SIMILAR PATTERNS OF AMINO ACIDS FOR 2QD3_A_CHDA502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ep2 DIHYDROOROTATE
DEHYDROGENASE B
(PYRK SUBUNIT)

(Lactococcus
lactis) 		PF00175
(NAD_binding_1)
PF10418
(DHODB_Fe-S_bind) 		4 MET B 220
PRO B 124
SER B  56
GLY B 118
 None
None
FAD  B 503 (-3.2A)
None
 1.02A 2qd3A-1ep2B:
3.5		 2qd3A-1ep2B:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ep2 DIHYDROOROTATE
DEHYDROGENASE B
(PYRK SUBUNIT)

(Lactococcus
lactis) 		PF00175
(NAD_binding_1)
PF10418
(DHODB_Fe-S_bind) 		4 MET B 220
PRO B 124
SER B  56
GLY B 119
 None
None
FAD  B 503 (-3.2A)
None
 1.02A 2qd3A-1ep2B:
3.5		 2qd3A-1ep2B:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Escherichia
coli) 		PF02350
(Epimerase_2) 		4 PRO A 298
SER A 299
VAL A 322
GLY A 320
 None
CL  A1379 ( 4.6A)
None
None
 1.08A 2qd3A-1f6dA:
2.7		 2qd3A-1f6dA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fpr PROTEIN-TYROSINE
PHOSPHATASE 1C

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 SER A 455
VAL A 424
GLY A 423
TRP A 419
 None
 0.63A 2qd3A-1fprA:
undetectable		 2qd3A-1fprA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqm DNA-DIRECTED RNA
POLYMERASE SUBUNIT
ALPHA

(Thermus
aquaticus) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		4 PRO A 172
SER A 203
VAL A 147
GLY A 146
 None
 0.89A 2qd3A-1hqmA:
undetectable		 2qd3A-1hqmA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idj PECTIN LYASE A

(Aspergillus
niger) 		PF00544
(Pec_lyase_C) 		4 SER A 234
VAL A 150
GLY A 175
TRP A 212
 None
 1.12A 2qd3A-1idjA:
undetectable		 2qd3A-1idjA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lar PROTEIN (LAR)

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 SER A1814
VAL A1782
GLY A1781
TRP A1777
 None
 0.81A 2qd3A-1larA:
2.0		 2qd3A-1larA:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae) 		PF00762
(Ferrochelatase) 		4 PRO A 238
VAL A 277
GLY A 278
TRP A 282
 None
 0.24A 2qd3A-1lbqA:
48.3		 2qd3A-1lbqA:
49.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n26 IL-6 RECEPTOR ALPHA
CHAIN

(Homo sapiens) 		PF00047
(ig)
PF09240
(IL6Ra-bind) 		4 PRO A  98
SER A 184
GLY A 116
TRP A 115
 None
 1.00A 2qd3A-1n26A:
undetectable		 2qd3A-1n26A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oxx ABC TRANSPORTER, ATP
BINDING PROTEIN

(Sulfolobus
solfataricus) 		PF00005
(ABC_tran) 		4 PRO K 317
SER K 320
VAL K 340
GLY K 297
 None
 1.13A 2qd3A-1oxxK:
undetectable		 2qd3A-1oxxK:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pp1 P40 NUCLEOPROTEIN

(Borna disease
virus) 		PF06407
(BDV_P40) 		4 SER X 205
VAL X  95
GLY X  94
TRP X 202
 None
 1.02A 2qd3A-1pp1X:
undetectable		 2qd3A-1pp1X:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qzz ACLACINOMYCIN-10-HYD
ROXYLASE

(Streptomyces
purpurascens) 		PF00891
(Methyltransf_2) 		4 ARG A 184
SER A 335
VAL A 251
GLY A 281
 None
 1.08A 2qd3A-1qzzA:
2.9		 2qd3A-1qzzA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rdk MANNOSE-BINDING
PROTEIN-C

