SIMILAR PATTERNS OF AMINO ACIDS FOR 2QD5_B_CHDB1104

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1epv ALANINE RACEMASE

(Geobacillus
stearothermophilus) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		3 LEU A 319
PRO A 320
LEU A 323
 None
 0.49A 2qd5B-1epvA:
undetectable		 2qd5B-1epvA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evj GLUCOSE-FRUCTOSE
OXIDOREDUCTASE

(Zymomonas
mobilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 LEU A 106
PRO A 107
LEU A 110
 NAD  A 500 (-3.9A)
NAD  A 500 (-4.5A)
None
 0.44A 2qd5B-1evjA:
3.9		 2qd5B-1evjA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE

(Neisseria
meningitidis) 		PF02348
(CTP_transf_3) 		3 LEU A 168
PRO A 169
LEU A 141
 None
 0.49A 2qd5B-1eziA:
2.8		 2qd5B-1eziA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0v PROTEINASE A

(Saccharomyces
cerevisiae) 		PF00026
(Asp) 		3 LEU A 223
PRO A 224
LEU A 227
 None
 0.42A 2qd5B-1g0vA:
undetectable		 2qd5B-1g0vA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwi CYTOCHROME P450
154C1

(Streptomyces
coelicolor) 		PF00067
(p450) 		3 LEU A  37
PRO A  38
LEU A  82
 None
 0.47A 2qd5B-1gwiA:
undetectable		 2qd5B-1gwiA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h29 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C

(Desulfovibrio
vulgaris) 		PF02085
(Cytochrom_CIII) 		3 LEU A 276
PRO A 277
LEU A 399
 None
HEC  A1112 (-3.7A)
None
 0.46A 2qd5B-1h29A:
undetectable		 2qd5B-1h29A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE

(Zymomonas
mobilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 LEU A 158
PRO A 159
LEU A 162
 NDP  A 500 (-4.1A)
NDP  A 500 (-4.1A)
None
 0.44A 2qd5B-1h6dA:
2.6		 2qd5B-1h6dA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1klq MITOTIC SPINDLE
ASSEMBLY CHECKPOINT
PROTEIN MAD2A

(Homo sapiens) 		PF02301
(HORMA) 		3 LEU A 144
PRO A 145
LEU A 147
 None
 0.49A 2qd5B-1klqA:
undetectable		 2qd5B-1klqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lln ANTIVIRAL PROTEIN 3

(Phytolacca
americana) 		PF00161
(RIP) 		3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.32A 2qd5B-1llnA:
undetectable		 2qd5B-1llnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obg PHOSPHORIBOSYLAMIDOI
MIDAZOLE-
SUCCINOCARBOXAMIDE
SYNTHASE

(Saccharomyces
cerevisiae) 		PF01259
(SAICAR_synt) 		3 LEU A  89
PRO A  90
LEU A  93
 None
 0.44A 2qd5B-1obgA:
undetectable		 2qd5B-1obgA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1or7 RNA POLYMERASE
SIGMA-E FACTOR

(Escherichia
coli) 		PF04542
(Sigma70_r2)
PF08281
(Sigma70_r4_2) 		3 LEU A 138
PRO A 139
LEU A 142
 None
 0.49A 2qd5B-1or7A:
undetectable		 2qd5B-1or7A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p2z HEXON PROTEIN

(Human
mastadenovirus
C) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 LEU A 496
PRO A 497
LEU A 500
 None
 0.49A 2qd5B-1p2zA:
undetectable		 2qd5B-1p2zA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qas PHOSPHOLIPASE C
DELTA-1

(Rattus
norvegicus) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU A 425
PRO A 426
LEU A 302
 None
 0.27A 2qd5B-1qasA:
3.5		 2qd5B-1qasA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s1f PUTATIVE CYTOCHROME
P450

(Streptomyces
coelicolor) 		PF00067
(p450) 		3 LEU A  44
PRO A  45
LEU A  82
 None
 0.51A 2qd5B-1s1fA:
undetectable		 2qd5B-1s1fA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us7 HSP90 CO-CHAPERONE
CDC37

(Homo sapiens) 		PF08564
(CDC37_C)
PF08565
(CDC37_M) 		3 LEU B 301
PRO B 302
LEU B 305
 None
 0.31A 2qd5B-1us7B:
undetectable		 2qd5B-1us7B:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vef ACETYLORNITHINE/ACET
YL-LYSINE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00202
(Aminotran_3) 		3 LEU A 100
PRO A 101
LEU A 104
 None
 0.44A 2qd5B-1vefA:
2.3		 2qd5B-1vefA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqr HYPOTHETICAL PROTEIN
CJ0248

