A 17VAL A 19GLN A 201ILE A 30PHE A 50 | None | 1.44A | 2vdyA-1oq1A:0.0 | 2vdyA-1oq1A:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pqu | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Haemophilusinfluenzae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | VAL A 154GLN A 279THR A 349PHE A 281ILE A 157 | None | 1.46A | 2vdyA-1pquA:0.0 | 2vdyA-1pquA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8w | GLYCEROL DEHYDRATASE (Clostridiumbutyricum) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | VAL A 563GLN A 494ILE A 461SER A 463PHE A 487 | None | 1.44A | 2vdyA-1r8wA:undetectable | 2vdyA-1r8wA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vzv | VARICELLA-ZOSTERVIRUS PROTEASE (Humanalphaherpesvirus3) |
PF00716(Peptidase_S21) | 5 | SER A 120VAL A 119ILE A 48ASN A 49PHE A 73 | None | 1.41A | 2vdyA-1vzvA:undetectable | 2vdyA-1vzvA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w61 | B-CELL MITOGEN (Trypanosomacruzi) |
PF05544(Pro_racemase) | 5 | VAL A 271GLN A 195ARG A 248ILE A 251ASN A 252 | None | 1.26A | 2vdyA-1w61A:undetectable | 2vdyA-1w61A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xrs | D-LYSINE5,6-AMINOMUTASEALPHA SUBUNIT (Acetoanaerobiumsticklandii) |
PF09043(Lys-AminoMut_A) | 5 | VAL A 179GLN A 401THR A 396ILE A 403ASN A 294 | None | 1.48A | 2vdyA-1xrsA:undetectable | 2vdyA-1xrsA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9f | PUTATIVE MALICENZYME((S)-MALATE:NAD+OXIDOREDUCTASE(DECARBOXYLATING)) (Streptococcuspyogenes) |
PF00390(malic)PF03949(Malic_M) | 5 | SER A 185VAL A 189PHE A 286ILE A 175PHE A 262 | None | 1.07A | 2vdyA-2a9fA:undetectable | 2vdyA-2a9fA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2av9 | THIOESTERASE (Pseudomonasaeruginosa) |
PF03061(4HBT) | 5 | VAL A 31GLN A 16THR A 42ILE A 82PHE A 39 | None | 1.31A | 2vdyA-2av9A:undetectable | 2vdyA-2av9A:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bo9 | HUMAN LATEXIN (Homo sapiens) |
PF06907(Latexin) | 5 | VAL B 58PHE B 89ILE B 21ASN B 22PHE B 91 | None | 1.33A | 2vdyA-2bo9B:undetectable | 2vdyA-2bo9B:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dwz | 26S PROTEASEREGULATORY SUBUNIT6B (Rattusnorvegicus) |
no annotation | 5 | SER B 371THR B 349PHE B 399ILE B 378PHE B 345 | None | 1.46A | 2vdyA-2dwzB:undetectable | 2vdyA-2dwzB:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) |
PF00139(Lectin_legB) | 5 | SER A 201VAL A 57THR A 70PHE A 91ILE A 93 | None | 1.43A | 2vdyA-2e7tA:undetectable | 2vdyA-2e7tA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gf9 | RAS-RELATED PROTEINRAB-3D (Homo sapiens) |
PF00071(Ras) | 5 | VAL A 180ARG A 66ILE A 71SER A 19PHE A 23 | None | 1.42A | 2vdyA-2gf9A:undetectable | 2vdyA-2gf9A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k8q | PROTEIN SHQ1 (Saccharomycescerevisiae) |
no annotation | 5 | SER A 69THR A 3PHE A 42ILE A 74ASN A 75 | None | 1.36A | 2vdyA-2k8qA:undetectable | 2vdyA-2k8qA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvu | MALTOSE BINDINGPROTEIN/NEDD8-ACTIVATING ENZYME E1CATALYTIC SUBUNITCHIMERANEDD8-CONJUGATINGENZYME UBC12 (Homo sapiens) |