(Rattus rattus) 		PF00059
(Lectin_C) 		4 PRO 1 213
SER 1 215
VAL 1 194
GLY 1 195
 CL  1   3 (-4.6A)
None
None
None
 0.80A 2qd3A-1rdk1:
undetectable		 2qd3A-1rdk1:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ry2 ACETYL-COENZYME A
SYNTHETASE 1

(Saccharomyces
cerevisiae) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 PRO A 530
SER A 531
VAL A 108
TRP A 125
 None
 0.90A 2qd3A-1ry2A:
4.4		 2qd3A-1ry2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE

(Populus tremula) 		PF00722
(Glyco_hydro_16)
PF06955
(XET_C) 		4 MET A 262
ARG A 268
VAL A 159
GLY A 158
 None
 0.99A 2qd3A-1un1A:
undetectable		 2qd3A-1un1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xpg 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 PRO A 115
SER A 157
VAL A  72
GLY A  75
 None
 1.04A 2qd3A-1xpgA:
undetectable		 2qd3A-1xpgA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afb 2-KETO-3-DEOXYGLUCON
ATE KINASE

(Thermotoga
maritima) 		PF00294
(PfkB) 		4 MET A  10
ARG A 168
VAL A 276
GLY A 277
 None
 1.03A 2qd3A-2afbA:
undetectable		 2qd3A-2afbA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bht CYSTEINE SYNTHASE B

(Escherichia
coli) 		PF00291
(PALP) 		4 MET A  95
SER A 288
VAL A 254
GLY A 253
 None
 0.86A 2qd3A-2bhtA:
undetectable		 2qd3A-2bhtA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csd TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 MET A 325
PRO A 330
VAL A  85
GLY A  84
 None
 1.09A 2qd3A-2csdA:
undetectable		 2qd3A-2csdA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0o DIOL
DEHYDRATASE-REACTIVA
TING FACTOR LARGE
SUBUNIT
DIOL
DEHYDRATASE-REACTIVA
TING FACTOR SMALL
SUBUNIT

(Klebsiella
oxytoca;
Klebsiella
oxytoca) 		PF08841
(DDR)
PF02288
(Dehydratase_MU) 		4 ARG B  96
SER A 243
VAL A 169
GLY A 168
 None
None
None
MG  A1005 ( 4.4A)
 1.06A 2qd3A-2d0oB:
undetectable		 2qd3A-2d0oB:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6r BIFUNCTIONAL
COENZYME A SYNTHASE

(Mus musculus) 		PF01121
(CoaE) 		4 MET A 224
SER A  74
VAL A 191
GLY A  67
 None
 1.08A 2qd3A-2f6rA:
2.5		 2qd3A-2f6rA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus luteus;
Lupinus luteus) 		PF01112
(Asparaginase_2)
PF01112
(Asparaginase_2) 		4 ARG B 251
PRO B 226
SER A  97
GLY B 246
 None
None
None
CL  B 406 ( 3.8A)
 0.85A 2qd3A-2gezB:
undetectable		 2qd3A-2gezB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv2 FORMATE
DEHYDROGENASE H

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 PRO X 331
VAL X 309
MET X 297
TRP X 295
 None
None
UNX  X 804 (-3.8A)
None
 1.02A 2qd3A-2iv2X:
undetectable		 2qd3A-2iv2X:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kfg EH DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF12763
(EF-hand_4) 		5 PRO A 132
SER A 134
VAL A  46
GLY A  47
TRP A  44
 None
 1.17A 2qd3A-2kfgA:
undetectable		 2qd3A-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nda MID-CELL-ANCHORED
PROTEIN Z

(Streptococcus
pneumoniae) 		no annotation 4 MET A  10
ARG A  21
VAL A  17
GLY A  16
 None
 1.15A 2qd3A-2ndaA:
undetectable		 2qd3A-2ndaA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2no5 (S)-2-HALOACID
DEHALOGENASE IVA