(Campylobacter
jejuni) 		PF08668
(HDOD) 		3 LEU A  16
PRO A  17
LEU A  51
 None
 0.40A 2qd5B-1vqrA:
undetectable		 2qd5B-1vqrA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wju NEDD8 ULTIMATE
BUSTER-1

(Homo sapiens) 		no annotation 3 LEU A  22
PRO A  23
LEU A  26
 None
 0.29A 2qd5B-1wjuA:
undetectable		 2qd5B-1wjuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wp9 ATP-DEPENDENT RNA
HELICASE, PUTATIVE

(Pyrococcus
furiosus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 LEU A  30
PRO A  31
LEU A  34
 PO4  A 495 ( 4.7A)
None
None
 0.36A 2qd5B-1wp9A:
3.2		 2qd5B-1wp9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydw AX110P-LIKE PROTEIN

(Arabidopsis
thaliana) 		PF01408
(GFO_IDH_MocA) 		3 LEU A 204
PRO A 205
LEU A 359
 None
 0.48A 2qd5B-1ydwA:
2.7		 2qd5B-1ydwA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zh8 OXIDOREDUCTASE

(Thermotoga
maritima) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 LEU A  78
PRO A  79
LEU A  82
 NAP  A 400 (-4.7A)
NAP  A 400 (-4.5A)
NAP  A 400 (-4.7A)
 0.38A 2qd5B-1zh8A:
2.6		 2qd5B-1zh8A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlp PETAL DEATH PROTEIN

(Dianthus
caryophyllus) 		PF13714
(PEP_mutase) 		3 LEU A  77
PRO A  78
LEU A  82
 None
 0.47A 2qd5B-1zlpA:
undetectable		 2qd5B-1zlpA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a33 HYPOTHETICAL PROTEIN

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		3 LEU A 116
PRO A 117
LEU A  57
 None
 0.30A 2qd5B-2a33A:
undetectable		 2qd5B-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3k PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 7,
ISOFORM 1

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 LEU A 129
PRO A 130
LEU A 114
 None
 0.33A 2qd5B-2a3kA:
undetectable		 2qd5B-2a3kA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 LEU A 834
PRO A 835
LEU A 928
 None
 0.49A 2qd5B-2b39A:
undetectable		 2qd5B-2b39A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5i CYTOKINE RECEPTOR
COMMON GAMMA CHAIN

(Homo sapiens) 		PF00041
(fn3)
PF09240
(IL6Ra-bind) 		3 LEU C  35
PRO C  36
LEU C 110
 None
 0.37A 2qd5B-2b5iC:
undetectable		 2qd5B-2b5iC:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE

(Mycobacterium
tuberculosis) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		3 LEU A 100
PRO A 101
LEU A 104
 None
 0.46A 2qd5B-2c2yA:
2.3		 2qd5B-2c2yA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkh 3-HYDROXYBENZOATE
HYDROXYLASE

(Comamonas
testosteroni) 		PF01494
(FAD_binding_3)
PF07976
(Phe_hydrox_dim) 		3 LEU A 564
PRO A 565
LEU A 568
 None
 0.49A 2qd5B-2dkhA:
undetectable		 2qd5B-2dkhA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C

(Desulfovibrio
vulgaris) 		PF02085
(Cytochrom_CIII) 		3 LEU A 281
PRO A 282
LEU A 410
 None
HEM  A1312 (-3.3A)
None
 0.49A 2qd5B-2e84A:
undetectable		 2qd5B-2e84A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erj CYTOKINE RECEPTOR
COMMON GAMMA CHAIN

(Homo sapiens) 		PF00041
(fn3)
PF09240
(IL6Ra-bind) 		3 LEU C  35
PRO C  36
LEU C 110
 None
 0.40A 2qd5B-2erjC:
undetectable		 2qd5B-2erjC:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		3 LEU A 212
PRO A 213
LEU A  92
 None
 0.49A 2qd5B-2eyqA:
3.5		 2qd5B-2eyqA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv9 DNA POLYMERASE

(Human
alphaherpesvirus
1) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 LEU A1003
PRO A1004
LEU A1007
 None
 0.50A 2qd5B-2gv9A:
undetectable		 2qd5B-2gv9A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h31 MULTIFUNCTIONAL
PROTEIN ADE2

