SIMILAR PATTERNS OF AMINO ACIDS FOR 2QHF_A_ACTA502

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bg4 ENDO-1,4-BETA-XYLANA
SE

(Penicillium
simplicissimum) 		PF00331
(Glyco_hydro_10) 		3 GLY A 138
ASP A 137
SER A 183
 None
 0.68A 2qhfA-1bg4A:
0.0		 2qhfA-1bg4A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ddm NUMB PROTEIN

(Drosophila
melanogaster) 		PF00640
(PID) 		3 GLY A 159
ASP A 153
SER A 161
 None
 0.63A 2qhfA-1ddmA:
0.0		 2qhfA-1ddmA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eh5 PALMITOYL PROTEIN
THIOESTERASE 1

(Bos taurus) 		PF02089
(Palm_thioest) 		3 GLY A  40
ASP A  43
SER A  83
 PLM  A 430 ( 3.8A)
None
None
 0.73A 2qhfA-1eh5A:
0.0		 2qhfA-1eh5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5v OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE

(Escherichia
coli) 		PF00881
(Nitroreductase) 		3 GLY A 104
ASP A 107
SER A  46
 None
 0.71A 2qhfA-1f5vA:
0.0		 2qhfA-1f5vA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fu3 DELTA-CONOTOXIN
TXVIA

(Conus textile) 		no annotation 3 GLY A  19
ASP A  18
SER A   5
 None
 0.67A 2qhfA-1fu3A:
undetectable		 2qhfA-1fu3A:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gv3 MANGANESE SUPEROXIDE
DISMUTASE

(Nostoc sp. PCC
7120) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		3 GLY A 158
ASP A 160
SER A 181
 None
 0.72A 2qhfA-1gv3A:
undetectable		 2qhfA-1gv3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)

(Leishmania
mexicana) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 GLY A 213
ASP A 210
SER A 207
 None
 0.59A 2qhfA-1gyqA:
1.4		 2qhfA-1gyqA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h2u 20 KDA NUCLEAR CAP
BINDING PROTEIN

(Homo sapiens) 		PF00076
(RRM_1) 		3 GLY X 118
ASP X 116
SER X  39
 None
7MG  X1154 (-4.0A)
None
 0.46A 2qhfA-1h2uX:
undetectable		 2qhfA-1h2uX:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ile ISOLEUCYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 GLY A 314
ASP A 313
SER A 310
 None
 0.74A 2qhfA-1ileA:
undetectable		 2qhfA-1ileA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrt INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Tritrichomonas
suis) 		PF00478
(IMPDH) 		3 GLY A 265
ASP A 264
SER A 262
 None
TRS  A 600 ( 3.1A)
TAD  A 901 ( 2.6A)
 0.65A 2qhfA-1lrtA:
undetectable		 2qhfA-1lrtA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1c MAJOR COAT PROTEIN

(Saccharomyces
cerevisiae
virus L-A) 		PF09220
(LA-virus_coat) 		3 GLY A 397
ASP A 396
SER A 393
 None
 0.72A 2qhfA-1m1cA:
undetectable		 2qhfA-1m1cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mew INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Tritrichomonas
suis) 		PF00478
(IMPDH)
PF00571
(CBS) 		3 GLY A 265
ASP A 264
SER A 262
 None
K  A 900 (-2.4A)
NAD  A 987 (-2.7A)
 0.61A 2qhfA-1mewA:
undetectable		 2qhfA-1mewA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mfq SIGNAL RECOGNITION
PARTICLE 54KDA
PROTEIN

(Homo sapiens) 		PF02978
(SRP_SPB) 		3 GLY C 392
ASP C 391
SER C 389
 None
 0.74A 2qhfA-1mfqC:
undetectable		 2qhfA-1mfqC:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mjf SPERMIDINE SYNTHASE

