SIMILAR PATTERNS OF AMINO ACIDS FOR 2QBN_A_CAMA442

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A

(Ruminiclostridium
thermocellum) 		PF00963
(Cohesin) 		4 VAL A 105
VAL A  13
ASP A  11
VAL A 144
 None
 0.92A 2qbnA-1aohA:
undetectable		 2qbnA-1aohA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cwv INVASIN

(Yersinia
pseudotuberculosis) 		PF02369
(Big_1)
PF07979
(Intimin_C)
PF09134
(Invasin_D3) 		4 VAL A 577
VAL A 509
ASP A 512
VAL A 524
 None
 0.99A 2qbnA-1cwvA:
0.0		 2qbnA-1cwvA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1exs BETA-LACTOGLOBULIN

(Sus scrofa) 		PF00061
(Lipocalin) 		4 PHE A 136
THR A  21
VAL A 118
VAL A  26
 None
 1.01A 2qbnA-1exsA:
0.0		 2qbnA-1exsA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fwx NITROUS OXIDE
REDUCTASE

(Paracoccus
denitrificans) 		PF13473
(Cupredoxin_1) 		4 PHE A 549
TYR A 533
VAL A 487
VAL A 489
 None
 0.90A 2qbnA-1fwxA:
0.0		 2qbnA-1fwxA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7j PROTEIN YCIO

(Escherichia
coli) 		PF01300
(Sua5_yciO_yrdC) 		4 THR A 118
VAL A 195
ASP A 186
VAL A 184
 None
 0.94A 2qbnA-1k7jA:
undetectable		 2qbnA-1k7jA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lo9 4-HYDROXYBENZOYL-COA
THIOESTERASE

(Pseudomonas sp.
CBS3) 		no annotation 4 PHE A  39
TYR A  38
VAL A  93
VAL A 132
 None
 0.96A 2qbnA-1lo9A:
undetectable		 2qbnA-1lo9A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		4 TYR A 812
VAL A 689
VAL A 674
VAL A 675
 None
 0.95A 2qbnA-1no7A:
0.0		 2qbnA-1no7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o0e ERVATAMIN C

(Tabernaemontana
divaricata) 		PF00112
(Peptidase_C1) 		4 TYR A  72
THR A  33
VAL A 130
VAL A 111
 None
 0.93A 2qbnA-1o0eA:
undetectable		 2qbnA-1o0eA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5z FOLYLPOLYGLUTAMATE
SYNTHASE/DIHYDROFOLA
TE SYNTHASE

(Thermotoga
maritima) 		PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 TYR A 242
VAL A 196
VAL A  58
VAL A  54
 None
 1.00A 2qbnA-1o5zA:
0.0		 2qbnA-1o5zA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		4 PHE A 332
VAL A 408
VAL A 381
VAL A 388
 None
 0.00A 2qbnA-1q5aA:
undetectable		 2qbnA-1q5aA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkr AZURIN-I

(Achromobacter
xylosoxidans) 		PF00127
(Copper-bind) 		4 VAL A  49
VAL A  95
ASP A  93
VAL A  31
 None
 1.03A 2qbnA-1rkrA:
undetectable		 2qbnA-1rkrA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Thermotoga
maritima) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 THR A 109
VAL A 175
ASP A 177
VAL A 114
 None
 1.02A 2qbnA-1vkzA:
undetectable		 2qbnA-1vkzA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfi UNKNOWN PROTEIN

(Arabidopsis
thaliana) 		PF01937
(DUF89) 		4 THR A  25
VAL A 347
VAL A 359
VAL A 196
 None
 0.91A 2qbnA-1xfiA:
undetectable		 2qbnA-1xfiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9u PUTATIVE IRON
BINDING PROTEIN

(Bordetella
pertussis) 		PF13343
(SBP_bac_6) 		4 VAL A 167
VAL A 316
ASP A 322
VAL A 319
 None
 0.84A 2qbnA-1y9uA:
undetectable		 2qbnA-1y9uA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2

