SIMILAR PATTERNS OF AMINO ACIDS FOR 2QEI_A_CXXA801_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bs9 ACETYL XYLAN
ESTERASE


(Talaromyces
purpureogenus)
PF01083
(Cutinase)
5 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
None
1.14A 2qeiA-1bs9A:
undetectable
2qeiA-1bs9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)


(Haemophilus
influenzae)
PF00145
(DNA_methylase)
5 LEU A 142
VAL A 149
GLN A 151
ILE A 316
LEU A  13
None
1.22A 2qeiA-1dctA:
undetectable
2qeiA-1dctA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkp PHYTASE

(Escherichia
coli)
PF00328
(His_Phos_2)
5 LEU A 310
LEU A 314
ILE A 275
PHE A 396
LEU A 279
None
1.21A 2qeiA-1dkpA:
0.0
2qeiA-1dkpA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g6q HNRNP ARGININE
N-METHYLTRANSFERASE


(Saccharomyces
cerevisiae)
PF06325
(PrmA)
5 LEU 1 138
LEU 1 139
ILE 1 168
PHE 1 237
LEU 1 307
None
1.16A 2qeiA-1g6q1:
undetectable
2qeiA-1g6q1:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4l CELL DIVISION
PROTEIN KINASE 5


(Homo sapiens)
PF00069
(Pkinase)
5 LEU A 267
ARG A 274
ILE A 215
LEU A 173
ASP A 171
None
1.19A 2qeiA-1h4lA:
0.8
2qeiA-1h4lA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htj KIAA0380

(Homo sapiens)
PF09128
(RGS-like)
5 LEU F 324
LEU F 317
ARG F 320
PHE F 311
LEU F 436
None
1.00A 2qeiA-1htjF:
0.0
2qeiA-1htjF:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE


(Azotobacter
vinelandii)
PF03971
(IDH)
5 LEU A 663
GLN A 669
ILE A  25
PHE A  29
LEU A 737
None
1.27A 2qeiA-1j1wA:
0.0
2qeiA-1j1wA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qoz ACETYL XYLAN
ESTERASE


(Trichoderma
reesei)
PF01083
(Cutinase)
5 ARG A 155
ILE A 167
PHE A 159
PHE A 130
LEU A 100
None
1.21A 2qeiA-1qozA:
undetectable
2qeiA-1qozA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkt PROTEIN YFIR

(Bacillus
subtilis)
PF00440
(TetR_N)
5 LEU A  75
LEU A 141
ILE A  88
PHE A 134
LEU A 196
None
1.19A 2qeiA-1rktA:
0.6
2qeiA-1rktA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rty YVQK PROTEIN

(Bacillus
subtilis)
PF01923
(Cob_adeno_trans)
5 LEU A  67
VAL A  90
ILE A  33
LEU A  74
ASP A  73
None
1.01A 2qeiA-1rtyA:
undetectable
2qeiA-1rtyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sw6 REGULATORY PROTEIN
SWI6


(Saccharomyces
cerevisiae)
PF00023
(Ank)
PF13857
(Ank_5)
5 LEU A 230
LEU A 453
ILE A 382
LEU A 345
ASP A 220
None
1.23A 2qeiA-1sw6A:
0.0
2qeiA-1sw6A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szs 4-AMINOBUTYRATE
AMINOTRANSFERASE


(Escherichia
coli)
PF00202
(Aminotran_3)
5 LEU A 225
LEU A 228
ARG A 226
ILE A 203
ASP A 262
None
1.01A 2qeiA-1szsA:
undetectable
2qeiA-1szsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9i DNA ENDONUCLEASE
I-CREI


(Chlamydomonas
reinhardtii)
PF00961
(LAGLIDADG_1)
5 LEU A  78
GLN A  44
ILE A  62
PHE A  87
LEU A  13
None
1.18A 2qeiA-1t9iA:
undetectable
2qeiA-1t9iA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG


(Plasmodium
falciparum)
PF00069
(Pkinase)
5 LEU A  54
ILE A  51
PHE A  79
PHE A 150
LEU A  75
None
1.18A 2qeiA-1v0bA:
undetectable
2qeiA-1v0bA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE


(Thermus
thermophilus)
PF00294
(PfkB)
5 LEU A  14
LEU A  90
ARG A  91
VAL A 101
ASP A 287
None
1.23A 2qeiA-1v19A:
undetectable
2qeiA-1v19A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9s URACIL
PHOSPHORIBOSYLTRANSF
ERASE


(Thermus
thermophilus)
PF14681
(UPRTase)
5 LEU A 101
LEU A 141
ILE A  99
LEU A 128
ASP A 130
None
None
None
None
SO4  A 517 ( 4.1A)
1.22A 2qeiA-1v9sA:
undetectable
2qeiA-1v9sA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wni TRIMERELYSIN II

(Protobothrops
flavoviridis)
PF01421
(Reprolysin)
5 LEU A  53
GLN A  35
ILE A  12
LEU A  98
ASP A 128
None
1.27A 2qeiA-1wniA:
undetectable
2qeiA-1wniA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wwp HYPOTHETICAL PROTEIN
TTHA0636


(Thermus
thermophilus)
PF08780
(NTase_sub_bind)
5 LEU A 117
LEU A 114
ARG A 116
GLN A 112
PHE A  37
None
1.26A 2qeiA-1wwpA:
undetectable
2qeiA-1wwpA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xa0 PUTATIVE NADPH
DEPENDENT
OXIDOREDUCTASES


(Geobacillus
stearothermophilus)
PF00107
(ADH_zinc_N)
5 LEU A 141
LEU A 146
ILE A 138
LEU A 291
ASP A 290
None
1.15A 2qeiA-1xa0A:
undetectable
2qeiA-1xa0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yd9 CORE HISTONE
MACRO-H2A.1


(Rattus
norvegicus)
PF01661
(Macro)
5 LEU A  21
LEU A  15
ILE A 155
LEU A 119
ASP A 123
None
1.19A 2qeiA-1yd9A:
undetectable
2qeiA-1yd9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yk3 HYPOTHETICAL PROTEIN
RV1347C/MT1389


(Mycobacterium
tuberculosis)
PF13523
(Acetyltransf_8)
5 LEU A  94
LEU A  45
ARG A  46
LEU A  56
ASP A  52
None
1.20A 2qeiA-1yk3A:
undetectable
2qeiA-1yk3A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bnx DIAPHANOUS PROTEIN
HOMOLOG 1


(Mus musculus)
PF06367
(Drf_FH3)
PF06371
(Drf_GBD)
5 LEU A 147
ARG A 148
ILE A 185
LEU A 189
ASP A 201
None
1.27A 2qeiA-2bnxA:
2.7
2qeiA-2bnxA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2can ORNITHINE
AMINOTRANSFERASE


(Homo sapiens)
PF00202
(Aminotran_3)
5 LEU A 360
LEU A 363
VAL A 367
ILE A 432
LEU A 397
None
1.19A 2qeiA-2canA:
undetectable
2qeiA-2canA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f31 DIAPHANOUS PROTEIN
HOMOLOG 1


(Mus musculus)
PF06367
(Drf_FH3)
PF06371
(Drf_GBD)
5 LEU A 147
ARG A 148
ILE A 185
LEU A 189
ASP A 201
None
1.13A 2qeiA-2f31A:
undetectable
2qeiA-2f31A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ft3 BIGLYCAN

(Bos taurus)
PF01462
(LRRNT)
PF13855
(LRR_8)
5 LEU A 177
LEU A 191
ILE A 179
PHE A 143
LEU A 159
None
1.16A 2qeiA-2ft3A:
undetectable
2qeiA-2ft3A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g37 PROLINE
DEHYDROGENASE/DELTA-
1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE


(Thermus
thermophilus)
PF01619
(Pro_dh)
5 LEU A 162
LEU A 183
ARG A 184
GLN A 252
ILE A 160
None
None
FAD  A2001 (-3.9A)
FAD  A2001 (-4.7A)
None
1.24A 2qeiA-2g37A:
undetectable
2qeiA-2g37A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9b CALBINDIN

(Rattus
norvegicus)
PF13405
(EF-hand_6)
PF13499
(EF-hand_7)
5 LEU A  31
LEU A  39
GLN A  37
ILE A  73
PHE A  61
None
1.26A 2qeiA-2g9bA:
undetectable
2qeiA-2g9bA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5c 1,8-CINEOLE SYNTHASE