(Homo sapiens) 		PF00731
(AIRC)
PF01259
(SAICAR_synt) 		3 LEU A 368
PRO A 369
LEU A 372
 None
 0.42A 2qd5B-2h31A:
4.5		 2qd5B-2h31A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2idg HYPOTHETICAL PROTEIN
AF0160

(Archaeoglobus
fulgidus) 		PF02613
(Nitrate_red_del) 		3 LEU A 139
PRO A 140
LEU A 145
 None
 0.48A 2qd5B-2idgA:
undetectable		 2qd5B-2idgA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgv TAGATOSE-6-PHOSPHATE
KINASE

(Staphylococcus
aureus) 		PF00294
(PfkB) 		3 LEU A 137
PRO A 138
LEU A 141
 None
 0.50A 2qd5B-2jgvA:
3.1		 2qd5B-2jgvA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jm4 RELAXIN RECEPTOR 1

(Homo sapiens) 		PF00057
(Ldl_recept_a) 		3 LEU A  21
PRO A  22
LEU A  25
 None
 0.50A 2qd5B-2jm4A:
undetectable		 2qd5B-2jm4A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jss CHIMERA OF HISTONE
H2B.1 AND HISTONE
H2A.Z

(Saccharomyces
cerevisiae) 		PF00125
(Histone)
PF16211
(Histone_H2A_C) 		3 LEU A  70
PRO A  71
LEU A  74
 None
 0.46A 2qd5B-2jssA:
undetectable		 2qd5B-2jssA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2np5 TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii) 		PF00440
(TetR_N)
PF13977
(TetR_C_6) 		3 LEU A  93
PRO A  94
LEU A 176
 None
 0.34A 2qd5B-2np5A:
undetectable		 2qd5B-2np5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		3 LEU A 123
PRO A 124
LEU A 168
 None
 0.47A 2qd5B-2o2zA:
3.1		 2qd5B-2o2zA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppg PUTATIVE ISOMERASE

(Sinorhizobium
meliloti) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU A 161
PRO A 162
LEU A 172
 None
 0.47A 2qd5B-2ppgA:
undetectable		 2qd5B-2ppgA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ps2 PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Aspergillus
oryzae) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU A 213
PRO A 214
LEU A 217
 None
 0.46A 2qd5B-2ps2A:
3.6		 2qd5B-2ps2A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		3 LEU A 112
PRO A 113
LEU A  53
 None
 0.50A 2qd5B-2q4dA:
undetectable		 2qd5B-2q4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 LEU D 604
PRO D 605
LEU D 608
 None
 0.49A 2qd5B-2vnuD:
undetectable		 2qd5B-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrk ALPHA-L-ARABINOFURAN
OSIDASE

(Thermobacillus
xylanilyticus) 		PF06964
(Alpha-L-AF_C) 		3 LEU A 399
PRO A 400
LEU A 421
 None
 0.28A 2qd5B-2vrkA:
undetectable		 2qd5B-2vrkA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vzw PROBABLE HISTIDINE
KINASE RESPONSE
REGULATOR

(Mycobacterium
tuberculosis) 		PF13185
(GAF_2) 		3 LEU A 112
PRO A 113
LEU A  93
 ACT  A1207 ( 4.6A)
HEM  A1206 ( 3.7A)
ACT  A1207 (-3.3A)
 0.44A 2qd5B-2vzwA:
undetectable		 2qd5B-2vzwA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		3 LEU A 374
PRO A 375
LEU A   9
 None
 0.36A 2qd5B-2xdqA:
2.7		 2qd5B-2xdqA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyd ANGIOTENSIN-CONVERTI
NG ENZYME

(Homo sapiens) 		PF01401
(Peptidase_M2) 		3 LEU A 375
PRO A 376
LEU A 379
 None
 0.47A 2qd5B-2xydA:
undetectable		 2qd5B-2xydA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yys PROLINE
IMINOPEPTIDASE-RELAT
ED PROTEIN

(Thermus
thermophilus) 		PF12697
(Abhydrolase_6) 		3 LEU A  69
PRO A  70
LEU A  75
 None
 0.29A 2qd5B-2yysA:
1.9		 2qd5B-2yysA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzg ALANYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		3 LEU A 722
PRO A 723
LEU A 727
 None
 0.35A 2qd5B-2zzgA:
undetectable		 2qd5B-2zzgA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3abi PUTATIVE
UNCHARACTERIZED
PROTEIN PH1688

