SIMILAR PATTERNS OF AMINO ACIDS FOR 2UZ2_A_ACTA1123
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bw0 | PROTEIN (TYROSINEAMINOTRANSFERASE) (Trypanosomacruzi) |
PF00155(Aminotran_1_2) | 4 | ASN A 48LEU A 49THR A 44VAL A 256 | NoneNoneNoneLLP A 253 ( 4.1A) | 1.17A | 2uz2A-1bw0A:undetectable | 2uz2A-1bw0A:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezi | CMP-N-ACETYLNEURAMINIC ACID SYNTHETASE (Neisseriameningitidis) |
PF02348(CTP_transf_3) | 4 | ASN A 181SER A 129THR A 197VAL A 131 | None | 1.18A | 2uz2A-1eziA:undetectable | 2uz2A-1eziA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hsk | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Staphylococcusaureus) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | LEU A 99SER A 97TYR A 52THR A 54 | None | 0.96A | 2uz2A-1hskA:undetectable | 2uz2A-1hskA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i5p | PESTICIDIAL CRYSTALPROTEIN CRY2AA (Bacillusthuringiensis) |
PF03944(Endotoxin_C)PF03945(Endotoxin_N)PF09131(Endotoxin_mid) | 4 | ASN A 336LEU A 316SER A 334THR A 332 | None | 1.02A | 2uz2A-1i5pA:undetectable | 2uz2A-1i5pA:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmz | AMINE DEHYDROGENASE (Pseudomonasputida) |
no annotation | 4 | LEU B 261TYR B 199THR B 259VAL B 300 | None | 1.03A | 2uz2A-1jmzB:undetectable | 2uz2A-1jmzB:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p9w | GENERAL SECRETIONPATHWAY PROTEIN E (Vibrio cholerae) |
PF00437(T2SSE) | 4 | LEU A 493SER A 492THR A 491VAL A 486 | None | 1.15A | 2uz2A-1p9wA:undetectable | 2uz2A-1p9wA:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pby | QUINOHEMOPROTEINAMINE DEHYDROGENASE40 KDA SUBUNIT (Paracoccusdenitrificans) |
no annotation | 4 | LEU B 221TYR B 203THR B 219VAL B 236 | None | 1.12A | 2uz2A-1pbyB:undetectable | 2uz2A-1pbyB:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1swf | CIRCULARLY PERMUTEDCORE-STREPTAVIDINE51/A46 (Streptomycesavidinii) |
PF01382(Avidin) | 5 | ASN A 23LEU A 25SER A 27TYR A 43TRP A 92 | None | 0.38A | 2uz2A-1swfA:undetectable | 2uz2A-1swfA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vky | S-ADENOSYLMETHIONINE:TRNARIBOSYLTRANSFERASE-ISOMERASE (Thermotogamaritima) |
PF02547(Queuosine_synth) | 4 | ASN A 59LEU A 199SER A 61VAL A 201 | None | 1.12A | 2uz2A-1vkyA:undetectable | 2uz2A-1vkyA:15.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wbi | AVIDIN-RELATEDPROTEIN 2 (Gallus gallus) |
PF01382(Avidin) | 6 | ASN A 12LEU A 14SER A 16TYR A 33THR A 35VAL A 37 | BTN A1001 (-3.3A)BTN A1001 ( 4.8A)BTN A1001 (-2.7A)BTN A1001 (-4.6A)BTN A1001 (-3.8A)BTN A1001 (-4.9A) | 0.36A | 2uz2A-1wbiA:20.4 | 2uz2A-1wbiA:48.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wbi | AVIDIN-RELATEDPROTEIN 2 (Gallus gallus) |
PF01382(Avidin) | 5 | ASN A 116LEU A 14TYR A 33THR A 35VAL A 37 | BTN A1001 (-3.4A)BTN A1001 ( 4.8A)BTN A1001 (-4.6A)BTN A1001 (-3.8A)BTN A1001 (-4.9A) | 1.05A | 2uz2A-1wbiA:20.4 | 2uz2A-1wbiA:48.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdi | HYPOTHETICAL PROTEINTT0907 (Thermusthermophilus) |