(Salvia
fruticosa)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
5 ARG A 325
ILE A  92
PHE A 124
LEU A 272
ASP A 276
BME  A1592 ( 4.0A)
None
None
None
None
0.87A 2qeiA-2j5cA:
undetectable
2qeiA-2j5cA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j85 STIV B116

(Sulfolobus
turreted
icosahedral
virus 1)
PF08960
(DUF1874)
5 LEU A  57
LEU A  61
ILE A  84
PHE A  32
LEU A   6
None
1.05A 2qeiA-2j85A:
undetectable
2qeiA-2j85A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k5c UNCHARACTERIZED
PROTEIN PF0385


(Pyrococcus
furiosus)
PF03966
(Trm112p)
5 LEU A  77
LEU A  94
ILE A  24
PHE A  81
LEU A  28
None
1.22A 2qeiA-2k5cA:
undetectable
2qeiA-2k5cA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uxt PROTEIN SUFI

(Escherichia
coli)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
5 LEU A 233
LEU A 273
GLN A 270
ILE A 186
LEU A 212
None
1.27A 2qeiA-2uxtA:
undetectable
2qeiA-2uxtA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v26 MYOSIN VI

(Sus scrofa)
PF00063
(Myosin_head)
5 LEU A 742
LEU A 744
ILE A 769
PHE A 758
LEU A 714
None
1.03A 2qeiA-2v26A:
2.0
2qeiA-2v26A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v55 RHO-ASSOCIATED
PROTEIN KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
5 LEU A 268
LEU A 272
ILE A 313
PHE A 299
LEU A 297
None
1.22A 2qeiA-2v55A:
undetectable
2qeiA-2v55A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3z PUTATIVE DEACETYLASE

(Streptococcus
mutans)
PF01522
(Polysacc_deac_1)
5 LEU A 290
VAL A 243
ILE A 125
PHE A 113
LEU A 129
None
1.08A 2qeiA-2w3zA:
undetectable
2qeiA-2w3zA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnw ACTIVATED BY
TRANSCRIPTION FACTOR
SSRB


(Salmonella
enterica)
PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C)
5 LEU A 432
ARG A 417
VAL A 414
GLN A 415
ASP A 390
None
1.24A 2qeiA-2wnwA:
undetectable
2qeiA-2wnwA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av6 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1


(Mus musculus)
PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD)
5 LEU A1302
VAL A1309
GLN A1311
ILE A1590
LEU A1154
None
None
None
None
SAM  A   1 (-4.7A)
1.15A 2qeiA-3av6A:
undetectable
2qeiA-3av6A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8p CHAIN LENGTH
DETERMINANT PROTEIN


(Salmonella
enterica)
PF02706
(Wzz)
5 LEU A 130
LEU A 132
VAL A 134
ILE A  96
ASP A 156
None
1.24A 2qeiA-3b8pA:
undetectable
2qeiA-3b8pA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB


(Neisseria
meningitidis)
PF01625
(PMSR)
5 LEU A 309
ARG A 311
ILE A 305
LEU A 263
ASP A 264
None
1.26A 2qeiA-3bqhA:
undetectable
2qeiA-3bqhA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3btu GALACTOSE/LACTOSE
METABOLISM
REGULATORY PROTEIN
GAL80


(Saccharomyces
cerevisiae)
PF01408
(GFO_IDH_MocA)
5 LEU A 368
GLN A 370
ILE A 147
PHE A  47
PHE A 399
None
1.27A 2qeiA-3btuA:
undetectable
2qeiA-3btuA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM


(Homo sapiens)
PF00343
(Phosphorylase)
5 LEU A 425
ARG A 427
ILE A 414
LEU A 474
ASP A 470
None
1.26A 2qeiA-3cemA:
1.8
2qeiA-3cemA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daq DIHYDRODIPICOLINATE
SYNTHASE


(Staphylococcus
aureus)
PF00701
(DHDPS)
5 LEU A 220
ILE A 237
PHE A 234
LEU A 241
ASP A 191
None
1.26A 2qeiA-3daqA:
undetectable
2qeiA-3daqA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gkf ALDOLASE LSRF

(Escherichia
coli)
no annotation 5 LEU O  78
LEU O  54
VAL O  84
ILE O  75
PHE O  56
None
1.27A 2qeiA-3gkfO:
undetectable
2qeiA-3gkfO:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h3j L-LACTATE
DEHYDROGENASE 1


