SIMILAR PATTERNS OF AMINO ACIDS FOR 2QEI_A_CXXA802_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cm8 PHOSPHORYLATED MAP
KINASE P38-GAMMA

(Homo sapiens) 		PF00069
(Pkinase) 		4 SER A 229
ARG A 189
ARG A 192
ILE A 197
 None
PTR  A 185 ( 3.6A)
PTR  A 185 ( 3.1A)
None
 1.15A 2qeiA-1cm8A:
0.0		 2qeiA-1cm8A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ded CYCLODEXTRIN
GLUCANOTRANSFERASE

(Bacillus sp.
1011) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 SER A 310
ARG A 284
PHE A 285
PHE A 348
 None
 1.22A 2qeiA-1dedA:
0.0		 2qeiA-1dedA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ

(Escherichia
virus G4) 		PF02305
(Phage_F) 		4 SER 1  62
PHE 1 242
ILE 1  66
PHE 1 268
 None
 1.24A 2qeiA-1gff1:
0.0		 2qeiA-1gff1:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT
II

(Salmonella
enterica) 		PF00117
(GATase) 		4 ARG B 130
PHE B 168
ILE B 111
PHE B 119
 None
 1.17A 2qeiA-1i1qB:
undetectable		 2qeiA-1i1qB:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7q TRPG

(Serratia
marcescens) 		PF00117
(GATase) 		4 ARG B 132
PHE B 171
ILE B 113
PHE B 121
 None
 1.10A 2qeiA-1i7qB:
0.0		 2qeiA-1i7qB:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcl CYCLODEXTRIN
GLYCOSYLTRANSFERASE

(Bacillus
circulans) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 SER A 310
ARG A 284
PHE A 285
PHE A 348
 None
 1.11A 2qeiA-1kclA:
0.0		 2qeiA-1kclA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pdu NUCLEAR HORMONE
RECEPTOR HR38

(Drosophila
melanogaster) 		PF00104
(Hormone_recep) 		4 SER A 365
ARG A 403
PHE A 400
PHE A 432
 None
 1.25A 2qeiA-1pduA:
0.0		 2qeiA-1pduA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rlm PHOSPHATASE

(Escherichia
coli) 		PF08282
(Hydrolase_3) 		4 ARG A  25
PHE A  26
ILE A 259
PHE A  40
 None
 1.19A 2qeiA-1rlmA:
0.0		 2qeiA-1rlmA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaa PROTEIN
(ATP-DEPENDENT DNA
HELICASE REP.)

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		4 SER A 431
PHE A 402
ILE A 405
PHE A 456
 None
 1.19A 2qeiA-1uaaA:
0.0		 2qeiA-1uaaA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT

(Pyrococcus
horikoshii) 		PF01896
(DNA_primase_S) 		4 SER A 271
ARG A 216
ILE A 124
PHE A 279
 None
 1.21A 2qeiA-1v33A:
undetectable		 2qeiA-1v33A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6m GALACTOSE-BINDING
LECTIN

(Arachis
hypogaea) 		PF00139
(Lectin_legB) 		4 ARG A  45
PHE A 206
ILE A  85
PHE A  69
 None
 1.22A 2qeiA-1v6mA:
undetectable		 2qeiA-1v6mA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		4 SER C 758
ARG C 365
ILE C 374
PHE C 376
 None
 1.16A 2qeiA-1w36C:
undetectable		 2qeiA-1w36C:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wko TERMINAL FLOWER 1
PROTEIN

(Arabidopsis
thaliana) 		PF01161
(PBP) 		4 ARG A 143
PHE A 146
ILE A 140
PHE A 151
 None
 1.18A 2qeiA-1wkoA:
undetectable		 2qeiA-1wkoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xcf TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Escherichia
coli) 		PF00290
(Trp_syntA) 		4 ARG A 140
PHE A 139
ILE A 111
PHE A 107
 None
 0.96A 2qeiA-1xcfA:
undetectable		 2qeiA-1xcfA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkt FATTY ACID SYNTHASE

