SIMILAR PATTERNS OF AMINO ACIDS FOR 2VCV_A_ASDA1224

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b74 GLUTAMATE RACEMASE

(Aquifex
pyrophilus) 		PF01177
(Asp_Glu_race) 		4 PHE A   6
ALA A  77
LEU A  52
ALA A  55
 None
 1.18A 2vcvA-1b74A:
0.9		 2vcvA-1b74A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bgc GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Bos taurus) 		PF16647
(GCSF) 		4 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 1.06A 2vcvA-1bgcA:
undetectable		 2vcvA-1bgcA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxc XYLOSE ISOMERASE

(Thermus
caldophilus) 		PF01261
(AP_endonuc_2) 		4 TYR A 369
PRO A 360
ALA A 363
LEU A 361
 None
 1.03A 2vcvA-1bxcA:
0.0		 2vcvA-1bxcA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0x D-LACTATE
DEHYDROGENASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF09330
(Lact-deh-memb) 		4 PRO A 199
LEU A 187
ALA A 177
PHE A 263
 None
 0.99A 2vcvA-1f0xA:
0.0		 2vcvA-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f2p AMINOPEPTIDASE

(Streptomyces
griseus) 		PF04389
(Peptidase_M28) 		4 PHE A 159
ALA A 271
ALA A  82
PHE A 125
 None
 1.07A 2vcvA-1f2pA:
0.0		 2vcvA-1f2pA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 PHE B 509
ALA B 669
LEU B 667
PHE B 524
 None
 1.16A 2vcvA-1gl9B:
0.0		 2vcvA-1gl9B:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hpl LIPASE

(Equus caballus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 TYR A 270
PRO A 305
LEU A 224
PHE A 198
 None
 1.14A 2vcvA-1hplA:
0.0		 2vcvA-1hplA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oah CYTOCHROME C NITRITE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF02335
(Cytochrom_C552) 		4 TYR A 106
PHE A 108
PRO A 300
ALA A 427
 None
CL  A1527 (-4.6A)
None
None
 1.13A 2vcvA-1oahA:
0.5		 2vcvA-1oahA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw9 PULMONARY
SURFACTANT-ASSOCIATE
D PROTEIN D

(Homo sapiens) 		PF00059
(Lectin_C)
PF09006
(Surfac_D-trimer) 		4 ALA A 264
LEU A 260
ALA A 248
PHE A 250
 None
 1.15A 2vcvA-1pw9A:
undetectable		 2vcvA-1pw9A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vff BETA-GLUCOSIDASE

(Pyrococcus
horikoshii) 		PF00232
(Glyco_hydro_1) 		4 TYR A 399
ALA A  14
LEU A 106
ALA A  66
 None
 1.12A 2vcvA-1vffA:
0.0		 2vcvA-1vffA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyt GLYCINE
DEHYDROGENASE
(DECARBOXYLATING)
SUBUNIT 1
GLYCINE
DEHYDROGENASE
SUBUNIT 2
(P-PROTEIN)

(Thermus
thermophilus) 		PF02347
(GDC-P) 		4 TYR B 238
PHE B 257
PRO A  31
LEU B 223
 None
 1.17A 2vcvA-1wytB:
undetectable		 2vcvA-1wytB:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ya0 SMG-7 TRANSCRIPT
VARIANT 2

(Homo sapiens) 		PF10373
(EST1_DNA_bind)
PF10374
(EST1) 		4 TYR A 102
PHE A  65
LEU A  36
ALA A  64
 None
 1.15A 2vcvA-1ya0A:
undetectable		 2vcvA-1ya0A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yoc HYPOTHETICAL PROTEIN
PA1835

(Pseudomonas
aeruginosa) 		PF14539
(DUF4442) 		4 TYR A  95
PHE A 134
ALA A  67
ALA A 136
 None
 1.17A 2vcvA-1yocA:
undetectable		 2vcvA-1yocA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ywf PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
PTPB

