SIMILAR PATTERNS OF AMINO ACIDS FOR 2QEI_A_CXXA801
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bs9 | ACETYL XYLANESTERASE (Talaromycespurpureogenus) |
PF01083(Cutinase) | 5 | ARG A 155ILE A 167PHE A 159PHE A 130LEU A 100 | None | 1.14A | 2qeiA-1bs9A:undetectable | 2qeiA-1bs9A:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dct | PROTEIN(MODIFICATIONMETHYLASE HAEIII) (Haemophilusinfluenzae) |
PF00145(DNA_methylase) | 5 | LEU A 142VAL A 149GLN A 151ILE A 316LEU A 13 | None | 1.22A | 2qeiA-1dctA:undetectable | 2qeiA-1dctA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dkp | PHYTASE (Escherichiacoli) |
PF00328(His_Phos_2) | 5 | LEU A 310LEU A 314ILE A 275PHE A 396LEU A 279 | None | 1.21A | 2qeiA-1dkpA:0.0 | 2qeiA-1dkpA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g6q | HNRNP ARGININEN-METHYLTRANSFERASE (Saccharomycescerevisiae) |
PF06325(PrmA) | 5 | LEU 1 138LEU 1 139ILE 1 168PHE 1 237LEU 1 307 | None | 1.16A | 2qeiA-1g6q1:undetectable | 2qeiA-1g6q1:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h4l | CELL DIVISIONPROTEIN KINASE 5 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 267ARG A 274ILE A 215LEU A 173ASP A 171 | None | 1.19A | 2qeiA-1h4lA:0.8 | 2qeiA-1h4lA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htj | KIAA0380 (Homo sapiens) |
PF09128(RGS-like) | 5 | LEU F 324LEU F 317ARG F 320PHE F 311LEU F 436 | None | 1.00A | 2qeiA-1htjF:0.0 | 2qeiA-1htjF:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1w | ISOCITRATEDEHYDROGENASE (Azotobactervinelandii) |
PF03971(IDH) | 5 | LEU A 663GLN A 669ILE A 25PHE A 29LEU A 737 | None | 1.27A | 2qeiA-1j1wA:0.0 | 2qeiA-1j1wA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qoz | ACETYL XYLANESTERASE (Trichodermareesei) |
PF01083(Cutinase) | 5 | ARG A 155ILE A 167PHE A 159PHE A 130LEU A 100 | None | 1.21A | 2qeiA-1qozA:undetectable | 2qeiA-1qozA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rkt | PROTEIN YFIR (Bacillussubtilis) |
PF00440(TetR_N) | 5 | LEU A 75LEU A 141ILE A 88PHE A 134LEU A 196 | None | 1.19A | 2qeiA-1rktA:0.6 | 2qeiA-1rktA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rty | YVQK PROTEIN (Bacillussubtilis) |
PF01923(Cob_adeno_trans) | 5 | LEU A 67VAL A 90ILE A 33LEU A 74ASP A 73 | None | 1.01A | 2qeiA-1rtyA:undetectable | 2qeiA-1rtyA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sw6 | REGULATORY PROTEINSWI6 (Saccharomycescerevisiae) |
PF00023(Ank)PF13857(Ank_5) | 5 | LEU A 230LEU A 453ILE A 382LEU A 345ASP A 220 | None | 1.23A | 2qeiA-1sw6A:0.0 | 2qeiA-1sw6A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szs | 4-AMINOBUTYRATEAMINOTRANSFERASE (Escherichiacoli) |
PF00202(Aminotran_3) | 5 | LEU A 225LEU A 228ARG A 226ILE A 203ASP A 262 | None | 1.01A | 2qeiA-1szsA:undetectable | 2qeiA-1szsA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t9i | DNA ENDONUCLEASEI-CREI (Chlamydomonasreinhardtii) |
PF00961(LAGLIDADG_1) | 5 | LEU A 78GLN A 44ILE A 62PHE A 87LEU A 13 | None | 1.18A | 2qeiA-1t9iA:undetectable | 2qeiA-1t9iA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v0b | CELL DIVISIONCONTROL PROTEIN 2HOMOLOG (Plasmodiumfalciparum) |
PF00069(Pkinase) | 5 | LEU A 54ILE A 51PHE A 79PHE A 150LEU A 75 | None | 1.18A | 2qeiA-1v0bA:undetectable | 2qeiA-1v0bA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v19 | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermusthermophilus) |