(Bacillus
anthracis) 		PF01510
(Amidase_2) 		4 TYR A 101
VAL A 109
VAL A  28
VAL A  89
 None
 1.02A 2qbnA-1yb0A:
undetectable		 2qbnA-1yb0A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0n 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-1 SUBUNIT

(Rattus
norvegicus) 		PF16561
(AMPK1_CBM) 		4 PHE A 127
THR A  85
VAL A 162
ASP A 136
 None
 0.98A 2qbnA-1z0nA:
undetectable		 2qbnA-1z0nA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z34 PURINE NUCLEOSIDE
PHOSPHORYLASE

(Trichomonas
vaginalis) 		PF01048
(PNP_UDP_1) 		4 PHE A  12
TYR A  80
VAL A  42
ASP A  11
 None
 1.00A 2qbnA-1z34A:
undetectable		 2qbnA-1z34A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zit TRANSCRIPTIONAL
REGULATOR (NTRC
FAMILY)

(Aquifex
aeolicus) 		PF00072
(Response_reg) 		4 VAL A 106
VAL A   6
ASP A   8
VAL A  50
 None
 0.93A 2qbnA-1zitA:
undetectable		 2qbnA-1zitA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zxu AT5G01750 PROTEIN

(Arabidopsis
thaliana) 		PF04525
(LOR) 		4 TYR A 117
VAL A 204
VAL A 159
VAL A 148
 None
 0.91A 2qbnA-1zxuA:
undetectable		 2qbnA-1zxuA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3d MODULATOR OF DRUG
ACTIVITY B

(Escherichia
coli) 		PF02525
(Flavodoxin_2) 		4 PHE A 177
THR A 135
VAL A 188
VAL A  38
 None
FAD  A1205 (-3.7A)
FAD  A1205 ( 4.6A)
None
 1.03A 2qbnA-2b3dA:
undetectable		 2qbnA-2b3dA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkh 3-HYDROXYBENZOATE
HYDROXYLASE

(Comamonas
testosteroni) 		PF01494
(FAD_binding_3)
PF07976
(Phe_hydrox_dim) 		4 THR A 442
VAL A 104
ASP A 125
VAL A 123
 None
 0.86A 2qbnA-2dkhA:
undetectable		 2qbnA-2dkhA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gk3 PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF07090
(GATase1_like) 		4 TYR A 186
VAL A 190
VAL A 197
VAL A 208
 None
 0.87A 2qbnA-2gk3A:
undetectable		 2qbnA-2gk3A:
21.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 PHE A  87
TYR A  96
THR A 101
VAL A 295
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.6A)
 0.91A 2qbnA-2m56A:
69.0		 2qbnA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		6 PHE A  87
TYR A  96
THR A 101
VAL A 295
ASP A 297
VAL A 396
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.6A)
HEM  A 501 (-2.8A)
None
 0.29A 2qbnA-2m56A:
69.0		 2qbnA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		5 THR A 101
VAL A 247
VAL A 295
ASP A 297
VAL A 396
 HEM  A 501 (-2.9A)
None
HEM  A 501 (-4.6A)
HEM  A 501 (-2.8A)
None
 1.44A 2qbnA-2m56A:
69.0		 2qbnA-2m56A:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C

(Sulfurisphaera
tokodaii) 		PF01967
(MoaC) 		4 THR A  60
VAL A 100
VAL A  21
VAL A 140
 None
 0.97A 2qbnA-2ohdA:
undetectable		 2qbnA-2ohdA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pns ERVATAMIN-C, A
PAPAIN-LIKE PLANT
CYSTEINE PROTEASE

(Tabernaemontana
divaricata) 		PF00112
(Peptidase_C1) 		4 TYR A  72
THR A  33
VAL A 130
VAL A 111
 None
 0.93A 2qbnA-2pnsA:
undetectable		 2qbnA-2pnsA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvs PANCREATIC
LIPASE-RELATED
PROTEIN 2

