SIMILAR PATTERNS OF AMINO ACIDS FOR 2QQT_A_AINA596

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1d7w MYELOPEROXIDASE

(Homo sapiens) 		PF03098
(An_peroxidase) 		4 HIS A  95
ARG C 239
GLU C 242
PHE C 366
 CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
 0.66A 2qqtA-1d7wA:
3.3		 2qqtA-1d7wA:
38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1d7w MYELOPEROXIDASE

(Homo sapiens) 		PF03098
(An_peroxidase) 		4 HIS A  95
ARG C 239
GLU C 242
PRO C 220
 CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
 1.24A 2qqtA-1d7wA:
3.3		 2qqtA-1d7wA:
38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5i DEACETOXYCEPHALOSPOR
IN C SYNTHASE

(Streptomyces
clavuligerus) 		PF03171
(2OG-FeII_Oxy) 		4 ARG A  24
GLU A  21
PHE A   8
PRO A   6
 None
 1.00A 2qqtA-1e5iA:
0.0		 2qqtA-1e5iA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 ARG B 816
GLU B 845
GLN B 891
PRO B 773
 None
 0.94A 2qqtA-1gl9B:
undetectable		 2qqtA-1gl9B:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvf TAGATOSE-BISPHOSPHAT
E ALDOLASE AGAY

(Escherichia
coli) 		PF01116
(F_bP_aldolase) 		4 ARG A 198
GLU A 199
GLN A 158
PRO A 157
 None
 1.49A 2qqtA-1gvfA:
0.0		 2qqtA-1gvfA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h9e LAMINA-ASSOCIATED
POLYPEPTIDE 2

(Homo sapiens) 		PF08198
(Thymopoietin) 		4 ARG A  49
GLU A   5
PHE A   3
PRO A   7
 None
 1.33A 2qqtA-1h9eA:
undetectable		 2qqtA-1h9eA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq0 ARGINYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 HIS A 427
PHE A 465
GLN A 474
PRO A 471
 None
 1.33A 2qqtA-1iq0A:
0.0		 2qqtA-1iq0A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ji4 NEUTROPHIL-ACTIVATIN
G PROTEIN A

(Helicobacter
pylori) 		PF00210
(Ferritin) 		4 ARG A  57
GLU A  56
GLN A  11
PRO A  65
 None
FE  A 807 (-2.6A)
None
None
 1.47A 2qqtA-1ji4A:
0.7		 2qqtA-1ji4A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pix GLUTACONYL-COA
DECARBOXYLASE A
SUBUNIT

(Acidaminococcus
fermentans) 		PF01039
(Carboxyl_trans) 		4 ARG A 164
PHE A  82
GLN A  85
PRO A  84
 None
 1.47A 2qqtA-1pixA:
0.0		 2qqtA-1pixA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pix GLUTACONYL-COA
DECARBOXYLASE A
SUBUNIT

(Acidaminococcus
fermentans) 		PF01039
(Carboxyl_trans) 		4 GLU A 126
PHE A  82
GLN A  85
PRO A  84
 None
 1.37A 2qqtA-1pixA:
0.0		 2qqtA-1pixA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sjw NOGALONIC ACID
METHYL ESTER CYCLASE

(Streptomyces
nogalater) 		PF07366
(SnoaL) 		4 HIS A  39
PHE A 125
GLN A 105
PRO A 123
 None
NGV  A 333 (-4.5A)
NGV  A 333 (-2.8A)
NGV  A 333 (-4.5A)
 1.04A 2qqtA-1sjwA:
undetectable		 2qqtA-1sjwA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1un9 DIHYDROXYACETONE
KINASE

(Citrobacter
freundii) 		PF02733
(Dak1)
PF02734
(Dak2) 		4 HIS A  61
PHE A   4
GLN A 200
PRO A 199
 2HA  A1554 (-3.7A)
None
None
None
 1.33A 2qqtA-1un9A:
0.0		 2qqtA-1un9A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdt ELONGATION FACTOR G
HOMOLOG

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03764
(EFG_IV)
PF14492
(EFG_II) 		4 HIS A 177
GLU A 270
PHE A 238
PRO A 249
 None
 1.43A 2qqtA-1wdtA:
undetectable		 2qqtA-1wdtA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afh NITROGENASE
MOLYBDENUM-IRON
PROTEIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 HIS B 297
GLU B 231
PHE B 237
PRO B 257
 None
 1.09A 2qqtA-2afhB:
undetectable		 2qqtA-2afhB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE

(Leuconostoc
mesenteroides) 		PF00479
(G6PD_N)
PF02781
(G6PD_C) 		4 HIS A 178
GLU A 147
PHE A 123
PRO A 120
 None
 1.32A 2qqtA-2dpgA:
undetectable		 2qqtA-2dpgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 ARG A  73
PHE A 691
GLN A  76
PRO A 687
 None
 1.47A 2qqtA-2e7zA:
undetectable		 2qqtA-2e7zA:
20.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gjm LACTOPEROXIDASE

(Bubalus bubalis) 		PF03098
(An_peroxidase) 		6 HIS A  95
ARG A 239
GLU A 242
PHE A 366
GLN A 408
PRO A 409
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
None
 0.38A 2qqtA-2gjmA:
65.6		 2qqtA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gza TYPE IV SECRETION
SYSTEM PROTEIN
VIRB11

(Brucella suis) 		PF00437
(T2SSE) 		4 HIS A 222
GLU A 111
PHE A 226
PRO A 212
 None
 1.29A 2qqtA-2gzaA:
undetectable		 2qqtA-2gzaA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nbr GAMMA-CRYSTALLIN C

(Homo sapiens) 		PF00030
(Crystall) 		4 GLU A  61
PHE A  11
GLN A  67
PRO A  63
 None
 1.27A 2qqtA-2nbrA:
undetectable		 2qqtA-2nbrA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p28 INTEGRIN BETA-2

(Homo sapiens) 		PF17205
(PSI_integrin)
no annotation 		4 ARG B 426
GLU B 424
GLN B 422
PRO A  59
 None
 1.27A 2qqtA-2p28B:
undetectable		 2qqtA-2p28B:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qde MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Aromatoleum
aromaticum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 HIS A 331
GLU A 325
PHE A 163
GLN A 324
 None
 1.38A 2qqtA-2qdeA:
undetectable		 2qqtA-2qdeA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a6p EXPORTIN-5

(Homo sapiens) 		PF08389
(Xpo1) 		4 ARG A 126
GLU A 127
GLN A 130
PRO A 129
 None
 1.41A 2qqtA-3a6pA:
undetectable		 2qqtA-3a6pA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ck6 PUTATIVE MEMBRANE
TRANSPORT PROTEIN

(Vibrio
parahaemolyticus) 		PF01544
(CorA) 		4 HIS A  32
ARG A 119
PHE A  10
PRO A 128
 CL  A 250 (-4.3A)
None
None
None
 1.45A 2qqtA-3ck6A:
undetectable		 2qqtA-3ck6A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgw PUTATIVE
PHOSPHOLIPASE B-LIKE
2

(Mus musculus) 		PF04916
(Phospholip_B) 		4 ARG A 287
GLU A 288
GLN A 186
PRO A 182
 None
 1.46A 2qqtA-3fgwA:
undetectable		 2qqtA-3fgwA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3foa TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N) 		4 GLU A  47
PHE A  65
GLN A  56
PRO A  57
 None
 1.49A 2qqtA-3foaA:
undetectable		 2qqtA-3foaA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hig AMILORIDE-SENSITIVE
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 HIS A 340
ARG A 345
PHE A 701
GLN A 583
 None
 1.40A 2qqtA-3higA:
undetectable		 2qqtA-3higA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuu PUTATIVE
METALLOPEPTIDASE

(Chelativorans
sp. BNC1) 		PF07171
(MlrC_C)
PF07364
(DUF1485) 		4 HIS A 233
PHE A 469
GLN A 466
PRO A 464
 None
 1.48A 2qqtA-3iuuA:
undetectable		 2qqtA-3iuuA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2n TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		4 GLU U  47
PHE U  65
GLN U  56
PRO U  57
 None
 1.49A 2qqtA-3j2nU:
undetectable		 2qqtA-3j2nU:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4x NOL1/NOP2/SUN FAMILY
PROTEIN

(Enterococcus
faecium) 		PF01189
(Methyltr_RsmB-F)
PF13636
(Methyltranf_PUA)
PF17125
(Methyltr_RsmF_N)
PF17126
(RsmF_methylt_CI) 		4 HIS A  82
ARG A 152
PHE A 449
PRO A 450
 None
 1.02A 2qqtA-3m4xA:
undetectable		 2qqtA-3m4xA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qp9 TYPE I POLYKETIDE
SYNTHASE PIKAII

(Streptomyces
venezuelae) 		PF08659
(KR) 		4 ARG A 361
PHE A 400
GLN A 407
PRO A 149
 None
 1.07A 2qqtA-3qp9A:
undetectable		 2qqtA-3qp9A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wst PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Caenorhabditis
elegans) 		PF13649
(Methyltransf_25) 		4 HIS A 300
GLU A 140
PHE A  46
PRO A 171
 None
SAH  A 701 (-4.4A)
None
None
 1.49A 2qqtA-3wstA:
undetectable		 2qqtA-3wstA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ilk STARVATION SENSING
PROTEIN RSPB

