SIMILAR PATTERNS OF AMINO ACIDS FOR 2QBM_A_CAMA517_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5f PROTEIN (CARDOSIN A)
PROTEIN (CARDOSIN A)

(Cynara
cardunculus;
Cynara
cardunculus) 		PF00026
(Asp)
PF00026
(Asp) 		4 PHE A 213
TYR A 189
ASP A 215
ILE B 300
 None
 0.98A 2qbmA-1b5fA:
0.0		 2qbmA-1b5fA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN

(Propionibacterium
freudenreichii) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		4 THR A 259
THR A 327
ASP A 199
ILE A 238
 None
 0.94A 2qbmA-1e1cA:
0.0		 2qbmA-1e1cA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ehi D-ALANINE:D-LACTATE
LIGASE

(Leuconostoc
mesenteroides) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 PHE A  50
THR A 110
VAL A 101
ILE A   9
 None
 0.96A 2qbmA-1ehiA:
0.0		 2qbmA-1ehiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fng PROTEIN (MHC CLASS
II I-EK, BETA CHAIN)

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 PHE B 122
THR B 145
VAL B 129
ILE B 127
 None
 0.67A 2qbmA-1fngB:
undetectable		 2qbmA-1fngB:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ia5 POLYGALACTURONASE

(Aspergillus
aculeatus) 		PF00295
(Glyco_hydro_28) 		4 VAL A 220
THR A 221
VAL A 234
ILE A 236
 None
 0.92A 2qbmA-1ia5A:
undetectable		 2qbmA-1ia5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqt FPRA

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 PHE A 128
TYR A 132
THR A 168
VAL A 194
 None
 0.98A 2qbmA-1lqtA:
0.0		 2qbmA-1lqtA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpx ALPHA-AMINO ACID
ESTER HYDROLASE

(Xanthomonas
citri) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 0.98A 2qbmA-1mpxA:
0.0		 2qbmA-1mpxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqq ALPHA-D-GLUCURONIDAS
E

(Geobacillus
stearothermophilus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		4 PHE A 663
VAL A 518
VAL A 604
ILE A 608
 None
 0.97A 2qbmA-1mqqA:
0.0		 2qbmA-1mqqA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlq NUCLEOPLASMIN-LIKE
PROTEIN

(Drosophila
melanogaster) 		PF03066
(Nucleoplasmin) 		4 TYR A   7
VAL A  86
THR A  87
VAL A  51
 None
 0.96A 2qbmA-1nlqA:
undetectable		 2qbmA-1nlqA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nxj PROBABLE
S-ADENOSYLMETHIONINE
:2-DEMETHYLMENAQUINO
NE METHYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF03737
(RraA-like) 		4 THR A 135
VAL A 156
ASP A 145
ILE A  39
 None
 0.93A 2qbmA-1nxjA:
undetectable		 2qbmA-1nxjA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rjw ALCOHOL
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 THR A 104
VAL A 151
THR A 152
VAL A 159
 None
 0.97A 2qbmA-1rjwA:
undetectable		 2qbmA-1rjwA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ss4 GLYOXALASE FAMILY
PROTEIN

(Bacillus cereus) 		PF13669
(Glyoxalase_4) 		4 PHE A  26
VAL A  16
VAL A  12
ILE A  69
 None
 0.94A 2qbmA-1ss4A:
undetectable		 2qbmA-1ss4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmo TRIMETHYLAMINE
N-OXIDE REDUCTASE

(Shewanella
massilia) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		5 PHE A 524
VAL A 465
THR A 466
ASP A 520
ILE A 523
 None
None
None
2MD  A 799 (-3.4A)
None
 1.22A 2qbmA-1tmoA:
undetectable		 2qbmA-1tmoA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1umf CHORISMATE SYNTHASE

(Helicobacter
pylori) 		PF01264
(Chorismate_synt) 		4 PHE A 138
VAL A  63
VAL A  69
ILE A  79
 None
 0.96A 2qbmA-1umfA:
undetectable		 2qbmA-1umfA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upx HYDROXYLAMINE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF03063
(Prismane) 		4 TYR A 321
THR A 353
VAL A 257
ILE A 235
 None
 0.93A 2qbmA-1upxA:
undetectable		 2qbmA-1upxA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vdk FUMARATE HYDRATASE
CLASS II

