SIMILAR PATTERNS OF AMINO ACIDS FOR 2VCT_B_ASDB1223

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a4s BETAINE ALDEHYDE
DEHYDROGENASE

(Gadus morhua) 		PF00171
(Aldedh) 		4 ILE A 401
GLY A 403
LEU A 339
LEU A 345
 None
 0.73A 2vctB-1a4sA:
0.0		 2vctB-1a4sA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ar1 CYTOCHROME C OXIDASE

(Paracoccus
denitrificans) 		PF00116
(COX2)
PF02790
(COX2_TM) 		4 ILE B  92
GLY B  93
LEU B  97
LEU B 100
 None
LDA  B 274 ( 4.4A)
LDA  B 274 ( 4.4A)
None
 0.87A 2vctB-1ar1B:
0.0		 2vctB-1ar1B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlk THROMBIN HEAVY CHAIN

(Bos taurus) 		PF00089
(Trypsin) 		4 ILE B 181
GLY B 211
LEU B 209
LEU B 123
 None
 0.87A 2vctB-1dlkB:
0.0		 2vctB-1dlkB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ea9 CYCLOMALTODEXTRINASE

(Bacillus sp.
(in: Bacteria)) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 ILE C 314
GLY C 321
LEU C 236
PHE C 241
 None
 0.82A 2vctB-1ea9C:
0.0		 2vctB-1ea9C:
17.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gul GLUTATHIONE
TRANSFERASE A4-4

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   9
GLY A  14
ARG A  15
PHE A 111
 None
 0.56A 2vctB-1gulA:
33.4		 2vctB-1gulA:
54.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7w DIHYDROPYRIMIDINE
DEHYDROGENASE

(Sus scrofa) 		PF01180
(DHO_dh)
PF07992
(Pyr_redox_2)
PF14691
(Fer4_20)
PF14697
(Fer4_21) 		4 ILE A 796
GLY A 802
LEU A 806
PHE A 570
 None
 0.73A 2vctB-1h7wA:
1.2		 2vctB-1h7wA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyl HYPODERMA LINEATUM
COLLAGENASE

(Hypoderma
lineatum) 		PF00089
(Trypsin) 		4 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.79A 2vctB-1hylA:
undetectable		 2vctB-1hylA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0h NEOPULLULANASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 ILE A 508
LEU A 520
PHE A 445
PHE A 379
 None
 0.85A 2vctB-1j0hA:
0.0		 2vctB-1j0hA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m46 IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN
MYOSIN LIGHT CHAIN

(Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7)
no annotation 		4 ILE B 866
LEU A 126
PHE A 142
PHE A  90
 None
 0.90A 2vctB-1m46B:
undetectable		 2vctB-1m46B:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p43 ENOLASE 1

(Saccharomyces
cerevisiae) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 ILE A 185
GLY A 186
LEU A 151
PHE A 425
 None
 0.81A 2vctB-1p43A:
undetectable		 2vctB-1p43A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szq 2-METHYLCITRATE
DEHYDRATASE

(Escherichia
coli) 		PF03972
(MmgE_PrpD) 		4 ILE A 483
GLY A  78
LEU A  49
LEU A 447
 None
 0.87A 2vctB-1szqA:
undetectable		 2vctB-1szqA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tig TRANSLATION
INITIATION FACTOR 3

(Geobacillus
stearothermophilus) 		PF00707
(IF3_C) 		4 ILE A 132
GLY A 133
LEU A 137
LEU A 140
 None
 0.73A 2vctB-1tigA:
undetectable		 2vctB-1tigA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ya0 SMG-7 TRANSCRIPT
VARIANT 2

(Homo sapiens) 		PF10373
(EST1_DNA_bind)
PF10374
(EST1) 		4 ILE A 466
GLY A 463
LEU A 397
LEU A 396
 None
 0.63A 2vctB-1ya0A:
3.9		 2vctB-1ya0A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z9n SUPEROXIDE DISMUTASE
[CU-ZN]