(Homo sapiens) 		PF00975
(Thioesterase) 		4 ARG A2220
PHE A2375
ILE A2404
PHE A2371
 None
 1.12A 2qeiA-1xktA:
undetectable		 2qeiA-1xktA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y96 GEM-ASSOCIATED
PROTEIN 7

(Homo sapiens) 		PF11095
(Gemin7) 		4 ARG B  87
PHE B  80
ILE B 124
PHE B 102
 None
 1.23A 2qeiA-1y96B:
undetectable		 2qeiA-1y96B:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zup HYPOTHETICAL PROTEIN
TM1739

(Thermotoga
maritima) 		PF09376
(NurA) 		4 SER A 201
ARG A 247
PHE A 250
ILE A 246
 None
 0.85A 2qeiA-1zupA:
undetectable		 2qeiA-1zupA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17

(Homo sapiens) 		PF00615
(RGS) 		4 SER X 107
ARG X  99
PHE X  98
PHE X  85
 None
 1.17A 2qeiA-1zv4X:
2.0		 2qeiA-1zv4X:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2n PEPTIDYLPROLYL
ISOMERASE DOMAIN AND
WD REPEAT CONTAINING
1

(Homo sapiens) 		PF00160
(Pro_isomerase) 		4 SER A 523
PHE A 592
ILE A 594
PHE A 533
 None
 1.29A 2qeiA-2a2nA:
undetectable		 2qeiA-2a2nA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw4 LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 SER A 817
ARG A 820
ARG A 824
ILE A 825
 None
 1.27A 2qeiA-2dw4A:
undetectable		 2qeiA-2dw4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fr1 ERYTHROMYCIN
SYNTHASE, ERYAI

(Saccharopolyspora
erythraea) 		PF08659
(KR) 		4 ARG A1890
ARG A1893
PHE A1894
PHE A1805
 None
 1.24A 2qeiA-2fr1A:
undetectable		 2qeiA-2fr1A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ihd REGULATOR OF
G-PROTEIN SIGNALING
8

(Homo sapiens) 		PF00615
(RGS) 		4 SER A  79
ARG A  71
PHE A  70
PHE A  57
 None
 1.12A 2qeiA-2ihdA:
2.9		 2qeiA-2ihdA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox)
PF04945
(YHS) 		4 ARG A 120
ARG A 128
PHE A 122
PHE A 188
 None
 1.29A 2qeiA-2inpA:
undetectable		 2qeiA-2inpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kl5 UNCHARACTERIZED
PROTEIN YUTD

(Bacillus
subtilis) 		PF06265
(DUF1027) 		4 ARG A  38
PHE A  35
ILE A  15
PHE A  20
 None
 1.00A 2qeiA-2kl5A:
undetectable		 2qeiA-2kl5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2v MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 3

(Homo sapiens) 		PF00564
(PB1) 		4 ARG B  56
PHE B  49
ILE B  58
PHE B  60
 None
 1.12A 2qeiA-2o2vB:
undetectable		 2qeiA-2o2vB:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oys HYPOTHETICAL PROTEIN
SP1951

(Streptococcus
pneumoniae) 		PF03358
(FMN_red) 		4 SER A  44
ARG A 104
PHE A 101
ILE A 105
 None
 1.05A 2qeiA-2oysA:
undetectable		 2qeiA-2oysA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbe AMINOGLYCOSIDE
6-ADENYLYLTRANSFERAS
E

(Bacillus
subtilis) 		PF04439
(Adenyl_transf) 		4 ARG A  68
PHE A  65
ILE A  64
PHE A  14
 None
 1.18A 2qeiA-2pbeA:
undetectable		 2qeiA-2pbeA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qv2 INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE OCRL-1

(Homo sapiens) 		PF00620
(RhoGAP) 		4 ARG A 274
PHE A 277
ILE A 244
PHE A 331
 ARG  A 274 ( 0.6A)
PHE  A 277 ( 1.3A)
ILE  A 244 ( 0.7A)
PHE  A 331 ( 1.3A)
 1.28A 2qeiA-2qv2A:
undetectable		 2qeiA-2qv2A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rag DIPEPTIDASE