(Pyrococcus
furiosus) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		3 GLY A  84
ASP A  85
SER A 113
 None
 0.74A 2qhfA-1mjfA:
undetectable		 2qhfA-1mjfA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5h FORMIMINOTETRAHYDROF
OLATE CYCLODEAMINASE

(Thermotoga
maritima) 		PF04961
(FTCD_C) 		3 GLY A  25
ASP A  80
SER A  29
 None
 0.72A 2qhfA-1o5hA:
1.9		 2qhfA-1o5hA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pja PALMITOYL-PROTEIN
THIOESTERASE 2
PRECURSOR

(Homo sapiens) 		PF02089
(Palm_thioest) 		3 GLY A  44
ASP A  47
SER A  79
 None
 0.73A 2qhfA-1pjaA:
undetectable		 2qhfA-1pjaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb2 HUMAN SIGNAL
RECOGNITION PARTICLE
54 KD PROTEIN

(Homo sapiens) 		PF02978
(SRP_SPB) 		3 GLY A 392
ASP A 391
SER A 389
 None
 0.73A 2qhfA-1qb2A:
undetectable		 2qhfA-1qb2A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qw2 CONSERVED
HYPOTHETICAL PROTEIN
TA1206

(Thermoplasma
acidophilum) 		PF08827
(DUF1805) 		3 GLY A  69
ASP A  70
SER A  93
 None
 0.52A 2qhfA-1qw2A:
undetectable		 2qhfA-1qw2A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sdd COAGULATION FACTOR V

(Bos taurus) 		PF07732
(Cu-oxidase_3) 		3 GLY A  97
ASP A 112
SER A  83
 None
CA  A2184 (-2.5A)
None
 0.72A 2qhfA-1sddA:
undetectable		 2qhfA-1sddA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		3 GLY B 159
ASP B 158
SER B 198
 None
 0.74A 2qhfA-1tnuB:
undetectable		 2qhfA-1tnuB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5f PYRUVATE OXIDASE

(Aerococcus
viridans) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 GLY A 165
ASP A 166
SER A  34
 None
 0.53A 2qhfA-1v5fA:
undetectable		 2qhfA-1v5fA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrq SARCOSINE OXIDASE
ALPHA SUBUNIT

(Corynebacterium
sp. U-96) 		PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF12831
(FAD_oxidored)
PF13510
(Fer2_4) 		3 GLY A 671
ASP A 670
SER A 857
 None
 0.65A 2qhfA-1vrqA:
undetectable		 2qhfA-1vrqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110

(Homo sapiens) 		PF00515
(TPR_1)
PF13181
(TPR_8)
PF13414
(TPR_11)
PF13424
(TPR_12) 		3 GLY A 115
ASP A 114
SER A  83
 None
 0.73A 2qhfA-1w3bA:
undetectable		 2qhfA-1w3bA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w5d PENICILLIN-BINDING
PROTEIN

(Bacillus
subtilis) 		PF02113
(Peptidase_S13) 		3 GLY A  44
ASP A  45
SER A 357
 None
 0.50A 2qhfA-1w5dA:
undetectable		 2qhfA-1w5dA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkb LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 GLY A 194
ASP A 195
SER A  85
 SO4  A 901 ( 4.8A)
SO4  A 906 ( 4.9A)
SO4  A 901 (-2.8A)
 0.62A 2qhfA-1wkbA:
undetectable		 2qhfA-1wkbA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yw5 PEPTIDYL PROLYL
CIS/TRANS ISOMERASE

(Candida
albicans) 		PF00397
(WW)
PF00639
(Rotamase) 		3 GLY A  66
ASP A  65
SER A 140
 None
 0.74A 2qhfA-1yw5A:
undetectable		 2qhfA-1yw5A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zc6 PROBABLE
N-ACETYLGLUCOSAMINE
KINASE