(Pyrococcus
horikoshii) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		3 LEU A  69
PRO A  70
LEU A  73
 NAD  A1001 (-4.8A)
NAD  A1001 (-3.8A)
NAD  A1001 (-4.7A)
 0.50A 2qd5B-3abiA:
3.2		 2qd5B-3abiA:
24.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.47A 2qd5B-3aqiA:
53.6		 2qd5B-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av6 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 LEU A1442
PRO A1443
LEU A1497
 None
 0.41A 2qd5B-3av6A:
undetectable		 2qd5B-3av6A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bba INTERPAIN A

(Prevotella
intermedia) 		PF01640
(Peptidase_C10) 		3 LEU A 142
PRO A 143
LEU A 150
 None
 0.50A 2qd5B-3bbaA:
undetectable		 2qd5B-3bbaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxj RAS
GTPASE-ACTIVATING
PROTEIN SYNGAP

(Rattus
norvegicus) 		PF00168
(C2)
PF00616
(RasGAP) 		3 LEU A 397
PRO A 398
LEU A 401
 None
 0.43A 2qd5B-3bxjA:
undetectable		 2qd5B-3bxjA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT

(Methanosarcina
barkeri) 		PF03063
(Prismane) 		3 LEU A 756
PRO A 757
LEU A 764
 None
 0.42A 2qd5B-3cf4A:
2.7		 2qd5B-3cf4A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfi PSEUDOAGLYCONE
DEACETYLASE DBV21

(Actinoplanes
teichomyceticus) 		PF02585
(PIG-L) 		3 LEU A 197
PRO A 198
LEU A 201
 None
 0.46A 2qd5B-3dfiA:
2.8		 2qd5B-3dfiA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1u ADENOSYLHOMOCYSTEINA
SE

(Leishmania
major) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		3 LEU A 391
PRO A 392
LEU A 395
 None
 0.44A 2qd5B-3g1uA:
4.2		 2qd5B-3g1uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM

(Serratia
plymuthica) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 LEU A 533
PRO A 534
LEU A 537
 None
 0.44A 2qd5B-3gbdA:
undetectable		 2qd5B-3gbdA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmj FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00109
(ketoacyl-synt)
PF01648
(ACPS)
PF02801
(Ketoacyl-synt_C) 		3 LEU A 824
PRO A 825
LEU A 846
 None
 0.37A 2qd5B-3hmjA:
undetectable		 2qd5B-3hmjA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvn HEMOLYSIN

(Streptococcus
suis) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		3 LEU A 130
PRO A 131
LEU A 133
 None
 0.47A 2qd5B-3hvnA:
undetectable		 2qd5B-3hvnA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kio RIBONUCLEASE H2
SUBUNIT B

(Mus musculus) 		PF09468
(RNase_H2-Ydr279) 		3 LEU B  19
PRO B  20
LEU B  23
 None
 0.46A 2qd5B-3kioB:
undetectable		 2qd5B-3kioB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kwl UNCHARACTERIZED
PROTEIN

(Helicobacter
pylori) 		no annotation 3 LEU A 268
PRO A 269
LEU A 296
 None
 0.49A 2qd5B-3kwlA:
2.4		 2qd5B-3kwlA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7n PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
mutans) 		PF00117
(GATase) 		3 LEU A  39
PRO A  40
LEU A  76
 None
 0.36A 2qd5B-3l7nA:
undetectable		 2qd5B-3l7nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m3p GLUTAMINE AMIDO
TRANSFERASE

(Methylobacillus
flagellatus) 		PF00117
(GATase) 		3 LEU A  42
PRO A  43
LEU A  74
 None
 0.50A 2qd5B-3m3pA:
undetectable		 2qd5B-3m3pA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps9 TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC

(Escherichia
coli) 		PF01266
(DAO)
PF05430
(Methyltransf_30) 		3 LEU A 574
PRO A 575
LEU A 649
 None
 0.50A 2qd5B-3ps9A:
undetectable		 2qd5B-3ps9A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pty ARABINOSYLTRANSFERAS
E C

(Mycobacterium
tuberculosis) 		PF14896
(Arabino_trans_C) 		3 LEU A 839
PRO A 840
LEU A 843
 None
 0.39A 2qd5B-3ptyA:
undetectable		 2qd5B-3ptyA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)