([Haemophilus]
ducreyi) 		PF00080
(Sod_Cu) 		4 ILE A 176
LEU A 137
PHE A  55
PHE A  69
 None
 0.86A 2vctB-1z9nA:
undetectable		 2vctB-1z9nA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ILE A 258
GLY A 274
LEU A 280
LEU A 305
 None
 0.74A 2vctB-2b5mA:
undetectable		 2vctB-2b5mA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dej PROBABLE
GALACTOKINASE

(Pyrococcus
horikoshii) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg) 		4 ILE A  88
GLY A  87
LEU A  58
PHE A  75
 None
 0.68A 2vctB-2dejA:
undetectable		 2vctB-2dejA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f91 HEPATOPANCREAS
TRYPSIN

(Astacus
leptodactylus) 		PF00089
(Trypsin) 		4 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 CD  A 405 ( 4.9A)
None
None
None
 0.88A 2vctB-2f91A:
undetectable		 2vctB-2f91A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9f PEPTIDE N-GLYCANASE

(Mus musculus) 		PF04721
(PAW) 		5 ILE A 511
GLY A 517
LEU A 477
PHE A 478
PHE A 490
 None
None
None
GOL  A 103 ( 4.7A)
None
 1.41A 2vctB-2g9fA:
undetectable		 2vctB-2g9fA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnp TRANSCRIPTIONAL
REGULATOR

(Streptococcus
pneumoniae) 		PF04198
(Sugar-bind) 		4 ILE A 210
GLY A 209
LEU A 121
LEU A 124
 None
 0.78A 2vctB-2gnpA:
undetectable		 2vctB-2gnpA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi9 PLASMA SERINE
PROTEASE INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		4 ILE A 249
LEU A 363
LEU A 280
PHE A 275
 None
 0.87A 2vctB-2hi9A:
undetectable		 2vctB-2hi9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4l URIDYLATE KINASE

(Sulfolobus
solfataricus) 		PF00696
(AA_kinase) 		4 ILE A   4
GLY A  38
PHE A  98
PHE A 113
 None
 0.80A 2vctB-2j4lA:
undetectable		 2vctB-2j4lA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m3e INTEGRIN ALPHA-L

(Homo sapiens) 		PF00357
(Integrin_alpha) 		4 ILE A1073
GLY A1074
LEU A1078
LEU A1081
 None
 0.78A 2vctB-2m3eA:
undetectable		 2vctB-2m3eA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ncj UNCHARACTERIZED
PROTEIN

(Cronobacter
sakazakii) 		PF07445
(PriC) 		4 ILE A  21
GLY A  22
LEU A  46
LEU A  50
 None
 0.81A 2vctB-2ncjA:
2.4		 2vctB-2ncjA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfv EXOCYST COMPLEX
COMPONENT EXO70

(Saccharomyces
cerevisiae) 		PF03081
(Exo70) 		4 ILE A 472
GLY A 473
LEU A 477
LEU A 480
 None
 0.85A 2vctB-2pfvA:
4.9		 2vctB-2pfvA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpm CYTOKININ
DEHYDROGENASE 1

(Zea mays) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		4 ILE A 195
GLY A 227
LEU A 229
PHE A 401
 None
 0.79A 2vctB-2qpmA:
undetectable		 2vctB-2qpmA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN

(Salmonella
enterica) 		PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA) 		4 ILE A 609
LEU A 689
PHE A 693
PHE A 651
 None
 0.85A 2vctB-2qzaA:
2.8		 2vctB-2qzaA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5x UNCHARACTERIZED
CONSERVED PROTEIN

(Geobacillus
kaustophilus) 		PF08868
(YugN) 		4 ILE A  71
GLY A  57
ARG A  37
LEU A  74
 None
 0.78A 2vctB-2r5xA:
undetectable		 2vctB-2r5xA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vbk TAILSPIKE-PROTEIN

(Shigella virus
Sf6) 		PF12708
(Pectate_lyase_3) 		4 GLY A 405
LEU A 398
LEU A 396
PHE A 415
 None
 0.86A 2vctB-2vbkA:
undetectable		 2vctB-2vbkA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3m HYPOTHETICAL PROTEIN
ORF239

