SIMILAR PATTERNS OF AMINO ACIDS FOR 2QMZ_B_LDPB502_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6a | HLA CLASS IIHISTOCOMPATIBILITYANTIGEN, DR ALPHACHAIN (Homo sapiens) |
PF00993(MHC_II_alpha)PF07654(C1-set) | 4 | GLN A 9PHE A 24PHE A 32GLY A 58 | None | 1.04A | 2qmzA-1a6aA:undetectable2qmzB-1a6aA:undetectable | 2qmzA-1a6aA:24.352qmzB-1a6aA:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c7g | TYROSINEPHENOL-LYASE (Pantoeaagglomerans) |
PF01212(Beta_elim_lyase) | 4 | GLN A 364PHE A 453PHE A 439GLY A 387 | None | 1.30A | 2qmzA-1c7gA:2.52qmzB-1c7gA:2.9 | 2qmzA-1c7gA:19.222qmzB-1c7gA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fkm | PROTEIN (GYP1P) (Saccharomycescerevisiae) |
PF00566(RabGAP-TBC) | 4 | PHE A 387PHE A 391TRP A 290GLY A 295 | None | 1.25A | 2qmzA-1fkmA:0.02qmzB-1fkmA:undetectable | 2qmzA-1fkmA:20.252qmzB-1fkmA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz4 | NAD-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 4 | GLN A 253PHE A 276PHE A 491GLY A 473 | None | 1.19A | 2qmzA-1gz4A:3.02qmzB-1gz4A:2.9 | 2qmzA-1gz4A:17.192qmzB-1gz4A:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h39 | SQUALENE--HOPENECYCLASE (Alicyclobacillusacidocaldarius) |
PF13243(SQHop_cyclase_C)PF13249(SQHop_cyclase_N) | 4 | PHE A 404PHE A 456TRP A 465GLY A 409 | None | 1.41A | 2qmzA-1h39A:undetectable2qmzB-1h39A:undetectable | 2qmzA-1h39A:16.292qmzB-1h39A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h4u | NIDOGEN-1 (Mus musculus) |
PF07474(G2F) | 4 | GLN A 505PHE A 507PHE A 486GLY A 465 | None | 1.33A | 2qmzA-1h4uA:undetectable2qmzB-1h4uA:undetectable | 2qmzA-1h4uA:23.132qmzB-1h4uA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iid | PEPTIDEN-MYRISTOYLTRANSFERASE (Saccharomycescerevisiae) |
PF01233(NMT)PF02799(NMT_C) | 4 | GLN A 287PHE A 289PHE A 276GLY A 451 | None | 1.41A | 2qmzA-1iidA:undetectable2qmzB-1iidA:undetectable | 2qmzA-1iidA:17.422qmzB-1iidA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbl | PYRUVATE PHOSPHATEDIKINASE ([Clostridium]symbiosum) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 4 | GLN A 680PHE A 566PHE A 626GLY A 666 | None | 1.09A | 2qmzA-1kblA:0.22qmzB-1kblA:0.2 | 2qmzA-1kblA:14.042qmzB-1kblA:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l0q | SURFACE LAYERPROTEIN (Methanosarcinamazei) |
PF00801(PKD)PF10282(Lactonase) | 4 | PHE A 309PHE A 326TRP A 338GLY A 341 | None | 1.17A | 2qmzA-1l0qA:0.02qmzB-1l0qA:undetectable | 2qmzA-1l0qA:19.212qmzB-1l0qA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhm | S-ADENOSYLMETHIONINEDECARBOXYLASE (Solanumtuberosum) |
PF01536(SAM_decarbox) | 4 | GLN A 332PHE A 334PHE A 289GLY A 274 | None | 1.25A | 2qmzA-1mhmA:undetectable2qmzB-1mhmA:undetectable | 2qmzA-1mhmA:21.052qmzB-1mhmA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nsv | GALACTOSE MUTAROTASE (Lactococcuslactis) |
PF01263(Aldose_epim) | 4 | GLN A 235PHE A 195PHE A 246GLY A 241 | None | 1.29A | 2qmzA-1nsvA:undetectable2qmzB-1nsvA:undetectable | 2qmzA-1nsvA:22.652qmzB-1nsvA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tl2 | PROTEIN(TACHYLECTIN-2) (Tachypleustridentatus) |
PF14517(Tachylectin) | 4 | GLN A 199PHE A 184TRP A 216GLY A 179 | NoneNoneNoneNDG A 241 (-4.7A) | 1.29A | 2qmzA-1tl2A:undetectable2qmzB-1tl2A:undetectable | 2qmzA-1tl2A:24.062qmzB-1tl2A:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6j | LANOSTEROL SYNTHASE (Homo sapiens) |