(Homo sapiens) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 PHE A 297
VAL A 389
VAL A 422
VAL A 342
 None
 0.94A 2qbnA-2pvsA:
undetectable		 2qbnA-2pvsA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 TYR A 444
VAL A 572
VAL A 392
VAL A 363
 None
 0.94A 2qbnA-2qzpA:
undetectable		 2qbnA-2qzpA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4b RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 THR A 909
VAL A 808
VAL A 857
VAL A 851
 None
 1.03A 2qbnA-2r4bA:
undetectable		 2qbnA-2r4bA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rh7 GREEN FLUORESCENT
PROTEIN

(Renilla
reniformis) 		PF01353
(GFP) 		4 TYR A 181
THR A 179
VAL A  63
VAL A 122
 None
None
CRO  A  66 ( 3.9A)
None
 0.97A 2qbnA-2rh7A:
undetectable		 2qbnA-2rh7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rif CONSERVED PROTEIN
WITH 2 CBS DOMAINS

(Pyrobaculum
aerophilum) 		PF00571
(CBS) 		4 VAL A  86
VAL A 103
ASP A  82
VAL A  80
 None
 1.01A 2qbnA-2rifA:
undetectable		 2qbnA-2rifA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwb COMPLEMENT C3B
ALPHA' CHAIN

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 VAL B 828
VAL B 903
ASP B 901
VAL B 890
 None
 0.88A 2qbnA-2xwbB:
undetectable		 2qbnA-2xwbB:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anw PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermococcus
kodakarensis) 		PF05916
(Sld5) 		4 VAL B  40
VAL B  25
ASP B  23
VAL B  10
 None
 0.97A 2qbnA-3anwB:
undetectable		 2qbnA-3anwB:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bcn ERVATAMIN-A

(Tabernaemontana
divaricata) 		PF00112
(Peptidase_C1) 		4 TYR A  72
THR A  33
VAL A 130
VAL A 111
 None
 1.04A 2qbnA-3bcnA:
undetectable		 2qbnA-3bcnA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be8 NEUROLIGIN-4,
X-LINKED

(Homo sapiens) 		PF00135
(COesterase) 		4 VAL A 441
VAL A 384
ASP A 388
VAL A 390
 None
 0.86A 2qbnA-3be8A:
undetectable		 2qbnA-3be8A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da2 CARBONIC ANHYDRASE
13

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 PHE A 132
VAL A 201
VAL A 144
VAL A 208
 4MD  A 401 (-4.6A)
4MD  A 401 ( 4.2A)
4MD  A 401 ( 4.4A)
None
 0.99A 2qbnA-3da2A:
undetectable		 2qbnA-3da2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h43 PROTEASOME-ACTIVATIN
G NUCLEOTIDASE

(Methanocaldococcus
jannaschii) 		no annotation 4 VAL A 120
VAL A  97
ASP A  99
VAL A 108
 None
 0.98A 2qbnA-3h43A:
undetectable		 2qbnA-3h43A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8f CYTOSOL
AMINOPEPTIDASE

(Pseudomonas
putida) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 TYR A 127
VAL A 109
VAL A  31
ASP A 113
 None
 1.03A 2qbnA-3h8fA:
undetectable		 2qbnA-3h8fA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Streptococcus
pneumoniae) 		PF01380
(SIS) 		5 PHE A  88
TYR A  81
VAL A 191
VAL A 111
VAL A 113
 None
 1.39A 2qbnA-3i0zA:
undetectable		 2qbnA-3i0zA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igz COFACTOR-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Leishmania
mexicana) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 TYR B 163
THR B 177
VAL B 159
VAL B 259
 None
 1.00A 2qbnA-3igzB:
undetectable		 2qbnA-3igzB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb5 MAJOR CAPSID PROTEIN

(Propionibacterium
virus PA6) 		no annotation 4 PHE A 184
VAL A 161
VAL A 178
VAL A 243
 None
 0.98A 2qbnA-3jb5A:
undetectable		 2qbnA-3jb5A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE

(Listeria
monocytogenes) 		PF01170
(UPF0020)
PF02926
(THUMP) 		4 THR A 293
VAL A 326
VAL A 300
VAL A 335
 None
 0.85A 2qbnA-3k0bA:
undetectable		 2qbnA-3k0bA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ki8 BETA
UREIDOPROPIONASE
(BETA-ALANINE
SYNTHASE)

