SIMILAR PATTERNS OF AMINO ACIDS FOR 2QHF_A_ACTA503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chk CHITOSANASE

(Streptomyces
sp. N174) 		PF01374
(Glyco_hydro_46) 		4 GLN A 175
THR A 172
ARG A 171
ALA A 170
 None
 1.17A 2qhfA-1chkA:
0.0		 2qhfA-1chkA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f2j FRUCTOSE-BISPHOSPHAT
E ALDOLASE,
GLYCOSOMAL

(Trypanosoma
brucei) 		PF00274
(Glycolytic) 		4 GLN A 216
THR A 265
ARG A 268
ALA A 267
 None
 1.14A 2qhfA-1f2jA:
0.0		 2qhfA-1f2jA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7l SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSA

(Bacillus
subtilis) 		PF00535
(Glycos_transf_2) 		4 GLN A 148
THR A 150
ALA A 153
ARG A 247
 None
 1.37A 2qhfA-1h7lA:
0.0		 2qhfA-1h7lA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui) 		PF00141
(peroxidase) 		4 GLN A 239
THR A 240
ARG A 243
ALA A 211
 SO4  A 732 (-4.0A)
None
SO4  A 732 (-3.9A)
None
 1.33A 2qhfA-1itkA:
0.0		 2qhfA-1itkA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p33 PTERIDINE REDUCTASE
1

(Leishmania
tarentolae) 		PF13561
(adh_short_C2) 		4 GLN A 169
THR A 165
ARG A 166
ALA A 167
 None
 1.40A 2qhfA-1p33A:
0.0		 2qhfA-1p33A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uz4 MAN5A

(Cellvibrio
mixtus) 		PF00150
(Cellulase) 		4 GLN A 111
THR A 108
ALA A  54
ARG A  61
 None
 1.40A 2qhfA-1uz4A:
undetectable		 2qhfA-1uz4A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg5 PHOSPHOENOLPYRUVATE-
PROTEIN KINASE

(Caldanaerobacter
subterraneus) 		PF02896
(PEP-utilizers_C) 		4 THR A 372
ARG A 375
ALA A 376
ARG A 379
 None
 1.44A 2qhfA-2bg5A:
undetectable		 2qhfA-2bg5A:
24.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2g85 CHORISMATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF01264
(Chorismate_synt) 		4 GLN A  36
THR A 149
ARG A 152
ALA A 151
 None
 1.35A 2qhfA-2g85A:
59.1		 2qhfA-2g85A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2g85 CHORISMATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF01264
(Chorismate_synt) 		5 GLN A  36
THR A 149
ARG A 152
ALA A 153
ARG A 156
 None
 0.29A 2qhfA-2g85A:
59.1		 2qhfA-2g85A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3h NADP-DEPENDENT
OXIDOREDUCTASE P1

(Arabidopsis
thaliana) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 GLN A  76
THR A  73
ALA A  71
ARG A  57
 None
 1.11A 2qhfA-2j3hA:
0.0		 2qhfA-2j3hA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jvz FAR UPSTREAM
ELEMENT-BINDING
PROTEIN 2

(Homo sapiens) 		PF00013
(KH_1) 		4 GLN A  26
ARG A  30
ALA A  31
ARG A  82
 None
 0.92A 2qhfA-2jvzA:
1.7		 2qhfA-2jvzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvx 4-CHLOROBENZOATE COA
LIGASE

(Alcaligenes sp.
AL3007) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 GLN X   2
ARG X  10
ALA X  11
ARG X  14
 None
 1.18A 2qhfA-2qvxX:
undetectable		 2qhfA-2qvxX:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cex UNCHARACTERIZED
PROTEIN

(Enterococcus
faecalis) 		PF04978
(DUF664) 		4 THR A  10
ARG A  13
ALA A  14
ARG A  17
 None
 0.77A 2qhfA-3cexA:
undetectable		 2qhfA-3cexA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 GLN A 171
THR A 147
ALA A 149
ARG A 471
 None
 1.22A 2qhfA-3cghA:
undetectable		 2qhfA-3cghA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvw RE11660P