PF02547(Queuosine_synth) | 4 | ASN A 61LEU A 209SER A 63VAL A 211 | CIT A1322 (-4.4A)NoneNoneNone | 1.14A | 2uz2A-1wdiA:undetectable | 2uz2A-1wdiA:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wpx | CARBOXYPEPTIDASE YINHIBITOR (Saccharomycescerevisiae) |
PF01161(PBP) | 4 | LEU B 666SER B 711TYR B 515VAL B 664 | None | 1.19A | 2uz2A-1wpxB:undetectable | 2uz2A-1wpxB:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x90 | INVERTASE/PECTINMETHYLESTERASEINHIBITOR FAMILYPROTEIN (Arabidopsisthaliana) |
PF04043(PMEI) | 4 | ASN A 144LEU A 140SER A 143VAL A 101 | None | 1.16A | 2uz2A-1x90A:undetectable | 2uz2A-1x90A:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yt8 | THIOSULFATESULFURTRANSFERASE (Pseudomonasaeruginosa) |
PF00581(Rhodanese) | 4 | LEU A 299SER A 302TYR A 294VAL A 328 | None | 1.08A | 2uz2A-1yt8A:undetectable | 2uz2A-1yt8A:12.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2a8g | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 5 | ASN A 12LEU A 14SER A 16TYR A 33THR A 35 | None | 0.64A | 2uz2A-2a8gA:19.4 | 2uz2A-2a8gA:54.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c1q | BIOTIN BINDINGPROTEIN A (Gallus gallus) |
PF01382(Avidin) | 6 | ASN A 12LEU A 14SER A 16TYR A 33THR A 35VAL A 37 | BTN A1126 (-3.3A)BTN A1126 (-4.8A)BTN A1126 (-2.6A)BTN A1126 (-4.5A)BTN A1126 (-3.6A)None | 0.29A | 2uz2A-2c1qA:20.1 | 2uz2A-2c1qA:49.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c1q | BIOTIN BINDINGPROTEIN A (Gallus gallus) |
PF01382(Avidin) | 5 | ASN A 119LEU A 14TYR A 33THR A 35VAL A 37 | BTN A1126 (-3.2A)BTN A1126 (-4.8A)BTN A1126 (-4.5A)BTN A1126 (-3.6A)None | 1.17A | 2uz2A-2c1qA:20.1 | 2uz2A-2c1qA:49.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c4i | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 5 | ASN A 63LEU A 93TYR A 112THR A 114VAL A 116 | BTN A1274 (-3.2A)BTN A1274 ( 4.9A)BTN A1274 (-4.5A)BTN A1274 (-3.7A)BTN A1274 (-4.9A) | 1.10A | 2uz2A-2c4iA:4.7 | 2uz2A-2c4iA:31.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c4i | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 6 | ASN A 91LEU A 93SER A 95TYR A 112THR A 114VAL A 116 | BTN A1274 (-3.3A)BTN A1274 ( 4.9A)BTN A1274 (-2.7A)BTN A1274 (-4.5A)BTN A1274 (-3.7A)BTN A1274 (-4.9A) | 0.36A | 2uz2A-2c4iA:4.7 | 2uz2A-2c4iA:31.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c4i | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 5 | ASN A 184LEU A 214TYR A 233THR A 235VAL A 237 | BTN A1275 (-3.2A)BTN A1275 (-4.8A)BTN A1275 (-4.6A)BTN A1275 (-3.7A)BTN A1275 (-4.8A) | 1.10A | 2uz2A-2c4iA:4.7 | 2uz2A-2c4iA:31.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c4i | AVIDIN (Gallus gallus) |
PF01382(Avidin) | 6 | ASN A 212LEU A 214SER A 216TYR A 233THR A 235VAL A 237 | BTN A1275 (-3.2A)BTN A1275 (-4.8A)BTN A1275 (-2.6A)BTN A1275 (-4.6A)BTN A1275 (-3.7A)BTN A1275 (-4.8A) | 0.36A | 2uz2A-2c4iA:4.7 | 2uz2A-2c4iA:31.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cyg | BETA-1, 3-GLUCANANSE (Musa acuminata) |
PF00332(Glyco_hydro_17) | 4 | ASN A 324SER A 269THR A 278VAL A 335 | None | 1.14A | 2uz2A-2cygA:undetectable | 2uz2A-2cygA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czq | CUTINASE-LIKEPROTEIN (Cryptococcussp. S-2) |
