SIMILAR PATTERNS OF AMINO ACIDS FOR 2VCT_C_ASDC1223
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dlk | THROMBIN HEAVY CHAIN (Bos taurus) |
PF00089(Trypsin) | 4 | ILE B 181GLY B 211LEU B 209LEU B 123 | None | 0.89A | 2vctC-1dlkB:0.0 | 2vctC-1dlkB:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ea9 | CYCLOMALTODEXTRINASE (Bacillus sp.(in: Bacteria)) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | ILE C 314GLY C 321LEU C 236PHE C 241 | None | 0.85A | 2vctC-1ea9C:0.0 | 2vctC-1ea9C:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gl9 | REVERSE GYRASE (Archaeoglobusfulgidus) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 4 | ILE B 187LEU B 220LEU B 240PHE B 236 | None | 0.91A | 2vctC-1gl9B:0.0 | 2vctC-1gl9B:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyl | HYPODERMA LINEATUMCOLLAGENASE (Hypodermalineatum) |
PF00089(Trypsin) | 4 | ILE A 181GLY A 211LEU A 209LEU A 123 | None | 0.79A | 2vctC-1hylA:0.0 | 2vctC-1hylA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0h | NEOPULLULANASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | ILE A 508LEU A 520PHE A 445PHE A 379 | None | 0.81A | 2vctC-1j0hA:0.0 | 2vctC-1j0hA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1khd | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Pectobacteriumcarotovorum) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | LEU A 135LEU A 136PHE A 139PHE A 335 | None | 0.88A | 2vctC-1khdA:2.1 | 2vctC-1khdA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o2d | ALCOHOLDEHYDROGENASE,IRON-CONTAINING (Thermotogamaritima) |
PF00465(Fe-ADH) | 4 | ILE A 23GLY A 21LEU A 52LEU A 53 | None | 0.89A | 2vctC-1o2dA:0.6 | 2vctC-1o2dA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szq | 2-METHYLCITRATEDEHYDRATASE (Escherichiacoli) |
PF03972(MmgE_PrpD) | 4 | ILE A 483GLY A 78LEU A 49LEU A 447 | None | 0.89A | 2vctC-1szqA:0.0 | 2vctC-1szqA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t11 | TRIGGER FACTOR (Vibrio cholerae) |
PF00254(FKBP_C)PF05697(Trigger_N)PF05698(Trigger_C) | 4 | TYR A 221ILE A 195GLY A 293PHE A 233 | None | 0.92A | 2vctC-1t11A:0.3 | 2vctC-1t11A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xb2 | ELONGATION FACTORTS, MITOCHONDRIAL (Bos taurus) |
PF00889(EF_TS) | 5 | ILE B 120GLY B 121LEU B 242LEU B 239PHE B 147 | None | 1.39A | 2vctC-1xb2B:undetectable | 2vctC-1xb2B:24.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xuq | SUPEROXIDE DISMUTASE (Bacillusanthracis) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | ILE A 162LEU A 142PHE A 116PHE A 113 | None | 0.93A | 2vctC-1xuqA:undetectable | 2vctC-1xuqA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8t | HYPOTHETICAL PROTEINRV0983 (Mycobacteriumtuberculosis) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 4 | ILE A 158GLY A 182LEU A 180LEU A 105 | None | 0.83A | 2vctC-1y8tA:undetectable | 2vctC-1y8tA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ya0 | SMG-7 TRANSCRIPTVARIANT 2 (Homo sapiens) |
PF10373(EST1_DNA_bind)PF10374(EST1) | 4 | ILE A 466GLY A 463LEU A 397LEU A 396 | None | 0.62A | 2vctC-1ya0A:4.1 | 2vctC-1ya0A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z9n | SUPEROXIDE DISMUTASE[CU-ZN] ([Haemophilus]ducreyi) |
PF00080(Sod_Cu) | 4 | ILE A 176LEU A 137PHE A 55PHE A 69 | None | 0.74A | 2vctC-1z9nA:undetectable | 2vctC-1z9nA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z9p | SUPEROXIDE DISMUTASE[CU-ZN] ([Haemophilus]ducreyi) |
