SIMILAR PATTERNS OF AMINO ACIDS FOR 2VDY_A_HCYA1384_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hi2 EOSINOPHIL-DERIVED
NEUROTOXIN


(Homo sapiens)
PF00074
(RnaseA)
5 THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.43A 2vdyA-1hi2A:
undetectable
2vdyA-1hi2A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js1 TRANSCARBAMYLASE

(Bacteroides
fragilis)
PF00185
(OTCace)
PF02729
(OTCace_N)
5 SER X 140
VAL X 109
ILE X 126
PHE X 130
HIS X 133
None
1.23A 2vdyA-1js1X:
0.0
2vdyA-1js1X:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k38 BETA-LACTAMASE OXA-2

(Salmonella
enterica)
PF00905
(Transpeptidase)
5 SER A 147
GLN A 166
THR A  68
ASN A 143
PHE A  69
None
1.14A 2vdyA-1k38A:
0.0
2vdyA-1k38A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN


(Escherichia
coli)
PF01497
(Peripla_BP_2)
5 VAL N 287
THR N 181
PHE N 274
PHE N 238
HIS N 240
None
1.29A 2vdyA-1k7sN:
undetectable
2vdyA-1k7sN:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkh MEVALONATE KINASE

(Methanocaldococcus
jannaschii)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
5 SER A 129
VAL A 128
THR A  44
ILE A 102
PHE A 100
None
1.39A 2vdyA-1kkhA:
0.0
2vdyA-1kkhA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kyo HEAVY CHAIN (VH) OF
FV-FRAGMENT


(Mus musculus)
PF07686
(V-set)
5 GLN J  78
THR J  21
ARG J  98
ILE J  29
PHE J  79
None
1.41A 2vdyA-1kyoJ:
0.5
2vdyA-1kyoJ:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ljy MGP-40

(Capra hircus)
PF00704
(Glyco_hydro_18)
5 SER A 181
VAL A 157
GLN A 172
ILE A 170
HIS A 176
None
1.43A 2vdyA-1ljyA:
undetectable
2vdyA-1ljyA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oq1 PROTEIN YESU

(Bacillus
subtilis)
PF09224
(DUF1961)
5 SER A  17
VAL A  19
GLN A 201
ILE A  30
PHE A  50
None
1.44A 2vdyA-1oq1A:
0.0
2vdyA-1oq1A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pqu ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE


(Haemophilus
influenzae)
PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC)
5 VAL A 154
GLN A 279
THR A 349
PHE A 281
ILE A 157
None
1.46A 2vdyA-1pquA:
0.0
2vdyA-1pquA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum)
PF01228
(Gly_radical)
PF02901
(PFL-like)
5 VAL A 563
GLN A 494
ILE A 461
SER A 463
PHE A 487
None
1.44A 2vdyA-1r8wA:
undetectable
2vdyA-1r8wA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzv VARICELLA-ZOSTER
VIRUS PROTEASE


(Human
alphaherpesvirus
3)
PF00716
(Peptidase_S21)
5 SER A 120
VAL A 119
ILE A  48
ASN A  49
PHE A  73
None
1.41A 2vdyA-1vzvA:
undetectable
2vdyA-1vzvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w61 B-CELL MITOGEN

(Trypanosoma
cruzi)
PF05544
(Pro_racemase)
5 VAL A 271
GLN A 195
ARG A 248
ILE A 251
ASN A 252
None
1.26A 2vdyA-1w61A:
undetectable
2vdyA-1w61A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT


(Acetoanaerobium
sticklandii)
PF09043
(Lys-AminoMut_A)
5 VAL A 179
GLN A 401
THR A 396
ILE A 403
ASN A 294
None
1.48A 2vdyA-1xrsA:
undetectable
2vdyA-1xrsA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9f PUTATIVE MALIC
ENZYME
((S)-MALATE:NAD+
OXIDOREDUCTASE
(DECARBOXYLATING))


(Streptococcus
pyogenes)
PF00390
(malic)
PF03949
(Malic_M)
5 SER A 185
VAL A 189
PHE A 286
ILE A 175
PHE A 262
None
1.07A 2vdyA-2a9fA:
undetectable
2vdyA-2a9fA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2av9 THIOESTERASE

