SIMILAR PATTERNS OF AMINO ACIDS FOR 2VAX_F_CSCF1384_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ad3 | ALDEHYDEDEHYDROGENASE (CLASS3) (Rattusnorvegicus) |
PF00171(Aldedh) | 5 | LEU A 119THR A 186TYR A 412LYS A 416HIS A 413 | None | 1.44A | 2vaxF-1ad3A:0.8 | 2vaxF-1ad3A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v47 | ATP SULFURYLASE (Thermusthermophilus) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | LEU A 16THR A 228ARG A 231PHE A 32MET A 33 | None | 1.43A | 2vaxF-1v47A:0.8 | 2vaxF-1v47A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b61 | HOMOSERINEO-ACETYLTRANSFERASE (Haemophilusinfluenzae) |
PF00561(Abhydrolase_1) | 5 | LEU A 49THR A 50ARG A 212TYR A 219GLN A 253 | None | 1.14A | 2vaxF-2b61A:43.3 | 2vaxF-2b61A:28.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b61 | HOMOSERINEO-ACETYLTRANSFERASE (Haemophilusinfluenzae) |
PF00561(Abhydrolase_1) | 6 | LEU A 49THR A 50ARG A 212TYR A 219HIS A 337PHE A 340 | None | 0.70A | 2vaxF-2b61A:43.3 | 2vaxF-2b61A:28.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b61 | HOMOSERINEO-ACETYLTRANSFERASE (Haemophilusinfluenzae) |
PF00561(Abhydrolase_1) | 6 | LEU A 49THR A 50TYR A 219TYR A 249HIS A 337PHE A 340 | None | 0.86A | 2vaxF-2b61A:43.3 | 2vaxF-2b61A:28.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 5 | LEU A 340TYR A 131GLN A 135HIS A 127PHE A 170 | None | 1.29A | 2vaxF-2c3oA:0.7 | 2vaxF-2c3oA:15.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2vat | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE (Acremoniumchrysogenum) |
PF00561(Abhydrolase_1) | 5 | ARG A 218TYR A 225HIS A 362PHE A 365MET A 367 | COA A1383 (-3.8A)COA A1383 (-4.1A)COA A1383 ( 4.6A)NoneCOA A1383 (-3.6A) | 0.97A | 2vaxF-2vatA:58.4 | 2vaxF-2vatA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2vat | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE (Acremoniumchrysogenum) |
PF00561(Abhydrolase_1) | 9 | THR A 58LEU A 59THR A 60TYR A 225LYS A 226ARG A 234HIS A 362PHE A 365MET A 367 | COA A1383 ( 4.1A)NoneCOA A1383 ( 4.9A)COA A1383 (-4.1A)COA A1383 (-2.8A)COA A1383 (-3.8A)COA A1383 ( 4.6A)NoneCOA A1383 (-3.6A) | 0.75A | 2vaxF-2vatA:58.4 | 2vaxF-2vatA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2vat | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE (Acremoniumchrysogenum) |
PF00561(Abhydrolase_1) | 9 | THR A 58LEU A 59THR A 60TYR A 225LYS A 226GLN A 281HIS A 362PHE A 365MET A 367 | COA A1383 ( 4.1A)NoneCOA A1383 ( 4.9A)COA A1383 (-4.1A)COA A1383 (-2.8A)COA A1383 (-4.0A)COA A1383 ( 4.6A)NoneCOA A1383 (-3.6A) | 0.70A | 2vaxF-2vatA:58.4 | 2vaxF-2vatA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2vat | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE (Acremoniumchrysogenum) |
PF00561(Abhydrolase_1) | 9 | THR A 58LEU A 59THR A 60TYR A 225LYS A 226TYR A 277HIS A 362PHE A 365MET A 367 | COA A1383 ( 4.1A)NoneCOA A1383 ( 4.9A)COA A1383 (-4.1A)COA A1383 (-2.8A)COA A1383 (-4.4A)COA A1383 ( 4.6A)NoneCOA A1383 (-3.6A) | 0.44A | 2vaxF-2vatA:58.4 | 2vaxF-2vatA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vvl | HOMOSERINEO-ACETYLTRANSFERASE (Streptomyceslavendulae) |
PF00561(Abhydrolase_1) | 6 | LEU A 53ARG A 218TYR A 225ARG A 234HIS A 352PHE A 355 | None | 0.74A | 2vaxF-3vvlA:45.5 | 2vaxF-3vvlA:31.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vvl | HOMOSERINEO-ACETYLTRANSFERASE (Streptomyceslavendulae) |
PF00561(Abhydrolase_1) | 6 | LEU A 53ARG A 218TYR A 225TYR A 260HIS A 352PHE A 355 | None | 0.84A | 2vaxF-3vvlA:45.5 | 2vaxF-3vvlA:31.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w8o | HOMOSERINEO-ACETYLTRANSFERASE (Mycolicibacteriumhassiacum) |
PF00561(Abhydrolase_1) | 8 | LEU A 60THR A 61ARG A 227TYR A 234ARG A 243GLN A 269HIS A 350PHE A 353 | None | 0.98A | 2vaxF-5w8oA:45.8 | 2vaxF-5w8oA:33.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w8o | HOMOSERINEO-ACETYLTRANSFERASE (Mycolicibacteriumhassiacum) |
PF00561(Abhydrolase_1) | 8 | LEU A 60THR A 61ARG A 227TYR A 234ARG A 243TYR A 265HIS A 350PHE A 353 | None | 0.91A | 2vaxF-5w8oA:45.8 | 2vaxF-5w8oA:33.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 7 | LEU A 63THR A 64ARG A 230TYR A 237ARG A 246GLN A 276HIS A 357 | None | 0.92A | 2vaxF-5w8pA:46.3 | 2vaxF-5w8pA:32.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 7 | LEU A 63THR A 64ARG A 230TYR A 237ARG A 246TYR A 272HIS A 357 | None | 0.87A | 2vaxF-5w8pA:46.3 | 2vaxF-5w8pA:32.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 7 | LEU A 63THR A 64ARG A 230TYR A 237GLN A 276HIS A 357PHE A 360 | None | 0.83A | 2vaxF-5w8pA:46.3 | 2vaxF-5w8pA:32.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 7 | LEU A 63THR A 64ARG A 230TYR A 237TYR A 272HIS A 357PHE A 360 | None | 0.71A | 2vaxF-5w8pA:46.3 | 2vaxF-5w8pA:32.95 |