SIMILAR PATTERNS OF AMINO ACIDS FOR 2V57_C_PRLC1187

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bvy PROTEIN (CYTOCHROME
P450 BM-3)

(Bacillus
megaterium) 		PF00258
(Flavodoxin_1) 		4 SER F 565
ASN F 596
ILE F 597
ASP F 623
 None
 1.11A 2v57C-1bvyF:
undetectable		 2v57C-1bvyF:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE

(Providencia
rettgeri;
Providencia
rettgeri) 		PF01804
(Penicil_amidase)
PF01804
(Penicil_amidase) 		4 ASN A 148
ILE B  77
ASP B  76
ARG B 199
 CA  B 554 ( 4.9A)
None
CA  B 554 (-3.7A)
None
 1.10A 2v57C-1cp9A:
undetectable		 2v57C-1cp9A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dpp DIPEPTIDE BINDING
PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ILE A 157
ASP A  89
ARG A  83
TRP A  73
 None
 0.92A 2v57C-1dppA:
0.0		 2v57C-1dppA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dt2 EXFOLIATIVE TOXIN B

(Staphylococcus
aureus) 		PF13365
(Trypsin_2) 		4 HIS A  27
SER A 163
ASN A  84
ASP A  86
 None
 1.07A 2v57C-1dt2A:
undetectable		 2v57C-1dt2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanosarcina
barkeri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 SER B2177
ASN B2181
ILE B2178
ASP B2166
 None
 1.03A 2v57C-1e6yB:
0.0		 2v57C-1e6yB:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lf9 GLUCOAMYLASE

(Thermoanaerobacterium
thermosaccharolyticum) 		PF00723
(Glyco_hydro_15)
PF09137
(Glucodextran_N) 		4 HIS A 222
SER A 200
ILE A 209
ASP A 212
 None
 1.07A 2v57C-1lf9A:
0.0		 2v57C-1lf9A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qil TOXIC SHOCK SYNDROME
TOXIN-1

(Staphylococcus
aureus) 		PF02876
(Stap_Strp_tox_C) 		4 ILE A 126
ASP A 130
ARG A 134
TRP A 154
 None
 1.05A 2v57C-1qilA:
undetectable		 2v57C-1qilA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qox BETA-GLUCOSIDASE

(Bacillus
circulans) 		PF00232
(Glyco_hydro_1) 		4 SER A 365
ILE A 370
ASP A 362
ARG A 374
 None
 1.01A 2v57C-1qoxA:
0.0		 2v57C-1qoxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 ILE A 321
TYR A 222
ASP A 320
ARG A  67
 None
 1.04A 2v57C-1r8wA:
0.3		 2v57C-1r8wA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smq RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SMALL CHAIN 1

(Saccharomyces
cerevisiae) 		PF00268
(Ribonuc_red_sm) 		4 SER A 265
ASN A 266
ILE A 269
TYR A 190
 None
 1.13A 2v57C-1smqA:
0.0		 2v57C-1smqA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tq1 SENESCENCE-ASSOCIATE
D FAMILY PROTEIN

(Arabidopsis
thaliana) 		PF00581
(Rhodanese) 		4 SER A  95
ILE A  96
TYR A  57
ASP A 112
 None
 1.13A 2v57C-1tq1A:
undetectable		 2v57C-1tq1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjs ALPHA-AMYLASE

(Bacillus
licheniformis) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 ASN A 104
ILE A 236
TYR A  46
ARG A 229
 None
 0.91A 2v57C-1vjsA:
0.0		 2v57C-1vjsA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xv5 DNA
ALPHA-GLUCOSYLTRANSF
ERASE

(Escherichia
virus T4) 		PF11440
(AGT) 		5 HIS A1114
SER A1020
ASN A1081
ILE A1005
TYR A1307
 GOL  A2002 (-3.6A)
None
None
None
UDP  A1402 (-4.7A)
 1.49A 2v57C-1xv5A:
undetectable		 2v57C-1xv5A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq2 BETA-GALACTOSIDASE

