SIMILAR PATTERNS OF AMINO ACIDS FOR 2VCV_E_ASDE1224
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bou | 4,5-DIOXYGENASEALPHA CHAIN (Sphingomonaspaucimobilis) |
PF07746(LigA) | 5 | LEU A 37LEU A 61ALA A 73LEU A 75PHE A 53 | None | 1.18A | 2vcvE-1bouA:0.0 | 2vcvE-1bouA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dkd | GROEL (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 5 | LEU A 221LEU A 237ALA A 275LEU A 262ALA A 258 | None | 1.15A | 2vcvE-1dkdA:undetectable | 2vcvE-1dkdA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | PHE A 478PRO A 172LEU A 177LEU A 494PHE A 181 | None | 1.13A | 2vcvE-1ebvA:0.0 | 2vcvE-1ebvA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f0x | D-LACTATEDEHYDROGENASE (Escherichiacoli) |
PF01565(FAD_binding_4)PF09330(Lact-deh-memb) | 5 | PRO A 199LEU A 203LEU A 187ALA A 177PHE A 263 | None | 0.96A | 2vcvE-1f0xA:0.0 | 2vcvE-1f0xA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g68 | BETA-LACTAMASE PSE-4 (Pseudomonasaeruginosa) |
PF13354(Beta-lactamase2) | 5 | PRO A 145LEU A 162LEU A 139ALA A 135PHE A 72 | None | 1.07A | 2vcvE-1g68A:0.0 | 2vcvE-1g68A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h2t | 80 KDA NUCLEAR CAPBINDING PROTEIN (Homo sapiens) |
PF02854(MIF4G)PF09088(MIF4G_like)PF09090(MIF4G_like_2) | 5 | PHE C 292LEU C 376LEU C 391ALA C 394PHE C 356 | None | 1.21A | 2vcvE-1h2tC:2.5 | 2vcvE-1h2tC:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htj | KIAA0380 (Homo sapiens) |
PF09128(RGS-like) | 5 | LEU F 383LEU F 369ALA F 397ALA F 346PHE F 342 | None | 0.94A | 2vcvE-1htjF:0.1 | 2vcvE-1htjF:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ihm | CAPSID PROTEIN (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 5 | LEU A1437LEU A1233LEU A1459ALA A1457PHE A1231 | None | 1.21A | 2vcvE-1ihmA:0.0 | 2vcvE-1ihmA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1la1 | GROEL (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 5 | LEU A 221LEU A 237ALA A 275LEU A 262ALA A 258 | None | 1.06A | 2vcvE-1la1A:0.0 | 2vcvE-1la1A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m66 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE (Leishmaniamexicana) |
PF01210(NAD_Gly3P_dh_N)PF07479(NAD_Gly3P_dh_C) | 5 | LEU A 339LEU A 321ALA A 220LEU A 233ALA A 232 | PLM A 402 ( 4.9A)NonePLM A 402 ( 4.0A)PLM A 402 ( 4.3A)PLM A 402 ( 4.0A) | 1.19A | 2vcvE-1m66A:undetectable | 2vcvE-1m66A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n9b | BETA-LACTAMASE SHV-2 (Klebsiellapneumoniae) |
PF13354(Beta-lactamase2) | 5 | PRO A 145LEU A 162LEU A 139ALA A 135PHE A 72 | None | 1.02A | 2vcvE-1n9bA:undetectable | 2vcvE-1n9bA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pxt | PEROXISOMAL3-KETOACYL-COATHIOLASE (Saccharomycescerevisiae) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 285LEU A 148ALA A 131LEU A 150ALA A 281 | None | 1.09A | 2vcvE-1pxtA:undetectable | 2vcvE-1pxtA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q15 | CARA (Pectobacteriumcarotovorum) |
PF00733(Asn_synthase)PF09147(DUF1933) | 5 | LEU A 231LEU A 227ALA A 256LEU A 253PHE A 397 | None | 1.25A | 2vcvE-1q15A:undetectable | 2vcvE-1q15A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1txk | GLUCANS BIOSYNTHESISPROTEIN G (Escherichiacoli) |
PF04349(MdoG) | 5 | TYR A 218PRO A 373LEU A 372LEU A 238ALA A 214 | None | 1.14A | 2vcvE-1txkA:undetectable | 2vcvE-1txkA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz6 | PUTATIVE SUGARKINASE (Salmonellaenterica) |
