SIMILAR PATTERNS OF AMINO ACIDS FOR 2QBL_A_CAMA517

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezr NUCLEOSIDE HYDROLASE

(Leishmania
major) 		PF01156
(IU_nuc_hydro) 		4 LEU A  42
VAL A  45
THR A  46
ASP A   8
 None
 0.72A 2qblA-1ezrA:
0.0		 2qblA-1ezrA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hsk UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Staphylococcus
aureus) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 PHE A 240
LEU A 257
VAL A 297
THR A 296
 None
 0.93A 2qblA-1hskA:
0.0		 2qblA-1hskA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iok CHAPERONIN 60

(Paracoccus
denitrificans) 		PF00118
(Cpn60_TCP1) 		4 LEU A  31
THR A  90
VAL A 500
ASP A 496
 None
 0.98A 2qblA-1iokA:
0.0		 2qblA-1iokA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ji6 PESTICIDIAL CRYSTAL
PROTEIN CRY3BB

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 PHE A 343
LEU A 476
THR A 403
VAL A 421
 None
 0.78A 2qblA-1ji6A:
0.0		 2qblA-1ji6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldj CULLIN HOMOLOG 1

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 TYR A 157
LEU A 162
VAL A 165
THR A 166
 None
 0.88A 2qblA-1ldjA:
0.0		 2qblA-1ldjA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus) 		PF01709
(Transcrip_reg) 		4 PHE A 117
LEU A 222
VAL A 234
VAL A 130
 None
 0.89A 2qblA-1lfpA:
0.0		 2qblA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqt FPRA

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 PHE A 128
TYR A 132
THR A 168
VAL A 194
 None
 1.00A 2qblA-1lqtA:
0.0		 2qblA-1lqtA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nd7 WW DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 831
LEU A 847
VAL A 850
THR A 851
 None
 0.97A 2qblA-1nd7A:
0.0		 2qblA-1nd7A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlq NUCLEOPLASMIN-LIKE
PROTEIN

(Drosophila
melanogaster) 		PF03066
(Nucleoplasmin) 		4 TYR A   7
VAL A  86
THR A  87
VAL A  51
 None
 0.99A 2qblA-1nlqA:
undetectable		 2qblA-1nlqA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1r PUTIDAREDOXIN
REDUCTASE

(Pseudomonas
putida) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 PHE A 329
LEU A 185
VAL A 188
THR A 189
 None
 0.91A 2qblA-1q1rA:
undetectable		 2qblA-1q1rA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r30 BIOTIN SYNTHASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06968
(BATS) 		4 LEU A   9
VAL A  12
THR A  13
ASP A 201
 None
 0.60A 2qblA-1r30A:
undetectable		 2qblA-1r30A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rc2 AQUAPORIN Z

(Escherichia
coli) 		no annotation 4 PHE B 145
LEU B  15
VAL B  47
THR B  46
 None
 0.95A 2qblA-1rc2B:
undetectable		 2qblA-1rc2B:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxm DNA POLYMERASE
SLIDING CLAMP

(Archaeoglobus
fulgidus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A  11
VAL A  14
THR A  15
VAL A  69
 None
 0.84A 2qblA-1rxmA:
undetectable		 2qblA-1rxmA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1viw ALPHA-AMYLASE-INHIBI
TOR

(Phaseolus
vulgaris) 		PF00139
(Lectin_legB) 		4 PHE B  62
VAL B  98
THR B  99
VAL B 148
 None
 0.93A 2qblA-1viwB:
undetectable		 2qblA-1viwB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wps HUT OPERON POSITIVE
REGULATORY PROTEIN

(Bacillus
subtilis) 		PF09021
(HutP) 		4 LEU A  83
VAL A  86
THR A  87
VAL A 100
 None
 0.72A 2qblA-1wpsA:
undetectable		 2qblA-1wpsA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xau B- AND T-LYMPHOCYTE
ATTENUATOR