(Thermus
thermophilus) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 THR A 170
VAL A 380
VAL A 295
ILE A 291
 None
 0.82A 2qbmA-1vdkA:
undetectable		 2qbmA-1vdkA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhc PUTATIVE KHG/KDPG
ALDOLASE

(Haemophilus
influenzae) 		PF01081
(Aldolase) 		4 PHE A  90
VAL A  18
ASP A  89
ILE A   8
 None
 0.82A 2qbmA-1vhcA:
undetectable		 2qbmA-1vhcA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1viw ALPHA-AMYLASE-INHIBI
TOR

(Phaseolus
vulgaris) 		PF00139
(Lectin_legB) 		4 PHE B  62
VAL B  98
THR B  99
VAL B 148
 None
 0.83A 2qbmA-1viwB:
undetectable		 2qbmA-1viwB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlh GELATION FACTOR

(Dictyostelium
discoideum) 		PF00630
(Filamin) 		4 PHE A 617
VAL A 645
THR A 644
ILE A 595
 None
 0.96A 2qbmA-1wlhA:
undetectable		 2qbmA-1wlhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc3 PUTATIVE
FRUCTOKINASE

(Bacillus
subtilis) 		PF00480
(ROK) 		4 PHE A  86
VAL A  41
VAL A  98
ILE A  55
 None
 0.92A 2qbmA-1xc3A:
undetectable		 2qbmA-1xc3A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yub RRNA
METHYLTRANSFERASE

(Streptococcus
pneumoniae) 		PF00398
(RrnaAD) 		4 THR A 134
THR A 107
VAL A 114
ILE A 122
 None
 0.96A 2qbmA-1yubA:
undetectable		 2qbmA-1yubA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yws PROTEIN YBL071W-A

(Saccharomyces
cerevisiae) 		PF05207
(zf-CSL) 		4 TYR A  66
THR A  22
VAL A  56
ILE A   9
 None
 0.88A 2qbmA-1ywsA:
undetectable		 2qbmA-1ywsA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2f EXOCYST COMPLEX
COMPONENT SEC15

(Drosophila
melanogaster) 		PF04091
(Sec15) 		4 PHE X 288
THR X 250
THR X 231
ILE X 225
 None
 0.95A 2qbmA-2a2fX:
undetectable		 2qbmA-2a2fX:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7h HEMOGLOBIN ALPHA
CHAIN

(Cerdocyon thous) 		PF00042
(Globin) 		4 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.87A 2qbmA-2b7hA:
undetectable		 2qbmA-2b7hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu9 HISTONE CHAPERONE
CIA1

(Schizosaccharomyces
pombe) 		PF04729
(ASF1_hist_chap) 		4 TYR A  22
VAL A 114
THR A  94
VAL A 141
 None
 0.97A 2qbmA-2cu9A:
undetectable		 2qbmA-2cu9A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ee9 FILAMIN-B

(Homo sapiens) 		PF00630
(Filamin) 		4 PHE A  25
THR A  33
VAL A  56
ILE A  23
 None
 0.94A 2qbmA-2ee9A:
undetectable		 2qbmA-2ee9A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eez ALANINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 THR A 315
THR A  19
VAL A   5
ILE A   3
 None
 0.98A 2qbmA-2eezA:
undetectable		 2qbmA-2eezA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL

(Rattus
norvegicus) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		5 THR A 176
VAL A 213
THR A 212
ASP A 270
ILE A 206
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
None
 1.16A 2qbmA-2f43A:
undetectable		 2qbmA-2f43A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2grm PRGX

(Enterococcus
faecalis) 		PF01381
(HTH_3) 		4 TYR A 254
VAL A 295
THR A 296
ILE A 283
 None
 0.89A 2qbmA-2grmA:
undetectable		 2qbmA-2grmA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h3g BIOSYNTHETIC PROTEIN