(Pseudomonas
aeruginosa)
PF03061
(4HBT)
5 VAL A  31
GLN A  16
THR A  42
ILE A  82
PHE A  39
None
1.31A 2vdyA-2av9A:
undetectable
2vdyA-2av9A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bo9 HUMAN LATEXIN

(Homo sapiens)
PF06907
(Latexin)
5 VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
None
1.33A 2vdyA-2bo9B:
undetectable
2vdyA-2bo9B:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwz 26S PROTEASE
REGULATORY SUBUNIT
6B


(Rattus
norvegicus)
no annotation 5 SER B 371
THR B 349
PHE B 399
ILE B 378
PHE B 345
None
1.46A 2vdyA-2dwzB:
undetectable
2vdyA-2dwzB:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7t BASIC AGGLUTININ

(Psophocarpus
tetragonolobus)
PF00139
(Lectin_legB)
5 SER A 201
VAL A  57
THR A  70
PHE A  91
ILE A  93
None
1.43A 2vdyA-2e7tA:
undetectable
2vdyA-2e7tA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf9 RAS-RELATED PROTEIN
RAB-3D


(Homo sapiens)
PF00071
(Ras)
5 VAL A 180
ARG A  66
ILE A  71
SER A  19
PHE A  23
None
1.42A 2vdyA-2gf9A:
undetectable
2vdyA-2gf9A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k8q PROTEIN SHQ1

(Saccharomyces
cerevisiae)
no annotation 5 SER A  69
THR A   3
PHE A  42
ILE A  74
ASN A  75
None
1.36A 2vdyA-2k8qA:
undetectable
2vdyA-2k8qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12


(Homo sapiens)
PF00179
(UQ_con)
PF00899
(ThiF)
PF08825
(E2_bind)
PF13416
(SBP_bac_8)
5 SER B2396
PHE C  80
ILE C 125
ASN C 126
PHE C  60
None
1.39A 2vdyA-2nvuB:
undetectable
2vdyA-2nvuB:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0b SERINE/THREONINE/TYR
OSINE-INTERACTING
PROTEIN


(Homo sapiens)
PF00782
(DSPc)
5 THR A 102
PHE A 130
ILE A  95
ASN A  94
PHE A  99
None
1.28A 2vdyA-2r0bA:
undetectable
2vdyA-2r0bA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ucz UBIQUITIN
CONJUGATING ENZYME


(Saccharomyces
cerevisiae)
PF00179
(UQ_con)
5 SER A 122
VAL A 123
THR A  74
ILE A  41
PHE A  73
None
1.38A 2vdyA-2uczA:
undetectable
2vdyA-2uczA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2v95 CORTICOSTEROID-BINDI
NG GLOBULIN


(Rattus
norvegicus)
PF00079
(Serpin)
8 VAL A  17
GLN A 224
THR A 232
PHE A 234
ARG A 252
ILE A 255
PHE A 357
TRP A 362
HCY  A1375 ( 4.8A)
HCY  A1375 (-3.5A)
HCY  A1375 ( 4.2A)
HCY  A1375 (-4.8A)
HCY  A1375 (-4.9A)
None
HCY  A1375 ( 4.1A)
HCY  A1375 (-3.8A)
0.64A 2vdyA-2v95A:
38.4
2vdyA-2v95A:
60.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ve3 PUTATIVE CYTOCHROME
P450 120


(Synechocystis
sp. PCC 6803)
PF00067
(p450)
5 SER A 429
THR A  26
PHE A  52
SER A  83
PHE A  29
REA  A1445 ( 4.3A)
None
None
None
REA  A1445 (-4.6A)
1.29A 2vdyA-2ve3A:
undetectable
2vdyA-2ve3A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsm HEMAGGLUTININ-NEURAM
INIDASE


(Nipah
henipavirus)
PF00423
(HN)
5 SER A 411
VAL A 367
THR A 308
ILE A 304
PHE A 369
None
1.20A 2vdyA-2vsmA:
undetectable
2vdyA-2vsmA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xax RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
SUBUNIT ALPHA