PF13243(SQHop_cyclase_C)PF13249(SQHop_cyclase_N) | 4 | PHE A 391PHE A 711TRP A 590GLY A 582 | None | 1.22A | 2qmzA-1w6jA:undetectable2qmzB-1w6jA:undetectable | 2qmzA-1w6jA:17.082qmzB-1w6jA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wac | P2 PROTEIN (Pseudomonasvirus phi6) |
PF00680(RdRP_1) | 4 | GLN A 525PHE A 526PHE A 53TRP A 575 | None | 1.34A | 2qmzA-1wacA:undetectable2qmzB-1wacA:undetectable | 2qmzA-1wacA:16.542qmzB-1wacA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr5 | GENOME POLYPROTEIN (Rhinovirus B) |
PF00680(RdRP_1) | 4 | GLN A 340PHE A 362PHE A 232GLY A 346 | None | 1.11A | 2qmzA-1xr5A:undetectable2qmzB-1xr5A:undetectable | 2qmzA-1xr5A:19.402qmzB-1xr5A:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv2 | HYPOTHETICALPROTEIN, SIMILAR TOALPHA-ACETOLACTATEDECARBOXYLASE (Staphylococcusaureus) |
PF03306(AAL_decarboxy) | 4 | GLN A 200PHE A 202PHE A 158GLY A 32 | None | 1.38A | 2qmzA-1xv2A:undetectable2qmzB-1xv2A:undetectable | 2qmzA-1xv2A:24.622qmzB-1xv2A:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv2 | HYPOTHETICALPROTEIN, SIMILAR TOALPHA-ACETOLACTATEDECARBOXYLASE (Staphylococcusaureus) |
PF03306(AAL_decarboxy) | 4 | GLN A 207PHE A 205PHE A 109GLY A 166 | None | 1.25A | 2qmzA-1xv2A:undetectable2qmzB-1xv2A:undetectable | 2qmzA-1xv2A:24.622qmzB-1xv2A:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y9g | EXO-INULINASE (Aspergillusawamori) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | PHE A 280PHE A 230TRP A 240GLY A 244 | None | 1.27A | 2qmzA-1y9gA:undetectable2qmzB-1y9gA:undetectable | 2qmzA-1y9gA:18.572qmzB-1y9gA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4x | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF00801(PKD) | 4 | PHE A 11PHE A 26TRP A 43GLY A 46 | None | 1.13A | 2qmzA-2c4xA:undetectable2qmzB-2c4xA:undetectable | 2qmzA-2c4xA:22.742qmzB-2c4xA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2co8 | NEDD9 INTERACTINGPROTEIN WITHCALPONIN HOMOLOGYAND LIM DOMAINS (Homo sapiens) |
PF00412(LIM) | 4 | GLN A 59PHE A 66PHE A 43GLY A 35 | None | 1.43A | 2qmzA-2co8A:undetectable2qmzB-2co8A:undetectable | 2qmzA-2co8A:16.592qmzB-2co8A:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dar | PDZ AND LIM DOMAINPROTEIN 5 (Homo sapiens) |
PF00412(LIM) | 4 | GLN A 14PHE A 66PHE A 52GLY A 44 | None | 1.08A | 2qmzA-2darA:undetectable2qmzB-2darA:undetectable | 2qmzA-2darA:17.472qmzB-2darA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9q | CYTOCHROME P450 2D6 (Homo sapiens) |
PF00067(p450) | 4 | PHE A 420PHE A 433TRP A 409GLY A 367 | None | 1.25A | 2qmzA-2f9qA:undetectable2qmzB-2f9qA:undetectable | 2qmzA-2f9qA:19.422qmzB-2f9qA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g29 | NITRATE TRANSPORTPROTEIN NRTA (Synechocystissp.) |
PF13379(NMT1_2) | 4 | GLN A 255PHE A 335PHE A 342GLY A 260 | None | 1.18A | 2qmzA-2g29A:undetectable2qmzB-2g29A:undetectable | 2qmzA-2g29A:19.462qmzB-2g29A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gpc | IRON SUPEROXIDEDISMUTASE (Trypanosomacruzi) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | GLN A 193PHE A 77PHE A 73TRP A 126 | None | 1.06A | 2qmzA-2gpcA:undetectable2qmzB-2gpcA:undetectable | 2qmzA-2gpcA:20.592qmzB-2gpcA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iiz | MELANIN BIOSYNTHESISPROTEIN TYRA,PUTATIVE (Shewanellaoneidensis) |