(Burkholderia
cepacia) 		PF13419
(HAD_2) 		4 MET A 125
SER A 133
VAL A  19
GLY A  14
 None
None
None
ASL  A  11 ( 4.2A)
 1.07A 2qd3A-2no5A:
2.3		 2qd3A-2no5A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjt NICOTINAMIDE-NUCLEOT
IDE
ADENYLYLTRANSFERASE

(Francisella
tularensis) 		no annotation 4 ARG B 249
SER B 280
VAL B 206
GLY B 234
 MN  B 505 ( 4.2A)
None
None
MN  B 507 ( 4.4A)
 1.02A 2qd3A-2qjtB:
3.1		 2qd3A-2qjtB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwq GLUCOSE
DEHYDROGENASE

(Haloferax
mediterranei) 		PF08240
(ADH_N)
PF16912
(Glu_dehyd_C) 		4 PRO A 173
VAL A 268
GLY A 267
TRP A 171
 None
 1.12A 2qd3A-2vwqA:
3.2		 2qd3A-2vwqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wab ENDOGLUCANASE E

(Ruminiclostridium
thermocellum) 		PF00657
(Lipase_GDSL) 		4 SER A 227
VAL A 260
GLY A 261
MET A 263
 BGC  A1337 (-4.7A)
None
None
BGC  A1337 (-4.5A)
 1.08A 2qd3A-2wabA:
3.7		 2qd3A-2wabA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zba TRICHOTHECENE
3-O-ACETYLTRANSFERAS
E

(Fusarium
sporotrichioides) 		PF02458
(Transferase) 		4 ARG A 201
SER A 386
GLY A 172
MET A 170
 None
COA  A 462 ( 2.6A)
None
None
 1.13A 2qd3A-2zbaA:
undetectable		 2qd3A-2zbaA:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		7 MET A  99
PRO A 266
SER A 268
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.36A 2qd3A-3aqiA:
59.6		 2qd3A-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b4y PROBABLE
F420-DEPENDENT
GLUCOSE-6-PHOSPHATE
DEHYDROGENASE FGD1

(Mycobacterium
tuberculosis) 		PF00296
(Bac_luciferase) 		4 PRO A  77
SER A 135
VAL A  74
GLY A 104
 None
None
F42  A 338 (-4.3A)
None
 1.13A 2qd3A-3b4yA:
undetectable		 2qd3A-3b4yA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3co8 ALANINE RACEMASE

(Oenococcus oeni) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 ARG A 367
SER A 350
GLY A 288
TRP A 289
 None
 1.04A 2qd3A-3co8A:
undetectable		 2qd3A-3co8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE

(Burkholderia
pseudomallei) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 SER A 334
VAL A  80
GLY A 314
TRP A 259
 None
 1.14A 2qd3A-3d6bA:
undetectable		 2qd3A-3d6bA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4d ESTERASE D

(Agrobacterium
fabrum) 		PF00756
(Esterase) 		4 PRO A 176
SER A 182
GLY A 152
MET A 148
 None
 1.11A 2qd3A-3e4dA:
2.4		 2qd3A-3e4dA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE

(Archaeoglobus
fulgidus) 		PF01874
(CitG) 		4 MET A 164
PRO A  93
VAL A  67
GLY A  64
 None
 1.14A 2qd3A-3h9pA:
undetectable		 2qd3A-3h9pA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4j AMINOTRANSFERASE,
CLASS III

(Deinococcus
radiodurans) 		PF00202
(Aminotran_3) 		4 PRO A 406
SER A 408
VAL A  40
GLY A 262
 None
 1.03A 2qd3A-3i4jA:
2.0		 2qd3A-3i4jA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jv9 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Neisseria
meningitidis) 		PF03466
(LysR_substrate) 		4 MET A 185
PRO A 268
SER A 207
GLY A 265
 None
 1.15A 2qd3A-3jv9A:
undetectable		 2qd3A-3jv9A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nks PROTOPORPHYRINOGEN
OXIDASE

