SIMILAR PATTERNS OF AMINO ACIDS FOR 2R3A_A_SAMA304

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1peg HISTONE H3
METHYLTRANSFERASE
DIM-5

(Neurospora
crassa) 		PF00856
(SET)
PF05033
(Pre-SET) 		6 ARG A 159
GLY A 160
TRP A 161
HIS A 242
TYR A 283
CYH A 308
 None
SAH  A 319 ( 4.6A)
SAH  A 319 (-4.8A)
SAH  A 319 (-4.3A)
SAH  A 319 (-4.7A)
ZN  A   4 (-2.2A)
 1.33A 2r3aA-1pegA:
27.1		 2r3aA-1pegA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1peg HISTONE H3
METHYLTRANSFERASE
DIM-5

(Neurospora
crassa) 		PF00856
(SET)
PF05033
(Pre-SET) 		9 ARG A 159
GLY A 160
TRP A 161
TYR A 204
HIS A 242
TYR A 283
CYH A 306
CYH A 308
LEU A 317
 None
SAH  A 319 ( 4.6A)
SAH  A 319 (-4.8A)
SAH  A 319 (-4.0A)
SAH  A 319 (-4.3A)
SAH  A 319 (-4.7A)
ZN  A   4 ( 2.3A)
ZN  A   4 (-2.2A)
SAH  A 319 (-3.9A)
 0.58A 2r3aA-1pegA:
27.1		 2r3aA-1pegA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r3a HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV39H2

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		5 ARG A 150
GLY A 149
HIS A 220
CYH A 289
LEU A 298
 None
None
SAM  A 304 (-4.9A)
ZN  A 300 ( 2.3A)
SAM  A 304 (-4.7A)
 1.25A 2r3aA-2r3aA:
47.2		 2r3aA-2r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r3a HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV39H2

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		12 ARG A 150
GLY A 151
TRP A 152
LYS A 189
THR A 192
TYR A 193
HIS A 220
TYR A 261
CYH A 287
LYS A 288
CYH A 289
LEU A 298
 None
SAM  A 304 (-3.5A)
None
SAM  A 304 (-3.9A)
SAM  A 304 (-3.6A)
SAM  A 304 (-4.2A)
SAM  A 304 (-4.9A)
SAM  A 304 (-4.9A)
ZN  A 300 ( 2.3A)
None
ZN  A 300 ( 2.3A)
SAM  A 304 (-4.7A)
 0.04A 2r3aA-2r3aA:
47.2		 2r3aA-2r3aA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5z HISTONE-LYSINE
N-METHYLTRANSFERASE
HRX

(Homo sapiens) 		PF00856
(SET) 		6 GLY A3840
HIS A3907
TYR A3944
CYH A3957
CYH A3959
LEU A3968
 SAH  A4971 ( 3.7A)
SAH  A4971 (-4.7A)
SAH  A4971 (-4.9A)
ZN  A4970 ( 2.3A)
ZN  A4970 (-2.3A)
SAH  A4971 ( 4.9A)
 0.44A 2r3aA-2w5zA:
12.9		 2r3aA-2w5zA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5z HISTONE-LYSINE
N-METHYLTRANSFERASE
HRX

(Homo sapiens) 		PF00856
(SET) 		5 GLY A3840
TYR A3883
HIS A3907
CYH A3957
CYH A3959
 SAH  A4971 ( 3.7A)
None
SAH  A4971 (-4.7A)
ZN  A4970 ( 2.3A)
ZN  A4970 (-2.3A)
 0.70A 2r3aA-2w5zA:
12.9		 2r3aA-2w5zA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn1 PEROSAMINE
SYNTHETASE

(Caulobacter
vibrioides) 		PF01041
(DegT_DnrJ_EryC1) 		5 ARG A 271
GLY A 269
LYS A 274
TYR A 288
LEU A 292
 None
 1.22A 2r3aA-3bn1A:
undetectable		 2r3aA-3bn1A:
20.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bo5 HISTONE-LYSINE
N-METHYLTRANSFERASE
SETMAR

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		5 GLY A 136
TRP A 137
HIS A 210
TYR A 248
CYH A 275
 SAH  A 305 (-3.8A)
None
None
SAH  A 305 (-4.9A)
ZN  A 304 ( 2.3A)
 1.34A 2r3aA-3bo5A:
26.2		 2r3aA-3bo5A:
30.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bo5 HISTONE-LYSINE
N-METHYLTRANSFERASE
SETMAR