(Pyrococcus
abyssi) 		PF00795
(CN_hydrolase) 		4 PHE A 138
VAL A  38
VAL A 165
VAL A 141
 None
 0.95A 2qbnA-3ki8A:
undetectable		 2qbnA-3ki8A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lzb EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 THR A 879
VAL A 778
VAL A 827
VAL A 821
 None
 0.97A 2qbnA-3lzbA:
undetectable		 2qbnA-3lzbA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzq BIOSYNTHETIC
ARGININE
DECARBOXYLASE

(Escherichia
coli) 		PF02784
(Orn_Arg_deC_N) 		4 PHE A  92
VAL A  76
VAL A 585
VAL A 597
 None
 0.91A 2qbnA-3nzqA:
undetectable		 2qbnA-3nzqA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzr 2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE

(Aliivibrio
fischeri) 		PF07071
(KDGP_aldolase) 		4 TYR A  44
VAL A  21
VAL A  65
VAL A  37
 None
 0.83A 2qbnA-3nzrA:
undetectable		 2qbnA-3nzrA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1

(Vibrio cholerae) 		PF01048
(PNP_UDP_1) 		4 PHE A  26
TYR A  94
VAL A  56
ASP A  25
 None
 0.97A 2qbnA-3of3A:
undetectable		 2qbnA-3of3A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oks 4-AMINOBUTYRATE
TRANSAMINASE

(Mycolicibacterium
smegmatis) 		PF00202
(Aminotran_3) 		4 THR A 158
VAL A 135
VAL A 289
VAL A 303
 None
 1.02A 2qbnA-3oksA:
undetectable		 2qbnA-3oksA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oks 4-AMINOBUTYRATE
TRANSAMINASE

(Mycolicibacterium
smegmatis) 		PF00202
(Aminotran_3) 		4 THR A 161
VAL A 135
VAL A 289
VAL A 303
 None
 0.88A 2qbnA-3oksA:
undetectable		 2qbnA-3oksA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE

(Mycolicibacterium
smegmatis) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 THR A 327
VAL A  20
VAL A   6
VAL A  36
 None
 1.00A 2qbnA-3p2yA:
undetectable		 2qbnA-3p2yA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q8n 4-AMINOBUTYRATE
TRANSAMINASE

(Mycolicibacterium
smegmatis) 		PF00202
(Aminotran_3) 		4 THR A 168
VAL A 142
VAL A 290
VAL A 304
 None
 0.86A 2qbnA-3q8nA:
undetectable		 2qbnA-3q8nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd8 PROBABLE
BACTERIOFERRITIN
BFRB

(Mycobacterium
tuberculosis) 		PF00210
(Ferritin) 		4 PHE A  48
TYR A  29
VAL A 136
VAL A 143
 None
 0.90A 2qbnA-3qd8A:
undetectable		 2qbnA-3qd8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdn PUTATIVE THIOREDOXIN
PROTEIN

(Salmonella
enterica) 		PF00085
(Thioredoxin)
PF14559
(TPR_19)
PF14561
(TPR_20) 		4 PHE A  56
TYR A  52
VAL A  44
VAL A  81
 None
 0.95A 2qbnA-3qdnA:
undetectable		 2qbnA-3qdnA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnq PTS SYSTEM,
CELLOBIOSE-SPECIFIC
IIC COMPONENT

(Bacillus cereus) 		PF02378
(PTS_EIIC) 		4 PHE A 288
VAL A 358
VAL A 238
VAL A 235
 None
 0.91A 2qbnA-3qnqA:
undetectable		 2qbnA-3qnqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE

(uncultured
organism) 		PF01042
(Ribonuc_L-PSP) 		4 PHE A  98
VAL A  56
VAL A  90
VAL A  93
 None
 1.00A 2qbnA-3r0pA:
undetectable		 2qbnA-3r0pA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rip GAMMA-TUBULIN
COMPLEX COMPONENT 4