(Arthrobacter
sp. C2-2) 		PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 HIS A 335
SER A 368
ASP A 201
TRP A 552
 PEG  A9001 (-4.3A)
None
NA  A7501 (-2.7A)
NA  A7501 (-4.7A)
 1.00A 2v57C-1yq2A:
undetectable		 2v57C-1yq2A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2efe SIMILARITY TO
VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN VPS9

(Arabidopsis
thaliana) 		PF02204
(VPS9) 		4 SER A  97
ASN A  98
TYR A 213
ASP A  42
 None
 1.03A 2v57C-2efeA:
undetectable		 2v57C-2efeA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fuv PHOSPHOGLUCOMUTASE

(Salmonella
enterica) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ASN A 131
ILE A 127
ASP A 139
ARG A  72
 None
 0.96A 2v57C-2fuvA:
undetectable		 2v57C-2fuvA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT

(Thermus
thermophilus) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 SER A 452
ILE A 451
ASP A 700
ARG A 703
 None
 1.09A 2v57C-2ipcA:
undetectable		 2v57C-2ipcA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixd LMBE-RELATED PROTEIN

(Bacillus cereus) 		PF02585
(PIG-L) 		4 HIS A 113
ILE A  18
ASP A  14
ARG A  53
 ZN  A1234 ( 3.2A)
None
ACT  A1235 (-2.8A)
ACT  A1235 (-4.6A)
 1.06A 2v57C-2ixdA:
undetectable		 2v57C-2ixdA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ong 4S-LIMONENE SYNTHASE

(Mentha spicata) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 HIS A 579
ILE A 348
TYR A 573
ASP A 352
 FPG  A 600 (-3.3A)
FPG  A 600 (-4.5A)
None
FPG  A 600 (-2.8A)
 1.12A 2v57C-2ongA:
2.0		 2v57C-2ongA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vn7 GLUCOAMYLASE

(Trichoderma
reesei) 		PF00686
(CBM_20)
PF00723
(Glyco_hydro_15) 		4 HIS A 418
ASN A  16
ILE A  12
ASP A 399
 None
 1.07A 2v57C-2vn7A:
undetectable		 2v57C-2vn7A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wn4 ADP-RIBOSYLTRANSFERA
SE ENZYMATIC
COMPONENT

(Clostridioides
difficile) 		PF03496
(ADPrib_exo_Tox) 		4 ASN A 263
ILE A 266
TYR A 253
ARG A 302
 None
 1.05A 2v57C-2wn4A:
undetectable		 2v57C-2wn4A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0f WSAF

(Geobacillus
stearothermophilus) 		no annotation 4 SER A 202
ASN A 201
ASP A 171
ARG A 254
 None
None
None
GOL  A1415 (-4.0A)
 1.01A 2v57C-2x0fA:
undetectable		 2v57C-2x0fA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfx MHC CLASS 1

(Bos taurus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 HIS A   9
SER A  67
ASN A  70
ILE A  66
 None
 0.98A 2v57C-2xfxA:
undetectable		 2v57C-2xfxA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0f PUTATIVE
PHOSPHOGLUCOMUTASE

(Thermus
thermophilus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ASN A 115
ILE A 111
ASP A 123
ARG A  56
 None
 1.07A 2v57C-2z0fA:
undetectable		 2v57C-2z0fA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoo PROBABLE NITRITE
REDUCTASE

(Pseudoalteromonas
haloplanktis) 		PF00034
(Cytochrom_C)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3) 		4 SER A 101
ASN A  85
ILE A  86
ASP A  87
 None
None
None
CU  A 501 ( 4.1A)
 1.03A 2v57C-2zooA:
undetectable		 2v57C-2zooA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvb PRECORRIN-3
C17-METHYLTRANSFERAS
E

(Thermus
thermophilus) 		PF00590
(TP_methylase) 		4 SER A 153
ILE A 164
ASP A 156
ARG A 187
 None
 1.11A 2v57C-2zvbA:
undetectable		 2v57C-2zvbA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3act CELLOBIOSE
PHOSPHORYLASE

(Cellulomonas
gilvus) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 SER A 518
ILE A 521
ASP A 422
ARG A 367
 None
None
None
K  A2903 (-4.0A)
 0.72A 2v57C-3actA:
undetectable		 2v57C-3actA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1b CARBONIC ANHYDRASE 1

