SIMILAR PATTERNS OF AMINO ACIDS FOR 2QD5_A_CHDA702

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)

(Cupriavidus
necator;
Cupriavidus
necator) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
PF00101
(RuBisCO_small) 		3 LEU I  11
PRO I  12
ARG A 437
 None
 0.51A 2qd5A-1bxnI:
undetectable		 2qd5A-1bxnI:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyy ALDEHYDE
DEHYDROGENASE

(Vibrio harveyi) 		PF00171
(Aldedh) 		3 LEU A  82
PRO A  83
ARG A  93
 None
 0.66A 2qd5A-1eyyA:
2.2		 2qd5A-1eyyA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gjv [3-METHYL-2-OXOBUTAN
OATE DEHYDROGENASE
[LIPOAMIDE]] KINASE

(Rattus
norvegicus) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		3 LEU A 340
PRO A 341
ARG A 252
 AGS  A1383 (-3.9A)
K  A1380 ( 4.6A)
None
 0.49A 2qd5A-1gjvA:
undetectable		 2qd5A-1gjvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR

(Homo sapiens) 		PF01094
(ANF_receptor) 		3 LEU A 107
PRO A 108
ARG A  74
 None
 0.57A 2qd5A-1jdpA:
4.0		 2qd5A-1jdpA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE

(Thermococcus
litoralis) 		PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926) 		3 LEU A 267
PRO A 268
ARG A 124
 None
 0.53A 2qd5A-1k1xA:
0.1		 2qd5A-1k1xA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogy PERIPLASMIC NITRATE
REDUCTASE

(Rhodobacter
sphaeroides) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 LEU A 497
PRO A 498
ARG A 542
 None
 0.63A 2qd5A-1ogyA:
undetectable		 2qd5A-1ogyA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pmi PHOSPHOMANNOSE
ISOMERASE

(Candida
albicans) 		PF01238
(PMI_typeI) 		3 LEU A  95
PRO A  96
ARG A 436
 None
 0.54A 2qd5A-1pmiA:
undetectable		 2qd5A-1pmiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhq PROTEIN (AURACYANIN)

(Chloroflexus
aurantiacus) 		PF00127
(Copper-bind) 		3 LEU A  37
PRO A  38
ARG A  44
 None
None
SO4  A 143 (-3.4A)
 0.57A 2qd5A-1qhqA:
undetectable		 2qd5A-1qhqA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8g HYPOTHETICAL PROTEIN
YBDK

(Escherichia
coli) 		PF04107
(GCS2) 		3 LEU A   3
PRO A   4
ARG A 228
 None
 0.59A 2qd5A-1r8gA:
undetectable		 2qd5A-1r8gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)

(Synechococcus
elongatus;
Synechococcus
elongatus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
no annotation 		3 LEU M  18
PRO M  19
ARG A 435
 None
 0.58A 2qd5A-1rblM:
undetectable		 2qd5A-1rblM:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rwl SERINE/THREONINE-PRO
TEIN KINASE PKND

(Mycobacterium
tuberculosis) 		PF01436
(NHL) 		3 LEU A 228
PRO A 229
ARG A 245
 None
 0.59A 2qd5A-1rwlA:
undetectable		 2qd5A-1rwlA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbx SKI ONCOGENE

(Homo sapiens) 		PF02437
(Ski_Sno) 		3 LEU A 167
PRO A 168
ARG A 152
 None
 0.58A 2qd5A-1sbxA:
undetectable		 2qd5A-1sbxA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sjj ACTININ

(Gallus gallus) 		PF00307
(CH)
PF00435
(Spectrin)
PF08726
(EFhand_Ca_insen) 		3 LEU A 848
PRO A 849
ARG A 859
 None
 0.51A 2qd5A-1sjjA:
undetectable		 2qd5A-1sjjA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su7 CARBON MONOXIDE
DEHYDROGENASE 2