(Homo sapiens) 		PF01593
(Amino_oxidase) 		4 ARG A  38
PRO A 287
SER A 450
GLY A  11
 None
None
None
FAD  A 479 (-3.4A)
 1.07A 2qd3A-3nksA:
undetectable		 2qd3A-3nksA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps5 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 6

(Homo sapiens) 		PF00017
(SH2)
PF00102
(Y_phosphatase) 		4 SER A 453
VAL A 422
GLY A 421
TRP A 417
 SO4  A 599 (-2.6A)
None
None
None
 0.77A 2qd3A-3ps5A:
undetectable		 2qd3A-3ps5A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvl PUTATIVE HYDANTOIN
RACEMASE

(Klebsiella
pneumoniae) 		PF01177
(Asp_Glu_race) 		4 PRO A  83
SER A  79
VAL A  58
GLY A  59
 None
5HY  A   1 (-3.1A)
None
None
 1.04A 2qd3A-3qvlA:
3.4		 2qd3A-3qvlA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujz METALLOPROTEASE STCE

(Escherichia
coli) 		PF10462
(Peptidase_M66) 		4 MET A 306
PRO A 707
VAL A 692
GLY A 693
 None
 0.95A 2qd3A-3ujzA:
undetectable		 2qd3A-3ujzA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vbe BETA-CYANOALNINE
SYNTHASE

(Glycine max) 		PF00291
(PALP) 		4 SER A 318
VAL A 292
GLY A 253
MET A 227
 PLP  A 500 (-2.6A)
None
None
None
 1.04A 2qd3A-3vbeA:
2.7		 2qd3A-3vbeA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrf NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE

(Bifidobacterium
longum) 		PF07944
(Glyco_hydro_127) 		4 PRO A 468
VAL A 602
GLY A 601
TRP A 469
 None
 0.84A 2qd3A-3wrfA:
undetectable		 2qd3A-3wrfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrf NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE

(Bifidobacterium
longum) 		PF07944
(Glyco_hydro_127) 		4 SER A   7
VAL A 602
GLY A 601
TRP A 469
 None
 1.04A 2qd3A-3wrfA:
undetectable		 2qd3A-3wrfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zif PENTON PROTEIN

(Bovine
mastadenovirus
B) 		PF01686
(Adeno_Penton_B) 		4 PRO M 383
SER M 426
VAL M 345
GLY M 344
 None
 0.93A 2qd3A-3zifM:
undetectable		 2qd3A-3zifM:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5o BIFUNCTIONAL PROTEIN
FOLD

(Pseudomonas
aeruginosa) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 ARG A 239
SER A 152
VAL A 263
GLY A 262
 None
 1.07A 2qd3A-4a5oA:
3.5		 2qd3A-4a5oA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ap3 STEROID
MONOOXYGENASE

(Rhodococcus
rhodochrous) 		PF00743
(FMO-like) 		4 ARG A 123
SER A 455
VAL A  27
GLY A  28
 FAD  A1552 (-4.0A)
FAD  A1552 ( 4.5A)
None
FAD  A1552 (-3.1A)
 1.03A 2qd3A-4ap3A:
2.8		 2qd3A-4ap3A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci6 PROTEIN KINASE YOPO

(Yersinia
enterocolitica) 		PF00069
(Pkinase)
PF09632
(Rac1) 		4 PRO B 297
SER B 291
VAL B 311
GLY B 312
 None
 1.02A 2qd3A-4ci6B:
undetectable		 2qd3A-4ci6B:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dqv PROBABLE PEPTIDE
SYNTHETASE NRP
(PEPTIDE SYNTHASE)

(Mycobacterium
tuberculosis) 		PF07993
(NAD_binding_4) 		4 ARG A  75
PRO A 437
VAL A 427
GLY A 428
 None
 0.77A 2qd3A-4dqvA:
undetectable		 2qd3A-4dqvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fo0 ACTIN-RELATED
PROTEIN 8