(Caulobacter
vibrioides) 		PF01244
(Peptidase_M19) 		4 ARG A  62
PHE A  60
ILE A  67
PHE A  95
 None
 1.18A 2qeiA-2ragA:
0.6		 2qeiA-2ragA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfz CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Melanocarpus
albomyces) 		PF00840
(Glyco_hydro_7) 		4 SER A 426
ARG A 420
ILE A 419
PHE A 120
 None
 1.21A 2qeiA-2rfzA:
undetectable		 2qeiA-2rfzA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzz N-METHYL-L-TRYPTOPHA
N OXIDASE

(Escherichia
coli) 		PF01266
(DAO) 		4 ARG A 228
PHE A 235
ILE A 129
PHE A 238
 None
 1.25A 2qeiA-2uzzA:
undetectable		 2qeiA-2uzzA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v26 MYOSIN VI

(Sus scrofa) 		PF00063
(Myosin_head) 		4 SER A 150
ARG A 667
PHE A 665
ILE A 488
 None
 1.12A 2qeiA-2v26A:
2.0		 2qeiA-2v26A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9q ROUNDABOUT HOMOLOG 1

(Homo sapiens) 		PF07679
(I-set)
PF13927
(Ig_3) 		4 SER A 117
ARG A 131
PHE A 129
ILE A 132
 None
 1.19A 2qeiA-2v9qA:
undetectable		 2qeiA-2v9qA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w7y PROBABLE SUGAR ABC
TRANSPORTER,
SUGAR-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF13416
(SBP_bac_8) 		4 ARG A 207
PHE A 209
ILE A 398
PHE A 237
 A2G  A1428 (-3.3A)
None
None
None
 1.21A 2qeiA-2w7yA:
undetectable		 2qeiA-2w7yA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x25 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
A

(Homo sapiens) 		PF00160
(Pro_isomerase) 		4 SER B  40
PHE B 112
ILE B 114
PHE B  53
 None
 1.13A 2qeiA-2x25B:
undetectable		 2qeiA-2x25B:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhs NUCLEAR HORMONE
RECEPTOR FTZ-F1

(Drosophila
melanogaster) 		PF00104
(Hormone_recep) 		4 SER A 794
ARG A 798
PHE A 800
PHE A 853
 None
 1.25A 2qeiA-2xhsA:
undetectable		 2qeiA-2xhsA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0l EARLY ANTIGEN
PROTEIN D

(Human
gammaherpesvirus
4) 		PF04929
(Herpes_DNAp_acc) 		4 SER A 291
ARG A 266
ILE A 272
PHE A 295
 None
 1.18A 2qeiA-2z0lA:
undetectable		 2qeiA-2z0lA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE

(Geobacillus
kaustophilus) 		PF00551
(Formyl_trans_N) 		4 SER A   9
PHE A  57
ILE A  72
PHE A  68
 None
 1.21A 2qeiA-3av3A:
undetectable		 2qeiA-3av3A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3j PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Escherichia
coli) 		PF01380
(SIS) 		4 SER A  30
PHE A 197
ILE A 192
PHE A 340
 None
 1.19A 2qeiA-3c3jA:
undetectable		 2qeiA-3c3jA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fkq NTRC-LIKE TWO-DOMAIN
PROTEIN

([Eubacterium]
rectale) 		PF13614
(AAA_31) 		4 SER A 124
PHE A 157
ILE A 201
PHE A 211
 None
 1.27A 2qeiA-3fkqA:
undetectable		 2qeiA-3fkqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		4 SER A 554
PHE A 493
ILE A 489
PHE A 496
 None
 1.02A 2qeiA-3hjeA:
undetectable		 2qeiA-3hjeA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hy8 PYRIDOXINE-5'-PHOSPH
ATE OXIDASE

(Homo sapiens) 		PF01243
(Putative_PNPOx)
PF10590
(PNP_phzG_C) 		4 ARG A 138
PHE A 218
ILE A 230
PHE A 232
 None
 1.05A 2qeiA-3hy8A:
undetectable		 2qeiA-3hy8A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3n KELCH-LIKE PROTEIN
11