(Mycobacterium
tuberculosis) 		PF13350
(Y_phosphatase3) 		4 ALA A 260
LEU A 143
ALA A 139
PHE A 169
 None
 0.97A 2vcvA-1ywfA:
undetectable		 2vcvA-1ywfA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zmz CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 PHE A  40
LEU A  60
ALA A  36
PHE A  89
 None
 1.01A 2vcvA-1zmzA:
undetectable		 2vcvA-1zmzA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvh IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN

(Camelus
dromedarius) 		PF07686
(V-set) 		4 PHE A  37
ALA A  50
LEU A  34
ALA A  97
 None
 1.11A 2vcvA-1zvhA:
undetectable		 2vcvA-1zvhA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abq FRUCTOSE 1-PHOSPHATE
KINASE

(Bacillus
halodurans) 		PF00294
(PfkB) 		4 PRO A  35
LEU A  71
ALA A  55
PHE A  80
 None
 1.15A 2vcvA-2abqA:
undetectable		 2vcvA-2abqA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b42 XYLANASE INHIBITOR-I

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 PHE A 102
ALA A 176
LEU A   4
ALA A 104
 None
 1.01A 2vcvA-2b42A:
undetectable		 2vcvA-2b42A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3y URACIL-DNA
GLYCOSYLASE

(Thermus
thermophilus) 		PF03167
(UDG) 		4 PHE A  56
PRO A 122
LEU A 127
ALA A 157
 None
 1.07A 2vcvA-2d3yA:
undetectable		 2vcvA-2d3yA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fj0 CARBOXYLIC ESTER
HYDROLASE

(Manduca sexta) 		PF00135
(COesterase) 		4 PHE A 316
ALA A 303
LEU A 300
PHE A  70
 None
 0.87A 2vcvA-2fj0A:
undetectable		 2vcvA-2fj0A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A

(Archaeoglobus
fulgidus) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 TYR A 245
PRO A 491
ALA A 571
LEU A 568
 None
 0.97A 2vcvA-2fjaA:
undetectable		 2vcvA-2fjaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gko SUBTILISIN
MICROBIAL SERINE
PROTEINASES

(Bacillus
subtilis) 		PF00082
(Peptidase_S8) 		4 PHE A 205
ALA A 251
LEU A 191
ALA A 203
 None
 0.85A 2vcvA-2gkoA:
undetectable		 2vcvA-2gkoA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h36 HYPOTHETICAL PROTEIN
SIFV0014

(Sulfolobus
islandicus
filamentous
virus) 		PF07118
(DUF1374) 		4 TYR X  85
ALA X  25
LEU X  22
PHE X  89
 None
 1.09A 2vcvA-2h36X:
undetectable		 2vcvA-2h36X:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i00 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 PHE A 309
PRO A 372
LEU A 365
PHE A 320
 None
 1.00A 2vcvA-2i00A:
undetectable		 2vcvA-2i00A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgp TYROCIDINE
SYNTHETASE 3

(Brevibacillus
brevis) 		PF00550
(PP-binding)
PF00668
(Condensation) 		4 PHE A 389
LEU A 335
ALA A 338
PHE A 501
 None
 0.98A 2vcvA-2jgpA:
undetectable		 2vcvA-2jgpA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kzt PROGRAMMED CELL
DEATH PROTEIN 4

(Homo sapiens) 		PF02847
(MA3) 		4 TYR A 278
PRO A 201
LEU A 223
ALA A 268
 None
 0.86A 2vcvA-2kztA:
undetectable		 2vcvA-2kztA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lq6 BROMODOMAIN-CONTAINI
NG PROTEIN 1

(Homo sapiens) 		PF13771
(zf-HC5HC2H) 		4 TYR A 328
PHE A 350
ALA A 383
ALA A 355
 None
 1.00A 2vcvA-2lq6A:
undetectable		 2vcvA-2lq6A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1r LIPID KINASE YEGS

(Salmonella
enterica) 		PF00781
(DAGK_cat) 		4 PRO A  92
ALA A 112
LEU A 109
ALA A  24
 None
 1.14A 2vcvA-2p1rA:
undetectable		 2vcvA-2p1rA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY

(Ruegeria
pomeroyi) 		PF00072
(Response_reg) 		4 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.79A 2vcvA-2qsjA:
undetectable		 2vcvA-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7d RIBONUCLEASE II
FAMILY PROTEIN

(Deinococcus
radiodurans) 		PF00773
(RNB) 		4 PHE A  75
PRO A 341
ALA A 121
ALA A 125
 None
 0.90A 2vcvA-2r7dA:
undetectable		 2vcvA-2r7dA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wl3 CATECHOL
2,3-DIOXYGENASE

(Rhodococcus sp.
DK17) 		PF00903
(Glyoxalase) 		4 TYR A  23
LEU A 223
ALA A 226
PHE A 252
 None
 1.11A 2vcvA-2wl3A:
undetectable		 2vcvA-2wl3A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 PHE A 414
PRO A 350
LEU A 334
ALA A 337
 None
 0.74A 2vcvA-2xh1A:
undetectable		 2vcvA-2xh1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF00106
(adh_short) 		4 TYR A 147
PHE A 146
LEU A 249
ALA A 183
 None
 1.14A 2vcvA-2y93A:
undetectable		 2vcvA-2y93A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yx6 HYPOTHETICAL PROTEIN
PH0822

(Pyrococcus
horikoshii) 		PF02579
(Nitro_FeMo-Co) 		4 PRO A  56
ALA A  76
LEU A  55
PHE A  27
 None
 1.15A 2vcvA-2yx6A:
undetectable		 2vcvA-2yx6A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0j PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1438

(Thermus
thermophilus) 		PF04029
(2-ph_phosp) 		4 PRO A 222
ALA A  31
LEU A  35
ALA A  39
 None
 1.13A 2vcvA-2z0jA:
undetectable		 2vcvA-2z0jA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		4 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.84A 2vcvA-2zhyA:
undetectable		 2vcvA-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj9 AMPC

(Escherichia
coli) 		PF00144
(Beta-lactamase) 		4 PHE A 158
ALA A  77
LEU A  73
PHE A 170
 None
 1.15A 2vcvA-2zj9A:
undetectable		 2vcvA-2zj9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anv D-SERINE DEHYDRATASE

(Gallus gallus) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 PRO A  90
LEU A  69
ALA A  72
PHE A 107
 None
 1.11A 2vcvA-3anvA:
undetectable		 2vcvA-3anvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjr PUTATIVE
CARBOXYLESTERASE

(Lactobacillus
plantarum) 		PF07859
(Abhydrolase_3) 		4 PHE A 190
LEU A 253
ALA A 256
PHE A  57
 None
 1.10A 2vcvA-3bjrA:
undetectable		 2vcvA-3bjrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkh LYTIC
TRANSGLYCOSYLASE

(Pseudomonas
virus phiKZ) 		PF01464
(SLT)
PF01471
(PG_binding_1) 		4 PHE A 133
LEU A 109
ALA A 112
PHE A 118
 None
 0.97A 2vcvA-3bkhA:
undetectable		 2vcvA-3bkhA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3by5 COBALAMIN
BIOSYNTHESIS PROTEIN

(Agrobacterium
fabrum) 		PF01890
(CbiG_C) 		4 PRO A  46
ALA A  69
LEU A  73
ALA A 103
 None
 1.08A 2vcvA-3by5A:
undetectable		 2vcvA-3by5A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eak NBBCII10-FGLA

(Camelus
dromedarius) 		PF07686
(V-set) 		4 PHE A  40
ALA A  53
LEU A  37
ALA A 100
 None
 0.97A 2vcvA-3eakA:
undetectable		 2vcvA-3eakA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhh OUTER MEMBRANE HEME
RECEPTOR SHUA

(Shigella
dysenteriae) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 TYR A 217
PHE A  91
PRO A 227
LEU A  87
 None
 1.01A 2vcvA-3fhhA:
undetectable		 2vcvA-3fhhA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvr ACETYL XYLAN
ESTERASE

