SIMILAR PATTERNS OF AMINO ACIDS FOR 2QEU_A_ACTA141

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanopyrus
kandleri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		3 VAL B  80
ASP B  81
GLU B  55
 None
 0.69A 2qeuA-1e6vB:
1.4		 2qeuA-1e6vB:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9y UREASE SUBUNIT ALPHA

(Helicobacter
pylori) 		PF00547
(Urease_gamma)
PF00699
(Urease_beta) 		3 VAL A 202
ASP A 203
GLU A 149
 None
 0.62A 2qeuA-1e9yA:
0.4		 2qeuA-1e9yA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpj GLUTAMYL-TRNA
REDUCTASE

(Methanopyrus
kandleri) 		PF00745
(GlutR_dimer)
PF01488
(Shikimate_DH)
PF05201
(GlutR_N) 		3 VAL A 244
ASP A 245
GLU A 272
 None
 0.56A 2qeuA-1gpjA:
0.3		 2qeuA-1gpjA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqo PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Zea mays) 		PF00311
(PEPcase) 		3 VAL A  67
ASP A  70
GLU A  82
 None
 0.73A 2qeuA-1jqoA:
0.6		 2qeuA-1jqoA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgd PERIPHERAL PLASMA
MEMBRANE CASK

(Homo sapiens) 		PF00625
(Guanylate_kin) 		3 VAL A 832
ASP A 831
GLU A 802
 None
None
FMT  A 601 ( 4.4A)
 0.62A 2qeuA-1kgdA:
undetectable		 2qeuA-1kgdA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o94 ELECTRON TRANSFER
FLAVOPROTEIN
BETA-SUBUNIT
ELECTRON TRANSFER
FLAVOPROTEIN
ALPHA-SUBUNIT

(Methylophilus
methylotrophus;
Methylophilus
methylotrophus) 		PF01012
(ETF)
PF01012
(ETF) 		3 VAL D  97
ASP D  98
GLU C 165
 None
 0.65A 2qeuA-1o94D:
undetectable		 2qeuA-1o94D:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		3 VAL A 433
ASP A 463
GLU A 343
 CA  A 916 (-3.6A)
CA  A 914 ( 3.4A)
CA  A 913 ( 2.5A)
 0.00A 2qeuA-1q5aA:
undetectable		 2qeuA-1q5aA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qyc PHENYLCOUMARAN
BENZYLIC ETHER
REDUCTASE PT1

(Pinus taeda) 		PF05368
(NmrA) 		3 VAL A 118
ASP A 119
GLU A 113
 None
 0.70A 2qeuA-1qycA:
undetectable		 2qeuA-1qycA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su0 NIFU LIKE PROTEIN
ISCU

(Streptococcus
pyogenes) 		PF01592
(NifU_N) 		3 VAL B  13
ASP B  16
GLU B 111
 None
 0.46A 2qeuA-1su0B:
2.1		 2qeuA-1su0B:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anu HYPOTHETICAL PROTEIN
TM0559

(Thermotoga
maritima) 		no annotation 3 VAL A  29
ASP A  30
GLU A  80
 None
 0.43A 2qeuA-2anuA:
undetectable		 2qeuA-2anuA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cgj L-RHAMNULOSE KINASE

(Escherichia
coli) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 VAL A 447
ASP A 448
GLU A 288
 None
 0.70A 2qeuA-2cgjA:
undetectable		 2qeuA-2cgjA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2de2 DIBENZOTHIOPHENE
DESULFURIZATION
ENZYME B

(Rhodococcus sp.
IGTS8) 		no annotation 3 VAL A 184
ASP A 185
GLU A 156
 None
 0.75A 2qeuA-2de2A:
undetectable		 2qeuA-2de2A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwc 433AA LONG
HYPOTHETICAL
PHOSPHORIBOSYLGLYCIN
AMIDE FORMYL
TRANSFERASE

(Pyrococcus
horikoshii) 		PF02222
(ATP-grasp) 		3 VAL A 397
ASP A 396
GLU A 250
 None
 0.64A 2qeuA-2dwcA:
undetectable		 2qeuA-2dwcA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gas ISOFLAVONE REDUCTASE