(Escherichia
coli)
PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone)
5 PHE A 285
ILE A 237
ASN A 238
SER A 241
PHE A 281
None
1.36A 2vdyA-2xaxA:
undetectable
2vdyA-2xaxA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xax RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
SUBUNIT ALPHA


(Escherichia
coli)
PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone)
5 THR A 276
PHE A 281
ILE A 237
ASN A 238
PHE A 274
None
1.30A 2vdyA-2xaxA:
undetectable
2vdyA-2xaxA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf8 D-ERYTHROSE-4-PHOSPH
ATE DEHYDROGENASE


(Escherichia
coli)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
5 VAL A 172
GLN A 220
PHE A 221
ILE A 158
PHE A 225
None
1.45A 2vdyA-2xf8A:
undetectable
2vdyA-2xf8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xgy RELIK CAPSID
N-TERMINAL DOMAIN


(Oryctolagus
cuniculus)
PF00607
(Gag_p24)
5 VAL A 128
PHE A  47
ILE A  52
ASN A  53
PHE A  40
None
None
None
GOL  A1138 (-3.7A)
None
1.33A 2vdyA-2xgyA:
undetectable
2vdyA-2xgyA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yky BETA-TRANSAMINASE

(Mesorhizobium
sp. LUK)
PF00202
(Aminotran_3)
5 SER A 287
GLN A 331
THR A 330
ILE A 101
HIS A 326
None
1.17A 2vdyA-2ykyA:
undetectable
2vdyA-2ykyA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE


(Bifidobacterium
longum)
PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C)
5 VAL A1463
PHE A1506
ARG A1493
ILE A1496
ASN A1497
None
1.11A 2vdyA-2zxqA:
undetectable
2vdyA-2zxqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum)
PF07940
(Hepar_II_III)
PF16332
(DUF4962)
5 SER A 650
GLN A 656
THR A 721
ILE A 578
ASN A 623
None
1.32A 2vdyA-3aflA:
undetectable
2vdyA-3aflA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cia COLD-ACTIVE
AMINOPEPTIDASE


(Colwellia
psychrerythraea)
PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C)
5 VAL A 311
THR A 266
ILE A 307
SER A 305
PHE A 263
None
1.22A 2vdyA-3ciaA:
undetectable
2vdyA-3ciaA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2y GTPASE FAMILY
PROTEIN


(Bacillus
anthracis)
PF01926
(MMR_HSR1)
5 SER A 362
VAL A 334
THR A 257
ILE A 351
PHE A 266
None
1.26A 2vdyA-3h2yA:
undetectable
2vdyA-3h2yA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4s FTSZ/TUBULIN-RELATED
PROTEIN


(Bacillus
thuringiensis)
PF00091
(Tubulin)
5 VAL A 325
PHE A 291
ILE A 288
PHE A 334
TRP A 365
None
1.41A 2vdyA-3j4sA:
undetectable
2vdyA-3j4sA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l1c KINESIN-14 NCD

(Drosophila
melanogaster)
PF00225
(Kinesin)
5 SER A 416
VAL A 415
ILE A 411
SER A 406
PHE A 644
None
1.47A 2vdyA-3l1cA:
undetectable
2vdyA-3l1cA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7d TOPOISOMERASE V

(Methanopyrus
kandleri)
PF13412
(HTH_24)
5 VAL A 106
THR A  96
ARG A 144
ILE A 145
SER A 227
None
1.47A 2vdyA-3m7dA:
undetectable
2vdyA-3m7dA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE


(Pseudomonas
aeruginosa)
PF00132
(Hexapep)
PF04613
(LpxD)
5 SER A 177
VAL A 161
ILE A 139
SER A 120
TRP A 156
None
1.44A 2vdyA-3pmoA:
undetectable
2vdyA-3pmoA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnb OXACILLINASE

(Escherichia
coli)
PF00905
(Transpeptidase)
5 SER A 147
GLN A 166
THR A  68
ASN A 143
PHE A  69
None
1.25A 2vdyA-3qnbA:
undetectable
2vdyA-3qnbA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qxf ENDOGLUCANASE

