SIMILAR PATTERNS OF AMINO ACIDS FOR 2QHF_A_NCAA493
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6s | O-ACETYLSERINESULFHYDRYLASE (Salmonellaenterica) |
PF00291(PALP) | 5 | ALA A 29ILE A 22ILE A 267ALA A 269VAL A 277 | None | 1.18A | 2qhfA-1d6sA:undetectable | 2qhfA-1d6sA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgj | ALDEHYDEOXIDOREDUCTASE (Desulfovibriodesulfuricans) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | ALA A 784ILE A 883ALA A 896ALA A 819VAL A 816 | None | 1.05A | 2qhfA-1dgjA:1.7 | 2qhfA-1dgjA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dlc | DELTA-ENDOTOXINCRYIIIA (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | ALA A 517ILE A 622ILE A 538ALA A 524ALA A 546 | None | 1.07A | 2qhfA-1dlcA:0.0 | 2qhfA-1dlcA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dt2 | EXFOLIATIVE TOXIN B (Staphylococcusaureus) |
PF13365(Trypsin_2) | 5 | ALA A 116THR A 62ILE A 104ALA A 70VAL A 42 | None | 1.11A | 2qhfA-1dt2A:0.0 | 2qhfA-1dt2A:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezw | COENZYMEF420-DEPENDENTN5,N10-METHYLENETETRAHYDROMETHANOPTERINREDUCTASE (Methanopyruskandleri) |
PF00296(Bac_luciferase) | 5 | ALA A 26ILE A 328ILE A 23ALA A 34VAL A 324 | None | 1.12A | 2qhfA-1ezwA:0.0 | 2qhfA-1ezwA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fft | UBIQUINOL OXIDASEUBIQUINOL OXIDASE (Escherichiacoli;Escherichiacoli) |
PF00115(COX1)PF00116(COX2)PF06481(COX_ARM) | 5 | ALA B 104THR B 107ILE B 100ALA A 402VAL A 403 | NoneNoneHEO A1002 (-4.4A)NoneNone | 1.09A | 2qhfA-1fftB:undetectable | 2qhfA-1fftB:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gns | SUBTILISIN BPN' (Bacillusamyloliquefaciens) |
PF00082(Peptidase_S8) | 5 | ALA A 230ILE A 175ILE A 234ALA A 273VAL A 198 | None | 1.14A | 2qhfA-1gnsA:0.1 | 2qhfA-1gnsA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ixp | PYRIDOXINE5'-PHOSPHATESYNTHASE (Escherichiacoli) |
PF03740(PdxJ) | 6 | ALA A 222ILE A 218ILE A 13ALA A 30ALA A 34VAL A 231 | None | 1.40A | 2qhfA-1ixpA:undetectable | 2qhfA-1ixpA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jr7 | HYPOTHETICAL 37.4KDA PROTEIN INILEY-GABD INTERGENICREGION (Escherichiacoli) |
PF08943(CsiD) | 5 | ALA A 99ILE A 97MET A 176ALA A 115VAL A 118 | None | 1.02A | 2qhfA-1jr7A:undetectable | 2qhfA-1jr7A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1leh | LEUCINEDEHYDROGENASE (Lysinibacillussphaericus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ALA A 43THR A 112ILE A 126ILE A 83ALA A 27 | None | 0.96A | 2qhfA-1lehA:undetectable | 2qhfA-1lehA:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mx3 | C-TERMINAL BINDINGPROTEIN 1 (Homo sapiens) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | THR A 132ILE A 136ILE A 179ALA A 190ALA A 193 | None | 1.20A | 2qhfA-1mx3A:undetectable | 2qhfA-1mx3A:23.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1q1l | CHORISMATE SYNTHASE (Aquifexaeolicus) |
PF01264(Chorismate_synt) | 8 | ARG A 44ALA A 136THR A 139ILE A 260MET A 320ALA A 352ALA A 356VAL A 359 | None | 0.48A | 2qhfA-1q1lA:40.9 | 2qhfA-1q1lA:44.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1q1l | CHORISMATE SYNTHASE (Aquifexaeolicus) |