(Chromobacterium
violaceum) 		PF01869
(BcrAD_BadFG) 		3 GLY A 111
ASP A 110
SER A 283
 None
 0.70A 2qhfA-1zc6A:
undetectable		 2qhfA-1zc6A:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ztv HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF01904
(DUF72) 		3 GLY A  17
ASP A  13
SER A  21
 None
 0.67A 2qhfA-1ztvA:
undetectable		 2qhfA-1ztvA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		3 GLY A 329
ASP A 330
SER A 309
 None
 0.52A 2qhfA-2b5mA:
undetectable		 2qhfA-2b5mA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1t ACYL TRANSFERASE

(Chrysanthemum x
morifolium) 		PF02458
(Transferase) 		3 GLY A 100
ASP A 101
SER A  16
 None
 0.64A 2qhfA-2e1tA:
undetectable		 2qhfA-2e1tA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exu TRANSCRIPTION
INITIATION PROTEIN
SPT4/SPT5

(Saccharomyces
cerevisiae) 		PF03439
(Spt5-NGN)
PF06093
(Spt4) 		3 GLY A  80
ASP A  79
SER A  43
 None
 0.70A 2qhfA-2exuA:
undetectable		 2qhfA-2exuA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyv V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A

(Homo sapiens) 		PF00017
(SH2) 		3 GLY A   5
ASP A   6
SER A  12
 None
 0.49A 2qhfA-2eyvA:
undetectable		 2qhfA-2eyvA:
17.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2g85 CHORISMATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF01264
(Chorismate_synt) 		3 GLY A 240
ASP A 241
SER A 246
 None
 0.32A 2qhfA-2g85A:
26.3		 2qhfA-2g85A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9b CALBINDIN

(Rattus
norvegicus) 		PF13405
(EF-hand_6)
PF13499
(EF-hand_7) 		3 GLY A 259
ASP A 260
SER A 257
 None
 0.74A 2qhfA-2g9bA:
undetectable		 2qhfA-2g9bA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT

(Stenotrophomonas
maltophilia) 		PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4) 		3 GLY A 672
ASP A 671
SER A 858
 None
 0.61A 2qhfA-2gahA:
undetectable		 2qhfA-2gahA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2go7 HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Streptococcus
pneumoniae) 		PF13419
(HAD_2) 		3 GLY A 163
ASP A 168
SER A 179
 None
MG  A 207 ( 4.5A)
None
 0.73A 2qhfA-2go7A:
undetectable		 2qhfA-2go7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwg 4-OXALOMESACONATE
HYDRATASE

(Rhodopseudomonas
palustris) 		PF04909
(Amidohydro_2) 		3 GLY A  80
ASP A  81
SER A 116
 None
 0.53A 2qhfA-2gwgA:
undetectable		 2qhfA-2gwgA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hh9 THIAMIN
PYROPHOSPHOKINASE

(Candida
albicans) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		3 GLY A 112
ASP A 142
SER A 146
 MG  A 804 ( 4.9A)
MG  A 802 ( 2.4A)
None
 0.68A 2qhfA-2hh9A:
undetectable		 2qhfA-2hh9A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2out MU-LIKE PROPHAGE
FLUMU PROTEIN GP35,
PROTEIN HI1507 IN
MU-LIKE PROPHAGE
FLUMU REGION

(Haemophilus
influenzae) 		PF12949
(HeH) 		3 GLY A 126
ASP A 125
SER A 129
 None
 0.69A 2qhfA-2outA:
undetectable		 2qhfA-2outA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE

(Medicago
truncatula) 		PF00201
(UDPGT) 		3 GLY A  74
ASP A  73
SER A  94
 None
 0.67A 2qhfA-2pq6A:
undetectable		 2qhfA-2pq6A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvs PANCREATIC
LIPASE-RELATED
PROTEIN 2

(Homo sapiens) 		PF00151
(Lipase)
PF01477
(PLAT) 		3 GLY A  76
ASP A  79
SER A 110
 None
 0.68A 2qhfA-2pvsA:
undetectable		 2qhfA-2pvsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3v MEVALONATE KINASE