(Medicago sativa) 		PF05368
(NmrA) 		3 VAL A 128
ASP A 129
GLU A 123
 None
 0.65A 2qeuA-2gasA:
undetectable		 2qeuA-2gasA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hwv DNA-BINDING RESPONSE
REGULATOR VICR

(Enterococcus
faecalis) 		PF00486
(Trans_reg_C) 		3 VAL A 194
ASP A 193
GLU A 179
 SO4  A 101 (-4.9A)
SO4  A 102 (-3.1A)
SO4  A 101 (-4.9A)
 0.73A 2qeuA-2hwvA:
undetectable		 2qeuA-2hwvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7r CONSERVED DOMAIN
PROTEIN

(Streptococcus
pneumoniae) 		no annotation 3 VAL A  71
ASP A  70
GLU A  97
 None
 0.75A 2qeuA-2i7rA:
undetectable		 2qeuA-2i7rA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipi ACLACINOMYCIN
OXIDOREDUCTASE
(AKNOX)

(Streptomyces
galilaeus) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 VAL A 453
ASP A 454
GLU A  73
 None
 0.53A 2qeuA-2ipiA:
undetectable		 2qeuA-2ipiA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbw 2,6-DIHYDROXY-PSEUDO
-OXYNICOTINE
HYDROLASE

(Paenarthrobacter
nicotinovorans) 		PF06500
(DUF1100) 		3 VAL A 197
ASP A 198
GLU A 230
 None
 0.63A 2qeuA-2jbwA:
2.6		 2qeuA-2jbwA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oxl HYPOTHETICAL PROTEIN
YMGB

(Escherichia
coli) 		PF10798
(YmgB) 		3 VAL A  72
ASP A  71
GLU A  30
 None
 0.65A 2qeuA-2oxlA:
3.1		 2qeuA-2oxlA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p19 TRANSCRIPTIONAL
REGULATOR

(Corynebacterium
glutamicum) 		PF07702
(UTRA) 		3 VAL A  64
ASP A  63
GLU A  68
 None
 0.72A 2qeuA-2p19A:
undetectable		 2qeuA-2p19A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p22 SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
HYPOTHETICAL 12.0
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF09454
(Vps23_core)
PF09452
(Mvb12) 		3 VAL A 332
ASP A 335
GLU D   6
 None
None
SO4  C 215 (-4.2A)
 0.75A 2qeuA-2p22A:
2.4		 2qeuA-2p22A:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qeu PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE

(Paraburkholderia
xenovorans) 		PF02627
(CMD) 		3 VAL A  98
ASP A  99
GLU A 132
 ACT  A 141 ( 4.5A)
ACT  A 141 (-3.7A)
ACT  A 141 (-3.6A)
 0.00A 2qeuA-2qeuA:
26.9		 2qeuA-2qeuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qul D-TAGATOSE
3-EPIMERASE

(Pseudomonas
cichorii) 		PF01261
(AP_endonuc_2) 		3 VAL A 154
ASP A 185
GLU A 158
 None
MN  A 291 (-3.1A)
None
 0.69A 2qeuA-2qulA:
1.1		 2qeuA-2qulA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsg VARIANT SURFACE
GLYCOPROTEIN ILTAT
1.24

(Trypanosoma
brucei) 		PF00913
(Trypan_glycop) 		3 VAL A 157
ASP A 156
GLU A  15
 None
 0.75A 2qeuA-2vsgA:
undetectable		 2qeuA-2vsgA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtn EST1E

(Butyrivibrio
proteoclasticus) 		PF08386
(Abhydrolase_4)
PF12146
(Hydrolase_4) 		3 VAL A  87
ASP A  88
GLU A 118
 None
 0.73A 2qeuA-2wtnA:
undetectable		 2qeuA-2wtnA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xts SULFITE
DEHYDROGENASE
CYTOCHROME

(Paracoccus
pantotrophus;
Paracoccus
pantotrophus) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer)
PF13442
(Cytochrome_CBB3) 		3 VAL B 203
ASP B 204
GLU A 425
 None
 0.47A 2qeuA-2xtsB:
undetectable		 2qeuA-2xtsB:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3s TAML