PF01264(Chorismate_synt) | 5 | ARG A 44MET A 320ILE A 323ALA A 352ALA A 356 | None | 0.92A | 2qhfA-1q1lA:40.9 | 2qhfA-1q1lA:44.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1r | PUTIDAREDOXINREDUCTASE (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 5 | ALA A 15ILE A 312ALA A 286ALA A 281VAL A 107 | FAD A 749 (-3.3A)NoneNoneNoneNone | 1.14A | 2qhfA-1q1rA:undetectable | 2qhfA-1q1rA:26.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q48 | NIFU-LIKE PROTEIN (Haemophilusinfluenzae) |
PF01592(NifU_N) | 5 | ALA A 85ILE A 73ILE A 45ALA A 117ALA A 113 | None | 0.90A | 2qhfA-1q48A:undetectable | 2qhfA-1q48A:14.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qxo | CHORISMATE SYNTHASE (Streptococcuspneumoniae) |
PF01264(Chorismate_synt) | 9 | ARG A 39ARG A 45ALA A 133THR A 136ILE A 250MET A 310ALA A 342ALA A 346VAL A 349 | EPS A5001 (-2.8A)EPS A5001 ( 2.7A)FMN A4001 ( 3.3A)FMN A4001 ( 4.5A)NoneNoneFMN A4001 (-3.5A)FMN A4001 ( 4.0A)None | 0.47A | 2qhfA-1qxoA:49.5 | 2qhfA-1qxoA:44.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ru3 | ACETYL-COA SYNTHASE (Carboxydothermushydrogenoformans) |
PF03598(CdhC) | 5 | ALA A 606ILE A 604MET A 629ILE A 627VAL A 638 | NoneNoneGOL A 967 (-4.8A)NoneNone | 1.20A | 2qhfA-1ru3A:undetectable | 2qhfA-1ru3A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v93 | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE (Thermusthermophilus) |
PF02219(MTHFR) | 5 | ALA A 172ILE A 134ALA A 127ALA A 105VAL A 144 | NoneNoneFAD A 300 (-3.3A)NoneNone | 1.06A | 2qhfA-1v93A:undetectable | 2qhfA-1v93A:25.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vli | SPORE COATPOLYSACCHARIDEBIOSYNTHESIS PROTEINSPSE (Bacillussubtilis) |
PF03102(NeuB)PF08666(SAF) | 5 | ALA A 21ILE A 38ALA A 44ALA A 42VAL A 103 | None | 1.05A | 2qhfA-1vliA:undetectable | 2qhfA-1vliA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z69 | COENZYMEF420-DEPENDENTN(5),N(10)-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE (Methanosarcinabarkeri) |
PF00296(Bac_luciferase) | 5 | ARG A 243ALA A 186ILE A 298ILE A 175ALA A 177 | None | 1.05A | 2qhfA-1z69A:undetectable | 2qhfA-1z69A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a18 | CARBON DIOXIDECONCENTRATINGMECHANISM PROTEINCCMK HOMOLOG 4 (Synechocystissp. PCC 6803) |
PF00936(BMC) | 5 | ALA A 72THR A 12ILE A 18ALA A 65ALA A 21 | NH4 A 126 (-4.3A)NoneNoneNoneNone | 1.17A | 2qhfA-2a18A:undetectable | 2qhfA-2a18A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2apo | PROBABLE TRNAPSEUDOURIDINESYNTHASE B (Methanocaldococcusjannaschii) |
PF01472(PUA)PF01509(TruB_N)PF08068(DKCLD)PF16198(TruB_C_2) | 5 | ILE A 272ILE A 279ALA A 300ALA A 315VAL A 267 | None | 1.09A | 2qhfA-2apoA:undetectable | 2qhfA-2apoA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpy | FLAGELLUM-SPECIFICATP SYNTHASE (Salmonellaenterica) |
PF00006(ATP-synt_ab) | 5 | ALA A 237MET A 271ILE A 209ALA A 250ALA A 253 | None | 1.12A | 2qhfA-2dpyA:undetectable | 2qhfA-2dpyA:25.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2g85 | CHORISMATE SYNTHASE (Mycobacteriumtuberculosis) |
PF01264(Chorismate_synt) | 7 | ALA A 138THR A 141ILE A 317ARG A 341ALA A 346ALA A 349VAL A 353 | None | 1.31A | 2qhfA-2g85A:59.1 | 2qhfA-2g85A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2g85 | CHORISMATE SYNTHASE (Mycobacteriumtuberculosis) |