(Carboxydothermus
hydrogenoformans) 		PF03063
(Prismane) 		3 LEU A 550
PRO A 551
ARG A 542
 None
 0.65A 2qd5A-1su7A:
4.1		 2qd5A-1su7A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN

(Halothiobacillus
neapolitanus;
Halothiobacillus
neapolitanus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
PF00101
(RuBisCO_small) 		3 LEU M  19
PRO M  20
ARG A 428
 None
 0.29A 2qd5A-1svdM:
undetectable		 2qd5A-1svdM:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6z HYPOTHETICAL PROTEIN
TTHA0657

(Thermus
thermophilus) 		PF04452
(Methyltrans_RNA) 		3 LEU A  15
PRO A  16
ARG A   5
 None
 0.55A 2qd5A-1v6zA:
undetectable		 2qd5A-1v6zA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wek HYPOTHETICAL PROTEIN
TT1465

(Thermus
thermophilus) 		PF03641
(Lysine_decarbox) 		3 LEU A 138
PRO A 139
ARG A  60
 None
 0.66A 2qd5A-1wekA:
3.2		 2qd5A-1wekA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA

(Escherichia
coli) 		PF00282
(Pyridoxal_deC) 		3 LEU A 223
PRO A 222
ARG A 193
 None
 0.62A 2qd5A-2dgkA:
3.5		 2qd5A-2dgkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fef HYPOTHETICAL PROTEIN
PA2201

(Pseudomonas
aeruginosa) 		PF08929
(DUF1911) 		3 LEU A  16
PRO A  17
ARG A  59
 None
 0.65A 2qd5A-2fefA:
undetectable		 2qd5A-2fefA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hro PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE

(Staphylococcus
carnosus) 		PF00391
(PEP-utilizers)
PF02896
(PEP-utilizers_C)
PF05524
(PEP-utilisers_N) 		3 LEU A 515
PRO A 514
ARG A 552
 None
 0.62A 2qd5A-2hroA:
undetectable		 2qd5A-2hroA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hrz NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Agrobacterium
fabrum) 		PF01370
(Epimerase) 		3 LEU A 143
PRO A 144
ARG A 185
 None
 0.55A 2qd5A-2hrzA:
undetectable		 2qd5A-2hrzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ie8 PHOSPHOGLYCERATE
KINASE

(Thermus
caldophilus) 		PF00162
(PGK) 		3 LEU A 160
PRO A 161
ARG A  13
 None
 0.60A 2qd5A-2ie8A:
undetectable		 2qd5A-2ie8A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inc TOLUENE, O-XYLENE
MONOOXYGENASE
OXYGENASE SUBUNIT

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox)
PF04945
(YHS) 		3 LEU A 393
PRO A 394
ARG A 453
 None
 0.63A 2qd5A-2incA:
undetectable		 2qd5A-2incA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jd4 LAMININ SUBUNIT
ALPHA-1

(Mus musculus) 		PF00054
(Laminin_G_1)
PF02210
(Laminin_G_2) 		3 LEU A2826
PRO A2827
ARG A2833
 None
 0.42A 2qd5A-2jd4A:
undetectable		 2qd5A-2jd4A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kbn CONSERVED PROTEIN

(Methanosarcina
mazei) 		no annotation 3 LEU A  58
PRO A  59
ARG A  70
 None
 0.42A 2qd5A-2kbnA:
undetectable		 2qd5A-2kbnA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG

(Mycobacterium
tuberculosis) 		no annotation 3 LEU A  25
PRO A  26
ARG A  48
 None
 0.65A 2qd5A-2mi6A:
undetectable		 2qd5A-2mi6A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n1k FIBRONECTIN

(Homo sapiens) 		PF00041
(fn3) 		3 LEU A  57
PRO A  58
ARG A  29
 None
 0.64A 2qd5A-2n1kA:
undetectable		 2qd5A-2n1kA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nqn MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
MOEA

