SIMILAR PATTERNS OF AMINO ACIDS FOR 2QD2_A_CHDA2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bih HEMOLIN

(Hyalophora
cecropia) 		PF07679
(I-set)
PF13927
(Ig_3) 		4 LEU A 350
ARG A 354
SER A  89
VAL A 392
 None
 1.05A 2qd2A-1bihA:
undetectable		 2qd2A-1bihA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu2 CYCLIN HOMOLOG

(Saimiriine
gammaherpesvirus
2) 		PF00134
(Cyclin_N)
PF09241
(Herp-Cyclin) 		4 LEU A 221
ARG A 215
SER A 194
VAL A 238
 None
 1.17A 2qd2A-1bu2A:
undetectable		 2qd2A-1bu2A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e51 DELTA-AMINOLEVULINIC
ACID DEHYDRATASE

(Homo sapiens) 		PF00490
(ALAD) 		4 LEU A 249
ARG A 243
PRO A 167
MET A 170
 None
 1.20A 2qd2A-1e51A:
0.8		 2qd2A-1e51A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flz URACIL-DNA
GLYCOSYLASE

(Escherichia
coli) 		PF03167
(UDG) 		4 LEU A 121
ARG A 116
PRO A 106
VAL A 223
 None
 1.16A 2qd2A-1flzA:
1.4		 2qd2A-1flzA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ghs 1,3-BETA-GLUCANASE

(Hordeum vulgare) 		PF00332
(Glyco_hydro_17) 		4 MET A  30
LEU A  50
ARG A  15
VAL A   7
 None
 1.16A 2qd2A-1ghsA:
undetectable		 2qd2A-1ghsA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jr7 HYPOTHETICAL 37.4
KDA PROTEIN IN
ILEY-GABD INTERGENIC
REGION

(Escherichia
coli) 		PF08943
(CsiD) 		4 MET A 308
LEU A 174
SER A 131
VAL A  54
 None
 1.01A 2qd2A-1jr7A:
undetectable		 2qd2A-1jr7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nig HYPOTHETICAL PROTEIN
TA1238

(Thermoplasma
acidophilum) 		PF09155
(DUF1940) 		4 MET A 131
LEU A 135
SER A  66
VAL A   9
 None
 1.09A 2qd2A-1nigA:
undetectable		 2qd2A-1nigA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogy PERIPLASMIC NITRATE
REDUCTASE

(Rhodobacter
sphaeroides) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 MET A 189
LEU A 381
SER A 216
VAL A 212
 None
None
MGD  A1804 (-2.3A)
None
 1.00A 2qd2A-1ogyA:
0.3		 2qd2A-1ogyA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ow0 IG ALPHA-1 CHAIN C
REGION
IMMUNOGLOBULIN ALPHA
FC RECEPTOR

(Homo sapiens;
Homo sapiens) 		PF00047
(ig)
PF07654
(C1-set)
no annotation 		4 MET A 433
LEU A 384
ARG C  52
SER A 415
 None
 1.19A 2qd2A-1ow0A:
undetectable		 2qd2A-1ow0A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oyw ATP-DEPENDENT DNA
HELICASE

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF09382
(RQC)
PF16124
(RecQ_Zn_bind) 		4 MET A 127
LEU A 132
ARG A 169
VAL A 145
 None
 0.83A 2qd2A-1oywA:
2.3		 2qd2A-1oywA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjw ENVELOPE PROTEIN

(Japanese
encephalitis
virus) 		PF02832
(Flavi_glycop_C) 		4 LEU A  35
PRO A  85
SER A  90
VAL A  64
 None
 1.10A 2qd2A-1pjwA:
undetectable		 2qd2A-1pjwA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkq HYPOTHETICAL PROTEIN
YIDA

(Escherichia
coli) 		PF08282
(Hydrolase_3) 		4 MET A 156
LEU A 111
ARG A  46
SER A 124
 None
 1.13A 2qd2A-1rkqA:
2.8		 2qd2A-1rkqA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz9 REP PROTEIN

