SIMILAR PATTERNS OF AMINO ACIDS FOR 2VCV_G_ASDG1224_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aw1 TRIOSEPHOSPHATE
ISOMERASE

(Moritella
marina) 		PF00121
(TIM) 		4 PRO A 217
ALA A 237
ALA A 232
PHE A 224
 None
 0.88A 2vcvG-1aw1A:
0.0		 2vcvG-1aw1A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cnv CONCANAVALIN B

(Canavalia
ensiformis) 		PF00704
(Glyco_hydro_18) 		4 LEU A  83
LEU A 172
ALA A 175
PHE A 181
 None
 0.90A 2vcvG-1cnvA:
0.0		 2vcvG-1cnvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dci DIENOYL-COA
ISOMERASE

(Rattus
norvegicus) 		PF00378
(ECH_1) 		4 LEU A  88
ALA A 180
ALA A 164
PHE A 113
 None
 1.00A 2vcvG-1dciA:
0.0		 2vcvG-1dciA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkd GROEL

(Escherichia
coli) 		PF00118
(Cpn60_TCP1) 		4 LEU A 221
ALA A 275
LEU A 262
ALA A 258
 None
 1.00A 2vcvG-1dkdA:
0.0		 2vcvG-1dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dub 2-ENOYL-COA
HYDRATASE

(Rattus
norvegicus) 		PF00378
(ECH_1) 		4 PHE A 160
LEU A 218
ALA A 132
ALA A 138
 None
 1.01A 2vcvG-1dubA:
0.0		 2vcvG-1dubA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ejf PROGESTERONE
RECEPTOR P23

(Homo sapiens) 		PF04969
(CS) 		4 PHE A  19
LEU A  55
LEU A  99
ALA A   6
 None
 1.02A 2vcvG-1ejfA:
0.0		 2vcvG-1ejfA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fkm PROTEIN (GYP1P)

(Saccharomyces
cerevisiae) 		PF00566
(RabGAP-TBC) 		4 LEU A 488
LEU A 619
ALA A 622
PHE A 574
 None
 1.00A 2vcvG-1fkmA:
1.5		 2vcvG-1fkmA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gxs P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A

(Sorghum bicolor) 		PF00450
(Peptidase_S10) 		4 LEU A  13
PRO A  17
LEU A  91
PHE A  22
 None
 0.85A 2vcvG-1gxsA:
0.1		 2vcvG-1gxsA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyn BAND 3 ANION
TRANSPORT PROTEIN

(Homo sapiens) 		PF07565
(Band_3_cyto) 		4 PHE P 236
LEU P 136
ALA P 156
ALA P 234
 None
 1.02A 2vcvG-1hynP:
0.0		 2vcvG-1hynP:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kr1 HEVAMINE A

(Hevea
brasiliensis) 		PF00704
(Glyco_hydro_18) 		4 LEU A  78
LEU A 166
ALA A 169
PHE A 175
 None
 0.97A 2vcvG-1kr1A:
undetectable		 2vcvG-1kr1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la1 GROEL

(Escherichia
coli) 		PF00118
(Cpn60_TCP1) 		4 LEU A 221
ALA A 275
LEU A 262
ALA A 258
 None
 0.89A 2vcvG-1la1A:
undetectable		 2vcvG-1la1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mdf 2,3-DIHYDROXYBENZOAT
E-AMP LIGASE

(Bacillus
subtilis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A  30
ALA A  35
LEU A  56
ALA A  43
 None
 0.83A 2vcvG-1mdfA:
undetectable		 2vcvG-1mdfA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pxt PEROXISOMAL
3-KETOACYL-COA
THIOLASE

(Saccharomyces
cerevisiae) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 LEU A 285
ALA A 131
LEU A 150
ALA A 281
 None
 0.92A 2vcvG-1pxtA:
undetectable		 2vcvG-1pxtA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzx HYPOTHETICAL PROTEIN
APC36103