PF01083(Cutinase) | 4 | ASN A 126LEU A 123THR A 157VAL A 154 | None | 1.03A | 2uz2A-2czqA:undetectable | 2uz2A-2czqA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d52 | PENTAKETIDE CHROMONESYNTHASE (Aloearborescens) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | LEU A 399THR A 397VAL A 299TRP A 316 | None | 0.97A | 2uz2A-2d52A:undetectable | 2uz2A-2d52A:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fb5 | HYPOTHETICALMEMBRANE SPANNINGPROTEIN (Bacillus cereus) |
PF02457(DisA_N)PF10372(YojJ) | 4 | ASN A 150LEU A 139SER A 147THR A 113 | None | 1.16A | 2uz2A-2fb5A:undetectable | 2uz2A-2fb5A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fb5 | HYPOTHETICALMEMBRANE SPANNINGPROTEIN (Bacillus cereus) |
PF02457(DisA_N)PF10372(YojJ) | 4 | ASN A 150LEU A 139THR A 113VAL A 146 | None | 1.04A | 2uz2A-2fb5A:undetectable | 2uz2A-2fb5A:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fhl | AVIDIN-RELATEDPROTEIN 4/5 (Gallus gallus) |
PF01382(Avidin) | 6 | ASN A 12LEU A 14SER A 16TYR A 33THR A 35VAL A 37 | BNI A 501 (-3.4A)BNI A 501 ( 4.9A)BNI A 501 (-2.7A)BNI A 501 (-4.6A)BNI A 501 (-3.6A)BNI A 501 (-4.9A) | 0.38A | 2uz2A-2fhlA:20.9 | 2uz2A-2fhlA:56.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fhl | AVIDIN-RELATEDPROTEIN 4/5 (Gallus gallus) |
PF01382(Avidin) | 5 | ASN A 116LEU A 14TYR A 33THR A 35VAL A 37 | BNI A 501 (-3.3A)BNI A 501 ( 4.9A)BNI A 501 (-4.6A)BNI A 501 (-3.6A)BNI A 501 (-4.9A) | 1.13A | 2uz2A-2fhlA:20.9 | 2uz2A-2fhlA:56.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h84 | STEELY1 (Dictyosteliumdiscoideum) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | LEU A2962SER A2961TYR A2842VAL A2839 | None | 1.08A | 2uz2A-2h84A:undetectable | 2uz2A-2h84A:14.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hqm | GLUTATHIONEREDUCTASE (Saccharomycescerevisiae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 51TYR A 26THR A 49VAL A 132 | None | 1.10A | 2uz2A-2hqmA:undetectable | 2uz2A-2hqmA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv2 | FORMATEDEHYDROGENASE H (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | LEU X 227SER X 311TYR X 255THR X 559 | None | 1.17A | 2uz2A-2iv2X:undetectable | 2uz2A-2iv2X:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iwb | METHICILLINRESISTANCE MECR1PROTEIN (Staphylococcusaureus) |
PF00905(Transpeptidase) | 4 | ASN A 491TYR A 342THR A 344VAL A 346 | None | 1.12A | 2uz2A-2iwbA:undetectable | 2uz2A-2iwbA:20.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2jgs | CIRCULAR PERMUTANTOF AVIDIN (Gallus gallus) |
PF01382(Avidin) | 6 | ASN A 104LEU A 106SER A 108TYR A 125THR A 127VAL A 129 | BTN A1001 ( 4.4A)NoneBTN A1001 (-2.6A)BTN A1001 (-4.5A)BTN A1001 (-3.7A)None | 0.37A | 2uz2A-2jgsA:undetectable | 2uz2A-2jgsA:35.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lnv | GENERAL SECRETIONPATHWAY PROTEIN C (Dickeyadadantii) |
PF11356(T2SSC) | 4 | ASN A 94LEU A 95TYR A 147VAL A 128 | None | 1.11A | 2uz2A-2lnvA:undetectable | 2uz2A-2lnvA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nyf | NOSTOC PUNCTIFORMEPHENYLALANINEAMMONIA LYASE (Nostocpunctiforme) |