(Homo sapiens) 		PF00022
(Actin) 		4 MET A 579
PRO A  68
GLY A 589
TRP A 586
 None
 1.09A 2qd3A-4fo0A:
undetectable		 2qd3A-4fo0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ftw PHOSPHOLIPASE/CARBOX
YLESTERASE

(Rhodobacter
sphaeroides) 		PF02230
(Abhydrolase_2) 		4 MET A 134
PRO A 120
SER A 125
TRP A 121
 None
 1.10A 2qd3A-4ftwA:
3.5		 2qd3A-4ftwA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gs1 DYP-TYPE PEROXIDASE

(Thermobifida
cellulosilytica) 		PF04261
(Dyp_perox) 		4 MET A 183
ARG A 353
VAL A  84
GLY A 187
 None
 1.01A 2qd3A-4gs1A:
undetectable		 2qd3A-4gs1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwg UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Rickettsia
bellii) 		PF02350
(Epimerase_2) 		4 MET A 170
SER A 166
GLY A  94
MET A 115
 None
 0.87A 2qd3A-4hwgA:
4.1		 2qd3A-4hwgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iim INTERSECTIN-1

(Homo sapiens) 		PF00018
(SH3_1) 		4 PRO A 962
SER A 964
MET A 948
TRP A 949
 None
 0.94A 2qd3A-4iimA:
undetectable		 2qd3A-4iimA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ikc PHOSPHOTIDYLINOSITOL
PHOSPHATASE PTPRQ

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 SER A2879
VAL A2850
GLY A2849
TRP A2845
 SO4  A3001 ( 2.6A)
None
None
None
 0.70A 2qd3A-4ikcA:
undetectable		 2qd3A-4ikcA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnf GLUTAMINE SYNTHETASE

(Bacillus
subtilis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 MET A 244
PRO A 291
SER A 295
GLY A  30
 None
 1.08A 2qd3A-4lnfA:
undetectable		 2qd3A-4lnfA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxy WLARD, A SUGAR
3N-FORMYL
TRANSFERASE

(Campylobacter
jejuni) 		PF00551
(Formyl_trans_N) 		4 ARG A 192
PRO A 112
SER A 120
GLY A 105
 1YA  A 301 (-4.3A)
None
None
None
 1.13A 2qd3A-4lxyA:
2.8		 2qd3A-4lxyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nho PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX23

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 MET A 588
ARG A 623
PRO A 387
GLY A 384
 None
None
None
SO4  A 904 (-3.5A)
 1.05A 2qd3A-4nhoA:
2.9		 2qd3A-4nhoA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8v ALGINATE
BIOSYNTHESIS PROTEIN
ALGJ

(Pseudomonas
putida) 		PF16822
(ALGX) 		4 ARG A 182
PRO A 132
VAL A 185
GLY A 197
 None
 0.98A 2qd3A-4o8vA:
undetectable		 2qd3A-4o8vA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oir DNA-DIRECTED RNA
POLYMERASE SUBUNIT
ALPHA

(Thermus
thermophilus) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		4 PRO A 173
SER A 204
VAL A 148
GLY A 147
 None
 0.99A 2qd3A-4oirA:
undetectable		 2qd3A-4oirA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvg TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 ARG A 512
VAL A 428
GLY A 427
TRP A 423
 None
 1.02A 2qd3A-4pvgA:
2.2		 2qd3A-4pvgA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiv BACTERIAL
MICROCOMPARTMENTS
FAMILY PROTEIN

(Aeromonas
hydrophila) 		PF00936
(BMC) 		4 PRO A  79
SER A  84
VAL A  75
GLY A   6
 None
 1.08A 2qd3A-4qivA:
undetectable		 2qd3A-4qivA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A''