(Geobacillus
stearothermophilus) 		PF02645
(DegV) 		4 LEU A  91
ALA A 271
ALA A 277
PHE A 279
 PLM  A 702 ( 4.5A)
PLM  A 702 ( 4.7A)
PLM  A 702 (-3.1A)
None
 0.97A 2vcvG-1pzxA:
undetectable		 2vcvG-1pzxA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5q PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis) 		PF00227
(Proteasome) 		4 LEU H  14
ALA H 167
LEU H 171
ALA H 146
 None
 1.01A 2vcvG-1q5qH:
undetectable		 2vcvG-1q5qH:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis) 		PF00227
(Proteasome) 		4 LEU H  14
ALA H 167
LEU H 171
ALA H 146
 None
 0.90A 2vcvG-1q5rH:
undetectable		 2vcvG-1q5rH:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8k EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2
SUBUNIT 1

(Homo sapiens) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		4 LEU A 215
ALA A 253
LEU A 250
ALA A 192
 None
 0.93A 2vcvG-1q8kA:
undetectable		 2vcvG-1q8kA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfx PROTEIN (PH 2.5 ACID
PHOSPHATASE)

(Aspergillus
niger) 		PF00328
(His_Phos_2) 		4 PHE A 260
LEU A  80
ALA A 259
PHE A  97
 None
 0.83A 2vcvG-1qfxA:
undetectable		 2vcvG-1qfxA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
ALPHA-SUBUNIT

(Pseudomonas
putida) 		PF00676
(E1_dh)
PF12573
(OxoDH_E1alpha_N) 		4 LEU A 301
PRO A 299
ALA A 228
ALA A 191
 None
 0.92A 2vcvG-1qs0A:
undetectable		 2vcvG-1qs0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6v SUBTILISIN-LIKE
SERINE PROTEASE

(Fervidobacterium
pennivorans) 		PF00082
(Peptidase_S8) 		4 PHE A 339
ALA A 391
LEU A 327
ALA A 337
 None
 0.86A 2vcvG-1r6vA:
undetectable		 2vcvG-1r6vA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rgi GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		4 PHE G 234
LEU G 244
LEU G 191
PHE G 183
 None
 0.85A 2vcvG-1rgiG:
undetectable		 2vcvG-1rgiG:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryy ALPHA-AMINO ACID
ESTER HYDROLASE

(Acetobacter
pasteurianus) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 LEU A 216
PRO A 326
LEU A 352
ALA A 348
 None
 1.01A 2vcvG-1ryyA:
undetectable		 2vcvG-1ryyA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ywf PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
PTPB

(Mycobacterium
tuberculosis) 		PF13350
(Y_phosphatase3) 		4 ALA A 260
LEU A 143
ALA A 139
PHE A 169
 None
 0.84A 2vcvG-1ywfA:
undetectable		 2vcvG-1ywfA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a81 CARB

(Pectobacterium
carotovorum) 		PF00378
(ECH_1) 		4 PHE A 127
LEU A 184
ALA A  99
ALA A 105
 None
 1.02A 2vcvG-2a81A:
undetectable		 2vcvG-2a81A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bgh VINORINE SYNTHASE

(Rauvolfia
serpentina) 		PF02458
(Transferase) 		4 PHE A 221
LEU A 397
ALA A 395
PHE A 350
 None
 0.87A 2vcvG-2bghA:
undetectable		 2vcvG-2bghA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cdq ASPARTOKINASE

(Arabidopsis
thaliana) 		PF00696
(AA_kinase) 		4 PHE A 482
LEU A 436
ALA A 439
PHE A 464
 None
 0.89A 2vcvG-2cdqA:
undetectable		 2vcvG-2cdqA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ed7 NETRIN RECEPTOR DCC

(Homo sapiens) 		PF00041
(fn3) 		4 LEU A  74
PRO A  21
ALA A  93
ALA A  44
 None
 0.96A 2vcvG-2ed7A:
undetectable		 2vcvG-2ed7A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fna CONSERVED
HYPOTHETICAL PROTEIN