(Escherichia
coli)
PF01270
(Glyco_hydro_8)
5 SER A 115
VAL A 119
GLN A 189
THR A 192
PHE A 191
None
1.31A 2vdyA-3qxfA:
undetectable
2vdyA-3qxfA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus)
PF13855
(LRR_8)
5 SER A 535
GLN A 493
ILE A 486
ASN A 485
PHE A 516
None
1.39A 2vdyA-3t6qA:
undetectable
2vdyA-3t6qA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti2 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE


(Vibrio cholerae)
PF00275
(EPSP_synthase)
5 SER A  23
VAL A  24
THR A  39
ARG A  27
PHE A 238
None
None
None
CL  A   1 ( 3.0A)
None
1.37A 2vdyA-3ti2A:
undetectable
2vdyA-3ti2A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u43 COLICIN-E2

(Escherichia
coli)
no annotation 5 SER B  30
PHE B  50
ARG B 120
ILE B 119
ASN B 118
None
1.30A 2vdyA-3u43B:
undetectable
2vdyA-3u43B:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4c ALDEHYDE
DEHYDROGENASE
(NADP+)


(Sinorhizobium
meliloti)
PF00171
(Aldedh)
5 PHE A 237
ARG A 220
SER A 240
PHE A 153
HIS A 184
None
1.46A 2vdyA-3v4cA:
undetectable
2vdyA-3v4cA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v7b UNCHARACTERIZED
PROTEIN


(Corynebacterium
diphtheriae)
PF09449
(DUF2020)
5 SER A 102
VAL A 116
THR A  52
ILE A 143
HIS A  72
None
1.24A 2vdyA-3v7bA:
undetectable
2vdyA-3v7bA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a22 FRUCTOSE-BISPHOSPHAT
E ALDOLASE


(Mycobacterium
tuberculosis)
PF01116
(F_bP_aldolase)
5 SER A  31
VAL A  34
THR A  94
PHE A 125
PHE A  52
None
None
NA  A1347 (-3.6A)
None
None
1.35A 2vdyA-4a22A:
undetectable
2vdyA-4a22A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2y EOSINOPHIL CATIONIC
PROTEIN


(Homo sapiens)
PF00074
(RnaseA)
5 THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.47A 2vdyA-4a2yA:
undetectable
2vdyA-4a2yA:
14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN


(Homo sapiens)
PF00079
(Serpin)
5 GLN A 232
PHE A 242
ASN A 264
SER A 267
HIS A 368
None
1.17A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN


(Homo sapiens)
PF00079
(Serpin)
5 GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.85A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN


(Homo sapiens)
PF00079
(Serpin)
5 SER A  19
VAL A  22
GLN A 232
ARG A 260
PHE A 366
None
1.10A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN


(Homo sapiens)
PF00079
(Serpin)
7 VAL A  22
GLN A 232
PHE A 242
ILE A 263
ASN A 264
PHE A 366
HIS A 368
None
0.96A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN


(Homo sapiens)
PF00079
(Serpin)
7 VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.13A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN


(Homo sapiens)
PF00079
(Serpin)
7 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.67A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6w CLBP PEPTIDASE

(Escherichia
coli)
PF00144
(Beta-lactamase)
5 GLN A  70
PHE A  72
ARG A  50
ILE A  47
SER A  44
None
1.47A 2vdyA-4e6wA:
undetectable
2vdyA-4e6wA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e93 TYROSINE-PROTEIN
KINASE FES/FPS


(Homo sapiens)
PF00017
(SH2)
PF07714
(Pkinase_Tyr)
5 SER A 494
VAL A 495
GLN A 535
THR A 533
HIS A 529
None
1.22A 2vdyA-4e93A:
undetectable
2vdyA-4e93A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfj TOPOISOMERASE V

(Methanopyrus
kandleri)
PF13412
(HTH_24)
PF14520
(HHH_5)
5 VAL A 106
THR A  96
ARG A 144
ILE A 145
SER A 227
None
None
GOL  A 703 ( 4.5A)
None
None
1.44A 2vdyA-4gfjA:
undetectable
2vdyA-4gfjA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gn2 OXACILLINASE