PF00294(PfkB) | 5 | LEU A 14LEU A 90ARG A 91VAL A 101ASP A 287 | None | 1.23A | 2qeiA-1v19A:undetectable | 2qeiA-1v19A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9s | URACILPHOSPHORIBOSYLTRANSFERASE (Thermusthermophilus) |
PF14681(UPRTase) | 5 | LEU A 101LEU A 141ILE A 99LEU A 128ASP A 130 | NoneNoneNoneNoneSO4 A 517 ( 4.1A) | 1.22A | 2qeiA-1v9sA:undetectable | 2qeiA-1v9sA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wni | TRIMERELYSIN II (Protobothropsflavoviridis) |
PF01421(Reprolysin) | 5 | LEU A 53GLN A 35ILE A 12LEU A 98ASP A 128 | None | 1.27A | 2qeiA-1wniA:undetectable | 2qeiA-1wniA:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wwp | HYPOTHETICAL PROTEINTTHA0636 (Thermusthermophilus) |
PF08780(NTase_sub_bind) | 5 | LEU A 117LEU A 114ARG A 116GLN A 112PHE A 37 | None | 1.26A | 2qeiA-1wwpA:undetectable | 2qeiA-1wwpA:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xa0 | PUTATIVE NADPHDEPENDENTOXIDOREDUCTASES (Geobacillusstearothermophilus) |
PF00107(ADH_zinc_N) | 5 | LEU A 141LEU A 146ILE A 138LEU A 291ASP A 290 | None | 1.15A | 2qeiA-1xa0A:undetectable | 2qeiA-1xa0A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yd9 | CORE HISTONEMACRO-H2A.1 (Rattusnorvegicus) |
PF01661(Macro) | 5 | LEU A 21LEU A 15ILE A 155LEU A 119ASP A 123 | None | 1.19A | 2qeiA-1yd9A:undetectable | 2qeiA-1yd9A:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yk3 | HYPOTHETICAL PROTEINRV1347C/MT1389 (Mycobacteriumtuberculosis) |
PF13523(Acetyltransf_8) | 5 | LEU A 94LEU A 45ARG A 46LEU A 56ASP A 52 | None | 1.20A | 2qeiA-1yk3A:undetectable | 2qeiA-1yk3A:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bnx | DIAPHANOUS PROTEINHOMOLOG 1 (Mus musculus) |
PF06367(Drf_FH3)PF06371(Drf_GBD) | 5 | LEU A 147ARG A 148ILE A 185LEU A 189ASP A 201 | None | 1.27A | 2qeiA-2bnxA:2.7 | 2qeiA-2bnxA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2can | ORNITHINEAMINOTRANSFERASE (Homo sapiens) |
PF00202(Aminotran_3) | 5 | LEU A 360LEU A 363VAL A 367ILE A 432LEU A 397 | None | 1.19A | 2qeiA-2canA:undetectable | 2qeiA-2canA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f31 | DIAPHANOUS PROTEINHOMOLOG 1 (Mus musculus) |
PF06367(Drf_FH3)PF06371(Drf_GBD) | 5 | LEU A 147ARG A 148ILE A 185LEU A 189ASP A 201 | None | 1.13A | 2qeiA-2f31A:undetectable | 2qeiA-2f31A:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ft3 | BIGLYCAN (Bos taurus) |
PF01462(LRRNT)PF13855(LRR_8) | 5 | LEU A 177LEU A 191ILE A 179PHE A 143LEU A 159 | None | 1.16A | 2qeiA-2ft3A:undetectable | 2qeiA-2ft3A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g37 | PROLINEDEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (Thermusthermophilus) |
PF01619(Pro_dh) | 5 | LEU A 162LEU A 183ARG A 184GLN A 252ILE A 160 | NoneNoneFAD A2001 (-3.9A)FAD A2001 (-4.7A)None | 1.24A | 2qeiA-2g37A:undetectable | 2qeiA-2g37A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g9b | CALBINDIN (Rattusnorvegicus) |
PF13405(EF-hand_6)PF13499(EF-hand_7) | 5 | LEU A 31LEU A 39GLN A 37ILE A 73PHE A 61 | None | 1.26A | 2qeiA-2g9bA:undetectable | 2qeiA-2g9bA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j5c | 1,8-CINEOLE SYNTHASE (Salviafruticosa) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | ARG A 325ILE A 92PHE A 124LEU A 272ASP A 276 | BME A1592 ( 4.0A)NoneNoneNoneNone | 0.87A | 2qeiA-2j5cA:undetectable | 2qeiA-2j5cA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j85 | STIV B116 (Sulfolobusturretedicosahedralvirus 1) |