(Sulfolobus
solfataricus) 		PF01637
(ATPase_2) 		4 PHE A 172
LEU A 126
ALA A 159
LEU A 156
 None
 0.87A 2vcvG-2fnaA:
2.4		 2vcvG-2fnaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2frv PERIPLASMIC
HYDROGENASE

(Desulfovibrio
gigas) 		no annotation 4 PHE L 480
LEU L 466
ALA L  79
ALA L  57
 None
FCO  L 537 (-3.4A)
None
None
 1.02A 2vcvG-2frvL:
undetectable		 2vcvG-2frvL:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gko SUBTILISIN
MICROBIAL SERINE
PROTEINASES

(Bacillus
subtilis) 		PF00082
(Peptidase_S8) 		4 PHE A 205
ALA A 251
LEU A 191
ALA A 203
 None
 0.88A 2vcvG-2gkoA:
undetectable		 2vcvG-2gkoA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 PHE A 356
LEU A 243
ALA A 159
LEU A 163
 None
 0.99A 2vcvG-2h4tA:
2.5		 2vcvG-2h4tA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i00 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 PHE A 309
PRO A 372
LEU A 365
PHE A 320
 None
 0.87A 2vcvG-2i00A:
undetectable		 2vcvG-2i00A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l5v PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1

(Homo sapiens) 		PF16550
(RPN13_C) 		4 PHE A 377
LEU A 301
LEU A 361
ALA A 365
 None
 0.97A 2vcvG-2l5vA:
undetectable		 2vcvG-2l5vA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY

(Ruegeria
pomeroyi) 		PF00072
(Response_reg) 		4 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.70A 2vcvG-2qsjA:
undetectable		 2vcvG-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7d RIBONUCLEASE II
FAMILY PROTEIN

(Deinococcus
radiodurans) 		PF00773
(RNB) 		4 PHE A  75
PRO A 341
ALA A 121
ALA A 125
 None
 0.92A 2vcvG-2r7dA:
undetectable		 2vcvG-2r7dA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x17 PUTATIVE FERRITIN
HOMOLOG

(Pyrococcus
furiosus) 		PF00210
(Ferritin) 		4 LEU 0   2
ALA 0 108
LEU 0 104
PHE 0  57
 None
 0.87A 2vcvG-2x170:
undetectable		 2vcvG-2x170:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 PHE A 414
PRO A 350
LEU A 334
ALA A 337
 None
 0.77A 2vcvG-2xh1A:
undetectable		 2vcvG-2xh1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yut PUTATIVE SHORT-CHAIN
OXIDOREDUCTASE

(Thermus
thermophilus) 		PF00106
(adh_short) 		4 LEU A 193
ALA A  15
LEU A  12
ALA A  73
 None
None
NAP  A 500 (-4.0A)
NAP  A 500 (-4.1A)
 0.99A 2vcvG-2yutA:
undetectable		 2vcvG-2yutA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		4 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.83A 2vcvG-2zhyA:
undetectable		 2vcvG-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anv D-SERINE DEHYDRATASE

(Gallus gallus) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 PRO A  90
LEU A  69
ALA A  72
PHE A 107
 None
 1.01A 2vcvG-3anvA:
undetectable		 2vcvG-3anvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqc COMPONENT B OF
HEXAPRENYL
DIPHOSPHATE SYNTHASE

(Micrococcus
luteus) 		PF00348
(polyprenyl_synt) 		4 LEU B 174
ALA B  79
LEU B 116
ALA B 119
 None
2DE  B 329 ( 4.4A)
2DE  B 329 ( 4.6A)
None
 0.99A 2vcvG-3aqcB:
undetectable		 2vcvG-3aqcB:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 LEU A 388
LEU A 333
ALA A 329
PHE A 697
 None
 0.92A 2vcvG-3aqpA:
1.9		 2vcvG-3aqpA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)

(Thermus
thermophilus) 		PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb) 		4 LEU A 513
PRO A 469
LEU A 466
ALA A 491
 None
 0.91A 2vcvG-3auoA:
undetectable		 2vcvG-3auoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6g CYTOCHROME P450 2R1

