SIMILAR PATTERNS OF AMINO ACIDS FOR 2V7U_B_SAMB1300_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wu8 | HYPOTHETICAL PROTEINPH0463 (Pyrococcushorikoshii) |
PF01887(SAM_adeno_trans) | 6 | ASP A 179PHE A 181ASN A 183SER A 226ALA A 233ASN A 235 | None | 1.09A | 2v7uC-1wu8A:26.8 | 2v7uC-1wu8A:28.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c4t | 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE (Streptomycescattleya) |
PF01887(SAM_adeno_trans) | 9 | ASP A 210PHE A 213ASN A 215TRP A 217PHE A 254SER A 269ARG A 270ALA A 276ASN A 278 | None | 0.20A | 2v7uC-2c4tA:46.9 | 2v7uC-2c4tA:99.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cw5 | BACTERIALFLUORINATING ENZYMEHOMOLOG (Thermusthermophilus) |
PF01887(SAM_adeno_trans) | 6 | ASP A 182PHE A 184ASN A 186SER A 227ALA A 234ASN A 236 | None | 0.91A | 2v7uC-2cw5A:23.2 | 2v7uC-2cw5A:29.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q6k | CHLORINASE (Salinisporatropica) |
PF01887(SAM_adeno_trans) | 7 | ASP A 183PHE A 186ASN A 188TRP A 190PHE A 228SER A 242ASN A 251 | PEG A 402 (-2.9A)NoneNoneNoneNonePEG A 402 (-3.3A)None | 0.77A | 2v7uC-2q6kA:31.5 | 2v7uC-2q6kA:38.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbv | UNCHARACTERIZEDCONSERVED PROTEIN (Thermotogamaritima) |
PF01887(SAM_adeno_trans) | 7 | ASP A 178PHE A 180ASN A 182PHE A 220SER A 234ALA A 241ASN A 243 | None | 0.86A | 2v7uC-2zbvA:30.6 | 2v7uC-2zbvA:29.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzh | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcuspyogenes) |
PF09704(Cas_Cas5d) | 5 | PHE A 101ASN A 55PHE A 99SER A 126ARG A 132 | None | 1.14A | 2v7uC-3vzhA:0.0 | 2v7uC-3vzhA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0j | UNCHARACTERIZEDPROTEIN (Streptococcusmutans) |
PF09704(Cas_Cas5d) | 5 | PHE A 103ASN A 57PHE A 101SER A 128ARG A 134 | NoneNoneNoneSO4 A 303 ( 4.7A)SO4 A 303 (-4.1A) | 1.20A | 2v7uC-4r0jA:0.0 | 2v7uC-4r0jA:21.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmz | FLUORINASE (Streptomycessp. MA37) |
PF01887(SAM_adeno_trans) | 8 | ASP A 210PHE A 213ASN A 215TRP A 217PHE A 254SER A 269ALA A 276ASN A 278 | None1DA A 301 (-3.0A)1DA A 301 (-2.0A)None1DA A 301 (-3.3A)None1DA A 301 (-3.0A)1DA A 301 ( 4.4A) | 0.35A | 2v7uC-5lmzA:42.9 | 2v7uC-5lmzA:87.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmz | FLUORINASE (Streptomycessp. MA37) |
PF01887(SAM_adeno_trans) | 8 | ASP A 210PHE A 213ASN A 215TRP A 217PHE A 254SER A 269ARG A 270ALA A 276 | None1DA A 301 (-3.0A)1DA A 301 (-2.0A)None1DA A 301 (-3.3A)NoneNone1DA A 301 (-3.0A) | 0.69A | 2v7uC-5lmzA:42.9 | 2v7uC-5lmzA:87.00 |