(Pyrobaculum
spherical virus) 		no annotation 4 ILE A 217
GLY A 218
ARG A 219
LEU A 227
 None
 0.90A 2vctB-2x3mA:
undetectable		 2vctB-2x3mA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xs2 DELETED IN
AZOOSPERMIA-LIKE

(Mus musculus) 		PF00076
(RRM_1) 		4 GLY A  46
LEU A 110
PHE A  43
PHE A  84
 None
None
U  B   4 ( 3.5A)
U  B   5 ( 3.5A)
 0.89A 2vctB-2xs2A:
undetectable		 2vctB-2xs2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a14 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Thermotoga
maritima) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 ILE A  15
GLY A  16
LEU A  20
LEU A  23
 NDP  A3001 (-4.3A)
None
None
NDP  A3003 ( 4.1A)
 0.89A 2vctB-3a14A:
undetectable		 2vctB-3a14A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axx 458AA LONG
HYPOTHETICAL
ENDO-1,4-BETA-GLUCAN
ASE

(Pyrococcus
horikoshii) 		PF00150
(Cellulase) 		4 ILE A 240
GLY A 237
LEU A 287
LEU A 292
 None
 0.69A 2vctB-3axxA:
undetectable		 2vctB-3axxA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9i GITR LIGAND

(Mus musculus) 		no annotation 4 TYR A 136
ILE A  91
GLY A 133
LEU A 130
 None
 0.81A 2vctB-3b9iA:
undetectable		 2vctB-3b9iA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37

(Mycoplasma
hyorhinis) 		PF06646
(Mycoplasma_p37) 		4 TYR A 162
ILE A 336
GLY A 165
PHE A 243
 None
 0.87A 2vctB-3e79A:
undetectable		 2vctB-3e79A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fkq NTRC-LIKE TWO-DOMAIN
PROTEIN

([Eubacterium]
rectale) 		PF13614
(AAA_31) 		4 ILE A 325
GLY A 326
LEU A 343
PHE A 129
 None
 0.68A 2vctB-3fkqA:
undetectable		 2vctB-3fkqA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g04 THYROTROPIN RECEPTOR

(Homo sapiens) 		PF13306
(LRR_5) 		4 ILE C 158
LEU C 207
LEU C 213
PHE C 189
 None
 0.85A 2vctB-3g04C:
undetectable		 2vctB-3g04C:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf5 MAJOR VAULT PROTEIN

(Mus musculus) 		PF01505
(Vault) 		4 ILE A 380
GLY A 331
LEU A 326
LEU A 363
 None
 0.84A 2vctB-3gf5A:
undetectable		 2vctB-3gf5A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE

(Bordetella
bronchiseptica) 		PF14497
(GST_C_3) 		4 TYR A   7
ILE A  11
GLY A  13
ARG A  14
 None
None
CL  A 234 (-3.6A)
None
 0.79A 2vctB-3h1nA:
20.7		 2vctB-3h1nA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1w MANNOSE-6-PHOSPHATE
ISOMERASE

(Salmonella
enterica) 		PF01238
(PMI_typeI) 		4 GLY A 276
LEU A 187
PHE A 184
PHE A 148
 EDO  A 393 ( 3.7A)
EDO  A 394 ( 4.0A)
EDO  A 394 (-4.3A)
None
 0.72A 2vctB-3h1wA:
undetectable		 2vctB-3h1wA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjz TRANSALDOLASE B

(Prochlorococcus
marinus) 		PF00923
(TAL_FSA) 		4 ILE A  92
GLY A  94
ARG A  95
LEU A 244
 None
 0.82A 2vctB-3hjzA:
undetectable		 2vctB-3hjzA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3y CARBOHYDRATE KINASE

(Klebsiella
pneumoniae) 		PF00294
(PfkB) 		4 GLY A   7
LEU A  56
LEU A  80
PHE A  86
 None
 0.90A 2vctB-3i3yA:
undetectable		 2vctB-3i3yA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ieh PUTATIVE
METALLOPEPTIDASE