(Thermococcus
kodakarensis;
Thermococcus
kodakarensis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF04998
(RNA_pol_Rpb1_5) 		4 ARG C 282
PRO A 879
SER A 882
GLY A 873
 None
 1.06A 2qd3A-4qiwC:
undetectable		 2qd3A-4qiwC:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjy GH127
BETA-L-ARABINOFURANO
SIDASE

(Geobacillus
stearothermophilus) 		PF07944
(Glyco_hydro_127) 		4 PRO A 458
VAL A 587
GLY A 586
TRP A 459
 None
 0.85A 2qd3A-4qjyA:
undetectable		 2qd3A-4qjyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 PRO A  78
SER A 160
VAL A  30
GLY A  29
 None
PG4  A 603 ( 4.9A)
None
None
 0.82A 2qd3A-4rjkA:
undetectable		 2qd3A-4rjkA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvw ZNUD

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 SER A 217
VAL A 148
GLY A 147
MET A 143
 None
 1.15A 2qd3A-4rvwA:
undetectable		 2qd3A-4rvwA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcj POLYSACCHARIDE
DEACETYLASE

(Ammonifex
degensii) 		PF01522
(Polysacc_deac_1) 		4 MET A 162
VAL A 144
GLY A 145
TRP A 156
 None
 0.95A 2qd3A-4wcjA:
undetectable		 2qd3A-4wcjA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y90 TRIOSEPHOSPHATE
ISOMERASE

(Deinococcus
radiodurans) 		PF00121
(TIM) 		4 ARG A 203
PRO A  34
VAL A  38
GLY A  37
 None
 1.14A 2qd3A-4y90A:
undetectable		 2qd3A-4y90A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 PRO A 303
SER A 305
VAL A 258
GLY A 259
 None
None
FAD  A3004 (-3.9A)
FAD  A3004 (-3.2A)
 0.96A 2qd3A-4yswA:
undetectable		 2qd3A-4yswA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3y BENZOYL-COA
REDUCTASE, PUTATIVE
IRON-SULFUR
CLUSTER-BINDING
OXIDOREDUCTASE,
PUTATIVE BENZOYL-COA
REDUCTASE ELECTRON
TRANSFER PROTEIN

(Geobacter
metallireducens;
Geobacter
metallireducens) 		PF01314
(AFOR_C)
PF02730
(AFOR_N)
no annotation 		4 ARG E  53
SER A 185
GLY A  97
MET A  95
 None
MTE  A 703 (-3.0A)
None
None
 1.04A 2qd3A-4z3yE:
undetectable		 2qd3A-4z3yE:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE

(Caulobacter
vibrioides) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 ARG A 213
SER A  84
GLY A 181
MET A 184
 None
 1.07A 2qd3A-5a05A:
4.3		 2qd3A-5a05A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aid MEP2

(Candida
albicans) 		PF00909
(Ammonium_transp) 		4 SER A 199
VAL A 344
GLY A 343
TRP A 339
 None
 0.91A 2qd3A-5aidA:
undetectable		 2qd3A-5aidA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aim TRANSCRIPTION FACTOR
TAU 138 KDA SUBUNIT

(Saccharomyces
cerevisiae) 		no annotation 4 ARG A 633
SER A 579
GLY A 567
MET A 563
 None
 1.11A 2qd3A-5aimA:
undetectable		 2qd3A-5aimA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dlc PYRIDOXINE
5'-PHOSPHATE
SYNTHASE

(Pseudomonas
aeruginosa) 		PF03740
(PdxJ) 		4 MET A  90
PRO A  99
SER A 139
VAL A  55
 None
 1.15A 2qd3A-5dlcA:
undetectable		 2qd3A-5dlcA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4z EPOXIDE HYDROLASE

(Streptomyces
carzinostaticus) 		PF06441
(EHN) 		4 ARG A 342
SER A 185
VAL A 330
GLY A 329
 None
 1.09A 2qd3A-5f4zA:
3.2		 2qd3A-5f4zA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078

