SIMILAR PATTERNS OF AMINO ACIDS FOR 2V0M_C_KLNC1499

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ag9 FLAVODOXIN

(Escherichia
coli) 		PF00258
(Flavodoxin_1) 		4 LEU A  50
PHE A  78
ILE A 105
GLY A   5
 None
 0.91A 2v0mC-1ag9A:
undetectable		 2v0mC-1ag9A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)

(Homo sapiens) 		PF00168
(C2)
PF01735
(PLA2_B) 		4 PHE A 205
LEU A 560
ILE A 354
GLY A 226
 None
 1.02A 2v0mC-1cjyA:
0.0		 2v0mC-1cjyA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 PHE A 200
PHE A 395
ILE A 444
GLY A 293
 None
None
HEM  A 601 (-4.3A)
None
 1.02A 2v0mC-1ebvA:
0.0		 2v0mC-1ebvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h74 HOMOSERINE KINASE

(Methanocaldococcus
jannaschii) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 PHE A 150
SER A  15
PHE A 221
ILE A 266
 None
 0.92A 2v0mC-1h74A:
0.0		 2v0mC-1h74A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htr GASTRICSIN

(Homo sapiens) 		PF00026
(Asp) 		4 SER B  42
LEU B  80
PHE B  71
GLY B 109
 None
 0.92A 2v0mC-1htrB:
0.0		 2v0mC-1htrB:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3n 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
SYNTHASE II

(Thermus
thermophilus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 LEU A 340
PHE A 227
ILE A 197
GLY A 105
 None
 0.96A 2v0mC-1j3nA:
undetectable		 2v0mC-1j3nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jkm BREFELDIN A ESTERASE

(Bacillus
subtilis) 		PF07859
(Abhydrolase_3) 		4 PHE A  71
PHE A 259
ILE A  78
GLY A 126
 None
 0.98A 2v0mC-1jkmA:
0.0		 2v0mC-1jkmA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgu ACTIN INTERACTING
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 SER A 314
LEU A 262
ILE A 276
GLY A 308
 None
 1.00A 2v0mC-1pguA:
0.0		 2v0mC-1pguA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzx HYPOTHETICAL PROTEIN
APC36103

(Geobacillus
stearothermophilus) 		PF02645
(DegV) 		4 LEU A 169
PHE A 161
ILE A 200
GLY A 172
 None
PLM  A 702 ( 4.2A)
None
None
 0.85A 2v0mC-1pzxA:
undetectable		 2v0mC-1pzxA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q87 39 KDA INITIATOR
BINDING PROTEIN

(Trichomonas
vaginalis) 		PF11422
(IBP39) 		4 PHE A 231
LEU A 255
PHE A 276
ILE A 295
 None
 0.95A 2v0mC-1q87A:
undetectable		 2v0mC-1q87A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1snz ALDOSE 1-EPIMERASE

(Homo sapiens) 		PF01263
(Aldose_epim) 		4 SER A 177
PHE A 339
ILE A  40
GLY A 183
 None
 0.96A 2v0mC-1snzA:
undetectable		 2v0mC-1snzA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmh TRIOSEPHOSPHATE
ISOMERASE

(Escherichia
coli) 		PF00121
(TIM) 		4 LEU A 127
PHE A 161
ILE A 192
GLY A  96
 None
 1.01A 2v0mC-1tmhA:
undetectable		 2v0mC-1tmhA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txg GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Archaeoglobus
fulgidus) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 PHE A 174
PHE A 154
ILE A 168
GLY A  12
 None
 0.86A 2v0mC-1txgA:
undetectable		 2v0mC-1txgA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ud9 DNA POLYMERASE
SLIDING CLAMP A

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A  51
PHE A  27
ILE A  87
GLY A 234
 None
 0.89A 2v0mC-1ud9A:
undetectable		 2v0mC-1ud9A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ajr SUGAR KINASE, PFKB
FAMILY