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		8 GLY A 136
TRP A 137
TYR A 178
HIS A 210
TYR A 248
CYH A 273
CYH A 275
LEU A 284
 SAH  A 305 (-3.8A)
None
SAH  A 305 (-4.0A)
None
SAH  A 305 (-4.9A)
ZN  A 304 ( 2.3A)
ZN  A 304 ( 2.3A)
SAH  A 305 (-4.5A)
 0.49A 2r3aA-3bo5A:
26.2		 2r3aA-3bo5A:
30.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1

(Rattus
norvegicus) 		PF00520
(Ion_trans) 		5 GLY A 242
THR A 267
TYR A 204
CYH A 231
LEU A 208
 None
 1.28A 2r3aA-3j9jA:
undetectable		 2r3aA-3j9jA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ky9 PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF)
PF11971
(CAMSAP_CH) 		5 TYR A 541
HIS A 554
CYH A 529
LYS A 530
LEU A 536
 None
ZN  A 901 (-3.3A)
ZN  A 901 (-2.5A)
None
None
 1.41A 2r3aA-3ky9A:
undetectable		 2r3aA-3ky9A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n71 HISTONE LYSINE
METHYLTRANSFERASE
SMYD1

(Mus musculus) 		PF00856
(SET)
PF01753
(zf-MYND) 		5 GLY A  16
HIS A 206
TYR A 252
CYH A 274
CYH A 276
 None
None
SFG  A 491 (-4.8A)
ZN  A 497 (-2.2A)
ZN  A 497 (-2.5A)
 1.02A 2r3aA-3n71A:
5.4		 2r3aA-3n71A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n71 HISTONE LYSINE
METHYLTRANSFERASE
SMYD1

(Mus musculus) 		PF00856
(SET)
PF01753
(zf-MYND) 		5 HIS A 206
TYR A 252
CYH A 274
CYH A 276
LEU A 266
 None
SFG  A 491 (-4.8A)
ZN  A 497 (-2.2A)
ZN  A 497 (-2.5A)
None
 1.24A 2r3aA-3n71A:
5.4		 2r3aA-3n71A:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ooi HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC

(Homo sapiens) 		PF00856
(SET) 		9 ARG A 101
GLY A 102
TRP A 103
TYR A 146
HIS A 170
TYR A 207
CYH A 219
CYH A 221
LEU A 230
 SO4  A 235 ( 4.0A)
SAM  A 237 ( 3.7A)
None
SAM  A 237 (-4.1A)
SAM  A 237 (-4.7A)
None
ZN  A 232 ( 2.3A)
ZN  A 232 (-2.3A)
SAM  A 237 (-4.8A)
 0.72A 2r3aA-3ooiA:
19.6		 2r3aA-3ooiA:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ooi HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC

(Homo sapiens) 		PF00856
(SET) 		6 ARG A 101
TYR A 120
HIS A 170
TYR A 207
CYH A 221
LEU A 230
 SO4  A 235 ( 4.0A)
None
SAM  A 237 (-4.7A)
None
ZN  A 232 (-2.3A)
SAM  A 237 (-4.8A)
 1.46A 2r3aA-3ooiA:
19.6		 2r3aA-3ooiA:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ooi HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC

(Homo sapiens) 		PF00856
(SET) 		7 TYR A 146
HIS A 170
TYR A 207
CYH A 219
LYS A 220
CYH A 221
LEU A 230
 SAM  A 237 (-4.1A)
SAM  A 237 (-4.7A)
None
ZN  A 232 ( 2.3A)
None
ZN  A 232 (-2.3A)
SAM  A 237 (-4.8A)
 0.96A 2r3aA-3ooiA:
19.6		 2r3aA-3ooiA:
30.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ope PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L

(Homo sapiens) 		PF00856
(SET) 		7 GLY A2151
TRP A2152
TYR A2194
HIS A2218
TYR A2255
CYH A2268
CYH A2270
 SAM  A   7 (-3.4A)
None
SAM  A   7 (-3.4A)
None
None
ZN  A   1 ( 2.5A)
ZN  A   1 (-2.7A)
 0.59A 2r3aA-3opeA:
18.6		 2r3aA-3opeA:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ope PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L