PF01264(Chorismate_synt) | 10 | ARG A 40ALA A 138THR A 141ILE A 255MET A 314ILE A 317ARG A 341ALA A 346ALA A 350VAL A 353 | None | 0.48A | 2qhfA-2g85A:59.1 | 2qhfA-2g85A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2g85 | CHORISMATE SYNTHASE (Mycobacteriumtuberculosis) |
PF01264(Chorismate_synt) | 5 | ILE A 258ILE A 317ARG A 341ALA A 346ALA A 350 | None | 0.85A | 2qhfA-2g85A:59.1 | 2qhfA-2g85A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmh | ELECTRON TRANSFERFLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE (Sus scrofa) |
PF05187(ETF_QO)PF13450(NAD_binding_8) | 5 | ALA A 50ILE A 381ILE A 352ALA A 212VAL A 38 | None | 1.09A | 2qhfA-2gmhA:undetectable | 2qhfA-2gmhA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdh | COHESIN (Archaeoglobusfulgidus) |
PF00963(Cohesin) | 5 | ALA A 30THR A 6ILE A 8ILE A 81VAL A 145 | None | 1.11A | 2qhfA-2xdhA:undetectable | 2qhfA-2xdhA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y2w | ARABINOFURANOSIDASE (Bifidobacteriumlongum) |
PF06964(Alpha-L-AF_C) | 5 | ARG A 73ALA A 419ILE A 79ILE A 417ALA A 415 | None | 1.16A | 2qhfA-2y2wA:undetectable | 2qhfA-2y2wA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhg | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF07632(DUF1593) | 5 | ARG A 526ALA A 633ILE A 605ILE A 630ALA A 644 | None | 1.19A | 2qhfA-2yhgA:undetectable | 2qhfA-2yhgA:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c5m | OLIGOGALACTURONATELYASE (Vibrioparahaemolyticus) |
PF14583(Pectate_lyase22) | 5 | THR A 327ILE A 266ILE A 246ALA A 251VAL A 279 | None | 1.20A | 2qhfA-3c5mA:undetectable | 2qhfA-3c5mA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d79 | PUTATIVEUNCHARACTERIZEDPROTEIN PH0734 (Pyrococcushorikoshii) |
PF01472(PUA)PF09183(DUF1947) | 5 | ILE A 111ILE A 118ALA A 140ALA A 155VAL A 106 | None | 1.12A | 2qhfA-3d79A:undetectable | 2qhfA-3d79A:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3a | POSSIBLE PEROXIDASEBPOC (Mycobacteriumtuberculosis) |
PF12697(Abhydrolase_6) | 5 | ALA A 90THR A 112MET A 97ALA A 107VAL A 222 | None | 0.98A | 2qhfA-3e3aA:undetectable | 2qhfA-3e3aA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e49 | UNCHARACTERIZEDPROTEIN DUF849 WITHA TIM BARREL FOLD (Paraburkholderiaxenovorans) |
PF05853(BKACE) | 5 | ALA A 40ILE A 9ILE A 48ALA A 80ALA A 46 | None | 1.02A | 2qhfA-3e49A:undetectable | 2qhfA-3e49A:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ed0 | (3R)-HYDROXYMYRISTOYL-ACYL CARRIERPROTEIN DEHYDRATASE (Helicobacterpylori) |
PF07977(FabA) | 5 | ILE A 104MET A 74ILE A 70ALA A 147ALA A 149 | None | 1.13A | 2qhfA-3ed0A:undetectable | 2qhfA-3ed0A:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3edm | SHORT CHAINDEHYDROGENASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 5 | ALA A 60ILE A 51ALA A 14ALA A 23VAL A 33 | None | 1.13A | 2qhfA-3edmA:undetectable | 2qhfA-3edmA:26.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3en0 | CYANOPHYCINASE (Synechocystissp. PCC 6803) |
