SIMILAR PATTERNS OF AMINO ACIDS FOR 2QEU_B_ACTB141

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cbg CYANOGENIC
BETA-GLUCOSIDASE


(Trifolium
repens)
PF00232
(Glyco_hydro_1)
3 PRO A 406
ASN A 404
ARG A 461
None
1.01A 2qeuB-1cbgA:
0.7
2qeuB-1cbgA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cr5 SEC18P (RESIDUES 22
- 210)


(Saccharomyces
cerevisiae)
PF02359
(CDC48_N)
PF02933
(CDC48_2)
3 PRO A  35
ASN A  33
ARG A  86
NEN  A 601 (-3.8A)
None
None
0.91A 2qeuB-1cr5A:
undetectable
2qeuB-1cr5A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)


(Homo sapiens;
Homo sapiens)
PF01423
(LSM)
PF01423
(LSM)
3 PRO A   6
ASN B  39
ARG B  73
None
0.93A 2qeuB-1d3bA:
undetectable
2qeuB-1d3bA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ehi D-ALANINE:D-LACTATE
LIGASE


(Leuconostoc
mesenteroides)
PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C)
3 PRO A 317
ASN A 318
ARG A 301
None
MG  A 783 ( 3.3A)
PHY  A 782 (-3.0A)
0.97A 2qeuB-1ehiA:
undetectable
2qeuB-1ehiA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f56 PLANTACYANIN

(Spinacia
oleracea)
PF02298
(Cu_bind_like)
3 PRO A  50
ASN A  40
ARG A  42
None
0.98A 2qeuB-1f56A:
undetectable
2qeuB-1f56A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g6m SHORT NEUROTOXIN 1

(Naja kaouthia)
PF00087
(Toxin_TOLIP)
3 PRO A  12
ASN A  62
ARG A  59
None
0.93A 2qeuB-1g6mA:
undetectable
2qeuB-1g6mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq0 ARGINYL-TRNA
SYNTHETASE


(Thermus
thermophilus)
PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1)
3 PRO A 587
ASN A 231
ARG A 134
None
0.96A 2qeuB-1iq0A:
0.3
2qeuB-1iq0A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lox 15-LIPOXYGENASE

(Oryctolagus
cuniculus)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A 648
ASN A 642
ARG A 641
None
1.03A 2qeuB-1loxA:
0.0
2qeuB-1loxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m6y S-ADENOSYL-METHYLTRA
NSFERASE MRAW


(Thermotoga
maritima)
PF01795
(Methyltransf_5)
3 PRO A 125
ASN A 115
ARG A 122
None
0.71A 2qeuB-1m6yA:
undetectable
2qeuB-1m6yA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nmb N9 NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
3 PRO N 326
ASN N 347
ARG N 292
None
1.07A 2qeuB-1nmbN:
undetectable
2qeuB-1nmbN:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN


(Wolinella
succinogenes;
Wolinella
succinogenes)
PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
PF13085
(Fer2_3)
PF13183
(Fer4_8)
3 PRO B  49
ASN A 508
ARG A 510
None
1.06A 2qeuB-1qlbB:
undetectable
2qeuB-1qlbB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A 834
ASN A 819
ARG A 827
None
0.90A 2qeuB-1rrhA:
0.0
2qeuB-1rrhA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sjp 60 KDA CHAPERONIN 2

(Mycobacterium
tuberculosis)
PF00118
(Cpn60_TCP1)
3 PRO A 492
ASN A 399
ARG A 398
None
1.08A 2qeuB-1sjpA:
2.6
2qeuB-1sjpA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6c ALKALINE SERINE
PROTEASE


(Pseudoalteromonas
sp. AS-11)
PF00082
(Peptidase_S8)
PF02225
(PA)
3 PRO A 332
ASN A 356
ARG A 215
None
1.10A 2qeuB-1v6cA:
undetectable
2qeuB-1v6cA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xog NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
3 PRO A 328
ASN A 348
ARG A 294
None
None
ABW  A1000 (-3.4A)
1.06A 2qeuB-1xogA:
undetectable
2qeuB-1xogA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmb FOLIC ACID SYNTHESIS
PROTEIN FOL1