PF00294(PfkB) | 5 | PHE A 125LEU A 132ALA A 140LEU A 142ALA A 145 | None | 1.09A | 2vcvE-1tz6A:undetectable | 2vcvE-1tz6A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v4g | GLUTAMATE--CYSTEINELIGASE (Escherichiacoli) |
PF04262(Glu_cys_ligase) | 5 | LEU A 420LEU A 12LEU A 359ALA A 358PHE A 159 | None | 1.27A | 2vcvE-1v4gA:undetectable | 2vcvE-1v4gA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vb3 | THREONINE SYNTHASE (Escherichiacoli) |
PF00291(PALP)PF14821(Thr_synth_N) | 5 | LEU A 394PRO A 397LEU A 400LEU A 104ALA A 377 | None | 1.16A | 2vcvE-1vb3A:undetectable | 2vcvE-1vb3A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vkn | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Thermotogamaritima) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | TYR A 260LEU A 129LEU A 214LEU A 158ALA A 157 | None | 1.26A | 2vcvE-1vknA:undetectable | 2vcvE-1vknA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w0m | TRIOSEPHOSPHATEISOMERASE (Thermoproteustenax) |
PF00121(TIM)PF05690(ThiG) | 5 | LEU A 218PRO A 221LEU A 222LEU A 192ALA A 191 | None | 1.26A | 2vcvE-1w0mA:undetectable | 2vcvE-1w0mA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wv9 | RHODANESE HOMOLOGTT1651 (Thermusthermophilus) |
no annotation | 5 | PRO A 6LEU A 9ALA A 89LEU A 83PHE A 34 | None | 1.23A | 2vcvE-1wv9A:undetectable | 2vcvE-1wv9A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xls | ORPHAN NUCLEARRECEPTOR NR1I3 (Mus musculus) |
PF00104(Hormone_recep) | 5 | LEU E 123LEU E 189LEU E 277ALA E 273PHE E 185 | None | 1.22A | 2vcvE-1xlsE:undetectable | 2vcvE-1xlsE:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv9 | ORPHAN NUCLEARRECEPTOR NR1I3 (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU B 113LEU B 179LEU B 267ALA B 263PHE B 175 | None | 1.29A | 2vcvE-1xv9B:1.4 | 2vcvE-1xv9B:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yq3 | SUCCINATEDEHYDROGENASE IPSUBUNIT (Gallus gallus) |
PF13085(Fer2_3)PF13534(Fer4_17) | 5 | LEU B 203LEU B 212ALA B 187LEU B 184ALA B 234 | None | 0.96A | 2vcvE-1yq3B:undetectable | 2vcvE-1yq3B:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7z | HUMAN COXSACKIEVIRUSA21 (Enterovirus C) |
PF00073(Rhv) | 5 | PRO 3 88LEU 3 94LEU 3 86ALA 3 167PHE 3 115 | None | 1.25A | 2vcvE-1z7z3:undetectable | 2vcvE-1z7z3:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zg4 | BETA-LACTAMASE TEM (Escherichiacoli) |
PF13354(Beta-lactamase2) | 5 | PRO A 145LEU A 162LEU A 139ALA A 135PHE A 72 | None | 1.02A | 2vcvE-1zg4A:undetectable | 2vcvE-1zg4A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8x | DIHYDROLIPOYLDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | PHE A 350LEU A 316PRO A 346LEU A 420ALA A 417 | FAD A 480 ( 4.8A)FAD A 480 (-3.7A)NoneNoneNone | 1.25A | 2vcvE-2a8xA:undetectable | 2vcvE-2a8xA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2am2 | UDP-N-ACETYLMURAMOYLALANINE-D-GLUTAMYL-LYSINE-D-ALANYL-D-ALANINE LIGASE, MURFPROTEIN (Streptococcuspneumoniae) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | PHE A 256LEU A 121LEU A 286ALA A 258PHE A 260 | None | 1.27A | 2vcvE-2am2A:undetectable | 2vcvE-2am2A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2azk | GERANYLGERANYLPYROPHOSPHATESYNTHETASE (Sulfolobussolfataricus) |
PF00348(polyprenyl_synt) | 5 | LEU A 186LEU A 167ALA A 173LEU A 171ALA A 128 | None | 1.20A | 2vcvE-2azkA:undetectable | 2vcvE-2azkA:24.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3t | PROTEINMETHYLTRANSFERASEHEMK (Escherichiacoli) |