(Chlamydomonas
reinhardtii) 		PF00194
(Carb_anhydrase) 		4 HIS A 271
SER A 200
ILE A 140
ARG A 154
 None
 0.83A 2v57C-3b1bA:
undetectable		 2v57C-3b1bA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b86 GENERAL
ODORANT-BINDING
PROTEIN LUSH

(Drosophila
melanogaster) 		PF01395
(PBP_GOBP) 		4 SER A 114
TYR A 107
ASP A  35
ARG A  30
 None
 0.95A 2v57C-3b86A:
undetectable		 2v57C-3b86A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsi N,N-DIMETHYLGLYCINE
OXIDASE

(Arthrobacter
globiformis) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		4 SER A 407
ASN A 410
ASP A 340
ARG A 392
 None
 0.95A 2v57C-3gsiA:
undetectable		 2v57C-3gsiA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ

(Carboxydothermus
hydrogenoformans) 		PF14450
(FtsA) 		4 HIS A 256
ASN A   8
ASP A  12
ARG A  16
 None
 1.09A 2v57C-3h1qA:
undetectable		 2v57C-3h1qA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hf1 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B

(Homo sapiens) 		PF00268
(Ribonuc_red_sm) 		4 SER A 220
ASN A 221
ILE A 224
TYR A 145
 None
 1.08A 2v57C-3hf1A:
undetectable		 2v57C-3hf1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hsr HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SARZ

(Staphylococcus
aureus) 		PF01047
(MarR) 		4 ASN A 133
ILE A 130
ASP A 129
ARG A 125
 None
 1.11A 2v57C-3hsrA:
1.7		 2v57C-3hsrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivr PUTATIVE
LONG-CHAIN-FATTY-ACI
D COA LIGASE

(Rhodopseudomonas
palustris) 		PF00501
(AMP-binding) 		4 HIS A 378
ILE A 351
ASP A 382
ARG A 397
 None
 1.06A 2v57C-3ivrA:
undetectable		 2v57C-3ivrA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT

(Hahella
chejuensis) 		PF13407
(Peripla_BP_4) 		4 SER A  49
ASN A  50
ASP A 207
ARG A 174
 None
BDR  A   1 ( 4.3A)
None
None
 1.12A 2v57C-3ksmA:
undetectable		 2v57C-3ksmA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc2 INHIBITOR OF
CARBONIC ANHYDRASE

(Mus musculus) 		PF00405
(Transferrin) 		4 SER A 262
ILE A 263
ASP A  58
ARG A   7
 None
 0.95A 2v57C-3mc2A:
undetectable		 2v57C-3mc2A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc6 SPHINGOSINE-1-PHOSPH
ATE LYASE

(Saccharomyces
cerevisiae) 		PF00282
(Pyridoxal_deC) 		4 SER C 343
ILE C 374
ASP C 365
ARG C 367
 None
 1.02A 2v57C-3mc6C:
undetectable		 2v57C-3mc6C:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc6 SPHINGOSINE-1-PHOSPH
ATE LYASE

(Saccharomyces
cerevisiae) 		PF00282
(Pyridoxal_deC) 		4 SER C 343
ILE C 374
TYR C 476
ASP C 365
 None
 1.01A 2v57C-3mc6C:
undetectable		 2v57C-3mc6C:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE

(Parabacteroides
distasonis) 		PF03009
(GDPD) 		4 SER A 176
ILE A 156
ASP A 154
ARG A 119
 None
 1.02A 2v57C-3no3A:
undetectable		 2v57C-3no3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozy PUTATIVE MANDELATE
RACEMASE

(Bordetella
bronchiseptica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 HIS A 317
ILE A 112
ASP A 116
ARG A 120
 None
 1.02A 2v57C-3ozyA:
undetectable		 2v57C-3ozyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prl NADP-DEPENDENT
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Bacillus
halodurans) 		PF00171
(Aldedh) 		4 SER A 469
ILE A 466
ASP A 449
ARG A 112
 None
None
None
SO4  A 506 (-3.1A)
 0.90A 2v57C-3prlA:
undetectable		 2v57C-3prlA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qde CELLOBIOSE
PHOSPHORYLASE