(Escherichia
coli) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		3 LEU A 161
PRO A 162
ARG A 155
 None
 0.63A 2qd5A-2nqnA:
5.0		 2qd5A-2nqnA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR

(Arabidopsis
thaliana) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		3 LEU A 262
PRO A 263
ARG A 287
 None
 0.62A 2qd5A-2og2A:
3.1		 2qd5A-2og2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p50 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Escherichia
coli) 		PF01979
(Amidohydro_1) 		3 LEU A  37
PRO A  38
ARG A  44
 None
 0.58A 2qd5A-2p50A:
undetectable		 2qd5A-2p50A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q7s N-FORMYLGLUTAMATE
AMIDOHYDROLASE

(Cupriavidus
pinatubonensis) 		PF05013
(FGase) 		3 LEU A  23
PRO A  24
ARG A 280
 None
 0.51A 2qd5A-2q7sA:
undetectable		 2qd5A-2q7sA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY

(Ruegeria
pomeroyi) 		PF00072
(Response_reg) 		3 LEU A 126
PRO A 127
ARG A  92
 None
 0.55A 2qd5A-2qsjA:
5.5		 2qd5A-2qsjA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ra9 UNCHARACTERIZED
PROTEIN DUF1285

(Shewanella
baltica) 		PF06938
(DUF1285) 		3 LEU A 127
PRO A 128
ARG A  93
 None
 0.59A 2qd5A-2ra9A:
undetectable		 2qd5A-2ra9A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1y PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM

(Bos taurus) 		PF02192
(PI3K_p85B) 		3 LEU A  26
PRO A  27
ARG A  54
 None
 0.30A 2qd5A-2v1yA:
undetectable		 2qd5A-2v1yA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8o FLAVIVIRIN PROTEASE
NS3

(Murray Valley
encephalitis
virus) 		PF00271
(Helicase_C)
PF07652
(Flavi_DEAD) 		3 LEU A 547
PRO A 544
ARG A 441
 None
 0.62A 2qd5A-2v8oA:
3.4		 2qd5A-2v8oA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y6e UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 4

(Homo sapiens) 		PF00443
(UCH) 		3 LEU A 479
PRO A 480
ARG A 779
 None
 0.48A 2qd5A-2y6eA:
undetectable		 2qd5A-2y6eA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzr PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Methanocaldococcus
jannaschii) 		PF01680
(SOR_SNZ)
PF05690
(ThiG) 		3 LEU A 241
PRO A 242
ARG A 137
 CL  A 507 (-3.9A)
None
CL  A 506 (-3.1A)
 0.62A 2qd5A-2yzrA:
undetectable		 2qd5A-2yzrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkj [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 4

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		3 LEU A 334
PRO A 335
ARG A 261
 ADP  A 501 (-4.0A)
None
ADP  A 501 (-3.7A)
 0.59A 2qd5A-2zkjA:
undetectable		 2qd5A-2zkjA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3amj ZINC PEPTIDASE
INACTIVE SUBUNIT

(Sphingomonas
sp. A1) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		3 LEU B 393
PRO B 394
ARG B 374
 None
 0.65A 2qd5A-3amjB:
undetectable		 2qd5A-3amjB:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		3 LEU A 101
PRO A 102
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   2 (-3.6A)
 0.52A 2qd5A-3aqiA:
53.6		 2qd5A-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn3 INTERCELLULAR
ADHESION MOLECULE 5

(Homo sapiens) 		PF03921
(ICAM_N) 		3 LEU B  97
PRO B  98
ARG B 128
 None
 0.66A 2qd5A-3bn3B:
undetectable		 2qd5A-3bn3B:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gov MASP-1

(Homo sapiens) 		PF00089
(Trypsin) 		3 LEU B 573
PRO B 574
ARG B 693
 None
 0.56A 2qd5A-3govB:
undetectable		 2qd5A-3govB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqc DNA REPAIR PROTEIN
REV1