(Homo sapiens) 		PF00856
(SET) 		6 TYR A2194
HIS A2218
TYR A2255
CYH A2268
LYS A2269
CYH A2270
 SAM  A   7 (-3.4A)
None
None
ZN  A   1 ( 2.5A)
None
ZN  A   1 (-2.7A)
 0.94A 2r3aA-3opeA:
18.6		 2r3aA-3opeA:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmu HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2

(Homo sapiens) 		PF00856
(SET) 		7 GLY A1561
TRP A1562
TYR A1605
HIS A1629
CYH A1678
CYH A1680
LEU A1689
 0UM  A1804 (-3.5A)
None
0UM  A1804 (-4.2A)
None
ZN  A1803 ( 2.2A)
ZN  A1803 (-2.2A)
0UM  A1804 (-4.8A)
 0.55A 2r3aA-4fmuA:
18.5		 2r3aA-4fmuA:
29.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gtv GERANYLGERANYL
TRANSFERASE TYPE-2
SUBUNIT ALPHA

(Rattus
norvegicus) 		PF01239
(PPTA) 		5 THR A 299
TYR A 296
CYH A 273
CYH A 260
LEU A 274
 None
 1.36A 2r3aA-4gtvA:
undetectable		 2r3aA-4gtvA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qeo HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH4

(Arabidopsis
thaliana) 		PF00856
(SET)
PF02182
(SAD_SRA)
PF05033
(Pre-SET) 		7 GLY A 457
TRP A 458
HIS A 552
TYR A 593
CYH A 612
CYH A 614
LEU A 623
 SAH  A 801 (-3.6A)
SAH  A 801 (-4.9A)
None
None
ZN  A 805 ( 2.4A)
ZN  A 805 ( 2.4A)
None
 0.37A 2r3aA-4qeoA:
27.6		 2r3aA-4qeoA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qeo HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH4

(Arabidopsis
thaliana) 		PF00856
(SET)
PF02182
(SAD_SRA)
PF05033
(Pre-SET) 		7 GLY A 457
TYR A 493
HIS A 552
TYR A 593
CYH A 612
CYH A 614
LEU A 623
 SAH  A 801 (-3.6A)
SAH  A 801 (-4.0A)
None
None
ZN  A 805 ( 2.4A)
ZN  A 805 ( 2.4A)
None
 0.75A 2r3aA-4qeoA:
27.6		 2r3aA-4qeoA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z4p HISTONE-LYSINE
N-METHYLTRANSFERASE
2D

(Homo sapiens) 		PF00856
(SET) 		6 GLY A5408
TYR A5451
HIS A5475
TYR A5512
CYH A5525
CYH A5527
 SAH  A5602 (-3.6A)
SAH  A5602 (-4.5A)
None
None
ZN  A5601 ( 2.2A)
ZN  A5601 ( 2.2A)
 0.74A 2r3aA-4z4pA:
13.8		 2r3aA-4z4pA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f59 HISTONE-LYSINE
N-METHYLTRANSFERASE
2C

(Homo sapiens) 		PF00856
(SET) 		5 GLY A4782
HIS A4849
TYR A4886
CYH A4899
CYH A4901
 SAH  A5002 (-3.5A)
SAH  A5002 (-4.6A)
None
ZN  A5001 ( 2.0A)
ZN  A5001 (-2.3A)
 0.33A 2r3aA-5f59A:
13.6		 2r3aA-5f59A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f59 HISTONE-LYSINE
N-METHYLTRANSFERASE
2C

(Homo sapiens) 		PF00856
(SET) 		5 GLY A4782
TYR A4825
HIS A4849
CYH A4899
CYH A4901
 SAH  A5002 (-3.5A)
SAH  A5002 (-4.5A)
SAH  A5002 (-4.6A)
ZN  A5001 ( 2.0A)
ZN  A5001 (-2.3A)
 0.80A 2r3aA-5f59A:
13.6		 2r3aA-5f59A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f6l HISTONE-LYSINE
N-METHYLTRANSFERASE
2A

(Homo sapiens) 		PF00856
(SET) 		7 GLY A3840
TYR A3883
HIS A3907
TYR A3944
CYH A3957
CYH A3959
LEU A3968
 SAH  A4001 (-3.4A)
None
SAH  A4001 (-4.9A)
SAH  A4001 (-4.9A)
ZN  A4002 ( 2.3A)
ZN  A4002 (-2.3A)
None
 0.55A 2r3aA-5f6lA:
14.0		 2r3aA-5f6lA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kjm N-LYSINE
METHYLTRANSFERASE
SMYD2