PF04261(Dyp_perox) | 4 | GLN A 308PHE A 305PHE A 174TRP A 70 | None | 1.32A | 2qmzA-2iizA:undetectable2qmzB-2iizA:undetectable | 2qmzA-2iizA:21.562qmzB-2iizA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m2a | FKBP-TYPE 16 KDAPEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Escherichiacoli) |
PF00254(FKBP_C) | 4 | GLN A 80PHE A 82PHE A 87GLY A 111 | None | 1.36A | 2qmzA-2m2aA:undetectable2qmzB-2m2aA:undetectable | 2qmzA-2m2aA:25.132qmzB-2m2aA:25.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nya | PERIPLASMIC NITRATEREDUCTASE (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | PHE A 508PHE A 594TRP A 118GLY A 379 | None | 1.41A | 2qmzA-2nyaA:undetectable2qmzB-2nyaA:2.1 | 2qmzA-2nyaA:15.382qmzB-2nyaA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfw | CUPIN 2, CONSERVEDBARREL DOMAINPROTEIN (Shewanellafrigidimarina) |
PF07883(Cupin_2) | 4 | GLN A 55PHE A 103PHE A 110GLY A 46 | EDO A 116 (-3.7A)NoneNoneNone | 1.43A | 2qmzA-2pfwA:undetectable2qmzB-2pfwA:undetectable | 2qmzA-2pfwA:19.812qmzB-2pfwA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0f | RNA URIDYLYLTRANSFERASE (Trypanosomabrucei) |
PF03828(PAP_assoc) | 4 | GLN A 257PHE A 252PHE A 248TRP A 293 | None | 1.36A | 2qmzA-2q0fA:undetectable2qmzB-2q0fA:undetectable | 2qmzA-2q0fA:21.922qmzB-2q0fA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q2r | GLUCOKINASE 1,PUTATIVE (Trypanosomacruzi) |
PF02685(Glucokinase) | 4 | GLN A 348PHE A 152PHE A 148GLY A 136 | None | 1.40A | 2qmzA-2q2rA:undetectable2qmzB-2q2rA:undetectable | 2qmzA-2q2rA:21.432qmzB-2q2rA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rt5 | MSX2-INTERACTINGPROTEIN (Homo sapiens) |
PF07744(SPOC) | 4 | GLN A3627PHE A3629PHE A3634GLY A3562 | None | 0.72A | 2qmzA-2rt5A:undetectable2qmzB-2rt5A:undetectable | 2qmzA-2rt5A:20.642qmzB-2rt5A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0q | ALCALIGINBIOSYNTHESIS PROTEIN (Bordetellabronchiseptica) |
PF04183(IucA_IucC)PF06276(FhuF) | 4 | PHE A 512PHE A 508TRP A 531GLY A 536 | None | 1.33A | 2qmzA-2x0qA:undetectable2qmzB-2x0qA:undetectable | 2qmzA-2x0qA:18.052qmzB-2x0qA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xgo | XCOGT (Xanthomonascampestris) |
PF13432(TPR_16)PF13844(Glyco_transf_41) | 4 | PHE A 287PHE A 210TRP A 312GLY A 553 | None | 1.43A | 2qmzA-2xgoA:4.12qmzB-2xgoA:4.1 | 2qmzA-2xgoA:18.302qmzB-2xgoA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3c | MALTOSE-BINDINGPERIPLASMIC PROTEIN,LINKER,MITOCHONDRIALINTERMEMBRANE SPACEIMPORT AND ASSEMBLYPROTEIN 40 (Escherichiacoli;Saccharomycescerevisiae;syntheticconstruct) |
PF06747(CHCH)PF13416(SBP_bac_8) | 4 | PHE A 415PHE A 411TRP A 394GLY A 400 | None | 1.05A | 2qmzA-3a3cA:undetectable2qmzB-3a3cA:undetectable | 2qmzA-3a3cA:20.142qmzB-3a3cA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmn | PUTATIVE HYDROLASE (Chloroflexusaurantiacus) |
PF10103(Zincin_2) | 4 | PHE A 120PHE A 116TRP A 46GLY A 155 | None | 1.35A | 2qmzA-3cmnA:undetectable2qmzB-3cmnA:undetectable | 2qmzA-3cmnA:19.072qmzB-3cmnA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e20 | EUKARYOTIC PEPTIDECHAIN RELEASE FACTORSUBUNIT 1 (Schizosaccharomycespombe) |