(Adeno-associated
dependoparvovirus
B) 		PF08724
(Rep_N) 		4 LEU A  53
ARG A  61
PRO A  38
SER A  41
 None
 1.16A 2qd2A-1rz9A:
undetectable		 2qd2A-1rz9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 40 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF13177
(DNA_pol3_delta2) 		4 LEU E 167
PRO E  98
SER E 145
VAL E 108
 None
 1.20A 2qd2A-1sxjE:
undetectable		 2qd2A-1sxjE:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT

(Thermus
thermophilus) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 MET B 214
ARG B 237
SER B 179
MET B   6
 None
 1.10A 2qd2A-1umbB:
5.6		 2qd2A-1umbB:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w25 STALKED-CELL
DIFFERENTIATION
CONTROLLING PROTEIN

(Caulobacter
vibrioides) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		4 MET A 376
LEU A 324
ARG A 386
PRO A 320
 C2E  A 503 ( 4.8A)
None
None
None
 1.15A 2qd2A-1w25A:
4.2		 2qd2A-1w25A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z8w PYRROLIDONE-CARBOXYL
ATE PEPTIDASE

(Pyrococcus
furiosus) 		PF01470
(Peptidase_C15) 		4 LEU A 115
PRO A  61
VAL A  36
MET A   1
 None
 1.13A 2qd2A-1z8wA:
4.7		 2qd2A-1z8wA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zkc PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
LIKE 2

(Homo sapiens) 		PF00160
(Pro_isomerase) 		4 MET A 410
LEU A 407
PRO A 422
SER A 415
 None
 1.07A 2qd2A-1zkcA:
undetectable		 2qd2A-1zkcA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE

(Pseudomonas sp.
SY-77-1) 		PF01804
(Penicil_amidase) 		4 ARG C 146
PRO C 127
SER C 122
VAL C 141
 None
 1.12A 2qd2A-2advC:
undetectable		 2qd2A-2advC:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2x ANTIBODY AQC2 FAB
ANTIBODY AQC2 FAB

(Mus musculus;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		4 MET L 179
LEU L 140
SER H 183
VAL L 163
 None
 1.02A 2qd2A-2b2xL:
undetectable		 2qd2A-2b2xL:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmm THERMOSTABLE
HEMOGLOBIN FROM
THERMOBIFIDA FUSCA

(Thermobifida
fusca) 		PF01152
(Bac_globin) 		4 MET A  66
LEU A  63
VAL A 154
MET A 151
 None
None
None
HEM  A1157 (-4.6A)
 1.18A 2qd2A-2bmmA:
1.4		 2qd2A-2bmmA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cqz 177AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF13023
(HD_3) 		4 LEU A 158
ARG A  54
VAL A  57
MET A  63
 None
 1.04A 2qd2A-2cqzA:
undetectable		 2qd2A-2cqzA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iep MUSCLE-SPECIFIC
KINASE RECEPTOR

(Rattus
norvegicus) 		PF07679
(I-set) 		4 LEU A 161
PRO A 127
SER A 201
VAL A 130
 None
 1.02A 2qd2A-2iepA:
undetectable		 2qd2A-2iepA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kjd SODIUM/HYDROGEN
EXCHANGE REGULATORY
COFACTOR NHE-RF1

(Homo sapiens) 		PF00595
(PDZ)
PF09007
(EBP50_C) 		4 LEU A  26
ARG A  56
SER A  49
VAL A  89
 None
 1.21A 2qd2A-2kjdA:
undetectable		 2qd2A-2kjdA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l6k TENSIN-LIKE C1
DOMAIN-CONTAINING
PHOSPHATASE

(Homo sapiens) 		PF00017
(SH2) 		4 LEU A 106
PRO A  87
SER A  85
VAL A  78
 None
 1.09A 2qd2A-2l6kA:
undetectable		 2qd2A-2l6kA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oyr UPF0341 PROTEIN YHIQ

(Shigella
flexneri) 		PF04445
(SAM_MT) 		4 MET A 115
LEU A 126
ARG A 101
SER A 154
 None
None
SAH  A 301 (-4.4A)
SAH  A 301 (-3.4A)
 1.12A 2qd2A-2oyrA:
2.5		 2qd2A-2oyrA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozf EZRIN-RADIXIN-MOESIN
-BINDING
PHOSPHOPROTEIN 50