(Thermobifida
fusca) 		PF04261
(Dyp_perox) 		4 MET A 146
ARG A 316
VAL A  43
GLY A 150
 None
 0.98A 2qd3A-5fw4A:
undetectable		 2qd3A-5fw4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz1 MESO-DIAMINOPIMELATE
D-DEHYDROGENASE

(Ureibacillus
thermosphaericus) 		PF01113
(DapB_N)
PF16654
(DAPDH_C) 		4 ARG A  37
PRO A 277
SER A 275
GLY A  15
 None
 1.06A 2qd3A-5gz1A:
3.1		 2qd3A-5gz1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 ARG A 344
SER A 454
GLY B1131
MET B1133
 None
 1.07A 2qd3A-5ip9A:
undetectable		 2qd3A-5ip9A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwz CELLULOSE-BINDING
FAMILY II

(Streptomyces
sp. SirexAA-E) 		PF02012
(BNR) 		4 PRO A 150
SER A 151
VAL A  73
GLY A 124
 None
 1.14A 2qd3A-5jwzA:
undetectable		 2qd3A-5jwzA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jyj SPERM-EGG FUSION
PROTEIN JUNO

(Mus musculus) 		PF03024
(Folate_rec) 		4 MET A  28
VAL A 123
GLY A 122
TRP A 106
 None
 0.99A 2qd3A-5jyjA:
undetectable		 2qd3A-5jyjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksw DIHYDROOROTATE
DEHYDROGENASE B
(NAD(+)), ELECTRON
TRANSFER SUBUNIT

(Lactococcus
lactis) 		PF00175
(NAD_binding_1)
PF10418
(DHODB_Fe-S_bind) 		4 MET B 220
PRO B 124
SER B  56
GLY B 118
 None
None
FAD  B 301 (-2.9A)
None
 1.00A 2qd3A-5kswB:
2.7		 2qd3A-5kswB:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lum HEAT SHOCK PROTEIN
BETA-6

(Homo sapiens) 		PF00011
(HSP20) 		4 ARG A 122
PRO A 148
VAL A 127
GLY A 126
 None
 0.97A 2qd3A-5lumA:
undetectable		 2qd3A-5lumA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o5j 30S RIBOSOMAL
PROTEIN S5
30S RIBOSOMAL
PROTEIN S8

(Mycolicibacterium
smegmatis;
Mycolicibacterium
smegmatis) 		PF00333
(Ribosomal_S5)
PF03719
(Ribosomal_S5_C)
PF00410
(Ribosomal_S8) 		4 ARG E 182
PRO H  95
VAL H  97
GLY H 100
 None
 0.96A 2qd3A-5o5jE:
undetectable		 2qd3A-5o5jE:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oh5 RIDL

(Legionella
pneumophila) 		no annotation 4 PRO A  48
SER A  49
VAL A 181
GLY A 180
 None
 1.00A 2qd3A-5oh5A:
undetectable		 2qd3A-5oh5A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila) 		no annotation 4 PRO A  48
SER A  49
VAL A 181
GLY A 180
 None
 0.91A 2qd3A-5ot4A:
undetectable		 2qd3A-5ot4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swn FLUOROACETATE
DEHALOGENASE

(Rhodopseudomonas
palustris) 		PF00561
(Abhydrolase_1) 		5 MET A  96
PRO A  66
SER A  71
VAL A 115
GLY A 112
 None
 1.39A 2qd3A-5swnA:
3.0		 2qd3A-5swnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb MINICHROMOSOME
MAINTENANCE PROTEIN
5

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 PRO 5  83
SER 5  84
VAL 5 160
GLY 5 296
 None
 1.12A 2qd3A-5udb5:
undetectable		 2qd3A-5udb5:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vi6 HISTONE DEACETYLASE
8

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		4 PRO A 350
VAL A 282
GLY A 283
MET A 279
 None
EDO  A 408 (-4.3A)
None
None
 1.15A 2qd3A-5vi6A:
undetectable		 2qd3A-5vi6A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wyh INTERAPTIN