PF08960(DUF1874) | 5 | LEU A 57LEU A 61ILE A 84PHE A 32LEU A 6 | None | 1.05A | 2qeiA-2j85A:undetectable | 2qeiA-2j85A:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k5c | UNCHARACTERIZEDPROTEIN PF0385 (Pyrococcusfuriosus) |
PF03966(Trm112p) | 5 | LEU A 77LEU A 94ILE A 24PHE A 81LEU A 28 | None | 1.22A | 2qeiA-2k5cA:undetectable | 2qeiA-2k5cA:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uxt | PROTEIN SUFI (Escherichiacoli) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 233LEU A 273GLN A 270ILE A 186LEU A 212 | None | 1.27A | 2qeiA-2uxtA:undetectable | 2qeiA-2uxtA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v26 | MYOSIN VI (Sus scrofa) |
PF00063(Myosin_head) | 5 | LEU A 742LEU A 744ILE A 769PHE A 758LEU A 714 | None | 1.03A | 2qeiA-2v26A:2.0 | 2qeiA-2v26A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v55 | RHO-ASSOCIATEDPROTEIN KINASE 1 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 268LEU A 272ILE A 313PHE A 299LEU A 297 | None | 1.22A | 2qeiA-2v55A:undetectable | 2qeiA-2v55A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3z | PUTATIVE DEACETYLASE (Streptococcusmutans) |
PF01522(Polysacc_deac_1) | 5 | LEU A 290VAL A 243ILE A 125PHE A 113LEU A 129 | None | 1.08A | 2qeiA-2w3zA:undetectable | 2qeiA-2w3zA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnw | ACTIVATED BYTRANSCRIPTION FACTORSSRB (Salmonellaenterica) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 5 | LEU A 432ARG A 417VAL A 414GLN A 415ASP A 390 | None | 1.24A | 2qeiA-2wnwA:undetectable | 2qeiA-2wnwA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3av6 | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 5 | LEU A1302VAL A1309GLN A1311ILE A1590LEU A1154 | NoneNoneNoneNoneSAM A 1 (-4.7A) | 1.15A | 2qeiA-3av6A:undetectable | 2qeiA-3av6A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8p | CHAIN LENGTHDETERMINANT PROTEIN (Salmonellaenterica) |
PF02706(Wzz) | 5 | LEU A 130LEU A 132VAL A 134ILE A 96ASP A 156 | None | 1.24A | 2qeiA-3b8pA:undetectable | 2qeiA-3b8pA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqh | PEPTIDE METHIONINESULFOXIDE REDUCTASEMSRA/MSRB (Neisseriameningitidis) |
PF01625(PMSR) | 5 | LEU A 309ARG A 311ILE A 305LEU A 263ASP A 264 | None | 1.26A | 2qeiA-3bqhA:undetectable | 2qeiA-3bqhA:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3btu | GALACTOSE/LACTOSEMETABOLISMREGULATORY PROTEINGAL80 (Saccharomycescerevisiae) |
PF01408(GFO_IDH_MocA) | 5 | LEU A 368GLN A 370ILE A 147PHE A 47PHE A 399 | None | 1.27A | 2qeiA-3btuA:undetectable | 2qeiA-3btuA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 5 | LEU A 425ARG A 427ILE A 414LEU A 474ASP A 470 | None | 1.26A | 2qeiA-3cemA:1.8 | 2qeiA-3cemA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3daq | DIHYDRODIPICOLINATESYNTHASE (Staphylococcusaureus) |
PF00701(DHDPS) | 5 | LEU A 220ILE A 237PHE A 234LEU A 241ASP A 191 | None | 1.26A | 2qeiA-3daqA:undetectable | 2qeiA-3daqA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gkf | ALDOLASE LSRF (Escherichiacoli) |
no annotation | 5 | LEU O 78LEU O 54VAL O 84ILE O 75PHE O 56 | None | 1.27A | 2qeiA-3gkfO:undetectable | 2qeiA-3gkfO:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h3j | L-LACTATEDEHYDROGENASE 1 (Staphylococcusaureus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | VAL A 186GLN A 174ILE A 272PHE A 299LEU A 261 | None | 0.84A | 2qeiA-3h3jA:undetectable | 2qeiA-3h3jA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ial | PROLYL-TRNASYNTHETASE (Giardiaintestinalis) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 5 | LEU A 383ARG A 407ILE A 55PHE A 39ASP A 311 | None | 1.00A | 2qeiA-3ialA:undetectable | 2qeiA-3ialA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ism | CG4930 (Drosophilamelanogaster) |