(Homo sapiens) 		PF00595
(PDZ) 		4 LEU A 168
ARG A 198
SER A 191
VAL A 231
 None
 1.02A 2qd2A-2ozfA:
undetectable		 2qd2A-2ozfA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q47 PROBABLE
TYROSINE-PROTEIN
PHOSPHATASE
AT1G05000

(Arabidopsis
thaliana) 		PF03162
(Y_phosphatase2) 		4 LEU A 139
ARG A 165
SER A  87
VAL A  62
 None
 1.19A 2qd2A-2q47A:
3.0		 2qd2A-2q47A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qar E80-TELSAM DOMAIN
TELSAM DOMAIN

(Escherichia
coli;
Escherichia
coli) 		PF02198
(SAM_PNT)
PF02198
(SAM_PNT) 		4 LEU A  85
ARG A  73
SER A  98
VAL B  80
 NH4  A 201 (-4.9A)
None
None
None
 1.15A 2qd2A-2qarA:
undetectable		 2qd2A-2qarA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rc5 FERREDOXIN-NADP
REDUCTASE

(Leptospira
interrogans) 		PF00175
(NAD_binding_1) 		4 MET A 169
LEU A 171
ARG A 251
SER A 184
 None
 1.16A 2qd2A-2rc5A:
2.7		 2qd2A-2rc5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9q ROUNDABOUT HOMOLOG 1

(Homo sapiens) 		PF07679
(I-set)
PF13927
(Ig_3) 		4 LEU A 211
PRO A 176
SER A 251
VAL A 179
 None
 0.92A 2qd2A-2v9qA:
undetectable		 2qd2A-2v9qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoc PULLULANASE

(Klebsiella
oxytoca) 		PF02922
(CBM_48)
PF03714
(PUD)
PF11852
(DUF3372) 		4 LEU A 272
ARG A 325
PRO A 354
VAL A 351
 None
SO4  A2078 ( 4.1A)
None
None
 1.21A 2qd2A-2yocA:
undetectable		 2qd2A-2yocA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zl5 58 KD CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 LEU A 272
ARG A 269
PRO A 412
VAL A 409
 None
 1.20A 2qd2A-2zl5A:
undetectable		 2qd2A-2zl5A:
24.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		6 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
None
 0.86A 2qd2A-3aqiA:
54.3		 2qd2A-3aqiA:
99.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asp CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 LEU A 490
ARG A 270
PRO A 423
VAL A 420
 None
 1.17A 2qd2A-3aspA:
undetectable		 2qd2A-3aspA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgf F26G19 FAB
F26G19 FAB

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 MET L 175
LEU L 136
SER H 180
VAL L 159
 None
 0.93A 2qd2A-3bgfL:
undetectable		 2qd2A-3bgfL:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvh 25-D1.16 HEAVY CHAIN
25-D1.16 LIGHT CHAIN

(Mus musculus;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		4 MET L 174
LEU L 135
SER H 185
VAL L 158
 None
 0.97A 2qd2A-3cvhL:
undetectable		 2qd2A-3cvhL:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD

(Bacillus
subtilis) 		PF00704
(Glyco_hydro_18) 		4 ARG A 341
PRO A 358
SER A 379
VAL A 372
 None
 1.20A 2qd2A-3cz8A:
undetectable		 2qd2A-3cz8A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3x BIPA

(Vibrio
parahaemolyticus) 		PF00679
(EFG_C) 		4 LEU A  90
ARG A  70
PRO A 123
SER A 169
 None
None
None
EDO  A1001 ( 4.5A)
 1.02A 2qd2A-3e3xA:
undetectable		 2qd2A-3e3xA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f1v DNA POLYMERASE III
SUBUNIT BETA

(Escherichia
coli) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 LEU A 331
ARG A 337
SER A 145
VAL A 347
 None
 0.99A 2qd2A-3f1vA:
undetectable		 2qd2A-3f1vA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC

(Cytophaga
hutchinsonii) 		PF00266
(Aminotran_5) 		5 MET A 146
LEU A 135
ARG A 155
PRO A 174
SER A 170
 None
 1.31A 2qd2A-3ffrA:
undetectable		 2qd2A-3ffrA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fho ATP-DEPENDENT RNA
HELICASE DBP5