PF00221(Lyase_aromatic) | 4 | ASN A 152LEU A 151THR A 46VAL A 41 | None | 1.17A | 2uz2A-2nyfA:undetectable | 2uz2A-2nyfA:12.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o4c | ERYTHRONATE-4-PHOSPHATE DEHYDROGENASE (Pseudomonasaeruginosa) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C)PF11890(DUF3410) | 4 | ASN A 205LEU A 173SER A 207THR A 175 | NoneNoneNAD A1002 (-4.7A)NAD A1002 (-4.3A) | 1.17A | 2uz2A-2o4cA:undetectable | 2uz2A-2o4cA:15.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjr | PROTEIN (HELICASEPCRA)PROTEIN (HELICASEPCRA) (Geobacillusstearothermophilus;Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C)PF13361(UvrD_C) | 4 | ASN A 297LEU A 293TYR B 605THR B 609 | None | 1.10A | 2uz2A-2pjrA:undetectable | 2uz2A-2pjrA:13.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qvl | DIACYLGLYCEROLKINASE DGKB (Staphylococcusaureus) |
PF00781(DAGK_cat) | 4 | LEU A 178SER A 262THR A 264VAL A 176 | None | 1.07A | 2uz2A-2qvlA:undetectable | 2uz2A-2qvlA:19.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2uz2 | XENAVIDIN (Xenopustropicalis) |
PF01382(Avidin) | 7 | ASN A 14LEU A 16SER A 18TYR A 35THR A 37VAL A 39TRP A 78 | ACT A1123 (-3.4A)ACT A1123 ( 4.7A)ACT A1123 (-2.5A)ACT A1123 (-4.5A)ACT A1123 (-3.8A)ACT A1123 (-4.9A)None | 0.00A | 2uz2A-2uz2A:24.8 | 2uz2A-2uz2A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x05 | EXO-BETA-D-GLUCOSAMINIDASE (Amycolatopsisorientalis) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 4 | ASN A 854LEU A 868THR A 820VAL A 821 | None | 1.18A | 2uz2A-2x05A:undetectable | 2uz2A-2x05A:9.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2y32 | BLR5658 PROTEIN (Bradyrhizobiumjaponicum) |
PF01382(Avidin) | 4 | ASN A 9SER A 13TYR A 31TRP A 75 | None | 0.54A | 2uz2A-2y32A:13.3 | 2uz2A-2y32A:32.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsc | TAMAVIDIN2 (Pleurotuscornucopiae) |
PF01382(Avidin) | 6 | ASN A 14LEU A 16SER A 18TYR A 34VAL A 38TRP A 80 | BTN A 301 (-3.4A)BTN A 301 ( 4.9A)BTN A 301 (-2.6A)BTN A 301 (-4.5A)BTN A 301 (-4.8A)BTN A 301 (-4.8A) | 0.29A | 2uz2A-2zscA:15.8 | 2uz2A-2zscA:29.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3du1 | ALL3740 PROTEIN (Nostoc sp. PCC7120) |
PF00805(Pentapeptide) | 4 | ASN X 116LEU X 141SER X 118THR X 143 | None | 1.05A | 2uz2A-3du1X:undetectable | 2uz2A-3du1X:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ew2 | RHIZAVIDIN (Rhizobium etli) |
PF01382(Avidin) | 4 | ASN A 21SER A 25TYR A 41TRP A 85 | BTN A 400 (-3.6A)BTN A 400 (-2.6A)BTN A 400 (-4.4A)BTN A 400 ( 4.7A) | 0.22A | 2uz2A-3ew2A:14.7 | 2uz2A-3ew2A:28.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7m | SENSOR PROTEIN (Geobactersulfurreducens) |
PF00497(SBP_bac_3) | 4 | ASN A 82TYR A 238THR A 139VAL A 276 | None | 1.16A | 2uz2A-3h7mA:undetectable | 2uz2A-3h7mA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbx | GLUTAMATEDECARBOXYLASE 1 (Arabidopsisthaliana) |
PF00282(Pyridoxal_deC) | 4 | ASN A 232LEU A 228VAL A 196TRP A 237 | None | 1.17A | 2uz2A-3hbxA:undetectable | 2uz2A-3hbxA:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdy | UDP-GALACTOPYRANOSEMUTASE (Deinococcusradiodurans) |