(Bacillus
anthracis) 		PF03309
(Pan_kinase) 		4 PHE X 130
THR X 151
VAL X 204
ILE X 227
 None
 0.94A 2qbmA-2h3gX:
undetectable		 2qbmA-2h3gX:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hey TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER 4

(Mus musculus) 		no annotation 4 PHE F 110
VAL F 156
VAL F  67
ILE F 168
 None
 0.98A 2qbmA-2heyF:
undetectable		 2qbmA-2heyF:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j66 BTRK

(Bacillus
circulans) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 PHE A 229
THR A 195
VAL A 249
THR A 248
 None
 0.72A 2qbmA-2j66A:
undetectable		 2qbmA-2j66A:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 PHE A  87
THR A 252
ASP A 297
ILE A 395
 CAM  A 502 (-4.6A)
HEM  A 501 (-3.4A)
HEM  A 501 (-2.8A)
None
 0.94A 2qbmA-2m56A:
69.2		 2qbmA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		7 PHE A  87
TYR A  96
THR A 101
VAL A 247
VAL A 295
ASP A 297
ILE A 395
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
None
HEM  A 501 (-4.6A)
HEM  A 501 (-2.8A)
None
 0.37A 2qbmA-2m56A:
69.2		 2qbmA-2m56A:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqm PROTEIN HNRNPL

(Rattus
norvegicus) 		PF00076
(RRM_1) 		4 TYR A 254
VAL A 207
THR A 204
VAL A 229
 None
 0.90A 2qbmA-2mqmA:
undetectable		 2qbmA-2mqmA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nna MHC CLASS II ANTIGEN

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 PHE B 122
THR B 145
VAL B 129
ILE B 127
 None
 0.85A 2qbmA-2nnaB:
undetectable		 2qbmA-2nnaB:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrr UVRABC SYSTEM
PROTEIN C

(Thermotoga
maritima) 		PF08459
(UvrC_HhH_N) 		4 THR A 376
VAL A 412
THR A 411
ASP A 405
 None
 0.97A 2qbmA-2nrrA:
undetectable		 2qbmA-2nrrA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrx UVRABC SYSTEM
PROTEIN C

(Thermotoga
maritima) 		PF08459
(UvrC_HhH_N) 		4 THR A 376
VAL A 412
THR A 411
ASP A 405
 None
 0.96A 2qbmA-2nrxA:
undetectable		 2qbmA-2nrxA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2of3 ZYG-9

(Caenorhabditis
elegans) 		no annotation 4 THR A 770
VAL A 813
THR A 812
ILE A 801
 None
 0.90A 2qbmA-2of3A:
undetectable		 2qbmA-2of3A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0k POLYCOMB PROTEIN
SCMH1

(Homo sapiens) 		PF02820
(MBT) 		4 PHE A  28
THR A  37
THR A 188
VAL A 222
 None
 0.95A 2qbmA-2p0kA:
undetectable		 2qbmA-2p0kA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfy PUTATIVE EXPORTED
PROTEIN

(Bordetella
pertussis) 		PF03480
(DctP) 		4 PHE A 172
TYR A 195
THR A 182
ILE A 177
 None
None
PCA  A 302 (-3.5A)
None
 0.97A 2qbmA-2pfyA:
undetectable		 2qbmA-2pfyA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2phc UNCHARACTERIZED
PROTEIN PH0987

(Pyrococcus
horikoshii) 		PF02682
(CT_C_D) 		4 THR B 168
VAL B 206
VAL B  90
ILE B 185
 None
 0.94A 2qbmA-2phcB:
undetectable		 2qbmA-2phcB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjb UNCHARACTERIZED
PROTEIN

(Shigella
flexneri) 		PF07063
(DUF1338) 		4 PHE A 333
THR A 299
VAL A 296
ILE A 260
 None
 0.96A 2qbmA-2rjbA:
undetectable		 2qbmA-2rjbA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd9 ALANINE RACEMASE