(Schizosaccharomyces
pombe) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 LEU A 145
ARG A 177
SER A 160
VAL A 259
 None
 1.16A 2qd2A-3fhoA:
2.6		 2qd2A-3fhoA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igr RIBOSOMAL-PROTEIN-S5
-ALANINE
N-ACETYLTRANSFERASE

(Aliivibrio
fischeri) 		PF13302
(Acetyltransf_3) 		4 LEU A  34
ARG A  29
SER A 144
MET A 113
 None
 1.18A 2qd2A-3igrA:
undetectable		 2qd2A-3igrA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42
PRE-MRNA-SPLICING
FACTOR CWF15

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV)
PF01423
(LSM) 		4 LEU A1019
PRO A1187
SER A1189
VAL h 230
 None
 1.01A 2qd2A-3jb9A:
undetectable		 2qd2A-3jb9A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8z NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 MET A  46
LEU A  41
ARG A 420
SER A  97
 None
 1.19A 2qd2A-3k8zA:
1.9		 2qd2A-3k8zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llq AQUAPORIN Z 2

(Agrobacterium
fabrum) 		PF00230
(MIP) 		4 LEU A 144
PRO A 185
SER A 182
VAL A  85
 None
 1.15A 2qd2A-3llqA:
undetectable		 2qd2A-3llqA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1c ENVELOPE
GLYCOPROTEIN H

(Human
alphaherpesvirus
2) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 ARG A 424
ARG A 527
PRO A 666
SER A 672
 None
 1.15A 2qd2A-3m1cA:
undetectable		 2qd2A-3m1cA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ovg AMIDOHYDROLASE

(Mycoplasma
synoviae) 		PF02126
(PTE) 		4 LEU A 200
ARG A 174
SER A  96
VAL A 121
 None
None
KCX  A 153 ( 3.4A)
None
 1.21A 2qd2A-3ovgA:
undetectable		 2qd2A-3ovgA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tij NUPC FAMILY PROTEIN

(Vibrio cholerae) 		PF01773
(Nucleos_tra2_N)
PF07662
(Nucleos_tra2_C)
PF07670
(Gate) 		4 ARG A 392
PRO A 227
SER A 139
MET A 168
 None
 1.14A 2qd2A-3tijA:
undetectable		 2qd2A-3tijA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucs CHAPERONE-MODULATOR
PROTEIN CBPM

(Klebsiella
pneumoniae) 		PF13591
(MerR_2) 		4 MET A  32
LEU A  30
ARG A  60
VAL A  19
 None
 1.11A 2qd2A-3ucsA:
undetectable		 2qd2A-3ucsA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0w WN1 222-5 FAB
(IGG2A) HEAVY CHAIN
WN1 222-5 FAB
(IGG2A) LIGHT CHAIN

(Mus musculus;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		4 MET L 175
LEU L 136
SER H 178
VAL L 159
 None
 0.98A 2qd2A-3v0wL:
undetectable		 2qd2A-3v0wL:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbm COPPER-CONTAINING
NITRITE REDUCTASE

(Ralstonia
pickettii) 		PF07732
(Cu-oxidase_3)
PF13442
(Cytochrome_CBB3) 		4 LEU A 359
ARG A 327
SER A 342
VAL A  56
 None
 1.03A 2qd2A-3zbmA:
undetectable		 2qd2A-3zbmA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zif HEXON PROTEIN
PENTON PROTEIN

(Bovine
mastadenovirus
B;
Bovine
mastadenovirus
B) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C)
PF01686
(Adeno_Penton_B) 		4 LEU A 312
ARG M 443
ARG M 445
VAL A 897
 None
 1.06A 2qd2A-3zifA:
undetectable		 2qd2A-3zifA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3y 3-KETOSTEROID
DEHYDROGENASE

(Rhodococcus
erythropolis) 		PF00890
(FAD_binding_2) 		4 LEU A  77
ARG A  88
SER A 131
VAL A 499
 None
 1.03A 2qd2A-4c3yA:
undetectable		 2qd2A-4c3yA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4con ANAEROBIC
RIBONUCLEOSIDE-TRIPH
OSPHATE REDUCTASE