(Homo sapiens) 		PF00817
(IMS)
PF11799
(IMS_C) 		3 LEU A 649
PRO A 650
ARG A 693
 None
 0.66A 2qd5A-3gqcA:
undetectable		 2qd5A-3gqcA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hs0 COBRA VENOM FACTOR

(Naja kaouthia) 		PF01835
(A2M_N)
PF07703
(A2M_N_2) 		3 LEU A 166
PRO A 167
ARG A 195
 None
 0.58A 2qd5A-3hs0A:
undetectable		 2qd5A-3hs0A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvr ARF-GAP WITH SH3
DOMAIN, ANK REPEAT
AND PH
DOMAIN-CONTAINING
PROTEIN 3,
ADP-RIBOSYLATION
FACTOR 6

(Homo sapiens;
synthetic
construct) 		PF00025
(Arf)
PF01412
(ArfGap)
PF12796
(Ank_2) 		3 LEU E 577
PRO E 578
ARG E 550
 None
 0.66A 2qd5A-3lvrE:
4.7		 2qd5A-3lvrE:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m07 PUTATIVE ALPHA
AMYLASE

(Salmonella
enterica) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		3 LEU A 136
PRO A 137
ARG A 130
 None
 0.61A 2qd5A-3m07A:
undetectable		 2qd5A-3m07A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m62 UBIQUITIN
CONJUGATION FACTOR
E4

(Saccharomyces
cerevisiae) 		PF04564
(U-box)
PF10408
(Ufd2P_core) 		3 LEU A 900
PRO A 901
ARG A 926
 None
 0.63A 2qd5A-3m62A:
undetectable		 2qd5A-3m62A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3msv NUCLEAR IMPORT
ADAPTOR, NRO1

(Schizosaccharomyces
pombe) 		PF12753
(Nro1) 		3 LEU A 112
PRO A 113
ARG A 101
 None
 0.64A 2qd5A-3msvA:
undetectable		 2qd5A-3msvA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o07 PYRIDOXINE
BIOSYNTHESIS PROTEIN
SNZ1

(Saccharomyces
cerevisiae) 		PF01680
(SOR_SNZ) 		3 LEU A 205
PRO A 206
ARG A 137
 None
 0.66A 2qd5A-3o07A:
1.8		 2qd5A-3o07A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5a PERIPLASMIC NITRATE
REDUCTASE

(Cupriavidus
necator) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 LEU A 497
PRO A 498
ARG A 542
 None
 0.61A 2qd5A-3o5aA:
undetectable		 2qd5A-3o5aA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU B 788
PRO B 789
ARG B 706
 None
 0.64A 2qd5A-3ohmB:
3.1		 2qd5A-3ohmB:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2m POSSIBLE HYDROLASE

(Mycobacterium
tuberculosis) 		PF12697
(Abhydrolase_6) 		3 LEU A  61
PRO A  62
ARG A 231
 None
 0.61A 2qd5A-3p2mA:
3.5		 2qd5A-3p2mA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvf FOMA PROTEIN

(Streptomyces
wedmorensis) 		PF00696
(AA_kinase) 		3 LEU A 157
PRO A 158
ARG A 151
 None
 0.61A 2qd5A-3qvfA:
3.0		 2qd5A-3qvfA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3riq TAILSPIKE PROTEIN

(Salmonella
virus 9NA) 		PF09251
(PhageP22-tail) 		3 LEU A 436
PRO A 437
ARG A 354
 None
 0.61A 2qd5A-3riqA:
undetectable		 2qd5A-3riqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s06 MOTILITY PROTEIN B

(Helicobacter
pylori) 		PF00691
(OmpA) 		3 LEU A 119
PRO A 120
ARG A 143
 None
 0.63A 2qd5A-3s06A:
undetectable		 2qd5A-3s06A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgw V-TYPE ATP SYNTHASE
BETA CHAIN