(Pseudomonas
aeruginosa)
PF00905
(Transpeptidase)
5 SER A 144
GLN A 169
THR A  64
ASN A 140
PHE A  65
None
1.25A 2vdyA-4gn2A:
undetectable
2vdyA-4gn2A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius)
no annotation 5 SER A 157
THR A  11
PHE A 278
ILE A 255
PHE A 167
None
1.43A 2vdyA-4l1yA:
undetectable
2vdyA-4l1yA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmh EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT OMCA


(Shewanella
oneidensis)
no annotation 5 SER A 402
VAL A 415
PHE A 465
ILE A 484
SER A 486
None
1.41A 2vdyA-4lmhA:
undetectable
2vdyA-4lmhA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mll BETA-LACTAMASE OXA-1

(Escherichia
coli)
PF00905
(Transpeptidase)
5 SER A 147
GLN A 172
THR A  68
ASN A 143
PHE A  69
None
1.27A 2vdyA-4mllA:
undetectable
2vdyA-4mllA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mn8 LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 THR A 603
ILE A 606
ASN A 609
SER A 607
PHE A 604
None
1.41A 2vdyA-4mn8A:
undetectable
2vdyA-4mn8A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mna LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 THR A 603
ILE A 606
ASN A 609
SER A 607
PHE A 604
None
None
None
NAG  A 902 (-2.9A)
None
1.46A 2vdyA-4mnaA:
undetectable
2vdyA-4mnaA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnd CTP
L-MYO-INOSITOL-1-PHO
SPHATE
CYTIDYLYLTRANSFERASE
/CDP-L-MYO-INOSITOL
MYO-INOSITOLPHOSPHOT
RANSFERASE


(Archaeoglobus
fulgidus)
PF01066
(CDP-OH_P_transf)
PF12804
(NTP_transf_3)
5 THR A 227
ARG A 184
ILE A 179
SER A 175
PHE A 229
None
1.34A 2vdyA-4mndA:
undetectable
2vdyA-4mndA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt1 DRUG EFFLUX PROTEIN

(Neisseria
gonorrhoeae)
PF00873
(ACR_tran)
5 SER A1025
VAL A1026
PHE A 517
ILE A 983
PHE A 979
None
1.43A 2vdyA-4mt1A:
undetectable
2vdyA-4mt1A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN ALPHA-X

(Homo sapiens)
PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2)
5 SER A 767
VAL A 786
THR A 842
PHE A 802
HIS A 804
None
1.35A 2vdyA-4nenA:
undetectable
2vdyA-4nenA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfb C4-DICARBOXYLATE-BIN
DING PROTEIN


(Fusobacterium
nucleatum)
PF03480
(DctP)
5 VAL A  29
GLN A 251
ILE A  50
ASN A  51
SER A  54
None
1.22A 2vdyA-4pfbA:
undetectable
2vdyA-4pfbA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4roa SERPIN 2

(Anopheles
gambiae)
PF00079
(Serpin)
5 SER A 305
PHE A 125
ILE A 163
ASN A 164
HIS A 170
None
1.36A 2vdyA-4roaA:
39.6
2vdyA-4roaA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3l MAJOR PILIN PROTEIN

(Streptococcus
pneumoniae)
no annotation 5 SER A 337
PHE A 305
ILE A 244
ASN A 371
PHE A 261
None
1.37A 2vdyA-4s3lA:
undetectable
2vdyA-4s3lA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE


(Xanthomonas
campestris)
PF00150
(Cellulase)
5 VAL A 120
THR A  54
SER A  99
PHE A  52
HIS A  60
None
1.32A 2vdyA-4tufA:
undetectable
2vdyA-4tufA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE


(Bordetella
bronchiseptica)
PF01522
(Polysacc_deac_1)
5 SER A  47
THR A  42
ARG A 290
ILE A 288
PHE A  43
None
None
SCN  A 404 (-4.1A)
None
None
1.15A 2vdyA-5bu6A:
undetectable
2vdyA-5bu6A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5but KTR SYSTEM POTASSIUM
UPTAKE PROTEIN B