PF00179(UQ_con)PF00899(ThiF)PF08825(E2_bind)PF13416(SBP_bac_8) | 5 | SER B2396PHE C 80ILE C 125ASN C 126PHE C 60 | None | 1.39A | 2vdyA-2nvuB:undetectable | 2vdyA-2nvuB:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r0b | SERINE/THREONINE/TYROSINE-INTERACTINGPROTEIN (Homo sapiens) |
PF00782(DSPc) | 5 | THR A 102PHE A 130ILE A 95ASN A 94PHE A 99 | None | 1.28A | 2vdyA-2r0bA:undetectable | 2vdyA-2r0bA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ucz | UBIQUITINCONJUGATING ENZYME (Saccharomycescerevisiae) |
PF00179(UQ_con) | 5 | SER A 122VAL A 123THR A 74ILE A 41PHE A 73 | None | 1.38A | 2vdyA-2uczA:undetectable | 2vdyA-2uczA:18.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 8 | VAL A 17GLN A 224THR A 232PHE A 234ARG A 252ILE A 255PHE A 357TRP A 362 | HCY A1375 ( 4.8A)HCY A1375 (-3.5A)HCY A1375 ( 4.2A)HCY A1375 (-4.8A)HCY A1375 (-4.9A)NoneHCY A1375 ( 4.1A)HCY A1375 (-3.8A) | 0.64A | 2vdyA-2v95A:38.4 | 2vdyA-2v95A:60.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ve3 | PUTATIVE CYTOCHROMEP450 120 (Synechocystissp. PCC 6803) |
PF00067(p450) | 5 | SER A 429THR A 26PHE A 52SER A 83PHE A 29 | REA A1445 ( 4.3A)NoneNoneNoneREA A1445 (-4.6A) | 1.29A | 2vdyA-2ve3A:undetectable | 2vdyA-2ve3A:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsm | HEMAGGLUTININ-NEURAMINIDASE (Nipahhenipavirus) |
PF00423(HN) | 5 | SER A 411VAL A 367THR A 308ILE A 304PHE A 369 | None | 1.20A | 2vdyA-2vsmA:undetectable | 2vdyA-2vsmA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | PHE A 285ILE A 237ASN A 238SER A 241PHE A 281 | None | 1.36A | 2vdyA-2xaxA:undetectable | 2vdyA-2xaxA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | THR A 276PHE A 281ILE A 237ASN A 238PHE A 274 | None | 1.30A | 2vdyA-2xaxA:undetectable | 2vdyA-2xaxA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xf8 | D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | VAL A 172GLN A 220PHE A 221ILE A 158PHE A 225 | None | 1.45A | 2vdyA-2xf8A:undetectable | 2vdyA-2xf8A:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xgy | RELIK CAPSIDN-TERMINAL DOMAIN (Oryctolaguscuniculus) |
PF00607(Gag_p24) | 5 | VAL A 128PHE A 47ILE A 52ASN A 53PHE A 40 | NoneNoneNoneGOL A1138 (-3.7A)None | 1.33A | 2vdyA-2xgyA:undetectable | 2vdyA-2xgyA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yky | BETA-TRANSAMINASE (Mesorhizobiumsp. LUK) |
PF00202(Aminotran_3) | 5 | SER A 287GLN A 331THR A 330ILE A 101HIS A 326 | None | 1.17A | 2vdyA-2ykyA:undetectable | 2vdyA-2ykyA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | VAL A1463PHE A1506ARG A1493ILE A1496ASN A1497 | None | 1.11A | 2vdyA-2zxqA:undetectable | 2vdyA-2zxqA:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afl | OLIGO ALGINATE LYASE (Agrobacteriumfabrum) |
PF07940(Hepar_II_III)PF16332(DUF4962) | 5 | SER A 650GLN A 656THR A 721ILE A 578ASN A 623 | None | 1.32A | 2vdyA-3aflA:undetectable | 2vdyA-3aflA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cia | COLD-ACTIVEAMINOPEPTIDASE (Colwelliapsychrerythraea) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 5 | VAL A 311THR A 266ILE A 307SER A 305PHE A 263 | None | 1.22A | 2vdyA-3ciaA:undetectable | 2vdyA-3ciaA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2y | GTPASE FAMILYPROTEIN (Bacillusanthracis) |