(Streptomyces
sp. 307-9) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 VAL A 450
ASP A 451
GLU A  65
 None
 0.48A 2qeuA-2y3sA:
undetectable		 2qeuA-2y3sA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN

(Oryza sativa) 		PF08414
(NADPH_Ox)
PF13499
(EF-hand_7) 		3 VAL A 196
ASP A 200
GLU A 193
 None
 0.75A 2qeuA-3a8rA:
undetectable		 2qeuA-3a8rA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bio OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Porphyromonas
gingivalis) 		PF01408
(GFO_IDH_MocA)
PF16654
(DAPDH_C) 		3 VAL A 221
ASP A 222
GLU A 188
 None
 0.71A 2qeuA-3bioA:
undetectable		 2qeuA-3bioA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvq NOTI RESTRICTION
ENDONUCLEASE

(Nocardia
otitidiscaviarum) 		PF12183
(NotI) 		3 VAL A 326
ASP A 327
GLU A 296
 None
 0.62A 2qeuA-3bvqA:
undetectable		 2qeuA-3bvqA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwu OUTER MEMBRANE USHER
PROTEIN FIMD,
N-TERMINAL DOMAIN

(Escherichia
coli) 		PF13954
(PapC_N) 		3 VAL D 106
ASP D 105
GLU D  27
 None
 0.74A 2qeuA-3bwuD:
undetectable		 2qeuA-3bwuD:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ck6 PUTATIVE MEMBRANE
TRANSPORT PROTEIN

(Vibrio
parahaemolyticus) 		PF01544
(CorA) 		3 VAL A  54
ASP A  55
GLU A  45
 None
 0.71A 2qeuA-3ck6A:
1.7		 2qeuA-3ck6A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3edp LIN2111 PROTEIN

(Listeria
innocua) 		PF00392
(GntR)
PF07702
(UTRA) 		3 VAL A  51
ASP A  52
GLU A  33
 None
 0.53A 2qeuA-3edpA:
undetectable		 2qeuA-3edpA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvq FE(3+) IONS IMPORT
ATP-BINDING PROTEIN
FBPC

(Neisseria
gonorrhoeae) 		PF00005
(ABC_tran) 		3 VAL A  86
ASP A 163
GLU A  88
 None
CA  A 360 ( 4.0A)
None
 0.70A 2qeuA-3fvqA:
undetectable		 2qeuA-3fvqA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2u RAVER-1

(Homo sapiens) 		PF00076
(RRM_1) 		3 VAL B  70
ASP B  69
GLU B  74
 None
 0.71A 2qeuA-3h2uB:
undetectable		 2qeuA-3h2uB:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h3e UNCHARACTERIZED
PROTEIN TM1679

(Thermotoga
maritima) 		PF00753
(Lactamase_B) 		3 VAL A  37
ASP A  36
GLU A  16
 None
 0.44A 2qeuA-3h3eA:
undetectable		 2qeuA-3h3eA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbc CHOLOYLGLYCINE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF02275
(CBAH) 		3 VAL A 141
ASP A 142
GLU A 190
 None
 0.54A 2qeuA-3hbcA:
undetectable		 2qeuA-3hbcA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hja GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Borreliella
burgdorferi) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 VAL A 254
ASP A 253
GLU A 258
 None
 0.72A 2qeuA-3hjaA:
undetectable		 2qeuA-3hjaA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpa AMIDOHYDROLASE

(unidentified) 		PF01979
(Amidohydro_1) 		3 VAL A 428
ASP A 426
GLU A  48
 None
 0.74A 2qeuA-3hpaA:
undetectable		 2qeuA-3hpaA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus) 		no annotation 3 VAL H 256
ASP H 257
GLU H 291
 None
 0.50A 2qeuA-3j97H:
3.5		 2qeuA-3j97H:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9o INTRACELLULAR GROWTH
LOCUS PROTEIN B

(Francisella
tularensis) 		PF05943
(VipB) 		3 VAL B 125
ASP B 124
GLU B 129
 None
 0.71A 2qeuA-3j9oB:
undetectable		 2qeuA-3j9oB:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jze DIHYDROOROTASE