(Bacillus
subtilis)
PF02386
(TrkH)
5 SER I 187
PHE I 202
ILE I 198
ASN I 195
PHE I 281
None
1.36A 2vdyA-5butI:
undetectable
2vdyA-5butI:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ctm BETA-LACTAMASE

(Bacillus
pumilus)
PF00905
(Transpeptidase)
5 SER A 181
GLN A 200
THR A 102
ASN A 177
PHE A 103
None
1.28A 2vdyA-5ctmA:
undetectable
2vdyA-5ctmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d2n C25 BETA

(Homo sapiens)
no annotation 5 SER F   7
GLN F  54
THR F  47
PHE F  49
ARG F  22
None
1.02A 2vdyA-5d2nF:
undetectable
2vdyA-5d2nF:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d5t UNCHARACTERIZED
PROTEIN MJ0489


(Methanocaldococcus
jannaschii)
PF06690
(DUF1188)
5 SER A 263
VAL A 265
THR A 159
PHE A 136
ILE A 137
None
1.38A 2vdyA-5d5tA:
undetectable
2vdyA-5d5tA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d9a POLYMERASE BASIC
PROTEIN 2


(Influenza C
virus)
PF00604
(Flu_PB2)
5 SER C 317
VAL C 320
THR C 295
ARG C 267
ILE C 266
None
1.33A 2vdyA-5d9aC:
undetectable
2vdyA-5d9aC:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e13 NON-SECRETORY
RIBONUCLEASE


(Homo sapiens)
PF00074
(RnaseA)
5 THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.44A 2vdyA-5e13A:
undetectable
2vdyA-5e13A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2f BETA-LACTAMASE YBXI

(Bacillus
subtilis)
PF00905
(Transpeptidase)
5 SER A 156
GLN A 175
THR A  77
ASN A 152
PHE A  78
None
1.35A 2vdyA-5e2fA:
undetectable
2vdyA-5e2fA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN


(Yersinia pestis)
PF00149
(Metallophos)
5 VAL A 150
ILE A 122
ASN A 121
PHE A 127
HIS A 125
None
None
None
None
PO4  A 405 ( 3.9A)
1.26A 2vdyA-5eqvA:
undetectable
2vdyA-5eqvA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5erd DESMOGLEIN-2

(Homo sapiens)
PF00028
(Cadherin)
5 SER A 148
GLN A 112
PHE A 115
ILE A 132
PHE A 110
None
1.32A 2vdyA-5erdA:
undetectable
2vdyA-5erdA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fse UREASE SUBUNIT ALPHA

(Sporosarcina
pasteurii)
PF00449
(Urease_alpha)
PF01979
(Amidohydro_1)
5 SER C 496
THR C 136
ILE C 420
PHE C 158
HIS C 272
None
1.47A 2vdyA-5fseC:
undetectable
2vdyA-5fseC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fub PROTEIN ARGININE
METHYLTRANSFERASE 2


(Danio rerio)
PF13649
(Methyltransf_25)
5 VAL A 187
GLN A 105
ILE A 107
ASN A 110
SER A 109
None
1.34A 2vdyA-5fubA:
undetectable
2vdyA-5fubA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm5 TOPOISOMERASE V

(Methanopyrus
kandleri)
PF13412
(HTH_24)
PF14520
(HHH_5)
5 VAL A 106
THR A  96
ARG A 144
ILE A 145
SER A 227
None
1.42A 2vdyA-5hm5A:
undetectable
2vdyA-5hm5A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i70 PLASMEPSIN IV

(Plasmodium
falciparum)
no annotation 5 VAL B 213
THR B 183
ILE B 195
SER B 261
PHE B 322
None
1.46A 2vdyA-5i70B:
undetectable
2vdyA-5i70B:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN


(Paraburkholderia
phymatum)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
5 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
None
1.25A 2vdyA-5iduA:
undetectable
2vdyA-5iduA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j72 PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE
AMIDASE,AUTOLYSIN
CWP6


(Clostridioides
difficile)
PF01520
(Amidase_3)
PF04122
(CW_binding_2)
5 VAL A 424
THR A 403
ILE A 436
ASN A 437
SER A 434
None
1.20A 2vdyA-5j72A:
undetectable
2vdyA-5j72A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l16 PUTATIVE
SELENOPHOSPHATE
SYNTHETASE


