SIMILAR PATTERNS OF AMINO ACIDS FOR 2QPU_B_QPSB3000
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1amy | 1,4-ALPHA-D-GLUCANGLUCANOHYDROLASE (Hordeum vulgare) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 6 | LYS A 373VAL A 380HIS A 393ASP A 396ALA A 398TRP A 400 | None | 0.50A | 2qpuB-1amyA:17.1 | 2qpuB-1amyA:75.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qps | ALPHA-AMYLASE TYPE AISOZYME (Hordeum vulgare) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 8 | LYS A 375ASP A 381VAL A 382THR A 392HIS A 395ASP A 398ALA A 400TRP A 402 | None | 0.73A | 2qpuB-2qpsA:69.9 | 2qpuB-2qpsA:99.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kwl | UNCHARACTERIZEDPROTEIN (Helicobacterpylori) |
no annotation | 5 | TYR A 442ASP A 246VAL A 247ASP A 310ALA A 242 | None | 1.32A | 2qpuB-3kwlA:1.0 | 2qpuB-3kwlA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2x | UNCHARACTERIZEDPROTEIN YAGE (Escherichiacoli) |
PF00701(DHDPS) | 5 | ASP A 110VAL A 85HIS A 103ASP A 77ALA A 72 | None | 1.38A | 2qpuB-3n2xA:6.7 | 2qpuB-3n2xA:21.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3wn6 | ALPHA-AMYLASE (Oryza sativa) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 7 | LYS A 398TYR A 403ASP A 404VAL A 405HIS A 418ALA A 423TRP A 425 | None | 1.15A | 2qpuB-3wn6A:68.0 | 2qpuB-3wn6A:76.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oe7 | PROBABLE2-KETO-3-DEOXY-GALACTONATE ALDOLASE YAGE (Escherichiacoli) |
PF00701(DHDPS) | 5 | ASP A 110VAL A 85HIS A 103ASP A 77ALA A 72 | NoneNoneEDO A 405 ( 3.9A)NoneEDO A 405 (-3.5A) | 1.40A | 2qpuB-4oe7A:8.8 | 2qpuB-4oe7A:21.09 |