PF13847(Methyltransf_31) | 6 | TYR A 255LEU A 236LEU A 116LEU A 114ALA A 227PHE A 169 | None | 1.26A | 2vcvE-2b3tA:undetectable | 2vcvE-2b3tA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bgh | VINORINE SYNTHASE (Rauvolfiaserpentina) |
PF02458(Transferase) | 5 | PHE A 221LEU A 348LEU A 397ALA A 395PHE A 350 | None | 1.07A | 2vcvE-2bghA:undetectable | 2vcvE-2bghA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dou | PROBABLEN-SUCCINYLDIAMINOPIMELATEAMINOTRANSFERASE (Thermusthermophilus) |
PF00155(Aminotran_1_2) | 5 | LEU A 357LEU A 361ALA A 367LEU A 365ALA A 299 | NoneSO4 A 502 (-4.3A)NoneNoneNone | 1.02A | 2vcvE-2douA:undetectable | 2vcvE-2douA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ds2 | SWEET PROTEINMABINLIN-2 CHAIN ASWEET PROTEINMABINLIN-2 CHAIN B (Capparismasaikai) |
PF00234(Tryp_alpha_amyl)no annotation | 5 | LEU B 7LEU B 14ALA A 17LEU A 15ALA B 29 | None | 1.24A | 2vcvE-2ds2B:undetectable | 2vcvE-2ds2B:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g7g | RHA04620, PUTATIVETRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF02909(TetR_C) | 5 | LEU A 200LEU A 122ALA A 134ALA A 139PHE A 80 | None | 1.28A | 2vcvE-2g7gA:undetectable | 2vcvE-2g7gA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9i | HYPOTHETICAL PROTEIN (Helicobacterpylori) |
PF05211(NLBH) | 5 | TYR A 241LEU A 141LEU A 252ALA A 248PHE A 178 | None | 1.25A | 2vcvE-2i9iA:undetectable | 2vcvE-2i9iA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivf | ETHYLBENZENEDEHYDROGENASEGAMMA-SUBUNIT (Aromatoleumaromaticum) |
PF09459(EB_dh) | 5 | PHE C 187LEU C 177ALA C 62ALA C 95PHE C 97 | None | 1.14A | 2vcvE-2ivfC:undetectable | 2vcvE-2ivfC:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgp | TYROCIDINESYNTHETASE 3 (Brevibacillusbrevis) |
PF00550(PP-binding)PF00668(Condensation) | 5 | PHE A 430LEU A 418LEU A 414ALA A 378PHE A 282 | None | 1.21A | 2vcvE-2jgpA:undetectable | 2vcvE-2jgpA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oq5 | TRANSMEMBRANEPROTEASE, SERINE 11E (Homo sapiens) |
PF00089(Trypsin) | 5 | LEU A 46ALA A 106LEU A 108ALA A 66PHE A 68 | None | 1.22A | 2vcvE-2oq5A:undetectable | 2vcvE-2oq5A:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p1r | LIPID KINASE YEGS (Salmonellaenterica) |
PF00781(DAGK_cat) | 5 | PRO A 92LEU A 93ALA A 112LEU A 109ALA A 24 | None | 1.19A | 2vcvE-2p1rA:undetectable | 2vcvE-2p1rA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p90 | HYPOTHETICAL PROTEINCGL1923 (Corynebacteriumglutamicum) |
PF09754(PAC2) | 5 | PRO A 110LEU A 91LEU A 32ALA A 179PHE A 119 | None | 1.21A | 2vcvE-2p90A:undetectable | 2vcvE-2p90A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r77 | PHOSPHATIDYLETHANOLAMINE-BINDINGPROTEIN, PUTATIVE (Plasmodiumfalciparum) |
PF01161(PBP) | 5 | LEU A 46PRO A 20LEU A 42LEU A 25PHE A 35 | None | 1.24A | 2vcvE-2r77A:undetectable | 2vcvE-2r77A:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7d | RIBONUCLEASE IIFAMILY PROTEIN (Deinococcusradiodurans) |
PF00773(RNB) | 5 | PHE A 75PRO A 341LEU A 348ALA A 121ALA A 125 | None | 0.94A | 2vcvE-2r7dA:undetectable | 2vcvE-2r7dA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x66 | PRNB (Pseudomonasfluorescens) |
PF08933(DUF1864) | 5 | LEU A 279LEU A 299ALA A 273LEU A 236PHE A 303 | None | 1.25A | 2vcvE-2x66A:undetectable | 2vcvE-2x66A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeb | SUCCINATEDEHYDROGENASE[UBIQUINONE]IRON-SULFUR SUBUNIT,MITOCHONDRIAL (Sus scrofa) |