(Salmonella
enterica) 		PF01979
(Amidohydro_1) 		3 VAL A  53
ASP A  54
GLU A  89
 None
 0.66A 2qeuA-3jzeA:
undetectable		 2qeuA-3jzeA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jzj ACARBOSE/MALTOSE
BINDING PROTEIN GACH

(Streptomyces
glaucescens) 		PF13416
(SBP_bac_8) 		3 VAL A  52
ASP A  51
GLU A  41
 None
 0.76A 2qeuA-3jzjA:
undetectable		 2qeuA-3jzjA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfo NUCLEOPORIN NUP133

(Saccharomyces
cerevisiae) 		no annotation 3 VAL A1081
ASP A1082
GLU A1130
 None
 0.59A 2qeuA-3kfoA:
undetectable		 2qeuA-3kfoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ltw ARYLAMINE
N-ACETYLTRANSFERASE
NAT

(Mycobacterium
marinum) 		PF00797
(Acetyltransf_2) 		3 VAL A 246
ASP A 247
GLU A 267
 None
 0.68A 2qeuA-3ltwA:
undetectable		 2qeuA-3ltwA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3men ACETYLPOLYAMINE
AMINOHYDROLASE

(Burkholderia
pseudomallei) 		PF00850
(Hist_deacetyl) 		3 VAL A 160
ASP A 161
GLU A 201
 None
 0.71A 2qeuA-3menA:
undetectable		 2qeuA-3menA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml6 CHIMERIC COMPLEX
BETWEEN PROTEIN
DISHEVLLED2 HOMOLOG
DVL-2 AND CLATHRIN
ADAPTOR AP-2 COMPLEX
SUBUNIT MU

(Mus musculus;
Rattus
norvegicus) 		PF00610
(DEP)
PF00928
(Adap_comp_sub) 		3 VAL A 459
ASP A 460
GLU A 499
 None
 0.65A 2qeuA-3ml6A:
undetectable		 2qeuA-3ml6A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqq PUTATIVE LIPOPROTEIN

(Bacteroides
ovatus) 		PF16129
(DUF4841)
PF16130
(DUF4842) 		3 VAL A 289
ASP A 281
GLU A 286
 None
 0.72A 2qeuA-3oqqA:
undetectable		 2qeuA-3oqqA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator) 		no annotation 3 VAL B 263
ASP B 264
GLU B 186
 None
 0.61A 2qeuA-3ozvB:
2.5		 2qeuA-3ozvB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pua PHD FINGER PROTEIN 2

(Homo sapiens) 		PF02373
(JmjC) 		3 VAL A 178
ASP A 179
GLU A 150
 None
 0.59A 2qeuA-3puaA:
undetectable		 2qeuA-3puaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL-COENZYME M
REDUCTASE, BETA
SUBUNIT

(uncultured
archaeon) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		3 VAL B  76
ASP B  77
GLU B  51
 None
 0.70A 2qeuA-3sqgB:
1.0		 2qeuA-3sqgB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u8e PAPAIN-LIKE CYSTEINE
PROTEASE

(Crocus sativus) 		PF00112
(Peptidase_C1) 		3 VAL A  54
ASP A  55
GLU A  50
 None
NA  A 224 (-2.9A)
None
 0.72A 2qeuA-3u8eA:
undetectable		 2qeuA-3u8eA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va7 KLLA0E08119P

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 VAL A1554
ASP A1555
GLU A1528
 None
 0.31A 2qeuA-3va7A:
undetectable		 2qeuA-3va7A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmr PROLINE
IMINOPEPTIDASE

(Streptomyces
halstedii) 		PF00561
(Abhydrolase_1) 		3 VAL A 290
ASP A 293
GLU A 270
 None
 0.73A 2qeuA-3wmrA:
undetectable		 2qeuA-3wmrA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wst PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Caenorhabditis
elegans) 		PF13649
(Methyltransf_25) 		3 VAL A 216
ASP A 215
GLU A 536
 None
 0.64A 2qeuA-3wstA:
undetectable		 2qeuA-3wstA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwz D-LACTATE
DEHYDROGENASE
(FERMENTATIVE)