(Bacillus
anthracis) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 PHE A 320
VAL A 334
THR A 335
ILE A 311
 None
MLY  A 333 ( 3.1A)
None
None
 0.97A 2qbmA-2vd9A:
undetectable		 2qbmA-2vd9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w55 XANTHINE
DEHYDROGENASE

(Rhodobacter
capsulatus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 THR B  41
VAL B 264
ASP B 261
ILE B 265
 None
 0.93A 2qbmA-2w55B:
undetectable		 2qbmA-2w55B:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wan PULLULANASE

(Bacillus
acidopullulyticus) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 PHE A 699
THR A 916
VAL A 714
ILE A 710
 None
 0.86A 2qbmA-2wanA:
undetectable		 2qbmA-2wanA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnw ACTIVATED BY
TRANSCRIPTION FACTOR
SSRB

(Salmonella
enterica) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		4 PHE A 328
THR A 312
ASP A 330
ILE A 370
 None
 0.91A 2qbmA-2wnwA:
undetectable		 2qbmA-2wnwA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		4 PHE A 421
THR A 440
VAL A 320
ILE A 399
 None
 0.95A 2qbmA-2xdqA:
undetectable		 2qbmA-2xdqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yev CYTOCHROME C OXIDASE
POLYPEPTIDE I+III
CAA3-TYPE CYTOCHROME
OXIDASE SUBUNIT IV

(Thermus
thermophilus;
Thermus
thermophilus) 		PF00115
(COX1)
PF00510
(COX3)
no annotation 		4 THR A 294
VAL C  14
THR C  15
VAL A 626
 None
 0.95A 2qbmA-2yevA:
undetectable		 2qbmA-2yevA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak5 HEMOGLOBIN-BINDING
PROTEASE HBP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 VAL A 431
THR A 430
VAL A 403
ILE A 401
 None
 0.90A 2qbmA-3ak5A:
undetectable		 2qbmA-3ak5A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b89 16S RRNA METHYLASE

(Escherichia
coli) 		PF07091
(FmrO) 		4 THR A  84
VAL A  74
VAL A 139
ILE A 140
 None
 0.89A 2qbmA-3b89A:
undetectable		 2qbmA-3b89A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bx8 ENGINEERED HUMAN
LIPOCALIN 2

(Homo sapiens) 		PF00061
(Lipocalin) 		4 PHE A  27
THR A  54
THR A 136
VAL A 108
 None
1PE  A 179 ( 4.7A)
None
None
 0.97A 2qbmA-3bx8A:
undetectable		 2qbmA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bx8 ENGINEERED HUMAN
LIPOCALIN 2

(Homo sapiens) 		PF00061
(Lipocalin) 		5 PHE A  83
TYR A  56
THR A  54
VAL A 121
THR A 136
 None
None
1PE  A 179 ( 4.7A)
None
None
 1.05A 2qbmA-3bx8A:
undetectable		 2qbmA-3bx8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cji POLYPROTEIN

(Senecavirus A) 		no annotation 4 THR A  80
THR A 216
VAL A 237
ILE A 239
 None
 0.67A 2qbmA-3cjiA:
undetectable		 2qbmA-3cjiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f92 UBIQUITIN-CONJUGATIN
G ENZYME E2 K

(Homo sapiens) 		PF00179
(UQ_con)
PF00627
(UBA) 		4 TYR A  66
THR A 108
VAL A  29
ILE A  60
 None
 0.94A 2qbmA-3f92A:
undetectable		 2qbmA-3f92A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flo DNA POLYMERASE ALPHA
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF04042
(DNA_pol_E_B)
PF08418
(Pol_alpha_B_N) 		4 PHE A 531
VAL A 670
THR A 669
ILE A 526
 None
 0.97A 2qbmA-3floA:
undetectable		 2qbmA-3floA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gby UNCHARACTERIZED
PROTEIN CT1051

(Chlorobaculum
tepidum) 		PF00571
(CBS) 		4 VAL A   2
THR A   3
VAL A 112
ILE A 117
 None
 0.96A 2qbmA-3gbyA:
undetectable		 2qbmA-3gbyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gfo COBALT IMPORT
ATP-BINDING PROTEIN
CBIO 1