PF00080(Sod_Cu) | 4 | ILE A 176LEU A 137PHE A 55PHE A 69 | None | 0.83A | 2vctC-1z9pA:undetectable | 2vctC-1z9pA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aj7 | HYPOTHETICAL PROTEINBH3618 (Bacillushalodurans) |
PF02623(FliW) | 4 | ILE A 20GLY A 123LEU A 83PHE A 94 | NoneNoneNoneEDO A 152 ( 4.0A) | 0.88A | 2vctC-2aj7A:undetectable | 2vctC-2aj7A:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aps | PROTEIN (CU,ZNSUPEROXIDEDISMUTASE) (Actinobacilluspleuropneumoniae) |
PF00080(Sod_Cu) | 4 | ILE A 166LEU A 127PHE A 45PHE A 59 | None | 0.79A | 2vctC-2apsA:undetectable | 2vctC-2apsA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqt | SUPEROXIDE DISMUTASE[CU-ZN] (Neisseriameningitidis) |
no annotation | 4 | ILE C 185LEU C 146PHE C 64PHE C 78 | None | 0.79A | 2vctC-2aqtC:undetectable | 2vctC-2aqtC:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dej | PROBABLEGALACTOKINASE (Pyrococcushorikoshii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | ILE A 88GLY A 87LEU A 58PHE A 75 | None | 0.68A | 2vctC-2dejA:undetectable | 2vctC-2dejA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2et6 | (3R)-HYDROXYACYL-COADEHYDROGENASE (Candidatropicalis) |
PF00106(adh_short) | 4 | ILE A 450GLY A 529LEU A 320PHE A 342 | None | 0.93A | 2vctC-2et6A:undetectable | 2vctC-2et6A:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f91 | HEPATOPANCREASTRYPSIN (Astacusleptodactylus) |
PF00089(Trypsin) | 4 | ILE A 181GLY A 211LEU A 209LEU A 123 | CD A 405 ( 4.9A)NoneNoneNone | 0.89A | 2vctC-2f91A:undetectable | 2vctC-2f91A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpq | BOTULINUM NEUROTOXIND LIGHT CHAIN (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | TYR A 367ILE A 102GLY A 103LEU A 110 | None | 0.92A | 2vctC-2fpqA:undetectable | 2vctC-2fpqA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gnp | TRANSCRIPTIONALREGULATOR (Streptococcuspneumoniae) |
PF04198(Sugar-bind) | 4 | ILE A 210GLY A 209LEU A 121LEU A 124 | None | 0.77A | 2vctC-2gnpA:undetectable | 2vctC-2gnpA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi9 | PLASMA SERINEPROTEASE INHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | ILE A 249LEU A 363LEU A 280PHE A 275 | None | 0.86A | 2vctC-2hi9A:undetectable | 2vctC-2hi9A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iwg | 52 KDA RO PROTEIN (Homo sapiens) |
PF00622(SPRY)PF13765(PRY) | 4 | ILE B 126GLY B 74LEU B 49PHE B 54 | None | 0.80A | 2vctC-2iwgB:undetectable | 2vctC-2iwgB:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l8k | NON-STRUCTURALPROTEIN 7 (Equinearteritis virus) |
PF16749(Arteri_nsp7a) | 4 | ILE A 86LEU A 48LEU A 68PHE A 71 | None | 0.93A | 2vctC-2l8kA:undetectable | 2vctC-2l8kA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m3e | INTEGRIN ALPHA-L (Homo sapiens) |
PF00357(Integrin_alpha) | 4 | ILE A1073GLY A1074LEU A1078LEU A1081 | None | 0.87A | 2vctC-2m3eA:undetectable | 2vctC-2m3eA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ncj | UNCHARACTERIZEDPROTEIN (Cronobactersakazakii) |
PF07445(PriC) | 4 | ILE A 21GLY A 22LEU A 46LEU A 50 | None | 0.73A | 2vctC-2ncjA:2.4 | 2vctC-2ncjA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfv | EXOCYST COMPLEXCOMPONENT EXO70 (Saccharomycescerevisiae) |