(Thermotoga
maritima) 		PF00294
(PfkB) 		4 SER A  46
LEU A  70
PHE A  85
ILE A  81
 None
 0.74A 2v0mC-2ajrA:
undetectable		 2v0mC-2ajrA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asu HEPATOCYTE GROWTH
FACTOR-LIKE PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 PHE B 506
PHE B 524
ILE B 517
GLY B 533
 None
 0.91A 2v0mC-2asuB:
undetectable		 2v0mC-2asuB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2i AMMONIUM TRANSPORTER

(Archaeoglobus
fulgidus) 		PF00909
(Ammonium_transp) 		4 SER A 160
PHE A 204
ILE A 103
GLY A 312
 None
 0.74A 2v0mC-2b2iA:
undetectable		 2v0mC-2b2iA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b71 CYCLOPHILIN-LIKE
PROTEIN

(Plasmodium
yoelii) 		PF00160
(Pro_isomerase) 		4 LEU A 125
PHE A  66
ILE A 186
GLY A 123
 None
 0.94A 2v0mC-2b71A:
undetectable		 2v0mC-2b71A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw7 ENDONUCLEASE
PI-PKOII

(Thermococcus
kodakarensis) 		PF14528
(LAGLIDADG_3)
PF14890
(Intein_splicing) 		4 LEU A 281
PHE A 326
ILE A 272
GLY A 283
 None
 0.84A 2v0mC-2cw7A:
undetectable		 2v0mC-2cw7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5u N-GLYCANASE 1

(Mus musculus) 		PF09409
(PUB) 		4 SER A  37
LEU A 103
ILE A 110
GLY A  84
 None
 0.84A 2v0mC-2d5uA:
undetectable		 2v0mC-2d5uA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dep THERMOSTABLE
CELLOXYLANASE

([Clostridium]
stercorarium) 		PF00331
(Glyco_hydro_10) 		4 LEU A  81
PHE A 110
ILE A  70
GLY A  58
 None
 0.88A 2v0mC-2depA:
undetectable		 2v0mC-2depA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpl GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG] SUBUNIT B

(Pyrococcus
horikoshii) 		PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		4 PHE A  52
SER A  34
ILE A 182
GLY A 190
 None
 0.68A 2v0mC-2dplA:
undetectable		 2v0mC-2dplA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f51 THIOREDOXIN

(Trichomonas
vaginalis) 		PF00085
(Thioredoxin) 		4 LEU A  80
PHE A  82
ILE A  48
GLY A  98
 None
 1.02A 2v0mC-2f51A:
undetectable		 2v0mC-2f51A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f96 RIBONUCLEASE T

(Pseudomonas
aeruginosa) 		PF00929
(RNase_T) 		4 PHE A  26
LEU A  64
PHE A 206
GLY A  62
 None
 0.98A 2v0mC-2f96A:
undetectable		 2v0mC-2f96A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmu PUTATIVE
PYRIDOXAMINE
5-PHOSPHATE-DEPENDEN
T DEHYDRASE, WBDK

(Escherichia
coli) 		PF01041
(DegT_DnrJ_EryC1) 		4 LEU A 263
PHE A  45
ILE A 270
GLY A 259
 None
 0.92A 2v0mC-2gmuA:
undetectable		 2v0mC-2gmuA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6t CANDIDAPEPSIN-3

(Candida
albicans) 		PF00026
(Asp) 		4 PHE A 279
PHE A 264
ILE A 208
GLY A 260
 None
 0.88A 2v0mC-2h6tA:
undetectable		 2v0mC-2h6tA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzk TRAP-T FAMILY
SORBITOL/MANNITOL
TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN, SMOM

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		4 PHE A 181
PHE A 327
ILE A 334
GLY A  98
 None
 0.91A 2v0mC-2hzkA:
undetectable		 2v0mC-2hzkA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzk TRAP-T FAMILY
SORBITOL/MANNITOL
TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN, SMOM

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		4 PHE A 181
SER A 117
ILE A 334
GLY A  98
 None
 0.91A 2v0mC-2hzkA:
undetectable		 2v0mC-2hzkA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m83 PROTEIN PHOSPHATASE
1 REGULATORY SUBUNIT
3A