(Homo sapiens) 		PF00651
(BTB)
PF07707
(BACK) 		4 ARG A 229
PHE A 232
ILE A 228
PHE A 241
 None
 1.03A 2qeiA-3i3nA:
undetectable		 2qeiA-3i3nA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1

(Rattus
norvegicus) 		PF00520
(Ion_trans) 		4 ARG A 120
PHE A 116
ILE A 113
PHE A 137
 None
 0.81A 2qeiA-3j9jA:
undetectable		 2qeiA-3j9jA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvd LIPOPROTEIN

(Neisseria
meningitidis) 		PF08794
(Lipoprot_C) 		4 ARG D 195
PHE D 194
ILE D 196
PHE D 222
 None
 1.06A 2qeiA-3kvdD:
undetectable		 2qeiA-3kvdD:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7y PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1108C

(Streptococcus
mutans) 		PF08282
(Hydrolase_3) 		4 ARG A  25
PHE A  26
ILE A  29
PHE A  40
 None
 1.23A 2qeiA-3l7yA:
undetectable		 2qeiA-3l7yA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lzb EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 SER A 888
ARG A 779
PHE A 886
ILE A 785
 None
 1.22A 2qeiA-3lzbA:
1.6		 2qeiA-3lzbA:
19.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		5 SER A 181
ARG A 185
PHE A 194
ILE A 197
PHE A 350
 None
 0.21A 2qeiA-3mpnA:
67.6		 2qeiA-3mpnA:
99.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op6 UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		PF04073
(tRNA_edit) 		4 SER A  19
PHE A 124
ILE A 122
PHE A 102
 None
 1.08A 2qeiA-3op6A:
undetectable		 2qeiA-3op6A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvd CAPSID

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 ARG A 432
PHE A 431
ILE A 234
PHE A 512
 None
 1.25A 2qeiA-3pvdA:
undetectable		 2qeiA-3pvdA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q08 CHLORITE DISMUTASE

(Dechloromonas
aromatica) 		PF06778
(Chlor_dismutase) 		4 ARG A  67
PHE A  75
ILE A 243
PHE A  94
 None
 1.00A 2qeiA-3q08A:
undetectable		 2qeiA-3q08A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qde CELLOBIOSE
PHOSPHORYLASE

(Ruminiclostridium
thermocellum) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 ARG A 629
PHE A 627
ILE A 637
PHE A 584
 None
 1.26A 2qeiA-3qdeA:
0.7		 2qeiA-3qdeA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdn PUTATIVE THIOREDOXIN
PROTEIN

(Salmonella
enterica) 		PF00085
(Thioredoxin)
PF14559
(TPR_19)
PF14561
(TPR_20) 		4 SER A  21
PHE A  28
ILE A   9
PHE A  73
 None
 1.27A 2qeiA-3qdnA:
undetectable		 2qeiA-3qdnA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sim PROTEIN, FAMILY 18
CHITINASE

(Crocus vernus) 		PF00704
(Glyco_hydro_18) 		4 SER A 258
PHE A 219
ILE A 250
PHE A 235
 None
 1.25A 2qeiA-3simA:
undetectable		 2qeiA-3simA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swx PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE

(Mycobacteroides
abscessus) 		PF00378
(ECH_1) 		4 ARG A 149
PHE A 150
ILE A 179
PHE A 169
 None
 1.25A 2qeiA-3swxA:
undetectable		 2qeiA-3swxA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vqr PUTATIVE
OXIDOREDUCTASE

(Aeropyrum
pernix) 		PF01266
(DAO) 		4 SER A  56
ARG A  52
PHE A  54
ILE A 152
 None
 1.14A 2qeiA-3vqrA:
undetectable		 2qeiA-3vqrA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0l CULLIN-4B

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 ARG E 555
PHE E 551
ILE E 552
PHE E 548
 None
 1.15A 2qeiA-4a0lE:
2.7		 2qeiA-4a0lE:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fn7 ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Mycobacterium
tuberculosis) 		PF00378
(ECH_1) 		4 SER A  91
ARG A 211
ARG A 148
ILE A 144
 None
 1.28A 2qeiA-4fn7A:
undetectable		 2qeiA-4fn7A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iil MEMBRANE LIPOPROTEIN
TPN38(B)