PF03575(Peptidase_S51) | 5 | ALA A 205ILE A 169ILE A 199ALA A 135VAL A 166 | None | 1.09A | 2qhfA-3en0A:undetectable | 2qhfA-3en0A:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNITA' (Sulfolobussolfataricus) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | ALA A 506THR A 510ILE A 552ILE A 603ALA A 602 | None | 0.79A | 2qhfA-3hkzA:undetectable | 2qhfA-3hkzA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j09 | COPPER-EXPORTINGP-TYPE ATPASE A (Archaeoglobusfulgidus) |
PF00122(E1-E2_ATPase)PF00403(HMA)PF00702(Hydrolase) | 5 | ILE A 662ILE A 406ALA A 411ALA A 415VAL A 418 | None | 1.00A | 2qhfA-3j09A:undetectable | 2qhfA-3j09A:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j09 | COPPER-EXPORTINGP-TYPE ATPASE A (Archaeoglobusfulgidus) |
PF00122(E1-E2_ATPase)PF00403(HMA)PF00702(Hydrolase) | 5 | ILE A 662ILE A 648ALA A 411ALA A 415VAL A 418 | None | 1.08A | 2qhfA-3j09A:undetectable | 2qhfA-3j09A:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kje | CODEHYDROGENASE/ACETYL-COA SYNTHASECOMPLEX, ACCESSORYPROTEIN COOC (Carboxydothermushydrogenoformans) |
PF01656(CbiA) | 5 | ALA A 178ILE A 143ALA A 6ALA A 4VAL A 154 | None | 1.18A | 2qhfA-3kjeA:undetectable | 2qhfA-3kjeA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3miz | PUTATIVETRANSCRIPTIONALREGULATOR PROTEIN,LACI FAMILY (Rhizobium etli) |
PF13377(Peripla_BP_3) | 5 | ALA A 255ILE A 183ILE A 275ALA A 234VAL A 230 | None | 1.20A | 2qhfA-3mizA:undetectable | 2qhfA-3mizA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6r | PROPIONYL-COACARBOXYLASE, ALPHASUBUNIT (Ruegeriapomeroyi) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ALA A 130THR A 134ILE A 112ALA A 91VAL A 90 | None | 1.00A | 2qhfA-3n6rA:undetectable | 2qhfA-3n6rA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4f | SPERMIDINE SYNTHASE (Escherichiacoli) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 5 | ILE A 62MET A 66ILE A 268ALA A 272ALA A 221 | None | 1.20A | 2qhfA-3o4fA:undetectable | 2qhfA-3o4fA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o63 | PROBABLETHIAMINE-PHOSPHATEPYROPHOSPHORYLASE (Mycobacteriumtuberculosis) |
PF02581(TMP-TENI) | 5 | THR A 15ILE A 39ILE A 66ALA A 25ALA A 28 | None | 1.04A | 2qhfA-3o63A:undetectable | 2qhfA-3o63A:25.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3paj | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE,CARBOXYLATING (Vibrio cholerae) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ALA A 197ILE A 194ALA A 226ALA A 228VAL A 210 | None | 1.04A | 2qhfA-3pajA:undetectable | 2qhfA-3pajA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pyz | BIFUNCTIONALFOLYLPOLYGLUTAMATESYNTHASE/DIHYDROFOLATE SYNTHASE (Yersinia pestis) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | ALA A 273ILE A 70ALA A 69ALA A 296VAL A 265 | None | 1.12A | 2qhfA-3pyzA:undetectable | 2qhfA-3pyzA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3stb | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 5 | ALA A 35ILE A 71ILE A 110ALA A 98VAL A 80 | None | 1.16A | 2qhfA-3stbA:undetectable | 2qhfA-3stbA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t05 | PYRUVATE KINASE (Staphylococcusaureus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 5 | ALA A 377THR A 453ILE A 451ILE A 397VAL A 363 | None | 1.13A | 2qhfA-3t05A:undetectable | 2qhfA-3t05A:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tha | TRYPTOPHAN SYNTHASEALPHA CHAIN (Campylobacterjejuni) |