(Staphylococcus
aureus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
5 VAL A 186
GLN A 174
ILE A 272
PHE A 299
LEU A 261
None
0.84A 2qeiA-3h3jA:
undetectable
2qeiA-3h3jA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ial PROLYL-TRNA
SYNTHETASE


(Giardia
intestinalis)
PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1)
5 LEU A 383
ARG A 407
ILE A  55
PHE A  39
ASP A 311
None
1.00A 2qeiA-3ialA:
undetectable
2qeiA-3ialA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ism CG4930

(Drosophila
melanogaster)
PF08785
(Ku_PK_bind)
5 LEU C  39
VAL C  44
GLN C  45
ILE C  27
LEU C  91
None
1.19A 2qeiA-3ismC:
undetectable
2qeiA-3ismC:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j26 CAPSID PROTEIN V20

(Mimivirus-dependent
virus Sputnik)
no annotation 5 LEU A 130
ARG A 132
ILE A 127
PHE A 101
ASP A 349
None
1.25A 2qeiA-3j26A:
undetectable
2qeiA-3j26A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb4 VP3

(Parechovirus B)
PF00073
(Rhv)
5 LEU C 201
VAL C  75
GLN C 224
ILE C 203
PHE C  90
None
1.20A 2qeiA-3jb4C:
undetectable
2qeiA-3jb4C:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k28 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
2


(Bacillus
anthracis)
PF00202
(Aminotran_3)
5 LEU A 223
LEU A 226
ARG A 227
VAL A 229
ASP A 262
None
1.21A 2qeiA-3k28A:
undetectable
2qeiA-3k28A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN


(Bacillus cereus)
PF01923
(Cob_adeno_trans)
5 LEU A  66
VAL A  89
ILE A  33
LEU A  73
ASP A  72
None
1.07A 2qeiA-3ke5A:
1.7
2qeiA-3ke5A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx2 PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43


(Saccharomyces
cerevisiae)
no annotation 5 LEU B 214
LEU B 227
ILE B 212
PHE B 259
LEU B 241
None
1.20A 2qeiA-3kx2B:
undetectable
2qeiA-3kx2B:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mpn TRANSPORTER

(Aquifex
aeolicus)
PF00209
(SNF)
10 LEU A  25
LEU A  29
VAL A  33
GLN A  34
ILE A 111
PHE A 253
PHE A 320
LEU A 400
ASP A 401
ASP A 404
LEU  A 601 (-4.9A)
None
None
None
None
LEU  A 601 (-4.2A)
None
None
None
None
0.33A 2qeiA-3mpnA:
67.6
2qeiA-3mpnA:
99.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwr A RUBISCO-LIKE
PROTEIN


(Paraburkholderia
fungorum)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
5 LEU A  15
LEU A 134
ARG A 133
LEU A 129
ASP A  18
None
0.90A 2qeiA-3nwrA:
undetectable
2qeiA-3nwrA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nx3 ACETYLORNITHINE
AMINOTRANSFERASE


(Campylobacter
jejuni)
PF00202
(Aminotran_3)
5 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
None
1.02A 2qeiA-3nx3A:
undetectable
2qeiA-3nx3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obv PROTEIN DIAPHANOUS
HOMOLOG 1


(Mus musculus)
PF02181
(FH2)
PF06345
(Drf_DAD)
5 LEU E 916
ILE E 861
PHE E1059
ASP E1064
ASP E1067
None
1.24A 2qeiA-3obvE:
undetectable
2qeiA-3obvE:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pta DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1


(Homo sapiens)
PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
5 LEU A1299
VAL A1306
GLN A1308
ILE A1588
LEU A1151
None
None
None
None
SAH  A1601 (-3.6A)
1.11A 2qeiA-3ptaA:
undetectable
2qeiA-3ptaA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pty ARABINOSYLTRANSFERAS
E C


(Mycobacterium
tuberculosis)
PF14896
(Arabino_trans_C)
5 LEU A 744
VAL A 736
LEU A1049
ASP A1052
ASP A1051
None
AFO  A   1 ( 4.9A)
None
None
AFO  A   1 (-4.7A)
1.16A 2qeiA-3ptyA:
undetectable
2qeiA-3ptyA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC


(Abies grandis)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
5 ARG A 370
ILE A 120
PHE A 372
LEU A 549
ASP A 553
None
0.77A 2qeiA-3s9vA:
3.1
2qeiA-3s9vA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
5 LEU A 146
ARG A 273
ILE A  91
ASP A 434
ASP A 463
None
0.99A 2qeiA-3v9eA:
undetectable
2qeiA-3v9eA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
5 LEU A 146
ARG A 273
ILE A  91
ASP A 434
ASP A 463
None
1.23A 2qeiA-3v9eA:
undetectable
2qeiA-3v9eA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsk PENICILLIN-BINDING
PROTEIN 3


(Staphylococcus
aureus)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
5 LEU A 365
GLN A 355
ILE A 241
LEU A 499
ASP A 498
None
1.17A 2qeiA-3vskA:
undetectable
2qeiA-3vskA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x43 O-UREIDO-L-SERINE
SYNTHASE


(Streptomyces
lavendulae)
PF00291
(PALP)
5 LEU A 189
VAL A 235
GLN A 187
ILE A 160
PHE A 172
None
1.15A 2qeiA-3x43A:
undetectable
2qeiA-3x43A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e77 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE


(Yersinia pestis)
PF00202
(Aminotran_3)
5 LEU A 223
LEU A 226
ARG A 224
ILE A 201
ASP A 259
None
1.03A 2qeiA-4e77A:
undetectable
2qeiA-4e77A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eku PROTEIN-TYROSINE
KINASE 2-BETA


(Homo sapiens)
PF00373
(FERM_M)
5 LEU A 176
ILE A 231
PHE A 227
LEU A 210
ASP A 211
None
1.19A 2qeiA-4ekuA:
undetectable
2qeiA-4ekuA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1c NAD-DEPENDENT
PROTEIN DEACYLASE
SIRTUIN-5,
MITOCHONDRIAL


(Homo sapiens)
PF02146
(SIR2)
5 VAL A  54
ILE A 157
PHE A 260
LEU A 232
ASP A 236
None
1.22A 2qeiA-4g1cA:
undetectable
2qeiA-4g1cA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mn8 LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 223
LEU A 247
GLN A 268
LEU A 218
ASP A 220
None
1.25A 2qeiA-4mn8A:
undetectable
2qeiA-4mn8A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE


(Planctopirus
limnophila)
PF12710
(HAD)
5 LEU A 278
VAL A 280
ILE A  39
PHE A  64
LEU A  27
None
1.18A 2qeiA-4ovyA:
undetectable
2qeiA-4ovyA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pju COHESIN SUBUNIT SA-2

(Homo sapiens)
PF08514
(STAG)
5 LEU A 588
LEU A 574
ILE A 522
ASP A 515
ASP A 581
None
1.27A 2qeiA-4pjuA:
undetectable
2qeiA-4pjuA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgk FATTY ALDEHYDE
DEHYDROGENASE


(Homo sapiens)
PF00171
(Aldedh)
5 LEU A  27
LEU A  30
VAL A  34
GLN A  35
ASP A  69
None
1.15A 2qeiA-4qgkA:
2.1
2qeiA-4qgkA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rck HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN


(Aliivibrio
fischeri)
PF00092
(VWA)
5 LEU A  63
LEU A  20
VAL A  22
ILE A  55
ASP A  90
None
1.04A 2qeiA-4rckA:
undetectable
2qeiA-4rckA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rdy PARATHION HYDROLASE

(Vulcanisaeta
moutnovskia)
PF02126
(PTE)
5 LEU A 311
ILE A 169
PHE A 136
LEU A  68
ASP A  67
None
None
None
KCX  A 138 ( 4.2A)
None
1.25A 2qeiA-4rdyA:
undetectable
2qeiA-4rdyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxu PERIPLASMIC
SUGAR-BINDING
PROTEIN


(Chloroflexus
aurantiacus)
PF13407
(Peripla_BP_4)
5 LEU A 220
LEU A 226
ILE A 234
PHE A 193
LEU A 179
None
1.26A 2qeiA-4rxuA:
undetectable
2qeiA-4rxuA:
21.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4us4 TRANSPORTER