PF03275(GLF)PF13450(NAD_binding_8) | 4 | LEU A 191SER A 159THR A 196VAL A 195 | NoneNoneGDU A 500 (-4.6A)GDU A 500 (-4.9A) | 1.17A | 2uz2A-3hdyA:undetectable | 2uz2A-3hdyA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i7a | PUTATIVEMETAL-DEPENDENTPHOSPHOHYDROLASE (Shewanellaamazonensis) |
PF08668(HDOD) | 4 | SER A 121THR A 120VAL A 117TRP A 212 | None | 0.97A | 2uz2A-3i7aA:undetectable | 2uz2A-3i7aA:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ip3 | OXIDOREDUCTASE,PUTATIVE (Thermotogamaritima) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | LEU A 78SER A 77THR A 172VAL A 75 | None | 1.10A | 2uz2A-3ip3A:undetectable | 2uz2A-3ip3A:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6e | OXIDOREDUCTASE,SHORT-CHAINDEHYDROGENASE/REDUCTASE FAMILY (Aeromonashydrophila) |
PF00106(adh_short) | 4 | LEU A 58SER A 111THR A 112VAL A 115 | None | 1.18A | 2uz2A-3l6eA:undetectable | 2uz2A-3l6eA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mue | PANTOTHENATESYNTHETASE (Salmonellaenterica) |
PF02569(Pantoate_ligase) | 4 | ASN A 139SER A 135TYR A 168VAL A 109 | None | 1.13A | 2uz2A-3mueA:undetectable | 2uz2A-3mueA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nh9 | ATP-BINDING CASSETTESUB-FAMILY B MEMBER6, MITOCHONDRIAL (Homo sapiens) |
PF00005(ABC_tran) | 4 | LEU A 583SER A 661THR A 658VAL A 657 | None | 1.13A | 2uz2A-3nh9A:undetectable | 2uz2A-3nh9A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwn | KINESIN-LIKE PROTEINKIF9 (Homo sapiens) |
PF00225(Kinesin) | 4 | LEU A 142SER A 140TYR A 223THR A 221 | UNX A1005 ( 4.4A)UNX A1005 ( 2.9A)NoneUNX A1005 ( 3.9A) | 0.95A | 2uz2A-3nwnA:undetectable | 2uz2A-3nwnA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oa0 | LIPOPOLYSACCHARIDEBIOSYNTHESIS PROTEINWBPB (Thermusthermophilus) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | SER A 246TYR A 244THR A 155VAL A 153 | None | 1.05A | 2uz2A-3oa0A:undetectable | 2uz2A-3oa0A:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oep | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA0988 (Thermusthermophilus) |
PF02626(CT_A_B)PF02682(CT_C_D) | 4 | LEU A 133TYR A 112THR A 157VAL A 152 | None | 0.99A | 2uz2A-3oepA:undetectable | 2uz2A-3oepA:11.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pzu | ENDOGLUCANASE (Bacillussubtilis) |
PF00150(Cellulase) | 4 | LEU A 271SER A 274THR A 260VAL A 269 | None | 1.09A | 2uz2A-3pzuA:undetectable | 2uz2A-3pzuA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q10 | PANTOATE--BETA-ALANINE LIGASE (Yersinia pestis) |
PF02569(Pantoate_ligase) | 4 | ASN A 139SER A 135TYR A 168VAL A 109 | None | 1.04A | 2uz2A-3q10A:undetectable | 2uz2A-3q10A:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfk | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 4 | LEU A 77SER A 74TYR A 102THR A 106 | None | 1.01A | 2uz2A-3qfkA:undetectable | 2uz2A-3qfkA:13.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3re5 | STREPTAVIDIN (Streptomycesavidinii) |
PF01382(Avidin) | 6 | ASN A 23LEU A 25SER A 27TYR A 43VAL A 47TRP A 92 | None | 0.61A | 2uz2A-3re5A:15.7 | 2uz2A-3re5A:33.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t2x | AVIDIN/STREPTAVIDIN (Shewanelladenitrificans) |