(Methanosarcina
mazei) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		3 LEU A 436
PRO A 437
ARG A 443
 None
 0.65A 2qd5A-3tgwA:
2.2		 2qd5A-3tgwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3viu PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE 2

(Thermus
thermophilus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		3 LEU A 682
PRO A 683
ARG A 471
 None
 0.60A 2qd5A-3viuA:
undetectable		 2qd5A-3viuA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmr PROLINE
IMINOPEPTIDASE

(Streptomyces
halstedii) 		PF00561
(Abhydrolase_1) 		3 LEU A 153
PRO A 154
ARG A 180
 None
 0.50A 2qd5A-3wmrA:
3.3		 2qd5A-3wmrA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrc GALLATE DIOXYGENASE

(Sphingomonas
paucimobilis) 		PF02900
(LigB)
PF07746
(LigA) 		3 LEU A 134
PRO A 135
ARG A 143
 None
 0.64A 2qd5A-3wrcA:
undetectable		 2qd5A-3wrcA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfv CRISPR-ASSOCIATED
ENDORIBONUCLEASE
CAS6 1

(Sulfolobus
solfataricus) 		PF10040
(CRISPR_Cas6) 		3 LEU A  19
PRO A  20
ARG A  64
 None
 0.51A 2qd5A-3zfvA:
undetectable		 2qd5A-3zfvA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkx HISTONE DEACETYLASE
1

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		3 LEU B 293
PRO B 294
ARG B 169
 None
 0.51A 2qd5A-4bkxB:
undetectable		 2qd5A-4bkxB:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e7w GLYCOGEN SYNTHASE
KINASE 3

(Ustilago maydis) 		PF00069
(Pkinase) 		3 LEU A 337
PRO A 338
ARG A 325
 None
 0.63A 2qd5A-4e7wA:
undetectable		 2qd5A-4e7wA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1h SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		3 LEU A 142
PRO A 143
ARG A  65
 None
 0.66A 2qd5A-4g1hA:
undetectable		 2qd5A-4g1hA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1j SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		3 LEU A 149
PRO A 150
ARG A  65
 None
 0.51A 2qd5A-4g1jA:
undetectable		 2qd5A-4g1jA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnk 1-PHOSPHATIDYLINOSIT
OL 4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU B 788
PRO B 789
ARG B 706
 None
 0.65A 2qd5A-4gnkB:
3.2		 2qd5A-4gnkB:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0n DNMT2

(Spodoptera
frugiperda) 		PF00145
(DNA_methylase) 		3 LEU A 301
PRO A 302
ARG A 312
 None
 0.66A 2qd5A-4h0nA:
undetectable		 2qd5A-4h0nA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ilr CRISPR-ASSOCIATED
ENDORIBONUCLEASE
CAS6 2

(Sulfolobus
solfataricus) 		PF10040
(CRISPR_Cas6) 		3 LEU A  19
PRO A  20
ARG A  64
 None
 0.55A 2qd5A-4ilrA:
undetectable		 2qd5A-4ilrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4juu EPIMERASE

(Xanthomonas
campestris) 		PF05544
(Pro_racemase) 		3 LEU A  65
PRO A  66
ARG A  37
 PO4  A 402 ( 4.7A)
PO4  A 402 (-4.2A)
None
 0.46A 2qd5A-4juuA:
undetectable		 2qd5A-4juuA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jza UNCHARACTERIZED
PROTEIN

(Legionella
longbeachae) 		no annotation 3 LEU A 626
PRO A 627
ARG A 637
 None
 0.44A 2qd5A-4jzaA:
2.6		 2qd5A-4jzaA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF08718
(GLTP) 		3 LEU A 213
PRO A 214
ARG A  90
 None
 0.61A 2qd5A-4kf6A:
undetectable		 2qd5A-4kf6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lk4 VESB PROTEASE