(Oryctolagus
cuniculus) 		PF03370
(CBM_21) 		4 PHE A 112
SER A 222
ILE A 211
GLY A  99
 None
 0.92A 2v0mC-2m83A:
undetectable		 2v0mC-2m83A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nul PEPTIDYLPROLYL
ISOMERASE

(Escherichia
coli) 		PF00160
(Pro_isomerase) 		4 LEU A  83
PHE A  27
ILE A 157
GLY A  81
 None
 0.91A 2v0mC-2nulA:
undetectable		 2v0mC-2nulA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nxf PUTATIVE DIMETAL
PHOSPHATASE

(Danio rerio) 		PF00149
(Metallophos) 		4 PHE A  99
PHE A 201
PHE A 261
GLY A  95
 None
 0.98A 2v0mC-2nxfA:
undetectable		 2v0mC-2nxfA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Deinococcus
geothermalis) 		PF02627
(CMD) 		4 PHE A 172
SER A 179
PHE A  62
GLY A  98
 None
 0.87A 2v0mC-2oyoA:
undetectable		 2v0mC-2oyoA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzw CANDIDAPEPSIN-1

(Candida
albicans) 		PF00026
(Asp) 		4 PHE A 279
PHE A 264
ILE A 208
GLY A 260
 None
 1.02A 2v0mC-2qzwA:
undetectable		 2v0mC-2qzwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjt BETA-KETOACYL-ACP
SYNTHASE II

(Streptococcus
pneumoniae) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 LEU A 339
PHE A 229
ILE A 200
GLY A 108
 None
 0.88A 2v0mC-2rjtA:
undetectable		 2v0mC-2rjtA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpn PERIPLASMIC
SUBSTRATE BINDING
PROTEIN

(Halomonas
elongata) 		PF03480
(DctP) 		4 PHE A 104
SER A  97
PHE A  77
GLY A 296
 None
 0.92A 2v0mC-2vpnA:
undetectable		 2v0mC-2vpnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wns OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Homo sapiens) 		PF00156
(Pribosyltran) 		4 PHE A  23
SER A  34
LEU A 180
GLY A 195
 None
 0.92A 2v0mC-2wnsA:
undetectable		 2v0mC-2wnsA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wrz L-ARABINOSE-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00532
(Peripla_BP_1) 		4 PHE A 248
LEU A 121
ILE A 169
GLY A 228
 None
 0.99A 2v0mC-2wrzA:
undetectable		 2v0mC-2wrzA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN

(Bordetella
bronchiseptica) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 SER A 474
PHE A 344
ILE A 470
GLY A 450
 None
None
None
ATP  A1607 ( 4.5A)
 0.79A 2v0mC-2x0qA:
undetectable		 2v0mC-2x0qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xkr PUTATIVE CYTOCHROME
P450 142

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 PHE A 321
LEU A 239
ILE A 114
GLY A 242
 None
 0.88A 2v0mC-2xkrA:
30.1		 2v0mC-2xkrA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ypj ENDOGLUCANASE CEL5A

([Eubacterium]
cellulosolvens) 		no annotation 4 PHE A 628
LEU A 641
PHE A 643
ILE A 613
 None
 0.91A 2v0mC-2ypjA:
undetectable		 2v0mC-2ypjA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zf5 GLYCEROL KINASE

(Thermococcus
kodakarensis) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 SER O 182
LEU O 266
ILE O 283
GLY O 297
 None
 0.89A 2v0mC-2zf5O:
undetectable		 2v0mC-2zf5O:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahy BETA-GLUCOSIDASE

(Trichoderma
reesei) 		PF00232
(Glyco_hydro_1) 		4 PHE A 139
PHE A 118
ILE A  30
GLY A  86
 None
 0.88A 2v0mC-3ahyA:
undetectable		 2v0mC-3ahyA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3au7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Archaeoglobus
fulgidus) 		PF01336
(tRNA_anti-codon)
PF08489
(DUF1743) 		4 LEU A 333
PHE A 287
ILE A 338
GLY A 324
 None
 1.02A 2v0mC-3au7A:
undetectable		 2v0mC-3au7A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE

(Leishmania
naiffi) 		PF03167
(UDG) 		4 PHE A 190
LEU A 268
PHE A 287
GLY A 216
 None
 0.91A 2v0mC-3cxmA:
undetectable		 2v0mC-3cxmA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmq METHIONINE
AMINOPEPTIDASE 2

(Encephalitozoon
cuniculi) 		PF00557
(Peptidase_M24) 		4 SER A  42
LEU A 352
PHE A 239
GLY A  26
 None
 0.90A 2v0mC-3fmqA:
undetectable		 2v0mC-3fmqA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g04 THYROTROPIN RECEPTOR

(Homo sapiens) 		PF13306
(LRR_5) 		4 PHE C 141
LEU C 156
PHE C 172
GLY C 132
 None
 0.95A 2v0mC-3g04C:
undetectable		 2v0mC-3g04C:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 SER A 186
LEU A 271
ILE A 289
GLY A 303
 None
 0.90A 2v0mC-3g25A:
undetectable		 2v0mC-3g25A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g64 PUTATIVE ENOYL-COA
HYDRATASE

(Streptomyces
coelicolor) 		PF00378
(ECH_1) 		4 PHE A  72
PHE A  96
ILE A  82
GLY A 126
 None
 1.00A 2v0mC-3g64A:
undetectable		 2v0mC-3g64A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h51 PUTATIVE
CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE II
ASSOCIATION DOMAIN

(Xanthomonas
campestris) 		PF08332
(CaMKII_AD) 		4 LEU A  51
PHE A  88
ILE A 150
GLY A  98
 None
 0.64A 2v0mC-3h51A:
undetectable		 2v0mC-3h51A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvy CYSTATHIONINE
BETA-LYASE FAMILY
PROTEIN, YNBB
B.SUBTILIS ORTHOLOG

(Clostridium
acetobutylicum) 		PF06838
(Met_gamma_lyase) 		4 LEU A 404
PHE A 347
ILE A 313
GLY A 406
 None
 0.84A 2v0mC-3hvyA:
undetectable		 2v0mC-3hvyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i16 ALUMINUM RESISTANCE
PROTEIN

(Clostridium
novyi) 		PF06838
(Met_gamma_lyase) 		4 LEU A 404
PHE A 347
ILE A 313
GLY A 406
 None
 0.79A 2v0mC-3i16A:
undetectable		 2v0mC-3i16A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Leptospira
interrogans) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		4 SER A  49
PHE A  88
ILE A  45
GLY A 119
 None
None
None
S2N  A 260 ( 3.8A)
 1.02A 2v0mC-3i3aA:
undetectable		 2v0mC-3i3aA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8u HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		4 PHE A 368
SER A 403
PHE A 300
ILE A 372
 None
 1.01A 2v0mC-3m8uA:
undetectable		 2v0mC-3m8uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nur AMIDOHYDROLASE

(Staphylococcus
aureus) 		PF04909
(Amidohydro_2) 		4 SER A 238
LEU A 191
ILE A 240
GLY A 229
 None
 1.02A 2v0mC-3nurA:
undetectable		 2v0mC-3nurA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8j 2-METHYLCITRATE
SYNTHASE

(Salmonella
enterica) 		PF00285
(Citrate_synt) 		4 SER A 331
LEU A 194
ILE A 287
GLY A 170
 None
 0.69A 2v0mC-3o8jA:
undetectable		 2v0mC-3o8jA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p02 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14274
(DUF4361)
PF16343
(DUF4973) 		4 SER A 264
LEU A 187
ILE A 253
GLY A 189
 None
 0.96A 2v0mC-3p02A:
undetectable		 2v0mC-3p02A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT J
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT K