(Saccharomyces
cerevisiae)
PF00809
(Pterin_bind)
PF01288
(HPPK)
3 PRO A 476
ASN A 712
ARG A 796
None
1.08A 2qeuB-2bmbA:
2.7
2qeuB-2bmbA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dy3 ALANINE RACEMASE

(Corynebacterium
glutamicum)
PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N)
3 PRO A 352
ASN A  39
ARG A 358
None
0.91A 2qeuB-2dy3A:
undetectable
2qeuB-2dy3A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou PERTACTIN
EXTRACELLULAR DOMAIN


(Bordetella
bronchiseptica)
PF03212
(Pertactin)
3 PRO G 463
ASN G 486
ARG G 512
None
0.93A 2qeuB-2iouG:
undetectable
2qeuB-2iouG:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A 830
ASN A 815
ARG A 823
None
1.04A 2qeuB-2iujA:
undetectable
2qeuB-2iujA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuk SEED LIPOXYGENASE

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A 841
ASN A 826
ARG A 834
None
0.73A 2qeuB-2iukA:
undetectable
2qeuB-2iukA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyo 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING


(Lactococcus
lactis)
PF00393
(6PGD)
PF03446
(NAD_binding_2)
3 PRO A 138
ASN A  21
ARG A  25
None
0.94A 2qeuB-2iyoA:
undetectable
2qeuB-2iyoA:
15.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qeu PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE


(Paraburkholderia
xenovorans)
PF02627
(CMD)
3 PRO A  28
ASN A  86
ARG A  89
ACT  A 145 (-3.8A)
ACT  A 145 (-3.1A)
ACT  A 145 ( 4.7A)
0.23A 2qeuB-2qeuA:
25.1
2qeuB-2qeuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8a LONG-CHAIN FATTY
ACID TRANSPORT
PROTEIN


(Escherichia
coli)
PF03349
(Toluene_X)
3 PRO A  34
ASN A 210
ARG A 228
None
0.77A 2qeuB-2r8aA:
undetectable
2qeuB-2r8aA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzx HEPATOCYTE GROWTH
FACTOR RECEPTOR


(Homo sapiens)
PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG)
3 PRO B 534
ASN B 594
ARG B 591
None
1.04A 2qeuB-2uzxB:
undetectable
2qeuB-2uzxB:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vn8 RETICULON-4-INTERACT
ING PROTEIN 1


(Homo sapiens)
PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2)
3 PRO A 376
ASN A  54
ARG A  91
None
1.09A 2qeuB-2vn8A:
undetectable
2qeuB-2vn8A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w92 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D


(Streptococcus
pneumoniae)
PF03644
(Glyco_hydro_85)
3 PRO A 707
ASN A 788
ARG A 622
None
1.02A 2qeuB-2w92A:
undetectable
2qeuB-2w92A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE


(Homo sapiens)
PF03152
(UFD1)
3 PRO A  61
ASN A 113
ARG A  15
None
0.90A 2qeuB-2yujA:
undetectable
2qeuB-2yujA:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5


(Nostoc sp. PCC
7120;
Nostoc sp. PCC
7120)
PF00033
(Cytochrome_B)
PF02529
(PetG)
3 PRO A  28
ASN G  33
ARG G  31
None
0.97A 2qeuB-2zt9A:
undetectable
2qeuB-2zt9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyg 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING


(Klebsiella
pneumoniae)
PF00393
(6PGD)
PF03446
(NAD_binding_2)
3 PRO A 138
ASN A  21
ARG A  25
None
1.09A 2qeuB-2zygA:
undetectable
2qeuB-2zygA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3any ETHANOLAMINE
AMMONIA-LYASE HEAVY
CHAIN


(Escherichia
coli)
PF06751
(EutB)
3 PRO A 194
ASN A 201
ARG A 204
B12  B 601 (-4.9A)
None
None
0.98A 2qeuB-3anyA:
undetectable
2qeuB-3anyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3l ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE


(Homo sapiens)
PF00305
(Lipoxygenase)
3 PRO A 648
ASN A 642
ARG A 641
None
1.05A 2qeuB-3d3lA:
undetectable
2qeuB-3d3lA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ef1 RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE


(Schizosaccharomyces
pombe)
PF03031
(NIF)
PF12738
(PTCB-BRCT)
3 PRO A 211
ASN A 402
ARG A 271
None
0.98A 2qeuB-3ef1A:
undetectable
2qeuB-3ef1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg4 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN


(Plexaura
homomalla)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A1051
ASN A1045
ARG A1044
None
None
GOL  A2306 ( 4.3A)
1.01A 2qeuB-3fg4A:
undetectable
2qeuB-3fg4A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnr OS03G0212800 PROTEIN

(Oryza sativa)
PF00232
(Glyco_hydro_1)
3 PRO A 403
ASN A 401
ARG A 459
PRO  A 403 (-1.1A)
ASN  A 401 ( 0.6A)
ARG  A 459 ( 0.6A)
1.05A 2qeuB-3gnrA:
1.8
2qeuB-3gnrA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jc7 DNA REPLICATION
COMPLEX GINS PROTEIN
PSF2


(Saccharomyces
cerevisiae)
PF05916
(Sld5)
3 PRO B  13
ASN B 179
ARG B 182
None
1.07A 2qeuB-3jc7B:
2.3
2qeuB-3jc7B:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l91 ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ
SUBUNIT BETA


(Pseudomonas
aeruginosa)
PF01804
(Penicil_amidase)
3 PRO B 401
ASN B 371
ARG B 373
OCA  B   1 ( 4.7A)
None
EDO  B 911 (-4.1A)
0.94A 2qeuB-3l91B:
undetectable
2qeuB-3l91B:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om5 LEVANSUCRASE

(Bacillus
megaterium)
PF02435
(Glyco_hydro_68)
3 PRO A 298
ASN A 297
ARG A 290
None
1.07A 2qeuB-3om5A:
undetectable
2qeuB-3om5A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p5p TAXADIENE SYNTHASE

(Taxus
brevifolia)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
3 PRO A 507
ASN A 826
ARG A 828
None
EDO  A 921 (-3.3A)
None
0.82A 2qeuB-3p5pA:
2.5
2qeuB-3p5pA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE


(Sus scrofa)
PF00305
(Lipoxygenase)
3 PRO A 648
ASN A 642
ARG A 641
None
0.94A 2qeuB-3rdeA:
undetectable
2qeuB-3rdeA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9j MEMBER OF DUF4221
FAMILY


(Bacteroides
vulgatus)
PF13970
(DUF4221)
3 PRO A 324
ASN A 287
ARG A 291
None
0.95A 2qeuB-3s9jA:
undetectable
2qeuB-3s9jA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqi KLLA0E03807P

(Kluyveromyces
lactis)
PF16787
(NDC10_II)
3 PRO A 198
ASN A 148
ARG A 312
None
1.00A 2qeuB-3sqiA:
2.2
2qeuB-3sqiA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syj ADHESION AND
PENETRATION PROTEIN
AUTOTRANSPORTER


(Haemophilus
influenzae)
PF02395
(Peptidase_S6)
PF03212
(Pertactin)
3 PRO A 724
ASN A 669
ARG A 668
None
0.67A 2qeuB-3syjA:
undetectable
2qeuB-3syjA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tnq CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-BETA REGULATORY
SUBUNIT


(Mus musculus)
PF00027
(cNMP_binding)
3 PRO A 229
ASN A 227
ARG A 247
None
0.85A 2qeuB-3tnqA:
undetectable
2qeuB-3tnqA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umg HALOACID
DEHALOGENASE


(Rhodococcus
jostii)
PF00702
(Hydrolase)
3 PRO A   5
ASN A  14
ARG A   7
None
0.83A 2qeuB-3umgA:
undetectable
2qeuB-3umgA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v98 ARACHIDONATE
5-LIPOXYGENASE