(Homo sapiens) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		3 GLY A 171
ASP A 172
SER A 381
 None
 0.73A 2qhfA-2r3vA:
undetectable		 2qhfA-2r3vA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR

(Bacteroides
fragilis) 		PF05406
(WGR) 		3 GLY A 188
ASP A 212
SER A 216
 None
 0.58A 2qhfA-2ra8A:
undetectable		 2qhfA-2ra8A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsc PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF02605
(PsaL) 		3 GLY L 135
ASP L 134
SER L 132
 None
 0.72A 2qhfA-2wscL:
undetectable		 2qhfA-2wscL:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLY A  19
ASP A  18
SER A 183
 None
 0.69A 2qhfA-2xybA:
undetectable		 2qhfA-2xybA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyo SPRY
DOMAIN-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF00622
(SPRY) 		3 GLY A 143
ASP A 142
SER A 140
 None
 0.74A 2qhfA-2yyoA:
undetectable		 2qhfA-2yyoA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc0 ALANINE GLYOXYLATE
TRANSAMINASE

(Thermococcus
litoralis) 		PF00155
(Aminotran_1_2) 		3 GLY A  42
ASP A  43
SER A 383
 None
 0.55A 2qhfA-2zc0A:
undetectable		 2qhfA-2zc0A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsu SPERMIDINE SYNTHASE

(Pyrococcus
horikoshii) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		3 GLY A  86
ASP A  87
SER A 116
 None
AG3  A1001 (-3.0A)
None
 0.70A 2qhfA-2zsuA:
undetectable		 2qhfA-2zsuA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyl POSSIBLE
OXIDOREDUCTASE

(Mycobacterium
tuberculosis) 		PF00355
(Rieske) 		3 GLY A  95
ASP A  96
SER A 116
 None
 0.50A 2qhfA-2zylA:
undetectable		 2qhfA-2zylA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9s D-ARABINOSE
ISOMERASE

(Aeribacillus
pallidus) 		PF02952
(Fucose_iso_C)
PF07881
(Fucose_iso_N1)
PF07882
(Fucose_iso_N2) 		3 GLY A 449
ASP A 264
SER A 268
 None
 0.70A 2qhfA-3a9sA:
undetectable		 2qhfA-3a9sA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3azq AMINOPEPTIDASE

(Streptomyces
morookaense) 		PF00326
(Peptidase_S9) 		3 GLY A  33
ASP A  34
SER A 345
 None
 0.69A 2qhfA-3azqA:
undetectable		 2qhfA-3azqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be5 PUTATIVE IRON
COMPOUND-BINDING
PROTEIN OF ABC
TRANSPORTER FAMILY

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		3 GLY A  65
ASP A  46
SER A  63
 None
 0.62A 2qhfA-3be5A:
undetectable		 2qhfA-3be5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf0 PROTEASE 4

(Escherichia
coli) 		PF01343
(Peptidase_S49) 		3 GLY A 527
ASP A 531
SER A 525
 None
 0.73A 2qhfA-3bf0A:
undetectable		 2qhfA-3bf0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5z PUTATIVE
GLUCONOLACTONASE

(Deinococcus
radiodurans) 		PF08450
(SGL) 		3 GLY A 176
ASP A 119
SER A 131
 None
 0.70A 2qhfA-3e5zA:
undetectable		 2qhfA-3e5zA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e6a GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
CYTOSOLIC

(Oryza sativa) 		no annotation 3 GLY O 200
ASP O 197
SER O 194
 None
 0.59A 2qhfA-3e6aO:
undetectable		 2qhfA-3e6aO:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 BETA
CHAIN

(Escherichia
coli) 		PF13247
(Fer4_11)
PF14711
(Nitr_red_bet_C) 		3 GLY B 483
ASP B 482
SER B 496
 None
 0.64A 2qhfA-3egwB:
undetectable		 2qhfA-3egwB:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f75 CATHEPSIN L PROTEASE