(Ruminiclostridium
thermocellum) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 SER A 511
ILE A 514
ASP A 415
ARG A 360
 None
None
None
144  A 813 ( 4.8A)
 0.79A 2v57C-3qdeA:
undetectable		 2v57C-3qdeA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF05214
(Baculo_p33) 		4 HIS A 225
TYR A 252
ASP A 111
ARG A  10
 FAD  A 334 (-3.5A)
FAD  A 334 (-4.2A)
None
FAD  A 334 (-2.9A)
 0.89A 2v57C-3qzyA:
undetectable		 2v57C-3qzyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ram HMRA PROTEIN

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 HIS A  26
SER A  22
ASN A  96
ILE A  97
 None
 0.99A 2v57C-3ramA:
undetectable		 2v57C-3ramA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N

(Escherichia
coli) 		no annotation 4 HIS N 305
SER N 304
ILE N 281
TYR N 425
 None
 1.06A 2v57C-3rkoN:
0.5		 2v57C-3rkoN:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rwl CYTOCHROME P450
ALKANE HYDROXYLASE 1
CYP153A7

(Sphingopyxis
macrogoltabida) 		PF00067
(p450) 		4 SER A  20
ASN A 402
ILE A  84
ASP A  85
 None
 1.02A 2v57C-3rwlA:
undetectable		 2v57C-3rwlA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5k FALCILYSIN

(Plasmodium
falciparum) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 SER A 501
ASN A 499
ILE A 781
ASP A 778
 None
 0.97A 2v57C-3s5kA:
undetectable		 2v57C-3s5kA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sub ADP-RIBOSYLATION
FACTOR
GTPASE-ACTIVATING
PROTEIN

(Plasmodium
falciparum) 		PF01412
(ArfGap) 		4 HIS A  37
SER A  34
ASN A  36
ILE A  58
 None
 1.09A 2v57C-3subA:
undetectable		 2v57C-3subA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2c FRUCTOSE-1,6-BISPHOS
PHATE
ALDOLASE/PHOSPHATASE

(Pyrobaculum
neutrophilum) 		PF01950
(FBPase_3) 		4 HIS A 310
ILE A  43
ASP A  44
ARG A 286
 None
 0.95A 2v57C-3t2cA:
undetectable		 2v57C-3t2cA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT

(Methanocaldococcus
jannaschii) 		PF00694
(Aconitase_C) 		4 SER A  82
ILE A  81
ASP A  55
ARG A   8
 None
 1.00A 2v57C-3vbaA:
undetectable		 2v57C-3vbaA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbm COPPER-CONTAINING
NITRITE REDUCTASE

(Ralstonia
pickettii) 		PF07732
(Cu-oxidase_3)
PF13442
(Cytochrome_CBB3) 		4 SER A 111
ASN A  95
ILE A  96
ASP A  97
 None
None
None
CU  A1461 ( 4.1A)
 1.00A 2v57C-3zbmA:
undetectable		 2v57C-3zbmA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aee ALPHA AMYLASE,
CATALYTIC REGION

(Staphylothermus
marinus) 		PF00128
(Alpha-amylase) 		4 ASN A 167
ILE A 139
ARG A 477
TRP A  63
 None
 1.05A 2v57C-4aeeA:
undetectable		 2v57C-4aeeA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4am6 ACTIN-LIKE PROTEIN
ARP8

(Saccharomyces
cerevisiae) 		PF00022
(Actin) 		4 SER A 736
ILE A 533
ASP A 532
ARG A 621
 None
 1.00A 2v57C-4am6A:
undetectable		 2v57C-4am6A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az7 BETA-N-ACETYLHEXOSAM
INIDASE

(Streptococcus
pneumoniae) 		PF00728
(Glyco_hydro_20) 		4 SER A 191
ILE A 192
ASP A 193
ARG A 196
 None
None
None
LOG  A1614 (-2.8A)
 1.11A 2v57C-4az7A:
undetectable		 2v57C-4az7A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bl3 PENICILLIN BINDING
PROTEIN 2 PRIME

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF05223
(MecA_N) 		4 SER A 335
ASN A 339
ASP A 654
ARG A 589
 None
 1.09A 2v57C-4bl3A:
undetectable		 2v57C-4bl3A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4drs PYRUVATE KINASE