PF01382(Avidin) | 4 | ASN A 15SER A 19TYR A 36TRP A 80 | None | 0.38A | 2uz2A-3t2xA:15.7 | 2uz2A-3t2xA:28.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdp | FORMATE/NITRITETRANSPORTER (Clostridioidesdifficile) |
PF01226(Form_Nir_trans) | 4 | ASN A 115LEU A 82THR A 80VAL A 75 | None | 1.10A | 2uz2A-3tdpA:undetectable | 2uz2A-3tdpA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zqj | UVRABC SYSTEMPROTEIN A (Mycobacteriumtuberculosis) |
PF00005(ABC_tran) | 4 | ASN A 677LEU A 698THR A 865VAL A 866 | None | 1.02A | 2uz2A-3zqjA:undetectable | 2uz2A-3zqjA:8.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0t | PUP--PROTEIN LIGASE (Corynebacteriumglutamicum) |
PF03136(Pup_ligase) | 4 | ASN A 57SER A 59TYR A 71THR A 73 | NoneNoneNoneADP A1478 (-3.9A) | 0.85A | 2uz2A-4b0tA:undetectable | 2uz2A-4b0tA:14.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4bbo | BLR5658 PROTEIN (Bradyrhizobiumjaponicum) |
PF01382(Avidin) | 4 | ASN A 9SER A 13TYR A 31TRP A 75 | BTN A1001 (-3.3A)BTN A1001 (-2.6A)BTN A1001 (-4.9A)BTN A1001 (-4.9A) | 0.23A | 2uz2A-4bboA:14.6 | 2uz2A-4bboA:36.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4bj8 | ZEBAVIDIN (Danio rerio) |
PF01382(Avidin) | 7 | ASN A 14LEU A 16SER A 18TYR A 33THR A 35VAL A 37TRP A 78 | BTN A1123 (-3.7A)BTN A1123 ( 4.8A)BTN A1123 (-2.8A)BTN A1123 (-4.5A)BTN A1123 (-3.8A)NoneBTN A1123 (-4.9A) | 0.35A | 2uz2A-4bj8A:18.5 | 2uz2A-4bj8A:32.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c30 | DNA HELICASE II (Deinococcusradiodurans) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | ASN A 301LEU A 297TYR A 612THR A 616 | None | 1.17A | 2uz2A-4c30A:undetectable | 2uz2A-4c30A:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4p | PROTEIN ATS1,DIPHTHAMIDEBIOSYNTHESIS PROTEIN3 (Saccharomycescerevisiae) |
PF00415(RCC1)PF05207(zf-CSL) | 4 | ASN A 240LEU A 259THR A 277TRP A 235 | None | 1.10A | 2uz2A-4d4pA:undetectable | 2uz2A-4d4pA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dag | FUSION GLYCOPROTEINF0 (Humanmetapneumovirus) |
PF00523(Fusion_gly) | 4 | LEU A 39SER A 37THR A 281VAL A 278 | None | 1.13A | 2uz2A-4dagA:undetectable | 2uz2A-4dagA:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dne | STREPTAVIDIN (Streptomycesavidinii) |
PF01382(Avidin) | 6 | ASN A 23LEU A 25SER A 27TYR A 43THR A 45TRP A 92 | DTB A 201 (-3.4A)DTB A 201 ( 4.7A)DTB A 201 (-2.6A)DTB A 201 (-4.7A)DTB A 201 (-3.7A)DTB A 201 ( 4.5A) | 0.35A | 2uz2A-4dneA:16.6 | 2uz2A-4dneA:28.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fer | EXPANSIN-YOAJ (Bacillussubtilis) |
PF03330(DPBB_1) | 4 | ASN A 86SER A 84TYR A 18VAL A 67 | None | 1.17A | 2uz2A-4ferA:undetectable | 2uz2A-4ferA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h0a | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF00188(CAP)PF14504(CAP_assoc_N) | 4 | LEU A 189SER A 190TYR A 116THR A 118 | None | 1.04A | 2uz2A-4h0aA:undetectable | 2uz2A-4h0aA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ix8 | TYROSINEAMINOTRANSFERASE (Leishmaniainfantum) |
PF00155(Aminotran_1_2) | 4 | ASN A 86LEU A 87THR A 82VAL A 289 | NoneNoneNoneLLP A 286 ( 3.7A) | 1.17A | 2uz2A-4ix8A:undetectable | 2uz2A-4ix8A:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j3o | OUTER MEMBRANE USHERPROTEIN FIMD (Escherichiacoli) |
