SIMILAR PATTERNS OF AMINO ACIDS FOR 2UVN_B_ECNB1406_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aso ASCORBATE OXIDASE

(Cucurbita pepo) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		5 PRO A 478
PRO A 477
GLY A 458
THR A 491
VAL A 483
 None
 1.30A 2uvnB-1asoA:
0.0		 2uvnB-1asoA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC

(Escherichia
coli) 		PF00358
(PTS_EIIA_1) 		5 PRO A  54
THR A 136
GLY A  92
THR A  95
LEU A 124
 None
 1.40A 2uvnB-1f3gA:
undetectable		 2uvnB-1f3gA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fy1 HEPARIN-BINDING
PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 MET A  91
MET A  76
THR A  38
GLY A  28
LEU A  95
 None
 1.14A 2uvnB-1fy1A:
0.0		 2uvnB-1fy1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g7c ELONGATION FACTOR
1-ALPHA

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		5 ASP A 330
PRO A 332
GLY A 334
LEU A 419
TYR A 416
 None
 1.30A 2uvnB-1g7cA:
0.0		 2uvnB-1g7cA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ile ISOLEUCYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		5 PRO A 292
PRO A 291
GLY A 236
THR A 342
VAL A 351
 None
 1.16A 2uvnB-1ileA:
1.0		 2uvnB-1ileA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN

(Salmonella
enterica) 		PF00654
(Voltage_CLC) 		5 PRO A 359
MET A 360
MET A 398
GLY A 149
THR A 151
 None
None
None
CL  A 503 ( 3.7A)
None
 1.47A 2uvnB-1kplA:
0.0		 2uvnB-1kplA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mov GFP-LIKE
NON-FLUORESCENT
CHROMOPROTEIN

(Montipora
efflorescens) 		PF01353
(GFP) 		5 ASP A  78
PRO A  80
PRO A 190
MET A 189
THR A  73
 None
None
None
IOD  A 303 ( 4.8A)
None
 1.40A 2uvnB-1movA:
0.0		 2uvnB-1movA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mty METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylococcus
capsulatus) 		PF02332
(Phenol_Hydrox) 		5 PRO B 327
GLY B 322
LEU B 234
TYR B 252
VAL B 251
 None
 0.81A 2uvnB-1mtyB:
0.1		 2uvnB-1mtyB:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q7s BIT1

(Homo sapiens) 		PF01981
(PTH2) 		5 PRO A 121
THR A 125
THR A 173
TYR A 179
VAL A 118
 None
 1.44A 2uvnB-1q7sA:
0.0		 2uvnB-1q7sA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhb HALOPEROXIDASE

(Corallina
officinalis) 		PF01569
(PAP2) 		5 ASP A 555
GLY A 544
LEU A 162
TYR A 552
VAL A 550
 None
 1.43A 2uvnB-1qhbA:
undetectable		 2uvnB-1qhbA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4y RIBONUCLEASE
ALPHA-SARCIN

(Aspergillus
giganteus) 		no annotation 5 ASP A  77
PRO A  66
PRO A  65
GLY A  46
TYR A  79
 None
 1.50A 2uvnB-1r4yA:
undetectable		 2uvnB-1r4yA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0n PLATELET
GLYCOPROTEIN IB

(Homo sapiens) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		5 PRO D  26
PRO D  27
THR D  33
LEU D  38
VAL D  15
 None
 1.28A 2uvnB-1u0nD:
undetectable		 2uvnB-1u0nD:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u1h 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Arabidopsis
thaliana) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		5 PRO A   9
THR A 333
GLY A 295
THR A 326
VAL A   6
 None
 1.34A 2uvnB-1u1hA:
undetectable		 2uvnB-1u1hA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwd LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE

(Thermus
thermophilus) 		PF01451
(LMWPc) 		5 ASP A  41
PRO A  19
MET A  20
GLY A  13
THR A  45
 MG  A1001 (-2.6A)
None
None
None
None
 1.47A 2uvnB-2cwdA:
undetectable		 2uvnB-2cwdA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5r CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		5 ASP A 161
MET A 236
THR A  80
GLY A 228
LEU A 209
 None
 1.29A 2uvnB-2d5rA:
undetectable		 2uvnB-2d5rA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fp3 CASPASE NC

(Drosophila
melanogaster) 		PF00656
(Peptidase_C14) 		5 PRO A 316
MET A 269
MET A 200
THR A 413
TYR A 371
 None
 1.45A 2uvnB-2fp3A:
undetectable		 2uvnB-2fp3A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fsn HYPOTHETICAL PROTEIN
TA0583

(Thermoplasma
acidophilum) 		no annotation 5 ASP A 191
THR A 278
GLY A 172
THR A 186
VAL A 195
 None
 1.44A 2uvnB-2fsnA:
undetectable		 2uvnB-2fsnA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fuv PHOSPHOGLUCOMUTASE

(Salmonella
enterica) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		5 ASP A 260
MET A 287
GLY A 238
THR A  87
VAL A 262
 None
 1.41A 2uvnB-2fuvA:
undetectable		 2uvnB-2fuvA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inr DNA TOPOISOMERASE 4
SUBUNIT A

(Staphylococcus
aureus) 		PF00521
(DNA_topoisoIV) 		5 ASP A 112
PRO A 114
MET A  86
THR A 120
GLY A 104
 None
 1.40A 2uvnB-2inrA:
undetectable		 2uvnB-2inrA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2irw CORTICOSTEROID
11-BETA-DEHYDROGENAS
E ISOZYME 1

(Homo sapiens) 		PF00106
(adh_short) 		5 GLY A 249
THR A 211
LEU A 215
TYR A 258
VAL A 256
 None
None
NAP  A 901 (-4.1A)
None
None
 1.40A 2uvnB-2irwA:
undetectable		 2uvnB-2irwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyj ALPHA-AMINODIPATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		5 ASP A 202
PRO A 170
THR A 180
GLY A 178
THR A 176
 PGU  A 500 (-2.8A)
None
None
None
None
 1.49A 2uvnB-2zyjA:
undetectable		 2uvnB-2zyjA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a6p EXPORTIN-5

(Homo sapiens) 		PF08389
(Xpo1) 		5 ASP A 163
MET A 154
THR A 230
GLY A 233
LEU A 182
 None
 1.28A 2uvnB-3a6pA:
2.4		 2uvnB-3a6pA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cer POSSIBLE
EXOPOLYPHOSPHATASE-L
IKE PROTEIN

(Bifidobacterium
longum) 		PF02541
(Ppx-GppA) 		5 MET A 238
THR A 234
THR A 158
LEU A 303
VAL A 151
 None
 1.31A 2uvnB-3cerA:
1.0		 2uvnB-3cerA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwb PEPTIDASE M16
INACTIVE DOMAIN
FAMILY PROTEIN

(Pseudomonas
protegens) 		PF05193
(Peptidase_M16_C) 		5 PRO A 305
MET A 306
THR A 304
GLY A 302
LEU A 159
 None
 1.49A 2uvnB-3gwbA:
undetectable		 2uvnB-3gwbA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihj ALANINE
AMINOTRANSFERASE 2

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		5 PRO A 378
PRO A 377
THR A 185
GLY A 351
THR A 339
 None
 1.15A 2uvnB-3ihjA:
undetectable		 2uvnB-3ihjA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora sp.
20) 		PF01353
(GFP) 		5 ASP A  74
PRO A  76
PRO A 186
MET A 185
THR A  69
 None
 1.40A 2uvnB-3ir8A:
undetectable		 2uvnB-3ir8A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
elegans) 		PF02373
(JmjC) 		5 PRO A 440
PRO A 439
MET A 361
GLY A 579
LEU A 560
 None
 1.42A 2uvnB-3n9oA:
2.4		 2uvnB-3n9oA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
elegans) 		PF02373
(JmjC) 		5 PRO A 440
PRO A 439
MET A 361
GLY A 580
LEU A 560
 None
 1.48A 2uvnB-3n9oA:
2.4		 2uvnB-3n9oA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ndp ADENYLATE KINASE
ISOENZYME 4