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 466
ALA A 322
LEU A 319
PHE A 165
 None
 0.99A 2vcvG-3c6gA:
undetectable		 2vcvG-3c6gA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d19 CONSERVED
METALLOPROTEIN

(Bacillus cereus) 		PF11155
(DUF2935) 		4 LEU A 112
LEU A  41
ALA A  56
PHE A  99
 None
 0.76A 2vcvG-3d19A:
undetectable		 2vcvG-3d19A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE

(Bacillus cereus) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PHE A 180
LEU A 198
ALA A 302
ALA A 176
 None
DAL  A 701 ( 4.1A)
None
None
 0.84A 2vcvG-3dhvA:
1.8		 2vcvG-3dhvA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvr ACETYL XYLAN
ESTERASE

(Bacillus
pumilus) 		PF05448
(AXE1) 		4 PRO A 197
LEU A 161
ALA A 157
PHE A  88
 None
 1.02A 2vcvG-3fvrA:
undetectable		 2vcvG-3fvrA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzd SELENOCYSTEINE LYASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		4 PHE C 260
LEU C 253
ALA C 267
ALA C 309
 None
 0.82A 2vcvG-3gzdC:
undetectable		 2vcvG-3gzdC:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd8 XYLANASE INHIBITOR

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 PHE A 104
ALA A 178
LEU A   6
ALA A 106
 None
 1.00A 2vcvG-3hd8A:
undetectable		 2vcvG-3hd8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i47 ENOYL COA
HYDRATASE/ISOMERASE
(CROTONASE)

(Legionella
pneumophila) 		PF00378
(ECH_1) 		4 LEU A  91
ALA A 120
ALA A 104
PHE A  61
 None
 0.86A 2vcvG-3i47A:
undetectable		 2vcvG-3i47A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 PHE A 149
ALA A 112
LEU A 116
ALA A 119
 None
 0.83A 2vcvG-3jb9A:
undetectable		 2vcvG-3jb9A:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq4 GASTRIC INTRINSIC
FACTOR

(Homo sapiens) 		PF01122
(Cobalamin_bind)
PF14478
(DUF4430) 		4 PRO A 188
LEU A 151
ALA A 154
PHE A 199
 None
 0.88A 2vcvG-3kq4A:
2.8		 2vcvG-3kq4A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no6 TRANSCRIPTIONAL
ACTIVATOR TENA

(Staphylococcus
epidermidis) 		PF03070
(TENA_THI-4) 		4 PHE A   3
LEU A 202
PRO A 136
ALA A 132
 None
 0.99A 2vcvG-3no6A:
undetectable		 2vcvG-3no6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3q MMOQ

(Methylococcus
capsulatus) 		PF08668
(HDOD) 		4 LEU A 207
PRO A 213
ALA A  87
PHE A 237
 None
 0.91A 2vcvG-3p3qA:
undetectable		 2vcvG-3p3qA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qll CITRATE LYASE

(Yersinia pestis) 		PF03328
(HpcH_HpaI) 		4 PHE A 214
LEU A 134
LEU A 150
ALA A 188
 None
 1.02A 2vcvG-3qllA:
undetectable		 2vcvG-3qllA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 PHE A2593
LEU A2516
ALA A2519
PHE A2528
 None
 0.66A 2vcvG-3vkgA:
undetectable		 2vcvG-3vkgA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrb IRON-SULFUR SUBUNIT
OF SUCCINATE
DEHYDROGENASE

(Ascaris suum) 		PF13085
(Fer2_3)
PF13534
(Fer4_17) 		4 LEU B 227
ALA B 211
LEU B 208
ALA B 258
 None
 0.89A 2vcvG-3vrbB:
undetectable		 2vcvG-3vrbB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ber PHOSPHOCHOLINE
TRANSFERASE ANKX