(Vibrio cholerae) 		PF00089
(Trypsin) 		3 LEU A 310
PRO A 311
ARG A 367
 None
 0.58A 2qd5A-4lk4A:
undetectable		 2qd5A-4lk4A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxf TREHALOSE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 LEU A 406
PRO A 407
ARG A 313
 None
 0.63A 2qd5A-4lxfA:
undetectable		 2qd5A-4lxfA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 3A,
CHLOROPLASTIC

(Pisum sativum;
Pisum sativum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
PF00101
(RuBisCO_small) 		3 LEU S  18
PRO S  19
ARG A 435
 None
 0.55A 2qd5A-4mkvS:
undetectable		 2qd5A-4mkvS:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7r GLUTAMYL-TRNA
REDUCTASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00745
(GlutR_dimer)
PF01488
(Shikimate_DH)
PF05201
(GlutR_N) 		3 LEU A 271
PRO A 272
ARG A 280
 None
 0.45A 2qd5A-4n7rA:
3.3		 2qd5A-4n7rA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ogc HNH ENDONUCLEASE
DOMAIN PROTEIN

(Actinomyces
naeslundii) 		PF01844
(HNH) 		3 LEU A 422
PRO A 423
ARG A 391
 None
 0.60A 2qd5A-4ogcA:
undetectable		 2qd5A-4ogcA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A

(Pseudomonas
mendocina) 		PF02332
(Phenol_Hydrox) 		3 LEU A 393
PRO A 394
ARG A 453
 None
 0.63A 2qd5A-4p1cA:
undetectable		 2qd5A-4p1cA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4per ANGIOGENIN

(Gallus gallus) 		PF00074
(RnaseA) 		3 LEU B  75
PRO B  76
ARG B  54
 None
 0.53A 2qd5A-4perB:
undetectable		 2qd5A-4perB:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rft COAT PROTEIN

(Redspotted
grouper nervous
necrosis virus) 		no annotation 3 LEU A  89
PRO A  90
ARG A 202
 None
 0.41A 2qd5A-4rftA:
undetectable		 2qd5A-4rftA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uhm OMEGA AMINO
ACID-PYRUVATE
AMINOTRANSFERASE

(Pseudomonas sp.) 		PF00202
(Aminotran_3) 		3 LEU A 182
PRO A 183
ARG A 244
 None
None
GOL  A1455 (-3.3A)
 0.58A 2qd5A-4uhmA:
undetectable		 2qd5A-4uhmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wq5 TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB

(Escherichia
coli) 		PF00814
(Peptidase_M22) 		3 LEU C  87
PRO C  88
ARG C   2
 None
 0.59A 2qd5A-4wq5C:
undetectable		 2qd5A-4wq5C:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwe DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1

(Homo sapiens) 		PF01966
(HD) 		3 LEU A 476
PRO A 477
ARG A 470
 None
 0.49A 2qd5A-4zweA:
undetectable		 2qd5A-4zweA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		3 LEU A 368
PRO A 369
ARG A 412
 None
 0.66A 2qd5A-5bnzA:
2.9		 2qd5A-5bnzA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6u AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF12897
(Aminotran_MocR) 		3 LEU A  75
PRO A  76
ARG A  59
 None
 0.59A 2qd5A-5c6uA:
undetectable		 2qd5A-5c6uA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chc DMSO REDUCTASE
FAMILY TYPE II
ENZYME,
MOLYBDOPTERIN
SUBUNIT

(Azospira oryzae) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 LEU A 579
PRO A 580
ARG A 625
 None
 0.42A 2qd5A-5chcA:
undetectable		 2qd5A-5chcA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csc CITRATE SYNTHASE

(Gallus gallus) 		PF00285
(Citrate_synt) 		3 LEU B  92
PRO B  89
ARG B 329
 None
 0.63A 2qd5A-5cscB:
undetectable		 2qd5A-5cscB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3j RESPONSE REGULATOR
RSTA