PF00290(Trp_syntA) | 5 | ALA A 109ILE A 97ILE A 139ALA A 116VAL A 92 | None | 1.09A | 2qhfA-3thaA:undetectable | 2qhfA-3thaA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqv | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Francisellatularensis) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ALA A 188ILE A 185ALA A 217ALA A 219VAL A 201 | None | 1.17A | 2qhfA-3tqvA:undetectable | 2qhfA-3tqvA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u95 | GLYCOSIDE HYDROLASE,FAMILY 4 (Thermotoganeapolitana) |
PF02056(Glyco_hydro_4)PF11975(Glyco_hydro_4C) | 5 | THR A 32ILE A 34ILE A 347ALA A 22VAL A 62 | None | 1.12A | 2qhfA-3u95A:undetectable | 2qhfA-3u95A:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3waj | TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Archaeoglobusfulgidus) |
PF02516(STT3) | 5 | ALA A 120ILE A 164ILE A 144ALA A 433ALA A 167 | None | 1.15A | 2qhfA-3wajA:undetectable | 2qhfA-3wajA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axj | ETHANOLAMINECARBOXYSOMESTRUCTURAL PROTEIN (Clostridioidesdifficile) |
PF00936(BMC) | 5 | ARG A 68ALA A 24ALA A 63ALA A 66VAL A 69 | None | 1.07A | 2qhfA-4axjA:undetectable | 2qhfA-4axjA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cr6 | N-ACYLMANNOSAMINE1-DEHYDROGENASE (Flavobacteriumsp. 141-8) |
PF13561(adh_short_C2) | 5 | ILE A 74MET A 45ILE A 19ALA A 81ALA A 77 | None | 1.11A | 2qhfA-4cr6A:undetectable | 2qhfA-4cr6A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7l | PEPTIDE METHIONINESULFOXIDE REDUCTASEMSRA (Corynebacteriumdiphtheriae) |
PF01625(PMSR) | 5 | THR A 174ILE A 176ILE A 48ALA A 115VAL A 157 | None | 1.15A | 2qhfA-4d7lA:undetectable | 2qhfA-4d7lA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dib | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bacillusanthracis) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | ALA A 95THR A 119ILE A 117ILE A 6VAL A 322 | None | 1.16A | 2qhfA-4dibA:undetectable | 2qhfA-4dibA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e5t | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME, C-TERMINALDOMAIN PROTEIN (Labrenziaalexandrii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 330MET A 287ILE A 312ALA A 302ALA A 298 | None | 1.20A | 2qhfA-4e5tA:undetectable | 2qhfA-4e5tA:24.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ecd | CHORISMATE SYNTHASE (Bifidobacteriumlongum) |
PF01264(Chorismate_synt) | 6 | THR A 140ILE A 255MET A 315ALA A 347ALA A 351VAL A 354 | None | 0.72A | 2qhfA-4ecdA:36.2 | 2qhfA-4ecdA:59.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4h | GLUTAMINE DEPENDENTNAD+ SYNTHETASE (Burkholderiathailandensis) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 5 | ILE A 464MET A 346ALA A 314ALA A 310VAL A 307 | None | 0.96A | 2qhfA-4f4hA:undetectable | 2qhfA-4f4hA:25.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fai | CG5976, ISOFORM B (Drosophilamelanogaster) |
PF04389(Peptidase_M28) | 5 | ALA A 155ILE A 73ILE A 68ALA A 67VAL A 85 | None | 1.01A | 2qhfA-4faiA:undetectable | 2qhfA-4faiA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fx5 | VON WILLEBRANDFACTOR TYPE A (Catenulisporaacidiphila) |