(Pseudomonas
aeruginosa) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 VAL A 259
ASP A 258
GLU A 263
 None
 0.76A 2qeuA-3wwzA:
undetectable		 2qeuA-3wwzA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ak9 CPFTSY

(Physcomitrella
patens) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		3 VAL A 135
ASP A 136
GLU A 118
 None
 0.69A 2qeuA-4ak9A:
undetectable		 2qeuA-4ak9A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akk NITRATE REGULATORY
PROTEIN

(Klebsiella
oxytoca) 		PF03861
(ANTAR)
PF08376
(NIT) 		3 VAL A  75
ASP A  76
GLU A  49
 None
EDO  A1394 (-3.3A)
None
 0.40A 2qeuA-4akkA:
2.4		 2qeuA-4akkA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgb PUTATIVE SUGAR
KINASE MK0840

(Methanopyrus
kandleri) 		PF03702
(AnmK) 		3 VAL A 113
ASP A 144
GLU A 115
 None
K  A1357 ( 2.4A)
None
 0.70A 2qeuA-4bgbA:
undetectable		 2qeuA-4bgbA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6x THIAZOLINE
OXIDASE/SUBTILISIN-L
IKE PROTEASE

(Prochloron
didemni) 		PF00082
(Peptidase_S8) 		3 VAL A 740
ASP A 741
GLU A 764
 None
 0.70A 2qeuA-4h6xA:
undetectable		 2qeuA-4h6xA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwh BAG FAMILY MOLECULAR
CHAPERONE REGULATOR
4

(Arabidopsis
thaliana) 		PF02179
(BAG) 		3 VAL A 149
ASP A 150
GLU A 204
 None
 0.48A 2qeuA-4hwhA:
3.3		 2qeuA-4hwhA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy3 PHOSPHOGLYCERATE
OXIDOREDUCTASE

(Rhizobium etli) 		PF02826
(2-Hacid_dh_C) 		3 VAL A 269
ASP A 268
GLU A 273
 None
 0.76A 2qeuA-4hy3A:
undetectable		 2qeuA-4hy3A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		3 VAL A 252
ASP A 254
GLU A 198
 None
 0.74A 2qeuA-4iglA:
undetectable		 2qeuA-4iglA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4im4 ENDOGLUCANASE E

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		3 VAL A 213
ASP A 212
GLU A 161
 None
 0.74A 2qeuA-4im4A:
1.6		 2qeuA-4im4A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgv GLUCOSE-6-PHOSPHATE
1-DEHYDROGENASE

(Mycobacterium
avium) 		PF00479
(G6PD_N)
PF02781
(G6PD_C) 		3 VAL A 170
ASP A 171
GLU A 141
 None
 0.74A 2qeuA-4lgvA:
undetectable		 2qeuA-4lgvA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lsw D-2-HYDROXYACID
DEHYDROGENSASE
PROTEIN

(Ketogulonicigenium
vulgare) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 VAL A 259
ASP A 258
GLU A 263
 None
 0.62A 2qeuA-4lswA:
undetectable		 2qeuA-4lswA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mrq PHOSPHOMANNOMUTASE/P
HOSPHOGLUCOMUTASE

(Pseudomonas
aeruginosa) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 VAL A 271
ASP A 270
GLU A 334
 None
PGE  A 509 ( 4.9A)
None
 0.70A 2qeuA-4mrqA:
undetectable		 2qeuA-4mrqA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n17 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Burkholderia
ambifaria) 		PF03480
(DctP) 		3 VAL A  34
ASP A  33
GLU A  73
 None
None
GTR  A 401 ( 2.9A)
 0.74A 2qeuA-4n17A:
undetectable		 2qeuA-4n17A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n17 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Burkholderia
ambifaria) 		PF03480
(DctP) 		3 VAL A 321
ASP A 322
GLU A 312
 None
CA  A 403 (-2.5A)
CA  A 403 ( 4.9A)
 0.49A 2qeuA-4n17A:
undetectable		 2qeuA-4n17A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8y PUTATIVE TRAP-TYPE
C4-DICARBOXYLATE
TRANSPORT SYSTEM,
BINDING PERIPLASMIC
PROTEIN (DCTP
SUBUNIT)