(Acinetobacter
baumannii) 		PF00072
(Response_reg) 		3 LEU A  61
PRO A  62
ARG A  46
 None
 0.41A 2qd5A-5e3jA:
5.4		 2qd5A-5e3jA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7c ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 LEU A 144
PRO A 145
ARG A 175
 None
 0.54A 2qd5A-5f7cA:
undetectable		 2qd5A-5f7cA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k2z PYRIDOXAL
5'-PHOSPHATE
SYNTHASE SUBUNIT
PDX1.3

(Arabidopsis
thaliana) 		PF01680
(SOR_SNZ) 		3 LEU A 221
PRO A 222
ARG A 154
 None
None
SO4  A 402 (-3.1A)
 0.62A 2qd5A-5k2zA:
undetectable		 2qd5A-5k2zA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbp GLYCOSYL HYDROLASE,
FAMILY 38

(Enterococcus
faecalis) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		3 LEU A 609
PRO A 610
ARG A 670
 None
 0.48A 2qd5A-5kbpA:
undetectable		 2qd5A-5kbpA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnt PYRIDOXAL
5'-PHOSPHATE
SYNTHASE SUBUNIT
PDX1.1

(Arabidopsis
thaliana) 		PF01680
(SOR_SNZ) 		3 LEU A 222
PRO A 223
ARG A 155
 None
None
PO4  A 402 (-2.8A)
 0.64A 2qd5A-5lntA:
undetectable		 2qd5A-5lntA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m1q PHAGE TERMINASE
LARGE SUBUNIT

(Thermus phage
G20c) 		PF17289
(Terminase_6C) 		3 LEU A 269
PRO A 270
ARG A 284
 None
 0.52A 2qd5A-5m1qA:
2.2		 2qd5A-5m1qA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		no annotation 3 LEU A 161
PRO A 162
ARG A  36
 None
 0.48A 2qd5A-5n48A:
undetectable		 2qd5A-5n48A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbs BETA-GLUCOSIDASE

(Neurospora
crassa) 		no annotation 3 LEU A 731
PRO A 732
ARG A 325
 MAN  A1126 (-4.4A)
MAN  A1126 (-3.6A)
None
 0.60A 2qd5A-5nbsA:
3.2		 2qd5A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1

(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
PF00101
(RuBisCO_small) 		3 LEU I  11
PRO I  12
ARG A 436
 None
 0.42A 2qd5A-5nv3I:
undetectable		 2qd5A-5nv3I:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o4g RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-2

(Homo sapiens) 		no annotation 3 LEU C  43
PRO C  44
ARG C  25
 None
 0.58A 2qd5A-5o4gC:
undetectable		 2qd5A-5o4gC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o5o RNASE ADAPTER
PROTEIN RAPZ

(Escherichia
coli) 		PF03668
(ATP_bind_2) 		3 LEU A   3
PRO A  80
ARG A  42
 None
 0.65A 2qd5A-5o5oA:
undetectable		 2qd5A-5o5oA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tic ACYL-COA
THIOESTERASE I

(Escherichia
coli) 		PF13472
(Lipase_GDSL_2) 		3 LEU A 109
PRO A 110
ARG A  77
 None
 0.66A 2qd5A-5ticA:
5.7		 2qd5A-5ticA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7u TREHALOSE SYNTHASE

(Thermobaculum
terrenum) 		no annotation 3 LEU A 416
PRO A 417
ARG A 342
 None
 0.40A 2qd5A-5x7uA:
undetectable		 2qd5A-5x7uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs PUTATIVE CORE
PROTEIN NTPASE/VP5

(Aquareovirus C) 		no annotation 3 LEU 4 239
PRO 4 240
ARG 4  36
 None
 0.60A 2qd5A-5zvs4:
undetectable		 2qd5A-5zvs4:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6h20 -

(-) 		no annotation 3 LEU A  42
PRO A  43
ARG A 242
 None
 0.38A 2qd5A-6h20A:
undetectable		 2qd5A-6h20A:
undetectable