no annotation | 4 | GLN C 400PHE C 288PHE C 287GLY C 406 | None | 1.38A | 2qmzA-3e20C:undetectable2qmzB-3e20C:undetectable | 2qmzA-3e20C:20.152qmzB-3e20C:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 4 | PHE A 149PHE A 150TRP A 570GLY A 527 | None | 1.33A | 2qmzA-3eqnA:undetectable2qmzB-3eqnA:undetectable | 2qmzA-3eqnA:16.692qmzB-3eqnA:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 4 | PHE A 149PHE A 150TRP A 570GLY A 528 | None | 1.15A | 2qmzA-3eqnA:undetectable2qmzB-3eqnA:undetectable | 2qmzA-3eqnA:16.692qmzB-3eqnA:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3esf | IRON-CONTAININGSUPEROXIDE DISMUTASEB2 (Trypanosomabrucei) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | GLN A 194PHE A 78PHE A 74TRP A 127 | None | 1.03A | 2qmzA-3esfA:undetectable2qmzB-3esfA:undetectable | 2qmzA-3esfA:20.502qmzB-3esfA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f5b | AMINOGLYCOSIDEN(6')ACETYLTRANSFERASE (Legionellapneumophila) |
PF13523(Acetyltransf_8) | 4 | GLN A 111PHE A 12PHE A 73GLY A 105 | None | 1.22A | 2qmzA-3f5bA:undetectable2qmzB-3f5bA:undetectable | 2qmzA-3f5bA:21.942qmzB-3f5bA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fca | CYSTEINE SYNTHASE (Thermusthermophilus) |
PF00291(PALP) | 4 | GLN A 132PHE A 133PHE A 216GLY A 110 | None | 1.31A | 2qmzA-3fcaA:undetectable2qmzB-3fcaA:undetectable | 2qmzA-3fcaA:21.782qmzB-3fcaA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fca | CYSTEINE SYNTHASE (Thermusthermophilus) |
PF00291(PALP) | 4 | GLN A 132PHE A 133PHE A 216GLY A 113 | None | 1.40A | 2qmzA-3fcaA:undetectable2qmzB-3fcaA:undetectable | 2qmzA-3fcaA:21.782qmzB-3fcaA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gf6 | UNCHARACTERIZEDBACTERIALLIPOPROTEIN (Bacteroidesthetaiotaomicron) |
PF12956(DUF3845) | 4 | GLN A 119PHE A 162PHE A 213GLY A 112 | None | 1.28A | 2qmzA-3gf6A:undetectable2qmzB-3gf6A:undetectable | 2qmzA-3gf6A:22.642qmzB-3gf6A:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hxw | ALANYL-TRNASYNTHETASE (Escherichiacoli) |
PF01411(tRNA-synt_2c) | 4 | GLN A 45PHE A 46PHE A 98GLY A 94 | None | 1.41A | 2qmzA-3hxwA:undetectable2qmzB-3hxwA:undetectable | 2qmzA-3hxwA:17.412qmzB-3hxwA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6r | DIHYDROOROTATEDEHYDROGENASEHOMOLOG,MITOCHONDRIAL (Plasmodiumfalciparum) |
PF01180(DHO_dh) | 4 | GLN A 526PHE A 244PHE A 217GLY A 453 | None | 1.24A | 2qmzA-3i6rA:undetectable2qmzB-3i6rA:undetectable | 2qmzA-3i6rA:19.152qmzB-3i6rA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 4 | GLN A 171PHE A 169PHE A 80GLY A 220 | None | 1.23A | 2qmzA-3kxwA:3.32qmzB-3kxwA:3.7 | 2qmzA-3kxwA:16.952qmzB-3kxwA:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 4 | GLN A 171PHE A 169PHE A 80GLY A 223 | NoneNoneNone1ZZ A 589 (-3.8A) | 1.12A | 2qmzA-3kxwA:3.32qmzB-3kxwA:3.7 | 2qmzA-3kxwA:16.952qmzB-3kxwA:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n7x | CAPSID PROTEIN (Decapodpenstyldensovirus1) |
PF16530(IHHNV_capsid) | 4 | GLN A 263PHE A 265PHE A 197GLY A 157 | None | 1.42A | 2qmzA-3n7xA:undetectable2qmzB-3n7xA:undetectable | 2qmzA-3n7xA:21.412qmzB-3n7xA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3npe | 9-CIS-EPOXYCAROTENOID DIOXYGENASE 1,CHLOROPLASTIC (Zea mays) |
PF03055(RPE65) | 4 | GLN A 202PHE A 211PHE A 230GLY A 237 | None | 1.37A | 2qmzA-3npeA:undetectable2qmzB-3npeA:undetectable | 2qmzA-3npeA:18.702qmzB-3npeA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oep | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA0988 (Thermusthermophilus) |
PF02626(CT_A_B)PF02682(CT_C_D) | 4 | GLN A 156PHE A 125PHE A 123GLY A 167 | NoneGOL A 501 (-4.8A)NoneGOL A 501 ( 4.9A) | 1.33A | 2qmzA-3oepA:undetectable2qmzB-3oepA:undetectable | 2qmzA-3oepA:18.482qmzB-3oepA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p3l | CYTOCHROME P450 (Streptomycesthioluteus) |