(Homo sapiens)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A 658
ASN A 652
ARG A 651
None
0.98A 2qeuB-3v98A:
undetectable
2qeuB-3v98A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vf1 11R-LIPOXYGENASE

(Gersemia
fruticosa)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
3 PRO A 664
ASN A 658
ARG A 657
None
0.93A 2qeuB-3vf1A:
undetectable
2qeuB-3vf1A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E


(Streptomyces
chartreusis)
PF01370
(Epimerase)
3 PRO A 199
ASN A 191
ARG A 195
UD1  A 400 (-4.1A)
None
None
1.09A 2qeuB-3vpsA:
undetectable
2qeuB-3vpsA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsj 2-AMINO-5-CHLOROPHEN
OL 1,6-DIOXYGENASE
ALPHA SUBUNIT
2-AMINO-5-CHLOROPHEN
OL 1,6-DIOXYGENASE
BETA SUBUNIT


(Comamonas
testosteroni;
Comamonas
testosteroni)
PF02900
(LigB)
PF02900
(LigB)
3 PRO B 205
ASN B  88
ARG A 108
None
1.04A 2qeuB-3vsjB:
undetectable
2qeuB-3vsjB:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsk PENICILLIN-BINDING
PROTEIN 3


(Staphylococcus
aureus)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
3 PRO A  68
ASN A  83
ARG A 230
None
0.99A 2qeuB-3vskA:
undetectable
2qeuB-3vskA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1g DNA LIGASE 4

(Homo sapiens)
PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C)
3 PRO A  66
ASN A 149
ARG A  79
None
0.67A 2qeuB-3w1gA:
1.8
2qeuB-3w1gA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bl0 CELL CYCLE ARREST
PROTEIN BUB3
CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF00400
(WD40)
PF08171
(Mad3_BUB1_II)
3 PRO B 316
ASN A 249
ARG A 242
None
1.09A 2qeuB-4bl0B:
undetectable
2qeuB-4bl0B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgu PROTEIN INTERACTING
WITH HSP90 1


(Saccharomyces
cerevisiae)
no annotation 3 PRO B 265
ASN B 287
ARG B 338
PRO  B 265 ( 1.1A)
ASN  B 287 ( 0.6A)
ARG  B 338 ( 0.6A)
1.01A 2qeuB-4cguB:
undetectable
2qeuB-4cguB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emk U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM5
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7


(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe)
PF01423
(LSM)
PF01423
(LSM)
3 PRO A   7
ASN C  58
ARG C  89
None
1.07A 2qeuB-4emkA:
undetectable
2qeuB-4emkA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqj HEMAGGLUTININ

(Influenza B
virus)
PF00509
(Hemagglutinin)
3 PRO A 134
ASN A 163
ARG A 262
None
0.91A 2qeuB-4fqjA:
undetectable
2qeuB-4fqjA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g92 TRANSCRIPTION FACTOR
HAPC (EUROFUNG)
HAPE


(Aspergillus
nidulans;
Aspergillus
nidulans)
PF00808
(CBFD_NFYB_HMF)
PF00808
(CBFD_NFYB_HMF)
3 PRO C  88
ASN B  52
ARG B  55
None
0.97A 2qeuB-4g92C:
undetectable
2qeuB-4g92C:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl8 OLIGOPEPTIDE ABC
TRANSPORTER OPPAIV


(Borreliella
burgdorferi)
PF00496
(SBP_bac_5)
3 PRO A 209
ASN A 522
ARG A  76
None
0.97A 2qeuB-4gl8A:
undetectable
2qeuB-4gl8A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxw ADENOSINE DEAMINASE

(Burkholderia
ambifaria)
PF00962
(A_deaminase)
3 PRO A 195
ASN A 225
ARG A 224
None
1.00A 2qeuB-4gxwA:
undetectable
2qeuB-4gxwA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htp DNA LIGASE 4

(Homo sapiens)
PF04675
(DNA_ligase_A_N)
3 PRO A  66
ASN A 149
ARG A  79
None
0.78A 2qeuB-4htpA:
undetectable
2qeuB-4htpA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594