(Mus musculus) 		PF13895
(Ig_2) 		5 PHE A  82
VAL A 109
THR A 110
VAL A 113
ASP A  89
 None
 1.43A 2qblA-1xauA:
undetectable		 2qblA-1xauA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xf1 C5A PEPTIDASE

(Streptococcus
pyogenes) 		PF00082
(Peptidase_S8)
PF02225
(PA)
PF06280
(fn3_5)
PF13585
(CHU_C) 		4 LEU A 645
VAL A 628
VAL A 602
ASP A 604
 None
 0.99A 2qblA-1xf1A:
undetectable		 2qblA-1xf1A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yyr TRICHODIENE SYNTHASE

(Fusarium
sporotrichioides) 		PF06330
(TRI5) 		4 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.85A 2qblA-1yyrA:
undetectable		 2qblA-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ast S-PHASE
KINASE-ASSOCIATED
PROTEIN 1A

(Homo sapiens) 		PF01466
(Skp1)
PF03931
(Skp1_POZ) 		4 LEU A1115
VAL A1118
THR A1119
VAL A1095
 None
 0.72A 2qblA-2astA:
undetectable		 2qblA-2astA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN

(Streptococcus
pneumoniae) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 PHE A  11
LEU A  77
VAL A  34
VAL A  38
 None
 0.88A 2qblA-2awaA:
undetectable		 2qblA-2awaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awg 38 KDA FK-506
BINDING PROTEIN

(Homo sapiens) 		PF00254
(FKBP_C) 		4 LEU A 200
VAL A 198
VAL A 152
ASP A 157
 None
 0.93A 2qblA-2awgA:
undetectable		 2qblA-2awgA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu9 HISTONE CHAPERONE
CIA1

(Schizosaccharomyces
pombe) 		PF04729
(ASF1_hist_chap) 		4 TYR A  22
VAL A 114
THR A  94
VAL A 141
 None
 0.97A 2qblA-2cu9A:
undetectable		 2qblA-2cu9A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE

(Candida
albicans) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 LEU A 175
VAL A 178
THR A 179
ASP A 166
 None
 0.98A 2qblA-2dkdA:
undetectable		 2qblA-2dkdA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ets HYPOTHETICAL PROTEIN

(Staphylococcus
aureus) 		PF08807
(DUF1798) 		4 LEU A 106
VAL A 109
THR A 110
ASP A   3
 None
 0.88A 2qblA-2etsA:
undetectable		 2qblA-2etsA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gze COLICIN-E9 IMMUNITY
PROTEIN

(Escherichia
coli) 		PF01320
(Colicin_Pyocin) 		4 LEU A  16
VAL A  19
THR A  20
ASP A  61
 None
 0.54A 2qblA-2gzeA:
undetectable		 2qblA-2gzeA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i62 NICOTINAMIDE
N-METHYLTRANSFERASE

(Mus musculus) 		PF01234
(NNMT_PNMT_TEMT) 		4 PHE A 254
LEU A 194
VAL A 226
ASP A 198
 None
 0.95A 2qblA-2i62A:
undetectable		 2qblA-2i62A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqf CATALASE

(Helicobacter
pylori) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 LEU A 174
VAL A 177
THR A 178
VAL A 479
 None
MHO  A 181 ( 4.5A)
None
None
 0.88A 2qblA-2iqfA:
undetectable		 2qblA-2iqfA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k8d PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRB

(Methanothermobacter
thermautotrophicus) 		PF01641
(SelR) 		4 PHE A  90
LEU A 123
VAL A 114
VAL A  94
 None
 0.94A 2qblA-2k8dA:
undetectable		 2qblA-2k8dA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		6 PHE A  87
TYR A  96
LEU A 244
VAL A 247
VAL A 295
ASP A 297
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
None
HEM  A 501 (-4.6A)
HEM  A 501 (-2.8A)
 0.22A 2qblA-2m56A:
69.6		 2qblA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 PHE A  87
TYR A  96
LEU A 244
VAL A 396
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
None
 0.67A 2qblA-2m56A:
69.6		 2qblA-2m56A:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mas INOSINE-URIDINE
NUCLEOSIDE
N-RIBOHYDROLASE