PF00067(p450) | 4 | GLN A 91PHE A 89PHE A 85GLY A 176 | HEM A 501 (-4.3A)NoneNoneNone | 0.72A | 2qmzA-3p3lA:undetectable2qmzB-3p3lA:undetectable | 2qmzA-3p3lA:20.922qmzB-3p3lA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8a | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF13468(Glyoxalase_3) | 4 | GLN A 186PHE A 189PHE A 270GLY A 42 | None | 1.01A | 2qmzA-3p8aA:undetectable2qmzB-3p8aA:undetectable | 2qmzA-3p8aA:19.332qmzB-3p8aA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rom | ADP-RIBOSYL CYCLASE1 (Homo sapiens) |
PF02267(Rib_hydrolayse) | 4 | GLN A 139PHE A 135PHE A 284TRP A 241 | None | 1.41A | 2qmzA-3romA:5.32qmzB-3romA:5.3 | 2qmzA-3romA:21.322qmzB-3romA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ros | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Lactobacillusacidophilus) |
PF00171(Aldedh) | 4 | GLN A 137PHE A 426TRP A 418GLY A 231 | None | 1.39A | 2qmzA-3rosA:3.32qmzB-3rosA:3.2 | 2qmzA-3rosA:18.562qmzB-3rosA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8i | PURINE NUCLEOSIDASE,(IUNH-2) (Sulfolobussolfataricus) |
PF01156(IU_nuc_hydro) | 4 | PHE A 48PHE A 213TRP A 87GLY A 83 | None | 1.42A | 2qmzA-3t8iA:3.62qmzB-3t8iA:3.6 | 2qmzA-3t8iA:22.012qmzB-3t8iA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tav | METHIONINEAMINOPEPTIDASE (Mycobacteroidesabscessus) |
PF00557(Peptidase_M24) | 4 | GLN A 170PHE A 171PHE A 175GLY A 163 | None | 1.37A | 2qmzA-3tavA:undetectable2qmzB-3tavA:undetectable | 2qmzA-3tavA:21.682qmzB-3tavA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tze | TRYPTOPHANYL-TRNASYNTHETASE (Encephalitozooncuniculi) |
PF00579(tRNA-synt_1b) | 4 | GLN A 232PHE A 202TRP A 128GLY A 88 | TRP A 386 (-3.2A)NoneNoneTRP A 386 ( 4.0A) | 1.22A | 2qmzA-3tzeA:undetectable2qmzB-3tzeA:undetectable | 2qmzA-3tzeA:21.482qmzB-3tzeA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uw2 | PHOSPHOGLUCOMUTASE/PHOSPHOMANNOMUTASEFAMILY PROTEIN (Burkholderiathailandensis) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | GLN A 264PHE A 268PHE A 333GLY A 343 | None | 1.13A | 2qmzA-3uw2A:undetectable2qmzB-3uw2A:1.4 | 2qmzA-3uw2A:19.502qmzB-3uw2A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x43 | O-UREIDO-L-SERINESYNTHASE (Streptomyceslavendulae) |
PF00291(PALP) | 4 | GLN A 142PHE A 143PHE A 226GLY A 123 | None | 1.36A | 2qmzA-3x43A:undetectable2qmzB-3x43A:undetectable | 2qmzA-3x43A:21.162qmzB-3x43A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x43 | O-UREIDO-L-SERINESYNTHASE (Streptomyceslavendulae) |
PF00291(PALP) | 4 | GLN A 142PHE A 143PHE A 226GLY A 124 | None | 1.05A | 2qmzA-3x43A:undetectable2qmzB-3x43A:undetectable | 2qmzA-3x43A:21.162qmzB-3x43A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g10 | GLUTATHIONES-TRANSFERASEHOMOLOG (Sphingomonaspaucimobilis) |
PF13417(GST_N_3)PF16865(GST_C_5) | 4 | PHE A 168PHE A 164TRP A 192GLY A 136 | None | 1.24A | 2qmzA-4g10A:undetectable2qmzB-4g10A:undetectable | 2qmzA-4g10A:20.362qmzB-4g10A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl3 | PUTATIVEGLUCOAMYLASE (Bacteroidesuniformis) |
PF10091(Glycoamylase) | 4 | PHE A 191PHE A 192TRP A 209GLY A 146 | None | 0.83A | 2qmzA-4gl3A:undetectable2qmzB-4gl3A:undetectable | 2qmzA-4gl3A:18.312qmzB-4gl3A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxb | SORTING NEXIN-17 (Homo sapiens) |