(Homo sapiens) 		PF04130
(Spc97_Spc98) 		4 PHE A  55
VAL A 168
VAL A 138
VAL A 139
 None
 0.97A 2qbnA-3ripA:
undetectable		 2qbnA-3ripA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty7 PUTATIVE ALDEHYDE
DEHYDROGENASE
SAV2122

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		4 TYR A 390
VAL A 411
ASP A 256
VAL A 258
 None
 1.03A 2qbnA-3ty7A:
undetectable		 2qbnA-3ty7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w34 URIDINE KINASE

(Thermus
thermophilus) 		PF00485
(PRK) 		4 PHE A  65
TYR A  43
VAL A 165
VAL A 173
 None
CTN  A 301 (-4.1A)
CTN  A 301 ( 4.8A)
None
 0.98A 2qbnA-3w34A:
undetectable		 2qbnA-3w34A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CMR4

(Archaeoglobus
fulgidus) 		PF03787
(RAMPs) 		4 PHE C  11
VAL C 318
VAL C 123
VAL C 297
 None
 0.90A 2qbnA-3x1lC:
undetectable		 2qbnA-3x1lC:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aut DECAPRENYL-PHOSPHORY
L-BETA-D-RIBOFURANOS
E-2-OXIDOREDUCTASE

(Mycolicibacterium
smegmatis) 		PF01565
(FAD_binding_4)
PF04030
(ALO) 		4 VAL A  97
VAL A 103
ASP A 100
VAL A 130
 None
 1.03A 2qbnA-4autA:
undetectable		 2qbnA-4autA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bin N-ACETYLMURAMOYL-L-A
LANINE AMIDASE AMIC

(Escherichia
coli) 		PF01520
(Amidase_3)
PF11741
(AMIN) 		4 PHE A 115
VAL A 111
VAL A  39
VAL A  52
 None
 0.98A 2qbnA-4binA:
undetectable		 2qbnA-4binA:
22.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		5 TYR A  98
THR A 103
VAL A 303
ASP A 305
VAL A 404
 None
GOL  A1419 (-3.8A)
GOL  A1419 (-3.9A)
HEM  A1418 (-2.7A)
GOL  A1419 (-3.5A)
 0.53A 2qbnA-4c9mA:
58.4		 2qbnA-4c9mA:
44.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d3y LEGUMAIN

(Cricetulus
griseus) 		PF01650
(Peptidase_C13) 		4 TYR A 149
THR A 151
VAL A 240
VAL A 100
 None
SNN  A 152 ( 3.8A)
None
None
 1.00A 2qbnA-4d3yA:
undetectable		 2qbnA-4d3yA:
19.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 PHE A  87
THR A 101
VAL A 301
VAL A 402
 None
HEM  A 501 ( 4.8A)
PEG  A 502 ( 4.5A)
None
 0.83A 2qbnA-4dxyA:
51.5		 2qbnA-4dxyA:
46.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e0t CYCLIC DIPEPTIDE
N-PRENYLTRANSFERASE

(Aspergillus
fumigatus) 		PF11991
(Trp_DMAT) 		4 TYR A 105
THR A 203
VAL A 151
VAL A  93
 None
EDO  A 603 ( 4.0A)
None
None
 1.03A 2qbnA-4e0tA:
undetectable		 2qbnA-4e0tA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e84 D-BETA-D-HEPTOSE
7-PHOSPHATE KINASE

(Burkholderia
cenocepacia) 		PF00294
(PfkB) 		4 PHE A 315
THR A 275
VAL A   7
VAL A   8
 None
 1.02A 2qbnA-4e84A:
undetectable		 2qbnA-4e84A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2b SECRETED EFFECTOR
PROTEIN SSEI

(Salmonella
enterica) 		PF15645
(Tox-PLDMTX) 		4 VAL A 257
VAL A 220
ASP A 227
VAL A 229
 None
 1.02A 2qbnA-4g2bA:
undetectable		 2qbnA-4g2bA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hgv FUMARATE HYDRATASE
CLASS II

(Sinorhizobium
meliloti) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 VAL A 464
VAL A 450
ASP A 457
VAL A 455
 None
 1.02A 2qbnA-4hgvA:
undetectable		 2qbnA-4hgvA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN

(Pseudomonas) 		PF01804
(Penicil_amidase) 		4 THR B  13
VAL B   6
VAL B 474
ASP B 476
 None
 0.97A 2qbnA-4hstB:
undetectable		 2qbnA-4hstB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kg7 PEPTIDASE S8 AND
S53, SUBTILISIN,
KEXIN, SEDOLISIN

(Mycolicibacterium
smegmatis) 		PF00082
(Peptidase_S8) 		4 VAL A 354
VAL A 231
ASP A 229
VAL A 197
 None
 0.97A 2qbnA-4kg7A:
undetectable		 2qbnA-4kg7A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE

(Rhodotorula
mucilaginosa) 		PF13561
(adh_short_C2) 		4 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.83A 2qbnA-4o0lA:
undetectable		 2qbnA-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pve POLLEN ALLERGEN PHL
P 4.0202

(Phleum pratense) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 PHE A 487
VAL A 216
VAL A 104
VAL A  81
 None
None
None
FAD  A 601 (-4.2A)
 1.01A 2qbnA-4pveA:
undetectable		 2qbnA-4pveA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 PHE A  93
VAL A 201
VAL A 149
VAL A 153
 None
 0.97A 2qbnA-4q2cA:
undetectable		 2qbnA-4q2cA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1890

(Streptococcus
agalactiae) 		PF03610
(EIIA-man) 		4 TYR A  80
VAL A  72
VAL A  60
VAL A  87
 None
 0.73A 2qbnA-4tkzA:
undetectable		 2qbnA-4tkzA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wr3 ALANINE RACEMASE,
BIOSYNTHETIC

(Escherichia
coli) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 VAL A 269
VAL A 290
ASP A 320
VAL A 322
 None
 0.99A 2qbnA-4wr3A:
undetectable		 2qbnA-4wr3A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis) 		PF03060
(NMO) 		4 THR A 195
VAL A 175
VAL A 220
VAL A 186
 None
 1.00A 2qbnA-4z9rA:
undetectable		 2qbnA-4z9rA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb0 UNIVERSAL STRESS
PROTEIN E

(Escherichia
coli) 		PF00582
(Usp) 		4 TYR A 304
THR A 306
VAL A 112
VAL A 142
 None
 1.00A 2qbnA-5cb0A:
undetectable		 2qbnA-5cb0A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb0 UNIVERSAL STRESS
PROTEIN E

(Escherichia
coli) 		PF00582
(Usp) 		4 TYR A 304
THR A 306
VAL A 142
VAL A 298
 None
 0.99A 2qbnA-5cb0A:
undetectable		 2qbnA-5cb0A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmh UNCHARACTERIZED
PROTEIN CONSERVED IN
BACTERIA

(Cupriavidus
necator) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		5 PHE A  98
TYR A  94
THR A 231
VAL A 177
VAL A 166
 None
 1.40A 2qbnA-5dmhA:
undetectable		 2qbnA-5dmhA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 THR A1019
VAL A 997
VAL A1012
VAL A 978
 None
 0.86A 2qbnA-5dotA:
undetectable		 2qbnA-5dotA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eoe BETA-LACTAMASE

(Pseudomonas
aeruginosa) 		PF13354
(Beta-lactamase2) 		4 TYR A 255
THR A 174
VAL A  42
VAL A 251
 None
 1.03A 2qbnA-5eoeA:
undetectable		 2qbnA-5eoeA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5erd DESMOGLEIN-2

(Homo sapiens) 		PF00028
(Cadherin) 		4 TYR A 319
VAL A 303
VAL A 246
VAL A 223
 None
 0.99A 2qbnA-5erdA:
undetectable		 2qbnA-5erdA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hee PUTATIVE
UNCHARACTERIZED
PROTEIN, TK2203
PROTEIN

(Thermococcus
kodakarensis) 		PF02900
(LigB) 		4 VAL A 157
VAL A 134
ASP A  82
VAL A  43
 None
 0.81A 2qbnA-5heeA:
undetectable		 2qbnA-5heeA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inw PUTATIVE
ANGIOTENSINOGEN