(Homo sapiens) 		PF00856
(SET)
PF01753
(zf-MYND) 		5 GLY A  16
HIS A 207
TYR A 240
CYH A 262
CYH A 264
 None
None
6TM  A 502 ( 3.6A)
ZN  A 505 (-2.3A)
ZN  A 505 (-2.4A)
 1.09A 2r3aA-5kjmA:
5.9		 2r3aA-5kjmA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kjm N-LYSINE
METHYLTRANSFERASE
SMYD2

(Homo sapiens) 		PF00856
(SET)
PF01753
(zf-MYND) 		5 HIS A 207
TYR A 240
CYH A 262
CYH A 264
LEU A 254
 None
6TM  A 502 ( 3.6A)
ZN  A 505 (-2.3A)
ZN  A 505 (-2.4A)
None
 1.29A 2r3aA-5kjmA:
5.9		 2r3aA-5kjmA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsu HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2

(Homo sapiens) 		PF00856
(SET) 		9 ARG A1073
GLY A1074
TRP A1075
TYR A1118
HIS A1142
TYR A1179
CYH A1191
CYH A1193
LEU A1202
 None
SAM  A1304 ( 3.2A)
None
SAM  A1304 (-3.8A)
SAM  A1304 (-4.6A)
SAM  A1304 (-4.1A)
ZN  A1301 ( 2.3A)
ZN  A1301 (-2.3A)
SAM  A1304 ( 4.7A)
 0.49A 2r3aA-5lsuA:
20.4		 2r3aA-5lsuA:
28.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsu HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2

(Homo sapiens) 		PF00856
(SET) 		6 GLY A1074
TRP A1075
TYR A1118
HIS A1142
TYR A1179
CYH A1193
 SAM  A1304 ( 3.2A)
None
SAM  A1304 (-3.8A)
SAM  A1304 (-4.6A)
SAM  A1304 (-4.1A)
ZN  A1301 (-2.3A)
 1.42A 2r3aA-5lsuA:
20.4		 2r3aA-5lsuA:
28.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tuy HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		5 GLY A1049
TRP A1050
HIS A1113
TYR A1154
CYH A1168
 SAM  A1505 ( 3.9A)
None
SAM  A1505 (-4.7A)
SAM  A1505 (-4.9A)
ZN  A1504 (-2.2A)
 1.42A 2r3aA-5tuyA:
28.1		 2r3aA-5tuyA:
35.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tuy HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		7 GLY A1049
TRP A1050
TYR A1085
HIS A1113
TYR A1154
CYH A1168
CYH A1170
 SAM  A1505 ( 3.9A)
None
SAM  A1505 (-4.0A)
SAM  A1505 (-4.7A)
SAM  A1505 (-4.9A)
ZN  A1504 (-2.2A)
ZN  A1504 (-2.2A)
 0.41A 2r3aA-5tuyA:
28.1		 2r3aA-5tuyA:
35.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vsd HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1

(Homo sapiens) 		PF00856
(SET)
PF05033
(Pre-SET) 		7 GLY A1137
TRP A1138
TYR A1173
HIS A1201
TYR A1242
CYH A1256
CYH A1258
 SAM  A3001 (-3.6A)
None
SAM  A3001 (-4.0A)
SAM  A3001 (-4.6A)
SAM  A3001 (-4.8A)
ZN  A3005 ( 2.4A)
ZN  A3005 (-2.3A)
 0.41A 2r3aA-5vsdA:
28.2		 2r3aA-5vsdA:
35.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxg -

(-) 		no annotation 5 GLY A  46
THR A  39
HIS A  83
CYH A  65
CYH A  62
 None
None
ZN  A 505 (-3.3A)
ZN  A 505 (-2.3A)
ZN  A 505 (-2.3A)
 1.40A 2r3aA-5xxgA:
5.7		 2r3aA-5xxgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cen HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3

(Homo sapiens) 		no annotation 9 ARG A1155
GLY A1156
TRP A1157
TYR A1200
HIS A1224
TYR A1261
CYH A1273
CYH A1275
LEU A1284
 None
SAM  A1301 (-3.6A)
None
SAM  A1301 (-3.9A)
None
SAM  A1301 (-4.9A)
ZN  A1304 ( 2.3A)
ZN  A1304 (-2.3A)
SAM  A1301 (-4.6A)
 0.62A 2r3aA-6cenA:
20.2		 2r3aA-6cenA:
29.04