PF01926(MMR_HSR1) | 5 | SER A 362VAL A 334THR A 257ILE A 351PHE A 266 | None | 1.26A | 2vdyA-3h2yA:undetectable | 2vdyA-3h2yA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4s | FTSZ/TUBULIN-RELATEDPROTEIN (Bacillusthuringiensis) |
PF00091(Tubulin) | 5 | VAL A 325PHE A 291ILE A 288PHE A 334TRP A 365 | None | 1.41A | 2vdyA-3j4sA:undetectable | 2vdyA-3j4sA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l1c | KINESIN-14 NCD (Drosophilamelanogaster) |
PF00225(Kinesin) | 5 | SER A 416VAL A 415ILE A 411SER A 406PHE A 644 | None | 1.47A | 2vdyA-3l1cA:undetectable | 2vdyA-3l1cA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m7d | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24) | 5 | VAL A 106THR A 96ARG A 144ILE A 145SER A 227 | None | 1.47A | 2vdyA-3m7dA:undetectable | 2vdyA-3m7dA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pmo | UDP-3-O-[3-HYDROXYMYRISTOYL] GLUCOSAMINEN-ACYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00132(Hexapep)PF04613(LpxD) | 5 | SER A 177VAL A 161ILE A 139SER A 120TRP A 156 | None | 1.44A | 2vdyA-3pmoA:undetectable | 2vdyA-3pmoA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnb | OXACILLINASE (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | SER A 147GLN A 166THR A 68ASN A 143PHE A 69 | None | 1.25A | 2vdyA-3qnbA:undetectable | 2vdyA-3qnbA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qxf | ENDOGLUCANASE (Escherichiacoli) |
PF01270(Glyco_hydro_8) | 5 | SER A 115VAL A 119GLN A 189THR A 192PHE A 191 | None | 1.31A | 2vdyA-3qxfA:undetectable | 2vdyA-3qxfA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6q | CD180 ANTIGEN (Mus musculus) |
PF13855(LRR_8) | 5 | SER A 535GLN A 493ILE A 486ASN A 485PHE A 516 | None | 1.39A | 2vdyA-3t6qA:undetectable | 2vdyA-3t6qA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti2 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Vibrio cholerae) |
PF00275(EPSP_synthase) | 5 | SER A 23VAL A 24THR A 39ARG A 27PHE A 238 | NoneNoneNone CL A 1 ( 3.0A)None | 1.37A | 2vdyA-3ti2A:undetectable | 2vdyA-3ti2A:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u43 | COLICIN-E2 (Escherichiacoli) |
no annotation | 5 | SER B 30PHE B 50ARG B 120ILE B 119ASN B 118 | None | 1.30A | 2vdyA-3u43B:undetectable | 2vdyA-3u43B:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4c | ALDEHYDEDEHYDROGENASE(NADP+) (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 5 | PHE A 237ARG A 220SER A 240PHE A 153HIS A 184 | None | 1.46A | 2vdyA-3v4cA:undetectable | 2vdyA-3v4cA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v7b | UNCHARACTERIZEDPROTEIN (Corynebacteriumdiphtheriae) |
PF09449(DUF2020) | 5 | SER A 102VAL A 116THR A 52ILE A 143HIS A 72 | None | 1.24A | 2vdyA-3v7bA:undetectable | 2vdyA-3v7bA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a22 | FRUCTOSE-BISPHOSPHATE ALDOLASE (Mycobacteriumtuberculosis) |