(Thermotoga
maritima) 		PF13597
(NRDD) 		4 LEU A 212
PRO A 226
SER A 225
VAL A 174
 None
 1.06A 2qd2A-4conA:
undetectable		 2qd2A-4conA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6z APICOPLAST TIC22,
PUTATIVE

(Plasmodium
falciparum) 		PF04278
(Tic22) 		4 MET A 135
LEU A 168
SER A 263
VAL A 194
 None
 1.17A 2qd2A-4e6zA:
undetectable		 2qd2A-4e6zA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fva 5'-TYROSYL-DNA
PHOSPHODIESTERASE

(Caenorhabditis
elegans) 		PF03372
(Exo_endo_phos) 		4 LEU A 154
PRO A 350
SER A 351
MET A 139
 None
 1.20A 2qd2A-4fvaA:
undetectable		 2qd2A-4fvaA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gew 5'-TYROSYL-DNA
PHOSPHODIESTERASE

(Caenorhabditis
elegans) 		PF03372
(Exo_endo_phos)
PF14555
(UBA_4) 		4 LEU A 154
PRO A 350
SER A 351
MET A 139
 None
 1.18A 2qd2A-4gewA:
undetectable		 2qd2A-4gewA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN

(Homo sapiens;
Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		4 MET L 175
LEU L 136
SER H 179
VAL L 159
 None
 1.11A 2qd2A-4idjL:
undetectable		 2qd2A-4idjL:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9q BENZOYLFORMATE
DECARBOXYLASE

(Polynucleobacter
necessarius) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A  12
PRO A  91
SER A  58
VAL A 154
 None
 1.12A 2qd2A-4k9qA:
3.1		 2qd2A-4k9qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9q BENZOYLFORMATE
DECARBOXYLASE

(Polynucleobacter
necessarius) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A  15
PRO A  91
SER A  58
VAL A 154
 None
 1.20A 2qd2A-4k9qA:
3.1		 2qd2A-4k9qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lds BICYCLOMYCIN
RESISTANCE PROTEIN
TCAB

(Staphylococcus
epidermidis) 		PF00083
(Sugar_tr) 		4 LEU A 422
ARG A 303
SER A 376
VAL A 358
 None
 1.07A 2qd2A-4ldsA:
undetectable		 2qd2A-4ldsA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ncc FAB FRAGMENT HEAVY
FAB FRAGMENT LIGHT

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 MET L 174
LEU L 135
SER H 184
VAL L 158
 None
 1.01A 2qd2A-4nccL:
undetectable		 2qd2A-4nccL:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 LEU A 899
ARG A 927
PRO A 886
SER A 891
 None
 1.14A 2qd2A-4o9xA:
undetectable		 2qd2A-4o9xA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Xanthobacter
autotrophicus) 		PF03480
(DctP) 		4 LEU A  51
ARG A 256
SER A  30
VAL A 138
 None
 1.20A 2qd2A-4ovrA:
undetectable		 2qd2A-4ovrA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfm 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE

(Shewanella
benthica) 		PF00701
(DHDPS) 		4 LEU A 239
ARG A 290
SER A   5
MET A 217
 None
 1.14A 2qd2A-4pfmA:
undetectable		 2qd2A-4pfmA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pgh CAFFEIC ACID
O-METHYLTRANSFERASE

(Sorghum bicolor) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 MET A 317
PRO A 150
SER A 136
VAL A 144
 None
 1.10A 2qd2A-4pghA:
2.3		 2qd2A-4pghA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pp1 LIGHT CHAIN OF FAB
FRAGMENT OF MAB 5H8
HEAVY CHAIN OF FAB
FRAGMENT OF MAB 5H8

(Mus musculus;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		4 MET C 174
LEU C 135
SER D 185
VAL C 158
 None
 0.87A 2qd2A-4pp1C:
undetectable		 2qd2A-4pp1C:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qo5 HYPOTHETICAL
MULTIHEME PROTEIN