PF13085(Fer2_3)PF13534(Fer4_17) | 5 | LEU B 203LEU B 212ALA B 187LEU B 184ALA B 234 | None | 0.98A | 2vcvE-3aebB:undetectable | 2vcvE-3aebB:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeu | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Rhodobactercapsulatus) |
PF00148(Oxidored_nitro) | 5 | LEU A 117LEU A 121ALA A 85LEU A 89ALA A 72 | None | 1.29A | 2vcvE-3aeuA:undetectable | 2vcvE-3aeuA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahx | BETA-GLUCOSIDASE A (Clostridiumcellulovorans) |
PF00232(Glyco_hydro_1) | 5 | PHE A 281PRO A 167LEU A 221ALA A 194ALA A 253 | None | 1.30A | 2vcvE-3ahxA:0.5 | 2vcvE-3ahxA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aq2 | 6B PROTEIN (Agrobacteriumvitis) |
PF02027(RolB_RolC) | 5 | LEU A 20ALA A 27LEU A 24ALA A 133PHE A 131 | None | 1.11A | 2vcvE-3aq2A:undetectable | 2vcvE-3aq2A:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cfz | UPF0100 PROTEINMJ1186 (Methanocaldococcusjannaschii) |
PF13531(SBP_bac_11) | 5 | PRO A 51LEU A 317LEU A 48ALA A 93PHE A 115 | None | 1.15A | 2vcvE-3cfzA:undetectable | 2vcvE-3cfzA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cij | UPF0100 PROTEINAF_0094 (Archaeoglobusfulgidus) |
PF13531(SBP_bac_11) | 5 | PRO A 46LEU A 315LEU A 43ALA A 88PHE A 110 | None | 1.18A | 2vcvE-3cijA:undetectable | 2vcvE-3cijA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fds | DNA POLYMERASESLIDING CLAMP C (Sulfolobussolfataricus) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | TYR D 56PHE D 57LEU D 16LEU D 100ALA D 4 | None | 1.28A | 2vcvE-3fdsD:undetectable | 2vcvE-3fdsD:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fs2 | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Brucellamelitensis) |
PF00793(DAHP_synth_1) | 5 | PHE A 236LEU A 186ALA A 227LEU A 224ALA A 200 | None | 1.16A | 2vcvE-3fs2A:undetectable | 2vcvE-3fs2A:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7n | LIPASE (Penicilliumexpansum) |
PF01764(Lipase_3) | 5 | TYR A 194PHE A 162PRO A 102LEU A 137ALA A 136 | None | 1.27A | 2vcvE-3g7nA:undetectable | 2vcvE-3g7nA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hfw | PROTEINADP-RIBOSYLARGININEHYDROLASE (Homo sapiens) |
PF03747(ADP_ribosyl_GH) | 5 | LEU A 292LEU A 43ALA A 307LEU A 17ALA A 13 | None CL A 360 (-4.7A)NoneNoneNone | 1.21A | 2vcvE-3hfwA:undetectable | 2vcvE-3hfwA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibj | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I)PF01590(GAF)PF13185(GAF_2) | 5 | PHE A 505LEU A 403LEU A 414ALA A 421ALA A 518 | None | 1.30A | 2vcvE-3ibjA:undetectable | 2vcvE-3ibjA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jab | GAFB DOMAIN OFPHOSPHODIESTERASE 2A (Bos taurus) |
PF01590(GAF) | 5 | PHE B 505LEU B 403LEU B 414ALA B 421ALA B 518 | None | 1.16A | 2vcvE-3jabB:3.3 | 2vcvE-3jabB:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kez | PUTATIVE SUGARBINDING PROTEIN (Bacteroidesvulgatus) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | TYR A 52LEU A 205LEU A 198ALA A 218LEU A 222 | None | 1.28A | 2vcvE-3kezA:1.3 | 2vcvE-3kezA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kio | RIBONUCLEASE H2SUBUNIT C (Mus musculus) |
PF08615(RNase_H2_suC) | 5 | PRO C 33LEU C 32LEU C 68ALA C 61PHE C 48 | None | 1.13A | 2vcvE-3kioC:undetectable | 2vcvE-3kioC:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkr | COATOMER SUBUNITALPHA (Bos taurus) |