PF01116(F_bP_aldolase) | 5 | SER A 31VAL A 34THR A 94PHE A 125PHE A 52 | NoneNone NA A1347 (-3.6A)NoneNone | 1.35A | 2vdyA-4a22A:undetectable | 2vdyA-4a22A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2y | EOSINOPHIL CATIONICPROTEIN (Homo sapiens) |
PF00074(RnaseA) | 5 | THR A 42ILE A 30ASN A 31PHE A 43HIS A 82 | None | 1.47A | 2vdyA-4a2yA:undetectable | 2vdyA-4a2yA:14.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | GLN A 232PHE A 242ASN A 264SER A 267HIS A 368 | None | 1.17A | 2vdyA-4c41A:56.7 | 2vdyA-4c41A:96.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | GLN A 232THR A 240PHE A 242ASN A 264SER A 267 | None | 0.85A | 2vdyA-4c41A:56.7 | 2vdyA-4c41A:96.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | SER A 19VAL A 22GLN A 232ARG A 260PHE A 366 | None | 1.10A | 2vdyA-4c41A:56.7 | 2vdyA-4c41A:96.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 7 | VAL A 22GLN A 232PHE A 242ILE A 263ASN A 264PHE A 366HIS A 368 | None | 0.96A | 2vdyA-4c41A:56.7 | 2vdyA-4c41A:96.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 7 | VAL A 22GLN A 232THR A 240PHE A 242ARG A 260ILE A 263PHE A 366 | None | 1.13A | 2vdyA-4c41A:56.7 | 2vdyA-4c41A:96.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 7 | VAL A 22GLN A 232THR A 240PHE A 242ILE A 263ASN A 264PHE A 366 | None | 0.67A | 2vdyA-4c41A:56.7 | 2vdyA-4c41A:96.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6w | CLBP PEPTIDASE (Escherichiacoli) |
PF00144(Beta-lactamase) | 5 | GLN A 70PHE A 72ARG A 50ILE A 47SER A 44 | None | 1.47A | 2vdyA-4e6wA:undetectable | 2vdyA-4e6wA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e93 | TYROSINE-PROTEINKINASE FES/FPS (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | SER A 494VAL A 495GLN A 535THR A 533HIS A 529 | None | 1.22A | 2vdyA-4e93A:undetectable | 2vdyA-4e93A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfj | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 5 | VAL A 106THR A 96ARG A 144ILE A 145SER A 227 | NoneNoneGOL A 703 ( 4.5A)NoneNone | 1.44A | 2vdyA-4gfjA:undetectable | 2vdyA-4gfjA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gn2 | OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 5 | SER A 144GLN A 169THR A 64ASN A 140PHE A 65 | None | 1.25A | 2vdyA-4gn2A:undetectable | 2vdyA-4gn2A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1y | SALIVARY NITROPHORIN (Cimexlectularius) |
no annotation | 5 | SER A 157THR A 11PHE A 278ILE A 255PHE A 167 | None | 1.43A | 2vdyA-4l1yA:undetectable | 2vdyA-4l1yA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmh | EXTRACELLULAR IRONOXIDE RESPIRATORYSYSTEM SURFACEDECAHEME CYTOCHROMEC COMPONENT OMCA (Shewanellaoneidensis) |
no annotation | 5 | SER A 402VAL A 415PHE A 465ILE A 484SER A 486 | None | 1.41A | 2vdyA-4lmhA:undetectable | 2vdyA-4lmhA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mll | BETA-LACTAMASE OXA-1 (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | SER A 147GLN A 172THR A 68ASN A 143PHE A 69 | None | 1.27A | 2vdyA-4mllA:undetectable | 2vdyA-4mllA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn8 | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | THR A 603ILE A 606ASN A 609SER A 607PHE A 604 | None | 1.41A | 2vdyA-4mn8A:undetectable | 2vdyA-4mn8A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mna | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | THR A 603ILE A 606ASN A 609SER A 607PHE A 604 | NoneNoneNoneNAG A 902 (-2.9A)None | 1.46A | 2vdyA-4mnaA:undetectable | 2vdyA-4mnaA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnd | CTPL-MYO-INOSITOL-1-PHOSPHATECYTIDYLYLTRANSFERASE/CDP-L-MYO-INOSITOLMYO-INOSITOLPHOSPHOTRANSFERASE (Archaeoglobusfulgidus) |