(Treponema
pallidum) 		PF02608
(Bmp) 		4 ARG A  76
ARG A 100
ILE A 115
PHE A 117
 None
 1.20A 2qeiA-4iilA:
undetectable		 2qeiA-4iilA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixa RESPONSE REGULATOR
SAER

(Staphylococcus
epidermidis) 		PF00486
(Trans_reg_C) 		4 SER A 167
ARG A 168
PHE A 225
ILE A 215
 None
 1.21A 2qeiA-4ixaA:
undetectable		 2qeiA-4ixaA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j2q S-ARRESTIN

(Bos taurus) 		PF00339
(Arrestin_N)
PF02752
(Arrestin_C) 		4 ARG A  66
PHE A 147
ILE A 174
PHE A 122
 None
 1.26A 2qeiA-4j2qA:
undetectable		 2qeiA-4j2qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jlz UNCHARACTERIZED
PROTEIN

(Sus scrofa) 		PF03281
(Mab-21) 		4 SER A 176
PHE A 255
ILE A 259
PHE A 205
 None
 1.26A 2qeiA-4jlzA:
undetectable		 2qeiA-4jlzA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksf MALONYL-COA
DECARBOXYLASE

(Agrobacterium
vitis) 		PF05292
(MCD)
PF17408
(MCD_N) 		4 ARG A  66
PHE A  67
ILE A  37
PHE A  75
 None
 1.25A 2qeiA-4ksfA:
undetectable		 2qeiA-4ksfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnd TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 18

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 ARG A 271
PHE A  91
ILE A 102
PHE A 122
 None
 1.22A 2qeiA-4nndA:
undetectable		 2qeiA-4nndA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlb PROBABLE GLYCOGEN
[STARCH] SYNTHASE

(Caenorhabditis
elegans) 		PF05693
(Glycogen_syn) 		4 SER A 401
PHE A 325
ILE A 326
PHE A 387
 None
 1.17A 2qeiA-4qlbA:
undetectable		 2qeiA-4qlbA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgk UNCHARACTERIZED
PROTEIN

(Yersinia pestis) 		PF07350
(DUF1479) 		4 SER A 193
ARG A 188
ARG A 186
ILE A 134
 None
 1.28A 2qeiA-4rgkA:
undetectable		 2qeiA-4rgkA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twe N-ACETYLATED-ALPHA-L
INKED ACIDIC
DIPEPTIDASE-LIKE
PROTEIN

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 SER A 523
ARG A 664
PHE A 666
PHE A 628
 None
 1.15A 2qeiA-4tweA:
undetectable		 2qeiA-4tweA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4usq PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE

(Cellvibrio sp.
BR) 		PF13738
(Pyr_redox_3) 		4 SER A  35
PHE A  39
ILE A  18
PHE A 101
 None
 1.26A 2qeiA-4usqA:
undetectable		 2qeiA-4usqA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		4 SER A 120
PHE A 123
ILE A 106
PHE A 108
 None
 1.15A 2qeiA-4zzeA:
undetectable		 2qeiA-4zzeA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awe PUTATIVE ACETOIN
UTILIZATION PROTEIN,
ACETOIN
DEHYDROGENASE

(Thermus
thermophilus) 		PF00571
(CBS) 		4 ARG A  33
ARG A  34
PHE A  32
ILE A 120
 None
 1.25A 2qeiA-5aweA:
undetectable		 2qeiA-5aweA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 ARG A 291
PHE A 477
ILE A 495
PHE A 491
 None
 1.21A 2qeiA-5bnzA:
undetectable		 2qeiA-5bnzA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 SER A 293
PHE A 477
ILE A 495
PHE A 491
 None
 1.03A 2qeiA-5bnzA:
undetectable		 2qeiA-5bnzA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5caw E3 UBIQUITIN-PROTEIN
LIGASE PARKIN

(Pediculus
humanus) 		PF01485
(IBR) 		4 ARG A 258
PHE A 253
ILE A 300
PHE A 266
 SO4  A1009 (-3.2A)
None
None
None
 1.25A 2qeiA-5cawA:
undetectable		 2qeiA-5cawA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do9 REGULATOR OF
G-PROTEIN SIGNALING
8