(Homo sapiens) 		PF00406
(ADK)
PF05191
(ADK_lid) 		5 PRO A  14
PRO A  13
GLY A  17
THR A  20
LEU A 138
 SO4  A 501 (-4.4A)
None
SO4  A 501 (-3.0A)
None
None
 1.49A 2uvnB-3ndpA:
undetectable		 2uvnB-3ndpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no4 CREATININE
AMIDOHYDROLASE

(Nostoc
punctiforme) 		PF02633
(Creatininase) 		5 PRO A 218
PRO A 170
THR A 169
GLY A 165
VAL A 193
 None
 1.22A 2uvnB-3no4A:
undetectable		 2uvnB-3no4A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r1i SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE

(Mycobacterium
marinum) 		PF13561
(adh_short_C2) 		5 ASP A  73
THR A 118
GLY A 122
THR A 126
VAL A  75
 None
 1.27A 2uvnB-3r1iA:
undetectable		 2uvnB-3r1iA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tau GUANYLATE KINASE

(Listeria
monocytogenes) 		PF00625
(Guanylate_kin) 		5 ASP A 170
PRO A 125
GLY A  17
THR A  20
VAL A 172
 None
None
SO4  A 206 (-3.3A)
None
SO4  A 207 (-3.8A)
 1.39A 2uvnB-3tauA:
undetectable		 2uvnB-3tauA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsj 2-AMINO-5-CHLOROPHEN
OL 1,6-DIOXYGENASE
BETA SUBUNIT

(Comamonas
testosteroni) 		PF02900
(LigB) 		5 PRO B 213
MET B 208
THR B 278
GLY B 283
THR B 192
 None
None
None
None
2XP  B 402 (-3.2A)
 1.45A 2uvnB-3vsjB:
undetectable		 2uvnB-3vsjB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgv MALATE DEHYDROGENASE

(Picrophilus
torridus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 PRO A 235
THR A  17
GLY A  15
THR A  83
VAL A 124
 None
 1.34A 2uvnB-4bgvA:
undetectable		 2uvnB-4bgvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT

(Mus musculus) 		no annotation 5 ASP D 234
PRO D 237
GLY D  91
LEU D  46
TYR D  49
 None
 1.38A 2uvnB-4f9lD:
undetectable		 2uvnB-4f9lD:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iov CAPSID PROTEIN VP1

(Adeno-associated
virus) 		PF00740
(Parvo_coat) 		5 ASP A 608
PRO A 521
MET A 522
LEU A 537
TYR A 610
 None
 1.42A 2uvnB-4iovA:
undetectable		 2uvnB-4iovA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7w TRANSPORTER,
SODIUM/BILE ACID
SYMPORTER FAMILY

(Yersinia
frederiksenii) 		PF01758
(SBF) 		5 PRO A 138
THR A 137
GLY A 133
THR A 130
VAL A 165
 None
 1.47A 2uvnB-4n7wA:
0.4		 2uvnB-4n7wA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ng4 PHOSPHOGLYCERATE
KINASE

(Coxiella
burnetii) 		PF00162
(PGK) 		5 ASP A 283
GLY A 295
THR A 298
LEU A 225
VAL A 263
 None
 1.22A 2uvnB-4ng4A:
undetectable		 2uvnB-4ng4A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6t GLYCOSYL HYDROLASE,
FAMILY 18

(Pseudomonas
protegens) 		PF00704
(Glyco_hydro_18) 		6 PRO A  98
THR A  64
GLY A  62
THR A  38
LEU A  96
TYR A  97
 None
 1.48A 2uvnB-4q6tA:
undetectable		 2uvnB-4q6tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkm XYLOSE ISOMERASE