(Toxoplasma
gondii) 		PF00112
(Peptidase_C1) 		3 GLY A  67
ASP A  78
SER A  63
 None
 0.70A 2qhfA-3f75A:
undetectable		 2qhfA-3f75A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Shewanella
oneidensis) 		PF08240
(ADH_N) 		3 GLY A  65
ASP A  64
SER A  96
 None
 0.64A 2qhfA-3gohA:
undetectable		 2qhfA-3gohA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3juu PORPHYRANASE B

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		3 GLY A 164
ASP A 177
SER A 162
 None
 0.60A 2qhfA-3juuA:
undetectable		 2qhfA-3juuA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kiz PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE

(Cytophaga
hutchinsonii) 		PF02769
(AIRS_C) 		3 GLY A  57
ASP A  56
SER A 162
 None
EDO  A 398 (-2.8A)
None
 0.59A 2qhfA-3kizA:
undetectable		 2qhfA-3kizA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE

(Parabacteroides
distasonis) 		PF02769
(AIRS_C) 		3 GLY A  56
ASP A  55
SER A 161
 None
CA  A 390 ( 3.0A)
None
 0.59A 2qhfA-3mdoA:
undetectable		 2qhfA-3mdoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwt NUCLEOPROTEIN

(Lassa
mammarenavirus) 		PF00843
(Arena_nucleocap)
PF17290
(Arena_ncap_C) 		3 GLY A 316
ASP A 315
SER A 313
 None
 0.63A 2qhfA-3mwtA:
undetectable		 2qhfA-3mwtA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n23 SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		3 GLY A 709
ASP A 714
SER A 718
 PHD  A 369 ( 3.5A)
PHD  A 369 ( 2.9A)
None
 0.71A 2qhfA-3n23A:
undetectable		 2qhfA-3n23A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE

(Bacteroides
ovatus) 		no annotation 3 GLY A 135
ASP A 136
SER A 107
 None
 0.67A 2qhfA-3n6zA:
undetectable		 2qhfA-3n6zA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		3 GLY B 599
ASP B 864
SER B 603
 None
 0.65A 2qhfA-3o8oB:
undetectable		 2qhfA-3o8oB:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oox PUTATIVE 2OG-FE(II)
OXYGENASE FAMILY
PROTEIN

(Caulobacter
vibrioides) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		3 GLY A 191
ASP A 192
SER A 244
 None
 0.46A 2qhfA-3ooxA:
undetectable		 2qhfA-3ooxA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		3 GLY A 165
ASP A 166
SER A 159
 None
 0.75A 2qhfA-3opyA:
undetectable		 2qhfA-3opyA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		3 GLY B 584
ASP B 849
SER B 588
 None
 0.56A 2qhfA-3opyB:
undetectable		 2qhfA-3opyB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppu GLUTATHIONE-S-TRANSF
ERASE

(Phanerochaete
chrysosporium) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		3 GLY A 154
ASP A 153
SER A  41
 None
 0.65A 2qhfA-3ppuA:
undetectable		 2qhfA-3ppuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qc2 GLYCOSYL HYDROLASE

(Bacteroides
ovatus) 		PF04041
(Glyco_hydro_130) 		3 GLY A 263
ASP A 297
SER A 267
 None
 0.62A 2qhfA-3qc2A:
undetectable		 2qhfA-3qc2A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r67 PUTATIVE GLYCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF04041
(Glyco_hydro_130) 		3 GLY A 260
ASP A 295
SER A 264
 None
 0.65A 2qhfA-3r67A:
undetectable		 2qhfA-3r67A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7s CASPASE-2 SUBUNIT
P18

(Homo sapiens) 		PF00656
(Peptidase_C14) 		3 GLY A 222
ASP A 225
SER A 206
 None
 0.61A 2qhfA-3r7sA:
undetectable		 2qhfA-3r7sA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slk POLYKETIDE SYNTHASE
EXTENDER MODULE 2