(Pyrococcus
horikoshii)
PF00326
(Peptidase_S9)
PF07676
(PD40)
3 PRO B 586
ASN B  39
ARG B 587
None
0.96A 2qeuB-4hxeB:
undetectable
2qeuB-4hxeB:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iqe CARBOXYVINYL-CARBOXY
PHOSPHONATE
PHOSPHORYLMUTASE


(Bacillus
anthracis)
PF13714
(PEP_mutase)
3 PRO A 240
ASN A 214
ARG A 162
None
1.01A 2qeuB-4iqeA:
undetectable
2qeuB-4iqeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lrv DNA SULFUR
MODIFICATION PROTEIN
DNDE


(Escherichia
coli)
PF08870
(DndE)
3 PRO A  29
ASN A  30
ARG A  34
None
1.06A 2qeuB-4lrvA:
undetectable
2qeuB-4lrvA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m38 PROTEIN ARGININE
N-METHYLTRANSFERASE
7


(Trypanosoma
brucei)
PF06325
(PrmA)
3 PRO A 317
ASN A 255
ARG A 253
None
0.98A 2qeuB-4m38A:
undetectable
2qeuB-4m38A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m3n PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE


(Meiothermus
ruber)
PF01048
(PNP_UDP_1)
3 PRO A 127
ASN A 116
ARG A 119
None
1.00A 2qeuB-4m3nA:
undetectable
2qeuB-4m3nA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7w PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE


(Leptotrichia
buccalis)
PF01048
(PNP_UDP_1)
3 PRO A 128
ASN A 117
ARG A 120
None
1.00A 2qeuB-4m7wA:
undetectable
2qeuB-4m7wA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvw ZNUD

(Neisseria
meningitidis)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
3 PRO A 194
ASN A 706
ARG A 724
None
0.85A 2qeuB-4rvwA:
undetectable
2qeuB-4rvwA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3


(Rattus
norvegicus;
Escherichia
virus T4)
PF00001
(7tm_1)
PF00959
(Phage_lysozyme)
3 PRO A1143
ASN A1144
ARG A1148
None
0.93A 2qeuB-4u14A:
undetectable
2qeuB-4u14A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um8 INTEGRIN BETA-6

(Homo sapiens)
PF00362
(Integrin_beta)
PF17205
(PSI_integrin)
3 PRO B  45
ASN B  60
ARG B  97
None
0.95A 2qeuB-4um8B:
undetectable
2qeuB-4um8B:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upi SULFATASE FAMILY
PROTEIN


(Ruegeria
pomeroyi)
PF00884
(Sulfatase)
3 PRO A 150
ASN A 153
ARG A 157
None
1.09A 2qeuB-4upiA:
undetectable
2qeuB-4upiA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwm 3,6-DIKETOCAMPHANE
1,6 MONOOXYGENASE


(Pseudomonas
putida)
PF00296
(Bac_luciferase)
3 PRO A 208
ASN A 206
ARG A 232
FMN  A 400 (-3.8A)
None
None
1.03A 2qeuB-4uwmA:
undetectable
2qeuB-4uwmA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x33 PROTEIN ATS1

(Saccharomyces
cerevisiae)
PF00415
(RCC1)
3 PRO B 262
ASN B 240
ARG B 258
None
0.98A 2qeuB-4x33B:
undetectable
2qeuB-4x33B:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9e DEOXYGUANOSINETRIPHO
SPHATE
TRIPHOSPHOHYDROLASE


(Escherichia
coli)
PF01966
(HD)
3 PRO A 149
ASN A 170
ARG A 173
None
1.06A 2qeuB-4x9eA:
undetectable
2qeuB-4x9eA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfa PROTEIN RELATED TO
PENICILLIN ACYLASE


(Acidovorax sp.
MR-S7)
PF01804
(Penicil_amidase)
3 PRO C 188
ASN C 158
ARG C 160
None
1.01A 2qeuB-4yfaC:
undetectable
2qeuB-4yfaC:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhj MG-CHELATASE SUBUNIT
CHLH