(Leishmania
major)
PF00586
(AIRS)
PF02769
(AIRS_C)
5 SER A 123
VAL A 122
THR A  27
ILE A  58
SER A  55
None
1.41A 2vdyA-5l16A:
undetectable
2vdyA-5l16A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lq6 VIRULENCE PROTEIN
VSDE


(Salmonella
enterica)
PF05563
(SpvD)
5 ILE A 146
ASN A 165
SER A 144
PHE A 113
HIS A  85
None
1.33A 2vdyA-5lq6A:
undetectable
2vdyA-5lq6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5omm CAPSID PROTEIN

(Norwalk virus)
PF08435
(Calici_coat_C)
5 SER A 387
VAL A 386
ARG A 356
ILE A 338
PHE A 378
EDO  A 603 (-3.9A)
None
None
None
None
1.47A 2vdyA-5ommA:
undetectable
2vdyA-5ommA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ooo NON-STRUCTURAL
PROTEIN NS-S


(Rift Valley
fever
phlebovirus)
PF11073
(NSs)
5 SER A 213
VAL A 217
GLN A  87
ILE A  93
SER A 127
None
1.48A 2vdyA-5oooA:
undetectable
2vdyA-5oooA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t9p RIBOSOME BIOGENESIS
PROTEIN 15


(Saccharomyces
cerevisiae)
no annotation 5 SER B  96
VAL B  95
GLN B 113
PHE B 114
PHE B 111
CL  B 206 ( 4.6A)
None
None
None
None
1.33A 2vdyA-5t9pB:
undetectable
2vdyA-5t9pB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wde KINESIN-LIKE PROTEIN
KIFC3


(Homo sapiens)
PF00225
(Kinesin)
5 SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
None
None
None
UNX  A 920 ( 4.4A)
None
1.33A 2vdyA-5wdeA:
undetectable
2vdyA-5wdeA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wt7 PERIOSTIN

(Homo sapiens)
no annotation 5 VAL A 112
GLN A  97
ILE A 101
SER A  99
PHE A  42
None
1.41A 2vdyA-5wt7A:
undetectable
2vdyA-5wt7A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wwp ORF1AB

(Middle East
respiratory
syndrome-related
coronavirus)
no annotation 5 VAL B 280
PHE B 269
SER B 264
PHE B 291
HIS B 290
None
1.24A 2vdyA-5wwpB:
undetectable
2vdyA-5wwpB:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh5 NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN


(Staphylococcus
aureus)
no annotation 5 SER A 261
VAL A 268
PHE A 372
ARG A 274
ILE A 277
None
1.20A 2vdyA-5yh5A:
undetectable
2vdyA-5yh5A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5znn SORTILIN

(Mus musculus)
no annotation 5 SER A 478
VAL A 486
ILE A 413
SER A 415
HIS A 461
None
1.23A 2vdyA-5znnA:
undetectable
2vdyA-5znnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bf6 INSULIN-DEGRADING
ENZYME


(Homo sapiens)
no annotation 5 GLN A 770
PHE A1005
ARG A 839
ILE A 843
HIS A 952
None
1.32A 2vdyA-6bf6A:
undetectable
2vdyA-6bf6A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bqw BACTERIAL ACTIN ALFA

(Bacillus
subtilis)
no annotation 5 SER A 189
VAL A 176
ILE A 215
ASN A 214
PHE A 208
None
1.29A 2vdyA-6bqwA:
undetectable
2vdyA-6bqwA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB)
no annotation 5 SER A  59
THR A 168
ILE A 214
PHE A 149
HIS A 175
ACT  A1104 (-4.6A)
None
None
None
None
1.43A 2vdyA-6etzA:
undetectable
2vdyA-6etzA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fyh E3 UBIQUITIN-PROTEIN
LIGASE HUWE1


(Homo sapiens)
no annotation 5 SER A 315
VAL A 317
THR A 277
ILE A 268
PHE A 322
None
1.39A 2vdyA-6fyhA:
undetectable
2vdyA-6fyhA:
12.64