(Shewanella
baltica) 		PF04952
(AstE_AspA) 		4 ILE A 165
GLY A 241
LEU A 269
PHE A 266
 None
 0.72A 2vctB-3iehA:
undetectable		 2vctB-3iehA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luy PROBABLE CHORISMATE
MUTASE

(Bifidobacterium
adolescentis) 		PF00800
(PDT) 		4 ILE A  46
GLY A  57
LEU A   6
LEU A  37
 None
 0.89A 2vctB-3luyA:
undetectable		 2vctB-3luyA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		4 TYR A 108
GLY A 352
LEU A 347
PHE A 324
 LEU  A 601 (-4.5A)
NA  A 751 ( 4.8A)
None
None
 0.89A 2vctB-3mpnA:
undetectable		 2vctB-3mpnA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mw4 NEUREXIN-2-BETA

(Mus musculus) 		PF02210
(Laminin_G_2) 		4 ILE A 123
GLY A 215
LEU A  93
LEU A  95
 None
 0.88A 2vctB-3mw4A:
undetectable		 2vctB-3mw4A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
elegans) 		PF02373
(JmjC) 		4 GLY A 579
LEU A 484
LEU A 423
PHE A 498
 None
None
OGA  A   4 (-4.4A)
None
 0.75A 2vctB-3n9oA:
5.0		 2vctB-3n9oA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njp EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 ILE A 143
LEU A  80
LEU A  77
PHE A 126
 None
 0.80A 2vctB-3njpA:
undetectable		 2vctB-3njpA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1

(Anopheles
gambiae) 		PF00560
(LRR_1) 		4 ILE A 203
LEU A 173
LEU A 171
PHE A 183
 None
 0.80A 2vctB-3ojaA:
undetectable		 2vctB-3ojaA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5w L-ORNITHINE
5-MONOOXYGENASE

(Pseudomonas
aeruginosa) 		PF13434
(K_oxygenase) 		4 ILE A 419
LEU A 412
LEU A  71
PHE A  43
 None
 0.85A 2vctB-3s5wA:
undetectable		 2vctB-3s5wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgg HYPOTHETICAL
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF14323
(GxGYxYP_C)
PF16216
(GxGYxYP_N) 		4 ILE A 147
GLY A 172
ARG A 171
LEU A  92
 None
 0.73A 2vctB-3sggA:
undetectable		 2vctB-3sggA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0o SELENIDE, WATER
DIKINASE

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 182
GLY A 181
LEU A 295
LEU A 296
 None
 0.70A 2vctB-3u0oA:
undetectable		 2vctB-3u0oA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u2r REGULATORY PROTEIN
MARR

(Planctopirus
limnophila) 		PF01047
(MarR) 		4 GLY A  87
ARG A  86
LEU A  88
LEU A 112
 None
 0.82A 2vctB-3u2rA:
undetectable		 2vctB-3u2rA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubu AGGLUCETIN SUBUNIT
BETA-2

(Deinagkistrodon
acutus) 		PF00059
(Lectin_C) 		4 ILE B  66
GLY B 101
LEU B  99
LEU B  70
 None
 0.84A 2vctB-3ubuB:
undetectable		 2vctB-3ubuB:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF09071
(Alpha-amyl_C) 		5 TYR A 397
ILE A 473
GLY A 420
ARG A 387
LEU A 465
 None
 1.19A 2vctB-3vgfA:
undetectable		 2vctB-3vgfA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6m 458AA LONG
HYPOTHETICAL
ENDO-1,4-BETA-GLUCAN
ASE

(Pyrococcus
horikoshii) 		PF00150
(Cellulase) 		4 ILE A 240
GLY A 237
LEU A 287
LEU A 292
 None
 0.71A 2vctB-3w6mA:
undetectable		 2vctB-3w6mA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7x PROBABLE
OXIDOREDUCTASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 GLY A  99
LEU A  46
LEU A 332
PHE A  24
 None
 0.84A 2vctB-4b7xA:
undetectable		 2vctB-4b7xA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE

(Homo sapiens) 		PF02668
(TauD)
PF06155
(DUF971) 		4 ILE A 289
GLY A 234
LEU A 320
PHE A 317
 None
 0.64A 2vctB-4bhiA:
undetectable		 2vctB-4bhiA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dgj ENTEROPEPTIDASE
CATALYTIC LIGHT
CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 ILE A 171
GLY A 203
LEU A 201
LEU A 113
 None
 0.83A 2vctB-4dgjA:
undetectable		 2vctB-4dgjA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffl PYLC

(Methanosarcina
barkeri) 		PF02655
(ATP-grasp_3) 		4 ILE A 322
ARG A 348
LEU A 352
LEU A 363
 None
 0.88A 2vctB-4fflA:
undetectable		 2vctB-4fflA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxw ADENOSINE DEAMINASE

(Burkholderia
ambifaria) 		PF00962
(A_deaminase) 		4 TYR A  66
ILE A  62
LEU A  82
LEU A  87
 None
 0.70A 2vctB-4gxwA:
undetectable		 2vctB-4gxwA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzu FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 719
ARG A 631
LEU A 627
PHE A 592
 None
 0.88A 2vctB-4gzuA:
3.6		 2vctB-4gzuA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3v OXIDOREDUCTASE
DOMAIN PROTEIN

(Kribbella
flavida) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 ILE A   6
GLY A   7
LEU A  67
LEU A  68
 None
 0.87A 2vctB-4h3vA:
undetectable		 2vctB-4h3vA:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hj2 GLUTATHIONE
S-TRANSFERASE A1

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		5 TYR A   9
GLY A  14
ARG A  15
LEU A 107
LEU A 108
 LZ6  A 301 (-4.6A)
LZ6  A 301 ( 3.9A)
None
LZ6  A 301 (-4.4A)
None
 0.44A 2vctB-4hj2A:
35.8		 2vctB-4hj2A:
94.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC

(Solanum
lycopersicum) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 ILE A 459
GLY A 469
LEU A 542
LEU A 452
 None
 0.90A 2vctB-4ksiA:
2.1		 2vctB-4ksiA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kw2 UNCHARACTERIZED
PROTEIN

(Parabacteroides
distasonis) 		PF01261
(AP_endonuc_2) 		4 ILE A  32
GLY A  31
LEU A 244
PHE A  91
 None
 0.90A 2vctB-4kw2A:
undetectable		 2vctB-4kw2A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgi UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		PF13678
(Peptidase_M85) 		4 ILE A  76
GLY A  77
LEU A  81
LEU A  84
 None
 0.87A 2vctB-4lgiA:
undetectable		 2vctB-4lgiA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN

(Pseudomonas
stutzeri) 		PF00150
(Cellulase) 		4 TYR A 217
ILE A 255
GLY A 254
LEU A 250
 None
 0.89A 2vctB-4lx4A:
undetectable		 2vctB-4lx4A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lzk PIXA INCLUSION BODY
PROTEIN

(Burkholderia
cenocepacia) 		PF12306
(PixA) 		4 ILE A  96
GLY A  83
LEU A  20
LEU A  53
 None
 0.86A 2vctB-4lzkA:
undetectable		 2vctB-4lzkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM4
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM8

(Saccharomyces
cerevisiae) 		PF01423
(LSM) 		4 ILE G  86
LEU G  81
LEU A  55
PHE A  37
 None
 0.88A 2vctB-4m7aG:
undetectable		 2vctB-4m7aG:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6f PUTATIVE THIOSUGAR
SYNTHASE

(Amycolatopsis
orientalis) 		PF05690
(ThiG) 		4 ILE A  52
GLY A  82
LEU A 109
LEU A 111
 None
 0.90A 2vctB-4n6fA:
undetectable		 2vctB-4n6fA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ogz PUTATIVE
ALPHA-GALACTOSIDASE/
MELIBIASE