(Clostridium
perfringens) 		PF00005
(ABC_tran) 		4 PHE A  49
THR A  35
VAL A 162
ILE A 164
 None
 0.97A 2qbmA-3gfoA:
undetectable		 2qbmA-3gfoA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqp HEMOGLOBIN SUBUNIT
ALPHA

(Felis catus) 		PF00042
(Globin) 		4 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 143 (-3.7A)
None
HEM  A 143 ( 4.1A)
HEM  A 143 (-4.1A)
 0.91A 2qbmA-3gqpA:
undetectable		 2qbmA-3gqpA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0n UNCHARACTERIZED
PROTEIN DUF1470

(Jannaschia sp.
CCS1) 		PF07336
(ABATE)
PF11706
(zf-CGNR) 		4 THR A  22
THR A  71
ASP A 153
ILE A 146
 None
 0.89A 2qbmA-3h0nA:
undetectable		 2qbmA-3h0nA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjj MALTOSE
O-ACETYLTRANSFERASE

(Bacillus
anthracis) 		PF12464
(Mac)
PF14602
(Hexapep_2) 		4 PHE A  82
VAL A 108
VAL A  96
ILE A  98
 None
 0.84A 2qbmA-3hjjA:
undetectable		 2qbmA-3hjjA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'

(Sulfolobus
solfataricus) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 THR A 731
VAL A 511
THR A 510
VAL A 639
 None
 0.85A 2qbmA-3hkzA:
undetectable		 2qbmA-3hkzA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j23 CAPSID PROTEIN VP3

(Enterovirus A) 		PF00073
(Rhv) 		4 VAL C 165
THR C 166
VAL C 194
ILE C 196
 None
 0.92A 2qbmA-3j23C:
undetectable		 2qbmA-3j23C:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE

(Xanthomonas
campestris) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 PHE A  81
VAL A 111
VAL A  98
ILE A  95
 None
 0.74A 2qbmA-3l06A:
undetectable		 2qbmA-3l06A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Aeromonas
hydrophila) 		PF00106
(adh_short) 		4 PHE A 158
VAL A 120
THR A 119
ILE A 113
 None
 0.92A 2qbmA-3l6eA:
undetectable		 2qbmA-3l6eA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lb5 HIT-LIKE PROTEIN
INVOLVED IN
CELL-CYCLE
REGULATION

(Bartonella
henselae) 		PF01230
(HIT) 		4 VAL A  88
THR A  87
VAL A  77
ILE A  73
 None
 0.96A 2qbmA-3lb5A:
undetectable		 2qbmA-3lb5A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbe MHC CLASS II H2-IAG7
BETA CHAIN

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 PHE B 122
THR B 145
VAL B 129
ILE B 127
 None
 0.71A 2qbmA-3mbeB:
undetectable		 2qbmA-3mbeB:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Brucella suis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 THR A 108
VAL A 155
THR A 156
VAL A 163
 None
None
NAI  A 601 (-3.0A)
None
 0.92A 2qbmA-3meqA:
undetectable		 2qbmA-3meqA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2x UNCHARACTERIZED
PROTEIN YAGE

(Escherichia
coli) 		PF00701
(DHDPS) 		4 THR A 189
VAL A 199
ASP A 175
ILE A 173
 None
None
None
MCL  A 174 ( 3.6A)
 0.94A 2qbmA-3n2xA:
undetectable		 2qbmA-3n2xA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o6f HLA CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DRB1-4 BETA
CHAIN

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 PHE B 151
THR B 174
VAL B 158
ILE B 156
 None
 0.75A 2qbmA-3o6fB:
undetectable		 2qbmA-3o6fB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzl AGMATINE
UREOHYDROLASE

(Thermoplasma
volcanium) 		PF00491
(Arginase) 		5 PHE A 268
VAL A 254
VAL A 271
ASP A 269
ILE A 270
 None
 1.44A 2qbmA-3pzlA:
undetectable		 2qbmA-3pzlA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3smt HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3