PF06957(COPI_C) | 5 | LEU B1034PRO B1037LEU B1038LEU B 943PHE B 959 | None | 1.09A | 2vcvE-3mkrB:1.1 | 2vcvE-3mkrB:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nog | DESIGNED ANKYRINREPEAT PROTEIN (syntheticconstruct) |
PF00023(Ank)PF12796(Ank_2) | 5 | LEU D 126LEU D 133ALA D 120LEU D 117ALA D 149 | None | 1.13A | 2vcvE-3nogD:undetectable | 2vcvE-3nogD:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8l | 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE (Oryctolaguscuniculus) |
PF00365(PFK) | 5 | LEU A 136LEU A 156LEU A 105ALA A 101PHE A 128 | None | 1.22A | 2vcvE-3o8lA:undetectable | 2vcvE-3o8lA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p1t | PUTATIVEHISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Burkholderiapseudomallei) |
PF00155(Aminotran_1_2) | 5 | PHE A 210LEU A 236LEU A 72ALA A 208PHE A 195 | None | 1.23A | 2vcvE-3p1tA:undetectable | 2vcvE-3p1tA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p3q | MMOQ (Methylococcuscapsulatus) |
PF08668(HDOD) | 5 | LEU A 207PRO A 213ALA A 87ALA A 153PHE A 237 | None | 1.10A | 2vcvE-3p3qA:undetectable | 2vcvE-3p3qA:25.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psh | PROTEIN HI_1472 (Haemophilusinfluenzae) |
PF01497(Peripla_BP_2) | 5 | TYR A 340LEU A 181LEU A 161LEU A 307ALA A 306 | None | 1.17A | 2vcvE-3pshA:undetectable | 2vcvE-3pshA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9d | PROTEINCPN_0803/CP_1068/CPJ0803/CPB0832 (Chlamydiapneumoniae) |
PF17435(DUF5414) | 5 | LEU A 18LEU A 10ALA A 76LEU A 69PHE A 55 | None | 1.27A | 2vcvE-3q9dA:3.1 | 2vcvE-3q9dA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qxz | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | TYR A 127LEU A 18ALA A 100LEU A 53ALA A 113 | None | 1.13A | 2vcvE-3qxzA:undetectable | 2vcvE-3qxzA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3re1 | UROPORPHYRINOGEN-IIISYNTHETASE (Pseudomonassyringae groupgenomosp. 3) |
PF02602(HEM4) | 5 | LEU A 18LEU A 6LEU A 247ALA A 246PHE A 214 | None | 1.24A | 2vcvE-3re1A:undetectable | 2vcvE-3re1A:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rg2 | ENTEROBACTINSYNTHASE COMPONENT E(ENTE),2,3-DIHYDRO-2,3-DIHYDROXYBENZOATESYNTHETASE,ISOCHROISMATASE(ENTB) (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF13193(AMP-binding_C) | 5 | LEU A 305LEU A 299LEU A 290ALA A 289PHE A 265 | None | 1.02A | 2vcvE-3rg2A:undetectable | 2vcvE-3rg2A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sir | CASPASE (Drosophilamelanogaster) |
PF00656(Peptidase_C14) | 5 | PHE A 58LEU A 253LEU A 215LEU A 202PHE A 134 | None | 1.20A | 2vcvE-3sirA:undetectable | 2vcvE-3sirA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tix | CHROMODOMAIN-CONTAININGPROTEIN 1 (Schizosaccharomycespombe) |
no annotation | 5 | PHE B 734LEU B 743LEU B 757ALA B 760PHE B 767 | None | 1.04A | 2vcvE-3tixB:undetectable | 2vcvE-3tixB:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vu2 | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME,CHLOROPLASTIC/AMYLOPLASTIC (Oryza sativa) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 5 | LEU A 265LEU A 256LEU A 221ALA A 186PHE A 203 | None | 1.04A | 2vcvE-3vu2A:undetectable | 2vcvE-3vu2A:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdj | ENCA BETA-LACTAMASE (syntheticconstruct) |
PF13354(Beta-lactamase2) | 5 | PRO A 145LEU A 162LEU A 139ALA A 135PHE A 72 | None | 1.02A | 2vcvE-3zdjA:undetectable | 2vcvE-3zdjA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ev4 | CARBAPENEM-HYDROLIZING BETA-LACTAMASESFC-1 (Serratiafonticola) |