(Crithidia
fasciculata) 		PF01156
(IU_nuc_hydro) 		4 LEU A  42
VAL A  45
THR A  46
ASP A   8
 None
 0.76A 2qblA-2masA:
undetectable		 2qblA-2masA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqm PROTEIN HNRNPL

(Rattus
norvegicus) 		PF00076
(RRM_1) 		4 TYR A 254
VAL A 207
THR A 204
VAL A 229
 None
 0.91A 2qblA-2mqmA:
undetectable		 2qblA-2mqmA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ovi HYPOTHETICAL PROTEIN
CHUX

(Escherichia
coli) 		PF06228
(ChuX_HutX) 		4 PHE A 124
LEU A 156
VAL A  54
THR A  53
 None
 0.76A 2qblA-2oviA:
undetectable		 2qblA-2oviA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uun C-PHYCOCYANIN

(Leptolyngbya
sp.) 		PF00502
(Phycobilisome) 		4 LEU B  90
VAL B  93
THR B  94
VAL B 142
 None
None
None
BLA  B 255 (-4.5A)
 0.99A 2qblA-2uunB:
undetectable		 2qblA-2uunB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa) 		PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc) 		4 LEU A  82
VAL A  85
THR A  86
VAL A 338
 None
 0.92A 2qblA-2vz9A:
undetectable		 2qblA-2vz9A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE

(Staphylococcus
aureus) 		PF00391
(PEP-utilizers)
PF02896
(PEP-utilizers_C)
PF05524
(PEP-utilisers_N) 		4 LEU A 106
VAL A 109
THR A 110
VAL A  81
 None
 0.99A 2qblA-2wqdA:
undetectable		 2qblA-2wqdA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 TYR A 227
LEU A 279
VAL A 278
VAL A 223
 None
 0.92A 2qblA-3b9tA:
undetectable		 2qblA-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdz P450CIN

(Citrobacter
braakii) 		PF00067
(p450) 		4 LEU A  88
VAL A  76
THR A  77
VAL A 386
 None
 0.92A 2qblA-3bdzA:
48.4		 2qblA-3bdzA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkw S-ADENOSYLMETHIONINE
DEPENDENT
METHYLTRANSFERASE

(Mesorhizobium
japonicum) 		PF08241
(Methyltransf_11) 		4 LEU A 102
VAL A 129
THR A 128
VAL A 119
 None
 0.93A 2qblA-3bkwA:
undetectable		 2qblA-3bkwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8f PYRUVATE
FORMATE-LYASE
1-ACTIVATING ENZYME

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF13353
(Fer4_12) 		4 LEU A 119
VAL A 122
THR A 123
VAL A  73
 None
 0.96A 2qblA-3c8fA:
undetectable		 2qblA-3c8fA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxa SIS DOMAIN PROTEIN

(Listeria
monocytogenes) 		PF01380
(SIS) 		4 LEU A  24
VAL A  27
THR A  28
VAL A 124
 None
 0.85A 2qblA-3fxaA:
undetectable		 2qblA-3fxaA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7r PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		4 LEU A 138
VAL A 141
THR A 142
VAL A 190
 None
 0.87A 2qblA-3g7rA:
undetectable		 2qblA-3g7rA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxa OUTER MEMBRANE
LIPOPROTEIN GNA1946

(Neisseria
meningitidis) 		PF03180
(Lipoprotein_9) 		4 LEU A 252
VAL A 255
THR A 256
VAL A 121
 None
 0.92A 2qblA-3gxaA:
undetectable		 2qblA-3gxaA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN

(Pseudomonas
protegens) 		PF13407
(Peripla_BP_4) 		4 LEU A 190
VAL A 192
THR A 193
VAL A 122
 None
None
SO4  A 400 ( 3.9A)
None
 0.90A 2qblA-3h75A:
undetectable		 2qblA-3h75A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'
DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus;
Sulfolobus
solfataricus) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 LEU B1001
THR A 324
VAL B 887
ASP B 876
 None
 0.87A 2qblA-3hkzB:
undetectable		 2qblA-3hkzB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ir1 OUTER MEMBRANE
LIPOPROTEIN GNA1946

(Neisseria
meningitidis) 		PF03180
(Lipoprotein_9) 		4 LEU A 252
VAL A 255
THR A 256
VAL A 121
 None
 0.94A 2qblA-3ir1A:
undetectable		 2qblA-3ir1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwk AMINOALDEHYDE
DEHYDROGENASE

(Pisum sativum) 		PF00171
(Aldedh) 		4 LEU A 314
VAL A 283
THR A 282
ASP A 276
 None
 0.99A 2qblA-3iwkA:
undetectable		 2qblA-3iwkA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jxv 70 KDA
PEPTIDYL-PROLYL
ISOMERASE

(Triticum
aestivum) 		PF00254
(FKBP_C) 		4 LEU A 380
VAL A 378
VAL A 330
ASP A 335
 None
 0.95A 2qblA-3jxvA:
undetectable		 2qblA-3jxvA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum) 		PF02580
(Tyr_Deacylase) 		4 LEU A  79
VAL A  76
VAL A 151
ASP A 148
 None
 0.97A 2qblA-3ko7A:
undetectable		 2qblA-3ko7A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6e OXIDOREDUCTASE,
SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Aeromonas
hydrophila) 		PF00106
(adh_short) 		4 PHE A 158
LEU A 130
VAL A 120
THR A 119
 None
 0.89A 2qblA-3l6eA:
undetectable		 2qblA-3l6eA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llq AQUAPORIN Z 2

(Agrobacterium
fabrum) 		PF00230
(MIP) 		4 PHE A 143
LEU A  15
VAL A  47
THR A  46
 None
 0.96A 2qblA-3llqA:
undetectable		 2qblA-3llqA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lur PUTATIVE BACTERIAL
TRANSCRIPTION
REGULATION PROTEIN

(Staphylococcus
aureus) 		PF06445
(GyrI-like) 		4 PHE A  99
TYR A   3
VAL A 155
THR A 127
 None
 0.98A 2qblA-3lurA:
undetectable		 2qblA-3lurA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p27 ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3) 		4 LEU A 420
VAL A 421
THR A 475
ASP A 448
 None
 1.00A 2qblA-3p27A:
undetectable		 2qblA-3p27A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvl MYOSIN VIIA ISOFORM
1

(Mus musculus) 		PF00784
(MyTH4) 		4 PHE A1532
LEU A1511
VAL A1498
VAL A1489
 None
None
None
GOL  A   1 ( 4.7A)
 0.92A 2qblA-3pvlA:
undetectable		 2qblA-3pvlA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C

(Homo sapiens) 		PF00617
(RasGEF) 		4 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.96A 2qblA-3t6gA:
undetectable		 2qblA-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr9 DIHYDROPTEROATE
SYNTHASE

(Coxiella
burnetii) 		PF00809
(Pterin_bind) 		4 PHE A 202
LEU A 172
VAL A 175
VAL A 231
 None
 0.82A 2qblA-3tr9A:
undetectable		 2qblA-3tr9A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx1 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Listeria
monocytogenes) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 PHE A 222
LEU A 239
VAL A 279
THR A 278
 None
 0.92A 2qblA-3tx1A:
undetectable		 2qblA-3tx1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ukf UDP-GALACTOPYRANOSE
MUTASE

(Aspergillus
fumigatus) 		PF13450
(NAD_binding_8) 		4 LEU A 188
VAL A 191
THR A 192
ASP A 123
 None
 0.95A 2qblA-3ukfA:
undetectable		 2qblA-3ukfA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umf ADENYLATE KINASE