(Homo sapiens) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		4 THR A 199
VAL A 193
VAL A 321
ILE A 322
 None
None
None
UNX  A 502 ( 4.8A)
 0.87A 2qbmA-3smtA:
undetectable		 2qbmA-3smtA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqi KLLA0E03807P

(Kluyveromyces
lactis) 		PF16787
(NDC10_II) 		4 VAL A 159
THR A 158
ASP A 142
ILE A 234
 None
 0.89A 2qbmA-3sqiA:
undetectable		 2qbmA-3sqiA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t79 KLLA0E03807P

(Kluyveromyces
lactis) 		PF16787
(NDC10_II) 		4 VAL A 159
THR A 158
ASP A 142
ILE A 234
 None
 0.90A 2qbmA-3t79A:
undetectable		 2qbmA-3t79A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tmc UNCHARACTERIZED
PROTEIN

(Bdellovibrio
bacteriovorus) 		PF13487
(HD_5) 		4 THR A 272
VAL A 154
THR A 153
ILE A 147
 DMS  A 312 (-4.3A)
None
DMS  A 312 (-2.9A)
None
 0.90A 2qbmA-3tmcA:
undetectable		 2qbmA-3tmcA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txa CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF00092
(VWA) 		4 TYR A 272
THR A 356
THR A 533
VAL A 538
 None
 0.87A 2qbmA-3txaA:
undetectable		 2qbmA-3txaA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9p NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Mus musculus) 		PF00061
(Lipocalin) 		5 PHE C  79
TYR C  50
THR C  48
VAL C 117
THR C 132
 None
 1.13A 2qbmA-3u9pC:
undetectable		 2qbmA-3u9pC:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uyq CARBONIC ANHYDRASE 3

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 PHE A 130
THR A 199
VAL A 142
ILE A 140
 None
 0.97A 2qbmA-3uyqA:
undetectable		 2qbmA-3uyqA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vbj GALACTOSIDE
O-ACETYLTRANSFERASE

(Bacillus cereus) 		PF00132
(Hexapep) 		4 VAL A  54
THR A  55
VAL A  42
ILE A  44
 None
 0.95A 2qbmA-3vbjA:
undetectable		 2qbmA-3vbjA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wuy NITRILASE

(Synechocystis
sp. PCC 6803) 		PF00795
(CN_hydrolase) 		4 VAL A 161
THR A 160
VAL A 130
ILE A 122
 None
 0.89A 2qbmA-3wuyA:
undetectable		 2qbmA-3wuyA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayg GLUCANSUCRASE

(Lactobacillus
reuteri) 		PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70) 		4 THR A 953
VAL A1521
VAL A1609
ILE A1542
 None
 0.96A 2qbmA-4aygA:
undetectable		 2qbmA-4aygA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b60 FIBRONECTIN-BINDING
PROTEIN A

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		4 VAL A 380
THR A 381
VAL A 397
ILE A 399
 None
 0.97A 2qbmA-4b60A:
undetectable		 2qbmA-4b60A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8x POSSIBLE
MARR-TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF12802
(MarR_2) 		4 THR A 115
VAL A  90
THR A  91
VAL A  98
 None
 0.87A 2qbmA-4b8xA:
undetectable		 2qbmA-4b8xA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqq INTEGRASE

(Streptomyces
virus phiC31) 		PF00239
(Resolvase) 		4 THR A 258
VAL A 277
THR A 276
ASP A 252
 None
 0.85A 2qbmA-4bqqA:
undetectable		 2qbmA-4bqqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bru ATP-DEPENDENT RNA
HELICASE DHH1

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		5 PHE A 100
VAL A 133
VAL A 121
ASP A 195
ILE A 119
 None
 1.46A 2qbmA-4bruA:
undetectable		 2qbmA-4bruA:
20.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		5 TYR A  98
THR A 103
VAL A 303
ASP A 305
ILE A 403
 None
GOL  A1419 (-3.8A)
GOL  A1419 (-3.9A)
HEM  A1418 (-2.7A)
None
 0.60A 2qbmA-4c9mA:
58.8		 2qbmA-4c9mA:
44.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cu8 GLYCOSIDE HYDROLASE
2