(Bacillus
pumilus) 		PF05448
(AXE1) 		4 PRO A 197
LEU A 161
ALA A 157
PHE A  88
 None
 0.95A 2vcvA-3fvrA:
undetectable		 2vcvA-3fvrA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2i ESTERASE

(Xanthomonas
oryzae) 		PF03583
(LIP) 		4 PHE A 310
PRO A 208
LEU A 139
ALA A 238
 None
 1.16A 2vcvA-3h2iA:
undetectable		 2vcvA-3h2iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h35 UNCHARACTERIZED
PROTEIN ABO_0056

(Alcanivorax
borkumensis) 		no annotation 4 TYR A  75
LEU A 160
ALA A 119
PHE A 112
 None
None
None
EDO  A 184 (-3.8A)
 1.08A 2vcvA-3h35A:
undetectable		 2vcvA-3h35A:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd8 XYLANASE INHIBITOR

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 PHE A 104
ALA A 178
LEU A   6
ALA A 106
 None
 0.96A 2vcvA-3hd8A:
undetectable		 2vcvA-3hd8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ide CAPSID PROTEIN VP2

(Infectious
pancreatic
necrosis virus) 		PF01766
(Birna_VP2) 		4 TYR A 312
PRO A 250
ALA A 280
ALA A 324
 None
 1.07A 2vcvA-3ideA:
undetectable		 2vcvA-3ideA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 PHE A 149
ALA A 112
LEU A 116
ALA A 119
 None
 0.84A 2vcvA-3jb9A:
undetectable		 2vcvA-3jb9A:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4w UNCHARACTERIZED
PROTEIN BB4693

(Bordetella
bronchiseptica) 		PF04909
(Amidohydro_2) 		4 PRO A 151
ALA A 279
LEU A 275
PHE A   6
 None
 0.94A 2vcvA-3k4wA:
undetectable		 2vcvA-3k4wA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq4 GASTRIC INTRINSIC
FACTOR

(Homo sapiens) 		PF01122
(Cobalamin_bind)
PF14478
(DUF4430) 		4 PRO A 188
LEU A 151
ALA A 154
PHE A 199
 None
 0.82A 2vcvA-3kq4A:
2.4		 2vcvA-3kq4A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nog DESIGNED ANKYRIN
REPEAT PROTEIN

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2) 		4 PRO D  50
ALA D  42
LEU D  18
ALA D  38
 None
 1.08A 2vcvA-3nogD:
undetectable		 2vcvA-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrf APAG PROTEIN

(Pseudomonas
aeruginosa) 		PF14263
(DUF4354) 		4 PHE A 106
ALA A  31
LEU A 118
ALA A  72
 None
 1.17A 2vcvA-3nrfA:
undetectable		 2vcvA-3nrfA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1

(Bacillus
anthracis) 		PF00275
(EPSP_synthase) 		4 TYR A 400
PHE A 403
ALA A 243
LEU A 410
 None
 1.18A 2vcvA-3sg1A:
undetectable		 2vcvA-3sg1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sql GLYCOSYL HYDROLASE
FAMILY 3

(Synechococcus
sp. PCC 7002) 		PF00933
(Glyco_hydro_3) 		4 PHE A 501
PRO A 104
ALA A 108
LEU A 373
 None
 1.04A 2vcvA-3sqlA:
undetectable		 2vcvA-3sqlA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tdu DCN1-LIKE PROTEIN 1

(Homo sapiens) 		PF03556
(Cullin_binding) 		4 PHE A 117
LEU A 103
ALA A 106
PHE A 160
 None
 1.03A 2vcvA-3tduA:
undetectable		 2vcvA-3tduA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Schizosaccharomyces
pombe) 		no annotation 4 PHE B 734
LEU B 757
ALA B 760
PHE B 767
 None
 0.57A 2vcvA-3tixB:
undetectable		 2vcvA-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 PHE A2593
LEU A2516
ALA A2519
PHE A2528
 None
 0.59A 2vcvA-3vkgA:
undetectable		 2vcvA-3vkgA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zg6 NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-6