PF08785(Ku_PK_bind) | 5 | LEU C 39VAL C 44GLN C 45ILE C 27LEU C 91 | None | 1.19A | 2qeiA-3ismC:undetectable | 2qeiA-3ismC:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j26 | CAPSID PROTEIN V20 (Mimivirus-dependentvirus Sputnik) |
no annotation | 5 | LEU A 130ARG A 132ILE A 127PHE A 101ASP A 349 | None | 1.25A | 2qeiA-3j26A:undetectable | 2qeiA-3j26A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb4 | VP3 (Parechovirus B) |
PF00073(Rhv) | 5 | LEU C 201VAL C 75GLN C 224ILE C 203PHE C 90 | None | 1.20A | 2qeiA-3jb4C:undetectable | 2qeiA-3jb4C:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k28 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE2 (Bacillusanthracis) |
PF00202(Aminotran_3) | 5 | LEU A 223LEU A 226ARG A 227VAL A 229ASP A 262 | None | 1.21A | 2qeiA-3k28A:undetectable | 2qeiA-3k28A:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ke5 | HYPOTHETICALCYTOSOLIC PROTEIN (Bacillus cereus) |
PF01923(Cob_adeno_trans) | 5 | LEU A 66VAL A 89ILE A 33LEU A 73ASP A 72 | None | 1.07A | 2qeiA-3ke5A:1.7 | 2qeiA-3ke5A:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kx2 | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE PRP43 (Saccharomycescerevisiae) |
no annotation | 5 | LEU B 214LEU B 227ILE B 212PHE B 259LEU B 241 | None | 1.20A | 2qeiA-3kx2B:undetectable | 2qeiA-3kx2B:21.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mpn | TRANSPORTER (Aquifexaeolicus) |
PF00209(SNF) | 10 | LEU A 25LEU A 29VAL A 33GLN A 34ILE A 111PHE A 253PHE A 320LEU A 400ASP A 401ASP A 404 | LEU A 601 (-4.9A)NoneNoneNoneNoneLEU A 601 (-4.2A)NoneNoneNoneNone | 0.33A | 2qeiA-3mpnA:67.6 | 2qeiA-3mpnA:99.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwr | A RUBISCO-LIKEPROTEIN (Paraburkholderiafungorum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | LEU A 15LEU A 134ARG A 133LEU A 129ASP A 18 | None | 0.90A | 2qeiA-3nwrA:undetectable | 2qeiA-3nwrA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nx3 | ACETYLORNITHINEAMINOTRANSFERASE (Campylobacterjejuni) |
PF00202(Aminotran_3) | 5 | LEU A 205LEU A 208ARG A 206ILE A 183ASP A 242 | None | 1.02A | 2qeiA-3nx3A:undetectable | 2qeiA-3nx3A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obv | PROTEIN DIAPHANOUSHOMOLOG 1 (Mus musculus) |
PF02181(FH2)PF06345(Drf_DAD) | 5 | LEU E 916ILE E 861PHE E1059ASP E1064ASP E1067 | None | 1.24A | 2qeiA-3obvE:undetectable | 2qeiA-3obvE:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pta | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC) | 5 | LEU A1299VAL A1306GLN A1308ILE A1588LEU A1151 | NoneNoneNoneNoneSAH A1601 (-3.6A) | 1.11A | 2qeiA-3ptaA:undetectable | 2qeiA-3ptaA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pty | ARABINOSYLTRANSFERASE C (Mycobacteriumtuberculosis) |