(Bacteroides
fragilis) 		PF10632
(He_PIG_assoc)
PF16499
(Melibiase_2)
PF17450
(Melibiase_2_C) 		4 ILE A 322
GLY A 318
ARG A 308
LEU A 305
 None
 0.65A 2vctB-4ogzA:
undetectable		 2vctB-4ogzA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9n CARBOXYLESTERASE

(Sulfolobus
shibatae) 		PF07859
(Abhydrolase_3) 		4 ILE A  49
LEU A 136
PHE A 139
PHE A  64
 None
 0.86A 2vctB-4p9nA:
undetectable		 2vctB-4p9nA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdh VARIABLE LYMPHOCYTE
RECEPTOR B,
TOLL-LIKE RECEPTOR 9
CHIMERA

(Eptatretus
burgeri;
Mus musculus) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13306
(LRR_5)
PF13855
(LRR_8) 		4 ILE A 293
LEU A 264
LEU A 262
PHE A 301
 None
 0.87A 2vctB-4qdhA:
undetectable		 2vctB-4qdhA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcw SLIT AND NTRK-LIKE
PROTEIN 1

(Homo sapiens) 		PF13855
(LRR_8) 		4 ILE A 350
GLY A 354
LEU A 401
PHE A 381
 None
 0.86A 2vctB-4rcwA:
undetectable		 2vctB-4rcwA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 ILE A3881
GLY A3884
ARG A3877
LEU A3998
 None
 0.83A 2vctB-4rh7A:
undetectable		 2vctB-4rh7A:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryb 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Neisseria
meningitidis) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ILE A   6
GLY A   8
LEU A 137
PHE A 117
 None
 0.85A 2vctB-4rybA:
undetectable		 2vctB-4rybA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s2t PROTEIN APP-1

(Caenorhabditis
elegans) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		4 TYR P 531
ILE P 533
LEU P 479
LEU P 477
 None
 0.87A 2vctB-4s2tP:
undetectable		 2vctB-4s2tP:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ys4 MEROZOITE SURFACE
PROTEIN P41

(Plasmodium
falciparum) 		PF07422
(s48_45) 		4 ILE A  52
LEU A  87
LEU A  86
PHE A 109
 None
 0.79A 2vctB-4ys4A:
undetectable		 2vctB-4ys4A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ze8 ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN
(AGROCINOPINES A AND
B)

(Agrobacterium
fabrum) 		PF00496
(SBP_bac_5) 		4 ILE A 488
GLY A 329
ARG A 477
PHE A 332
 None
 0.76A 2vctB-4ze8A:
undetectable		 2vctB-4ze8A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT

(Candidatus
Kuenenia
stuttgartiensis) 		no annotation 4 ILE A 236
GLY A 235
LEU A 233
PHE A 195
 None
 0.82A 2vctB-5c2vA:
undetectable		 2vctB-5c2vA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cx8 LIPOPROTEIN RAGB

(Porphyromonas
gingivalis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ILE A 106
GLY A 105
LEU A  81
PHE A  84
 None
 0.80A 2vctB-5cx8A:
2.3		 2vctB-5cx8A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djs TETRATRICOPEPTIDE
TPR_2 REPEAT PROTEIN

(Thermobaculum
terrenum) 		PF13181
(TPR_8)
PF13844
(Glyco_transf_41) 		4 ILE A 410
GLY A 334
LEU A 362
LEU A 392
 None
 0.85A 2vctB-5djsA:
undetectable		 2vctB-5djsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7q ACYL-COA SYNTHETASE

(Streptomyces
platensis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 ILE A 360
GLY A 393
ARG A 394
LEU A 404
 None
 0.66A 2vctB-5e7qA:
undetectable		 2vctB-5e7qA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvt PLASMA KALLIKREIN

(Mus musculus) 		no annotation 4 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.83A 2vctB-5gvtA:
undetectable		 2vctB-5gvtA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ixq RECEPTOR-LIKE
PROTEIN KINASE 5

(Arabidopsis
thaliana) 		PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 ILE A 458
LEU A 506
LEU A 511
PHE A 487
 None
 0.87A 2vctB-5ixqA:
undetectable		 2vctB-5ixqA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1t TORSIN-1A