(Cryptosporidium
parvum) 		PF00224
(PK)
PF02887
(PK_C) 		4 SER A 282
ASN A 279
ILE A 283
ASP A 243
 None
 1.12A 2v57C-4drsA:
undetectable		 2v57C-4drsA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1o HISTIDINE
DECARBOXYLASE

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 HIS A 380
ILE A 460
ASP A 459
ARG A  26
 None
 1.10A 2v57C-4e1oA:
undetectable		 2v57C-4e1oA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eei ADENYLOSUCCINATE
LYASE

(Francisella
tularensis) 		PF00206
(Lyase_1) 		4 ASN A  18
ILE A  13
ASP A 108
ARG A 107
 None
 0.74A 2v57C-4eeiA:
1.0		 2v57C-4eeiA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gx8 DNA POLYMERASE III
SUBUNIT EPSILON,DNA
POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF02811
(PHP) 		4 ASN A 116
TYR A 279
ASP A 114
ARG A  55
 None
 1.10A 2v57C-4gx8A:
undetectable		 2v57C-4gx8A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ict CYTOCHROME P450 121

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 SER A 248
ILE A 247
ASP A  16
ARG A  14
 None
 1.10A 2v57C-4ictA:
undetectable		 2v57C-4ictA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana) 		PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 HIS A 696
SER A 695
ASN A 720
TYR A 648
 None
 1.10A 2v57C-4j0mA:
undetectable		 2v57C-4j0mA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l63 ECXA

(Escherichia
coli) 		PF16313
(DUF4953) 		4 ASN A  60
ILE A  77
ASP A  81
ARG A  84
 None
 1.03A 2v57C-4l63A:
1.4		 2v57C-4l63A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o7p MALTOKINASE

(Mycobacterium
tuberculosis) 		no annotation 4 SER A 408
ILE A 410
ASP A 411
ARG A 413
 None
 1.06A 2v57C-4o7pA:
undetectable		 2v57C-4o7pA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ohj TOXIC SHOCK SYNDROME
TOXIN-1

(Staphylococcus
aureus) 		PF02876
(Stap_Strp_tox_C) 		4 ILE A 166
ASP A 170
ARG A 174
TRP A 194
 None
 0.95A 2v57C-4ohjA:
undetectable		 2v57C-4ohjA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pwv P450 MONOOXYGENASE

(Streptomyces
sp. Acta 2897) 		PF00067
(p450) 		4 SER A 159
ILE A 158
ASP A 249
ARG A 253
 None
 1.09A 2v57C-4pwvA:
undetectable		 2v57C-4pwvA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsl PYRUVATE CARBOXYLASE

(Listeria
monocytogenes) 		no annotation 4 ILE H 870
TYR H 692
ASP H 869
ARG H 684
 None
 1.10A 2v57C-4qslH:
undetectable		 2v57C-4qslH:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2b EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Ochrobactrum
anthropi) 		PF01547
(SBP_bac_1) 		4 SER A 147
ASN A 149
ILE A 300
ASP A 364
 None
 1.05A 2v57C-4r2bA:
2.1		 2v57C-4r2bA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rd8 UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 4 HIS A 199
ASN A  43
ILE A 207
ASP A 205
 None
 1.03A 2v57C-4rd8A:
undetectable		 2v57C-4rd8A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rdy PARATHION HYDROLASE

(Vulcanisaeta
moutnovskia) 		PF02126
(PTE) 		4 SER A 172
ILE A 141
ASP A 181
ARG A 184
 None
None
GOL  A 405 (-4.0A)
GOL  A 407 ( 4.3A)
 0.94A 2v57C-4rdyA:
undetectable		 2v57C-4rdyA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoz BETA-GALACTOSIDASE

(Bifidobacterium
animalis) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		4 ILE A  43
TYR A 389
ASP A  42
ARG A 365
 None
 0.99A 2v57C-4uozA:
0.5		 2v57C-4uozA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgj UNCHARACTERIZED
PROTEIN