no annotation | 4 | GLN A 227PHE A 175TRP A 236GLY A 126 | NoneNoneGOL A 401 (-3.8A)None | 1.26A | 2qmzA-4gxbA:undetectable2qmzB-4gxbA:undetectable | 2qmzA-4gxbA:22.702qmzB-4gxbA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hhr | ALPHA-DIOXYGENASE (Arabidopsisthaliana) |
PF03098(An_peroxidase) | 4 | PHE A 556PHE A 549TRP A 47GLY A 335 | None | 1.41A | 2qmzA-4hhrA:undetectable2qmzB-4hhrA:undetectable | 2qmzA-4hhrA:16.412qmzB-4hhrA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jc8 | HOPS COMPONENT VPS33 (Chaetomiumthermophilum) |
PF00995(Sec1) | 4 | GLN A 11PHE A 7PHE A 605GLY A 178 | None | 1.16A | 2qmzA-4jc8A:4.22qmzB-4jc8A:4.0 | 2qmzA-4jc8A:16.872qmzB-4jc8A:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kd6 | ENOYL-COAHYDRATASE/ISOMERASE (Paraburkholderiagraminis) |
PF00378(ECH_1) | 4 | GLN A 113PHE A 220TRP A 145GLY A 227 | None | 1.08A | 2qmzA-4kd6A:undetectable2qmzB-4kd6A:undetectable | 2qmzA-4kd6A:23.732qmzB-4kd6A:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kma | GM14141P (Drosophilamelanogaster) |
PF05076(SUFU)PF12470(SUFU_C) | 4 | GLN A 206PHE A 241PHE A 218GLY A 212 | None | 1.39A | 2qmzA-4kmaA:undetectable2qmzB-4kmaA:undetectable | 2qmzA-4kmaA:17.762qmzB-4kmaA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lq1 | 1,4-ALPHA-GLUCANBRANCHING ENZYMEGLGB (Escherichiacoli) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 4 | PHE A 560PHE A 641TRP A 628GLY A 625 | None | 1.35A | 2qmzA-4lq1A:undetectable2qmzB-4lq1A:undetectable | 2qmzA-4lq1A:18.492qmzB-4lq1A:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | GLN A1388PHE A1379TRP A1444GLY A1405 | None | 1.31A | 2qmzA-4o9xA:undetectable2qmzB-4o9xA:undetectable | 2qmzA-4o9xA:7.302qmzB-4o9xA:7.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oht | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Streptococcuspyogenes) |
PF00171(Aldedh) | 4 | GLN A 137PHE A 426TRP A 418GLY A 231 | None | 1.39A | 2qmzA-4ohtA:3.12qmzB-4ohtA:3.2 | 2qmzA-4ohtA:19.572qmzB-4ohtA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p47 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Ochrobactrumanthropi) |
PF03480(DctP) | 4 | PHE A 34PHE A 51TRP A 147GLY A 143 | None | 1.43A | 2qmzA-4p47A:undetectable2qmzB-4p47A:2.4 | 2qmzA-4p47A:21.592qmzB-4p47A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppy | PUTATIVEACYLHYDROLASE (Bacteroidesfragilis) |
PF13472(Lipase_GDSL_2) | 4 | GLN A 227PHE A 56TRP A 65GLY A 77 | None | 1.22A | 2qmzA-4ppyA:3.92qmzB-4ppyA:3.9 | 2qmzA-4ppyA:21.402qmzB-4ppyA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tz5 | PUTATIVE SECRETEDPROTEIN (Streptomycessp. SirexAA-E) |
no annotation | 4 | GLN A 150PHE A 152TRP A 444GLY A 421 | BGC A 707 ( 4.6A)BGC A 707 (-4.9A)NoneNone | 0.94A | 2qmzA-4tz5A:undetectable2qmzB-4tz5A:undetectable | 2qmzA-4tz5A:17.432qmzB-4tz5A:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8u | GLOBIN B CHAIN (Glossoscolexpaulistus) |
PF00042(Globin) | 4 | GLN B 119PHE B 28TRP B 15GLY B 22 | None | 1.20A | 2qmzA-4u8uB:undetectable2qmzB-4u8uB:undetectable | 2qmzA-4u8uB:22.132qmzB-4u8uB:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uw9 | BETA-PHOSPHOGLUCOMUTASE (Pyrococcus sp.ST04) |
PF13419(HAD_2) | 4 | PHE A 104PHE A 213TRP A 6GLY A 196 | None | 1.38A | 2qmzA-4uw9A:3.32qmzB-4uw9A:3.0 | 2qmzA-4uw9A:20.162qmzB-4uw9A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkb | YCF53-LIKE PROTEIN (Synechocystissp. PCC 6803) |