(Legionella
pneumophila) 		no annotation 4 PRO B  48
SER B  49
VAL B 181
GLY B 180
 None
 1.09A 2qd3A-5wyhB:
undetectable		 2qd3A-5wyhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x2q TASTE RECEPTOR, TYPE
1, MEMBER 2A

(Oryzias latipes) 		PF01094
(ANF_receptor) 		4 ARG A 202
SER A 452
VAL A 193
GLY A 194
 None
 0.99A 2qd3A-5x2qA:
4.3		 2qd3A-5x2qA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B
ALTERNATIVE COMPLEX
III SUBUNIT C

(Flavobacterium
johnsoniae;
Flavobacterium
johnsoniae) 		no annotation
no annotation 		4 PRO B 860
SER C 159
VAL B 880
GLY B 881
 None
None
None
F3S  B1101 ( 4.2A)
 1.03A 2qd3A-6btmB:
undetectable		 2qd3A-6btmB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6coy CHLORIDE CHANNEL
PROTEIN 1

(Homo sapiens) 		no annotation 4 PRO A 420
VAL A 229
GLY A 230
MET A 485
 None
None
CL  A1001 (-3.2A)
None
 0.96A 2qd3A-6coyA:
undetectable		 2qd3A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6czx PHOSPHOSERINE
AMINOTRANSFERASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 PRO A 369
VAL A 399
GLY A 400
MET A 402
 None
 1.09A 2qd3A-6czxA:
undetectable		 2qd3A-6czxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d1q RNA
PYROPHOSPHOHYDROLASE

(Escherichia
coli) 		no annotation 4 MET B   1
ARG B  52
VAL B  11
GLY B  38
 None
 1.04A 2qd3A-6d1qB:
undetectable		 2qd3A-6d1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elq CARBON MONOXIDE
DEHYDROGENASE

(Carboxydothermus
hydrogenoformans) 		no annotation 4 MET X 302
PRO X 263
SER X 266
VAL X 526
 None
 1.13A 2qd3A-6elqX:
3.6		 2qd3A-6elqX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6et9 ACETYL-COA
ACETYLTRANSFERASE
THIOLASE

(Methanothermococcus
thermolithotrophicus) 		no annotation 4 ARG A 251
SER A 207
VAL A 376
GLY A 377
 None
 1.13A 2qd3A-6et9A:
undetectable		 2qd3A-6et9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1t CYTOPLASMIC DYNEIN 1
HEAVY CHAIN
1,CYTOPLASMIC DYNEIN
1 HEAVY CHAIN
1,CYTOPLASMIC DYNEIN
1 HEAVY CHAIN
1,DYNEIN HEAVY
CHAIN,CYTOPLASMIC
DYNEIN 1 HEAVY CHAIN
1,CYTOPLASMIC DYNEIN
1 HEAVY CHAIN
1,CYTOPLASMIC DYNEIN
1 HEAVY CHAIN
1,CYTOPLASMIC DYNEIN
1 HEAVY CHAIN
1,DYNEIN HEAVY
CHAIN,CYTOPLASMIC
DYNEIN 1 HEAVY CHAIN
1,CYTOPLASMIC DYNEIN
1 HEAVY CHAIN 1

(Homo sapiens) 		no annotation 4 ARG e 309
VAL e 249
GLY e 248
TRP e 252
 None
 1.14A 2qd3A-6f1te:
undetectable		 2qd3A-6f1te:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN

(Archaeoglobus
fulgidus) 		no annotation 4 PRO A 121
SER A 110
GLY A 213
MET A 211
 None
 0.99A 2qd3A-6fswA:
undetectable		 2qd3A-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gun -

(-) 		no annotation 4 ARG A 148
PRO A  43
GLY A  81
TRP A  38
 None
 0.84A 2qd3A-6gunA:
2.9		 2qd3A-6gunA:
undetectable