(Doryteuthis
pealeii) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU A 456
PRO A 457
LEU A 329
 None
 0.49A 2qd5B-3qr1A:
3.2		 2qd5B-3qr1A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rp7 FLAVOPROTEIN
MONOOXYGENASE

(Klebsiella
pneumoniae) 		PF01494
(FAD_binding_3) 		3 LEU A 223
PRO A 224
LEU A 227
 None
 0.48A 2qd5B-3rp7A:
undetectable		 2qd5B-3rp7A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3siu U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP31

(Homo sapiens) 		PF01798
(Nop) 		3 LEU B 283
PRO B 284
LEU B 287
 None
 0.41A 2qd5B-3siuB:
undetectable		 2qd5B-3siuB:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wa1 BINB PROTEIN

(Lysinibacillus
sphaericus) 		PF05431
(Toxin_10) 		3 LEU A 204
PRO A 205
LEU A  30
 None
 0.49A 2qd5B-3wa1A:
undetectable		 2qd5B-3wa1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2

(Bacillus
halodurans) 		PF02096
(60KD_IMP) 		3 LEU A 236
PRO A 237
LEU A 240
 None
 0.47A 2qd5B-3wo6A:
undetectable		 2qd5B-3wo6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrt BETA-LACTAMASE

(Chromohalobacter
sp. 560) 		PF00144
(Beta-lactamase) 		3 LEU A 118
PRO A 119
LEU A 154
 None
 0.42A 2qd5B-3wrtA:
undetectable		 2qd5B-3wrtA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zif HEXON PROTEIN

(Bovine
mastadenovirus
B) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 LEU A 443
PRO A 444
LEU A 447
 None
 0.47A 2qd5B-3zifA:
undetectable		 2qd5B-3zifA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a26 PUTATIVE
C-1-TETRAHYDROFOLATE
SYNTHASE,
CYTOPLASMIC

(Leishmania
major) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		3 LEU A 103
PRO A 104
LEU A 107
 None
 0.42A 2qd5B-4a26A:
3.0		 2qd5B-4a26A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5o BIFUNCTIONAL PROTEIN
FOLD

(Pseudomonas
aeruginosa) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		3 LEU A 101
PRO A 102
LEU A 105
 None
 0.50A 2qd5B-4a5oA:
2.9		 2qd5B-4a5oA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akr F-ACTIN-CAPPING
PROTEIN SUBUNIT
ALPHA

(Dictyostelium
discoideum) 		PF01267
(F-actin_cap_A) 		3 LEU A  34
PRO A  35
LEU A  39
 None
 0.48A 2qd5B-4akrA:
undetectable		 2qd5B-4akrA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b56 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 1

(Mus musculus) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		3 LEU A 477
PRO A 478
LEU A 481
 None
 0.50A 2qd5B-4b56A:
undetectable		 2qd5B-4b56A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cyj PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3-LIKE PROTEIN

(Chaetomium
thermophilum) 		no annotation 3 LEU A 244
PRO A 245
LEU A 253
 None
 0.36A 2qd5B-4cyjA:
undetectable		 2qd5B-4cyjA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d25 BMVLG PROTEIN

(Bombyx mori) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 LEU A 508
PRO A 509
LEU A 543
 None
 0.47A 2qd5B-4d25A:
3.4		 2qd5B-4d25A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4flx DNA POLYMERASE 1

(Pyrococcus
abyssi) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 LEU A 571
PRO A 572
LEU A 575
 LEU  A 571 ( 0.5A)
PRO  A 572 ( 1.1A)
LEU  A 575 ( 0.6A)
 0.47A 2qd5B-4flxA:
undetectable		 2qd5B-4flxA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB

(Acinetobacter
baumannii) 		PF01636
(APH) 		3 LEU A  81
PRO A  82
LEU A  72
 None
0J9  A 302 (-4.5A)
None
 0.39A 2qd5B-4gkhA:
undetectable		 2qd5B-4gkhA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i6m ACTIN-RELATED
PROTEIN 7

(Saccharomyces
cerevisiae) 		PF00022
(Actin) 		3 LEU A 446
PRO A 447
LEU A 451
 None
 0.31A 2qd5B-4i6mA:
2.6		 2qd5B-4i6mA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		3 LEU A 555
PRO A 556
LEU A 515
 None
 0.38A 2qd5B-4iglA:
undetectable		 2qd5B-4iglA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		3 LEU A 669
PRO A 670
LEU A 977
 None
 0.49A 2qd5B-4iugA:
undetectable		 2qd5B-4iugA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j2g KLTH0A00704P