(Homo sapiens) 		PF02146
(SIR2) 		4 PHE A 107
PRO A 191
LEU A 195
ALA A 198
 None
 1.13A 2vcvA-3zg6A:
undetectable		 2vcvA-3zg6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zla NUCLEOPROTEIN

(Bunyamwera
orthobunyavirus) 		PF00952
(Bunya_nucleocap) 		4 TYR A  43
PHE A  42
LEU A  90
PHE A  26
 None
 1.05A 2vcvA-3zlaA:
undetectable		 2vcvA-3zlaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bev COPPER EFFLUX ATPASE

(Legionella
pneumophila) 		PF00122
(E1-E2_ATPase)
PF00702
(Hydrolase) 		4 PRO A 383
ALA A 685
LEU A 386
ALA A 336
 None
 1.11A 2vcvA-4bevA:
undetectable		 2vcvA-4bevA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dap SUGAR FERMENTATION
STIMULATION PROTEIN
A

(Escherichia
coli) 		PF03749
(SfsA) 		4 PHE A 177
ALA A  92
LEU A  88
ALA A 179
 None
 1.01A 2vcvA-4dapA:
undetectable		 2vcvA-4dapA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fai CG5976, ISOFORM B

(Drosophila
melanogaster) 		PF04389
(Peptidase_M28) 		4 TYR A 329
ALA A 155
LEU A 149
ALA A 324
 None
 1.12A 2vcvA-4faiA:
undetectable		 2vcvA-4faiA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g68 ABC TRANSPORTER

(Caldanaerobius) 		PF01547
(SBP_bac_1) 		4 TYR B 144
PHE B 271
ALA B 249
ALA B 270
 None
 0.95A 2vcvA-4g68B:
undetectable		 2vcvA-4g68B:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 TYR A  93
PHE A  91
ALA A 310
ALA A  86
 None
 0.95A 2vcvA-4gysA:
undetectable		 2vcvA-4gysA:
17.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hj2 GLUTATHIONE
S-TRANSFERASE A1

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 TYR A   9
PHE A  10
PRO A 110
ALA A 216
 LZ6  A 301 (-4.6A)
None
LZ6  A 301 (-3.5A)
LZ6  A 301 ( 4.6A)
 0.67A 2vcvA-4hj2A:
36.4		 2vcvA-4hj2A:
90.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hj2 GLUTATHIONE
S-TRANSFERASE A1

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 TYR A   9
PRO A 110
LEU A 213
ALA A 216
 LZ6  A 301 (-4.6A)
LZ6  A 301 (-3.5A)
None
LZ6  A 301 ( 4.6A)
 0.70A 2vcvA-4hj2A:
36.4		 2vcvA-4hj2A:
90.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		4 TYR A 367
ALA A 450
ALA A 413
PHE A 438
 None
 1.08A 2vcvA-4hwvA:
undetectable		 2vcvA-4hwvA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jzy CRYPTOCHROME-1

(Drosophila
melanogaster) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 PHE A 272
PRO A 205
LEU A  61
PHE A  42
 None
NH4  A 602 ( 4.9A)
None
None
 1.01A 2vcvA-4jzyA:
undetectable		 2vcvA-4jzyA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9q BENZOYLFORMATE
DECARBOXYLASE

(Polynucleobacter
necessarius) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 PRO A 119
ALA A 115
LEU A  75
ALA A  96
 None
 1.09A 2vcvA-4k9qA:
undetectable		 2vcvA-4k9qA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l0c DEFORMYLASE

(Pseudomonas
putida) 		PF12697
(Abhydrolase_6) 		4 PRO A  29
ALA A  35
LEU A  27
ALA A  42
 None
 1.07A 2vcvA-4l0cA:
undetectable		 2vcvA-4l0cA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lpq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN

(Xylanimonas
cellulosilytica) 		PF01471
(PG_binding_1)
PF03734
(YkuD) 		4 TYR A 151
PHE A 171
ALA A 193
ALA A 175
 None
 0.85A 2vcvA-4lpqA:
undetectable		 2vcvA-4lpqA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzy NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Enterococcus
faecalis) 		PF04095
(NAPRTase) 		4 PHE A  86
ALA A 122
LEU A 126
PHE A  68
 None
 1.14A 2vcvA-4mzyA:
undetectable		 2vcvA-4mzyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ot9 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT

(Homo sapiens) 		PF12796
(Ank_2) 		4 PRO A 553
ALA A 588
LEU A 547
ALA A 580
 None
 1.17A 2vcvA-4ot9A:
undetectable		 2vcvA-4ot9A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd3 NONMUSCLE MYOSIN
HEAVY CHAIN B,
ALPHA-ACTININ A
CHIMERA PROTEIN

(Dictyostelium
discoideum;
Homo sapiens) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 ALA A 795
LEU A 792
ALA A 867
PHE A 865
 None
 1.02A 2vcvA-4pd3A:
undetectable		 2vcvA-4pd3A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9z UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF13622
(4HBT_3) 		4 ALA A 103
LEU A  44
ALA A  47
PHE A 107
 None
 0.92A 2vcvA-4r9zA:
undetectable		 2vcvA-4r9zA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvs PROBABLE QUINONE
REDUCTASE QOR
(NADPH:QUINONE
REDUCTASE)
(ZETA-CRYSTALLIN
HOMOLOG PROTEIN)

(Mycobacterium
tuberculosis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ALA A 120
LEU A 124
ALA A 284
PHE A 280
 None
 1.17A 2vcvA-4rvsA:
undetectable		 2vcvA-4rvsA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tlv ADP-RIBOSYLATING
TOXIN CARDS

(Mycoplasma
pneumoniae) 		PF02917
(Pertussis_S1) 		4 PHE A 127
PRO A 210
ALA A 213
ALA A 122
 None
 1.00A 2vcvA-4tlvA:
undetectable		 2vcvA-4tlvA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wt7 ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)

(Agrobacterium
vitis) 		PF13407
(Peripla_BP_4) 		4 ALA A 299
LEU A 295
ALA A  67
PHE A  63
 None
None
None
X9X  A 401 (-3.5A)
 1.00A 2vcvA-4wt7A:
undetectable		 2vcvA-4wt7A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9e DEOXYGUANOSINETRIPHO
SPHATE
TRIPHOSPHOHYDROLASE

(Escherichia
coli) 		PF01966
(HD) 		4 PHE A  55
LEU A 277
ALA A 280
PHE A 286
 None
 0.99A 2vcvA-4x9eA:
undetectable		 2vcvA-4x9eA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7m BETA-XYLOSIDASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 TYR A 674
LEU A 627
ALA A 662
PHE A 660
 None
 0.88A 2vcvA-5a7mA:
undetectable		 2vcvA-5a7mA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axk TRNA(HIS)-5'-GUANYLY
LTRANSFERASE (THG1)
LIKE PROTEIN

(Methanosarcina
acetivorans) 		PF04446
(Thg1)
PF14413
(Thg1C) 		4 ALA A  98
LEU A  95
ALA A  50
PHE A  73
 None
 1.14A 2vcvA-5axkA:
undetectable		 2vcvA-5axkA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2e BETA-LACTAMASE

(Yersinia
enterocolitica) 		PF13354
(Beta-lactamase2) 		4 PHE A 128
ALA A 175
ALA A  55
PHE A  51
 None
 0.84A 2vcvA-5e2eA:
undetectable		 2vcvA-5e2eA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5foj NANOBODY

(Camelus
dromedarius) 		PF07686
(V-set) 		4 PRO A 111
ALA A  50
LEU A  33
ALA A  99
 None
 1.04A 2vcvA-5fojA:
undetectable		 2vcvA-5fojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gin C/D BOX METHYLATION
GUIDE
RIBONUCLEOPROTEIN
COMPLEX ANOP56
SUBUNIT