PF00577(Usher)PF13953(PapC_C)PF13954(PapC_N) | 4 | LEU D 417SER D 393TYR D 366VAL D 320 | None | 0.96A | 2uz2A-4j3oD:4.6 | 2uz2A-4j3oD:10.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6o | METALLOPHOSPHOESTERASE (Ruminiclostridiumthermocellum) |
PF00149(Metallophos) | 4 | LEU A 383TYR A 374THR A 388VAL A 385 | None | 1.12A | 2uz2A-4j6oA:undetectable | 2uz2A-4j6oA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jnj | STREPTAVIDIN/RHIZAVIDIN HYBRID (Streptomycesavidinii) |
PF01382(Avidin) | 4 | ASN A 23SER A 27TYR A 43TRP A 92 | BTN A 201 (-3.4A)BTN A 201 (-2.6A)BTN A 201 (-4.6A)BTN A 201 ( 4.8A) | 0.14A | 2uz2A-4jnjA:14.8 | 2uz2A-4jnjA:28.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jo6 | STREPTAVIDIN (Streptomycesavidinii) |
PF01382(Avidin) | 5 | ASN A 23LEU A 25SER A 27TYR A 43TRP A 92 | None | 0.70A | 2uz2A-4jo6A:15.6 | 2uz2A-4jo6A:32.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jo6 | STREPTAVIDINSBP-TAG (Streptomycesavidinii;) |
PF01382(Avidin)no annotation | 5 | ASN A 23LEU A 25SER A 27TYR A 43VAL Y 13 | None | 1.30A | 2uz2A-4jo6A:15.6 | 2uz2A-4jo6A:32.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kh3 | ANTIGEN 43 (Escherichiacoli) |
PF16168(AIDA) | 4 | LEU A 470SER A 473THR A 454VAL A 451 | None | 1.06A | 2uz2A-4kh3A:undetectable | 2uz2A-4kh3A:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l4q | S-ADENOSYLMETHIONINESYNTHASE (Thermococcuskodakarensis) |
PF01941(AdoMet_Synthase) | 4 | ASN A 294LEU A 296TYR A 169VAL A 26 | None | 1.10A | 2uz2A-4l4qA:undetectable | 2uz2A-4l4qA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbo | SERINE-RICH REPEATADHESIONGLYCOPROTEIN (SRR1) (Streptococcusagalactiae) |
PF10425(SdrG_C_C) | 4 | SER A 484TYR A 498THR A 500VAL A 482 | None | 1.17A | 2uz2A-4mboA:undetectable | 2uz2A-4mboA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mrp | ABC TRANSPORTERRELATED PROTEIN (Novosphingobiumaromaticivorans) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | LEU A 354SER A 432THR A 429VAL A 428 | None | 1.10A | 2uz2A-4mrpA:undetectable | 2uz2A-4mrpA:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s13 | FERULIC ACIDDECARBOXYLASE 1 (Saccharomycescerevisiae) |
PF01977(UbiD) | 4 | ASN A 463LEU A 404TYR A 470VAL A 367 | None | 1.15A | 2uz2A-4s13A:undetectable | 2uz2A-4s13A:14.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4std | SCYTALONEDEHYDRATASE (Magnaporthegrisea) |
PF02982(Scytalone_dh) | 4 | ASN A 131LEU A 106SER A 129VAL A 108 | BFS A 173 (-3.4A)BFS A 173 (-4.5A)BFS A 173 (-3.3A)BFS A 173 ( 4.4A) | 1.06A | 2uz2A-4stdA:undetectable | 2uz2A-4stdA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yv2 | SPERMIDINE SYNTHASE,PUTATIVE (Trypanosomacruzi) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | ASN A 200LEU A 245TYR A 185VAL A 227 | None | 1.11A | 2uz2A-4yv2A:undetectable | 2uz2A-4yv2A:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z2v | AVIDIN FAMILY (Hoefleaphototrophica) |
PF01382(Avidin) | 4 | ASN A 22SER A 26TYR A 48TRP A 94 | None | 0.36A | 2uz2A-4z2vA:14.4 | 2uz2A-4z2vA:27.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztu | DNA POLYMERASESUBUNIT GAMMA-2,MITOCHONDRIAL (Homo sapiens) |