(Saccharopolyspora
spinosa) 		PF08240
(ADH_N)
PF08659
(KR)
PF13602
(ADH_zinc_N_2) 		3 GLY A 202
ASP A 201
SER A 199
 None
 0.68A 2qhfA-3slkA:
undetectable		 2qhfA-3slkA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5q NUCLEOPROTEIN

(Mopeia Lassa
virus
reassortant 29) 		PF00843
(Arena_nucleocap) 		3 GLY A 316
ASP A 315
SER A 313
 None
 0.67A 2qhfA-3t5qA:
undetectable		 2qhfA-3t5qA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6c PUTATIVE MAND FAMILY
DEHYDRATASE

(Pantoea
ananatis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLY A 130
ASP A 129
SER A 139
 None
 0.72A 2qhfA-3t6cA:
undetectable		 2qhfA-3t6cA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6s CERJ

(Streptomyces
tendae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		3 GLY A 178
ASP A 177
SER A 174
 None
 0.54A 2qhfA-3t6sA:
undetectable		 2qhfA-3t6sA:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE

(Parabacteroides
distasonis) 		PF04041
(Glyco_hydro_130) 		3 GLY A 268
ASP A 303
SER A 272
 None
EDO  A 400 (-3.5A)
None
 0.66A 2qhfA-3tawA:
undetectable		 2qhfA-3tawA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tj0 NUCLEOPROTEIN

(Influenza B
virus) 		PF00506
(Flu_NP) 		3 GLY A 457
ASP A 456
SER A 477
 None
 0.55A 2qhfA-3tj0A:
undetectable		 2qhfA-3tj0A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3voq TARGET OF RAPAMYCIN
COMPLEX 2 SUBUNIT
MAPKAP1

(Homo sapiens) 		PF16979
(SIN1_PH) 		3 GLY A 406
ASP A 407
SER A 434
 None
 0.74A 2qhfA-3voqA:
undetectable		 2qhfA-3voqA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a7l MYOSIN IE HEAVY
CHAIN

(Dictyostelium
discoideum) 		PF00063
(Myosin_head) 		3 GLY C 529
ASP C 530
SER C 533
 None
 0.68A 2qhfA-4a7lC:
undetectable		 2qhfA-4a7lC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ars HISTIDINE ACID
PHOSPHATASE

(Hafnia alvei) 		PF00328
(His_Phos_2) 		3 GLY A 205
ASP A 204
SER A 136
 None
 0.74A 2qhfA-4arsA:
undetectable		 2qhfA-4arsA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aud MAJOR ALLERGEN ALT A
1 SUBUNIT

(Alternaria
alternata) 		PF16541
(AltA1) 		3 GLY A  73
ASP A  56
SER A  71
 SO4  A1130 (-3.3A)
None
None
 0.69A 2qhfA-4audA:
undetectable		 2qhfA-4audA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
GAMMA

(Methanothermobacter
marburgensis) 		PF00037
(Fer4)
PF01058
(Oxidored_q6) 		3 GLY B  59
ASP B  60
SER B  63
 SF4  B1274 (-3.5A)
SF4  B1274 (-1.7A)
None
 0.74A 2qhfA-4ci0B:
undetectable		 2qhfA-4ci0B:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csu GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		3 GLY 9  36
ASP 9  35
SER 9  22
 U  B2555 ( 4.5A)
G  B2553 ( 2.7A)
None
 0.64A 2qhfA-4csu9:
undetectable		 2qhfA-4csu9:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvc ALCOHOL
DEHYDROGENASE

(Pseudogluconobacter
saccharoketogenes) 		PF13360
(PQQ_2) 		3 GLY A 360
ASP A 409
SER A 358
 None
 0.72A 2qhfA-4cvcA:
undetectable		 2qhfA-4cvcA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvc ALCOHOL
DEHYDROGENASE

(Pseudogluconobacter
saccharoketogenes) 		PF13360
(PQQ_2) 		3 GLY A 411
ASP A 408
SER A 358
 None
 0.74A 2qhfA-4cvcA:
undetectable		 2qhfA-4cvcA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dnv AT5G63860/MGI19_6