PF03081(Exo70) | 4 | ILE A 472GLY A 473LEU A 477LEU A 480 | None | 0.93A | 2vctC-2pfvA:5.1 | 2vctC-2pfvA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2plj | LYSINE/ORNITHINEDECARBOXYLASE (Vibriovulnificus) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | ILE A 232LEU A 61PHE A 236PHE A 250 | None | 0.81A | 2vctC-2pljA:undetectable | 2vctC-2pljA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qza | SECRETED EFFECTORPROTEIN (Salmonellaenterica) |
PF13599(Pentapeptide_4)PF13979(SopA_C)PF13981(SopA) | 4 | ILE A 609LEU A 689PHE A 693PHE A 651 | None | 0.88A | 2vctC-2qzaA:1.6 | 2vctC-2qzaA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5x | UNCHARACTERIZEDCONSERVED PROTEIN (Geobacilluskaustophilus) |
PF08868(YugN) | 4 | ILE A 71GLY A 57ARG A 37LEU A 74 | None | 0.90A | 2vctC-2r5xA:undetectable | 2vctC-2r5xA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v5e | GLIAL CELLLINE-DERIVEDNEUROTROPHIC FACTOR (Homo sapiens) |
PF00019(TGF_beta) | 4 | ILE B 134GLY B 132LEU B 43PHE B 107 | None | 0.92A | 2vctC-2v5eB:undetectable | 2vctC-2v5eB:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vx4 | CELLVIBRIO JAPONICUSMANNANASE CJMAN26C (Cellvibriojaponicus) |
PF02156(Glyco_hydro_26) | 4 | ILE A 291GLY A 293LEU A 323LEU A 320 | None | 0.85A | 2vctC-2vx4A:undetectable | 2vctC-2vx4A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 4 | ILE A 549ARG A 606LEU A 582PHE A 682 | None | 0.89A | 2vctC-2vz9A:undetectable | 2vctC-2vz9A:6.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnw | ACTIVATED BYTRANSCRIPTION FACTORSSRB (Salmonellaenterica) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 4 | GLY A 424ARG A 26LEU A 422LEU A 33 | None | 0.89A | 2vctC-2wnwA:undetectable | 2vctC-2wnwA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wwo | SUPEROXIDE DISMUTASE[CU-ZN] (Yersiniapseudotuberculosis) |
PF00080(Sod_Cu) | 4 | ILE A 160LEU A 121PHE A 39PHE A 53 | None | 0.87A | 2vctC-2wwoA:undetectable | 2vctC-2wwoA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x2u | PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RET (Homo sapiens) |
PF00028(Cadherin) | 4 | ILE A 176LEU A 212PHE A 214PHE A 258 | None | 0.93A | 2vctC-2x2uA:undetectable | 2vctC-2x2uA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x7x | SENSOR PROTEIN (Bacteroidesthetaiotaomicron) |
PF13407(Peripla_BP_4) | 4 | ILE A 247GLY A 246LEU A 265LEU A 259 | None | 0.93A | 2vctC-2x7xA:2.1 | 2vctC-2x7xA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xs2 | DELETED INAZOOSPERMIA-LIKE (Mus musculus) |
PF00076(RRM_1) | 4 | GLY A 46LEU A 110PHE A 43PHE A 84 | NoneNone U B 4 ( 3.5A) U B 5 ( 3.5A) | 0.80A | 2vctC-2xs2A:undetectable | 2vctC-2xs2A:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypj | ENDOGLUCANASE CEL5A ([Eubacterium]cellulosolvens) |
no annotation | 4 | ILE A 705GLY A 704LEU A 622LEU A 624 | None | 0.86A | 2vctC-2ypjA:undetectable | 2vctC-2ypjA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a18 | ALDOXIME DEHYDRATASE (Rhodococcuserythropolis) |
PF13816(Dehydratase_hem) | 4 | TYR A 146ILE A 162GLY A 32LEU A 38 | None | 0.85A | 2vctC-3a18A:undetectable | 2vctC-3a18A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aje | PUTATIVEUNCHARACTERIZEDPROTEIN ST1526 (Sulfurisphaeratokodaii) |