(Pectobacterium
atrosepticum) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		4 SER A 227
ILE A  91
ASP A  92
ARG A  96
 None
 1.11A 2v57C-4xgjA:
undetectable		 2v57C-4xgjA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysl BETA-LACTAMASE
DOMAIN PROTEIN

(Pseudomonas
putida) 		PF00753
(Lactamase_B) 		4 ASN A 234
ILE A 235
ASP A 176
ARG A 219
 None
 1.11A 2v57C-4yslA:
undetectable		 2v57C-4yslA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysl BETA-LACTAMASE
DOMAIN PROTEIN

(Pseudomonas
putida) 		PF00753
(Lactamase_B) 		4 SER A 233
ASN A 234
ASP A 176
ARG A 219
 None
 0.93A 2v57C-4yslA:
undetectable		 2v57C-4yslA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv1 ANCQR

(synthetic
construct) 		PF00497
(SBP_bac_3) 		4 SER A 108
ASN A 106
ILE A 109
ASP A 162
 None
 1.09A 2v57C-4zv1A:
undetectable		 2v57C-4zv1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aca VP1
VP2
VP3

(Foot-and-mouth
disease virus;
Foot-and-mouth
disease virus;
Foot-and-mouth
disease virus) 		PF00073
(Rhv)
PF00073
(Rhv)
PF00073
(Rhv) 		4 HIS 1 123
SER 3 167
ASN 2 166
TYR 3 171
 None
 1.06A 2v57C-5aca1:
undetectable		 2v57C-5aca1:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2k TRANSFORMING PROTEIN
RHOA,RAC
GTPASE-ACTIVATING
PROTEIN 1

(Homo sapiens) 		PF00071
(Ras)
PF00620
(RhoGAP) 		4 SER A 218
ILE A 224
ASP A 333
ARG A 332
 None
 1.11A 2v57C-5c2kA:
undetectable		 2v57C-5c2kA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2f BETA-LACTAMASE YBXI

(Bacillus
subtilis) 		PF00905
(Transpeptidase) 		4 ILE A 196
TYR A 128
ASP A  94
ARG A  93
 None
 0.86A 2v57C-5e2fA:
undetectable		 2v57C-5e2fA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej3 ENDO-1,4-BETA-XYLANA
SE B

(Streptomyces
lividans) 		PF00457
(Glyco_hydro_11) 		4 HIS A 154
SER A 138
ASP A  92
ARG A 144
 None
 1.09A 2v57C-5ej3A:
undetectable		 2v57C-5ej3A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ew5 COLICIN-E9

(Escherichia
coli) 		PF03515
(Cloacin) 		4 SER A 198
ASN A 196
ILE A 197
ASP A 188
 None
 1.09A 2v57C-5ew5A:
undetectable		 2v57C-5ew5A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbu PHOSPHOENOLPYRUVATE
SYNTHASE

(Listeria
monocytogenes) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N) 		4 SER A 811
ILE A 812
ASP A 794
ARG A 778
 None
 1.12A 2v57C-5fbuA:
2.6		 2v57C-5fbuA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 ASN A  71
TYR A 234
ASP A  69
ARG A  10
 None
 1.10A 2v57C-5fkuA:
undetectable		 2v57C-5fkuA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd DNA DAMAGE-BINDING
PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 SER A1096
ILE A1094
ASP A1090
ARG A1074
 None
 1.05A 2v57C-5fqdA:
undetectable		 2v57C-5fqdA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans) 		PF03067
(LPMO_10) 		4 SER A 197
TYR A 110
ASP A  34
ARG A 113
 None
 0.91A 2v57C-5ftzA:
undetectable		 2v57C-5ftzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g26 INTIMIN

(Escherichia
coli) 		PF11924
(IAT_beta) 		4 HIS A 314
SER A 311
ASP A 281
ARG A 254
 None
 0.94A 2v57C-5g26A:
undetectable		 2v57C-5g26A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2v IMPORTIN SUBUNIT
BETA-3

(Saccharomyces
cerevisiae) 		PF13513
(HEAT_EZ) 		4 ASN A 305
ILE A 265
TYR A 371
ASP A 269
 None
 1.05A 2v57C-5h2vA:
1.9		 2v57C-5h2vA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hiw CYTOCHROME P450
CYP260B1