PF01066(CDP-OH_P_transf)PF12804(NTP_transf_3) | 5 | THR A 227ARG A 184ILE A 179SER A 175PHE A 229 | None | 1.34A | 2vdyA-4mndA:undetectable | 2vdyA-4mndA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mt1 | DRUG EFFLUX PROTEIN (Neisseriagonorrhoeae) |
PF00873(ACR_tran) | 5 | SER A1025VAL A1026PHE A 517ILE A 983PHE A 979 | None | 1.43A | 2vdyA-4mt1A:undetectable | 2vdyA-4mt1A:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nen | INTEGRIN ALPHA-X (Homo sapiens) |
PF00092(VWA)PF01839(FG-GAP)PF08441(Integrin_alpha2) | 5 | SER A 767VAL A 786THR A 842PHE A 802HIS A 804 | None | 1.35A | 2vdyA-4nenA:undetectable | 2vdyA-4nenA:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfb | C4-DICARBOXYLATE-BINDING PROTEIN (Fusobacteriumnucleatum) |
PF03480(DctP) | 5 | VAL A 29GLN A 251ILE A 50ASN A 51SER A 54 | None | 1.22A | 2vdyA-4pfbA:undetectable | 2vdyA-4pfbA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4roa | SERPIN 2 (Anophelesgambiae) |
PF00079(Serpin) | 5 | SER A 305PHE A 125ILE A 163ASN A 164HIS A 170 | None | 1.36A | 2vdyA-4roaA:39.6 | 2vdyA-4roaA:27.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3l | MAJOR PILIN PROTEIN (Streptococcuspneumoniae) |
no annotation | 5 | SER A 337PHE A 305ILE A 244ASN A 371PHE A 261 | None | 1.37A | 2vdyA-4s3lA:undetectable | 2vdyA-4s3lA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tuf | MAJOR EXTRACELLULARENDOGLUCANASE (Xanthomonascampestris) |
PF00150(Cellulase) | 5 | VAL A 120THR A 54SER A 99PHE A 52HIS A 60 | None | 1.32A | 2vdyA-4tufA:undetectable | 2vdyA-4tufA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bu6 | BPSB (PGAB),POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINEN-DEACETYLASE (Bordetellabronchiseptica) |
PF01522(Polysacc_deac_1) | 5 | SER A 47THR A 42ARG A 290ILE A 288PHE A 43 | NoneNoneSCN A 404 (-4.1A)NoneNone | 1.15A | 2vdyA-5bu6A:undetectable | 2vdyA-5bu6A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5but | KTR SYSTEM POTASSIUMUPTAKE PROTEIN B (Bacillussubtilis) |
PF02386(TrkH) | 5 | SER I 187PHE I 202ILE I 198ASN I 195PHE I 281 | None | 1.36A | 2vdyA-5butI:undetectable | 2vdyA-5butI:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ctm | BETA-LACTAMASE (Bacilluspumilus) |
PF00905(Transpeptidase) | 5 | SER A 181GLN A 200THR A 102ASN A 177PHE A 103 | None | 1.28A | 2vdyA-5ctmA:undetectable | 2vdyA-5ctmA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d2n | C25 BETA (Homo sapiens) |
no annotation | 5 | SER F 7GLN F 54THR F 47PHE F 49ARG F 22 | None | 1.02A | 2vdyA-5d2nF:undetectable | 2vdyA-5d2nF:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d5t | UNCHARACTERIZEDPROTEIN MJ0489 (Methanocaldococcusjannaschii) |