PF13768(VWA_3) | 5 | ARG A 147ALA A 102ILE A 59ALA A 143ALA A 145 | None | 1.15A | 2qhfA-4fx5A:undetectable | 2qhfA-4fx5A:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h4g | (3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE (Burkholderiathailandensis) |
PF07977(FabA) | 5 | ALA A 76ILE A 72ALA A 147ALA A 135VAL A 121 | None | 1.07A | 2qhfA-4h4gA:undetectable | 2qhfA-4h4gA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i83 | 3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN]DEHYDRATASE FABZ (Neisseriameningitidis) |
PF07977(FabA) | 5 | ALA A 70ILE A 66ALA A 140ALA A 128VAL A 114 | None | 1.10A | 2qhfA-4i83A:undetectable | 2qhfA-4i83A:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwa | 4-HYDROXY-3-METHYLBUT-2-EN-1-YLDIPHOSPHATE SYNTHASE (Bacillusanthracis) |
PF04551(GcpE) | 5 | ALA D 66THR D 36ALA D 95ALA D 83VAL D 59 | None | 1.15A | 2qhfA-4mwaD:undetectable | 2qhfA-4mwaD:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nae | HEPTAPRENYLGLYCERYLPHOSPHATE SYNTHASE (Geobacilluskaustophilus) |
PF01884(PcrB) | 5 | THR A 222ILE A 190ALA A 215ALA A 211VAL A 208 | NoneNoneNoneNone1GP A 301 ( 4.6A) | 1.10A | 2qhfA-4naeA:undetectable | 2qhfA-4naeA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oec | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Thermococcuskodakarensis) |
PF03009(GDPD) | 5 | ILE A 38ILE A 8ARG A 4ALA A 35VAL A 31 | None | 1.16A | 2qhfA-4oecA:undetectable | 2qhfA-4oecA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opu | CONSERVED ARCHAEALPROTEIN (Sulfolobusacidocaldarius) |
PF01266(DAO) | 5 | ALA A 20ILE A 315ILE A 286ALA A 156VAL A 8 | None | 1.12A | 2qhfA-4opuA:undetectable | 2qhfA-4opuA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfw | ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN (Thermotogamaritima) |
PF00496(SBP_bac_5) | 5 | ALA A 304ILE A 397MET A 431ALA A 393VAL A 396 | None | 1.06A | 2qhfA-4pfwA:undetectable | 2qhfA-4pfwA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1s | CINNAMOYL COAREDUCTASE (Petunia xhybrida) |
PF01370(Epimerase) | 5 | ILE A 107ILE A 75ALA A 113ALA A 111VAL A 177 | None | 0.95A | 2qhfA-4r1sA:undetectable | 2qhfA-4r1sA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxu | PERIPLASMICSUGAR-BINDINGPROTEIN (Chloroflexusaurantiacus) |
PF13407(Peripla_BP_4) | 5 | ALA A 146THR A 144ILE A 141ALA A 126ALA A 123 | None | 1.12A | 2qhfA-4rxuA:undetectable | 2qhfA-4rxuA:25.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wfs | TRNA-DIHYDROURIDINE(20) SYNTHASE[NAD(P)+]-LIKE (Homo sapiens) |
PF01207(Dus) | 5 | ILE A 140MET A 88ILE A 110ALA A 100ALA A 96 | None | 1.08A | 2qhfA-4wfsA:undetectable | 2qhfA-4wfsA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 5 | ALA A 10ILE A 7ILE A 114ALA A 107ALA A 18 | None | 0.88A | 2qhfA-4x4jA:undetectable | 2qhfA-4x4jA:26.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8f | RIBOKINASE (Vibrio cholerae) |
PF00294(PfkB) | 5 | ALA A 188THR A 192ILE A 219ALA A 202ALA A 206 | None | 0.98A | 2qhfA-4x8fA:undetectable | 2qhfA-4x8fA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9d | PERTUSSIS TOXIN-LIKESUBUNIT ARTA (Escherichiacoli) |