PF05419(GUN4)PF16416(GUN4_N) | 4 | GLN A 103PHE A 105PHE A 158TRP A 150 | None | 1.33A | 2qmzA-4xkbA:undetectable2qmzB-4xkbA:undetectable | 2qmzA-4xkbA:19.842qmzB-4xkbA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkb | YCF53-LIKE PROTEIN (Synechocystissp. PCC 6803) |
PF05419(GUN4)PF16416(GUN4_N) | 4 | GLN A 103PHE A 105TRP A 150GLY A 156 | None | 1.05A | 2qmzA-4xkbA:undetectable2qmzB-4xkbA:undetectable | 2qmzA-4xkbA:19.842qmzB-4xkbA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnu | INTEGRAL MEMBRANEPROTEIN-DOPAMINETRANSPORTER (Drosophilamelanogaster) |
PF00209(SNF) | 4 | PHE A 134PHE A 411TRP A 145GLY A 387 | None | 1.42A | 2qmzA-4xnuA:undetectable2qmzB-4xnuA:undetectable | 2qmzA-4xnuA:18.752qmzB-4xnuA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnu | INTEGRAL MEMBRANEPROTEIN-DOPAMINETRANSPORTER (Drosophilamelanogaster) |
PF00209(SNF) | 4 | PHE A 468PHE A 471TRP A 130GLY A 385 | None | 1.36A | 2qmzA-4xnuA:undetectable2qmzB-4xnuA:undetectable | 2qmzA-4xnuA:18.752qmzB-4xnuA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xox | 3-OXOACYL-ACPSYNTHASE (Vibrio cholerae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | GLN A 195PHE A 199PHE A 227GLY A 231 | None | 1.44A | 2qmzA-4xoxA:undetectable2qmzB-4xoxA:undetectable | 2qmzA-4xoxA:20.602qmzB-4xoxA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yhx | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEFUSION PROTEIN (Grosmanniapenicillata) |
PF00961(LAGLIDADG_1) | 4 | PHE A 42PHE A 91TRP A 61GLY A 14 | None | 1.26A | 2qmzA-4yhxA:undetectable2qmzB-4yhxA:undetectable | 2qmzA-4yhxA:21.022qmzB-4yhxA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d4w | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 690PHE A 661PHE A 705GLY A 677 | None | 1.20A | 2qmzA-5d4wA:undetectable2qmzB-5d4wA:undetectable | 2qmzA-5d4wA:12.752qmzB-5d4wA:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dwz | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Pseudomonasaeruginosa) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | GLN C 289PHE C 266PHE C 268GLY C 282 | None | 1.44A | 2qmzA-5dwzC:undetectable2qmzB-5dwzC:undetectable | 2qmzA-5dwzC:22.772qmzB-5dwzC:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7q | ACYL-COA SYNTHETASE (Streptomycesplatensis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | GLN A 220PHE A 221PHE A 300GLY A 310 | NoneSO4 A 709 (-4.7A)SO4 A 709 (-4.8A)None | 1.24A | 2qmzA-5e7qA:undetectable2qmzB-5e7qA:3.9 | 2qmzA-5e7qA:20.442qmzB-5e7qA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hf4 | DISKS LARGE HOMOLOG4 (Rattusnorvegicus) |
PF00595(PDZ) | 4 | GLN A 358PHE A 337PHE A 400GLY A 333 | None | 1.23A | 2qmzA-5hf4A:undetectable2qmzB-5hf4A:undetectable | 2qmzA-5hf4A:21.832qmzB-5hf4A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jm0 | ALPHA-MANNOSIDASE,ALPHA-MANNOSIDASE,ALPHA-MANNOSIDASE (Saccharomycescerevisiae) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 4 | GLN A 337PHE A 333TRP A 318GLY A 506 | None | 1.36A | 2qmzA-5jm0A:undetectable2qmzB-5jm0A:undetectable | 2qmzA-5jm0A:11.322qmzB-5jm0A:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m60 | BETA-1,3-GLUCANASE (Chaetomiumthermophilum) |
PF12708(Pectate_lyase_3) | 4 | PHE A 162PHE A 163TRP A 590GLY A 543 | BGC A 901 (-4.9A)NoneNoneNone | 1.40A | 2qmzA-5m60A:undetectable2qmzB-5m60A:undetectable | 2qmzA-5m60A:15.382qmzB-5m60A:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m60 | BETA-1,3-GLUCANASE (Chaetomiumthermophilum) |