(Ignicoccus
hospitalis) 		PF13435
(Cytochrome_C554)
PF13447
(Multi-haem_cyto) 		4 LEU A 113
PRO A  76
VAL A 103
MET A  71
 None
HEC  A 603 (-3.7A)
None
HEC  A 603 ( 2.4A)
 1.21A 2qd2A-4qo5A:
undetectable		 2qd2A-4qo5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvw ZNUD

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 LEU A 131
ARG A 358
SER A 482
VAL A 410
 None
 1.19A 2qd2A-4rvwA:
undetectable		 2qd2A-4rvwA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u33 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00128
(Alpha-amylase)
PF11896
(DUF3416) 		4 MET A 527
LEU A 523
ARG A 473
PRO A 495
 None
 1.10A 2qd2A-4u33A:
undetectable		 2qd2A-4u33A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w82 FATTY ACID SYNTHASE

(Homo sapiens) 		PF00107
(ADH_zinc_N) 		4 LEU A1628
PRO A1649
SER A1653
VAL A1636
 None
 1.19A 2qd2A-4w82A:
2.1		 2qd2A-4w82A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xbz EVDO1

(Micromonospora
carbonacea) 		PF05721
(PhyH) 		4 LEU A 220
ARG A 156
PRO A 251
VAL A 245
 None
 1.07A 2qd2A-4xbzA:
undetectable		 2qd2A-4xbzA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xoh DIVISION MAL FOUTUE
1 PROTEIN

(Schizosaccharomyces
pombe) 		no annotation 4 MET C 301
LEU C 249
ARG C 215
VAL C 226
 None
 1.20A 2qd2A-4xohC:
undetectable		 2qd2A-4xohC:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4r BIFUNCTIONAL
LYSINE-SPECIFIC
DEMETHYLASE AND
HISTIDYL-HYDROXYLASE
NO66

(Homo sapiens) 		PF08007
(Cupin_4) 		4 MET A 538
LEU A 587
SER A 198
VAL A 559
 None
 0.82A 2qd2A-4y4rA:
undetectable		 2qd2A-4y4rA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeb FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 3

(Mus musculus) 		PF13855
(LRR_8) 		4 MET B 333
ARG B 317
PRO B 337
VAL B 340
 None
 1.09A 2qd2A-4yebB:
undetectable		 2qd2A-4yebB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yoo RETINOBLASTOMA-LIKE
PROTEIN
1,RETINOBLASTOMA-LIK
E PROTEIN 1

(Homo sapiens) 		PF01857
(RB_B)
PF01858
(RB_A) 		4 MET A 835
LEU A 828
ARG A 802
SER A 572
 None
 1.03A 2qd2A-4yooA:
undetectable		 2qd2A-4yooA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhj MG-CHELATASE SUBUNIT
CHLH

(Synechocystis
sp. PCC 6803) 		PF02514
(CobN-Mg_chel)
PF11965
(DUF3479) 		4 LEU A1021
ARG A1073
SER A1135
VAL A1087
 None
 1.14A 2qd2A-4zhjA:
4.9		 2qd2A-4zhjA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esa ANTI-HCV E2
GLYCOPROTEIN FAB
HEAVY CHAIN
ANTI-HCV E2
GLYCOPROTEIN FAB
LIGHT CHAIN

(Homo sapiens;
Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		4 MET B 174
LEU B 135
SER A 184
VAL B 158
 None
 0.81A 2qd2A-5esaB:
undetectable		 2qd2A-5esaB:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f2h UNCHARACTERIZED
PROTEIN

(Bacillus cereus) 		PF02230
(Abhydrolase_2) 		4 LEU A  81
ARG A 106
SER A  53
MET A  62
 None
 1.05A 2qd2A-5f2hA:
4.7		 2qd2A-5f2hA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gn5 GLYCEROL KINASE

(Trypanosoma
brucei) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 MET A 263
LEU A 456
PRO A 444
MET A 446
 None
 1.13A 2qd2A-5gn5A:
undetectable		 2qd2A-5gn5A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB

(Mus musculus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 LEU A 288
PRO A 746
SER A 664
VAL A 394
 None
 1.19A 2qd2A-5hjrA:
undetectable		 2qd2A-5hjrA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5l BACTERIOPHYTOCHROME
PROTEIN