(Homo sapiens) 		PF06309
(Torsin) 		4 ILE A 155
LEU A 131
PHE A 132
PHE A 138
 None
 0.86A 2vctB-5j1tA:
undetectable		 2vctB-5j1tA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k7l POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 1

(Rattus
norvegicus) 		PF00027
(cNMP_binding)
PF00520
(Ion_trans)
PF13426
(PAS_9) 		4 ILE A 373
GLY A 374
LEU A 392
LEU A 395
 None
 0.78A 2vctB-5k7lA:
2.1		 2vctB-5k7lA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktz VP1

(Enterovirus C) 		PF00073
(Rhv) 		4 TYR 1 159
ILE 1 110
GLY 1 238
PHE 1 130
 None
 0.85A 2vctB-5ktz1:
undetectable		 2vctB-5ktz1:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ku1 MITOCHONDRIAL RHO
GTPASE 1

(Homo sapiens) 		PF08355
(EF_assoc_1)
PF08356
(EF_assoc_2) 		5 ILE A 192
LEU A 204
LEU A 209
PHE A 212
PHE A 217
 None
 1.33A 2vctB-5ku1A:
undetectable		 2vctB-5ku1A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfg PROCARDOSIN-B,PROCAR
DOSIN-B

(Cynara
cardunculus) 		no annotation 4 GLY A 316
LEU A 319
PHE A 320
PHE A 362
 None
 0.89A 2vctB-5nfgA:
undetectable		 2vctB-5nfgA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5va3 POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 2

(Homo sapiens) 		PF00027
(cNMP_binding)
PF00520
(Ion_trans)
PF13426
(PAS_9) 		4 ILE A 571
GLY A 572
LEU A 586
LEU A 589
 None
 0.68A 2vctB-5va3A:
undetectable		 2vctB-5va3A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA

(Thermus
thermophilus) 		no annotation 4 ILE A 128
GLY A 129
LEU A 136
PHE A  54
 None
 0.83A 2vctB-5vkvA:
undetectable		 2vctB-5vkvA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xl2 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 ILE A 227
GLY A 178
LEU A 248
LEU A 150
 None
 0.88A 2vctB-5xl2A:
undetectable		 2vctB-5xl2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwu LEUCINE-RICH REPEAT
AND FIBRONECTIN TYPE
III
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		no annotation 4 ILE B 149
LEU B 120
LEU B 118
PHE B 157
 None
 0.81A 2vctB-5xwuB:
undetectable		 2vctB-5xwuB:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ya1 AUTOINDUCER-2 KINASE

(Escherichia
coli) 		no annotation 4 GLY A 478
LEU A 259
LEU A 256
PHE A  29
 None
 0.90A 2vctB-5ya1A:
undetectable		 2vctB-5ya1A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 ILE A 714
LEU A 685
LEU A 683
PHE A 722
 None
 0.90A 2vctB-5zlnA:
undetectable		 2vctB-5zlnA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a8m -

(-) 		no annotation 4 GLY A  72
ARG A  20
LEU A  96
PHE A  12
 None
 0.69A 2vctB-6a8mA:
undetectable		 2vctB-6a8mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az1 RIBOSOMAL PROTEIN
S4E

(Leishmania
donovani) 		no annotation 4 ILE E  61
GLY E  58
ARG E  46
LEU E  42
 None
None
G  1 491 ( 2.9A)
None
 0.88A 2vctB-6az1E:
undetectable		 2vctB-6az1E:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0n CLC-TYPE
FLUORIDE/PROTON
ANTIPORTER

(Enterococcus
casseliflavus) 		no annotation 4 TYR A 349
ILE A 366
LEU A 157
PHE A 154
 None
 0.86A 2vctB-6d0nA:
undetectable		 2vctB-6d0nA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eki CARBONIC ANHYDRASE

(Persephonella
marina) 		no annotation 4 ILE A 182
GLY A  84
PHE A 116
PHE A 118
 None
 0.62A 2vctB-6ekiA:
undetectable		 2vctB-6ekiA:
16.67