PF01300(Sua5_yciO_yrdC)PF03481(SUA5) | 4 | TYR A 38ILE A 171GLY A 173LEU A 10 | None | 0.87A | 2vctC-3ajeA:undetectable | 2vctC-3ajeA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axx | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 4 | ILE A 240GLY A 237LEU A 287LEU A 292 | None | 0.62A | 2vctC-3axxA:undetectable | 2vctC-3axxA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9i | GITR LIGAND (Mus musculus) |
no annotation | 4 | TYR A 136ILE A 91GLY A 133LEU A 130 | None | 0.82A | 2vctC-3b9iA:undetectable | 2vctC-3b9iA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e79 | HIGH AFFINITYTRANSPORT SYSTEMPROTEIN P37 (Mycoplasmahyorhinis) |
PF06646(Mycoplasma_p37) | 4 | TYR A 162ILE A 336GLY A 165PHE A 243 | None | 0.90A | 2vctC-3e79A:undetectable | 2vctC-3e79A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eyk | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | ILE A 88GLY A 61LEU A 79LEU A 118 | None | 0.88A | 2vctC-3eykA:undetectable | 2vctC-3eykA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g04 | THYROTROPIN RECEPTOR (Homo sapiens) |
PF13306(LRR_5) | 4 | ILE C 158LEU C 207LEU C 213PHE C 189 | None | 0.92A | 2vctC-3g04C:undetectable | 2vctC-3g04C:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdh | TRIMETHYLGUANOSINESYNTHASE HOMOLOG (Homo sapiens) |
PF09445(Methyltransf_15) | 4 | LEU A 755LEU A 751PHE A 748PHE A 698 | NoneNoneNoneSAH A 854 (-4.3A) | 0.92A | 2vctC-3gdhA:undetectable | 2vctC-3gdhA:24.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gf5 | MAJOR VAULT PROTEIN (Mus musculus) |
PF01505(Vault) | 4 | ILE A 380GLY A 331LEU A 326LEU A 363 | None | 0.84A | 2vctC-3gf5A:undetectable | 2vctC-3gf5A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gon | PHOSPHOMEVALONATEKINASE (Streptococcuspneumoniae) |
PF00288(GHMP_kinases_N) | 4 | TYR A 11ILE A 18LEU A 139PHE A 132 | PMV A 400 (-4.0A)PMV A 400 (-4.6A)NoneNone | 0.86A | 2vctC-3gonA:undetectable | 2vctC-3gonA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1n | PROBABLE GLUTATHIONES-TRANSFERASE (Bordetellabronchiseptica) |
PF14497(GST_C_3) | 4 | TYR A 7ILE A 11GLY A 13ARG A 14 | NoneNone CL A 234 (-3.6A)None | 0.78A | 2vctC-3h1nA:4.9 | 2vctC-3h1nA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ieh | PUTATIVEMETALLOPEPTIDASE (Shewanellabaltica) |
PF04952(AstE_AspA) | 4 | ILE A 165GLY A 241LEU A 269PHE A 266 | None | 0.74A | 2vctC-3iehA:undetectable | 2vctC-3iehA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k92 | NAD-SPECIFICGLUTAMATEDEHYDROGENASE (Bacillussubtilis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | ILE A 248GLY A 249LEU A 291LEU A 292 | None | 0.81A | 2vctC-3k92A:undetectable | 2vctC-3k92A:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0w | ABC BRANCHED CHAINAMINO ACID FAMILYTRANSPORTER,PERIPLASMIC LIGANDBINDING PROTEIN (Paraburkholderiaxenovorans) |
PF13458(Peripla_BP_6) | 4 | GLY A 351LEU A 347LEU A 332PHE A 329 | None | 0.68A | 2vctC-3n0wA:undetectable | 2vctC-3n0wA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00365(PFK) | 4 | GLY A 729LEU A 718PHE A 696PHE A 693 | None | 0.89A | 2vctC-3o8oA:undetectable | 2vctC-3o8oA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sgg | HYPOTHETICALHYDROLASE (Bacteroidesthetaiotaomicron) |