(Homo sapiens) 		PF00615
(RGS) 		4 SER B  79
ARG B  71
PHE B  70
PHE B  57
 None
 1.22A 2qeiA-5do9B:
2.9		 2qeiA-5do9B:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B

(Neotoma lepida) 		PF00067
(p450) 		4 SER A 160
PHE A 157
ILE A 453
PHE A 171
 None
 1.12A 2qeiA-5e0eA:
undetectable		 2qeiA-5e0eA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9u GLYCOSYLTRANSFERASE-
STABILIZING PROTEIN
GTF2

(Streptococcus
gordonii) 		no annotation 4 SER B  43
ARG B 176
PHE B 179
ILE B 161
 None
 1.16A 2qeiA-5e9uB:
undetectable		 2qeiA-5e9uB:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ek0 CHIMERA OF BACTERIAL
ION TRANSPORT
PROTEIN AND HUMAN
SODIUM CHANNEL
PROTEIN TYPE 9
SUBUNIT ALPHA

(Arcobacter
butzleri;
Homo sapiens) 		PF00520
(Ion_trans) 		4 ARG A1559
PHE A1562
ILE A1555
PHE A1572
 None
 1.20A 2qeiA-5ek0A:
undetectable		 2qeiA-5ek0A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 SER A 495
PHE A 492
ILE A 467
PHE A 371
 None
 1.29A 2qeiA-5ereA:
undetectable		 2qeiA-5ereA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fei DISTAL TUBE PROTEIN

(Bacillus virus
phi29) 		PF16838
(Caud_tail_N) 		4 SER A 126
ARG A 574
PHE A 577
ILE A 573
 None
 1.21A 2qeiA-5feiA:
undetectable		 2qeiA-5feiA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jos CYCLOHEXADIENYL
DEHYDRATASE

(synthetic
construct) 		PF00497
(SBP_bac_3) 		4 ARG A 149
PHE A 147
ILE A 179
PHE A 204
 None
 1.19A 2qeiA-5josA:
undetectable		 2qeiA-5josA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpe SERINE/THREONINE-PRO
TEIN PHOSPHATASE

(Candida
albicans) 		PF00149
(Metallophos)
PF16891
(STPPase_N) 		4 ARG A 208
PHE A 321
ILE A 269
PHE A 301
 None
 1.26A 2qeiA-5jpeA:
undetectable		 2qeiA-5jpeA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1b WD REPEAT-CONTAINING
PROTEIN 48

(Homo sapiens) 		PF00400
(WD40)
PF11816
(DUF3337) 		4 SER B 533
ARG B 527
PHE B 517
ILE B 516
 None
 1.20A 2qeiA-5k1bB:
undetectable		 2qeiA-5k1bB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kca CEREBELLIN-1,CEREBEL
LIN-1,CEREBELLIN-1,G
LUTAMATE RECEPTOR
IONOTROPIC, DELTA-2

(Homo sapiens) 		PF00386
(C1q)
PF01094
(ANF_receptor) 		4 ARG A 715
PHE A 654
ILE A 717
PHE A 670
 None
 0.98A 2qeiA-5kcaA:
undetectable		 2qeiA-5kcaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyo CYP101J2

(Sphingobium
yanoikuyae) 		PF00067
(p450) 		4 ARG A 145
PHE A 144
ILE A 141
PHE A 156
 None
 1.29A 2qeiA-5kyoA:
undetectable		 2qeiA-5kyoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2e GLUTAMATE RECEPTOR
IONOTROPIC,
DELTA-2,GLUTAMATE
RECEPTOR IONOTROPIC,
DELTA-2

(Rattus
norvegicus) 		PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 ARG A 229
PHE A 168
ILE A 231
PHE A 184
 None
 1.03A 2qeiA-5l2eA:
undetectable		 2qeiA-5l2eA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3d LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1A

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 SER A 817
ARG A 820
ARG A 824
ILE A 825
 None
 1.27A 2qeiA-5l3dA:
undetectable		 2qeiA-5l3dA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkm DNA REPAIR PROTEIN
RADA