(Synechocystis
sp. PCC 6803)
PF02514
(CobN-Mg_chel)
PF11965
(DUF3479)
3 PRO A 463
ASN A1288
ARG A1291
None
1.05A 2qeuB-4zhjA:
undetectable
2qeuB-4zhjA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
MOLYBDOPTERIN-BINDIN
G SUBUNIT


(Sulfurisphaera
tokodaii)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2)
3 PRO A 111
ASN A 282
ARG A 159
None
0.94A 2qeuB-4zohA:
undetectable
2qeuB-4zohA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zu9 ELONGATION FACTOR
SELB


(Aquifex
aeolicus)
PF00009
(GTP_EFTU)
PF09107
(SelB-wing_3)
3 PRO A  63
ASN A  71
ARG A 256
GNP  A2001 ( 4.9A)
None
None
1.06A 2qeuB-4zu9A:
undetectable
2qeuB-4zu9A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1
ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5


(Homo sapiens;
Homo sapiens)
PF12859
(ANAPC1)
PF12862
(ANAPC5)
3 PRO A  32
ASN O 260
ARG O 263
None
0.82A 2qeuB-5a31A:
undetectable
2qeuB-5a31A:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE


(Acidovorax sp.
MR-S7)
PF01804
(Penicil_amidase)
3 PRO A 390
ASN A 360
ARG A 362
None
1.02A 2qeuB-5c9iA:
undetectable
2qeuB-5c9iA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cer BD0816

(Bdellovibrio
bacteriovorus)
PF02113
(Peptidase_S13)
3 PRO A 102
ASN A 250
ARG A 100
None
1.06A 2qeuB-5cerA:
undetectable
2qeuB-5cerA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eku ARGININE
N-METHYLTRANSFERASE,
PUTATIVE


(Trypanosoma
brucei)
PF06325
(PrmA)
3 PRO A 317
ASN A 255
ARG A 253
None
0.96A 2qeuB-5ekuA:
undetectable
2qeuB-5ekuA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA


(Homo sapiens;
Escherichia
virus T4)
PF00454
(PI3_PI4_kinase)
PF00959
(Phage_lysozyme)
3 PRO A1145
ASN A1146
ARG A1150
None
0.94A 2qeuB-5eutA:
undetectable
2qeuB-5eutA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evj ARSENITE
METHYLTRANSFERASE


(Chlamydomonas
reinhardtii)
PF13847
(Methyltransf_31)
3 PRO A  77
ASN A 169
ARG A  96
None
1.09A 2qeuB-5evjA:
undetectable
2qeuB-5evjA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS


(Bacillus
halmapalus)
PF00082
(Peptidase_S8)
PF04151
(PPC)
3 PRO A 421
ASN A 365
ARG A 149
None
0.97A 2qeuB-5fbzA:
undetectable
2qeuB-5fbzA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g49 NUCLEAR
TRANSCRIPTION FACTOR
Y SUBUNIT B-6
NUCLEAR
TRANSCRIPTION FACTOR
Y SUBUNIT C-3


(Arabidopsis
thaliana;
Arabidopsis
thaliana)
PF00808
(CBFD_NFYB_HMF)
PF00808
(CBFD_NFYB_HMF)
3 PRO B  72
ASN A  67
ARG A  70
None
0.90A 2qeuB-5g49B:
undetectable
2qeuB-5g49B:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gmh TOLL-LIKE RECEPTOR 7

(Macaca mulatta)
PF00560
(LRR_1)
PF13306
(LRR_5)
PF13855
(LRR_8)
3 PRO A 102
ASN A 159
ARG A 115
None
0.77A 2qeuB-5gmhA:
undetectable
2qeuB-5gmhA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnm VITAMIN D(3)
25-HYDROXYLASE


(Pseudonocardia
autotrophica)
PF00067
(p450)
3 PRO A  24
ASN A  21
ARG A 389
None
1.02A 2qeuB-5gnmA:
undetectable
2qeuB-5gnmA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjh 4-ALPHA-GLUCANOTRANS
FERASE