PF14323(GxGYxYP_C)PF16216(GxGYxYP_N) | 4 | ILE A 147GLY A 172ARG A 171LEU A 92 | None | 0.61A | 2vctC-3sggA:undetectable | 2vctC-3sggA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sxf | CALMODULIN-DOMAINPROTEIN KINASE 1 (Toxoplasmagondii) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | ILE A 154LEU A 244LEU A 323PHE A 146 | None | 0.90A | 2vctC-3sxfA:1.1 | 2vctC-3sxfA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thz | DNA MISMATCH REPAIRPROTEIN MSH2 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | ILE A 685GLY A 683LEU A 310LEU A 312 | None | 0.94A | 2vctC-3thzA:undetectable | 2vctC-3thzA:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw8 | DENNDOMAIN-CONTAININGPROTEIN 1B (Homo sapiens) |
PF02141(DENN)PF03455(dDENN)PF03456(uDENN) | 4 | ILE A 227GLY A 247LEU A 206LEU A 203 | None | 0.88A | 2vctC-3tw8A:undetectable | 2vctC-3tw8A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw8 | DENNDOMAIN-CONTAININGPROTEIN 1B (Homo sapiens) |
PF02141(DENN)PF03455(dDENN)PF03456(uDENN) | 5 | ILE A 246GLY A 247LEU A 206LEU A 203PHE A 52 | None | 1.44A | 2vctC-3tw8A:undetectable | 2vctC-3tw8A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgf | MALTO-OLIGOSYLTREHALOSE TREHALOHYDROLASE (Sulfolobussolfataricus) |
PF00128(Alpha-amylase)PF09071(Alpha-amyl_C) | 5 | TYR A 397ILE A 473GLY A 420ARG A 387LEU A 465 | None | 1.16A | 2vctC-3vgfA:undetectable | 2vctC-3vgfA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqf | D-THREO-3-HYDROXYASPARTATE DEHYDRATASE (Delftia sp.HT23) |
PF01168(Ala_racemase_N)PF14031(D-ser_dehydrat) | 4 | ILE A 133GLY A 156ARG A 157LEU A 208 | None | 0.93A | 2vctC-3wqfA:undetectable | 2vctC-3wqfA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhh | NUCLEOPROTEIN (Californiaencephalitisorthobunyavirus) |
PF00952(Bunya_nucleocap) | 4 | ILE B 163GLY B 164LEU B 178LEU B 182 | None | 0.89A | 2vctC-4bhhB:undetectable | 2vctC-4bhhB:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhi | GAMMA-BUTYROBETAINEDIOXYGENASE (Homo sapiens) |
PF02668(TauD)PF06155(DUF971) | 4 | ILE A 289GLY A 234LEU A 320PHE A 317 | None | 0.72A | 2vctC-4bhiA:undetectable | 2vctC-4bhiA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dgj | ENTEROPEPTIDASECATALYTIC LIGHTCHAIN (Homo sapiens) |
PF00089(Trypsin) | 4 | ILE A 171GLY A 203LEU A 201LEU A 113 | None | 0.85A | 2vctC-4dgjA:undetectable | 2vctC-4dgjA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3e | CASA (Thermusthermophilus) |
PF09481(CRISPR_Cse1) | 4 | ILE A 15LEU A 158LEU A 157PHE A 7 | None | 0.84A | 2vctC-4f3eA:2.0 | 2vctC-4f3eA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ggv | CYTOCHROME P450SUPERFAMILY PROTEIN (Streptomyceshimastatinicus) |
PF00067(p450) | 4 | ILE A 273GLY A 356LEU A 128PHE A 364 | None | 0.87A | 2vctC-4ggvA:undetectable | 2vctC-4ggvA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3v | OXIDOREDUCTASEDOMAIN PROTEIN (Kribbellaflavida) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | ILE A 6GLY A 7LEU A 67LEU A 68 | None | 0.84A | 2vctC-4h3vA:undetectable | 2vctC-4h3vA:20.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hj2 | GLUTATHIONES-TRANSFERASE A1 (Homo sapiens) |
PF00043(GST_C)PF02798(GST_N) | 5 | TYR A 9GLY A 14ARG A 15LEU A 107LEU A 108 | LZ6 A 301 (-4.6A)LZ6 A 301 ( 3.9A)NoneLZ6 A 301 (-4.4A)None | 0.40A | 2vctC-4hj2A:36.0 | 2vctC-4hj2A:94.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lx4 | ENDOGLUCANASE(ENDO-1,4-BETA-GLUCANASE)PROTEIN (Pseudomonasstutzeri) |
PF00150(Cellulase) | 4 | TYR A 217ILE A 255GLY A 254LEU A 250 | None | 0.90A | 2vctC-4lx4A:undetectable | 2vctC-4lx4A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lzk | PIXA INCLUSION BODYPROTEIN (Burkholderiacenocepacia) |