(Arabidopsis
thaliana) 		PF00415
(RCC1) 		3 GLY A 355
ASP A 367
SER A 365
 None
 0.69A 2qhfA-4dnvA:
undetectable		 2qhfA-4dnvA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4etp KINESIN-LIKE PROTEIN
KAR3

(Saccharomyces
cerevisiae) 		PF00225
(Kinesin) 		3 GLY A 488
ASP A 489
SER A 494
 None
 0.67A 2qhfA-4etpA:
undetectable		 2qhfA-4etpA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f1h TYROSYL-DNA
PHOSPHODIESTERASE 2

(Danio rerio) 		PF03372
(Exo_endo_phos) 		3 GLY A 186
ASP A 185
SER A 183
 None
 0.48A 2qhfA-4f1hA:
undetectable		 2qhfA-4f1hA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd6 ARYLALKYLAMINE
N-ACETYLTRANSFERASE
2

(Aedes aegypti) 		PF00583
(Acetyltransf_1) 		3 GLY A  82
ASP A  62
SER A  65
 None
 0.74A 2qhfA-4fd6A:
undetectable		 2qhfA-4fd6A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hrs SMALL ARCHAEAL
MODIFIER PROTEIN 2

(Haloferax
volcanii) 		no annotation 3 GLY A  21
ASP A  20
SER A  51
 None
 0.74A 2qhfA-4hrsA:
undetectable		 2qhfA-4hrsA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A

(Mus musculus) 		PF13516
(LRR_6) 		3 GLY A 321
ASP A 290
SER A 294
 None
 0.71A 2qhfA-4k17A:
undetectable		 2qhfA-4k17A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l0o CYSTATHIONINE
GAMMA-SYNTHASE

(Helicobacter
pylori) 		no annotation 3 GLY H  88
ASP H  89
SER H 115
 None
 0.68A 2qhfA-4l0oH:
undetectable		 2qhfA-4l0oH:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4miv N-SULPHOGLUCOSAMINE
SULPHOHYDROLASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 GLY A 275
ASP A  32
SER A 272
 None
FGP  A  70 (-3.0A)
None
 0.70A 2qhfA-4mivA:
undetectable		 2qhfA-4mivA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mmh HEPARINASE III
PROTEIN

(Pedobacter
heparinus) 		PF07940
(Hepar_II_III)
PF16889
(Hepar_II_III_N) 		3 GLY A 347
ASP A 348
SER A 291
 CA  A 702 ( 4.6A)
None
None
 0.69A 2qhfA-4mmhA:
undetectable		 2qhfA-4mmhA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onz PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
ovatus) 		PF04041
(Glyco_hydro_130) 		3 GLY A 261
ASP A 295
SER A 265
 None
 0.64A 2qhfA-4onzA:
undetectable		 2qhfA-4onzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p08 COCAINE ESTERASE

(Rhodococcus sp.
MB1) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		3 GLY A 411
ASP A 412
SER A 286
 None
 0.54A 2qhfA-4p08A:
undetectable		 2qhfA-4p08A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p46 J809.B5 TCR Y31A
ALPHA CHAIN (VA2.8)

(Mus musculus) 		PF07686
(V-set)
PF09291
(DUF1968) 		3 GLY A  95
ASP A  97
SER A  93
 None
 0.68A 2qhfA-4p46A:
undetectable		 2qhfA-4p46A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p56 PUTATIVE
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		3 GLY A 111
ASP A 112
SER A 116
 None
 0.62A 2qhfA-4p56A:
undetectable		 2qhfA-4p56A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE SUBUNIT D

(Thermococcus
kodakarensis) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		3 GLY D 109
ASP D 108
SER D 106
 None
 0.59A 2qhfA-4qiwD:
undetectable		 2qhfA-4qiwD:
21.41