(Corynebacterium
glutamicum)
PF02446
(Glyco_hydro_77)
3 PRO A  96
ASN A 151
ARG A 153
None
SO4  A 811 (-3.7A)
SO4  A 811 (-2.9A)
0.88A 2qeuB-5jjhA:
undetectable
2qeuB-5jjhA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A

(Homo sapiens)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
3 PRO A 478
ASN A 492
ARG A 494
None
0.86A 2qeuB-5jpnA:
undetectable
2qeuB-5jpnA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyo CYP101J2

(Sphingobium
yanoikuyae)
PF00067
(p450)
3 PRO A 360
ASN A 118
ARG A 114
HEM  A 501 (-4.4A)
None
None
1.09A 2qeuB-5kyoA:
undetectable
2qeuB-5kyoA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN3
26S PROTEASOME
REGULATORY SUBUNIT
RPN8


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF01399
(PCI)
PF08375
(Rpn3_C)
PF01398
(JAB)
PF13012
(MitMem_reg)
3 PRO S 482
ASN U 280
ARG U 283
None
0.93A 2qeuB-5mpdS:
2.0
2qeuB-5mpdS:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5njf METALLOPROTEASE TLDD

(Escherichia
coli)
PF01523
(PmbA_TldD)
3 PRO A 361
ASN A 338
ARG A 275
None
1.06A 2qeuB-5njfA:
undetectable
2qeuB-5njfA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1


(Glycine max)
no annotation 3 PRO A 816
ASN A 800
ARG A 809
None
0.95A 2qeuB-5tr0A:
undetectable
2qeuB-5tr0A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubk ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ


(Pseudomonas
aeruginosa)
PF01804
(Penicil_amidase)
3 PRO A 185
ASN A 155
ARG A 157
None
0.97A 2qeuB-5ubkA:
undetectable
2qeuB-5ubkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vre PUTATIVE INTEGRAL
MEMBRANE PROTEIN


(Chamaesiphon
minutus)
PF06736
(DUF1211)
3 PRO A 169
ASN A 136
ARG A 137
None
1.00A 2qeuB-5vreA:
undetectable
2qeuB-5vreA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE


(Paenibacillus
sp. 598K)
PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110)
3 PRO A 546
ASN A1175
ARG A1174
None
0.94A 2qeuB-5x7sA:
2.6
2qeuB-5x7sA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xne -

(-)
no annotation 3 PRO B  89
ASN B  57
ARG B  87
None
1.09A 2qeuB-5xneB:
undetectable
2qeuB-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus)
no annotation 3 PRO A 587
ASN A 593
ARG A 581
None
0.95A 2qeuB-6aunA:
2.3
2qeuB-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw PROBABLE
MEMBRANE-BOUND
HYDROGENASE SUBUNIT
MBHJ
MEMBRANE-BOUND
HYDROGENASE SUBUNIT
ALPHA
NADH-PLASTOQUINONE
OXIDOREDUCTASE
SUBUNIT


(Pyrococcus
furiosus;
Pyrococcus
furiosus;
Pyrococcus
furiosus)
no annotation
no annotation
no annotation
3 PRO J 133
ASN L 148
ARG N  36
SF4  J 201 ( 3.8A)
None
None
0.99A 2qeuB-6cfwJ:
undetectable
2qeuB-6cfwJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cri


(;
)
no annotation
no annotation
3 PRO G  62
ASN M 318
ARG G  35
None
1.06A 2qeuB-6criG:
2.1
2qeuB-6criG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9h GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(I) SUBUNIT
ALPHA-2
CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1


(Homo sapiens;
Homo sapiens)
no annotation
no annotation
3 PRO R 112
ASN A 348
ARG R 108
None
1.05A 2qeuB-6d9hR:
1.7
2qeuB-6d9hR:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dg4 ULP1-LIKE SUMO
PROTEASE


(Chaetomium
thermophilum)
no annotation 3 PRO A  87
ASN A 116
ARG A 118
None
0.96A 2qeuB-6dg4A:
undetectable
2qeuB-6dg4A:
undetectable