(Bacillus
halodurans)
PF00209
(SNF)
6 LEU A  29
ARG A  34
ILE A 111
PHE A 230
ASP A 382
ASP A 385
None
None
None
TRP  A 601 (-4.4A)
None
None
0.85A 2qeiA-4us4A:
40.4
2qeiA-4us4A:
32.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
5 LEU A 826
LEU A 808
ILE A 786
PHE A 807
LEU A 769
None
1.00A 2qeiA-4xmvA:
undetectable
2qeiA-4xmvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zti POLYMERASE COFACTOR
VP35,NUCLEOPROTEIN


(Zaire
ebolavirus)
PF02097
(Filo_VP35)
PF05505
(Ebola_NP)
5 LEU A  77
LEU A  74
ILE A  56
PHE A  66
LEU A 117
None
1.22A 2qeiA-4ztiA:
undetectable
2qeiA-4ztiA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dly PLANTAZOLICIN
METHYLTRANSFERASE
BAML


(Bacillus
velezensis)
PF13847
(Methyltransf_31)
5 VAL A 160
ILE A 127
PHE A  49
LEU A  78
ASP A  66
None
None
None
None
SAH  A 301 ( 4.7A)
1.19A 2qeiA-5dlyA:
undetectable
2qeiA-5dlyA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN


(Lachnoclostridium
phytofermentans)
PF17167
(Glyco_hydro_36)
5 LEU A  52
GLN A 226
ILE A 110
PHE A 238
LEU A 112
None
1.21A 2qeiA-5h42A:
undetectable
2qeiA-5h42A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5m ALPHA-CATENIN-LIKE
PROTEIN HMP-1


(Caenorhabditis
elegans)
PF01044
(Vinculin)
5 LEU A 372
LEU A 376
ARG A 373
ILE A 306
ASP A 277
None
1.17A 2qeiA-5h5mA:
undetectable
2qeiA-5h5mA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jij ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE


(Mycolicibacterium
thermoresistibile)
PF00982
(Glyco_transf_20)
5 LEU A 297
ARG A 296
ILE A 337
LEU A 287
ASP A 285
None
None
None
EDO  A 509 (-4.1A)
None
0.99A 2qeiA-5jijA:
undetectable
2qeiA-5jijA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jij ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE


(Mycolicibacterium
thermoresistibile)
PF00982
(Glyco_transf_20)
5 LEU A 297
ARG A 296
VAL A 295
LEU A 287
ASP A 285
None
None
None
EDO  A 509 (-4.1A)
None
1.22A 2qeiA-5jijA:
undetectable
2qeiA-5jijA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8r PROTOCADHERIN
GAMMA-B3


(Homo sapiens)
PF00028
(Cadherin)
PF08266
(Cadherin_2)
5 LEU A 232
LEU A 271
ILE A 305
PHE A 262
LEU A 277
None
1.12A 2qeiA-5k8rA:
undetectable
2qeiA-5k8rA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lta PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43


(Chaetomium
thermophilum)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind)
5 LEU A 217
LEU A 230
ILE A 215
PHE A 262
LEU A 244
None
1.24A 2qeiA-5ltaA:
undetectable
2qeiA-5ltaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lti HEME DEPENDENT
OXIDATIVE
N-DEMETHYLASE


(Pseudomonas
mendocina)
PF11927
(DUF3445)
5 LEU A 182
LEU A  83
ARG A 183
LEU A  75
ASP A  78
None
1.21A 2qeiA-5ltiA:
undetectable
2qeiA-5ltiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m31 APPR-1-P PROCESSING
DOMAIN PROTEIN


(Thermus
aquaticus)
PF01661
(Macro)
5 LEU A  96
LEU A  99
GLN A 104
ILE A 132
LEU A   2
None
1.23A 2qeiA-5m31A:
undetectable
2qeiA-5m31A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mfb YIII(DQ)4CQI

(synthetic
construct)
PF00514
(Arm)
5 LEU A 175
LEU A 139
ILE A 161
LEU A 146
ASP A 147
None
1.25A 2qeiA-5mfbA:
undetectable
2qeiA-5mfbA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9j MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 10


(Schizosaccharomyces
pombe)
PF09748
(Med10)
5 LEU B  48
LEU B  28
PHE B  25
LEU B  55
ASP B  54
None
1.26A 2qeiA-5n9jB:
undetectable
2qeiA-5n9jB:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opj RHAMNOGALACTURONAN
LYASE