(Schistosoma
mansoni) 		PF00406
(ADK) 		4 PHE A  13
TYR A  96
LEU A  74
VAL A 110
 None
 0.88A 2qblA-3umfA:
undetectable		 2qblA-3umfA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akr F-ACTIN-CAPPING
PROTEIN SUBUNIT
ALPHA
F-ACTIN-CAPPING
PROTEIN SUBUNIT BETA

(Dictyostelium
discoideum;
Dictyostelium
discoideum) 		PF01267
(F-actin_cap_A)
PF01115
(F_actin_cap_B) 		4 LEU A 202
VAL B 189
THR A 204
ASP A 240
 None
 0.87A 2qblA-4akrA:
undetectable		 2qblA-4akrA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4azw WBDD

(Escherichia
coli) 		PF00069
(Pkinase)
PF13847
(Methyltransf_31) 		4 LEU A  37
THR A  41
VAL A  57
ASP A  59
 None
 0.92A 2qblA-4azwA:
undetectable		 2qblA-4azwA:
21.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 TYR A  98
LEU A 252
VAL A 303
ASP A 305
 None
HEM  A1418 (-4.0A)
GOL  A1419 (-3.9A)
HEM  A1418 (-2.7A)
 0.54A 2qblA-4c9mA:
58.1		 2qblA-4c9mA:
44.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4coy EPITHELIAL ADHESIN 6

([Candida]
glabrata) 		PF10528
(GLEYA) 		4 TYR A 113
LEU A 122
THR A 120
ASP A 229
 None
 0.90A 2qblA-4coyA:
undetectable		 2qblA-4coyA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw9 THIOREDOXIN

(Entamoeba
histolytica) 		PF00085
(Thioredoxin) 		4 PHE A  26
LEU A   9
THR A  13
VAL A  79
 None
 0.92A 2qblA-4cw9A:
undetectable		 2qblA-4cw9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF13306
(LRR_5) 		5 PHE A 235
LEU A 230
VAL A 252
THR A 250
VAL A 268
 None
 1.43A 2qblA-4fs7A:
undetectable		 2qblA-4fs7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0m C-PHYCOCYANIN BETA
CHAIN

(Synechococcus
elongatus) 		PF00502
(Phycobilisome) 		4 LEU B  90
VAL B  93
THR B  94
VAL B 142
 None
None
None
CYC  B 202 (-4.2A)
 0.93A 2qblA-4h0mB:
undetectable		 2qblA-4h0mB:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb4 EXPORTIN-1

(Saccharomyces
cerevisiae) 		PF03810
(IBN_N)
PF08389
(Xpo1)
PF08767
(CRM1_C) 		4 LEU C 329
VAL C 276
THR C 275
ASP C 269
 None
 0.92A 2qblA-4hb4C:
undetectable		 2qblA-4hb4C:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ic5 PROTEASE DO-LIKE 5,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF13365
(Trypsin_2) 		4 PHE A 134
LEU A 189
VAL A 309
THR A 308
 None
 0.87A 2qblA-4ic5A:
undetectable		 2qblA-4ic5A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10

(Mycobacterium
tuberculosis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 266
VAL A 291
THR A 264
VAL A 285
 None
 0.93A 2qblA-4isbA:
undetectable		 2qblA-4isbA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixk FERRITIN

(Pseudo-nitzschia
multiseries) 		PF00210
(Ferritin) 		4 LEU A 138
VAL A 141
THR A 142
ASP A  85
 None
 0.93A 2qblA-4ixkA:
undetectable		 2qblA-4ixkA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jq9 DIHYDROLIPOYL
DEHYDROGENASE

(Escherichia
coli) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A  57
VAL A 193
THR A 192
VAL A 180
 GOL  A 505 (-3.9A)
None
None
None
 0.93A 2qblA-4jq9A:
undetectable		 2qblA-4jq9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3y NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 PHE A 121
LEU A 192
VAL A 191
THR A 190
 None
 0.97A 2qblA-4k3yA:
undetectable		 2qblA-4k3yA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7v PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Vibrio cholerae) 		PF01135
(PCMT) 		4 LEU A 146
VAL A 147
THR A 148
VAL A 197
 None
None
SAH  A 301 (-3.4A)
None
 0.97A 2qblA-4l7vA:
undetectable		 2qblA-4l7vA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgs ALCOHOL
DEHYDROGENASE YQHD