(Agrobacterium
fabrum) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 ARG A 244
PRO A 215
SER A 286
MET A 263
 BLA  A 601 (-3.0A)
None
None
None
 1.04A 2qd2A-5i5lA:
undetectable		 2qd2A-5i5lA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip7 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3

(Saccharomyces
cerevisiae) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		4 LEU C 155
ARG C  66
PRO C 132
VAL C 142
 None
 0.92A 2qd2A-5ip7C:
undetectable		 2qd2A-5ip7C:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk6 PHENYLALANINE-4-HYDR
OXYLASE

(Dictyostelium
discoideum) 		PF00351
(Biopterin_H) 		4 LEU A 130
ARG A 147
PRO A 260
SER A 261
 None
 1.18A 2qd2A-5jk6A:
undetectable		 2qd2A-5jk6A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jry NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans) 		PF00171
(Aldedh) 		4 LEU A 105
ARG A  79
SER A 151
VAL A 184
 None
None
NDP  A 500 (-4.7A)
None
 1.18A 2qd2A-5jryA:
2.8		 2qd2A-5jryA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens) 		PF03538
(VRP1) 		4 ARG A2512
PRO A2420
VAL A2417
MET A2454
 None
 1.06A 2qd2A-5lkiA:
undetectable		 2qd2A-5lkiA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN

(Mycolicibacterium
smegmatis) 		no annotation 4 MET B  50
LEU B  54
PRO B 258
VAL B 255
 None
 1.01A 2qd2A-5op0B:
undetectable		 2qd2A-5op0B:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ow6 VP1

(Cucumber mosaic
virus) 		PF00760
(Cucumo_coat) 		4 MET A 180
LEU A  92
SER A 132
VAL A 125
 None
 1.03A 2qd2A-5ow6A:
undetectable		 2qd2A-5ow6A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tu4 PAGF
PRENYLTRANSFERASE

(Planktothrix
agardhii) 		no annotation 4 LEU A 289
ARG A 283
PRO A 214
SER A 218
 None
 1.09A 2qd2A-5tu4A:
undetectable		 2qd2A-5tu4A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX

(unidentified) 		no annotation 4 ARG A 203
PRO A 263
SER A 265
VAL A 211
 None
 1.14A 2qd2A-5vqdA:
3.4		 2qd2A-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x0y TRANSCRIPTION
REGULATORY PROTEIN
SNF2

(Saccharomyces
cerevisiae) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		4 LEU O 942
ARG O 684
PRO O 989
VAL O 747
 None
 0.99A 2qd2A-5x0yO:
2.5		 2qd2A-5x0yO:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, HEAVY CHAIN
FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 MET L 175
LEU L 136
SER H 178
VAL L 159
 None
 1.00A 2qd2A-5xqwL:
undetectable		 2qd2A-5xqwL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5k NETRIN RECEPTOR DCC

(Rattus
norvegicus) 		no annotation 4 LEU A  81
PRO A  46
SER A 129
VAL A 134
 None
 1.20A 2qd2A-5z5kA:
undetectable		 2qd2A-5z5kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 MET L 175
LEU L 136
SER H 178
VAL L 159
 None
 0.95A 2qd2A-6bb4L:
undetectable		 2qd2A-6bb4L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c08 ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 MET B 178
LEU B 139
SER A 184
VAL B 162
 None
 0.95A 2qd2A-6c08B:
undetectable		 2qd2A-6c08B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4n PSEUDOPALINE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		no annotation 4 MET A 259
LEU A 316
SER A 267
VAL A 214
 None
 1.21A 2qd2A-6c4nA:
undetectable		 2qd2A-6c4nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Moorella
thermoacetica) 		no annotation 4 LEU A 802
ARG A 854
PRO A 703
SER A 693
 None
 1.13A 2qd2A-6cipA:
undetectable		 2qd2A-6cipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 LEU A1137
PRO A1025
VAL A1022
MET A1453
 None
 1.12A 2qd2A-6fb3A:
undetectable		 2qd2A-6fb3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g43 PUTATIVE MAJOR
CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus) 		no annotation 4 MET A 334
LEU A 349
ARG A 101
SER A 378
 None
 0.88A 2qd2A-6g43A:
undetectable		 2qd2A-6g43A:
undetectable