(Bacteroides
thetaiotaomicron)
no annotation 5 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
None
0.93A 2qeiA-5opjA:
0.5
2qeiA-5opjA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szp PROTOCADHERIN GAMMA
B7


(Mus musculus)
PF00028
(Cadherin)
PF08266
(Cadherin_2)
5 LEU A 110
ILE A 200
PHE A 148
LEU A 170
ASP A 116
None
1.13A 2qeiA-5szpA:
undetectable
2qeiA-5szpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thz CURJ

(Moorea
producens)
no annotation 5 LEU B  90
LEU B  87
ILE B  47
LEU B 316
ASP B 315
None
1.13A 2qeiA-5thzB:
undetectable
2qeiA-5thzB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tjt MAJOR CAPSID PROTEIN

(Escherichia
virus T5)
PF05065
(Phage_capsid)
5 LEU A 271
LEU A 275
ARG A 272
VAL A 421
ILE A 255
None
1.26A 2qeiA-5tjtA:
undetectable
2qeiA-5tjtA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7q RHO-ASSOCIATED
PROTEIN KINASE 2


(Homo sapiens)
PF00069
(Pkinase)
5 LEU A 284
LEU A 288
ILE A 329
PHE A 315
LEU A 313
None
1.15A 2qeiA-5u7qA:
undetectable
2qeiA-5u7qA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqh TUDOR AND KH
DOMAIN-CONTAINING
PROTEIN HOMOLOG


(Bombyx mori)
PF00567
(TUDOR)
5 GLN A  19
ILE A 192
PHE A  20
PHE A  16
LEU A 194
None
1.21A 2qeiA-5vqhA:
undetectable
2qeiA-5vqhA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vtm TYPE II SECRETION
SYSTEM PROTEIN J
TYPE II SECRETION
SYSTEM PROTEIN K


(Pseudomonas
aeruginosa)
no annotation 5 LEU W  73
ARG W  70
VAL W  69
LEU X 172
ASP X 168
None
1.16A 2qeiA-5vtmW:
undetectable
2qeiA-5vtmW:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w21 KLOTHO

(Homo sapiens)
no annotation 5 LEU A 398
VAL A 413
ILE A 401
PHE A 367
LEU A 324
None
1.25A 2qeiA-5w21A:
undetectable
2qeiA-5w21A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5f TAIL TUBE PROTEIN
GP19


(Enterobacteria
phage T4 sensu
lato)
PF06841
(Phage_T4_gp19)
5 LEU A 132
LEU A 157
VAL A 137
GLN A  89
ILE A  25
None
1.15A 2qeiA-5w5fA:
undetectable
2qeiA-5w5fA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xdr PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE DHX15


(Homo sapiens)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind)
5 LEU A 259
LEU A 272
ILE A 257
PHE A 304
LEU A 286
None
1.21A 2qeiA-5xdrA:
undetectable
2qeiA-5xdrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3


(Mus musculus)
no annotation 5 LEU A 879
LEU A 864
ILE A 820
PHE A 875
LEU A 829
None
1.22A 2qeiA-6b3yA:
undetectable
2qeiA-6b3yA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7j 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE


(Vibrio cholerae)
no annotation 5 ARG A   5
ILE A  40
PHE A  93
LEU A  13
ASP A  12
None
1.02A 2qeiA-6b7jA:
undetectable
2qeiA-6b7jA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0b TOXIN B

(Clostridioides
difficile)
no annotation 5 LEU A1647
GLN A1620
ILE A1684
PHE A1623
LEU A1566
None
1.19A 2qeiA-6c0bA:
undetectable
2qeiA-6c0bA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d95 -

(-)
no annotation 5 LEU A  96
LEU A  95
ARG A  97
PHE A  60
ASP A 101
None
1.11A 2qeiA-6d95A:
undetectable
2qeiA-6d95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5z UPF0434 FAMILY
PROTEIN


(Haloferax
volcanii)
no annotation 5 LEU C  20
LEU C  35
ARG C  34
ILE C  30
ASP C  23
GOL  C 101 (-4.4A)
GOL  C 101 (-4.8A)
None
None
None
1.15A 2qeiA-6f5zC:
undetectable
2qeiA-6f5zC:
8.84