(Drosophila
melanogaster) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 THR A 140
ARG A 273
ALA A 272
ARG A  17
 None
 1.36A 2qhfA-3cvwA:
undetectable		 2qhfA-3cvwA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhl PUTATIVE
OXIDOREDUCTASE

(Bacteroides
fragilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 THR A 150
ARG A 241
ALA A 152
ARG A 153
 None
 1.36A 2qhfA-3fhlA:
undetectable		 2qhfA-3fhlA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fwu MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN

(Leishmania
major) 		PF01187
(MIF) 		4 GLN A  21
ARG A  24
ALA A  25
ARG A  28
 None
 1.37A 2qhfA-3fwuA:
undetectable		 2qhfA-3fwuA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g2p PCZA361.24

(Amycolatopsis
orientalis) 		PF13649
(Methyltransf_25) 		4 GLN A 120
THR A  95
ALA A  99
ARG A 102
 None
 1.44A 2qhfA-3g2pA:
undetectable		 2qhfA-3g2pA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2x TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 22

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 GLN A 187
ARG A 172
ALA A 144
ARG A 141
 None
None
None
PO4  A 901 ( 4.9A)
 1.46A 2qhfA-3h2xA:
undetectable		 2qhfA-3h2xA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwk METHYLCITRATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF00285
(Citrate_synt) 		4 THR A 293
ARG A 296
ALA A 297
ARG A 300
 None
 1.12A 2qhfA-3hwkA:
undetectable		 2qhfA-3hwkA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsk CYPBP37 PROTEIN

(Neurospora
crassa) 		PF01946
(Thi4) 		4 THR A  61
ARG A  64
ALA A  65
ARG A  68
 None
 0.69A 2qhfA-3jskA:
undetectable		 2qhfA-3jskA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3knz PUTATIVE SUGAR
BINDING PROTEIN

(Salmonella
enterica) 		PF01380
(SIS) 		4 GLN A  54
THR A  51
ARG A  50
ALA A  49
 None
 1.47A 2qhfA-3knzA:
undetectable		 2qhfA-3knzA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfe SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Legionella
pneumophila) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 GLN A  14
THR A 139
ARG A 142
ALA A 143
 None
 1.40A 2qhfA-3pfeA:
undetectable		 2qhfA-3pfeA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2n SERINE PROTEASE
HEPSIN

(Homo sapiens) 		PF00089
(Trypsin)
PF09272
(Hepsin-SRCR) 		4 THR A 292
ARG A 313
ALA A 312
ARG A 167
 None
 1.27A 2qhfA-3t2nA:
undetectable		 2qhfA-3t2nA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Escherichia
coli;
Archaeoglobus
fulgidus) 		PF13416
(SBP_bac_8) 		4 THR A 508
ARG A 511
ALA A 561
ARG A 563
 None
 1.22A 2qhfA-3waiA:
undetectable		 2qhfA-3waiA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbm DNA/RNA-BINDING
PROTEIN ALBA 1

(Sulfolobus
shibatae) 		PF01918
(Alba) 		4 GLN A  75
THR A  89
ARG A  42
ALA A  41
 None
None
C  X  13 ( 3.9A)
None
 1.04A 2qhfA-3wbmA:
undetectable		 2qhfA-3wbmA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0s DEAMIDASE-DEPUPYLASE
DOP

(Acidothermus
cellulolyticus) 		PF03136
(Pup_ligase) 		4 THR A 432
ARG A 433
ALA A 434
ARG A 437
 None
ATP  A1501 (-3.5A)
None
None
 1.37A 2qhfA-4b0sA:
1.6		 2qhfA-4b0sA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbw SIALIDASE
(NEURAMINIDASE)