(Sorangium
cellulosum) 		PF00067
(p450) 		4 SER A 137
ILE A 147
ASP A 151
ARG A 155
 None
 1.06A 2v57C-5hiwA:
undetectable		 2v57C-5hiwA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k47 POLYCYSTIN-2

(Homo sapiens) 		PF08016
(PKD_channel) 		4 SER A 530
ASN A 525
ILE A 526
TYR A 465
 None
 0.86A 2v57C-5k47A:
undetectable		 2v57C-5k47A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kk5 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1

(Acidaminococcus
sp. BV3L6) 		no annotation 4 HIS A1269
ASN A1265
ILE A1237
ASP A1074
 None
 0.83A 2v57C-5kk5A:
undetectable		 2v57C-5kk5A:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ly8 TAIL COMPONENT

(Lactobacillus
phage J-1) 		no annotation 4 ILE A 186
TYR A 230
ASP A 184
ARG A 182
 None
 1.07A 2v57C-5ly8A:
undetectable		 2v57C-5ly8A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE

(Jeotgalicoccus
sp. ATCC 8456) 		PF00067
(p450) 		4 ILE A 170
TYR A  21
ASP A 171
ARG A 174
 EPA  A 502 (-4.3A)
None
None
None
 0.90A 2v57C-5m0oA:
undetectable		 2v57C-5m0oA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfi MINOR FIMBRIUM
ANCHORING SUBUNIT
MFA2

(Porphyromonas
gingivalis) 		no annotation 5 HIS B 248
SER B 204
ASN B 250
TYR B 209
ARG B 284
 None
 1.49A 2v57C-5nfiB:
undetectable		 2v57C-5nfiB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nmw FLAVIN-CONTAINING
MONOOXYGENASE

(Zonocerus
variegatus) 		no annotation 4 ILE A 309
TYR A  95
ASP A 312
ARG A  18
 None
 1.06A 2v57C-5nmwA:
undetectable		 2v57C-5nmwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqw 026

(Lama glama) 		no annotation 4 HIS C  60
SER C  51
ILE C  52
ASP C  53
 None
 0.79A 2v57C-5nqwC:
undetectable		 2v57C-5nqwC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o33 KALIRIN

(Rattus
norvegicus) 		PF00621
(RhoGEF) 		4 SER B1334
ASN B1335
ILE B1338
TYR B1327
 None
 0.95A 2v57C-5o33B:
undetectable		 2v57C-5o33B:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t6u CATHEPSIN K

(Mus musculus) 		PF00112
(Peptidase_C1) 		4 HIS A 177
ILE A   5
ASP A   6
ARG A   8
 None
 1.06A 2v57C-5t6uA:
undetectable		 2v57C-5t6uA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xto FAD-LINKED
SULFHYDRYL OXIDASE

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF05214
(Baculo_p33) 		4 HIS A 225
TYR A 252
ASP A 111
ARG A  10
 FAD  A 301 (-3.3A)
FAD  A 301 ( 4.4A)
None
FAD  A 301 (-3.5A)
 0.92A 2v57C-5xtoA:
undetectable		 2v57C-5xtoA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbi PEPTIDE ASPARAGINYL
LIGASE

(Viola
canadensis) 		no annotation 4 HIS A 166
ASN A  61
TYR A 168
ARG A 375
 None
 0.94A 2v57C-5zbiA:
undetectable		 2v57C-5zbiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au1 PUTATIVE HEMIN
STORAGE PROTEIN

(Bordetella
bronchiseptica) 		no annotation 4 SER A 670
TYR A 645
ASP A 664
ARG A 631
 None
 1.09A 2v57C-6au1A:
undetectable		 2v57C-6au1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhu MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Bos taurus) 		no annotation 4 SER A1267
ASN A1054
ASP A1050
ARG A1046
 None
 0.96A 2v57C-6bhuA:
1.0		 2v57C-6bhuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1

(Saccharomyces
cerevisiae) 		no annotation 4 SER A1422
ILE A1423
ASP A 895
ARG A1380
 None
 0.86A 2v57C-6f42A:
undetectable		 2v57C-6f42A:
undetectable