PF06690(DUF1188) | 5 | SER A 263VAL A 265THR A 159PHE A 136ILE A 137 | None | 1.38A | 2vdyA-5d5tA:undetectable | 2vdyA-5d5tA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE BASICPROTEIN 2 (Influenza Cvirus) |
PF00604(Flu_PB2) | 5 | SER C 317VAL C 320THR C 295ARG C 267ILE C 266 | None | 1.33A | 2vdyA-5d9aC:undetectable | 2vdyA-5d9aC:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e13 | NON-SECRETORYRIBONUCLEASE (Homo sapiens) |
PF00074(RnaseA) | 5 | THR A 42ILE A 30ASN A 31PHE A 43HIS A 82 | None | 1.44A | 2vdyA-5e13A:undetectable | 2vdyA-5e13A:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e2f | BETA-LACTAMASE YBXI (Bacillussubtilis) |
PF00905(Transpeptidase) | 5 | SER A 156GLN A 175THR A 77ASN A 152PHE A 78 | None | 1.35A | 2vdyA-5e2fA:undetectable | 2vdyA-5e2fA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqv | BIFUNCTIONAL2',3'-CYCLICNUCLEOTIDE2'-PHOSPHODIESTERASE/3'-NUCLEOTIDASEPERIPLASMICPRECURSOR PROTEIN (Yersinia pestis) |
PF00149(Metallophos) | 5 | VAL A 150ILE A 122ASN A 121PHE A 127HIS A 125 | NoneNoneNoneNonePO4 A 405 ( 3.9A) | 1.26A | 2vdyA-5eqvA:undetectable | 2vdyA-5eqvA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erd | DESMOGLEIN-2 (Homo sapiens) |
PF00028(Cadherin) | 5 | SER A 148GLN A 112PHE A 115ILE A 132PHE A 110 | None | 1.32A | 2vdyA-5erdA:undetectable | 2vdyA-5erdA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fse | UREASE SUBUNIT ALPHA (Sporosarcinapasteurii) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | SER C 496THR C 136ILE C 420PHE C 158HIS C 272 | None | 1.47A | 2vdyA-5fseC:undetectable | 2vdyA-5fseC:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fub | PROTEIN ARGININEMETHYLTRANSFERASE 2 (Danio rerio) |
PF13649(Methyltransf_25) | 5 | VAL A 187GLN A 105ILE A 107ASN A 110SER A 109 | None | 1.34A | 2vdyA-5fubA:undetectable | 2vdyA-5fubA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hm5 | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 5 | VAL A 106THR A 96ARG A 144ILE A 145SER A 227 | None | 1.42A | 2vdyA-5hm5A:undetectable | 2vdyA-5hm5A:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i70 | PLASMEPSIN IV (Plasmodiumfalciparum) |
no annotation | 5 | VAL B 213THR B 183ILE B 195SER B 261PHE B 322 | None | 1.46A | 2vdyA-5i70B:undetectable | 2vdyA-5i70B:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idu | ACYL-COADEHYDROGENASE DOMAINPROTEIN (Paraburkholderiaphymatum) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | SER A 127VAL A 126GLN A 233ILE A 110PHE A 177 | None | 1.25A | 2vdyA-5iduA:undetectable | 2vdyA-5iduA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j72 | PUTATIVEN-ACETYLMURAMOYL-L-ALANINEAMIDASE,AUTOLYSINCWP6 (Clostridioidesdifficile) |
PF01520(Amidase_3)PF04122(CW_binding_2) | 5 | VAL A 424THR A 403ILE A 436ASN A 437SER A 434 | None | 1.20A | 2vdyA-5j72A:undetectable | 2vdyA-5j72A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l16 | PUTATIVESELENOPHOSPHATESYNTHETASE (Leishmaniamajor) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | SER A 123VAL A 122THR A 27ILE A 58SER A 55 | None | 1.41A | 2vdyA-5l16A:undetectable | 2vdyA-5l16A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lq6 | VIRULENCE PROTEINVSDE (Salmonellaenterica) |