(Escherichia
coli) 		no annotation 4 LEU J  46
PHE J   5
ILE J  39
GLY K  50
 None
 0.90A 2v0mC-3rkoJ:
undetectable		 2v0mC-3rkoJ:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkx BIOTIN-[ACETYL-COA-C
ARBOXYLASE] LIGASE

(Staphylococcus
aureus) 		PF03099
(BPL_LplA_LipB)
PF08279
(HTH_11) 		4 PHE A 244
SER A 169
ILE A 183
GLY A 160
 None
 0.91A 2v0mC-3rkxA:
undetectable		 2v0mC-3rkxA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 PHE A 239
LEU A 281
PHE A 297
GLY A 253
 None
 1.01A 2v0mC-3t6qA:
undetectable		 2v0mC-3t6qA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgh GLIDEOSOME-ASSOCIATE
D PROTEIN 50

(Plasmodium
falciparum) 		PF00149
(Metallophos) 		4 PHE A  60
SER A  31
LEU A 304
ILE A 253
 None
 0.87A 2v0mC-3tghA:
undetectable		 2v0mC-3tghA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE

(Bifidobacterium
longum) 		PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C) 		4 PHE A  96
PHE A 153
ILE A  90
GLY A 265
 None
 1.02A 2v0mC-3wfzA:
undetectable		 2v0mC-3wfzA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ypi TRIOSEPHOSPHATE
ISOMERASE

(Saccharomyces
cerevisiae) 		PF00121
(TIM) 		4 PHE A   6
SER A  50
ILE A  20
GLY A   8
 None
 0.64A 2v0mC-3ypiA:
undetectable		 2v0mC-3ypiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 PHE B1724
SER B1801
LEU B1676
ILE B1668
 None
 0.85A 2v0mC-3zefB:
undetectable		 2v0mC-3zefB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zth STU0660

(Streptococcus
thermophilus) 		PF16813
(Cas_St_Csn2) 		4 SER A 251
LEU A 321
PHE A 289
ILE A 246
 None
 0.93A 2v0mC-3zthA:
undetectable		 2v0mC-3zthA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apw ALP12

(Clostridium
tetani) 		no annotation 4 PHE A 169
SER A 281
ILE A 305
GLY A 158
 None
 1.00A 2v0mC-4apwA:
undetectable		 2v0mC-4apwA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmb GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  19
PHE A 114
ILE A 130
GLY A 139
 None
 1.00A 2v0mC-4bmbA:
undetectable		 2v0mC-4bmbA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btm TAU-TUBULIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 223
PHE A 184
ILE A 169
GLY A 225
 None
 1.00A 2v0mC-4btmA:
undetectable		 2v0mC-4btmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0q HYALURONATE LYASE

(Streptococcus
pneumoniae) 		PF02018
(CBM_4_9) 		4 SER A 159
PHE A 199
ILE A 171
GLY A 140
 None
 0.75A 2v0mC-4d0qA:
undetectable		 2v0mC-4d0qA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1g FIBER PROTEIN

(Snake
atadenovirus A) 		no annotation 4 PHE A 285
PHE A 258
ILE A 307
GLY A 278
 None
 0.88A 2v0mC-4d1gA:
undetectable		 2v0mC-4d1gA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 PHE A 298
PHE A 387
LEU A 377
ILE A 139
 None
 1.02A 2v0mC-4dxyA:
28.7		 2v0mC-4dxyA:
26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1j GLYCEROL KINASE

(Sinorhizobium
meliloti) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 SER A 209
LEU A 293
ILE A 311
GLY A 325
 None
 0.92A 2v0mC-4e1jA:
undetectable		 2v0mC-4e1jA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e54 DNA DAMAGE-BINDING
PROTEIN 2

(Homo sapiens) 		PF00400
(WD40) 		4 PHE B 110
PHE B 186
LEU B 162
GLY B 130
 None
 1.02A 2v0mC-4e54B:
undetectable		 2v0mC-4e54B:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsf PENICILLIN-BINDING
PROTEIN 3