(Legionella
pneumophila) 		PF02661
(Fic)
PF12796
(Ank_2) 		4 LEU A  25
ALA A  52
LEU A  49
PHE A 311
 None
 0.84A 2vcvG-4berA:
undetectable		 2vcvG-4berA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cta CINA-LIKE PROTEIN

(Thermus
thermophilus) 		PF00994
(MoCF_biosynth)
PF02464
(CinA) 		4 PHE A 288
LEU A 275
ALA A 250
ALA A 285
 None
None
None
SO4  A 402 (-3.9A)
 0.97A 2vcvG-4ctaA:
undetectable		 2vcvG-4ctaA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3m BH0337 PROTEIN

(Bacillus
halodurans) 		PF09704
(Cas_Cas5d) 		4 PHE A   7
LEU A 135
PRO A  33
LEU A  58
 None
 0.81A 2vcvG-4f3mA:
undetectable		 2vcvG-4f3mA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)

(Mycobacteroides
abscessus) 		PF00202
(Aminotran_3) 		4 LEU A 222
ALA A 251
LEU A 247
PHE A 153
 None
 0.88A 2vcvG-4ffcA:
undetectable		 2vcvG-4ffcA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fn6 THIAMINASE-2

(Staphylococcus
aureus) 		PF03070
(TENA_THI-4) 		4 PHE A   3
LEU A 202
PRO A 136
ALA A 132
 None
None
CME  A 137 ( 3.2A)
None
 0.93A 2vcvG-4fn6A:
undetectable		 2vcvG-4fn6A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fte CAPSID PROTEIN ALPHA

(Flock House
virus) 		PF01829
(Peptidase_A6) 		4 PHE A  71
LEU A  59
PRO A  85
ALA A  70
 None
 1.02A 2vcvG-4fteA:
undetectable		 2vcvG-4fteA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gp1 POLYPRENYL
SYNTHETASE

(Pyrobaculum
calidifontis) 		PF00348
(polyprenyl_synt) 		4 LEU A  51
ALA A  71
LEU A  68
ALA A  20
 None
 1.00A 2vcvG-4gp1A:
undetectable		 2vcvG-4gp1A:
21.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hj2 GLUTATHIONE
S-TRANSFERASE A1

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A 108
PRO A 110
LEU A 213
ALA A 216
 None
LZ6  A 301 (-3.5A)
None
LZ6  A 301 ( 4.6A)
 0.84A 2vcvG-4hj2A:
36.5		 2vcvG-4hj2A:
90.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hj2 GLUTATHIONE
S-TRANSFERASE A1

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		5 PHE A  10
LEU A 107
PRO A 110
LEU A 213
ALA A 216
 None
LZ6  A 301 (-4.4A)
LZ6  A 301 (-3.5A)
None
LZ6  A 301 ( 4.6A)
 0.74A 2vcvG-4hj2A:
36.5		 2vcvG-4hj2A:
90.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i98 SEGREGATION AND
CONDENSATION PROTEIN
A
SEGREGATION AND
CONDENSATION PROTEIN
B

(Streptococcus
pneumoniae) 		PF02616
(SMC_ScpA)
PF04079
(SMC_ScpB) 		4 LEU B  87
ALA A 143
ALA B  99
PHE B 151
 None
 1.00A 2vcvG-4i98B:
undetectable		 2vcvG-4i98B:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idm DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00171
(Aldedh) 		4 PHE A 320
LEU A 412
LEU A 348
ALA A 351
 None
 1.02A 2vcvG-4idmA:
undetectable		 2vcvG-4idmA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt3 UNCHARACTERIZED
PROTEIN

(Pseudomonas
protegens) 		PF01832
(Glucosaminidase) 		4 PHE A  85
LEU A  63
ALA A  66
PHE A  40
 None
 0.79A 2vcvG-4kt3A:
undetectable		 2vcvG-4kt3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 SILKWORM STORAGE
PROTEIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 PHE A 105
LEU A 140
ALA A 109
PHE A 121
 None
 0.82A 2vcvG-4l37A:
undetectable		 2vcvG-4l37A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ope NRPS/PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A4287
ALA A4457
ALA A4576
PHE A4244
 None
 0.99A 2vcvG-4opeA:
undetectable		 2vcvG-4opeA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN

(Salmonella
enterica) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1) 		4 LEU A1316
ALA A1341
LEU A1338
ALA A1354
 None
 0.89A 2vcvG-4u48A:
undetectable		 2vcvG-4u48A:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wer DIACYLGLYCEROL
KINASE CATALYTIC
DOMAIN PROTEIN

(Enterococcus
faecalis) 		PF00781
(DAGK_cat) 		4 LEU A  31
ALA A   4
LEU A   6
PHE A  89
 None
 0.98A 2vcvG-4werA:
undetectable		 2vcvG-4werA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wt7 ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)

(Agrobacterium
vitis) 		PF13407
(Peripla_BP_4) 		4 ALA A 299
LEU A 295
ALA A  67
PHE A  63
 None
None
None
X9X  A 401 (-3.5A)
 0.99A 2vcvG-4wt7A:
3.0		 2vcvG-4wt7A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpx ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF13654
(AAA_32) 		4 PHE A 267
LEU A 258
ALA A 261
PHE A 290
 None
 0.83A 2vcvG-4zpxA:
undetectable		 2vcvG-4zpxA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zva DIGUANYLATE CYCLASE
DOSC

(Escherichia
coli) 		PF11563
(Protoglobin) 		4 LEU A  15
ALA A  79
LEU A  77
ALA A  27
 None
 0.96A 2vcvG-4zvaA:
undetectable		 2vcvG-4zvaA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zvb DIGUANYLATE CYCLASE
DOSC

(Escherichia
coli) 		PF11563
(Protoglobin) 		4 LEU A  15
ALA A  79
LEU A  77
ALA A  27
 None
 0.92A 2vcvG-4zvbA:
undetectable		 2vcvG-4zvbA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2g CARBOXYLIC ESTER
HYDROLASE

(Hungatella
hathewayi) 		PF00135
(COesterase) 		4 LEU A 248
ALA A 272
LEU A 269
PHE A  42
 None
 1.00A 2vcvG-5a2gA:
undetectable		 2vcvG-5a2gA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn5 PEPTIDOGLYCAN
HYDROLASE FLGJ

(Salmonella
enterica) 		PF01832
(Glucosaminidase) 		4 PHE A 204
LEU A 178
ALA A 181
PHE A 155
 None
 0.93A 2vcvG-5dn5A:
undetectable		 2vcvG-5dn5A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2e BETA-LACTAMASE

(Yersinia
enterocolitica) 		PF13354
(Beta-lactamase2) 		4 PHE A 128
ALA A 175
ALA A  55
PHE A  51
 None
 0.80A 2vcvG-5e2eA:
undetectable		 2vcvG-5e2eA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01547
(SBP_bac_1) 		4 PHE A 245
LEU A 281
LEU A 332
ALA A 244
 None
 1.00A 2vcvG-5g5zA:
undetectable		 2vcvG-5g5zA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Homo sapiens) 		PF16647
(GCSF) 		4 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 0.94A 2vcvG-5gw9A:
2.4		 2vcvG-5gw9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2x ADRENOCORTICAL
DYSPLASIA PROTEIN
HOMOLOG

(Homo sapiens) 		PF10341
(TPP1) 		4 PHE A 173
LEU A 183
ALA A 161
ALA A 142
 None
 0.85A 2vcvG-5i2xA:
undetectable		 2vcvG-5i2xA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3e PUTATIVE
DEOXYRIBONUCLEASE-2

(Burkholderia
thailandensis) 		PF03265
(DNase_II) 		4 LEU A 115
LEU A  81
ALA A 125
PHE A  70
 None
 0.93A 2vcvG-5i3eA:
undetectable		 2vcvG-5i3eA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2