PF12306(PixA) | 4 | ILE A 96GLY A 83LEU A 20LEU A 53 | None | 0.83A | 2vctC-4lzkA:undetectable | 2vctC-4lzkA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o5m | ISOVALERYL-COADEHYDROGENASE (Brucella suis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | ILE A 83GLY A 84PHE A 45PHE A 19 | None | 0.79A | 2vctC-4o5mA:undetectable | 2vctC-4o5mA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ogz | PUTATIVEALPHA-GALACTOSIDASE/MELIBIASE (Bacteroidesfragilis) |
PF10632(He_PIG_assoc)PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 4 | ILE A 322GLY A 318ARG A 308LEU A 305 | None | 0.67A | 2vctC-4ogzA:undetectable | 2vctC-4ogzA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opu | CONSERVED ARCHAEALPROTEIN (Sulfolobusacidocaldarius) |
PF01266(DAO) | 5 | GLY A 401ARG A 402LEU A 400LEU A 406PHE A 407 | None | 1.11A | 2vctC-4opuA:undetectable | 2vctC-4opuA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pcb | TRWC (Escherichiacoli) |
PF08751(TrwC) | 4 | GLY A 13ARG A 14LEU A 7PHE A 148 | None | 0.83A | 2vctC-4pcbA:undetectable | 2vctC-4pcbA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | ILE A3881GLY A3884ARG A3877LEU A3998 | None | 0.85A | 2vctC-4rh7A:undetectable | 2vctC-4rh7A:5.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1d | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT A (Saccharomycescerevisiae) |
no annotation | 4 | ILE C 58GLY C 59LEU C 68LEU C 72 | None | 0.87A | 2vctC-4u1dC:1.1 | 2vctC-4u1dC:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uer | EIF3A (Lachanceakluyveri) |
no annotation | 4 | ILE a 58GLY a 59LEU a 68LEU a 72 | None | 0.88A | 2vctC-4uera:4.1 | 2vctC-4uera:13.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwu | INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE,INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE (Eremotheciumgossypii) |
PF00478(IMPDH) | 4 | ILE A 94GLY A 250LEU A 271LEU A 300 | None | 0.76A | 2vctC-4xwuA:undetectable | 2vctC-4xwuA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ys4 | MEROZOITE SURFACEPROTEIN P41 (Plasmodiumfalciparum) |
PF07422(s48_45) | 4 | ILE A 52LEU A 87LEU A 86PHE A 109 | None | 0.84A | 2vctC-4ys4A:undetectable | 2vctC-4ys4A:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ze8 | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN(AGROCINOPINES A ANDB) (Agrobacteriumfabrum) |
PF00496(SBP_bac_5) | 4 | ILE A 488GLY A 329ARG A 477PHE A 332 | None | 0.81A | 2vctC-4ze8A:undetectable | 2vctC-4ze8A:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aga | DNA POLYMERASE THETA (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ILE A 789GLY A 788LEU A 728LEU A 725 | None | 0.93A | 2vctC-5agaA:undetectable | 2vctC-5agaA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cx8 | LIPOPROTEIN RAGB (Porphyromonasgingivalis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | ILE A 106GLY A 105LEU A 81PHE A 84 | None | 0.79A | 2vctC-5cx8A:1.0 | 2vctC-5cx8A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e3t | PHOSPHATIDYLINOSITOL-4-PHOSPHATE5-KINASE, TYPE I,ALPHA (Danio rerio) |