PF03129(HGTP_anticodon) | 4 | LEU B 385TYR B 432THR B 440VAL B 441 | None | 1.09A | 2uz2A-4ztuB:undetectable | 2uz2A-4ztuB:13.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 4 | LEU A 120SER A 119TYR A 374VAL A 117 | None | 1.18A | 2uz2A-5aexA:undetectable | 2uz2A-5aexA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bz0 | REPLICASEPOLYPROTEIN 1AB (Aviancoronavirus) |
PF08715(Viral_protease) | 4 | ASN A 100LEU A 94TYR A 141TRP A 102 | None | 1.09A | 2uz2A-5bz0A:undetectable | 2uz2A-5bz0A:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c53 | POL GAMMA B (Homo sapiens) |
PF03129(HGTP_anticodon) | 4 | LEU B 385TYR B 432THR B 440VAL B 441 | None | 1.10A | 2uz2A-5c53B:undetectable | 2uz2A-5c53B:9.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dac | PUTATIVEUNCHARACTERIZEDPROTEIN,PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF13476(AAA_23) | 4 | LEU A 119SER A 117THR A 96VAL A 94 | None | 1.03A | 2uz2A-5dacA:undetectable | 2uz2A-5dacA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsl | 778AA LONGHYPOTHETICALBETA-GALACTOSIDASE (Pyrococcushorikoshii) |
PF02449(Glyco_hydro_42) | 4 | ASN A 169LEU A 166SER A 168VAL A 275 | None | 0.94A | 2uz2A-5gslA:undetectable | 2uz2A-5gslA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ilg | PHOTORECEPTORDEHYDROGENASE,ISOFORM C (Drosophilamelanogaster) |
PF00106(adh_short) | 4 | ASN A 89SER A 113TYR A 74VAL A 64 | NoneNoneNoneNAD A 302 (-3.6A) | 1.17A | 2uz2A-5ilgA:undetectable | 2uz2A-5ilgA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jgj | UBIE/COQ5 FAMILYMETHYLTRANSFERASE,PUTATIVE (Aspergillusfumigatus) |
PF01209(Ubie_methyltran) | 4 | LEU A 280THR A 282VAL A 213TRP A 193 | None | 1.05A | 2uz2A-5jgjA:undetectable | 2uz2A-5jgjA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lki | TCDA1 (Photorhabdusluminescens) |
PF03538(VRP1) | 4 | ASN A2374SER A2390TYR A1982THR A2483 | None | 1.18A | 2uz2A-5lkiA:undetectable | 2uz2A-5lkiA:4.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lki | TCDA1 (Photorhabdusluminescens) |
PF03538(VRP1) | 4 | LEU A1949SER A 110THR A 108VAL A 104 | None | 1.14A | 2uz2A-5lkiA:undetectable | 2uz2A-5lkiA:4.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msw | THIOESTER REDUCTASEDOMAIN-CONTAININGPROTEIN (Segniliparusrugosus) |
PF00501(AMP-binding)PF00550(PP-binding) | 4 | ASN A 710LEU A 706SER A 709VAL A 722 | None | 0.96A | 2uz2A-5mswA:undetectable | 2uz2A-5mswA:7.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x8z | PENICILLIN VACYLASE-LIKE PROTEIN (Shewanellaloihica) |
no annotation | 4 | ASN A 79LEU A 83THR A 77VAL A 85 | None | 1.17A | 2uz2A-5x8zA:undetectable | 2uz2A-5x8zA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bp2 | ENVELOPEGLYCOPROTEIN (Marburgmarburgvirus) |
no annotation | 4 | ASN A 80SER A 151TYR A 155THR A 153 | None | 0.98A | 2uz2A-6bp2A:undetectable | 2uz2A-6bp2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6exv | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB3 (Sus scrofa) |
no annotation | 4 | ASN C 55LEU C 159SER C 57VAL C 151 | None | 1.09A | 2uz2A-6exvC:undetectable | 2uz2A-6exvC:undetectable |