PF02917(Pertussis_S1) | 5 | THR A 53ILE A 82ILE A 87ALA A 84VAL A 7 | None | 1.16A | 2qhfA-4z9dA:undetectable | 2qhfA-4z9dA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zw0 | 3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN]DEHYDRATASE FABZ (CandidatusLiberibacterasiaticus) |
PF07977(FabA) | 5 | ILE A 97MET A 72ILE A 68ALA A 140ALA A 142 | None | 1.19A | 2qhfA-4zw0A:undetectable | 2qhfA-4zw0A:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c05 | PUTATIVEGAMMA-TERPINENESYNTHASE (Thymus vulgaris) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | ARG A 564ILE A 481ILE A 488ALA A 559VAL A 556 | ARG A 564 ( 0.6A)ILE A 481 ( 0.7A)ILE A 488 ( 0.7A)ALA A 559 ( 0.0A)VAL A 556 ( 0.6A) | 1.18A | 2qhfA-5c05A:undetectable | 2qhfA-5c05A:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c54 | DIHYDRODIPICOLINATESYNTHASE/N-ACETYLNEURAMINATE LYASE (Corynebacteriumglutamicum) |
PF00701(DHDPS) | 5 | THR A 107ILE A 140ARG A 60ALA A 53VAL A 144 | None | 1.20A | 2qhfA-5c54A:undetectable | 2qhfA-5c54A:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwc | DESIGNED HELICALREPEAT PROTEIN (syntheticconstruct) |
no annotation | 5 | ALA A 87ILE A 127ILE A 113ALA A 134ALA A 130 | None | 1.11A | 2qhfA-5cwcA:undetectable | 2qhfA-5cwcA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwm | DESIGNED HELICALREPEAT PROTEIN (syntheticconstruct) |
no annotation | 5 | ALA A 97ILE A 137ALA A 146ALA A 150VAL A 153 | None | 0.76A | 2qhfA-5cwmA:undetectable | 2qhfA-5cwmA:24.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dt5 | BETA-GLUCOSIDASE (Exiguobacteriumantarcticum) |
PF00232(Glyco_hydro_1) | 5 | THR A 11ILE A 65ILE A 415ALA A 430VAL A 70 | None | 1.13A | 2qhfA-5dt5A:undetectable | 2qhfA-5dt5A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ee5 | BREFELDINA-INHIBITED GUANINENUCLEOTIDE-EXCHANGEPROTEIN 1 (Homo sapiens) |
PF16213(DCB) | 5 | ALA A 174ILE A 151ILE A 131ALA A 158ALA A 154 | NoneNoneNoneNone CL A 312 (-3.4A) | 1.09A | 2qhfA-5ee5A:undetectable | 2qhfA-5ee5A:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ep0 | PUTATIVE REPRESSORPROTEIN LUXO (Photobacteriumangustum) |
PF00072(Response_reg)PF00158(Sigma54_activat) | 5 | ARG A 277ILE A 168ALA A 182ALA A 180VAL A 279 | None | 1.20A | 2qhfA-5ep0A:undetectable | 2qhfA-5ep0A:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ep1 | PUTATIVE REPRESSORPROTEIN LUXO (Photobacteriumangustum) |
PF00158(Sigma54_activat) | 5 | ARG A 277ILE A 168ALA A 182ALA A 180VAL A 279 | None | 1.18A | 2qhfA-5ep1A:undetectable | 2qhfA-5ep1A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5frt | DIMERIC (2FE-2S)PROTEIN (Azotobactervinelandii) |
PF00111(Fer2) | 5 | ALA A 101THR A 104ILE A 54ILE A 38ALA A 31 | None | 1.02A | 2qhfA-5frtA:undetectable | 2qhfA-5frtA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gk2 | KETOSYNTHASE STLD (Photorhabduslaumondii) |
PF08541(ACP_syn_III_C) | 5 | ALA A 92THR A 151ALA A 67ALA A 71VAL A 74 | None | 1.03A | 2qhfA-5gk2A:undetectable | 2qhfA-5gk2A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gn5 | GLYCEROL KINASE (Trypanosomabrucei) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | THR A 246ILE A 78ILE A 62ALA A 241VAL A 231 | None | 1.20A | 2qhfA-5gn5A:undetectable | 2qhfA-5gn5A:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iwx | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Bacillussubtilis) |