PF14896(Arabino_trans_C) | 5 | LEU A 744VAL A 736LEU A1049ASP A1052ASP A1051 | NoneAFO A 1 ( 4.9A)NoneNoneAFO A 1 (-4.7A) | 1.16A | 2qeiA-3ptyA:undetectable | 2qeiA-3ptyA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9v | ABIETADIENESYNTHASE,CHLOROPLASTIC (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | ARG A 370ILE A 120PHE A 372LEU A 549ASP A 553 | None | 0.77A | 2qeiA-3s9vA:3.1 | 2qeiA-3s9vA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9e | LACCASE (Botrytis aclada) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 146ARG A 273ILE A 91ASP A 434ASP A 463 | None | 0.99A | 2qeiA-3v9eA:undetectable | 2qeiA-3v9eA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9e | LACCASE (Botrytis aclada) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 146ARG A 273ILE A 91ASP A 434ASP A 463 | None | 1.23A | 2qeiA-3v9eA:undetectable | 2qeiA-3v9eA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsk | PENICILLIN-BINDINGPROTEIN 3 (Staphylococcusaureus) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | LEU A 365GLN A 355ILE A 241LEU A 499ASP A 498 | None | 1.17A | 2qeiA-3vskA:undetectable | 2qeiA-3vskA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x43 | O-UREIDO-L-SERINESYNTHASE (Streptomyceslavendulae) |
PF00291(PALP) | 5 | LEU A 189VAL A 235GLN A 187ILE A 160PHE A 172 | None | 1.15A | 2qeiA-3x43A:undetectable | 2qeiA-3x43A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e77 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Yersinia pestis) |
PF00202(Aminotran_3) | 5 | LEU A 223LEU A 226ARG A 224ILE A 201ASP A 259 | None | 1.03A | 2qeiA-4e77A:undetectable | 2qeiA-4e77A:24.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eku | PROTEIN-TYROSINEKINASE 2-BETA (Homo sapiens) |
PF00373(FERM_M) | 5 | LEU A 176ILE A 231PHE A 227LEU A 210ASP A 211 | None | 1.19A | 2qeiA-4ekuA:undetectable | 2qeiA-4ekuA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1c | NAD-DEPENDENTPROTEIN DEACYLASESIRTUIN-5,MITOCHONDRIAL (Homo sapiens) |
PF02146(SIR2) | 5 | VAL A 54ILE A 157PHE A 260LEU A 232ASP A 236 | None | 1.22A | 2qeiA-4g1cA:undetectable | 2qeiA-4g1cA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn8 | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 223LEU A 247GLN A 268LEU A 218ASP A 220 | None | 1.25A | 2qeiA-4mn8A:undetectable | 2qeiA-4mn8A:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovy | HALOACIDDEHALOGENASE DOMAINPROTEIN HYDROLASE (Planctopiruslimnophila) |
PF12710(HAD) | 5 | LEU A 278VAL A 280ILE A 39PHE A 64LEU A 27 | None | 1.18A | 2qeiA-4ovyA:undetectable | 2qeiA-4ovyA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pju | COHESIN SUBUNIT SA-2 (Homo sapiens) |
PF08514(STAG) | 5 | LEU A 588LEU A 574ILE A 522ASP A 515ASP A 581 | None | 1.27A | 2qeiA-4pjuA:undetectable | 2qeiA-4pjuA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgk | FATTY ALDEHYDEDEHYDROGENASE (Homo sapiens) |
PF00171(Aldedh) | 5 | LEU A 27LEU A 30VAL A 34GLN A 35ASP A 69 | None | 1.15A | 2qeiA-4qgkA:2.1 | 2qeiA-4qgkA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rck | HYPOTHETICALMEMBRANE SPANNINGPROTEIN (Aliivibriofischeri) |
PF00092(VWA) | 5 | LEU A 63LEU A 20VAL A 22ILE A 55ASP A 90 | None | 1.04A | 2qeiA-4rckA:undetectable | 2qeiA-4rckA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rdy | PARATHION HYDROLASE (Vulcanisaetamoutnovskia) |
PF02126(PTE) | 5 | LEU A 311ILE A 169PHE A 136LEU A 68ASP A 67 | NoneNoneNoneKCX A 138 ( 4.2A)None | 1.25A | 2qeiA-4rdyA:undetectable | 2qeiA-4rdyA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxu | PERIPLASMICSUGAR-BINDINGPROTEIN (Chloroflexusaurantiacus) |
PF13407(Peripla_BP_4) | 5 | LEU A 220LEU A 226ILE A 234PHE A 193LEU A 179 | None | 1.26A | 2qeiA-4rxuA:undetectable | 2qeiA-4rxuA:21.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4us4 | TRANSPORTER (Bacillushalodurans) |