(Lampetra
fluviatilis) 		PF00079
(Serpin) 		4 TYR A 301
THR A 405
VAL A 309
VAL A 297
 None
 0.97A 2qbnA-5inwA:
undetectable		 2qbnA-5inwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN

(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		PF00079
(Serpin)
PF00079
(Serpin) 		4 TYR A 301
THR A 405
VAL C 432
VAL C 442
 None
 0.71A 2qbnA-5inwA:
undetectable		 2qbnA-5inwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iwd DNA POLYMERASE
PROCESSIVITY FACTOR

(Human
betaherpesvirus
5) 		PF03325
(Herpes_PAP) 		4 TYR A  20
THR A  94
VAL A  40
VAL A 104
 None
 0.90A 2qbnA-5iwdA:
undetectable		 2qbnA-5iwdA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j9z EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 THR A 903
VAL A 802
VAL A 851
VAL A 845
 None
 0.94A 2qbnA-5j9zA:
undetectable		 2qbnA-5j9zA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF01821
(ANATO)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 VAL B 854
VAL B 927
ASP B 925
VAL B 913
 None
 0.92A 2qbnA-5jpnB:
undetectable		 2qbnA-5jpnB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jtw COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 VAL B 854
VAL B 927
ASP B 925
VAL B 913
 None
 1.02A 2qbnA-5jtwB:
undetectable		 2qbnA-5jtwB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis) 		no annotation 4 THR A  57
VAL A 178
VAL A 263
VAL A  45
 NA  A 502 ( 4.8A)
NA  A 502 (-4.2A)
None
None
 0.96A 2qbnA-5nvaA:
undetectable		 2qbnA-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oms CYTOCHROME P450

(Amycolatopsis
sp. ATCC 39116) 		no annotation 4 PHE A  63
THR A 315
VAL A 309
VAL A  53
 None
 0.87A 2qbnA-5omsA:
38.8		 2qbnA-5omsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swj PROBABLE ATP
SYNTHASE SPAL/MXIB

(Shigella
flexneri) 		PF00006
(ATP-synt_ab) 		4 PHE A 106
THR A 109
VAL A 102
VAL A  96
 None
 0.93A 2qbnA-5swjA:
undetectable		 2qbnA-5swjA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5syd AZURIN, CHIMERIC
CONSTRUCT

(Pseudomonas
aeruginosa) 		PF00127
(Copper-bind) 		4 VAL A   9
VAL A  55
ASP A  53
VAL A 124
 None
 1.02A 2qbnA-5sydA:
undetectable		 2qbnA-5sydA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wjd CG8481, ISOFORM B

(Drosophila
melanogaster) 		no annotation 4 PHE A 107
VAL A 114
ASP A 110
VAL A 115
 None
 1.01A 2qbnA-5wjdA:
undetectable		 2qbnA-5wjdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyj ACETYL-COA
ACETYLTRANSFERASE

(Saccharomyces
cerevisiae) 		no annotation 4 PHE B  51
VAL B 268
ASP B  50
VAL B 264
 None
 1.03A 2qbnA-5xyjB:
undetectable		 2qbnA-5xyjB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt7 -

(-) 		no annotation 4 VAL A  68
VAL A 114
ASP A 112
VAL A  50
 None
None
CA  A 202 ( 2.7A)
None
 0.98A 2qbnA-5yt7A:
undetectable		 2qbnA-5yt7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbi PEPTIDE ASPARAGINYL
LIGASE

(Viola
canadensis) 		no annotation 4 TYR A 162
THR A 164
VAL A 262
VAL A 114
 None
 1.01A 2qbnA-5zbiA:
undetectable		 2qbnA-5zbiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 4 TYR A 874
VAL A 813
VAL A 846
VAL A 867
 None
 0.97A 2qbnA-6f9nA:
undetectable		 2qbnA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g7x -

(-) 		no annotation 4 PHE A  12
TYR A  80
VAL A  42
ASP A  11
 None
 1.01A 2qbnA-6g7xA:
undetectable		 2qbnA-6g7xA:
undetectable