PF02542(YgbB) | 5 | ILE A 95ILE A 155ALA A 52ALA A 48VAL A 45 | None | 1.16A | 2qhfA-5iwxA:undetectable | 2qhfA-5iwxA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k7v | DESIGNED PROTEINHR00C3 (syntheticconstruct) |
no annotation | 5 | ALA A 135ILE A 113ILE A 71ALA A 120ALA A 117 | None | 1.19A | 2qhfA-5k7vA:undetectable | 2qhfA-5k7vA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k7v | DESIGNED PROTEINHR00C3 (syntheticconstruct) |
no annotation | 5 | ALA A 177ILE A 133ILE A 113ALA A 140ALA A 137 | None | 1.19A | 2qhfA-5k7vA:undetectable | 2qhfA-5k7vA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyw | PYRUVATE CARBOXYLASE (Lactococcuslactis) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | THR A 748ILE A 755ILE A 741ALA A 777VAL A 525 | None | 1.12A | 2qhfA-5vywA:undetectable | 2qhfA-5vywA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w5b | HTH-TYPETRANSCRIPTIONALREGULATOR CMR (Mycobacteriumtuberculosis) |
no annotation | 5 | ARG A 35THR A 199ALA A 34ALA A 30VAL A 27 | None | 1.11A | 2qhfA-5w5bA:undetectable | 2qhfA-5w5bA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb0 | FUSION GLYCOPROTEINF0 (Humanmetapneumovirus) |
no annotation | 5 | ALA F 86MET F 270ARG F 129ALA F 125VAL F 118 | None | 1.16A | 2qhfA-5wb0F:undetectable | 2qhfA-5wb0F:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wou | PROTEIN LAP4 (Drosophilamelanogaster) |
no annotation | 5 | ILE A 38ILE A 7ALA A 50ALA A 47VAL A 41 | None | 1.08A | 2qhfA-5wouA:undetectable | 2qhfA-5wouA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x2g | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Campylobacterjejuni) |
no annotation | 5 | THR A 651ILE A 476ILE A 9ALA A 644VAL A 679 | None | 1.17A | 2qhfA-5x2gA:undetectable | 2qhfA-5x2gA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xap | PROTEIN TRANSLOCASESUBUNIT SECD (Deinococcusradiodurans) |
PF02355(SecD_SecF)PF07549(Sec_GG) | 5 | ALA A 693THR A 697ILE A 669ILE A 674ALA A 746 | None | 1.15A | 2qhfA-5xapA:undetectable | 2qhfA-5xapA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfo | PHD FINGER PROTEIN 1 (Homo sapiens) |
PF00628(PHD) | 5 | THR A 281ILE A 277ALA A 308ALA A 255VAL A 258 | None | 1.19A | 2qhfA-5xfoA:undetectable | 2qhfA-5xfoA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c08 | ANTIBODY FAB HEAVYCHAIN (Mus musculus) |
no annotation | 5 | THR A 53ILE A 51ALA A 24ALA A 79VAL A 72 | None | 1.10A | 2qhfA-6c08A:undetectable | 2qhfA-6c08A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6chj | DIACYLGLYCEROLO-ACYLTRANSFERASE (Marinobacterhydrocarbonoclasticus) |
no annotation | 5 | ALA A 271ILE A 378ILE A 329ALA A 291VAL A 376 | None | 1.18A | 2qhfA-6chjA:undetectable | 2qhfA-6chjA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fn1 | HUMAN-MOUSE CHIMERICABCB1 (ABCBHM) (Homo sapiens) |
no annotation | 5 | MET A 38ILE A 185ALA A 357ALA A 361VAL A 364 | None | 0.94A | 2qhfA-6fn1A:undetectable | 2qhfA-6fn1A:undetectable |