PF00209(SNF) | 6 | LEU A 29ARG A 34ILE A 111PHE A 230ASP A 382ASP A 385 | NoneNoneNoneTRP A 601 (-4.4A)NoneNone | 0.85A | 2qeiA-4us4A:40.4 | 2qeiA-4us4A:32.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmv | AMINOPEPTIDASE N (Escherichiacoli) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | LEU A 826LEU A 808ILE A 786PHE A 807LEU A 769 | None | 1.00A | 2qeiA-4xmvA:undetectable | 2qeiA-4xmvA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zti | POLYMERASE COFACTORVP35,NUCLEOPROTEIN (Zaireebolavirus) |
PF02097(Filo_VP35)PF05505(Ebola_NP) | 5 | LEU A 77LEU A 74ILE A 56PHE A 66LEU A 117 | None | 1.22A | 2qeiA-4ztiA:undetectable | 2qeiA-4ztiA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dly | PLANTAZOLICINMETHYLTRANSFERASEBAML (Bacillusvelezensis) |
PF13847(Methyltransf_31) | 5 | VAL A 160ILE A 127PHE A 49LEU A 78ASP A 66 | NoneNoneNoneNoneSAH A 301 ( 4.7A) | 1.19A | 2qeiA-5dlyA:undetectable | 2qeiA-5dlyA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 5 | LEU A 52GLN A 226ILE A 110PHE A 238LEU A 112 | None | 1.21A | 2qeiA-5h42A:undetectable | 2qeiA-5h42A:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5m | ALPHA-CATENIN-LIKEPROTEIN HMP-1 (Caenorhabditiselegans) |
PF01044(Vinculin) | 5 | LEU A 372LEU A 376ARG A 373ILE A 306ASP A 277 | None | 1.17A | 2qeiA-5h5mA:undetectable | 2qeiA-5h5mA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jij | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (Mycolicibacteriumthermoresistibile) |
PF00982(Glyco_transf_20) | 5 | LEU A 297ARG A 296ILE A 337LEU A 287ASP A 285 | NoneNoneNoneEDO A 509 (-4.1A)None | 0.99A | 2qeiA-5jijA:undetectable | 2qeiA-5jijA:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jij | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (Mycolicibacteriumthermoresistibile) |
PF00982(Glyco_transf_20) | 5 | LEU A 297ARG A 296VAL A 295LEU A 287ASP A 285 | NoneNoneNoneEDO A 509 (-4.1A)None | 1.22A | 2qeiA-5jijA:undetectable | 2qeiA-5jijA:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8r | PROTOCADHERINGAMMA-B3 (Homo sapiens) |
PF00028(Cadherin)PF08266(Cadherin_2) | 5 | LEU A 232LEU A 271ILE A 305PHE A 262LEU A 277 | None | 1.12A | 2qeiA-5k8rA:undetectable | 2qeiA-5k8rA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lta | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE PRP43 (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | LEU A 217LEU A 230ILE A 215PHE A 262LEU A 244 | None | 1.24A | 2qeiA-5ltaA:undetectable | 2qeiA-5ltaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lti | HEME DEPENDENTOXIDATIVEN-DEMETHYLASE (Pseudomonasmendocina) |
PF11927(DUF3445) | 5 | LEU A 182LEU A 83ARG A 183LEU A 75ASP A 78 | None | 1.21A | 2qeiA-5ltiA:undetectable | 2qeiA-5ltiA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m31 | APPR-1-P PROCESSINGDOMAIN PROTEIN (Thermusaquaticus) |
PF01661(Macro) | 5 | LEU A 96LEU A 99GLN A 104ILE A 132LEU A 2 | None | 1.23A | 2qeiA-5m31A:undetectable | 2qeiA-5m31A:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mfb | YIII(DQ)4CQI (syntheticconstruct) |
PF00514(Arm) | 5 | LEU A 175LEU A 139ILE A 161LEU A 146ASP A 147 | None | 1.25A | 2qeiA-5mfbA:undetectable | 2qeiA-5mfbA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9j | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 10 (Schizosaccharomycespombe) |