(Homo sapiens) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 PHE A 381
LEU A 352
LEU A 534
PHE A 205
 None
ID8  A 601 (-4.1A)
None
None
 0.98A 2vcvG-5ikrA:
undetectable		 2vcvG-5ikrA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		4 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.86A 2vcvG-5im6A:
undetectable		 2vcvG-5im6A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irr SEPTIN-LIKE PROTEIN

(Chlamydomonas
reinhardtii) 		PF00735
(Septin) 		4 PHE A 298
LEU A 305
ALA A 372
LEU A 368
 None
 1.02A 2vcvG-5irrA:
undetectable		 2vcvG-5irrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oar BETA-HEXOSAMINIDASE

(Aspergillus
oryzae) 		no annotation 4 LEU A  46
ALA A  64
LEU B 156
ALA B 152
 None
 0.85A 2vcvG-5oarA:
undetectable		 2vcvG-5oarA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN

(Mycolicibacterium
smegmatis) 		no annotation 4 PRO B 173
LEU B 264
ALA B 267
PHE B 149
 None
 0.97A 2vcvG-5op0B:
undetectable		 2vcvG-5op0B:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thm ESTERASE-6

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 PHE A 279
ALA A 264
LEU A 261
PHE A  42
 None
None
MLY  A 256 ( 4.9A)
None
 0.91A 2vcvG-5thmA:
undetectable		 2vcvG-5thmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u89 AMINO ACID
ADENYLATION DOMAIN
PROTEIN
MBTH DOMAIN PROTEIN

(Geobacillus sp.
Y4.1MC1) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF03621
(MbtH)
PF13193
(AMP-binding_C) 		4 LEU A 787
PRO B  36
ALA A 822
LEU B  19
 None
 0.96A 2vcvG-5u89A:
undetectable		 2vcvG-5u89A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v4l ADENYLOSUCCINATE
LYASE

(Cryptococcus
neoformans) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 LEU A 245
PRO A 247
ALA A 182
LEU A 179
 None
 0.94A 2vcvG-5v4lA:
3.2		 2vcvG-5v4lA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0s 60 KDA CHAPERONIN

(Escherichia
coli) 		PF00118
(Cpn60_TCP1) 		4 LEU A 221
ALA A 275
LEU A 262
ALA A 258
 None
 0.81A 2vcvG-5w0sA:
undetectable		 2vcvG-5w0sA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yem CATALASE

(Mycothermus
thermophilus) 		no annotation 4 LEU A 171
LEU A 207
ALA A 210
PHE A 188
 None
 0.89A 2vcvG-5yemA:
2.3		 2vcvG-5yemA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus) 		no annotation 4 PRO A 708
LEU A 442
ALA A 445
PHE A 742
 None
 0.81A 2vcvG-6aunA:
undetectable		 2vcvG-6aunA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bev THIOSULFATE
SULFURTRANSFERASE/RH
ODANESE-LIKE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		no annotation 4 PHE A  59
LEU A  75
LEU A  48
ALA A  51
 None
 0.92A 2vcvG-6bevA:
undetectable		 2vcvG-6bevA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cnh SERINE/THREONINE-PRO
TEIN KINASE PRP4
HOMOLOG

(Homo sapiens) 		no annotation 4 PRO A 858
ALA A 901
LEU A 898
PHE A 923
 None
 0.80A 2vcvG-6cnhA:
1.2		 2vcvG-6cnhA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d95 -

(-) 		no annotation 4 LEU A  68
LEU A  95
ALA A  98
PHE A  60
 None
 1.00A 2vcvG-6d95A:
undetectable		 2vcvG-6d95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkx ACETYL XYLAN
ESTERASE

(metagenome) 		no annotation 4 PHE C  90
LEU C 197
ALA C 165
ALA C 181
 None
 0.85A 2vcvG-6fkxC:
undetectable		 2vcvG-6fkxC:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdt -

(-) 		no annotation 4 LEU A 399
ALA A 453
LEU A 449
ALA A 475
 None
 0.97A 2vcvG-6gdtA:
1.6		 2vcvG-6gdtA:
undetectable