(Bradyrhizobium
sp. BTAi1) 		PF03480
(DctP) 		3 VAL A  30
ASP A  29
GLU A  69
 None
None
GTR  A 402 (-2.9A)
 0.76A 2qeuA-4n8yA:
undetectable		 2qeuA-4n8yA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nq8 PUTATIVE PERIPLASMIC
SUBSTRATE-BINDING
TRANSPORT PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		3 VAL A 271
ASP A 272
GLU A 144
 None
 0.59A 2qeuA-4nq8A:
undetectable		 2qeuA-4nq8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4o DNA POLYMERASE BETA

(Leishmania
infantum) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 VAL A 122
ASP A 123
GLU A  98
 None
 0.73A 2qeuA-4p4oA:
undetectable		 2qeuA-4p4oA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9k TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Verminephrobacter
eiseniae) 		PF03480
(DctP) 		3 VAL A 281
ASP A 282
GLU A 154
 None
 0.66A 2qeuA-4p9kA:
undetectable		 2qeuA-4p9kA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pdh TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Polaromonas sp.
JS666) 		PF03480
(DctP) 		3 VAL A 281
ASP A 282
GLU A 154
 None
 0.71A 2qeuA-4pdhA:
undetectable		 2qeuA-4pdhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pht TYPE II SECRETION
SYSTEM PROTEIN L

(Vibrio
vulnificus) 		PF05134
(T2SSL) 		3 VAL X  93
ASP X  94
GLU X  86
 None
 0.70A 2qeuA-4phtX:
undetectable		 2qeuA-4phtX:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q66 PROTEIN BCH1

(Saccharomyces
cerevisiae) 		no annotation 3 VAL K 320
ASP K 321
GLU K 316
 None
 0.74A 2qeuA-4q66K:
2.8		 2qeuA-4q66K:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 VAL A 145
ASP A 144
GLU A 178
 None
 0.59A 2qeuA-4rjkA:
undetectable		 2qeuA-4rjkA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v19 MITORIBOSOMAL
PROTEIN UL2M, MRPL2

(Sus scrofa) 		PF00181
(Ribosomal_L2)
PF03947
(Ribosomal_L2_C) 		3 VAL D 251
ASP D 252
GLU D 156
 U  A 861 ( 4.4A)
None
None
 0.75A 2qeuA-4v19D:
undetectable		 2qeuA-4v19D:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x04 SOLUTE BINDING
PROTEIN

(Citrobacter
koseri) 		PF03480
(DctP) 		3 VAL A  35
ASP A  34
GLU A  74
 BDP  A 401 (-4.9A)
None
BDP  A 401 ( 2.9A)
 0.75A 2qeuA-4x04A:
undetectable		 2qeuA-4x04A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2o CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Francisella
tularensis) 		no annotation 3 VAL A 434
ASP A 435
GLU A 385
 None
 0.57A 2qeuA-5b2oA:
2.7		 2qeuA-5b2oA:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzz DESMOPLAKIN

(Homo sapiens) 		PF00681
(Plectin) 		3 VAL A2069
ASP A2070
GLU A2090
 None
 0.50A 2qeuA-5dzzA:
2.6		 2qeuA-5dzzA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fkc BETA-FRUCTOFURANOSID
ASE

(Xanthophyllomyces
dendrorhous) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 VAL A 461
ASP A 418
GLU A 463
 None
 0.64A 2qeuA-5fkcA:
undetectable		 2qeuA-5fkcA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gj8 ACYL-COA
DEHYDROGENASE TYPE 2
DOMAIN PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		3 VAL A  14
ASP A  13
GLU A  72
 None
 0.70A 2qeuA-5gj8A:
undetectable		 2qeuA-5gj8A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gj8 ACYL-COA
DEHYDROGENASE TYPE 2
DOMAIN PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF02771
(Acyl-CoA_dh_N) 		3 VAL D  14
ASP D  13
GLU D  72
 None
 0.70A 2qeuA-5gj8D:
2.3		 2qeuA-5gj8D:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 VAL A1554
ASP A1555
GLU A1528
 None
 0.35A 2qeuA-5i8iA:
undetectable		 2qeuA-5i8iA:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inw PUTATIVE
ANGIOTENSINOGEN