PF13354(Beta-lactamase2) | 5 | PRO A 145LEU A 162LEU A 139ALA A 135PHE A 72 | None | 1.00A | 2vcvE-4ev4A:undetectable | 2vcvE-4ev4A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ezi | UNCHARACTERIZEDPROTEIN (Legionellapneumophila) |
no annotation | 6 | PRO A 222LEU A 336ALA A 225LEU A 338ALA A 355PHE A 359 | None | 1.34A | 2vcvE-4eziA:undetectable | 2vcvE-4eziA:22.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homo sapiens) |
PF00043(GST_C)PF02798(GST_N) | 6 | TYR A 9PHE A 10LEU A 107PRO A 110LEU A 213ALA A 216 | LZ6 A 301 (-4.6A)NoneLZ6 A 301 (-4.4A)LZ6 A 301 (-3.5A)NoneLZ6 A 301 ( 4.6A) | 0.84A | 2vcvE-4hj2A:36.4 | 2vcvE-4hj2A:90.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyq | PHOSPHOLIPASE A1 (Streptomycesalbidoflavus) |
PF13472(Lipase_GDSL_2) | 5 | PHE A 48LEU A 229LEU A 140ALA A 34ALA A 7 | None | 1.14A | 2vcvE-4hyqA:undetectable | 2vcvE-4hyqA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ia5 | MYOSIN-CROSSREACTIVEANTIGEN (Lactobacillusacidophilus) |
PF06100(MCRA) | 5 | PHE A 178LEU A 194ALA A 201LEU A 152PHE A 169 | None | 1.18A | 2vcvE-4ia5A:undetectable | 2vcvE-4ia5A:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | SILKWORM STORAGEPROTEIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | PHE A 105LEU A 140LEU A 25ALA A 109PHE A 121 | None | 1.26A | 2vcvE-4l37A:undetectable | 2vcvE-4l37A:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lry | PTS-DEPENDENTDIHYDROXYACETONEKINASE OPERONREGULATORY PROTEIN (Escherichiacoli) |
PF00989(PAS) | 5 | LEU C 268LEU C 301LEU C 303ALA C 284PHE C 275 | None | 1.30A | 2vcvE-4lryC:undetectable | 2vcvE-4lryC:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2j | AMINOTRANSFERASE (Streptomyceslavendulae) |
PF00155(Aminotran_1_2) | 5 | LEU A 291LEU A 375LEU A 345ALA A 357PHE A 317 | None | 1.11A | 2vcvE-4m2jA:undetectable | 2vcvE-4m2jA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m4d | LIPOPOLYSACCHARIDE-BINDING PROTEIN (Mus musculus) |
PF01273(LBP_BPI_CETP)PF02886(LBP_BPI_CETP_C) | 5 | LEU A 144PRO A 152LEU A 232LEU A 216PHE A 247 | NoneNoneNonePC1 A 506 (-4.2A)None | 1.28A | 2vcvE-4m4dA:undetectable | 2vcvE-4m4dA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | LEU A3792LEU A3821LEU A3724ALA A3811PHE A3817 | None | 1.22A | 2vcvE-4rh7A:undetectable | 2vcvE-4rh7A:5.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3k | UNCHARACTERIZEDPROTEIN PA3435 (Pseudomonasaeruginosa) |
PF00258(Flavodoxin_1) | 5 | LEU A 52LEU A 148ALA A 32LEU A 30ALA A 28 | None | 1.29A | 2vcvE-5b3kA:undetectable | 2vcvE-5b3kA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5r | GASDERMIN-A3 (Mus musculus) |
PF04598(Gasdermin) | 5 | LEU A 296PRO A 329LEU A 328LEU A 334ALA A 338 | None | 1.26A | 2vcvE-5b5rA:undetectable | 2vcvE-5b5rA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cdk | CHAPERONIN 60B1 (Chlamydomonasreinhardtii) |
PF00118(Cpn60_TCP1) | 5 | LEU A 29LEU A 45ALA A 83LEU A 70ALA A 66 | None | 1.10A | 2vcvE-5cdkA:undetectable | 2vcvE-5cdkA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e43 | BETA-LACTAMASE (Streptosporangiumroseum) |
PF13354(Beta-lactamase2) | 5 | PRO A 146LEU A 163LEU A 140ALA A 136PHE A 72 | None | 1.02A | 2vcvE-5e43A:undetectable | 2vcvE-5e43A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eoe | BETA-LACTAMASE (Pseudomonasaeruginosa) |