PF09748(Med10) | 5 | LEU B 48LEU B 28PHE B 25LEU B 55ASP B 54 | None | 1.26A | 2qeiA-5n9jB:undetectable | 2qeiA-5n9jB:15.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opj | RHAMNOGALACTURONANLYASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | LEU A 205GLN A 211ILE A 146PHE A 244LEU A 158 | None | 0.93A | 2qeiA-5opjA:0.5 | 2qeiA-5opjA:8.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szp | PROTOCADHERIN GAMMAB7 (Mus musculus) |
PF00028(Cadherin)PF08266(Cadherin_2) | 5 | LEU A 110ILE A 200PHE A 148LEU A 170ASP A 116 | None | 1.13A | 2qeiA-5szpA:undetectable | 2qeiA-5szpA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thz | CURJ (Mooreaproducens) |
no annotation | 5 | LEU B 90LEU B 87ILE B 47LEU B 316ASP B 315 | None | 1.13A | 2qeiA-5thzB:undetectable | 2qeiA-5thzB:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tjt | MAJOR CAPSID PROTEIN (Escherichiavirus T5) |
PF05065(Phage_capsid) | 5 | LEU A 271LEU A 275ARG A 272VAL A 421ILE A 255 | None | 1.26A | 2qeiA-5tjtA:undetectable | 2qeiA-5tjtA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7q | RHO-ASSOCIATEDPROTEIN KINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 284LEU A 288ILE A 329PHE A 315LEU A 313 | None | 1.15A | 2qeiA-5u7qA:undetectable | 2qeiA-5u7qA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vqh | TUDOR AND KHDOMAIN-CONTAININGPROTEIN HOMOLOG (Bombyx mori) |
PF00567(TUDOR) | 5 | GLN A 19ILE A 192PHE A 20PHE A 16LEU A 194 | None | 1.21A | 2qeiA-5vqhA:undetectable | 2qeiA-5vqhA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vtm | TYPE II SECRETIONSYSTEM PROTEIN JTYPE II SECRETIONSYSTEM PROTEIN K (Pseudomonasaeruginosa) |
no annotation | 5 | LEU W 73ARG W 70VAL W 69LEU X 172ASP X 168 | None | 1.16A | 2qeiA-5vtmW:undetectable | 2qeiA-5vtmW:8.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w21 | KLOTHO (Homo sapiens) |
no annotation | 5 | LEU A 398VAL A 413ILE A 401PHE A 367LEU A 324 | None | 1.25A | 2qeiA-5w21A:undetectable | 2qeiA-5w21A:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w5f | TAIL TUBE PROTEINGP19 (Enterobacteriaphage T4 sensulato) |
PF06841(Phage_T4_gp19) | 5 | LEU A 132LEU A 157VAL A 137GLN A 89ILE A 25 | None | 1.15A | 2qeiA-5w5fA:undetectable | 2qeiA-5w5fA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xdr | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE DHX15 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | LEU A 259LEU A 272ILE A 257PHE A 304LEU A 286 | None | 1.21A | 2qeiA-5xdrA:undetectable | 2qeiA-5xdrA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3y | DENNDOMAIN-CONTAININGPROTEIN 3 (Mus musculus) |
no annotation | 5 | LEU A 879LEU A 864ILE A 820PHE A 875LEU A 829 | None | 1.22A | 2qeiA-6b3yA:undetectable | 2qeiA-6b3yA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b7j | 3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN]DEHYDRATASE (Vibrio cholerae) |
no annotation | 5 | ARG A 5ILE A 40PHE A 93LEU A 13ASP A 12 | None | 1.02A | 2qeiA-6b7jA:undetectable | 2qeiA-6b7jA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0b | TOXIN B (Clostridioidesdifficile) |
no annotation | 5 | LEU A1647GLN A1620ILE A1684PHE A1623LEU A1566 | None | 1.19A | 2qeiA-6c0bA:undetectable | 2qeiA-6c0bA:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | LEU A 96LEU A 95ARG A 97PHE A 60ASP A 101 | None | 1.11A | 2qeiA-6d95A:undetectable | 2qeiA-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5z | UPF0434 FAMILYPROTEIN (Haloferaxvolcanii) |
no annotation | 5 | LEU C 20LEU C 35ARG C 34ILE C 30ASP C 23 | GOL C 101 (-4.4A)GOL C 101 (-4.8A)NoneNoneNone | 1.15A | 2qeiA-6f5zC:undetectable | 2qeiA-6f5zC:8.84 |