(Escherichia
coli) 		PF00465
(Fe-ADH) 		4 PHE A 334
LEU A 221
VAL A 200
THR A 199
 None
 0.93A 2qblA-4qgsA:
undetectable		 2qblA-4qgsA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rsi STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2

(Saccharomyces
cerevisiae) 		PF06470
(SMC_hinge) 		4 LEU A 697
VAL A 700
THR A 701
ASP A 484
 None
 0.93A 2qblA-4rsiA:
undetectable		 2qblA-4rsiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4std SCYTALONE
DEHYDRATASE

(Magnaporthe
grisea) 		PF02982
(Scytalone_dh) 		4 PHE A  53
TYR A  50
VAL A  75
VAL A 108
 None
BFS  A 173 (-4.3A)
BFS  A 173 (-4.5A)
BFS  A 173 ( 4.4A)
 0.98A 2qblA-4stdA:
undetectable		 2qblA-4stdA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4toi 30S RIBOSOMAL
PROTEIN S2,RIBOSOMAL
PROTEIN S1

(Escherichia
coli) 		PF00318
(Ribosomal_S2)
PF00575
(S1) 		4 PHE A  69
LEU A  57
VAL A 221
THR A 220
 None
 0.93A 2qblA-4toiA:
undetectable		 2qblA-4toiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wgk NEUTRAL CERAMIDASE

(Homo sapiens) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		4 PHE A 341
VAL A 283
VAL A 287
ASP A 293
 None
 0.96A 2qblA-4wgkA:
undetectable		 2qblA-4wgkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y96 TRIOSEPHOSPHATE
ISOMERASE

(Gemmata
obscuriglobus) 		PF00121
(TIM) 		4 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.97A 2qblA-4y96A:
undetectable		 2qblA-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a01 O-GLYCOSYLTRANSFERAS
E

(Drosophila
melanogaster) 		PF13374
(TPR_10)
PF13414
(TPR_11)
PF13844
(Glyco_transf_41) 		4 PHE A 922
LEU A 878
VAL A 910
THR A 909
 None
 0.96A 2qblA-5a01A:
undetectable		 2qblA-5a01A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2

(Human
immunodeficiency
virus 2) 		PF00516
(GP120) 		4 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.94A 2qblA-5cayG:
undetectable		 2qblA-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5v PRP38

(Chaetomium
thermophilum) 		PF03371
(PRP38) 		4 TYR A 105
LEU A 119
VAL A  65
VAL A  56
 None
 0.99A 2qblA-5f5vA:
undetectable		 2qblA-5f5vA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gte LACHRYMATORY-FACTOR
SYNTHASE

(Allium cepa) 		PF10604
(Polyketide_cyc2) 		4 PHE A 104
TYR A 114
LEU A 152
VAL A  73
 None
 0.83A 2qblA-5gteA:
undetectable		 2qblA-5gteA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT ZETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		4 LEU z 328
VAL z 331
THR z 332
VAL z 354
 None
 0.94A 2qblA-5gw5z:
undetectable		 2qblA-5gw5z:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hei NFRA2

(Bacillus
megaterium) 		PF00881
(Nitroreductase) 		4 LEU A  97
VAL A  99
THR A 100
ASP A  82
 None
 0.92A 2qblA-5heiA:
undetectable		 2qblA-5heiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hva DR2231

(Deinococcus
radiodurans) 		PF01503
(PRA-PH) 		4 LEU A  83
VAL A  86
THR A  87
ASP A  45
 None
 0.86A 2qblA-5hvaA:
undetectable		 2qblA-5hvaA:
16.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5kyo CYP101J2