PF13354(Beta-lactamase2) | 5 | PRO A 138LEU A 155LEU A 132ALA A 128PHE A 64 | None | 1.12A | 2vcvE-5eoeA:undetectable | 2vcvE-5eoeA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fql | IDURONATE-2-SULFATASE (Homo sapiens) |
PF00884(Sulfatase) | 5 | TYR A 122PHE A 123LEU A 439LEU A 413ALA A 414 | None | 1.29A | 2vcvE-5fqlA:undetectable | 2vcvE-5fqlA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 5 | PHE A 116LEU A 142ALA A 75ALA A 114PHE A 132 | None | 1.22A | 2vcvE-5hpjA:undetectable | 2vcvE-5hpjA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 5 | PHE A 116LEU A 162LEU A 146ALA A 75ALA A 114 | None | 1.29A | 2vcvE-5hpjA:undetectable | 2vcvE-5hpjA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2h | O-METHYLTRANSFERASEFAMILY 2 (Planctopiruslimnophila) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 5 | LEU A 95LEU A 71ALA A 31LEU A 29ALA A 26 | None | 1.30A | 2vcvE-5i2hA:undetectable | 2vcvE-5i2hA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja1 | ENTEROBACTINBIOSYNTHESIS PROTEINYBDZENTEROBACTINSYNTHASE COMPONENT F (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF03621(MbtH)PF13193(AMP-binding_C) | 5 | PHE B 7PRO B 34LEU B 33ALA A 826LEU B 17 | None | 1.21A | 2vcvE-5ja1B:undetectable | 2vcvE-5ja1B:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1b | WD REPEAT-CONTAININGPROTEIN 48 (Homo sapiens) |
PF00400(WD40)PF11816(DUF3337) | 5 | LEU B 460LEU B 390LEU B 466ALA B 469PHE B 507 | None | 1.27A | 2vcvE-5k1bB:undetectable | 2vcvE-5k1bB:14.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ll7 | BETA-LACTAMASE (Escherichiacoli) |
no annotation | 5 | PRO A 145LEU A 162LEU A 139ALA A 135PHE A 72 | None | 1.09A | 2vcvE-5ll7A:undetectable | 2vcvE-5ll7A:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | LEU A4042PRO A4040LEU A4124ALA A4141LEU A4113 | None | 1.04A | 2vcvE-5nugA:undetectable | 2vcvE-5nugA:3.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | TYR A3176PHE A3179LEU A3536LEU A3509ALA A3512 | None | 1.30A | 2vcvE-5nugA:undetectable | 2vcvE-5nugA:3.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o5o | RNASE ADAPTERPROTEIN RAPZ (Escherichiacoli) |
PF03668(ATP_bind_2) | 5 | LEU A 82PRO A 80LEU A 3LEU A 74ALA A 70 | None | 1.13A | 2vcvE-5o5oA:undetectable | 2vcvE-5o5oA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5um8 | GLYCOPROTEIN GP120 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 5 | LEU G 122LEU G 193ALA G 161ALA G 174PHE G 176 | None | 1.10A | 2vcvE-5um8G:undetectable | 2vcvE-5um8G:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0s | 60 KDA CHAPERONIN (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 5 | LEU A 221LEU A 237ALA A 275LEU A 262ALA A 258 | None | 1.03A | 2vcvE-5w0sA:undetectable | 2vcvE-5w0sA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xpg | UNCHARACTERIZEDPROTEIN (Thermusthermophilus) |
no annotation | 5 | PHE A 163LEU A 24PRO A 26LEU A 112ALA A 113 | None | 1.13A | 2vcvE-5xpgA:undetectable | 2vcvE-5xpgA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6co7 | PREDICTED PROTEIN (Nematostellavectensis) |
no annotation | 5 | PHE A 644LEU A 581ALA A 587LEU A 585ALA A 613 | None | 1.05A | 2vcvE-6co7A:undetectable | 2vcvE-6co7A:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cv9 | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 6 (Mus musculus) |
no annotation | 5 | LEU A 145LEU A 152ALA A 139LEU A 136ALA A 163 | None | 1.19A | 2vcvE-6cv9A:3.8 | 2vcvE-6cv9A:18.81 |