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 THR A 398
ARG A 415
ALA A 400
ARG A 422
 None
 1.36A 2qhfA-4bbwA:
undetectable		 2qhfA-4bbwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dqa UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF08522
(DUF1735)
PF13385
(Laminin_G_3) 		4 GLN A 322
THR A 319
ARG A 318
ALA A 317
 None
 1.10A 2qhfA-4dqaA:
undetectable		 2qhfA-4dqaA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdw LEUCINE RICH
HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF07523
(Big_3)
PF13306
(LRR_5) 		4 GLN A 354
THR A 353
ALA A 330
ARG A 331
 None
 1.35A 2qhfA-4fdwA:
undetectable		 2qhfA-4fdwA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj6 GLYCOSIDE HYDROLASE
FAMILY 33, CANDIDATE
SIALIDASE

(Parabacteroides
distasonis) 		PF13859
(BNR_3)
PF14873
(BNR_assoc_N) 		4 THR A 394
ARG A 411
ALA A 396
ARG A 418
 None
PO4  A 607 (-2.7A)
None
None
 1.32A 2qhfA-4fj6A:
undetectable		 2qhfA-4fj6A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4laf NAD(P)H
DEHYDROGENASE
(QUINONE)

(Pseudomonas sp.
WBC-3) 		PF03358
(FMN_red) 		4 GLN A 127
THR A 120
ALA A 173
ARG A 179
 None
FMN  A 400 (-3.8A)
FMN  A 400 ( 4.1A)
None
 1.40A 2qhfA-4lafA:
undetectable		 2qhfA-4lafA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4neo PEPTIDE SYNTHETASE
NRPS TYPE II-PCP

(Streptomyces
verticillus) 		PF00550
(PP-binding) 		4 THR A   9
ARG A  12
ALA A  13
ARG A  16
 None
 0.95A 2qhfA-4neoA:
undetectable		 2qhfA-4neoA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o2i NON-LEE ENCODED TYPE
III EFFECTOR C

(Citrobacter
rodentium) 		PF13678
(Peptidase_M85) 		4 GLN A 178
THR A  79
ALA A  83
ARG A  86
 None
 1.44A 2qhfA-4o2iA:
undetectable		 2qhfA-4o2iA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o99 ACETYL-COA
ACETYLTRANSFERASE

(Cupriavidus
necator) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 GLN A 190
THR A 216
ALA A  13
ARG A  11
 None
 1.40A 2qhfA-4o99A:
undetectable		 2qhfA-4o99A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0s CROSSOVER JUNCTION
ENDONUCLEASE MUS81

(Homo sapiens) 		PF02732
(ERCC4) 		4 GLN A 420
THR A 416
ARG A 417
ALA A 413
 None
 1.40A 2qhfA-4p0sA:
undetectable		 2qhfA-4p0sA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4puc SUSD HOMOLOG

(Bacteroides
uniformis) 		PF12741
(SusD-like) 		4 GLN A 173
THR A 149
ALA A 151
ARG A 462
 None
 1.25A 2qhfA-4pucA:
undetectable		 2qhfA-4pucA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6k BNR/ASP-BOX REPEAT
PROTEIN

(Bacteroides
caccae) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 THR A 414
ARG A 431
ALA A 416
ARG A 438
 None
 1.29A 2qhfA-4q6kA:
undetectable		 2qhfA-4q6kA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN

(Pectobacterium
atrosepticum) 		PF13416
(SBP_bac_8) 		4 GLN A 403
THR A 406
ALA A 193
ARG A 257
 None
 1.49A 2qhfA-4ry1A:
undetectable		 2qhfA-4ry1A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvs VHH DOMAIN BS-1

(Vicugna pacos) 		PF05609
(LAP1C) 		4 THR a 102
ARG a  54
ALA a  34
ARG a  73
 None
 1.24A 2qhfA-4tvsa:
1.6		 2qhfA-4tvsa:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN

([Candida]
glabrata) 		PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central) 		4 GLN A 761
THR A 782
ARG A 781
ALA A 780
 None
 1.10A 2qhfA-5d0fA:
undetectable		 2qhfA-5d0fA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfw SINGLE CHAIN FV
FRAGMENT

(Mus musculus) 		PF07686
(V-set) 		4 GLN H 716
THR H 715
ARG H 551
ALA H 552
 None
 1.41A 2qhfA-5dfwH:
undetectable		 2qhfA-5dfwH:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqn CYTOCHROME P450
CYP125

(Mycolicibacterium
smegmatis) 		PF00067
(p450) 		4 GLN A 300
THR A 302
ARG A 319
ARG A  89
 None
 1.34A 2qhfA-5dqnA:
undetectable		 2qhfA-5dqnA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus scrofa) 		PF00135
(COesterase) 		4 THR A 413
ARG A 416
ALA A 415
ARG A 419
 None
 1.16A 2qhfA-5fv4A:
undetectable		 2qhfA-5fv4A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h80 CARBOXYLASE

(Deinococcus
radiodurans) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 GLN A 247
THR A 251
ARG A 250
ALA A 329
 None
 1.17A 2qhfA-5h80A:
undetectable		 2qhfA-5h80A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5icq METHYLOCYSTIS PARVUS
OBBP MBNE

(Methylocystis
parvus) 		PF00496
(SBP_bac_5) 		4 THR A 552
ARG A 555
ALA A 556
ARG A 559
 None
 0.79A 2qhfA-5icqA:
undetectable		 2qhfA-5icqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lgk IG EPSILON CHAIN C
REGION

(Homo sapiens) 		PF07654
(C1-set) 		4 GLN A 538
THR A 536
ARG A 525
ALA A 526
 None
 1.42A 2qhfA-5lgkA:
undetectable		 2qhfA-5lgkA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tnv AP ENDONUCLEASE,
FAMILY PROTEIN 2

(Mycolicibacterium
smegmatis) 		PF01261
(AP_endonuc_2) 		4 GLN A 130
THR A 127
ALA A 125
ARG A  87
 None
 1.25A 2qhfA-5tnvA:
undetectable		 2qhfA-5tnvA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4z RIBOFLAVIN LYASE

(Herbiconiux) 		no annotation 4 GLN A 343
THR A 342
ARG A 346
ALA A 345
 RBF  A 502 (-4.1A)
9WY  A 501 (-3.7A)
None
None
 1.28A 2qhfA-5w4zA:
undetectable		 2qhfA-5w4zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x0y TRANSCRIPTION
REGULATORY PROTEIN
SNF2

(Saccharomyces
cerevisiae) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		4 GLN O1189
THR O1163
ARG O1164
ALA O1165
 None
 1.35A 2qhfA-5x0yO:
undetectable		 2qhfA-5x0yO:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME COMPLEX
EXONUCLEASE RRP44

(Homo sapiens) 		no annotation 4 THR K 262
ARG K 252
ALA K 253
ARG K 379
 None
 1.35A 2qhfA-6d6qK:
undetectable		 2qhfA-6d6qK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eub ANGIOPOIETIN-RELATED
PROTEIN 4

(Homo sapiens) 		no annotation 4 GLN A 276
THR A 394
ALA A 392
ARG A 278
 None
 1.46A 2qhfA-6eubA:
undetectable		 2qhfA-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fbt LYTIC MUREIN
TRANSGLYCOSYLASE

(Pseudomonas
aeruginosa) 		no annotation 4 GLN A 347
THR A 330
ARG A 331
ALA A 328
 None
 1.14A 2qhfA-6fbtA:
undetectable		 2qhfA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fd2 PUTATIVE APRAMYCIN
BIOSYNTHETIC
OXIDOREDUCTASE 4

(Streptoalloteichus
tenebrarius) 		no annotation 4 THR B  79
ARG B 105
ALA B 104
ARG B 100
 None
 1.08A 2qhfA-6fd2B:
undetectable		 2qhfA-6fd2B:
undetectable