PF01504(PIP5K) | 4 | ILE A 376GLY A 375LEU A 224PHE A 203 | NoneNoneANP A 501 (-3.7A)None | 0.90A | 2vctC-5e3tA:undetectable | 2vctC-5e3tA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7q | ACYL-COA SYNTHETASE (Streptomycesplatensis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ILE A 360GLY A 393ARG A 394LEU A 404 | None | 0.71A | 2vctC-5e7qA:2.1 | 2vctC-5e7qA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gan | PRE-MRNA-PROCESSINGFACTOR 31 (Saccharomycescerevisiae) |
PF01798(Nop)PF09785(Prp31_C) | 4 | ILE F 214LEU F 84LEU F 80PHE F 54 | None | 0.90A | 2vctC-5ganF:undetectable | 2vctC-5ganF:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gvt | PLASMA KALLIKREIN (Mus musculus) |
no annotation | 4 | ILE A 181GLY A 211LEU A 209LEU A 123 | None | 0.86A | 2vctC-5gvtA:undetectable | 2vctC-5gvtA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) |
PF00067(p450) | 4 | ILE A 236GLY A 232LEU A 193LEU A 192 | None2OH A 402 ( 3.8A)NoneNone | 0.93A | 2vctC-5it1A:undetectable | 2vctC-5it1A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ixq | RECEPTOR-LIKEPROTEIN KINASE 5 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13855(LRR_8) | 5 | ILE A 458GLY A 482LEU A 506LEU A 511PHE A 487 | None | 1.35A | 2vctC-5ixqA:undetectable | 2vctC-5ixqA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ku1 | MITOCHONDRIAL RHOGTPASE 1 (Homo sapiens) |
PF08355(EF_assoc_1)PF08356(EF_assoc_2) | 5 | ILE A 192LEU A 204LEU A 209PHE A 212PHE A 217 | None | 1.43A | 2vctC-5ku1A:undetectable | 2vctC-5ku1A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ocm | NAD_GLY3P_DH,NAD-DEPENDENTGLYCEROL-3-PHOSPHATEDEHYDROGENASE (Streptosporangiumroseum) |
no annotation | 4 | ILE A 209LEU A 181LEU A 185PHE A 201 | None | 0.90A | 2vctC-5ocmA:undetectable | 2vctC-5ocmA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofb | MORC FAMILY CW-TYPEZINC FINGER PROTEIN2 (Homo sapiens) |
no annotation | 4 | ILE B 111GLY B 112LEU B 206PHE B 62 | None | 0.85A | 2vctC-5ofbB:2.5 | 2vctC-5ofbB:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x2q | TASTE RECEPTOR, TYPE1, MEMBER 2A (Oryzias latipes) |
PF01094(ANF_receptor) | 4 | ILE A 36GLY A 37LEU A 113LEU A 114 | None | 0.87A | 2vctC-5x2qA:undetectable | 2vctC-5x2qA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xp0 | PROBABLE CSGABOPERONTRANSCRIPTIONALREGULATORY PROTEIN (Salmonellaenterica) |
no annotation | 4 | ILE A 124LEU A 57LEU A 87PHE A 108 | None | 0.90A | 2vctC-5xp0A:undetectable | 2vctC-5xp0A:12.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxg | - (-) |
no annotation | 4 | TYR A 198ILE A 185GLY A 196LEU A 104 | None | 0.93A | 2vctC-5xxgA:undetectable | 2vctC-5xxgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ya1 | AUTOINDUCER-2 KINASE (Escherichiacoli) |
no annotation | 4 | GLY A 478LEU A 259LEU A 256PHE A 29 | None | 0.87A | 2vctC-5ya1A:undetectable | 2vctC-5ya1A:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c49 | ALCOHOLDEHYDROGENASE (Acinetobacterbaumannii) |
no annotation | 4 | ILE A 184GLY A 155LEU A 297LEU A 298 | None | 0.93A | 2vctC-6c49A:undetectable | 2vctC-6c49A:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0n | CLC-TYPEFLUORIDE/PROTONANTIPORTER (Enterococcuscasseliflavus) |
no annotation | 4 | TYR A 349ILE A 366LEU A 157PHE A 154 | None | 0.89A | 2vctC-6d0nA:undetectable | 2vctC-6d0nA:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eki | CARBONIC ANHYDRASE (Persephonellamarina) |
no annotation | 4 | ILE A 182GLY A 84PHE A 116PHE A 118 | None | 0.88A | 2vctC-6ekiA:undetectable | 2vctC-6ekiA:16.67 |