(Bacteroides
thetaiotaomicron) 		no annotation 5 PRO A 314
GLY A 302
THR A 275
LEU A 320
VAL A 271
 None
 1.49A 2uvnB-4xkmA:
undetectable		 2uvnB-4xkmA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xz3 ACYL-COA SYNTHETASE
(NDP FORMING)

(Candidatus
Korarchaeum
cryptofilum) 		PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig) 		5 PRO A  44
MET A  53
GLY A  17
LEU A  33
VAL A  72
 None
None
COA  A 501 (-3.3A)
None
None
 1.49A 2uvnB-4xz3A:
undetectable		 2uvnB-4xz3A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		5 GLY A  78
THR A  76
LEU A 425
TYR A 295
VAL A 297
 None
 1.45A 2uvnB-5a5gA:
undetectable		 2uvnB-5a5gA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ci5 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Pseudothermotoga
lettingae) 		PF13416
(SBP_bac_8) 		5 PRO A 371
GLY A  85
LEU A  96
TYR A 127
VAL A 120
 None
 1.49A 2uvnB-5ci5A:
undetectable		 2uvnB-5ci5A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5izd D-GLYCERALDEHYDE
DEHYDROGENASE
(NADP(+))

(Thermoplasma
acidophilum) 		PF00171
(Aldedh) 		5 PRO A 151
THR A 177
GLY A 179
THR A   3
LEU A 171
 None
 1.25A 2uvnB-5izdA:
0.7		 2uvnB-5izdA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khn RND TRANSPORTER

(Burkholderia
multivorans) 		no annotation 5 PRO B 377
MET B 376
THR B 748
LEU B 734
VAL B 786
 None
 1.30A 2uvnB-5khnB:
1.1		 2uvnB-5khnB:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldd CCZ1

(Chaetomium
thermophilum) 		PF08217
(DUF1712) 		5 ASP B 199
PRO B 192
PRO B 193
LEU B 246
VAL B 244
 None
 1.31A 2uvnB-5lddB:
undetectable		 2uvnB-5lddB:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ow6 CAPSID PROTEIN, VP2

(Cucumber mosaic
virus) 		PF00760
(Cucumo_coat) 		5 PRO B  77
PRO B  78
GLY B  87
LEU B 201
VAL B 185
 None
 1.48A 2uvnB-5ow6B:
undetectable		 2uvnB-5ow6B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuw INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00478
(IMPDH) 		5 MET A  59
MET A  63
THR A  55
GLY A  50
VAL A 249
 None
 1.27A 2uvnB-5uuwA:
undetectable		 2uvnB-5uuwA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vlh PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9

(Homo sapiens) 		PF00082
(Peptidase_S8)
PF05922
(Inhibitor_I9) 		5 ASP A 343
PRO A 345
THR A 353
GLY A 337
VAL A 441
 None
 1.46A 2uvnB-5vlhA:
undetectable		 2uvnB-5vlhA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x41 COBALT TRANSPORT
PROTEIN CBIM

(Rhodobacter
capsulatus) 		no annotation 5 PRO M 120
THR M  73
GLY M  74
THR M 197
VAL M 141
 None
 1.34A 2uvnB-5x41M:
1.0		 2uvnB-5x41M:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5v GD

(Suid
alphaherpesvirus
1) 		PF01537
(Herpes_glycop_D) 		5 PRO A 132
MET A 133
MET A 218
THR A 131
THR A  36
 None
 1.50A 2uvnB-5x5vA:
undetectable		 2uvnB-5x5vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6acd -

(-) 		no annotation 5 PRO A 710
MET A 709
GLY A 928
LEU A 804
VAL A 808
 None
 1.38A 2uvnB-6acdA:
undetectable		 2uvnB-6acdA:
undetectable