PF05563(SpvD) | 5 | ILE A 146ASN A 165SER A 144PHE A 113HIS A 85 | None | 1.33A | 2vdyA-5lq6A:undetectable | 2vdyA-5lq6A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5omm | CAPSID PROTEIN (Norwalk virus) |
PF08435(Calici_coat_C) | 5 | SER A 387VAL A 386ARG A 356ILE A 338PHE A 378 | EDO A 603 (-3.9A)NoneNoneNoneNone | 1.47A | 2vdyA-5ommA:undetectable | 2vdyA-5ommA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ooo | NON-STRUCTURALPROTEIN NS-S (Rift Valleyfeverphlebovirus) |
PF11073(NSs) | 5 | SER A 213VAL A 217GLN A 87ILE A 93SER A 127 | None | 1.48A | 2vdyA-5oooA:undetectable | 2vdyA-5oooA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t9p | RIBOSOME BIOGENESISPROTEIN 15 (Saccharomycescerevisiae) |
no annotation | 5 | SER B 96VAL B 95GLN B 113PHE B 114PHE B 111 | CL B 206 ( 4.6A)NoneNoneNoneNone | 1.33A | 2vdyA-5t9pB:undetectable | 2vdyA-5t9pB:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wde | KINESIN-LIKE PROTEINKIFC3 (Homo sapiens) |
PF00225(Kinesin) | 5 | SER A 746VAL A 452ILE A 479SER A 489PHE A 471 | NoneNoneNoneUNX A 920 ( 4.4A)None | 1.33A | 2vdyA-5wdeA:undetectable | 2vdyA-5wdeA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wt7 | PERIOSTIN (Homo sapiens) |
no annotation | 5 | VAL A 112GLN A 97ILE A 101SER A 99PHE A 42 | None | 1.41A | 2vdyA-5wt7A:undetectable | 2vdyA-5wt7A:13.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wwp | ORF1AB (Middle Eastrespiratorysyndrome-relatedcoronavirus) |
no annotation | 5 | VAL B 280PHE B 269SER B 264PHE B 291HIS B 290 | None | 1.24A | 2vdyA-5wwpB:undetectable | 2vdyA-5wwpB:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yh5 | NICKEL ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Staphylococcusaureus) |
no annotation | 5 | SER A 261VAL A 268PHE A 372ARG A 274ILE A 277 | None | 1.20A | 2vdyA-5yh5A:undetectable | 2vdyA-5yh5A:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5znn | SORTILIN (Mus musculus) |
no annotation | 5 | SER A 478VAL A 486ILE A 413SER A 415HIS A 461 | None | 1.23A | 2vdyA-5znnA:undetectable | 2vdyA-5znnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bf6 | INSULIN-DEGRADINGENZYME (Homo sapiens) |
no annotation | 5 | GLN A 770PHE A1005ARG A 839ILE A 843HIS A 952 | None | 1.32A | 2vdyA-6bf6A:undetectable | 2vdyA-6bf6A:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bqw | BACTERIAL ACTIN ALFA (Bacillussubtilis) |
no annotation | 5 | SER A 189VAL A 176ILE A 215ASN A 214PHE A 208 | None | 1.29A | 2vdyA-6bqwA:undetectable | 2vdyA-6bqwA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6etz | BETA-GALACTOSIDASE (Arthrobactersp. 32cB) |
no annotation | 5 | SER A 59THR A 168ILE A 214PHE A 149HIS A 175 | ACT A1104 (-4.6A)NoneNoneNoneNone | 1.43A | 2vdyA-6etzA:undetectable | 2vdyA-6etzA:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fyh | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
no annotation | 5 | SER A 315VAL A 317THR A 277ILE A 268PHE A 322 | None | 1.39A | 2vdyA-6fyhA:undetectable | 2vdyA-6fyhA:12.64 |