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 PHE A 507
SER A 302
ILE A 449
GLY A 509
 None
 0.59A 2v0mC-4fsfA:
undetectable		 2v0mC-4fsfA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gn2 OXACILLINASE

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase) 		4 PHE A  65
SER A 161
PHE A 129
GLY A 137
 None
 0.75A 2v0mC-4gn2A:
undetectable		 2v0mC-4gn2A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN ALPHA-X

(Homo sapiens) 		PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 PHE A 748
LEU A 698
PHE A 673
ILE A 635
 None
 0.84A 2v0mC-4nenA:
undetectable		 2v0mC-4nenA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsx U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN 21

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 SER A 265
PHE A  39
ILE A 310
GLY A 297
 None
 0.98A 2v0mC-4nsxA:
undetectable		 2v0mC-4nsxA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pbo C-REACTIVE PROTEIN

(Danio rerio) 		PF00354
(Pentaxin) 		4 PHE A  52
LEU A  28
ILE A 193
GLY A 132
 None
 0.90A 2v0mC-4pboA:
undetectable		 2v0mC-4pboA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4umi FIBER PROTEIN

(Snake
atadenovirus A) 		no annotation 4 PHE A 285
PHE A 258
ILE A 307
GLY A 278
 None
 0.90A 2v0mC-4umiA:
undetectable		 2v0mC-4umiA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xnu INTEGRAL MEMBRANE
PROTEIN-DOPAMINE
TRANSPORTER

(Drosophila
melanogaster) 		PF00209
(SNF) 		4 PHE A 470
PHE A 118
SER A 426
GLY A 459
 None
 0.99A 2v0mC-4xnuA:
undetectable		 2v0mC-4xnuA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zke SUPERKILLER PROTEIN
7

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU) 		4 PHE A 364
LEU A 382
ILE A 442
GLY A 274
 PHE  A 364 ( 1.3A)
LEU  A 382 ( 0.6A)
ILE  A 442 ( 0.7A)
GLY  A 274 ( 0.0A)
 1.01A 2v0mC-4zkeA:
undetectable		 2v0mC-4zkeA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a11 THIOCYANATE FORMING
PROTEIN

(Thlaspi arvense) 		PF01344
(Kelch_1) 		4 PHE A 251
SER A 312
PHE A 199
GLY A 185
 None
None
None
IOD  A1349 ( 3.8A)
 0.97A 2v0mC-5a11A:
undetectable		 2v0mC-5a11A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c78 ATP-DRIVEN FLIPPASE
PGLK

(Campylobacter
jejuni) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 LEU A 555
PHE A 365
ILE A 395
GLY A 382
 None
 0.93A 2v0mC-5c78A:
undetectable		 2v0mC-5c78A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eco GLUTATHIONE
S-TRANSFERASE U20

(Arabidopsis
thaliana) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 PHE B 106
LEU B 182
PHE B 164
ILE B 158
 None
 0.99A 2v0mC-5ecoB:
undetectable		 2v0mC-5ecoB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evi BETA-LACTAMASE/D-ALA
NINE
CARBOXYPEPTIDASE

(Pseudomonas
syringae group
genomosp. 3) 		PF00144
(Beta-lactamase) 		4 PHE B 134
PHE B 116
ILE B 103
GLY B 158
 None
 0.89A 2v0mC-5eviB:
undetectable		 2v0mC-5eviB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f2o FATTY ACID
O-METHYLTRANSFERASE

(Mycobacterium
marinum) 		PF03492
(Methyltransf_7) 		4 SER A 125
LEU A  72
ILE A  79
GLY A  68
 None
 0.97A 2v0mC-5f2oA:
undetectable		 2v0mC-5f2oA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		4 PHE A 568
LEU A 521
PHE A 526
ILE A 493
 None
 0.96A 2v0mC-5hdhA:
undetectable		 2v0mC-5hdhA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i92 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Pseudomonas
aeruginosa) 		PF00202
(Aminotran_3) 		4 PHE A 181
LEU A 220
ILE A 201
GLY A 218
 None
 1.00A 2v0mC-5i92A:
undetectable		 2v0mC-5i92A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE

(Pseudomonas
aeruginosa) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 SER A 700
LEU A 723
ILE A 766
GLY A 721
 None
 1.00A 2v0mC-5im3A:
undetectable		 2v0mC-5im3A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iwd DNA POLYMERASE
PROCESSIVITY FACTOR

(Human
betaherpesvirus
5) 		PF03325
(Herpes_PAP) 		4 PHE A  90
LEU A  48
PHE A 102
ILE A  24
 None
 0.95A 2v0mC-5iwdA:
undetectable		 2v0mC-5iwdA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iww MULTIPLE ORGANELLAR
RNA EDITING FACTOR
9, CHLOROPLASTIC
PLS9-PPR

(Arabidopsis
thaliana;
unidentified) 		PF12854
(PPR_1)
PF13041
(PPR_2)
no annotation 		4 SER D 182
LEU A  82
PHE D 141
GLY A  84
 None
 1.01A 2v0mC-5iwwD:
undetectable		 2v0mC-5iwwD:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5p DNA TOPOISOMERASE 4
SUBUNIT B

(Streptococcus
pneumoniae) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		4 PHE A 339
LEU A  57
ILE A  64
GLY A 117
 None
 0.95A 2v0mC-5j5pA:
undetectable		 2v0mC-5j5pA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jja SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 PHE A 163
PHE A 140
SER A 147
PHE A  42
 PHE  A 163 ( 1.3A)
PHE  A 140 ( 1.3A)
SER  A 147 ( 0.0A)
PHE  A  42 ( 1.3A)
 0.93A 2v0mC-5jjaA:
undetectable		 2v0mC-5jjaA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oet GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 30
(GPA-GSS30-APO)

(Globodera
pallida) 		no annotation 4 PHE B 478
SER B  94
ILE B 454
GLY B 476
 None
 0.83A 2v0mC-5oetB:
undetectable		 2v0mC-5oetB:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szj MICAL
C-TERMINAL-LIKE
PROTEIN
RAS-RELATED PROTEIN
RAB-10

(Homo sapiens) 		PF00071
(Ras)
PF12130
(DUF3585) 		4 PHE A  38
PHE A  71
PHE B 650
ILE B 657
 GNP  A 301 (-4.0A)
None
None
None
 1.02A 2v0mC-5szjA:
undetectable		 2v0mC-5szjA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tsb MEMBRANE PROTEIN

(Bordetella
bronchiseptica) 		PF02535
(Zip) 		4 SER A 236
LEU A 224
ILE A 174
GLY A 227
 None
 0.96A 2v0mC-5tsbA:
undetectable		 2v0mC-5tsbA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris) 		no annotation 4 LEU A 211
PHE A 209
ILE A 230
GLY A 214
 None
 0.84A 2v0mC-5u6fA:
undetectable		 2v0mC-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue0 CT622 PROTEIN

(Chlamydia
trachomatis) 		no annotation 4 LEU A 482
PHE A 646
ILE A 541
GLY A 485
 None
 0.87A 2v0mC-5ue0A:
undetectable		 2v0mC-5ue0A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2

(Saccharomyces
cerevisiae) 		no annotation 4 PHE A 209
LEU A 259
PHE A 190
ILE A 233
 None
 0.97A 2v0mC-5vncA:
undetectable		 2v0mC-5vncA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgw ISOASPARTYL
DIPEPTIDASE

(Colwellia
psychrerythraea) 		no annotation 4 PHE A  67
LEU A  63
PHE A  58
ILE A   9
 None
 1.02A 2v0mC-5xgwA:
undetectable		 2v0mC-5xgwA:
9.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xxi CYTOCHROME P450 2C9

(Homo sapiens) 		no annotation 4 LEU A 131
PHE A 263
ILE A 123
GLY A 437
 None
None
None
HEM  A 504 (-3.5A)
 1.02A 2v0mC-5xxiA:
36.7		 2v0mC-5xxiA:
30.02