(Streptococcus
pneumoniae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		4 TYR A 424
THR A 331
VAL A 361
THR A 362
 None
 0.85A 2qbmA-4cu8A:
undetectable		 2qbmA-4cu8A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvu BETA-MANNOSIDASE

(Trichoderma
harzianum) 		PF00703
(Glyco_hydro_2) 		4 THR A 231
VAL A 299
THR A 300
VAL A 272
 None
None
NAG  A1961 ( 4.4A)
None
 0.96A 2qbmA-4cvuA:
undetectable		 2qbmA-4cvuA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d8p PEPTIDE FROM
GAMMA-GLIADIN,HLA
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DQ BETA 1
CHAIN

(Triticum
aestivum;
Homo sapiens) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 PHE B 122
THR B 145
VAL B 129
ILE B 127
 None
 0.67A 2qbmA-4d8pB:
undetectable		 2qbmA-4d8pB:
23.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 PHE A  87
THR A 101
VAL A 301
ILE A 401
 None
HEM  A 501 ( 4.8A)
PEG  A 502 ( 4.5A)
None
 0.94A 2qbmA-4dxyA:
51.9		 2qbmA-4dxyA:
46.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eae LMO1068 PROTEIN

(Listeria
monocytogenes) 		PF16781
(DUF5068) 		4 THR A 243
VAL A 152
VAL A 159
ILE A 117
 None
 0.93A 2qbmA-4eaeA:
undetectable		 2qbmA-4eaeA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eex ALCOHOL
DEHYDROGENASE 1

(Lactococcus
lactis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 THR A 103
VAL A 150
THR A 151
VAL A 158
 None
 0.90A 2qbmA-4eexA:
undetectable		 2qbmA-4eexA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewl 1D-MYO-INOSITOL
2-ACETAMIDO-2-DEOXY-
ALPHA-D-GLUCOPYRANOS
IDE DEACETYLASE

(Mycobacterium
tuberculosis) 		PF02585
(PIG-L) 		4 PHE A   9
THR A 183
VAL A 227
ILE A  25
 None
 0.92A 2qbmA-4ewlA:
undetectable		 2qbmA-4ewlA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f1n KPAGO

(Vanderwaltozyma
polyspora) 		PF02171
(Piwi) 		4 THR A 333
THR A 423
VAL A 396
ILE A 274
 None
 0.97A 2qbmA-4f1nA:
undetectable		 2qbmA-4f1nA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4z DNA POLYMERASE IV

(Sulfolobus
acidocaldarius;
Sulfolobus
solfataricus) 		no annotation 4 VAL B 183
VAL B 171
ASP B 231
ILE B 175
 None
 0.97A 2qbmA-4f4zB:
undetectable		 2qbmA-4f4zB:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4faj PRGZ

(Enterococcus
faecalis) 		PF00496
(SBP_bac_5) 		4 THR A 463
VAL A 443
VAL A 338
ILE A 342
 None
 0.83A 2qbmA-4fajA:
undetectable		 2qbmA-4fajA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gh7 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		PF00061
(Lipocalin) 		4 PHE A  27
THR A  54
THR A 136
VAL A 108
 None
 0.79A 2qbmA-4gh7A:
undetectable		 2qbmA-4gh7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gh7 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		PF00061
(Lipocalin) 		4 PHE A  83
THR A  54
VAL A 121
THR A 136
 None
 0.96A 2qbmA-4gh7A:
undetectable		 2qbmA-4gh7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gh7 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		PF00061
(Lipocalin) 		4 TYR A  56
THR A  54
VAL A 121
THR A 136
 None
 0.94A 2qbmA-4gh7A:
undetectable		 2qbmA-4gh7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gt6 CELL SURFACE PROTEIN

(Faecalibacterium
prausnitzii) 		PF13306
(LRR_5) 		4 PHE A 159
VAL A 151
VAL A 118
ILE A 145
 None
 0.91A 2qbmA-4gt6A:
undetectable		 2qbmA-4gt6A:
23.66