(Lachancea
thermotolerans) 		PF10033
(ATG13) 		3 LEU A 225
PRO A 226
LEU A 229
 None
 0.50A 2qd5B-4j2gA:
undetectable		 2qd5B-4j2gA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk7 ESX-1 SECRETION
SYSTEM PROTEIN ECCB1

(Mycobacterium
tuberculosis) 		PF05108
(T7SS_ESX1_EccB) 		3 LEU A 258
PRO A 259
LEU A 262
 None
 0.50A 2qd5B-4kk7A:
undetectable		 2qd5B-4kk7A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m03 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		PF05345
(He_PIG) 		3 LEU A 156
PRO A 157
LEU A 160
 None
 0.49A 2qd5B-4m03A:
undetectable		 2qd5B-4m03A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mks ENOLASE 2

(Lactobacillus
gasseri) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		3 LEU A 142
PRO A 143
LEU A 175
 None
 0.34A 2qd5B-4mksA:
undetectable		 2qd5B-4mksA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nt1 ACCELERATED-CELL-DEA
TH 11

(Arabidopsis
thaliana) 		PF08718
(GLTP) 		3 LEU A 158
PRO A 159
LEU A 127
 None
 0.38A 2qd5B-4nt1A:
undetectable		 2qd5B-4nt1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ofy PROTEIN SYG-2

(Caenorhabditis
elegans) 		PF08205
(C2-set_2)
PF13927
(Ig_3) 		3 LEU D  70
PRO D  71
LEU D  62
 None
 0.48A 2qd5B-4ofyD:
undetectable		 2qd5B-4ofyD:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oib INTERCELLULAR
ADHESION MOLECULE 5

(Homo sapiens) 		PF03921
(ICAM_N) 		3 LEU A  97
PRO A  98
LEU A 190
 None
 0.46A 2qd5B-4oibA:
undetectable		 2qd5B-4oibA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmw DIS3-LIKE
EXONUCLEASE 2

(Mus musculus) 		PF00773
(RNB)
PF17216
(Rrp44_CSD1) 		3 LEU A 442
PRO A 443
LEU A 446
 None
 0.42A 2qd5B-4pmwA:
undetectable		 2qd5B-4pmwA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF01648
(ACPS)
PF13416
(SBP_bac_8) 		3 LEU A 382
PRO A 383
LEU A 390
 None
 0.46A 2qd5B-4qvhA:
undetectable		 2qd5B-4qvhA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u89 PHOSPHOPANTETHEINYL
TRANSFERASE PPTT

(Mycobacterium
tuberculosis) 		PF01648
(ACPS) 		3 LEU A  11
PRO A  12
LEU A  19
 None
 0.49A 2qd5B-4u89A:
undetectable		 2qd5B-4u89A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uac CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-)

([Eubacterium]
rectale) 		PF13416
(SBP_bac_8) 		3 LEU A 286
PRO A 287
LEU A 298
 None
 0.41A 2qd5B-4uacA:
undetectable		 2qd5B-4uacA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxx DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 LEU A1439
PRO A1440
LEU A1495
 None
 0.42A 2qd5B-4wxxA:
1.9		 2qd5B-4wxxA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8d SULFOXIDE SYNTHASE
EGTB

(Mycolicibacterium
thermoresistibile) 		PF03781
(FGE-sulfatase)
PF12867
(DinB_2) 		3 LEU A  93
PRO A  94
LEU A  79
 None
 0.41A 2qd5B-4x8dA:
undetectable		 2qd5B-4x8dA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zas CALS13

(Micromonospora
echinospora) 		PF01041
(DegT_DnrJ_EryC1) 		3 LEU A 214
PRO A 215
LEU A 219
 None
 0.48A 2qd5B-4zasA:
undetectable		 2qd5B-4zasA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zg7 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2

(Homo sapiens) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		3 LEU A 429
PRO A 430
LEU A 433
 None
 0.48A 2qd5B-4zg7A:
undetectable		 2qd5B-4zg7A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwv PUTATIVE
AMINOTRANSFERASE

(Actinomadura
melliaura) 		PF01041
(DegT_DnrJ_EryC1) 		3 LEU A 199
PRO A 200
LEU A 204
 None
 0.44A 2qd5B-4zwvA:
undetectable		 2qd5B-4zwvA:
18.99