(Escherichia
coli) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 HIS A  47
GLU A 324
PHE A 323
GLN A 327
 None
 0.99A 2qqtA-4ilkA:
undetectable		 2qqtA-4ilkA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb1 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Pseudomonas
aeruginosa) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 ARG A 314
PHE A 240
GLN A 321
PRO A 334
 None
None
GOL  A 408 (-2.7A)
GOL  A 408 (-3.9A)
 1.17A 2qqtA-4jb1A:
undetectable		 2qqtA-4jb1A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE

(Pseudomonas
syringae group
genomosp. 3) 		PF13229
(Beta_helix) 		4 ARG A 186
GLU A 213
GLN A 189
PRO A 229
 None
MLY  A 191 ( 4.8A)
None
None
 1.32A 2qqtA-4nk6A:
undetectable		 2qqtA-4nk6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ozy POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE

(Pseudomonas
syringae group
genomosp. 3) 		PF13229
(Beta_helix) 		4 ARG A 186
GLU A 213
GLN A 189
PRO A 229
 None
MLY  A 191 ( 4.8A)
None
None
 1.26A 2qqtA-4ozyA:
undetectable		 2qqtA-4ozyA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgk FATTY ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		4 GLU A 207
PHE A 182
GLN A 120
PRO A 121
 None
 1.05A 2qqtA-4qgkA:
undetectable		 2qqtA-4qgkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qn3 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 ARG A  25
GLU A  28
PHE A 389
GLN A 387
 None
 1.41A 2qqtA-4qn3A:
undetectable		 2qqtA-4qn3A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE

(Bacillus
licheniformis) 		PF09924
(DUF2156) 		4 GLU A 668
PHE A 672
GLN A 669
PRO A 670
 None
 1.40A 2qqtA-4v36A:
undetectable		 2qqtA-4v36A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 HIS B 153
ARG B 109
GLN B   6
PRO B 106
 None
 1.33A 2qqtA-4zdhB:
undetectable		 2qqtA-4zdhB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmx D-ALANINE--D-ALANINE
LIGASE

(Acinetobacter
baumannii) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 241
PHE A 188
GLN A 192
PRO A 193
 None
 1.08A 2qqtA-5dmxA:
undetectable		 2qqtA-5dmxA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 GLU A 462
PHE A 464
GLN A 489
PRO A 490
 CYT  A 602 (-2.8A)
None
None
None
 1.39A 2qqtA-5ereA:
0.1		 2qqtA-5ereA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5euo PF6 TCR BETA CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 HIS F 150
ARG F 106
GLN F   4
PRO F 103
 None
 1.35A 2qqtA-5euoF:
undetectable		 2qqtA-5euoF:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3s INOSITOL
MONOPHOSPHATASE
FAMILY PROTEIN

(Staphylococcus
aureus) 		PF00459
(Inositol_P) 		4 HIS A 266
PHE A 209
GLN A 205
PRO A 206
 None
 1.11A 2qqtA-5i3sA:
undetectable		 2qqtA-5i3sA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB

(Saccharomyces
cerevisiae) 		no annotation 4 ARG 7 757
GLU 7 564
PHE 7 565
PRO 7 585
 None
 1.36A 2qqtA-5oqm7:
undetectable		 2qqtA-5oqm7:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u56 MACROPHAGE GROWTH
LOCUS A

(Francisella
tularensis) 		PF13417
(GST_N_3) 		4 ARG A 142
GLU A 141
GLN A  88
PRO A  83
 GOL  A 302 ( 4.3A)
None
1PE  A 303 (-3.9A)
None
 1.48A 2qqtA-5u56A:
undetectable		 2qqtA-5u56A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w99 PBTD

(Planobispora
rosea) 		no annotation 4 HIS A  38
ARG A 113
GLU A  92
GLN A  93
 None
 1.39A 2qqtA-5w99A:
undetectable		 2qqtA-5w99A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6caj TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA

(Homo sapiens) 		no annotation 4 ARG C 172
GLU C  32
PHE C 272
PRO C 270
 None
 1.29A 2qqtA-6cajC:
1.8		 2qqtA-6cajC:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6erc PEROXINECTIN A

(Dictyostelium
discoideum) 		no annotation 4 HIS A 101
ARG A 233
GLU A 236
PHE A 352
 None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.98A 2qqtA-6ercA:
39.5		 2qqtA-6ercA:
9.17