(Streptococcus
pneumoniae) 		PF13481
(AAA_25)
PF13541
(ChlI) 		4 SER A  89
PHE A 209
ILE A  93
PHE A  77
 None
 1.23A 2qeiA-5lkmA:
undetectable		 2qeiA-5lkmA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgv PHENYLALANINE--TRNA
LIGASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01409
(tRNA-synt_2d)
PF03147
(FDX-ACB) 		4 ARG A 414
PHE A 333
ILE A 331
PHE A 345
 None
 1.27A 2qeiA-5mgvA:
undetectable		 2qeiA-5mgvA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nvr TELOMERE LENGTH
REGULATOR PROTEIN
RIF1

(Saccharomyces
cerevisiae) 		PF12231
(Rif1_N) 		4 SER A 417
ARG A 343
PHE A 381
PHE A 403
 None
 1.08A 2qeiA-5nvrA:
undetectable		 2qeiA-5nvrA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nvr TELOMERE LENGTH
REGULATOR PROTEIN
RIF1

(Saccharomyces
cerevisiae) 		PF12231
(Rif1_N) 		4 SER A 417
PHE A 381
ILE A 377
PHE A 403
 None
 1.27A 2qeiA-5nvrA:
undetectable		 2qeiA-5nvrA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofn DNA PRIMASE SMALL
SUBUNIT PRIS

(Sulfolobus
solfataricus) 		no annotation 4 SER A 256
ARG A 320
ILE A 146
PHE A 269
 None
 1.13A 2qeiA-5ofnA:
undetectable		 2qeiA-5ofnA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM6

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ARG 6 798
PHE 6 709
ILE 6 678
PHE 6 641
 AGS  22001 (-3.6A)
None
None
None
 1.10A 2qeiA-5udb6:
undetectable		 2qeiA-5udb6:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v12 HERCYNYLCYSTEINE
SULFOXIDE LYASE

(Neurospora
crassa) 		no annotation 4 ARG C 201
PHE C 202
ILE C 191
PHE C 130
 None
 1.23A 2qeiA-5v12C:
undetectable		 2qeiA-5v12C:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v2d DIOXYGENASE

(Pseudomonas
brassicacearum) 		no annotation 4 SER A  19
ARG A 469
PHE A 468
ILE A 466
 None
 1.16A 2qeiA-5v2dA:
undetectable		 2qeiA-5v2dA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f DNA REPLICATION
LICENSING FACTOR
MCM7

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ARG 7 687
PHE 7 594
ILE 7 563
PHE 7 526
 AGS  72001 (-2.3A)
None
None
None
 0.99A 2qeiA-5v8f7:
undetectable		 2qeiA-5v8f7:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f ORIGIN RECOGNITION
COMPLEX SUBUNIT 3
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5

(Saccharomyces
cerevisiae) 		PF13401
(AAA_22)
PF14630
(ORC5_C)
no annotation 		4 SER C 254
ARG C 257
PHE E 256
ILE E 255
 None
None
AGS  E2001 (-4.8A)
None
 1.22A 2qeiA-5v8fC:
undetectable		 2qeiA-5v8fC:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vh1 GAMMA S-CRYSTALLIN

(Gallus gallus) 		PF00030
(Crystall) 		4 SER A 174
ARG A 173
PHE A 172
PHE A 108
 None
 1.14A 2qeiA-5vh1A:
undetectable		 2qeiA-5vh1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y30 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 4 SER A  77
PHE A  98
ILE A 122
PHE A 111
 None
 1.22A 2qeiA-5y30A:
undetectable		 2qeiA-5y30A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		4 ARG C  82
ARG C  79
PHE C  78
ILE C  76
 None
 1.10A 2qeiA-5y3rC:
undetectable		 2qeiA-5y3rC:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST2
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1

(Saccharomyces
cerevisiae) 		no annotation 4 SER B 118
PHE G 409
ILE B  47
PHE G 413
 None
 1.25A 2qeiA-6eznB:
undetectable		 2qeiA-6eznB:
9.71