(Lampetra
fluviatilis) 		PF00079
(Serpin) 		3 VAL A 229
ASP A 228
GLU A 410
 None
 0.65A 2qeuA-5inwA:
undetectable		 2qeuA-5inwA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5it9 RIBOSOMAL PROTEIN
RACK1

(Kluyveromyces
lactis) 		PF01092
(Ribosomal_S6e) 		3 VAL g 316
ASP g 314
GLU g  15
 None
 0.70A 2qeuA-5it9g:
undetectable		 2qeuA-5it9g:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5izd D-GLYCERALDEHYDE
DEHYDROGENASE
(NADP(+))

(Thermoplasma
acidophilum) 		PF00171
(Aldedh) 		3 VAL A 101
ASP A 102
GLU A  83
 None
 0.70A 2qeuA-5izdA:
undetectable		 2qeuA-5izdA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL

(Bos taurus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		3 VAL A 375
ASP A 378
GLU A  28
 None
 0.71A 2qeuA-5nmiA:
undetectable		 2qeuA-5nmiA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5no8 BACCELL_00875

(Bacteroides
cellulosilyticus) 		no annotation 3 VAL A 440
ASP A 441
GLU A 391
 None
 0.71A 2qeuA-5no8A:
undetectable		 2qeuA-5no8A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5noi ROUNDABOUT HOMOLOG 2

(Homo sapiens) 		no annotation 3 VAL A 431
ASP A 432
GLU A 507
 None
 0.62A 2qeuA-5noiA:
undetectable		 2qeuA-5noiA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5suz SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-2

(Homo sapiens) 		PF00610
(DEP) 		3 VAL A 459
ASP A 460
GLU A 499
 None
 0.39A 2qeuA-5suzA:
undetectable		 2qeuA-5suzA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tcm UNCHARACTERIZED
PROTEIN

(Leishmania
donovani) 		PF00439
(Bromodomain) 		3 VAL A  28
ASP A  50
GLU A  32
 None
 0.68A 2qeuA-5tcmA:
undetectable		 2qeuA-5tcmA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v72 NADPH-DEPENDENT
GLYOXYLATE/HYDROXYPY
RUVATE REDUCTASE

(Sinorhizobium
meliloti) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 VAL A 255
ASP A 254
GLU A 259
 None
 0.72A 2qeuA-5v72A:
undetectable		 2qeuA-5v72A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wz4 23S RRNA-SPECIFIC
ENDONUCLEASE VAPC20

(Mycobacterium
tuberculosis) 		no annotation 3 VAL A  97
ASP A  98
GLU A  43
 None
 0.58A 2qeuA-5wz4A:
undetectable		 2qeuA-5wz4A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9d ACYL-COENZYME A
OXIDASE 1

(Yarrowia
lipolytica) 		no annotation 3 VAL A 609
ASP A 610
GLU A 585
 None
 0.44A 2qeuA-5y9dA:
undetectable		 2qeuA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd3 CYTOSOLIC PURINE
5'-NUCLEOTIDASE

(Homo sapiens) 		no annotation 3 VAL A 205
ASP A 206
GLU A 161
 None
 0.54A 2qeuA-6dd3A:
undetectable		 2qeuA-6dd3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 3 VAL A 337
ASP A 336
GLU A 499
 None
 0.74A 2qeuA-6ei1A:
undetectable		 2qeuA-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2

(Mus musculus) 		no annotation 3 VAL A 164
ASP A 165
GLU A 201
 None
 0.59A 2qeuA-6fv5A:
undetectable		 2qeuA-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8pch CATHEPSIN H

(Sus scrofa) 		PF00112
(Peptidase_C1) 		3 VAL A 110
ASP A 109
GLU A  73
 NAG  A 213 ( 4.5A)
None
NAG  A 213 ( 3.0A)
 0.73A 2qeuA-8pchA:
undetectable		 2qeuA-8pchA:
23.98