(Sphingobium
yanoikuyae) 		PF00067
(p450) 		4 LEU A 195
VAL A 198
THR A 199
VAL A 249
 None
 0.85A 2qblA-5kyoA:
50.0		 2qblA-5kyoA:
40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldd MON1
CCZ1

(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		PF03164
(Mon1)
PF08217
(DUF1712) 		4 PHE B 114
LEU A 226
VAL A 287
VAL A 274
 None
 0.98A 2qblA-5lddB:
undetectable		 2qblA-5lddB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 LEU A1899
VAL A1902
THR A1903
VAL A1967
 None
 0.89A 2qblA-5m59A:
undetectable		 2qblA-5m59A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nsq AMINOPEPTIDASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00883
(Peptidase_M17) 		4 LEU A 269
VAL A 270
THR A 271
VAL A 319
 None
 0.95A 2qblA-5nsqA:
undetectable		 2qblA-5nsqA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ntf AMINOPEPTIDASE

(Trypanosoma
cruzi) 		PF00883
(Peptidase_M17) 		4 LEU A 268
VAL A 269
THR A 270
VAL A 318
 None
 0.95A 2qblA-5ntfA:
undetectable		 2qblA-5ntfA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy7 NEURONAL PAS
DOMAIN-CONTAINING
PROTEIN 3

(Mus musculus) 		PF00010
(HLH)
PF00989
(PAS)
PF08447
(PAS_3) 		4 PHE B 176
LEU B 187
VAL B 183
VAL B 318
 None
 0.95A 2qblA-5sy7B:
undetectable		 2qblA-5sy7B:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tsq IUNH

(Leishmania
braziliensis) 		PF01156
(IU_nuc_hydro) 		4 LEU A  42
VAL A  45
THR A  46
ASP A   8
 None
 0.75A 2qblA-5tsqA:
undetectable		 2qblA-5tsqA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu3 SPECKLE TARGETED
PIP5K1A-REGULATED
POLY(A) POLYMERASE

(Homo sapiens) 		PF03828
(PAP_assoc) 		4 LEU A 396
THR A 435
VAL A 551
ASP A 543
 None
EDO  A1004 (-3.7A)
UTP  A1001 ( 4.4A)
None
 0.96A 2qblA-5wu3A:
undetectable		 2qblA-5wu3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu6 SPECKLE TARGETED
PIP5K1A-REGULATED
POLY(A) POLYMERASE

(Homo sapiens) 		PF00076
(RRM_1)
PF03828
(PAP_assoc) 		4 LEU A 396
THR A 435
VAL A 551
ASP A 543
 None
 0.97A 2qblA-5wu6A:
undetectable		 2qblA-5wu6A:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xaz GAMMA-BUTYROLACTONE
RECEPTOR PROTEIN

(Streptomyces
fradiae) 		PF00440
(TetR_N) 		4 LEU A 176
VAL A 179
THR A 180
ASP A  83
 None
 0.91A 2qblA-5xazA:
undetectable		 2qblA-5xazA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6avh GH3.15 ACYL ACID
AMIDO SYNTHETASE

(Arabidopsis
thaliana) 		no annotation 4 LEU A 445
VAL A 448
THR A 449
ASP A 464
 None
 0.89A 2qblA-6avhA:
undetectable		 2qblA-6avhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c3p ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8

(Homo sapiens) 		no annotation 4 PHE E 613
VAL E1207
THR E1206
VAL E 421
 None
 0.92A 2qblA-6c3pE:
undetectable		 2qblA-6c3pE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k ACTF

(Rhodothermus
marinus) 		no annotation 5 PHE F 158
TYR F 127
LEU F  67
THR F  71
ASP F 216
 None
 1.45A 2qblA-6f0kF:
undetectable		 2qblA-6f0kF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f79 -

(-) 		no annotation 4 PHE A   2
LEU A  67
VAL A  76
THR A  75
 None
 0.92A 2qblA-6f79A:
undetectable		 2qblA-6f79A:
undetectable