(Sulfolobus
solfataricus) 		PF01798
(Nop) 		4 TYR A 165
PHE A 169
LEU A 214
ALA A 217
 None
 1.02A 2vcvA-5ginA:
undetectable		 2vcvA-5ginA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Homo sapiens) 		PF16647
(GCSF) 		4 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 0.90A 2vcvA-5gw9A:
undetectable		 2vcvA-5gw9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12

(Kluyveromyces
lactis) 		no annotation 4 PRO A 166
LEU A 136
ALA A 138
PHE A  66
 None
 1.05A 2vcvA-5h55A:
undetectable		 2vcvA-5h55A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmn AAC3-I

(uncultured
bacterium) 		PF00583
(Acetyltransf_1) 		4 TYR A  70
PHE A  52
LEU A  19
ALA A  54
 None
 1.17A 2vcvA-5hmnA:
undetectable		 2vcvA-5hmnA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmq 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE

(Pseudomonas
putida) 		PF00903
(Glyoxalase)
PF01261
(AP_endonuc_2)
PF14696
(Glyoxalase_5) 		4 PHE A 464
PRO A 399
LEU A 376
ALA A 379
 None
 1.11A 2vcvA-5hmqA:
undetectable		 2vcvA-5hmqA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		4 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.87A 2vcvA-5im6A:
undetectable		 2vcvA-5im6A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jo9 RIBITOL
2-DEHYDROGENASE

(Bradyrhizobium
japonicum) 		PF00106
(adh_short) 		4 PHE A 240
PRO A 195
LEU A 199
ALA A 202
 SOR  A 302 ( 4.7A)
None
None
None
 0.90A 2vcvA-5jo9A:
undetectable		 2vcvA-5jo9A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus) 		no annotation 4 PRO A  89
ALA A 207
LEU A 203
PHE A  57
 None
 0.75A 2vcvA-5n9mA:
undetectable		 2vcvA-5n9mA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN

(Mycolicibacterium
smegmatis) 		no annotation 4 PRO B 173
LEU B 264
ALA B 267
PHE B 149
 None
 0.98A 2vcvA-5op0B:
undetectable		 2vcvA-5op0B:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thm ESTERASE-6

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 PHE A 279
ALA A 264
LEU A 261
PHE A  42
 None
None
MLY  A 256 ( 4.9A)
None
 0.92A 2vcvA-5thmA:
undetectable		 2vcvA-5thmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens) 		no annotation 4 TYR A 841
PRO A 775
LEU A 716
ALA A 712
 None
 0.96A 2vcvA-5vanA:
undetectable		 2vcvA-5vanA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y5a KLLA0F20702P

(Kluyveromyces
lactis) 		no annotation 4 PHE A 432
LEU A 473
ALA A 476
PHE A 577
 None
 0.91A 2vcvA-5y5aA:
undetectable		 2vcvA-5y5aA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yz0 SERINE/THREONINE-PRO
TEIN KINASE ATR

(Homo sapiens) 		no annotation 4 PHE A2532
PRO A2512
ALA A2627
LEU A2623
 None
 1.09A 2vcvA-5yz0A:
2.6		 2vcvA-5yz0A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cnh SERINE/THREONINE-PRO
TEIN KINASE PRP4
HOMOLOG

(Homo sapiens) 		no annotation 4 PRO A 858
ALA A 901
LEU A 898
PHE A 923
 None
 0.83A 2vcvA-6cnhA:
undetectable		 2vcvA-6cnhA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elc VARIANT SURFACE
GLYCOPROTEIN

(Trypanosoma
brucei) 		no annotation 4 TYR A 194
PHE A 266
ALA A  40
LEU A  36
 None
 1.00A 2vcvA-6elcA:
undetectable		 2vcvA-6elcA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftx -

(-) 		no annotation 4 PHE W 361
ALA W 421
LEU W 418
ALA W 388
 None
 1.16A 2vcvA-6ftxW:
undetectable		 2vcvA-6ftxW:
undetectable