PF12708(Pectate_lyase_3) | 4 | PHE A 162PHE A 163TRP A 590GLY A 544 | BGC A 901 (-4.9A)NoneNoneNone | 1.37A | 2qmzA-5m60A:undetectable2qmzB-5m60A:undetectable | 2qmzA-5m60A:15.382qmzB-5m60A:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mvd | DIHYDROOROTATEDEHYDROGENASE(QUINONE),MITOCHONDRIAL (Homo sapiens) |
PF01180(DHO_dh) | 4 | GLN A 354PHE A 115PHE A 88GLY A 279 | None | 1.20A | 2qmzA-5mvdA:undetectable2qmzB-5mvdA:undetectable | 2qmzA-5mvdA:20.812qmzB-5mvdA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ngd | PORTAL PROTEIN (Thermus virusP74-26) |
no annotation | 4 | GLN A 105PHE A 101TRP A 365GLY A 146 | None | 1.20A | 2qmzA-5ngdA:undetectable2qmzB-5ngdA:undetectable | 2qmzA-5ngdA:18.032qmzB-5ngdA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t2n | I-ONUI_E-AG007820 (syntheticconstruct) |
PF00961(LAGLIDADG_1) | 4 | PHE A 45PHE A 94TRP A 64GLY A 17 | None | 1.29A | 2qmzA-5t2nA:undetectable2qmzB-5t2nA:undetectable | 2qmzA-5t2nA:22.802qmzB-5t2nA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ue7 | PHOSPHOMANNOMUTASE (Candidaalbicans) |
PF03332(PMM) | 4 | GLN A 56PHE A 47PHE A 68GLY A 61 | None | 1.43A | 2qmzA-5ue7A:undetectable2qmzB-5ue7A:undetectable | 2qmzA-5ue7A:22.992qmzB-5ue7A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlh | LBACAS13A H328A(C2C2) (LachnospiraceaebacteriumNK4A179) |
no annotation | 4 | GLN A 914PHE A 505PHE A1249GLY A1045 | IOD A1509 ( 4.7A)NoneNoneNone | 1.42A | 2qmzA-5wlhA:undetectable2qmzB-5wlhA:undetectable | 2qmzA-5wlhA:10.072qmzB-5wlhA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvo | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
no annotation | 4 | GLN C 503PHE C 499PHE C 410GLY C 478 | None | 1.44A | 2qmzA-5wvoC:undetectable2qmzB-5wvoC:undetectable | 2qmzA-5wvoC:22.592qmzB-5wvoC:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xu5 | ENDO-1,4-BETA-MANNANASE (Rhizopusmicrosporus) |
no annotation | 4 | GLN B 71PHE B 72TRP B 62GLY B 56 | None | 1.42A | 2qmzA-5xu5B:undetectable2qmzB-5xu5B:undetectable | 2qmzA-5xu5B:17.262qmzB-5xu5B:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cpl | HLA CLASS IIHISTOCOMPATIBILITYANTIGEN, DR ALPHACHAIN (Homo sapiens) |
no annotation | 4 | GLN A 9PHE A 24PHE A 32GLY A 58 | None | 1.21A | 2qmzA-6cplA:undetectable2qmzB-6cplA:undetectable | 2qmzA-6cplA:15.912qmzB-6cplA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6egt | GLYCOPROTEIN (Rift Valleyfeverphlebovirus) |
no annotation | 4 | PHE A 990PHE A 903TRP A 855GLY A 899 | None | 1.36A | 2qmzA-6egtA:undetectable2qmzB-6egtA:undetectable | 2qmzA-6egtA:16.382qmzB-6egtA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fb3 | TENEURIN-2 (Gallus gallus) |
no annotation | 4 | PHE A2532PHE A2453TRP A2465GLY A2423 | None | 0.79A | 2qmzA-6fb3A:undetectable2qmzB-6fb3A:undetectable | 2qmzA-6fb3A:19.562qmzB-6fb3A:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fvs | CYS-LOOPLIGAND-GATED IONCHANNEL (endosymbiont ofTevniajerichonana) |
no annotation | 4 | GLN A 25PHE A 117PHE A 129GLY A 22 | None | 1.40A | 2qmzA-6fvsA:undetectable2qmzB-6fvsA:undetectable | 2qmzA-6fvsA:14.352qmzB-6fvsA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g42 | MINOR CAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 4 | GLN A 186PHE A 165PHE A 154GLY A 106 | None | 1.05A | 2qmzA-6g42A:undetectable2qmzB-6g42A:undetectable | 2qmzA-6g42A:17.242qmzB-6g42A:17.24 |